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Wyświetlanie 1-20 z 27
Tytuł:
A year in review: brain barriers and brain fluids research in 2022.
Autorzy:
Keep RF; Department of Neurosurgery, University of Michigan, R5018 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. .
Jones HC; Bicester, OX26 1UF, UK.
Hamilton MG; Department of Clinical Neurosciences, Division of Neurosurgery, University of Calgary, Alberta, Canada.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Apr 21; Vol. 20 (1), pp. 30. Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:
Editorial
MeSH Terms:
Blood-Brain Barrier*
Brain*
Choroid Plexus ; Cerebrospinal Fluid
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic disorders and genetic manipulation at the blood-brain barriers.
Autorzy:
Keep RF; Department of Neurosurgery, University of Michigan, R5018 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. .
Jones HC; Gagle Brook House, Bicester, UK.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 Apr 20; Vol. 20 (1), pp. 29. Date of Electronic Publication: 2023 Apr 20.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Blood-Brain Barrier*
Brain*
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Advances in brain barriers and brain fluids research in 2021: great progress in a time of adversity.
Autorzy:
Keep RF; Department of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. .
Jones HC; Bicester, UK.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2022 Jun 09; Vol. 19 (1), pp. 48. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Editorial
MeSH Terms:
Brain*
Nervous System Diseases*
Biological Transport ; Blood-Brain Barrier ; Humans
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brain Barriers and brain fluids research in 2020 and the fluids and barriers of the CNS thematic series on advances in in vitro modeling of the blood-brain barrier and neurovascular unit.
Autorzy:
Keep RF; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, 48105, USA. .; Department of Neurosurgery, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, R5018 BSRB, MI, 48109-2200, USA. .
Jones HC; Gagle Brook House, Chesterton, Bicester, OX26 1UF, UK.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2021 May 21; Vol. 18 (1), pp. 24. Date of Electronic Publication: 2021 May 21.
Typ publikacji:
Editorial
MeSH Terms:
Biomedical Research/*trends
Blood-Brain Barrier/*metabolism
Brain/*metabolism
Choroid Plexus/*metabolism
Glymphatic System/*metabolism
Neurovascular Coupling/*physiology
Animals ; Blood-Brain Barrier/pathology ; Brain/pathology ; Central Nervous System/metabolism ; Central Nervous System/pathology ; Choroid Plexus/pathology ; Glymphatic System/pathology ; Humans ; Hydrocephalus/metabolism ; Hydrocephalus/pathology ; Hydrocephalus/psychology ; Mental Disorders/metabolism ; Mental Disorders/pathology ; Mental Disorders/psychology
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors.
Autorzy:
Griffith JI; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455, USA.
Rathi S; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455, USA.
Zhang W; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455, USA.
Zhang W; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455, USA.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School-Duluth, Duluth, MN 55812, USA.
Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55902, USA.
Elmquist WF; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Dec 11; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 11.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.
Autorzy:
Khammanivong A; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.
Saha J; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.
Spartz AK; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Sorenson BS; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.
Bush AG; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.
Korpela DM; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.
Gopalakrishnan R; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Jonnalagadda S; Department of Chemistry and Biochemistry, University of Minnesota, Duluth, Minnesota.
Mereddy VR; Department of Chemistry and Biochemistry, University of Minnesota, Duluth, Minnesota.
O'Brien TD; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota.
Drewes LR; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, Minnesota.
Dickerson EB; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, Minnesota.
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Źródło:
Veterinary and comparative oncology [Vet Comp Oncol] 2020 Sep; Vol. 18 (3), pp. 324-341. Date of Electronic Publication: 2019 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Cat Diseases/*drug therapy
Mitochondrial Proteins/*pharmacology
Monocarboxylic Acid Transporters/*pharmacology
Mouth Neoplasms/*veterinary
Squamous Cell Carcinoma of Head and Neck/*veterinary
Amino Acid Transport Systems, Neutral/genetics ; Amino Acid Transport Systems, Neutral/pharmacology ; Animals ; Cats ; Cell Line, Tumor ; Humans ; Mitochondria/drug effects ; Mitochondrial Proteins/genetics ; Monocarboxylic Acid Transporters/genetics ; Mouth Neoplasms/drug therapy ; Muscle Proteins/genetics ; Muscle Proteins/pharmacology ; Sequence Analysis, RNA ; Squamous Cell Carcinoma of Head and Neck/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging.
Autorzy:
Sadeghzadeh M; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Wenzel B; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Gündel D; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Deuther-Conrad W; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Toussaint M; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Moldovan RP; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Fischer S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Ludwig FA; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Teodoro R; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
Jonnalagadda S; Department of Chemistry and Biochemistry, Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN 55812, USA.
Jonnalagadda SK; Department of Chemistry and Biochemistry, Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN 55812, USA.
Schüürmann G; UFZ Department of Ecological Chemistry, Helmholtz Centre for Environmental Research, Permoserstraße 15, 04318 Leipzig, Germany.; Institute of Organic Chemistry, Technical University Bergakademie Freiberg, Leipziger Straße 29, 09599 Freiberg, Germany.
Mereddy VR; Department of Chemistry and Biochemistry, Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN 55812, USA.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, 251 SMed, 1035 University Drive, Duluth, MN 55812, USA.
Brust P; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße 15, 04318 Leipzig, Germany.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 May 14; Vol. 25 (10). Date of Electronic Publication: 2020 May 14.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Brain/*diagnostic imaging
Monocarboxylic Acid Transporters/*metabolism
Positron-Emission Tomography/*methods
Pyridines/*chemical synthesis
Radiopharmaceuticals/*chemical synthesis
Symporters/*metabolism
Animals ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Brain/cytology ; Brain/metabolism ; Cell Line ; Coumaric Acids/pharmacology ; Drug Evaluation, Preclinical ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Female ; Fluorine Radioisotopes ; Ligands ; Mice ; Monocarboxylic Acid Transporters/antagonists & inhibitors ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/metabolism ; Pyridines/pharmacokinetics ; Radiopharmaceuticals/pharmacokinetics ; Rats ; Symporters/antagonists & inhibitors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
This was the year that was: brain barriers and brain fluid research in 2019.
Autorzy:
Keep RF; Department of Neurosurgery, University of Michigan, R5018 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200, USA. .
Jones HC; Gagle Brook House, Chesterton, Bicester, OX26 1UF, UK.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2020 Mar 05; Vol. 17 (1), pp. 20. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:
Editorial
MeSH Terms:
Brain Diseases*/metabolism
Brain Diseases*/physiopathology
Cerebrospinal Fluid*
Brain/*physiology
Animals ; Blood-Brain Barrier/physiology ; Brain/metabolism ; Glymphatic System/physiology ; Humans
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CNS fluid and solute movement: physiology, modelling and imaging.
Autorzy:
Jones HC; Gagle Brook House, Chesterton, Bicester, OX26 1UF, UK. .
Keep RF; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, 48105, USA.
Drewes LR; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, MN, 55812, USA.
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2020 Feb 04; Vol. 17 (1), pp. 12. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji:
Editorial; Introductory Journal Article
MeSH Terms:
Central Nervous System*
Cerebrospinal Fluid*
Models, Neurological*
Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment.
Autorzy:
Nelson GL; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Ronayne CT; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Solano LN; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Jonnalagadda SK; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Jonnalagadda S; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
Rumbley J; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.; Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN, 55812, USA.
Holy J; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.; Department of Biomedical Sciences, Medical School Duluth, University of Minnesota, Duluth, MN, 55812, USA.
Rose-Hellekant T; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.; Department of Biomedical Sciences, Medical School Duluth, University of Minnesota, Duluth, MN, 55812, USA.
Drewes LR; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.; Department of Biomedical Sciences, Medical School Duluth, University of Minnesota, Duluth, MN, 55812, USA.
Mereddy VR; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA. .; Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, 55812, USA. .; Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN, 55812, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Dec 04; Vol. 9 (1), pp. 18266. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Drug Discovery*
Antineoplastic Agents/*pharmacology
Cinnamates/*pharmacology
Colorectal Neoplasms/*drug therapy
Coumaric Acids/*pharmacology
Monocarboxylic Acid Transporters/*antagonists & inhibitors
Symporters/*antagonists & inhibitors
Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cinnamates/therapeutic use ; Coumaric Acids/therapeutic use ; Humans ; Mice ; Mitochondria/drug effects ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 27

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