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Wyświetlanie 21-40 z 47847
Tytuł:
Exploration of the Binding Mechanism of Cyclic Dinucleotide Analogs to Stimulating Factor Proteins and the Implications for Subsequent Analog Drug Design.
Autorzy:
Yuan, Shu-Wei (AUTHOR)
Shi, Hong-Ling (AUTHOR)
Fu, Mu-Ran (AUTHOR)
Zhang, Xi-Chuan (AUTHOR)
Xi, Xiao-Qi (AUTHOR)
Wang, Yao (AUTHOR)
Shen, Tai-Song (AUTHOR)
Ma, Jin-Liang (AUTHOR)
Tang, Cun-Duo (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Mar2024, Vol. 14 Issue 3, p350. 22p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dockey: a modern integrated tool for large-scale molecular docking and virtual screening.
Autorzy:
Du L; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.; Institute for Advanced Study, Chengdu University, Chengdu 610106, China.
Geng C; College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Zeng Q; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.
Huang T; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.
Tang J; College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
Chu Y; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.
Zhao K; Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, School of Pharmacy, Chengdu University, Chengdu 610106, China.
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Źródło:
Briefings in bioinformatics [Brief Bioinform] 2023 Mar 19; Vol. 24 (2).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proteins*/metabolism
Drug Design*
Molecular Docking Simulation ; Drug Discovery ; Ligands ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny.
Autorzy:
Alshaye NA; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Elgohary MK; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt.
Elkotamy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt.
Abdel-Aziz HA; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 15; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclooxygenase 2 Inhibitors*
Anti-Inflammatory Agents*/therapeutic use
Humans ; Cyclooxygenase 2/metabolism ; Acetic Acid ; Molecular Docking Simulation ; Inflammation/drug therapy ; Edema/drug therapy ; Structure-Activity Relationship ; Drug Design ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3- d ][1,2,4]triazolo[1,5- a ]pyrimidine Derivatives.
Autorzy:
Elsenbawy ESM; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
Alshehri ZS; Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Dawadmi 19257, Saudi Arabia.
Babteen NA; Department of Biochemistry, College of Sciences, University of Jeddah, Jeddah 21577, Saudi Arabia.
Abdel-Rahman AA; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt.
El-Manawaty MA; Department of Pharmacognosy, Pharmaceutical Science Division, National Research Centre, Cairo 12622, Egypt.
Nossier ES; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.
Arafa RK; Drug Design and Discovery Laboratory, Biomedical Sciences Program, University of Science and Technology, Zewail City of Science and Technology, Ahmed Zewail Road, October Gardens, Cairo 12578, Egypt.
Hassan NA; Synthetic Unit, Department of Photochemistry, Chemical Industries Research Institute, National Research Centre, Cairo 12622, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 29; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Humans ; Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Pyrimidines/pharmacology ; Triazoles/pharmacology ; Drug Screening Assays, Antitumor ; Cell Proliferation ; Cell Line, Tumor ; Drug Design
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Special Issue "Computer-Aided Drug Discovery and Treatment".
Autorzy:
Ilan Y; Department of Medicine, Hadassah Medical Center, Faculty of Medicine, Hebrew University, Jerusalem 91120, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 26; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Editorial
MeSH Terms:
Computer-Aided Design*
Anti-HIV Agents*
Drug Discovery ; Computers ; Hydrolases ; Drug Design
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and Insecticidal Activity of Novel Anthranilic Diamide Insecticides Containing Indane and Its Analogs.
Autorzy:
Yang Z; Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, China.
Hu R; Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, China.
Chen J; Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, China.
Du X; Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 19; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Insecticides*/chemistry
Moths*
ortho-Aminobenzoates*
Animals ; Diamide/pharmacology ; Drug Design ; Structure-Activity Relationship ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present).
Autorzy:
Abdel-Mohsen HT; Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Anwar MM; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Ahmed NS; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Abd El-Karim SS; Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre, El-Bohouth Street, Dokki, Cairo P.O. Box 12622, Egypt.
Abdelwahed SH; Department of Chemistry, Prairie View A & M University, Prairie View, TX 77446, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 16; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Neoplasms*/drug therapy
Neoplasms*/metabolism
Humans ; Quinazolines/pharmacology ; Quinazolines/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Drug Design ; Protein Kinases/metabolism ; Structure-Activity Relationship ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Autorzy:
Wu KJY; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Tresco BIC; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Ramkissoon A; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Aleksandrova EV; Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Syroegin EA; Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
See DNY; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Liow P; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Dittemore GA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Yu M; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Testolin G; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Mitcheltree MJ; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Liu RY; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Svetlov MS; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Polikanov YS; Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Myers AG; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 16; Vol. 383 (6684), pp. 721-726. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents*/chemical synthesis
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/pharmacology
Drug Resistance, Multiple, Bacterial*
Bridged-Ring Compounds*/chemical synthesis
Bridged-Ring Compounds*/chemistry
Bridged-Ring Compounds*/pharmacology
Oxepins*/chemical synthesis
Oxepins*/chemistry
Oxepins*/pharmacology
Lincosamides*/chemical synthesis
Lincosamides*/chemistry
Lincosamides*/pharmacology
Erythromycin/chemistry ; Erythromycin/pharmacology ; Microbial Sensitivity Tests ; Staphylococcus aureus/drug effects ; Escherichia coli/drug effects ; Pseudomonas aeruginosa/drug effects ; Animals ; Mice ; Drug Design ; Ribosomes/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design.
Autorzy:
Turnaturi R; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Piana S; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Spoto S; Department of Drug and Health Sciences, Pharmacology and Toxicology Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Costanzo G; Department of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 97, 95123 Catania, Italy.
Reina L; Postgraduate School of Clinical Pharmacology and Toxicology, University of Catania, Via Santa Sofia 97, 95123 Catania, Italy.
Pasquinucci L; Department of Drug and Health Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Parenti C; Department of Drug and Health Sciences, Pharmacology and Toxicology Section, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 09; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Plants, Medicinal*
Biological Products*/therapeutic use
Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use ; Chemistry, Pharmaceutical ; Quality of Life ; Pain/drug therapy ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Drug Design
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments.
Autorzy:
Mehany MM; Laboratory Department, Chemistry Unit, Police Hospital, Agouza, Cairo, Egypt.
Hammam OA; Pathology Department, Theodor Bilharz Research Institute, Giza, Egypt.
Selim AA; Labeled Compounds Department, Hot Laboratories Centre, Egyptian Atomic Energy Authority (EAEA), Cairo, 13759, Egypt. adli_a_.
Sayed GH; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Anwer KE; Heterocyclic Synthesis Lab., Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2738. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Iodine Radioisotopes*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Animals ; Mice ; MCF-7 Cells ; Caco-2 Cells ; Cell Proliferation ; Pyridines/pharmacology ; Pyridines/chemistry ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Drug Design ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Potential Lead for Insect Growth Regulator: Design, Synthesis, and Biological Activity Evaluation of Novel Hexacyclic Pyrazolamide Derivatives.
Autorzy:
Guo B; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Jiang B; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Wang C; Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.
Jin X; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Wang L; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Yang Z; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Luo S; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Yang Q; State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Zhang L; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Yang X; Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Apr 26; Vol. 28 (9). Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Insecticides*/chemical synthesis
Insecticides*/chemistry
Insecticides*/pharmacology
Juvenile Hormones*/chemical synthesis
Juvenile Hormones*/chemistry
Juvenile Hormones*/pharmacology
Drug Design*
Insecta*/drug effects
Insecta*/growth & development
Animals ; Chitinases/antagonists & inhibitors ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Autorzy:
Mao C; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Xiao P; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Tao XN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Qin J; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
He QT; Department of Orthopedics, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhang C; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Guo SC; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Du YQ; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.
Chen LN; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Shen DD; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Yang ZS; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhang HQ; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Huang SM; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.
He YH; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Cheng J; Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
Zhong YN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Shang P; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
Chen J; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhang DL; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Wang QL; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Liu MX; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Li GY; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Guo Y; Department of Orthopedics, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Xu HE; CAS Key Laboratory of Receptor Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Wang C; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Zhang C; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Feng S; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.; Department of Orthopedics, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Yu X; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
Zhang Y; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou 311121, China.; MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China.; Research and Development Center for E-Learning, Ministry of Education, Beijing 100816, China.
Sun JP; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.; Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Apr 07; Vol. 380 (6640), pp. eadd6220. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, G-Protein-Coupled*/agonists
Receptors, G-Protein-Coupled*/chemistry
Receptors, G-Protein-Coupled*/genetics
Fatty Acids, Omega-3*/chemistry
Fatty Acids, Omega-3*/metabolism
Drug Design*
Cryoelectron Microscopy ; Ligands ; Humans ; Biphenyl Compounds/chemistry ; Biphenyl Compounds/pharmacology ; Phenylpropionates/chemistry ; Phenylpropionates/pharmacology ; Protein Conformation ; Eicosapentaenoic Acid/chemistry ; Eicosapentaenoic Acid/metabolism ; Mutation, Missense ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 21-40 z 47847

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