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Wyszukujesz frazę ""Drug Delivery Systems"" wg kryterium: Temat


Tytuł :
Biorelevant dissolution testing and physiologically based absorption modeling to predict in vivo performance of supersaturating drug delivery systems.
Autorzy :
Thakore SD; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Sirvi A; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Joshi VC; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Panigrahi SS; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Manna A; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Singh R; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Sangamwar AT; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India.
Bansal AK; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Mohali, Punjab 160062, India. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Sep 25; Vol. 607, pp. 120958. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Pharmaceutical Preparations*
Administration, Oral ; Excipients ; Permeability ; Solubility
Czasopismo naukowe
Tytuł :
Gemcitabine lipid prodrug nanoparticles: Switching the lipid moiety and changing the fate in the bloodstream.
Autorzy :
Coppens E; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Desmaële D; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Naret T; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SCBM, Bat 547, 91191 Gif-sur-Yvette, France.
Garcia-Argote S; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SCBM, Bat 547, 91191 Gif-sur-Yvette, France.
Feuillastre S; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SCBM, Bat 547, 91191 Gif-sur-Yvette, France.
Pieters G; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SCBM, Bat 547, 91191 Gif-sur-Yvette, France.
Cailleau C; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Paul JL; AP-HP, Hôpital Européen Georges Pompidou, Service de Biochimie, 75015 Paris, France; Lip(Sys)(2), Athérosclérose: homéostasie et trafic du cholestérol des macrophages, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Prost B; SAMM, UMS IPSIT, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Solgadi A; SAMM, UMS IPSIT, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Michel JP; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Noiray M; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Couvreur P; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
Mura S; Institut Galien Paris-Saclay, UMR 8612, CNRS, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Nov 20; Vol. 609, pp. 121076. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article
MeSH Terms :
Deoxycytidine*/analogs & derivatives
Deoxycytidine*/pharmacokinetics
Drug Delivery Systems*
Nanoparticles*
Prodrugs*
Animals ; Humans ; Lipids ; Male ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Mitochondrial defects: An emerging theranostic avenue towards Alzheimer's associated dysregulations.
Autorzy :
Mani S; Centre for Emerging Diseases, Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida, UP 201307, India. Electronic address: .
Swargiary G; Centre for Emerging Diseases, Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida, UP 201307, India.
Singh M; Centre for Emerging Diseases, Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida, UP 201307, India.
Agarwal S; Macquarie University, NSW 2109, Australia.
Dey A; Department of Life Sciences, Presidency University, College Street, Kolkata 700073, India.
Ojha S; Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 17666, United Arab Emirates.
Jha NK; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Greater Noida, Uttar Pradesh 201310, India.
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Źródło :
Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 119985. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Alzheimer Disease/*drug therapy
Alzheimer Disease/*pathology
Mitochondria/*pathology
Amyloid beta-Protein Precursor/metabolism ; Energy Metabolism ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondrial Dynamics ; Mitophagy ; Neurons/metabolism ; Neurons/ultrastructure ; Precision Medicine/trends
Czasopismo naukowe
Tytuł :
Multienzyme nanoassemblies: from rational design to biomedical applications.
Autorzy :
Li D; State Key Lab of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. .; School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore. .; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Xiong Q; School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore. .
Liang L; State Key Lab of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. .; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Duan H; School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore. .
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Źródło :
Biomaterials science [Biomater Sci] 2021 Nov 09; Vol. 9 (22), pp. 7323-7342. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Czasopismo naukowe
Tytuł :
Advances in smart delivery of food bioactive compounds using stimuli-responsive carriers: Responsive mechanism, contemporary challenges, and prospects.
Autorzy :
Shishir MRI; College of Civil and Transportation Engineering, Shenzhen University, Shenzhen, China.; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; Institute for Innovative Development of Food Industry, Shenzhen University, Shenzhen, China.
Gowd V; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; Institute for Innovative Development of Food Industry, Shenzhen University, Shenzhen, China.
Suo H; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; Institute for Innovative Development of Food Industry, Shenzhen University, Shenzhen, China.
Wang M; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, P. R. China.
Wang Q; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences/Key Laboratory of Agro-Products Processing, Ministry of Agriculture, Beijing, China.
Chen F; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; Institute for Innovative Development of Food Industry, Shenzhen University, Shenzhen, China.
Cheng KW; Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, China.; Institute for Innovative Development of Food Industry, Shenzhen University, Shenzhen, China.
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Źródło :
Comprehensive reviews in food science and food safety [Compr Rev Food Sci Food Saf] 2021 Nov; Vol. 20 (6), pp. 5449-5488. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Carriers*
Drug Delivery Systems*
Drug Compounding ; Hydrogen-Ion Concentration ; Temperature
Czasopismo naukowe
Tytuł :
Intrathecal implantation surgical considerations in rodents; a review.
Autorzy :
Arman A; ARC Centre of Excellence for Nanoscale Biophotonics, The University of Adelaide, SA 5000, Australia; Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia.
Hutchinson MR; ARC Centre of Excellence for Nanoscale Biophotonics, The University of Adelaide, SA 5000, Australia; Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia. Electronic address: .
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2021 Nov 01; Vol. 363, pp. 109327. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Delivery Systems*
Rodentia*
Animals ; Humans ; Injections, Spinal ; Preoperative Care
Czasopismo naukowe
Tytuł :
Development of lipoprotein-drug conjugates for targeted drug delivery.
Autorzy :
Bhatia MS; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, India.
Choudhari SP; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, India.
Dhavale RP; Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur, India.
Gaikwad VL; Department of Pharmaceutics, BVDU Poona College of Pharmacy, Pune, India.
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Źródło :
Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2021 Nov; Vol. 39 (18), pp. 6955-6973. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Drug Delivery Systems*
Pharmaceutical Preparations*
Drug Carriers ; Drug Liberation ; HaCaT Cells ; Humans ; Lipoproteins
Czasopismo naukowe
Tytuł :
Molecular bottlebrush with pH-responsive cleavable bonds as a unimolecular vehicle for anticancer drug delivery.
Autorzy :
Raj W; Lodz University of Technology, Institute of Polymer and Dye Technology, Stefanowskiego 16, 90-537 Lodz, Poland.
Jerczynski K; Lodz University of Technology, Institute of Polymer and Dye Technology, Stefanowskiego 16, 90-537 Lodz, Poland.
Rahimi M; Lodz University of Technology, Institute of Polymer and Dye Technology, Stefanowskiego 16, 90-537 Lodz, Poland.
Przekora A; Medical University of Lublin, Independent Unit of Tissue Engineering and Regenerative Medicine, Chair of Biomedical Sciences, Chodzki 1 Street, 20-093 Lublin, Poland.
Matyjaszewski K; Carnegie Mellon University, Department of Chemistry, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.
Pietrasik J; Lodz University of Technology, Institute of Polymer and Dye Technology, Stefanowskiego 16, 90-537 Lodz, Poland. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2021 Nov; Vol. 130, pp. 112439. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Drug Delivery Systems*
Doxorubicin/pharmacology ; Drug Carriers ; Drug Liberation ; Humans ; Hydrogen-Ion Concentration ; Micelles ; Polymers
Czasopismo naukowe
Tytuł :
Panorama of dissolving microneedles for transdermal drug delivery.
Autorzy :
Dalvi M; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.
Kharat P; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.
Thakor P; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.
Bhavana V; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.
Singh SB; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India.
Mehra NK; Pharmaceutical Nanotechnology Research Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 01; Vol. 284, pp. 119877. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Microinjections*
Needles*
Administration, Cutaneous ; Animals ; Computer Simulation ; Humans ; Microtechnology
Czasopismo naukowe
Tytuł :
Bottom-up cubosome synthesis without organic solvents.
Autorzy :
Bryant SJ; School of Science, RMIT University, Melbourne, Victoria 3001, Australia; Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: .
Bathke EK; Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom.
Edler KJ; Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: .
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Źródło :
Journal of colloid and interface science [J Colloid Interface Sci] 2021 Nov; Vol. 601, pp. 98-105. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Poloxamer*
Excipients ; Liposomes ; Solvents
Czasopismo naukowe
Tytuł :
Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19.
Autorzy :
Brain D; Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Plant-Hately A; Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Heaton B; Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Arshad U; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
David C; Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Hedrich C; Department of Women's & Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK; Department of Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
Owen A; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Liptrott NJ; Immunocompatibility Group, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK; Centre of Excellence for Long-acting Therapeutics (CELT), Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. Electronic address: .
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Źródło :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2021 Nov; Vol. 178, pp. 113848. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antiviral Agents/*administration & dosage
COVID-19/*drug therapy
Drug Delivery Systems/*methods
Immunologic Factors/*administration & dosage
Inflammasomes/*antagonists & inhibitors
Adjuvants, Immunologic/administration & dosage ; Animals ; Antiviral Agents/immunology ; COVID-19/immunology ; Communicable Diseases/drug therapy ; Communicable Diseases/immunology ; Complement Activation/drug effects ; Complement Activation/immunology ; Drug Delivery Systems/trends ; Humans ; Immunologic Factors/immunology ; Inflammasomes/immunology
Czasopismo naukowe
Tytuł :
In vitro evaluation of adhesion and mechanical properties of oral thin films.
Autorzy :
Alaei S; College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL 33328, United States.
Omidi Y; College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL 33328, United States.
Omidian H; College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL 33328, United States. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Nov 01; Vol. 166, pp. 105965. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Pharmaceutical Preparations*/metabolism
Adhesiveness ; Adhesives/metabolism ; Biological Availability ; Humans ; Mouth Mucosa/metabolism
Czasopismo naukowe
Tytuł :
Breaking the barriers for the delivery of amikacin: Challenges, strategies, and opportunities.
Autorzy :
Maxwell A; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
Ghate V; Mechatronics Lab, Department of Electronic System Engineering, Indian Institute of Science, Bengaluru 560012, Karnataka, India.
Aranjani J; Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India.
Lewis S; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 01; Vol. 284, pp. 119883. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Delivery Systems*
Amikacin/*administration & dosage
Amikacin/chemistry ; Amikacin/pharmacokinetics ; Animals ; Clinical Trials as Topic ; Drug Carriers/chemistry ; Drug Liberation ; Humans ; Nanoparticles/chemistry ; Nanoparticles/ultrastructure
Czasopismo naukowe
Tytuł :
A novel versatile flow-donor chamber as biorelevant ex-vivo test assessing oral mucoadhesive formulations.
Autorzy :
Gidvall S; Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden; Biofilms - Research Center for Biointerfaces (BRCB), Malmö University, SE-205 06 Malmö, Sweden.
Björklund S; Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden; Biofilms - Research Center for Biointerfaces (BRCB), Malmö University, SE-205 06 Malmö, Sweden.
Feiler A; Nanologica AB, SE-151 36 Södertälje, Sweden; Chemistry Department, KTH, Royal Institute of Technology, 100 44 Stockholm, Sweden.
Dahlström B; CTC Clinical Trial Consultants AB, 75237 Uppsala.
Rönn R; Orexo AB, 754 50 Uppsala, Sweden.
Engblom J; Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden; Biofilms - Research Center for Biointerfaces (BRCB), Malmö University, SE-205 06 Malmö, Sweden.
Valetti S; Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden; Biofilms - Research Center for Biointerfaces (BRCB), Malmö University, SE-205 06 Malmö, Sweden. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Nov 01; Vol. 166, pp. 105983. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Mouth Mucosa*
Excipients ; Polymers ; Tablets
Czasopismo naukowe
Tytuł :
A design approach for layer-by-layer surface-mediated siRNA delivery.
Autorzy :
Chou JJ; Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States. Electronic address: .
Berger AG; Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, United States. Electronic address: .
Jalili-Firoozinezhad S; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States. Electronic address: .
Hammond PT; Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, United States; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States. Electronic address: .
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Źródło :
Acta biomaterialia [Acta Biomater] 2021 Nov; Vol. 135, pp. 331-341. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Drug Delivery Systems*
Wound Healing*
Polyelectrolytes ; RNA, Small Interfering ; Transfection
Czasopismo naukowe
Tytuł :
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays.
Autorzy :
Gupta Y; Infectious Diseases, Mayo Clinic, Jacksonville, FL, USA.
Maciorowski D; Loyola University Chicago, Chicago, IL, USA.
Zak SE; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA.
Jones KA; Department of Chemistry, The University of Chicago, 5801 South Ellis Avenue, Chicago, IL, USA.
Kathayat RS; Department of Chemistry, The University of Chicago, 5801 South Ellis Avenue, Chicago, IL, USA.
Azizi SA; Department of Chemistry, The University of Chicago, 5801 South Ellis Avenue, Chicago, IL, USA.
Mathur R; Loyola University Chicago, Chicago, IL, USA.
Pearce CM; Loyola University Chicago, Chicago, IL, USA.
Ilc DJ; Loyola University Chicago, Chicago, IL, USA.
Husein H; Loyola University Chicago, Chicago, IL, USA.
Herbert AS; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA.
Bharti A; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, CA, 92093, USA.
Rathi B; Laboratory for Translational Chemistry and Drug Discovery, Hansraj College, University of Delhi, India.
Durvasula R; Infectious Diseases, Mayo Clinic, Jacksonville, FL, USA.
Becker DP; Loyola University Chicago, Chicago, IL, USA.
Dickinson BC; Department of Chemistry, The University of Chicago, 5801 South Ellis Avenue, Chicago, IL, USA.
Dye JM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA. Electronic address: .
Kempaiah P; Infectious Diseases, Mayo Clinic, Jacksonville, FL, USA. Electronic address: .
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Źródło :
Methods (San Diego, Calif.) [Methods] 2021 Nov; Vol. 195, pp. 57-71. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*administration & dosage
Coronavirus 3C Proteases/*antagonists & inhibitors
Drug Delivery Systems/*standards
Indoles/*administration & dosage
Maleimides/*administration & dosage
SARS-CoV-2/*drug effects
SARS-CoV-2/*enzymology
Antiviral Agents/metabolism ; Coronavirus 3C Proteases/chemistry ; Coronavirus 3C Proteases/metabolism ; Dose-Response Relationship, Drug ; Drug Delivery Systems/methods ; Drug Evaluation, Preclinical/methods ; Drug Repositioning/methods ; Drug Repositioning/standards ; High-Throughput Screening Assays/methods ; High-Throughput Screening Assays/standards ; Humans ; Indoles/chemistry ; Indoles/metabolism ; Maleimides/chemistry ; Maleimides/metabolism ; Molecular Docking Simulation/methods ; Molecular Docking Simulation/standards ; Protein Structure, Secondary ; Reproducibility of Results ; SARS-CoV-2/chemistry
Czasopismo naukowe
Tytuł :
Nucleic acid delivery for therapeutic applications.
Autorzy :
Gupta A; David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA.
Andresen JL; David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Manan RS; David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Langer R; David H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: .
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Źródło :
Advanced drug delivery reviews [Adv Drug Deliv Rev] 2021 Nov; Vol. 178, pp. 113834. Date of Electronic Publication: 2021 Sep 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Drug Delivery Systems/*trends
Gene Transfer Techniques/*trends
Nucleic Acids/*administration & dosage
Nucleic Acids/*genetics
Oligonucleotides, Antisense/*administration & dosage
Oligonucleotides, Antisense/*genetics
Animals ; COVID-19/genetics ; COVID-19/metabolism ; COVID-19/therapy ; Clinical Trials as Topic/methods ; Drug Approval ; Drug Delivery Systems/methods ; Hepatitis/genetics ; Hepatitis/metabolism ; Hepatitis/therapy ; Humans ; MicroRNAs/administration & dosage ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/therapy ; Nucleic Acids/metabolism ; Oligonucleotides, Antisense/metabolism ; RNA, Messenger/administration & dosage ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Tytuł :
Evaluating the single-molecule interactions between targeted peptides and the receptors on living cell membrane.
Autorzy :
Li S; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.; School of Chemical Engineering, Changchun University of Technology, Changchun 130012, China.
Pang X; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
Zhao J; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
Zhang Q; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
Shan Y; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
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Źródło :
Nanoscale [Nanoscale] 2021 Oct 28; Vol. 13 (41), pp. 17318-17324. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Peptides*
Cell Line, Tumor ; Cell Membrane ; Ligands ; Microscopy, Atomic Force
Czasopismo naukowe
Tytuł :
An Overview of Micronanoswarms for Biomedical Applications.
Autorzy :
Chen H; School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.; Shenzhen Institute of Artificial Intelligence and Robotics for Society (AIRS), Shenzhen 518129, China.
Zhang H; School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.
Xu T; Shenzhen Institute of Artificial Intelligence and Robotics for Society (AIRS), Shenzhen 518129, China.; Guangdong Provincial Key Laboratory of Robotics and Intelligent System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518126, China.
Yu J; School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.; Shenzhen Institute of Artificial Intelligence and Robotics for Society (AIRS), Shenzhen 518129, China.
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Źródło :
ACS nano [ACS Nano] 2021 Oct 26; Vol. 15 (10), pp. 15625-15644. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Diagnostic Imaging*
Drug Delivery Systems*
Motion
Czasopismo naukowe
Tytuł :
Design of long acting invasomal nanovesicles for improved transdermal permeation and bioavailability of asenapine maleate for the chronic treatment of schizophrenia.
Autorzy :
El-Tokhy FS; Department of Pharmaceutics, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, Egypt.
Abdel-Mottaleb MMA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Electronic address: .
El-Ghany EA; Department of Pharmaceutics, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, Egypt.
Geneidi AS; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Oct 25; Vol. 608, pp. 121080. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Schizophrenia*
Dibenzocycloheptenes/*administration & dosage
Administration, Cutaneous ; Animals ; Biological Availability ; Female ; Particle Size ; Rats ; Rats, Wistar ; Skin/metabolism
Czasopismo naukowe

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