Intravenous recombinant cerebellin 1 treatment restores signalling by spinal glutamate delta 1 receptors and mitigates chronic pain.
Autorzy:
Sabnis SS; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. S Narasimhan KK; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. Chettiar PB; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. Gakare SG; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. Asati DG; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. Thakur SS; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University, Omaha, Nebraska, USA.
Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions.
Autorzy:
Gakare SG; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE, United States of America. Bhatt JM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE, United States of America. Narasimhan KKS; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE, United States of America. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Nov 20; Vol. 18 (11), pp. e0294583. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).
GluN2D Subunit in Parvalbumin Interneurons Regulates Prefrontal Cortex Feedforward Inhibitory Circuit and Molecular Networks Relevant to Schizophrenia.
Autorzy:
Gawande DY; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. S Narasimhan KK; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. Electronic address: . Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. Stessman HAF; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska. Electronic address: .
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Źródło:
Biological psychiatry [Biol Psychiatry] 2023 Aug 15; Vol. 94 (4), pp. 297-309. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
GluN2D subunit-containing NMDA receptors regulate reticular thalamic neuron function and seizure susceptibility.
Autorzy:
Gawande DY; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Electronic address: . Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Narasimhan KKS; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Liu J; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Jun 01; Vol. 181, pp. 106117. Date of Electronic Publication: 2023 Apr 07.
Stimulation of Neurite Outgrowth in Cerebrocortical Neurons by Sodium Channel Activator Brevetoxin-2 Requires Both N-Methyl-D-aspartate Receptor 2B (GluN2B) and p21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1).
Autorzy:
Mehrotra S; Department of Pharmacology and Neuroscience, School of Medicine, Creighton University, Omaha, NE 68178, USA.; Omeros, Seattle, WA 98119, USA. Pierce ML; Department of Pharmacology and Neuroscience, School of Medicine, Creighton University, Omaha, NE 68178, USA.; Department of Pharmacology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA. DravidSM; Department of Pharmacology and Neuroscience, School of Medicine, Creighton University, Omaha, NE 68178, USA. Murray TF; Department of Pharmacology and Neuroscience, School of Medicine, Creighton University, Omaha, NE 68178, USA.
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Źródło:
Marine drugs [Mar Drugs] 2022 Aug 31; Vol. 20 (9). Date of Electronic Publication: 2022 Aug 31.
Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.
Autorzy:
Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, USA. Gandhi PJ; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, USA. Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, USA.
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Science advances [Sci Adv] 2022 Jul 22; Vol. 8 (29), pp. eabo6574. Date of Electronic Publication: 2022 Jul 22.
Astrocytic NMDA Receptors in the Basolateral Amygdala Contribute to Facilitation of Fear Extinction.
Autorzy:
Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA. Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA.
Dysfunction of Glutamate Delta-1 Receptor-Cerebellin 1 Trans-Synaptic Signaling in the Central Amygdala in Chronic Pain.
Autorzy:
Gandhi PJ; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Gawande DY; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Gakare SG; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Kiritoshi T; Department of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Ji G; Department of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Misra B; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Neugebauer V; Department of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
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Źródło:
Cells [Cells] 2021 Oct 03; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.
Autorzy:
Gawande DY; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. Liu J; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. Ayala AD; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. Choi D; Yerkes National Primate Research Center, Atlanta, GA, 30329, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA, 30329, USA. Smith Y; Yerkes National Primate Research Center, Atlanta, GA, 30329, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA, 30329, USA.; Department of Neurology, Emory University, Atlanta, GA, 30329, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University, 2500 California Plaza, Omaha, NE, USA. .
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Źródło:
Molecular neurobiology [Mol Neurobiol] 2021 Oct; Vol. 58 (10), pp. 4787-4801. Date of Electronic Publication: 2021 Jun 26.
Correction to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors.
Autorzy:
Park H; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea. Han KS; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea.; Neuroscience Program, University of Science and Technology (UST), Daejeon, Korea. Seo J; Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. Lee J; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea. DravidSM; Department of Pharmacology, Creighton University, Omaha, NE, USA. Woo J; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea.; Neuroscience Program, University of Science and Technology (UST), Daejeon, Korea. Chun H; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea. Cho S; Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. Bae JY; Department of Oral Anatomy and Neurobiology, School of Dentistry, Kyungpook National University, Daegu, Korea. An H; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea. Koh W; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea.; Neuroscience Program, University of Science and Technology (UST), Daejeon, Korea. Yoon BE; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea.; Department of Nanobiomedical Science, Dankook University, Cheonan, Korea. Berlinguer-Palmini R; School of Electrical and Electronic Engineering, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK. Mannaioni G; Department of Pharmacology, University of Florence, Florence, Italy. Traynelis SF; Department of Pharmacology, Emory University, Atlanta, GA, USA. Bae YC; Department of Oral Anatomy and Neurobiology, School of Dentistry, Kyungpook National University, Daegu, Korea. Choi SY; Department of Physiology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea. . Lee CJ; Center for Neural Science, Korea Institute of Science and Technology (KIST), Seoul, Korea. .; Neuroscience Program, University of Science and Technology (UST), Daejeon, Korea. .; KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea. .
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Źródło:
Molecular brain [Mol Brain] 2021 Jun 29; Vol. 14 (1), pp. 103. Date of Electronic Publication: 2021 Jun 29.
Ultrastructural localization of glutamate delta 1 (GluD1) receptor immunoreactivity in the mouse and monkey striatum.
Autorzy:
Hoover AH; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA. Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, Nebraska, USA. Smith Y; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA.; Department of Neurology, Emory University, Atlanta, Georgia, USA. Villalba RM; Yerkes National Primate Research Center, Atlanta, Georgia, USA.; UDALL Center of Excellence for Parkinson's Disease, Atlanta, Georgia, USA.
Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.
Autorzy:
Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, United States of America. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, United States of America. Sarode LP; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra 440033, India. Gawande DY; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, United States of America. Zhao F; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. Clausen RP; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. Ugale RR; Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra 440033, India. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, United States of America. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2021 Mar; Vol. 150, pp. 105254. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats.
Autorzy:
Stairs DJ; Creighton University Department of Psychological Science, United States of America. Electronic address: . Chacho NM; Creighton University Department of Psychological Science, United States of America. Wunsch C; Creighton University Department of Psychological Science, United States of America. Pipitone L; Creighton University Department of Psychological Science, United States of America. DravidSM; Creighton University Department of Pharmacology and Neuroscience, United States of America.
Hu G; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. . Niu F; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. Liao K; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. Periyasamy P; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. Sil S; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. Liu J; Department of Pharmacology, Creighton University, Omaha, NE, USA. DravidSM; Department of Pharmacology, Creighton University, Omaha, NE, USA. Buch S; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. .
Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity.
Autorzy:
Liu J; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Shelkar GP; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Gandhi PJ; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Gawande DY; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Hoover A; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA. Villalba RM; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA. Pavuluri R; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Smith Y; Yerkes National Primate Research Center, Atlanta, GA 30329, USA; UDALL Center of Excellence for Parkinson's Disease, Atlanta, GA 30329, USA; Dept. Neurology, Emory University, Atlanta, GA 30329, USA. DravidSM; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2020 Apr; Vol. 137, pp. 104746. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.
Autorzy:
Shelkar GP; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Pavuluri R; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Gandhi PJ; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Ravikrishnan A; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Gawande DY; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Liu J; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. Stairs DJ; Psychology, Creighton University, Omaha, NE, 68178, USA. Ugale RR; Department of Pharmaceutical Sciences, R.T.M. Nagpur University, Nagpur, Maharashtra, 440033, India. DravidSM; Department of Pharmacology, Creighton University, Omaha, NE, 68178, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 May 20; Vol. 9 (1), pp. 7572. Date of Electronic Publication: 2019 May 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
A mouse model of seizures in anti-N-methyl-d-aspartate receptor encephalitis.
Autorzy:
Taraschenko O; Division of Epilepsy, Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska. Fox HS; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska. Pittock SJ; Laboratory Medicine and Pathology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota. Zekeridou A; Laboratory Medicine and Pathology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota. Gafurova M; College of Arts and Sciences, University of Nebraska Omaha, Omaha, Nebraska. Eldridge E; Division of Epilepsy, Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, Nebraska. Liu J; Department of Pharmacology, Creighton University, Omaha, Nebraska. DravidSM; Department of Pharmacology, Creighton University, Omaha, Nebraska. Dingledine R; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia.
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Źródło:
Epilepsia [Epilepsia] 2019 Mar; Vol. 60 (3), pp. 452-463. Date of Electronic Publication: 2019 Feb 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.
Autorzy:
Alsaad HA; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA. DeKorver NW; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA. Mao Z; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA. DravidSM; Department of Pharmacology, Creighton University, Omaha, NE, USA. Arikkath J; Department of Developmental Neuroscience, Monroe Meyer Institute, University of Nebraska Medical Center, Omaha, NE, USA. Monaghan DT; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA. .
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Źródło:
Neurochemical research [Neurochem Res] 2019 Jan; Vol. 44 (1), pp. 61-77. Date of Electronic Publication: 2018 Apr 12.
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