Autor: "Dravid, Shashank M." - OpacWWW

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Tytuł :: Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.
Autorzy :: Shelkar GP; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Pavuluri R; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Gandhi PJ; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Ravikrishnan A; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Gawande DY; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Liu J; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA.
Stairs DJ; Psychology, Creighton University, Omaha, NE, 68178, USA.
Ugale RR; Department of Pharmaceutical Sciences, R.T.M. Nagpur University, Nagpur, Maharashtra, 440033, India.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. .; Pokaż więcej
Źródło :: Scientific reports [Sci Rep] 2019 May 20; Vol. 9 (1), pp. 7572. Date of Electronic Publication: 2019 May 20.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Gene Deletion*
Receptors, N-Methyl-D-Aspartate/*genetics
Schizophrenia/*genetics
Animals ; Anxiety/genetics ; Depression/genetics ; Disease Models, Animal ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Schizophrenia/chemically induced
: Czasopismo naukowe

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Tytuł :: A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors.
Autorzy :: Chopra DA; Department of Pharmacology, Creighton University, Omaha, NE, 68178, United States.
Sapkota K; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, United States.
Irvine MW; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Fang G; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Jane DE; School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, UK.
Monaghan DT; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, United States.
Dravid SM; Department of Pharmacology, Creighton University, Omaha, NE, 68178, United States. .; Pokaż więcej
Źródło :: Scientific reports [Sci Rep] 2017 Jul 31; Vol. 7 (1), pp. 6933. Date of Electronic Publication: 2017 Jul 31.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Carboxylic Acids/*pharmacology
Naphthalenes/*pharmacology
Receptors, N-Methyl-D-Aspartate/*chemistry
Receptors, N-Methyl-D-Aspartate/*metabolism
Allosteric Regulation ; Animals ; Binding Sites ; Carboxylic Acids/chemistry ; Drug Synergism ; HEK293 Cells ; Humans ; Models, Molecular ; Molecular Docking Simulation ; Naphthalenes/chemistry ; Patch-Clamp Techniques ; Protein Conformation ; Xenopus
: Czasopismo naukowe

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Tytuł :: The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function.
Autorzy :: Gupta SC; Department of Pharmacology, Omaha, NE 68178, USA.
Ravikrishnan A; Department of Pharmacology, Omaha, NE 68178, USA.
Liu J; Department of Pharmacology, Omaha, NE 68178, USA.
Mao Z; Department of Pharmacology and Experimental Therapeutics, University of Nebraska-Medical Center, Omaha, NE, 68198, USA.
Pavuluri R; Department of Pharmacology, Omaha, NE 68178, USA.
Hillman BG; Department of Pharmacology, Omaha, NE 68178, USA.
Gandhi PJ; Department of Pharmacology, Omaha, NE 68178, USA.
Stairs DJ; Psychology, Creighton University, Omaha, NE 68178, USA.
Li M; Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Ugale RR; Department of Pharmaceutical Sciences, R.T.M. Nagpur University, Nagpur, Maharashtra 440033, India.
Monaghan DT; Department of Pharmacology and Experimental Therapeutics, University of Nebraska-Medical Center, Omaha, NE, 68198, USA.
Dravid SM; Department of Pharmacology, Omaha, NE 68178, USA.; Pokaż więcej
Źródło :: Scientific reports [Sci Rep] 2016 Dec 06; Vol. 6, pp. 38321. Date of Electronic Publication: 2016 Dec 06.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Action Potentials/*physiology
Cognition/*physiology
Prefrontal Cortex/*metabolism
Pyramidal Cells/*metabolism
Receptors, N-Methyl-D-Aspartate/*genetics
Action Potentials/drug effects ; Animals ; Cognition/drug effects ; Dendritic Spines/drug effects ; Dendritic Spines/metabolism ; Dendritic Spines/ultrastructure ; Dizocilpine Maleate/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Gene Expression Regulation ; Glutamate Decarboxylase/genetics ; Glutamate Decarboxylase/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microtomy ; Parvalbumins/metabolism ; Patch-Clamp Techniques ; Phencyclidine/pharmacology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/pathology ; Prepulse Inhibition/drug effects ; Pyramidal Cells/drug effects ; Pyramidal Cells/pathology ; Receptors, N-Methyl-D-Aspartate/deficiency ; Reflex, Startle/drug effects ; Tissue Culture Techniques
: Czasopismo naukowe

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