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Wyszukujesz frazę ""Dravid, Shashank M."" wg kryterium: Autor


Tytuł :
Ultrastructural localization of glutamate delta 1 (GluD1) receptor immunoreactivity in the mouse and monkey striatum.
Autorzy :
Hoover AH; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA.
Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
Dravid SM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
Smith Y; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA.; Department of Neurology, Emory University, Atlanta, Georgia, USA.
Villalba RM; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA.
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Źródło :
The Journal of comparative neurology [J Comp Neurol] 2020 Oct 08. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture.
Autorzy :
Hu G; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. .
Niu F; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA.
Liao K; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA.
Periyasamy P; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA.
Sil S; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA.
Liu J; Department of Pharmacology, Creighton University, Omaha, NE, USA.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, USA.
Buch S; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. .
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Źródło :
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2020 Sep; Vol. 15 (3), pp. 538-553. Date of Electronic Publication: 2019 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Antipsychotic-like profile of CIQ isomers in animal models of schizophrenia.
Autorzy :
Gawai P; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Upadhyay R; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Gakare SG; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Sarode L; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, Nebraska, USA.
Ugale RR; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
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Źródło :
Behavioural pharmacology [Behav Pharmacol] 2020 Sep; Vol. 31 (6), pp. 524-534.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats.
Autorzy :
Stairs DJ; Creighton University Department of Psychological Science, United States of America. Electronic address: .
Chacho NM; Creighton University Department of Psychological Science, United States of America.
Wunsch C; Creighton University Department of Psychological Science, United States of America.
Pipitone L; Creighton University Department of Psychological Science, United States of America.
Dravid SM; Creighton University Department of Pharmacology and Neuroscience, United States of America.
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Źródło :
Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2020 Sep; Vol. 196, pp. 172979. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity.
Autorzy :
Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Gandhi PJ; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Gawande DY; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Hoover A; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA.
Villalba RM; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA.
Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Smith Y; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA; Dept. Neurology, Emory University, Atlanta, GA 30329, USA.
Dravid SM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Electronic address: .
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Źródło :
Neurobiology of disease [Neurobiol Dis] 2020 Apr; Vol. 137, pp. 104746. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Behavior, Animal/*physiology
Corpus Striatum/*metabolism
Receptors, Glutamate/*metabolism
Thalamus/*metabolism
Animals ; Corpus Striatum/physiology ; Female ; Male ; Mice ; Neurogenesis/physiology ; Synapses/physiology ; Synaptic Transmission/physiology ; Thalamus/physiopathology
Czasopismo naukowe
Tytuł :
Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.
Autorzy :
Shelkar GP; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Pavuluri R; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Gandhi PJ; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Ravikrishnan A; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Gawande DY; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Liu J; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Stairs DJ; Psychology, Creighton University, Omaha, NE, 68178, USA.
Ugale RR; Department of Pharmaceutical Sciences, R.T.M. Nagpur University, Nagpur, Maharashtra, 440033, India.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. .
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Źródło :
Scientific reports [Sci Rep] 2019 May 20; Vol. 9 (1), pp. 7572. Date of Electronic Publication: 2019 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Gene Deletion*
Receptors, N-Methyl-D-Aspartate/*genetics
Schizophrenia/*genetics
Animals ; Anxiety/genetics ; Depression/genetics ; Disease Models, Animal ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Schizophrenia/chemically induced
Czasopismo naukowe
Tytuł :
A mouse model of seizures in anti-N-methyl-d-aspartate receptor encephalitis.
Autorzy :
Taraschenko O; Division of Epilepsy, Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska.
Fox HS; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska.
Pittock SJ; Laboratory Medicine and Pathology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Zekeridou A; Laboratory Medicine and Pathology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Gafurova M; College of Arts and Sciences, University of Nebraska Omaha, Omaha, Nebraska.
Eldridge E; Division of Epilepsy, Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska.
Liu J; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Dingledine R; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia.
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Źródło :
Epilepsia [Epilepsia] 2019 Mar; Vol. 60 (3), pp. 452-463. Date of Electronic Publication: 2019 Feb 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Anti-N-Methyl-D-Aspartate Receptor Encephalitis/*complications
Seizures/*etiology
Animals ; Anti-N-Methyl-D-Aspartate Receptor Encephalitis/pathology ; Anti-N-Methyl-D-Aspartate Receptor Encephalitis/physiopathology ; Autoantibodies/pharmacology ; Brain/pathology ; Brain/physiopathology ; Disease Models, Animal ; Electroencephalography ; Male ; Mice ; Mice, Inbred C57BL ; Seizures/pathology ; Seizures/physiopathology
Czasopismo naukowe
Tytuł :
In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.
Autorzy :
Alsaad HA; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA.
DeKorver NW; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA.
Mao Z; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, USA.
Arikkath J; Department of Developmental Neuroscience, Monroe Meyer Institute, University of Nebraska Medical Center, Omaha, NE, USA.
Monaghan DT; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA. .
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Źródło :
Neurochemical research [Neurochem Res] 2019 Jan; Vol. 44 (1), pp. 61-77. Date of Electronic Publication: 2018 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Interneurons/*metabolism
Neuroglia/*metabolism
RNA, Messenger/*biosynthesis
Receptors, N-Methyl-D-Aspartate/*biosynthesis
Telencephalon/*metabolism
Animals ; Gene Expression ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Protein Subunits/biosynthesis ; Protein Subunits/genetics ; RNA, Messenger/genetics ; Receptors, N-Methyl-D-Aspartate/genetics
Czasopismo naukowe
Tytuł :
Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens.
Autorzy :
Liu J; Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Gandhi PJ; Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Pavuluri R; Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Shelkar GP; Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
Dravid SM; Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA. .
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Źródło :
Translational psychiatry [Transl Psychiatry] 2018 Oct 12; Vol. 8 (1), pp. 219. Date of Electronic Publication: 2018 Oct 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neuronal Plasticity*
Cocaine/*administration & dosage
Neurons/*physiology
Nucleus Accumbens/*drug effects
Nucleus Accumbens/*physiology
Receptors, Glutamate/*physiology
Animals ; Dendrites/physiology ; Drug-Seeking Behavior ; Excitatory Postsynaptic Potentials ; Male ; Mice, Knockout ; Receptor, Metabotropic Glutamate 5/physiology ; Receptors, Glutamate/genetics ; Receptors, Metabotropic Glutamate/physiology ; Receptors, N-Methyl-D-Aspartate/physiology
Czasopismo naukowe
Tytuł :
Region-specific Expression of NMDA Receptor GluN2C Subunit in Parvalbumin-Positive Neurons and Astrocytes: Analysis of GluN2C Expression using a Novel Reporter Model.
Autorzy :
Ravikrishnan A; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA.
Gandhi PJ; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA.
Shelkar GP; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA.
Liu J; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA.
Pavuluri R; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE 68178, USA. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2018 Jun 01; Vol. 380, pp. 49-62. Date of Electronic Publication: 2018 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Brain/*metabolism
Neurons/*metabolism
Receptors, N-Methyl-D-Aspartate/*biosynthesis
Animals ; Gene Knock-In Techniques/methods ; Green Fluorescent Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Models, Animal ; Parvalbumins/metabolism ; Receptors, N-Methyl-D-Aspartate/analysis
Czasopismo naukowe
Tytuł :
Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives.
Autorzy :
Sapkota K; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA.
Irvine MW; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Fang G; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Burnell ES; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Bannister N; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Volianskis A; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK; Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK.
Culley GR; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, USA.
Collingridge GL; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; Department of Physiology, University of Toronto, Toronto, ON, Canada.
Jane DE; Centre for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.
Monaghan DT; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2017 Oct; Vol. 125, pp. 64-79. Date of Electronic Publication: 2017 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Carboxylic Acids/*pharmacology
Excitatory Amino Acid Agents/*pharmacology
Naphthalenes/*pharmacology
Receptors, N-Methyl-D-Aspartate/*metabolism
Allosteric Regulation ; Animals ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/metabolism ; Dose-Response Relationship, Drug ; Glutamic Acid/pharmacology ; Glycine/pharmacology ; HEK293 Cells ; Humans ; Hydrogen-Ion Concentration ; Mice ; Oocytes ; Patch-Clamp Techniques ; Protein Conformation/drug effects ; Pyramidal Cells/drug effects ; Pyramidal Cells/metabolism ; Receptors, N-Methyl-D-Aspartate/genetics ; Tissue Culture Techniques ; Transfection ; Xenopus laevis
Czasopismo naukowe
Tytuł :
A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors.
Autorzy :
Chopra DA; Department of Pharmacology, Creighton University, Omaha, NE, 68178, United States.
Sapkota K; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, United States.
Irvine MW; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Fang G; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Jane DE; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Monaghan DT; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, United States.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, 68178, United States. .
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Źródło :
Scientific reports [Sci Rep] 2017 Jul 31; Vol. 7 (1), pp. 6933. Date of Electronic Publication: 2017 Jul 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Carboxylic Acids/*pharmacology
Naphthalenes/*pharmacology
Receptors, N-Methyl-D-Aspartate/*chemistry
Receptors, N-Methyl-D-Aspartate/*metabolism
Allosteric Regulation ; Animals ; Binding Sites ; Carboxylic Acids/chemistry ; Drug Synergism ; HEK293 Cells ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Naphthalenes/chemistry ; Patch-Clamp Techniques ; Protein Conformation ; Xenopus
Czasopismo naukowe
Tytuł :
The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function.
Autorzy :
Gupta SC; Department of Pharmacology, Omaha, NE 68178, USA.
Ravikrishnan A; Department of Pharmacology, Omaha, NE 68178, USA.
Liu J; Department of Pharmacology, Omaha, NE 68178, USA.
Mao Z; Department of Pharmacology and Experimental Therapeutics, University of Nebraska-Medical Center, Omaha, NE, 68198, USA.
Pavuluri R; Department of Pharmacology, Omaha, NE 68178, USA.
Hillman BG; Department of Pharmacology, Omaha, NE 68178, USA.
Gandhi PJ; Department of Pharmacology, Omaha, NE 68178, USA.
Stairs DJ; Psychology, Creighton University, Omaha, NE 68178, USA.
Li M; Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Ugale RR; Department of Pharmaceutical Sciences, R.T.M. Nagpur University, Nagpur, Maharashtra 440033, India.
Monaghan DT; Department of Pharmacology and Experimental Therapeutics, University of Nebraska-Medical Center, Omaha, NE, 68198, USA.
Dravid SM; Department of Pharmacology, Omaha, NE 68178, USA.
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Źródło :
Scientific reports [Sci Rep] 2016 Dec 06; Vol. 6, pp. 38321. Date of Electronic Publication: 2016 Dec 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials/*physiology
Cognition/*physiology
Prefrontal Cortex/*metabolism
Pyramidal Cells/*metabolism
Receptors, N-Methyl-D-Aspartate/*genetics
Action Potentials/drug effects ; Animals ; Cognition/drug effects ; Dendritic Spines/drug effects ; Dendritic Spines/metabolism ; Dendritic Spines/ultrastructure ; Dizocilpine Maleate/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Gene Expression Regulation ; Glutamate Decarboxylase/genetics ; Glutamate Decarboxylase/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microtomy ; Parvalbumins/metabolism ; Patch-Clamp Techniques ; Phencyclidine/pharmacology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/pathology ; Prepulse Inhibition/drug effects ; Pyramidal Cells/drug effects ; Pyramidal Cells/pathology ; Receptors, N-Methyl-D-Aspartate/deficiency ; Reflex, Startle/drug effects ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Interactions of nitric oxide with α2 -adrenoceptors within the locus coeruleus underlie the facilitation of inhibitory avoidance memory by agmatine.
Autorzy :
Shelkar GP; Division of Neuroscience, Department of Pharmacology, Shrimati Kishoritai Bhoyar College of Pharmacy, Nagpur, Maharashtra, India.; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Gakare SG; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
Chakraborty S; Division of Neuroscience, Department of Pharmacology, Shrimati Kishoritai Bhoyar College of Pharmacy, Nagpur, Maharashtra, India.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, USA.
Ugale RR; Division of Neuroscience, Department of Pharmacology, Shrimati Kishoritai Bhoyar College of Pharmacy, Nagpur, Maharashtra, India.; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2016 Sep; Vol. 173 (17), pp. 2589-99. Date of Electronic Publication: 2016 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Agmatine/*pharmacology
Avoidance Learning/*drug effects
Locus Coeruleus/*drug effects
Locus Coeruleus/*metabolism
Nitric Oxide/*metabolism
Receptors, Adrenergic, alpha-2/*metabolism
Agmatine/administration & dosage ; Animals ; Dose-Response Relationship, Drug ; Male ; Nitric Oxide/chemistry ; Rats ; Rats, Wistar ; Receptors, Adrenergic, alpha-2/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus.
Autorzy :
Suryavanshi PS; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Gupta SC; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Yadav R; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Kesherwani V; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Liu J; Department of Pharmacology, Creighton University, Omaha, Nebraska.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, Nebraska .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2016 Aug; Vol. 90 (2), pp. 96-105. Date of Electronic Publication: 2016 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Hippocampus/*metabolism
Receptor, Metabotropic Glutamate 5/*metabolism
Receptors, Glutamate/*metabolism
Animals ; Gene Deletion ; Immunoprecipitation ; Mice, Knockout ; Models, Biological ; Phosphorylation ; Protein Binding ; Protein Isoforms/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Metabotropic Glutamate/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Essential Roles for ARID1B in Dendritic Arborization and Spine Morphology of Developing Pyramidal Neurons.
Autorzy :
Ka M; Department of Developmental Neuroscience, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198, and.
Chopra DA; Department of Pharmacology, Creighton University, Omaha, Nebraska 68178.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, Nebraska 68178.
Kim WY; Department of Developmental Neuroscience, Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha, Nebraska 68198, and .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2016 Mar 02; Vol. 36 (9), pp. 2723-42.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dendritic Spines*
Brain/*cytology
Brain/*growth & development
DNA-Binding Proteins/*metabolism
Neuronal Plasticity/*genetics
Pyramidal Cells/*cytology
Transcription Factors/*metabolism
Action Potentials/drug effects ; Action Potentials/genetics ; Animals ; Animals, Newborn ; Cells, Cultured ; DNA-Binding Proteins/genetics ; Embryo, Mammalian ; Female ; Gene Expression Regulation, Developmental/genetics ; Glial Fibrillary Acidic Protein/metabolism ; Humans ; Mice ; Microtubule-Associated Proteins/metabolism ; Nuclear Proteins/metabolism ; Patch-Clamp Techniques ; Pregnancy ; Transcription Factors/genetics ; Vesicular Glutamate Transport Protein 1/metabolism ; Vesicular Inhibitory Amino Acid Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors.
Autorzy :
Kristensen AS; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Hansen KB; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Naur P; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Olsen L; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Kurtkaya NL; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Dravid SM; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Kvist T; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Yi F; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Pøhlsgaard J; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Clausen RP; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Gajhede M; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.).
Kastrup JS; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.) .
Traynelis SF; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (A.S.K., K.B.H., N.L.K., S.M.D., S.F.T.); Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark (A.S.K., P.N., L.O., T.K., J.P., R.P.C., M.G., J.S.K.); and Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (K.B.H., F.Y.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2016 Feb; Vol. 89 (2), pp. 253-62. Date of Electronic Publication: 2015 Dec 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Glutamate/*chemistry
Receptors, Glutamate/*metabolism
Animals ; Binding Sites/physiology ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Female ; Ligands ; Protein Binding/physiology ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Rats ; Serine/chemistry ; Serine/metabolism ; Serine/pharmacology ; Stereoisomerism ; Structure-Activity Relationship ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Bidirectional Effect of Pregnenolone Sulfate on GluN1/GluN2A N-Methyl-D-Aspartate Receptor Gating Depending on Extracellular Calcium and Intracellular Milieu.
Autorzy :
Chopra DA; Department of Pharmacology, Creighton University, Omaha, Nebraska (D.A.C., S.M.D.); and Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska (D.T.M.).
Monaghan DT; Department of Pharmacology, Creighton University, Omaha, Nebraska (D.A.C., S.M.D.); and Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska (D.T.M.).
Dravid SM; Department of Pharmacology, Creighton University, Omaha, Nebraska (D.A.C., S.M.D.); and Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska (D.T.M.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2015 Oct; Vol. 88 (4), pp. 650-9. Date of Electronic Publication: 2015 Jul 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium/*metabolism
Extracellular Fluid/*metabolism
Intracellular Fluid/*metabolism
Nerve Tissue Proteins/*metabolism
Pregnenolone/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Extracellular Fluid/drug effects ; HEK293 Cells ; Humans ; Intracellular Fluid/drug effects ; Ion Channel Gating/drug effects ; Ion Channel Gating/physiology ; Nerve Tissue Proteins/agonists ; Nerve Tissue Proteins/antagonists & inhibitors ; Pregnenolone/pharmacology ; Receptors, N-Methyl-D-Aspartate/agonists ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity.
Autorzy :
Gupta SC; Department of Pharmacology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Yadav R; Department of Pharmacology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Pavuluri R; Department of Pharmacology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Morley BJ; Neurochemistry Laboratory, Boys Town National Research Hospital, 555 North 30th Street, Omaha, NE 68178, USA.
Stairs DJ; Department of Psychology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Dravid SM; Department of Pharmacology, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2015 Jun; Vol. 93, pp. 274-84. Date of Electronic Publication: 2015 Feb 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Cortex/*cytology
Dendritic Spines/*physiology
Hippocampus/*cytology
Neurons/*ultrastructure
Receptors, AMPA/*metabolism
Receptors, Glutamate/*deficiency
Receptors, N-Methyl-D-Aspartate/*metabolism
Animals ; Animals, Newborn ; Cerebral Cortex/growth & development ; Dendritic Spines/ultrastructure ; Desipramine/pharmacology ; Enzyme Inhibitors/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Exploratory Behavior/physiology ; Glutamate Dehydrogenase ; Hippocampus/growth & development ; Mice ; Mice, Knockout ; Motor Activity/drug effects ; Neurons/drug effects ; Neurons/physiology ; Phenols/pharmacology ; Piperidines/pharmacology ; Receptors, Glutamate/genetics ; Serotonin Uptake Inhibitors/pharmacology ; Signal Transduction/drug effects ; Sodium Channel Blockers/pharmacology ; Swimming/psychology ; Tetrodotoxin/pharmacology
Czasopismo naukowe
Tytuł :
Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors.
Autorzy :
Park H
Han KS
Seo J
Lee J
Dravid SM
Woo J
Chun H
Cho S
Bae JY
An H
Koh W
Yoon BE
Berlinguer-Palmini R
Mannaioni G
Traynelis SF
Bae YC
Choi SY
Lee CJ
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Źródło :
Molecular brain [Mol Brain] 2015 Feb 03; Vol. 8, pp. 7. Date of Electronic Publication: 2015 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Neuronal Plasticity*
Astrocytes/*metabolism
Eye Proteins/*metabolism
Glutamic Acid/*metabolism
Hippocampus/*metabolism
Ion Channels/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Animals ; Bestrophins ; CA1 Region, Hippocampal/metabolism ; CA1 Region, Hippocampal/ultrastructure ; Hippocampus/ultrastructure ; Humans ; Long-Term Potentiation ; Mice ; Models, Biological ; Receptor, PAR-1/metabolism ; Synapses/metabolism ; Synaptic Transmission
Czasopismo naukowe

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