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Wyszukujesz frazę ""Down Syndrome"" wg kryterium: Temat


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Tytuł :
Repeat tympanostomy tubes in children with Down syndrome.
Autorzy :
Omar M; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
McCoy JL; UPMC Children's Hospital of Pittsburgh, Department of Otolaryngology, Pittsburgh, PA, USA.
McCormick AA; UPMC Children's Hospital of Pittsburgh, Down Syndrome Center of Western PA, Pittsburgh, PA, USA.
Vellody K; UPMC Children's Hospital of Pittsburgh, Down Syndrome Center of Western PA, Pittsburgh, PA, USA.
Chi DH; UPMC Children's Hospital of Pittsburgh, Department of Otolaryngology, Pittsburgh, PA, USA. Electronic address: .
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Źródło :
International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2021 Sep; Vol. 148, pp. 110811. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*/complications
Down Syndrome*/epidemiology
Otitis Media with Effusion*/epidemiology
Otitis Media with Effusion*/surgery
Case-Control Studies ; Child ; Humans ; Infant ; Middle Ear Ventilation ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Trisomy 21 results in modest impacts on mitochondrial function and central carbon metabolism.
Autorzy :
Anderson CC; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA.
Marentette JO; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA.
Prutton KM; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado, Aurora, CO, USA.
Rauniyar AK; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA.
Reisz JA; Department of Biochemistry and Molecular Genetics, USA.
D'Alessandro A; Department of Biochemistry and Molecular Genetics, USA.
Maclean KN; Department of Pediatrics, USA; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado, Aurora, CO, USA.
Saba LM; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA.
Roede JR; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, USA; Linda Crnic Institute for Down Syndrome, School of Medicine, University of Colorado, Aurora, CO, USA. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Aug 20; Vol. 172, pp. 201-212. Date of Electronic Publication: 2021 Jun 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Down Syndrome*/genetics
Down Syndrome*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Carbon/metabolism ; Cells, Cultured ; Humans ; Mitochondria
Czasopismo naukowe
Tytuł :
Is the estimated glomerular filtration rate formula useful for evaluating the renal function of Down syndrome?
Autorzy :
Nishino T; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.; Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan.
Endo S; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Miyano H; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Umeda C; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Tomii Y; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Watanabe Y; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Nakagawa M; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Kakegawa D; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
Fujinaga S; Division of Nephrology, Saitama Children's Medical Center, Saitama, Japan.
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Źródło :
Pediatrics international : official journal of the Japan Pediatric Society [Pediatr Int] 2021 Aug; Vol. 63 (8), pp. 944-950. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*/complications
Down Syndrome*/diagnosis
Creatinine ; Female ; Glomerular Filtration Rate ; Humans ; Kidney/diagnostic imaging ; Kidney/physiology ; Male ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
The impact of obstructive sleep apnea on bronchiolitis severity in children with Down syndrome.
Autorzy :
Tsou PY; Department of Pediatrics, Driscoll Children's Hospital, Corpus Christi, TX, USA; Sleep Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Cielo CM; Sleep Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Xanthopoulos MS; Sleep Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Wang YH; Department of Pediatrics, Driscoll Children's Hospital, Corpus Christi, TX, USA.
Kuo PL; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Tapia IE; Sleep Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło :
Sleep medicine [Sleep Med] 2021 Jul; Vol. 83, pp. 188-195. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bronchiolitis*/complications
Bronchiolitis*/epidemiology
Down Syndrome*/complications
Down Syndrome*/epidemiology
Sleep Apnea, Obstructive*/complications
Sleep Apnea, Obstructive*/epidemiology
Child ; Comorbidity ; Humans ; Odds Ratio
Czasopismo naukowe
Tytuł :
Aberrant myelomonocytic CD56 expression in Down syndrome is frequent and not associated with leukemogenesis.
Autorzy :
Gadgeel M; Children's Hospital of Michigan, Division of Hematology/Oncology, Hematology/Oncology Flow Cytometry Laboratory, Detroit, MI, USA.
AlQanber B; Children's Hospital of Michigan, Division of Hematology/Oncology, Hematology/Oncology Flow Cytometry Laboratory, Detroit, MI, USA.
Buck S; Children's Hospital of Michigan, Division of Hematology/Oncology, Hematology/Oncology Flow Cytometry Laboratory, Detroit, MI, USA.
Taub JW; Children's Hospital of Michigan, Division of Hematology/Oncology, Barbara Ann Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, MI, USA.
Ravindranath Y; Children's Hospital of Michigan, Division of Hematology/Oncology, Hematology/Oncology Flow Cytometry Laboratory, Detroit, MI, USA.; Children's Hospital of Michigan, Division of Hematology/Oncology, Barbara Ann Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, MI, USA.
Savaşan S; Children's Hospital of Michigan, Division of Hematology/Oncology, Hematology/Oncology Flow Cytometry Laboratory, Detroit, MI, USA. .; Children's Hospital of Michigan, Division of Hematology/Oncology, Pediatric Blood and Marrow Transplant Program, Barbara Ann Karmanos Cancer Center, Central Michigan University College of Medicine, 3901 Beaubien Blvd., Detroit, MI, 48201, USA. .
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Źródło :
Annals of hematology [Ann Hematol] 2021 Jul; Vol. 100 (7), pp. 1695-1700. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Myelopoiesis*
CD56 Antigen/*biosynthesis
Down Syndrome/*genetics
Granulocytes/*metabolism
Monocytes/*metabolism
Antigens, CD/analysis ; CD56 Antigen/genetics ; Cell Transformation, Neoplastic ; Child, Preschool ; Core Binding Factor Alpha 2 Subunit/biosynthesis ; Core Binding Factor Alpha 2 Subunit/genetics ; Down Syndrome/metabolism ; Down Syndrome/physiopathology ; Flow Cytometry ; Gene Expression Regulation ; Humans ; Infant ; Leukemia, Myeloid ; Leukocytosis/etiology ; Retrospective Studies ; Thrombocytopenia/etiology
Czasopismo naukowe
Tytuł :
Molecular basis of immunoglobulin heavy constant G4 gene ( IGHG4 )-related low serum IgG4 subclasses in Down syndrome.
Autorzy :
Jeraiby MA; From the Department of Biochemistry, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
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Źródło :
Saudi medical journal [Saudi Med J] 2021 Sep; Vol. 42 (9), pp. 975-980.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*/genetics
Immunoglobulin G*
Humans ; Prospective Studies
Czasopismo naukowe
Tytuł :
Repeat Pediatric Trisomy 21 Radiographic Exam: Does Atlantoaxial Instability Develop Over Time?
Autorzy :
Bauer JM; Seattle Children's Hospital Department of Orthopaedic Surgery, University of Washington Department of Orthopaedics and Sports Medicine.
Dhaliwal VK; University of Washington School of Medicine.
Browd SR; Seattle Children's Hospital Department of Neurosurgery, University of Washington Department of Neurosurgery, Seattle, WA.
Krengel WF 3rd; Seattle Children's Hospital Department of Orthopaedic Surgery, University of Washington Department of Orthopaedics and Sports Medicine.
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Źródło :
Journal of pediatric orthopedics [J Pediatr Orthop] 2021 Sep 01; Vol. 41 (8), pp. e646-e650.
Typ publikacji :
Journal Article
MeSH Terms :
Atlanto-Axial Joint*/diagnostic imaging
Down Syndrome*/complications
Down Syndrome*/diagnostic imaging
Joint Instability*/diagnostic imaging
Joint Instability*/epidemiology
Joint Instability*/etiology
Spinal Diseases*
Cervical Vertebrae/diagnostic imaging ; Child ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Facial analysis technology for the detection of Down syndrome in the Democratic Republic of the Congo.
Autorzy :
Porras AR; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: .
Bramble MS; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA.
Mosema Be Amoti K; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; Biamba Marie Mutombo Hospital, Kinshasa, Democratic Republic of the Congo; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo.
Spencer D; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA.
Dakande C; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo.
Manya H; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo.
Vashist N; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Likuba E; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo.
Ebwel JM; Université Pédagogique Nationale, Kinshasa, Democratic Republic of the Congo.
Musasa C; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; Faculty of Medicine, Congo Protestant University, Kinshasa, Université Protestante au Congo.
Malherbe H; University of KwaZulu Natal, Durban, South Africa.
Mohammed B; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Tor-Diez C; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA.
Ngoyi DM; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo; Department of Tropical Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Katumbay DT; Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo; Department of Neurology and School of Public Health, Oregon Health & Science University, Portland, OR, USA.
Linguraru MG; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington, DC, USA; Departments of Radiology Pediatrics and Biomedical Engineering, George Washington University, Washington, DC, USA. Electronic address: .
Vilain E; Center for Genetic Medicine Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA; International Research Laboratory of Epigenetics, Data, Politics, Centre National de la Recherche Scientifique, Washington, DC, USA; Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA. Electronic address: .
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Źródło :
European journal of medical genetics [Eur J Med Genet] 2021 Sep; Vol. 64 (9), pp. 104267. Date of Electronic Publication: 2021 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Facies*
Automated Facial Recognition/*methods
Down Syndrome/*pathology
Image Processing, Computer-Assisted/*methods
Automated Facial Recognition/economics ; Automated Facial Recognition/standards ; Democratic Republic of the Congo ; Developing Countries ; Down Syndrome/genetics ; Genetic Testing ; Humans ; Image Processing, Computer-Assisted/economics ; Image Processing, Computer-Assisted/standards ; Machine Learning ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Reference serum creatinine levels according to sex, age, and height in children with Down syndrome.
Autorzy :
Nishino T; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan. .; Department of Pediatrics, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. .
Endo S; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Miyano H; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Takemasa Y; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Saito M; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Umeda C; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Tomii Y; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Watanabe Y; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Nakagawa M; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Kakegawa D; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
Fujinaga S; Division of Nephrology, Saitama Children's Medical Center, 1-2 Shintoshin, Chuo-ku, Saitama-City, Saitama, 330 8777, Japan.
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Źródło :
European journal of pediatrics [Eur J Pediatr] 2021 Sep; Vol. 180 (9), pp. 2977-2983. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*
Body Height ; Child ; Creatinine ; Female ; Glomerular Filtration Rate ; Humans ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Low-grade glioma with novel mutations in KRAS and PMS2 in an adolescent with Down syndrome.
Autorzy :
Adams JW; Neurosciences, University of California San Diego, La Jolla, California, USA.
Malicki D; Pathology, Rady Children's Hospital University of California San Diego, San Diego, California, USA.
Levy M; Neurosurgery, University of California San Diego, San Diego, California, USA.
Crawford JR; Neurosciences and Pediatrics, University of California San Diego, San Diego, California, USA .
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Aug 10; Vol. 14 (8). Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Brain Neoplasms*/genetics
Down Syndrome*/complications
Down Syndrome*/genetics
Glioma*/genetics
Adolescent ; Humans ; Mismatch Repair Endonuclease PMS2/genetics ; Mutation ; Proto-Oncogene Proteins p21(ras)/genetics
Czasopismo naukowe
Tytuł :
Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study.
Autorzy :
Fagan AM; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA. Electronic address: .
Henson RL; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Li Y; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Boerwinkle AH; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Xiong C; Division of Biostatistics, Washington University School of Medicine, St Louis, MO, USA.
Bateman RJ; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Goate A; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ances BM; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.
Doran E; Department of Pediatrics, UC Irvine School of Medicine, Irvine, CA, USA.
Christian BT; Department of Medical Physics, Waisman Center, University of Wisconsin-Madison, Madison, WI, USA; Department of Psychiatry, Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Lai F; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Rosas HD; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Schupf N; Department of Epidemiology, Columbia University Irving Medical Center, New York, NY, USA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Krinsky-McHale S; New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
Silverman W; Department of Pediatrics, UC Irvine School of Medicine, Irvine, CA, USA.
Lee JH; Department of Epidemiology, Columbia University Irving Medical Center, New York, NY, USA; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Klunk WE; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Allegri RF; Department of Cognitive Neurology, Instituto Neurologico Fleni, Buenos Aires, Argentina.
Chhatwal JP; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Day GS; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA.
Graff-Radford NR; Department of Neurology, Mayo Clinic Florida, Jacksonville, FL, USA.
Jucker M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases, Tübingen, Germany.
Levin J; Department of Neurology, Ludwig-Maximilians-Universität München, German Center for Neurodegenerative Diseases, Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Martins RN; School of Medical Health and Sciences, Edith Cowan University, Joondalup, WA, Australia.
Masters CL; Florey Institute, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia.
Mori H; Department of Clinical Neuroscience, Osaka City University Medical School, Abenoku, Osaka, Japan.
Mummery CJ; Dementia Research Centre, Institute of Neurology, University College London, London, UK.
Niimi Y; Unit for Early and Exploratory Clinical Development, University of Tokyo, Tokyo, Japan.
Ringman JM; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Salloway S; Memory and Aging Program, Brown University, Butler Hospital, Providence, RI, USA.
Schofield PR; Neuroscience Research Australia, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
Shoji M; Geriatrics Research Institute and Hospital, Maebashi, Gunma, Japan.
Lott IT; Department of Pediatrics, UC Irvine School of Medicine, Irvine, CA, USA.
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Corporate Authors :
Alzheimer's Biomarker Consortium–Down Syndrome
Dominantly Inherited Alzheimer Network
Źródło :
The Lancet. Neurology [Lancet Neurol] 2021 Aug; Vol. 20 (8), pp. 615-626.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*cerebrospinal fluid
Down Syndrome/*cerebrospinal fluid
Adult ; Alzheimer Disease/diagnosis ; Alzheimer Disease/genetics ; Amyloid beta-Peptides/cerebrospinal fluid ; Apolipoproteins E/genetics ; Biomarkers/cerebrospinal fluid ; Cross-Sectional Studies ; Down Syndrome/diagnosis ; Down Syndrome/genetics ; Encephalitis/cerebrospinal fluid ; Female ; Genotype ; Gliosis/cerebrospinal fluid ; Heterozygote ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Neurofilament Proteins/cerebrospinal fluid ; Peptide Fragments/cerebrospinal fluid ; tau Proteins/cerebrospinal fluid
Czasopismo naukowe
Tytuł :
Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study.
Autorzy :
Carmona-Iragui M; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain; Horizon 21 Consortium, Paris, France. Electronic address: .
Alcolea D; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain.
Barroeta I; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain; Horizon 21 Consortium, Paris, France.
Videla L; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain; Horizon 21 Consortium, Paris, France.
Muñoz L; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain.
Van Pelt KL; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
Schmitt FA; Department of Neurology, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
Lightner DD; Department of Neurology, University of Kentucky, Lexington, KY, USA.
Koehl LM; Department of Neurology, University of Kentucky, Lexington, KY, USA.
Jicha G; Department of Neurology, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
Sacco S; Horizon 21 Consortium, Paris, France; Institut Jérôme Lejeune, Paris, France.
Mircher C; Institut Jérôme Lejeune, Paris, France.
Pape SE; Horizon 21 Consortium, Paris, France; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; South London and the Maudsley Foundation NHS Trust, London, UK; The LonDownS consortium, London, UK.
Hithersay R; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; The LonDownS consortium, London, UK.
Clare ICH; Department of Psychiatry, University of Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK; National Institute of Health Research, Applied Research Collaboration, East of England, Cambridge, UK.
Holland AJ; Department of Psychiatry, University of Cambridge, UK.
Nübling G; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany.
Levin J; Horizon 21 Consortium, Paris, France; Department of Neurology, Ludwig-Maximilians-Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany.
Zaman SH; Horizon 21 Consortium, Paris, France; Department of Psychiatry, University of Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.
Strydom A; Horizon 21 Consortium, Paris, France; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; South London and the Maudsley Foundation NHS Trust, London, UK; The LonDownS consortium, London, UK.
Rebillat AS; Horizon 21 Consortium, Paris, France; Institut Jérôme Lejeune, Paris, France.
Head E; Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, USA.
Blesa R; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain.
Lleó A; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain.
Fortea J; Sant Pau Memory Unit, Neurology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Madrid, Spain; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain; Horizon 21 Consortium, Paris, France. Electronic address: .
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Źródło :
The Lancet. Neurology [Lancet Neurol] 2021 Aug; Vol. 20 (8), pp. 605-614.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Down Syndrome/*diagnosis
Neurofilament Proteins/*blood
Adult ; Age Factors ; Aged ; Alzheimer Disease/blood ; Alzheimer Disease/etiology ; Apolipoprotein E4/genetics ; Cohort Studies ; Disease Progression ; Down Syndrome/blood ; Down Syndrome/psychology ; Female ; Humans ; Intellectual Disability ; Intermediate Filaments ; Longitudinal Studies ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; ROC Curve ; Sex Factors
Czasopismo naukowe
Tytuł :
High-resolution functional connectivity of the default mode network in young adults with down syndrome.
Autorzy :
Koenig KA; Imaging Sciences, Imaging Institute, Cleveland Clinic, 9500 Euclid Ave / U15, Cleveland, OH, 44195, USA. .
Bekris LM; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Ruedrich S; Department of Psychiatry, University Hospitals, Cleveland, OH, USA.
Weber GE; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Khrestian M; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Oh SH; Imaging Sciences, Imaging Institute, Cleveland Clinic, 9500 Euclid Ave / U15, Cleveland, OH, 44195, USA.; Department of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Republic of Korea.
Kim S; Imaging Sciences, Imaging Institute, Cleveland Clinic, 9500 Euclid Ave / U15, Cleveland, OH, 44195, USA.
Wang ZI; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Leverenz JB; Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
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Źródło :
Brain imaging and behavior [Brain Imaging Behav] 2021 Aug; Vol. 15 (4), pp. 2051-2060. Date of Electronic Publication: 2020 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*/diagnostic imaging
Down Syndrome*/diagnostic imaging
Brain/diagnostic imaging ; Brain Mapping ; Default Mode Network ; Humans ; Magnetic Resonance Imaging ; Young Adult
Czasopismo naukowe
Tytuł :
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer's disease in adults with Down syndrome.
Autorzy :
Lleó A; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. .; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. .
Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; UK Dementia Research Institute at UCL, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
Pegueroles J; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Karikari TK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.
Carmona-Iragui M; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain.
Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation, London, UK.
Montal V; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Barroeta I; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Lantero-Rodríguez J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.
Videla L; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain.
Altuna M; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Benejam B; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain.
Fernandez S; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain.
Valldeneu S; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Garzón D; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Bejanin A; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Iulita MF; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Camacho V; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Medrano-Martorell S; Hospital del Mar-Universitat Autònoma Barcelona (UAB), Barcelona, Spain.
Belbin O; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Clarimon J; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Lehmann S; The Institute for Neurosciences of Montpellier, Université de Montpellier, Centre Hospitalier Universitaire de Montpellier, INSERM, Montpellier, France.
Alcolea D; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Blesa R; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Möndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Fortea J; Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. .; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. .; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 14; Vol. 12 (1), pp. 4304. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*diagnosis
Down Syndrome/*diagnosis
tau Proteins/*blood
Adult ; Alzheimer Disease/blood ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Area Under Curve ; Atrophy ; Biomarkers/blood ; Biomarkers/metabolism ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Cognition ; Cross-Sectional Studies ; Disease Progression ; Down Syndrome/blood ; Down Syndrome/pathology ; Female ; Humans ; Male ; Middle Aged ; Neurofilament Proteins/blood ; Phosphorylation ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Effectiveness of Swimming Program in Adolescents with Down Syndrome.
Autorzy :
Naczk A; Department of Physical Education and Sport, Faculty of Physical Culture in Gorzow Wielkopolski, University School of Physical Education in Poznan, 66-400 Gorzow Wielkopolski, Poland.
Gajewska E; Department of Developmental Neurology, Poznan University of Medical Sciences, 60-355 Poznan, Poland.
Naczk M; Institute of Health Sciences, Collegium Medicum, University of Zielona Gora, 65-417 Zielona Gora, Poland.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Jul 12; Vol. 18 (14). Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Down Syndrome*/therapy
Swimming*
Adolescent ; Body Composition ; Exercise Therapy ; Humans ; Muscle Strength
Czasopismo naukowe
Tytuł :
Cerebral venous thrombosis in a patient with Down syndrome and coronavirus disease 2019: a case report.
Autorzy :
Robayo-Amortegui H; Critical Medicine and Intensive Care Resident, Universidad de la SabanaFundación Clínica Shaio, Bogotá, Colombia.
Valenzuela-Faccini N; Critical Medicine and Intensive Care Resident, Universidad de la SabanaFundación Clínica Shaio, Bogotá, Colombia.
Quecano-Rosas C; Critical Medicine and Intensive Care Resident, Universidad de la SabanaFundación Clínica Shaio, Bogotá, Colombia.
Zabala-Muñoz D; Critical Medicine and Intensive Care Resident, Universidad de la SabanaFundación Clínica Shaio, Bogotá, Colombia.
Perez-Garzon M; Intensive Care Specialist, Fundación Clínica Shaio, Bogotá, Colombia. .
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 Jul 12; Vol. 15 (1), pp. 364. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
COVID-19*
Down Syndrome*/complications
Venous Thrombosis*
Female ; Humans ; Pandemics ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Impact of two different pulmonary rehabilitation methods in children with down syndrome.
Autorzy :
Mohamed RA; Department of Physical Therapy for Growth and Developmental Disorders in Children and Its Surgery, Faculty of Physical Therapy, Cairo University, Egypt. Electronic address: .
Mohamed ESH; Cardiopulmonary Disorders, Physical Therapy Department, Buraydah Private Colleges, Saudi Arabia. Electronic address: .
Habshy SM; Cardiopulmonary Disorders, Physical Therapy Department, Abu-Reesh Mounira Hospitals, Cairo, Egypt. Electronic address: .
Aly SM; Department of Biomechanics, Faculty of Physical Therapy, Cairo University, Egypt. Electronic address: .
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Źródło :
Journal of bodywork and movement therapies [J Bodyw Mov Ther] 2021 Jul; Vol. 27, pp. 512-521. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*
Muscle Stretching Exercises*
Adolescent ; Breathing Exercises ; Child ; Humans ; Muscle Strength ; Respiratory Muscles
Czasopismo naukowe
Tytuł :
Application of Multiple Short Tandem Repeat Loci for Rapid Diagnosis of Down Syndrome and Edward Syndrome.
Autorzy :
Wang K
Lai L
Tu H
Lin H
Shen X
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Źródło :
Clinical laboratory [Clin Lab] 2021 Jul 01; Vol. 67 (7).
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*/diagnosis
Down Syndrome*/genetics
Aneuploidy ; Female ; Humans ; Microsatellite Repeats ; Polymerase Chain Reaction ; Pregnancy ; Trisomy ; Trisomy 18 Syndrome
Czasopismo naukowe
Tytuł :
Adenovirus Infection in Children with Down Syndrome.
Autorzy :
Dotan M; Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Zion E; Department of Pediatrics A, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ben-Zvi H; Department of Clinical Microbiology, Rabin Medical Center (Beillinson Campus), Petah Tikva, Israel.
Yarden-Bilavsky H; Department of Pediatrics A, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Bilavsky E; Department of Pediatrics C, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2021 Jul; Vol. 23 (7), pp. 416-419.
Typ publikacji :
Journal Article
MeSH Terms :
Adenovirus Infections, Human*/complications
Adenovirus Infections, Human*/diagnosis
Adenovirus Infections, Human*/epidemiology
Adenovirus Infections, Human*/physiopathology
Critical Care*/methods
Critical Care*/statistics & numerical data
Down Syndrome*/epidemiology
Down Syndrome*/physiopathology
Down Syndrome*/virology
Hospitalization/*statistics & numerical data
Length of Stay/*statistics & numerical data
Adenoviridae/isolation & purification ; Child, Preschool ; Female ; Hospitals, Pediatric ; Humans ; Incidence ; Israel/epidemiology ; Male ; Risk Assessment ; Severity of Illness Index ; Tertiary Care Centers/statistics & numerical data
Czasopismo naukowe
Tytuł :
Exploring different aspects of emotion understanding in adults with Down Syndrome.
Autorzy :
Andrés-Roqueta C; Department of Developmental, Educational and Social Psychology and Methodology, Universitat Jaume I de Castelló, Av. Vicent Sos Baynat, s/n, 12071 Castelló de la Plana, Spain. Electronic address: .
Soria-Izquierdo E; Department of Developmental, Educational and Social Psychology and Methodology, Universitat Jaume I de Castelló, Av. Vicent Sos Baynat, s/n, 12071 Castelló de la Plana, Spain. Electronic address: .
Górriz-Plumed AB; Department of Developmental, Educational and Social Psychology and Methodology, Universitat Jaume I de Castelló, Av. Vicent Sos Baynat, s/n, 12071 Castelló de la Plana, Spain. Electronic address: .
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Źródło :
Research in developmental disabilities [Res Dev Disabil] 2021 Jul; Vol. 114, pp. 103962. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article
MeSH Terms :
Down Syndrome*
Language Development Disorders*
Adult ; Child ; Emotions ; Humans ; Memory, Short-Term ; Vocabulary
Czasopismo naukowe

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