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Wyszukujesz frazę ""Drug Interactions"" wg kryterium: Temat


Starter badań:

Tytuł :
Drug interactions with Bruton's tyrosine kinase inhibitors: clinical implications and management.
Autorzy :
Fancher KM; Duquesne University School of Pharmacy, 322 Bayer Building, 600 Forbes Avenue, Pittsburgh, PA, 15282, USA. .; University of Pittsburgh Medical Center Passavant, Pittsburgh, PA, USA. .
Pappacena JJ; Allegheny Health Network, Pittsburgh, PA, USA.
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Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2020 Oct; Vol. 86 (4), pp. 507-515. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Food-Drug Interactions*
Agammaglobulinaemia Tyrosine Kinase/*antagonists & inhibitors
Hematologic Neoplasms/*drug therapy
Lymphoproliferative Disorders/*drug therapy
Protein Kinase Inhibitors/*pharmacokinetics
Adenine/administration & dosage ; Adenine/analogs & derivatives ; Adenine/pharmacokinetics ; Benzamides/administration & dosage ; Benzamides/pharmacokinetics ; Citrus paradisi ; Citrus sinensis ; Comorbidity ; Cytochrome P-450 CYP2D6/metabolism ; Cytochrome P-450 CYP2D6 Inducers/administration & dosage ; Cytochrome P-450 CYP2D6 Inducers/pharmacokinetics ; Cytochrome P-450 CYP2D6 Inhibitors/administration & dosage ; Cytochrome P-450 CYP2D6 Inhibitors/pharmacokinetics ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 CYP3A Inducers/administration & dosage ; Cytochrome P-450 CYP3A Inducers/pharmacokinetics ; Cytochrome P-450 CYP3A Inhibitors/administration & dosage ; Cytochrome P-450 CYP3A Inhibitors/pharmacokinetics ; Drug Interactions ; Fruit and Vegetable Juices ; Hematologic Neoplasms/epidemiology ; Humans ; Lymphoproliferative Disorders/epidemiology ; Piperidines/administration & dosage ; Piperidines/pharmacokinetics ; Polypharmacy ; Protein Kinase Inhibitors/administration & dosage ; Pyrazines/administration & dosage ; Pyrazines/pharmacokinetics ; Pyrazoles/administration & dosage ; Pyrazoles/pharmacokinetics ; Pyrimidines/administration & dosage ; Pyrimidines/pharmacokinetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Application of Physiologically-Based Pharmacokinetic Modeling to Predict Gastric pH-Dependent Drug-Drug Interactions for Weak Base Drugs.
Autorzy :
Dong Z; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Li J; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Wu F; Office of New Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Zhao P; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Lee SC; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Zhang L; Office of Policy for Pharmaceutical Quality, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Seo P; Office of New Drug Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Zhang L; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
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Źródło :
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2020 Aug; Vol. 9 (8), pp. 456-465. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Drug Interactions*
Models, Biological*
Pharmaceutical Preparations/*metabolism
Computer Simulation ; Food-Drug Interactions ; Humans ; Hydrogen-Ion Concentration ; Pharmaceutical Preparations/chemistry
Czasopismo naukowe
Tytuł :
Medication Errors During Treatment with New Oral Anticancer Agents: Consequences for Clinical Practice Based on the AMBORA Study.
Autorzy :
Schlichtig K; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN, Erlangen University Hospital, Erlangen, Germany.
Dürr P; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN, Erlangen University Hospital, Erlangen, Germany.; Pharmacy Department, Erlangen University Hospital, Erlangen, Germany.
Dörje F; Comprehensive Cancer Center Erlangen-EMN, Erlangen University Hospital, Erlangen, Germany.; Pharmacy Department, Erlangen University Hospital, Erlangen, Germany.
Fromm MF; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN, Erlangen University Hospital, Erlangen, Germany.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Oct; Vol. 110 (4), pp. 1075-1086. Date of Electronic Publication: 2021 Jul 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Interactions*
Food-Drug Interactions*
Polypharmacy*
Antineoplastic Agents/*therapeutic use
Medication Errors/*statistics & numerical data
Neoplasms/*drug therapy
Administration, Oral ; Adult ; Aged ; Aged, 80 and over ; Analgesics/therapeutic use ; Anti-Ulcer Agents/therapeutic use ; Antihypertensive Agents/therapeutic use ; Antineoplastic Agents, Hormonal/therapeutic use ; Comorbidity ; Coronary Disease/drug therapy ; Coronary Disease/epidemiology ; Decision Support Systems, Clinical ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/epidemiology ; Dyslipidemias/drug therapy ; Dyslipidemias/epidemiology ; Female ; Fibrinolytic Agents/therapeutic use ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Hypolipidemic Agents/therapeutic use ; Hypothyroidism/drug therapy ; Hypothyroidism/epidemiology ; Male ; Middle Aged ; Protein Kinase Inhibitors/therapeutic use ; Thyroid Hormones/therapeutic use ; Vitamins/therapeutic use
Czasopismo naukowe
Tytuł :
[Interactions between herbals medicines and drugs in chronic patients with complexity in primary care.]
Autorzy :
Lázaro Romero E; Centro de Atención Especializada Mataró-Maresme. Institut Català de la Salut. Mataró (Barcelona). España.; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.
Miranda Sánchez J; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Pinetons. Institut Català de la Salut. Ripollet (Barcelona). España.
Zurilla Leonarte E; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Gatassa. Institut Català de la Salut. Mataró (Barcelona). España.
Vedia Urgell C; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Unidad de Farmacia. Servicio de Atención Primaria Barcelonés Nord i Maresme. Institut Català de la Salut. Badalona (Barcelona). España.; Grupo consolidado Unitat d'Estudis del Medicament. Institut Universitari d'Investigació en Atenció Primària (IDIAP Jordi Gol). Barcelona. España.; Departamento Farmacologia. Facultad de Medicina. UD St Pau. Universidad Autònoma de Barcelona. Cerdanyola del Vallès (Barcelona). España.
Massot Mesquida M; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Unidad de Farmacia. Servicio de Atención Primaria Vallés Occidental. Institut Català de la Salut. Sabadell (Barcelona). España.; Grup de Recerca Multidisciplinar en Salut i Societat (GREMSAS). Mataró (Barcelona). España.
Serrano Serrano E; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud El Masnou. Institut Català de la Salut. Masnou (Barcelona). España.
Solanellas Colomer L; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Gatassa. Institut Català de la Salut. Mataró (Barcelona). España.
Martínez Luque RM; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Pinetons. Institut Català de la Salut. Ripollet (Barcelona). España.
Castillejo Medina JM; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Pinetons. Institut Català de la Salut. Ripollet (Barcelona). España.
Merino Domínguez E; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Área Básica de Salud Pinetons. Institut Català de la Salut. Ripollet (Barcelona). España.
Seda Gombau G; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Grup de Recerca Multidisciplinar en Salut i Societat (GREMSAS). Mataró (Barcelona). España.
Torán Monserrat P; Unitat de Suport a la Recerca Metropolitana Nord. Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol). Mataró (Barcelona). España.; Grup de Recerca Multidisciplinar en Salut i Societat (GREMSAS). Mataró (Barcelona). España.; Departament de Medicina. Facultat de Medicina. Universitat de Girona. Girona. España.
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Transliterated Title :
Interacciones entre plantas medicinales y medicamentos en pacientes crónicos complejos en atención primaria.
Źródło :
Revista espanola de salud publica [Rev Esp Salud Publica] 2021 Aug 30; Vol. 95. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Chronic Disease*/drug therapy
Herb-Drug Interactions*
Primary Health Care*
Aged ; Female ; Humans ; Male ; Spain
Czasopismo naukowe
Tytuł :
The impact of catha edulis (vahl) forssk. ex endl . (celestraceae) (khat) on pharmacokinetics of clinically used drugs.
Autorzy :
Aklillu E; Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital-Huddinge, Stockholm, Sweden.
Engidawork E; Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Sep; Vol. 17 (9), pp. 1125-1138. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Herb-Drug Interactions*
Catha/*chemistry
Plant Extracts/*pharmacology
Central Nervous System Stimulants/isolation & purification ; Central Nervous System Stimulants/pharmacology ; Genotype ; Humans ; Pharmacogenetics ; Pharmacokinetics
Czasopismo naukowe
Tytuł :
Herb-drug interactions in diabetes mellitus: A review based on pre-clinical and clinical data.
Autorzy :
Thikekar AK; Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.
Thomas AB; Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.
Chitlange SS; Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Sep; Vol. 35 (9), pp. 4763-4781. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Mellitus*/drug therapy
Herb-Drug Interactions*
Plants, Medicinal*/adverse effects
Biological Transport ; Cytochrome P-450 Enzyme Inhibitors ; Cytochrome P-450 Enzyme System/metabolism ; Humans
Czasopismo naukowe
Tytuł :
The global profiling of alkaloids in Aconitum stapfianum and analysis of detoxification material basis against Fuzi.
Autorzy :
Liu S; School of Resources Environmental & Chemical Engineering, Nanchang University, Nanchang 330031, China.
Lai C; State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijng 100700, China.
Long Y; School of Resources Environmental & Chemical Engineering, Nanchang University, Nanchang 330031, China.
Yang W; School of Resources Environmental & Chemical Engineering, Nanchang University, Nanchang 330031, China. Electronic address: .
Ren Q; Jiangxi Institute for Drug Control, NMPA Key Laboratory of Quality Evaluation of Traditional Chinese Patent Medicine, Jiangxi Province Engineering Research Center of Drug and Medical Device Quality, Nanchang 330029, China.
Huang L; State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijng 100700, China. Electronic address: .
Chen J; School of Resources Environmental & Chemical Engineering, Nanchang University, Nanchang 330031, China; Center for Post-doctoral research, China Academy of Chinese Medical Sciences, Beijng 100700, China. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2021 Aug 30; Vol. 1652, pp. 462362. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article
MeSH Terms :
Aconitum*/chemistry
Alkaloids*/analysis
Alkaloids*/chemistry
Diterpenes*/chemistry
Drug Interactions*
Drugs, Chinese Herbal*/chemistry
Chromatography, High Pressure Liquid ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Roots/chemistry
Czasopismo naukowe
Tytuł :
The Interaction of Heptakis (2,6-di-O-Methyl)-β-cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity.
Autorzy :
Belica-Pacha S; Unit of Biophysical Chemistry, Department of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 165, 90-236 Lodz, Poland.
Małecka M; Unit of Biophysical Chemistry, Department of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 165, 90-236 Lodz, Poland.
Daśko M; Department of Inorganic Chemistry, Faculty of Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Miłowska K; Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Bryszewska M; Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Budryn G; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 4-10, 90-924 Lodz, Poland.
Oracz J; Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 4-10, 90-924 Lodz, Poland.
Pałecz B; Unit of Biophysical Chemistry, Department of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 165, 90-236 Lodz, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 30; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Interactions*
Cell Proliferation/*drug effects
Drug-Related Side Effects and Adverse Reactions/*pathology
Mianserin/*toxicity
beta-Cyclodextrins/*toxicity
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Drug-Related Side Effects and Adverse Reactions/etiology ; Histamine H1 Antagonists/toxicity ; Mianserin/metabolism ; Molecular Docking Simulation ; beta-Cyclodextrins/metabolism
Czasopismo naukowe
Tytuł :
The Clinical Significance of Drug-Food Interactions of Direct Oral Anticoagulants.
Autorzy :
Grześk G; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Rogowicz D; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Wołowiec Ł; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Ratajczak A; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Gilewski W; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Chudzińska M; Department of Nutrition and Dietetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Dębowa 3 Street, 85-626 Bydgoszcz, Poland.
Sinkiewicz A; Department of Otolaryngology, Audiology and Phoniatrics, University Hospital No. 2, Collegium Medicum, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
Banach J; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 08; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anticoagulants*/pharmacokinetics
Anticoagulants*/therapeutic use
Dietary Supplements*
Food-Drug Interactions*
Vitamin K*/antagonists & inhibitors
Vitamin K*/blood
Administration, Oral ; Humans
Czasopismo naukowe
Tytuł :
Do Inhibitory Metabolites Impact DDI Risk Assessment? Analysis of in vitro and in vivo Data from NDA Reviews Between 2013 and 2018.
Autorzy :
Steinbronn C; Department of Pharmaceutics, University of Washington, Seattle, Washington, USA.
Yang X; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Yu J; Department of Pharmaceutics, University of Washington, Seattle, Washington, USA.; UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.
Dimova H; Center for Tobacco Products, US Food and Drug Administration, Silver Spring, Maryland, USA.
Huang SM; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
Ragueneau-Majlessi I; Department of Pharmaceutics, University of Washington, Seattle, Washington, USA.; UW Drug Interaction Solutions, University of Washington, Seattle, Washington, USA.
Isoherranen N; Department of Pharmaceutics, University of Washington, Seattle, Washington, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Aug; Vol. 110 (2), pp. 452-463. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Interactions*
Pharmaceutical Preparations/*metabolism
Area Under Curve ; Biotransformation ; Cytochrome P-450 Enzyme Inhibitors/pharmacology ; Databases, Factual ; Humans ; Liver/metabolism ; Pharmacokinetics ; Risk Assessment
Czasopismo naukowe
Tytuł :
Ginkgo biloba leaf extract suppresses intestinal human breast cancer resistance protein expression in mice: Correlation with gut microbiota.
Autorzy :
Kim JK; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Choi MS; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do 15588, Republic of Korea.
Kim JY; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Yu JS; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do 15588, Republic of Korea.
Seo JI; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do 15588, Republic of Korea.
Yoo HH; Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do 15588, Republic of Korea. Electronic address: .
Kim DH; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111712. Date of Electronic Publication: 2021 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Herb-Drug Interactions*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism
Gastrointestinal Microbiome/*drug effects
Neoplasm Proteins/*metabolism
Plant Extracts/*pharmacology
Sulfasalazine/*pharmacokinetics
ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; Animals ; Caco-2 Cells ; Feces/chemistry ; Feces/microbiology ; Humans ; Male ; Metabolome ; Mice, Inbred C57BL ; Neoplasm Proteins/genetics ; Sulfasalazine/blood
Czasopismo naukowe
Tytuł :
Bioavailability and pharmacokinetic profile of balovaptan, a selective, brain-penetrant vasopressin 1a receptor antagonist, in healthy volunteers.
Autorzy :
Derks M; Roche Pharma Research & Early Development, Roche Innovation Center Welwyn, Roche Products Ltd, Welwyn Garden City, UK.
Lennon-Chrimes S; Roche Pharma Research & Early Development, Roche Innovation Center Welwyn, Roche Products Ltd, Welwyn Garden City, UK.
Guenther A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
Squassante L; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
Wandel C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
Szczesny P; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
Paehler A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
Kletzl H; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche AG, Basel, Switzerland.
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Źródło :
Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2021 Aug; Vol. 30 (8), pp. 893-901. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Food-Drug Interactions*
Antidiuretic Hormone Receptor Antagonists/*administration & dosage
Benzodiazepines/*administration & dosage
Pyridines/*administration & dosage
Triazoles/*administration & dosage
Administration, Oral ; Adolescent ; Adult ; Antidiuretic Hormone Receptor Antagonists/adverse effects ; Antidiuretic Hormone Receptor Antagonists/pharmacokinetics ; Area Under Curve ; Benzodiazepines/adverse effects ; Benzodiazepines/pharmacokinetics ; Biological Availability ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Half-Life ; Humans ; Male ; Middle Aged ; Pyridines/adverse effects ; Pyridines/pharmacokinetics ; Time Factors ; Tissue Distribution ; Triazoles/adverse effects ; Triazoles/pharmacokinetics ; Young Adult
Czasopismo naukowe
Tytuł :
Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.
Autorzy :
Ericsson H; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Nelander K; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Heijer M; Clinical Pharmacology Biologics and Bioanalysis, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
Kjaer M; Early Biometrics and Statistical Innovation, Data Science & AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Lindstedt EL; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Albayaty M; Parexel, Early Phase Clinical Unit, Harrow, UK.
Forte P; Parexel, Early Phase Clinical Unit, Harrow, UK.
Lagerström-Fermér M; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Skrtic S; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
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Źródło :
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2020 Apr; Vol. 9 (3), pp. 411-421. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Food-Drug Interactions*
5-Lipoxygenase-Activating Protein Inhibitors/*pharmacokinetics
Pyrazoles/*pharmacokinetics
Rosuvastatin Calcium/*pharmacology
5-Lipoxygenase-Activating Protein Inhibitors/administration & dosage ; 5-Lipoxygenase-Activating Protein Inhibitors/pharmacology ; Administration, Oral ; Adult ; Biological Availability ; Cross-Over Studies ; Drug Interactions ; Fasting ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Male ; Middle Aged ; Pyrazoles/administration & dosage ; Pyrazoles/pharmacology ; Rosuvastatin Calcium/administration & dosage ; Young Adult
Czasopismo naukowe
Tytuł :
Exploring the compatibility mechanism of ShengDiHuang Decoction based on the in situ single-pass intestinal perfusion model.
Autorzy :
Yang H; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Hao Q; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Cheng J; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Wang M; Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Zou J; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Zhang X; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
Guo D; Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China.
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Źródło :
Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2020 Feb; Vol. 41 (1-2), pp. 44-53. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Herb-Drug Interactions*
Drugs, Chinese Herbal/*pharmacokinetics
Plant Extracts/*pharmacokinetics
Animals ; Carrier Proteins ; Drug Interactions ; Hydrogen-Ion Concentration ; Male ; Rats ; Rats, Sprague-Dawley ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs.
Autorzy :
Petersen MJ; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bergien SO; The Danish Multiple Sclerosis Society, Valby, Denmark.
Staerk D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Jul; Vol. 35 (7), pp. 3610-3631. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Dietary Supplements*
Herb-Drug Interactions*
Multiple Sclerosis*/drug therapy
Plants, Medicinal*
Ginkgo biloba ; Humans ; Panax
Czasopismo naukowe
Tytuł :
Visualizing Food-Drug Interactions in the Thériaque Database.
Autorzy :
Lalanne F; Univ. Bordeaux, CNRS, LaBRI UMR 5800, F-33000 Bordeaux, France.
Bedouch P; CNHIM, F-75014, Paris, France.; Univ. Grenoble Alpes, CNRS, TIMC UMR 5525, F-38000 Grenoble, France.
Simonnet C; Univ. Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
Depras V; CNHIM, F-75014, Paris, France.
Bordea G; Univ. Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
Bourqui R; Univ. Bordeaux, CNRS, LaBRI UMR 5800, F-33000 Bordeaux, France.
Hamon T; Univ. Paris-Saclay, CNRS, LISN, F-91400 Orsay, France.; Univ. Sorbonne Paris Nord, F-93430 Villetaneuse, France.
Thiessard F; Univ. Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
Mougin F; Univ. Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
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Źródło :
Studies in health technology and informatics [Stud Health Technol Inform] 2021 May 27; Vol. 281, pp. 253-257.
Typ publikacji :
Journal Article
MeSH Terms :
Food-Drug Interactions*
Animals ; Databases, Factual ; Mice
Czasopismo naukowe
Tytuł :
Pharmaceutical consultation to detect drug interactions in patients treated with oral chemotherapies: A descriptive cross-sectional study.
Autorzy :
Lachuer C; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Perrin G; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.; INSERM, UMR 1138, Team 22, Centre de Recherche des Cordeliers (CRC), Université Paris Descartes, Paris, France.
Chastel A; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Aboudagga H; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Thibault C; Department of Medical Oncology, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Delanoy N; Department of Medical Oncology, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Caudron E; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.
Sabatier B; Department of Pharmacy, Hôpital Européen Georges Pompidou, Hôpitaux Universitaires Paris Ouest, Assistance Publique, Hôpitaux de Paris, Paris, France.; INSERM, UMR 1138, Team 22, Centre de Recherche des Cordeliers (CRC), Université Paris Descartes, Paris, France.
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Źródło :
European journal of cancer care [Eur J Cancer Care (Engl)] 2021 May; Vol. 30 (3), pp. e13396. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Interactions*
Pharmaceutical Preparations*
Pharmacists*
Referral and Consultation*
Cross-Sectional Studies ; Humans ; Pilot Projects ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Pharmacokinetic parameters of ifosfamide in mouse pre-administered with grapefruit juice or naringin.
Autorzy :
Madrigal-Bujaidar E; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Av. Wilfrido Massieu s/n, Col. Zacatenco, Del. Gustavo A. Madero, Ciudad de México, 07738, Mexico.
Pérez-Montoya E; Laboratorio de Biofarmacia, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Col. Zacatenco, Del. Gustavo A. Madero, Ciudad de México, 07738, Mexico.
García-Medina S; Laboratorio de Biofarmacia, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu s/n, Col. Zacatenco, Del. Gustavo A. Madero, Ciudad de México, 07738, Mexico.
Cristóbal-Luna JM; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Av. Wilfrido Massieu s/n, Col. Zacatenco, Del. Gustavo A. Madero, Ciudad de México, 07738, Mexico.
Morales-González JA; Laboratorio de Medicina de la Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional. Plan de San Luis y Díaz Mirón s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Ciudad de México, 11340, Mexico.
Madrigal-Santillán EO; Laboratorio de Medicina de la Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional. Plan de San Luis y Díaz Mirón s/n, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Ciudad de México, 11340, Mexico.
Paniagua-Pérez R; Instituto Nacional de Rehabilitación, Servicio de Bioquímica. Av. México-Xochimilco 289, Ciudad de México, 14389, Mexico.
Álvarez-González I; Laboratorio de Genética, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Av. Wilfrido Massieu s/n, Col. Zacatenco, Del. Gustavo A. Madero, Ciudad de México, 07738, Mexico. .
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Źródło :
Scientific reports [Sci Rep] 2019 Nov 12; Vol. 9 (1), pp. 16621. Date of Electronic Publication: 2019 Nov 12.
Typ publikacji :
Journal Article
MeSH Terms :
Food-Drug Interactions*
Antineoplastic Agents/*pharmacokinetics
Citrus paradisi/*adverse effects
Flavanones/*adverse effects
Fruit and Vegetable Juices/*adverse effects
Ifosfamide/*pharmacokinetics
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/blood ; Chromatography, High Pressure Liquid ; Drug Interactions ; Ifosfamide/administration & dosage ; Ifosfamide/blood ; Male ; Mice ; Mice, Inbred ICR
Czasopismo naukowe
Tytuł :
Concomitant Intake of Coca-Cola to Manage the Drug-Drug Interaction Between Velpatasvir and Omeprazole Studied in Healthy Volunteers.
Autorzy :
van Seyen M; Department of Pharmacy, Radboud Institute for Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.
Colbers A; Department of Pharmacy, Radboud Institute for Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.
Abbink EJ; Radboudumc Technology Center Clinical Studies, Radboud University Medical Center, Nijmegen, The Netherlands.
Drenth JPH; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Burger DM; Department of Pharmacy, Radboud Institute for Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2019 Nov; Vol. 106 (5), pp. 1093-1098. Date of Electronic Publication: 2019 Aug 18.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbonated Beverages*
Food-Drug Interactions*
Carbamates/*pharmacokinetics
Heterocyclic Compounds, 4 or More Rings/*pharmacokinetics
Omeprazole/*pharmacology
Sofosbuvir/*pharmacokinetics
Adult ; Area Under Curve ; Cross-Over Studies ; Drug Combinations ; Drug Interactions ; Female ; Healthy Volunteers ; Humans ; Male ; Metabolic Clearance Rate ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Dietary supplement use in ambulatory cancer patients: a survey on prevalence, motivation and attitudes.
Autorzy :
Tank M; Medizinisches Versorgungszentrum Tempelhof Oncology, Berlin, Germany.; Department of Geriatrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
Franz K; Department of Geriatrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Reinickendorfer Str. 61, 13347, Berlin, Germany.; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany.
Cereda E; Clinical Nutrition and Dietetics Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Norman K; Department of Geriatrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Reinickendorfer Str. 61, 13347, Berlin, Germany. .; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany. .; Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany. .
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Jul; Vol. 147 (7), pp. 1917-1925. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Dietary Supplements*
Drug Interactions*
Feeding Behavior*
Ambulatory Care Facilities/*statistics & numerical data
Cancer Care Facilities/*statistics & numerical data
Hematologic Neoplasms/*diet therapy
Aged ; Attitude ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; Hematologic Neoplasms/psychology ; Humans ; Male ; Motivation ; Prevalence ; Prognosis ; Surveys and Questionnaires
Czasopismo naukowe

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