Temat: "Drug Interactions" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Design and statistics of pharmacokinetic drug-drug, herb-drug, and food-drug interaction studies in oncology patients.
Autorzy:: Lanser DAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands. Electronic address: .
Van der Kleij MBA; Department of Medical Oncology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.
Veerman GDM; Department of Medical Oncology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.
Steeghs N; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.
Huitema ADR; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands; Department of Clinical Pharmacy, Utrecht University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands; Department of Pharmacology, Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.
Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.
Oomen-de Hoop E; Department of Medical Oncology, Erasmus MC Cancer Institute, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.; Pokaż więcej
Źródło:: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Jul; Vol. 163, pp. 114823. Date of Electronic Publication: 2023 May 10.
Typ publikacji:: Journal Article
MeSH Terms:: Food-Drug Interactions*
Neoplasms*/drug therapy
Humans ; Drug Interactions ; Herb-Drug Interactions ; Polypharmacy ; Cross-Over Studies

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Szczegóły

Skocz do pozycji: 2.

Tytuł:: Cytochrome P-450-mediated herb and food-drug interactions can be identified in cancer patients through patient self-reporting with a tablet application: results of a prospective observational study.
Autorzy:: Gougis P; Residual Tumor & Response to Treatment Laboratory, RT2Lab, INSERM, U932 Immunity and Cancer, Institut Curie, Université Paris, Paris, France; Sorbonne Université, Institut national de la santé et de la recherche médicale (INSERM), Assistance Publique-Hôpitaux de Paris (AP-HP), Clinical Investigation Center (CIC-1901), Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France. Electronic address: .
Géraud A; Department of Drug Development, Gustave Roussy Cancer Center, Villejuif, France.
Hilmi M; Medical Oncology Department, Curie Institute, Versailles Saint-Quentin University (UVQ), Paris Saclay University, Saint-Cloud, France.
Vozy A; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Campedel L; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Abbar B; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Allio C; Sorbonne Université, Institut national de la santé et de la recherche médicale (INSERM), Assistance Publique-Hôpitaux de Paris (AP-HP), Clinical Investigation Center (CIC-1901), Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
De Chatillon S; Sorbonne Université, Institut national de la santé et de la recherche médicale (INSERM), Assistance Publique-Hôpitaux de Paris (AP-HP), Clinical Investigation Center (CIC-1901), Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Portalier A; Clinical Hematology Unit, Groupe Hospitalier Pitié-Salpêtrière, AP-HP Sorbonne Université, Paris, France.
Lapray F; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Choquet S; Clinical Hematology Unit, Groupe Hospitalier Pitié-Salpêtrière, AP-HP Sorbonne Université, Paris, France.
Spano JP; Department of Medical Oncology, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France.
Reyal F; Residual Tumor & Response to Treatment Laboratory, RT2Lab, INSERM, U932 Immunity and Cancer, Institut Curie, Université Paris, Paris, France; Department of Breast, Gynecological and Reconstructive Surgery, Institut Curie, Université Paris, Paris, France; Department of Surgical Oncology, Institut Godinot, Reims, France.
Mir O; Department of Ambulatory Care, Gustave Roussy Cancer Campus, Villejuif, France.
Funck-Brentano C; Sorbonne Université, Institut national de la santé et de la recherche médicale (INSERM), Assistance Publique-Hôpitaux de Paris (AP-HP), Clinical Investigation Center (CIC-1901), Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France.
Hamy AS; Residual Tumor & Response to Treatment Laboratory, RT2Lab, INSERM, U932 Immunity and Cancer, Institut Curie, Université Paris, Paris, France; Department of Medical Oncology, Institut Curie, Université Paris, Paris, France.; Pokaż więcej
Źródło:: ESMO open [ESMO Open] 2022 Dec; Vol. 7 (6), pp. 100650. Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:: Observational Study; Journal Article
MeSH Terms:: Food-Drug Interactions*
Neoplasms*/drug therapy
Humans ; Prospective Studies ; Herb-Drug Interactions ; Cytochrome P-450 Enzyme System

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Szczegóły

Skocz do pozycji: 3.

Tytuł:: Computer-Aided (In Silico) Modeling of Cytochrome P450-Mediated Food-Drug Interactions (FDI).
Autorzy:: Guttman Y; Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
Kerem Z; Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 31; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cytochrome P-450 Enzyme System*/metabolism
Food-Drug Interactions*
Computers ; Drug Interactions ; Ligands ; Machine Learning

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Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Comprehensive clinical pharmacology characterization of AZD4635 in healthy participants to support dosing considerations.
Autorzy:: Moorthy G; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Boston, Massachusetts, USA.
Pouliot GP; Oncology Research and Development, AstraZeneca, Boston, Massachusetts, USA.
Graham L; Pharmaceutical Sciences, Research and Development, AstraZeneca, Macclesfield, UK.
Pilling E; Oncology Research and Development, AstraZeneca, Cambridge, UK.
Jung L; Oncology Research and Development, AstraZeneca, Cambridge, UK.
Alcobi R; Oncology Research and Development, AstraZeneca, Cambridge, UK.
Zhu Y; Clinical Pharmacology Services, Labcorp Drug Development, Madison, Wisconsin, USA.
Li Y; Clinical Pharmacology & Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Boston, Massachusetts, USA.
Sidhu S; Quotient Sciences, Ruddington, UK.
Forte P; Parexel Early Phase Clinical Unit, London, UK.
Mugundu G; Takeda, Cambridge, Massachusetts, USA.; Pokaż więcej
Źródło:: British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Sep; Vol. 89 (9), pp. 2775-2787. Date of Electronic Publication: 2023 May 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Food-Drug Interactions*
Pharmacology, Clinical*
Humans ; Healthy Volunteers ; Fluvoxamine ; Area Under Curve ; Biological Availability ; Cross-Over Studies ; Administration, Oral

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Szczegóły

Skocz do pozycji: 5.

Tytuł:: Identification of the perpetrator imperatorin in Xin-yi-san-theophylline interaction: observed and predicted herb-drug interaction in rats.
Autorzy:: Wang HJ; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Chen AC; Division of Basic Chinese Medicine, National Research Institute of Chinese Medicine, Taipei, Taiwan.; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chen HY; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Cheng HC; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Kao LT; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Lu CK; Division of Chinese Medicinal Chemistry, National Research Institute of Chinese Medicine, Taipei, Taiwan.; Department of Life Sciences and Institute of Genome Sciences, School of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tsai KC; Division of Chinese Medicinal Chemistry, National Research Institute of Chinese Medicine, Taipei, Taiwan.
Lee IJ; Department of Herbal Medicine, Yokohama University of Pharmacy, Yokohama, Japan.
Ueng YF; Division of Basic Chinese Medicine, National Research Institute of Chinese Medicine, Taipei, Taiwan.; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Pokaż więcej
Źródło:: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2023 Sep 01; Vol. 75 (9), pp. 1225-1236.
Typ publikacji:: Journal Article
MeSH Terms:: Theophylline*/pharmacokinetics
Herb-Drug Interactions*
Rats ; Humans ; Animals ; Fluvoxamine/pharmacology ; Bronchodilator Agents/pharmacokinetics

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Szczegóły

Skocz do pozycji: 6.

Tytuł:: Drug-drug interaction signals between loop diuretics and teicoplanin during acute kidney injury evaluated using Japanese spontaneous adverse drug event reports.
Autorzy:: Hirai T; Department of Pharmacy, Faculty of Medicine, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. .
Kondo Y; Department of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, Kumamoto, 862-0973, Japan.
Sakazaki Y; Department of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, Kumamoto, 862-0973, Japan.
Seki A; Department of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, Kumamoto, 862-0973, Japan.
Ishitsuka Y; Department of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oehonmachi, Chuo-ku, Kumamoto, Kumamoto, 862-0973, Japan.
Iwamoto T; Department of Pharmacy, Faculty of Medicine, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 26; Vol. 13 (1), pp. 13989. Date of Electronic Publication: 2023 Aug 26.
Typ publikacji:: Journal Article
MeSH Terms:: Acute Kidney Injury*/chemically induced
Diuretics*/adverse effects
Drug Interactions*
Drug-Related Side Effects and Adverse Reactions*
Teicoplanin*/adverse effects
Humans ; East Asian People ; Sodium Potassium Chloride Symporter Inhibitors ; Vancomycin/adverse effects ; Japan

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Skocz do pozycji: 7.

Tytuł:: A patient information mining network for drug recommendation.
Autorzy:: Li R; School of Computer Science and Technology, Dalian University of Technology, DaLian, Liaoning, China.
Wang J; School of Computer Science and Technology, Dalian University of Technology, DaLian, Liaoning, China. Electronic address: .
Lin H; School of Computer Science and Technology, Dalian University of Technology, DaLian, Liaoning, China.
Lin Y; Institute of Science and Technology Management, Dalian University of Technology, DaLian, Liaoning, China.
Lu H; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, DaLian, Liaoning, China.
Yang Z; School of Computer Science and Technology, Dalian University of Technology, DaLian, Liaoning, China.; Pokaż więcej
Źródło:: Methods (San Diego, Calif.) [Methods] 2023 Aug; Vol. 216, pp. 3-10. Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Interactions*
Data Mining*
Humans ; Drug Combinations

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Szczegóły

Skocz do pozycji: 8.

Tytuł:: A novel graph mining approach to predict and evaluate food-drug interactions.
Autorzy:: Rahman MM; Department of Computer Science, St. Francis Xavier University, Antigonish, NS, Canada.
Vadrev SM; Department of Computer Science, St. Francis Xavier University, Antigonish, NS, Canada.
Magana-Mora A; Drilling Technology Team, EXPEC Advanced Research Center, Saudi Aramco, Dhahran, 31311, Saudi Arabia.
Levman J; Department of Computer Science, St. Francis Xavier University, Antigonish, NS, Canada. .
Soufan O; Department of Computer Science, St. Francis Xavier University, Antigonish, NS, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 20; Vol. 12 (1), pp. 1061. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Food Analysis*
Food-Drug Interactions*
Pharmaceutical Preparations/*chemistry
Algorithms ; Databases, Factual ; Databases, Pharmaceutical ; Drug Interactions ; Food/classification ; Humans ; Pharmacokinetics

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Skocz do pozycji: 9.

Tytuł:: Evaluation of the Herb-Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents.
Autorzy:: Husain I; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Dale OR; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Idrisi M; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Gurley BJ; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Avula B; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Katragunta K; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Ali Z; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Chittiboyina A; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Noonan G; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration, College Park, Maryland 20740, United States.
Khan IA; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.; Department of Bio-Molecular Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Khan SI; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.; Department of Bio-Molecular Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.; Pokaż więcej
Źródło:: Journal of agricultural and food chemistry [J Agric Food Chem] 2023 May 17; Vol. 71 (19), pp. 7521-7534. Date of Electronic Publication: 2023 May 03.
Typ publikacji:: Journal Article
MeSH Terms:: Herb-Drug Interactions*
Ginger*/chemistry
ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Neoplasm Proteins ; ATP-Binding Cassette Transporters

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Skocz do pozycji: 10.

Tytuł:: Food constituent- and herb-drug interactions in oncology: Influence of quantitative modelling on Drug labelling.
Autorzy:: Pilla Reddy V; Modelling and Simulation, Early Oncology, Oncology R&D, AstraZeneca, Cambridge, UK.; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Jo H; Modelling and Simulation, Early Oncology, Oncology R&D, AstraZeneca, Cambridge, UK.; Certara UK Ltd, Simcyp Division, Sheffield, UK.
Neuhoff S; Certara UK Ltd, Simcyp Division, Sheffield, UK.; Pokaż więcej
Źródło:: British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Oct; Vol. 87 (10), pp. 3988-4000. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Herb-Drug Interactions*
Hypericum*
ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Drug Interactions ; Drug Labeling ; Humans ; Neoplasm Proteins ; Prospective Studies

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Szczegóły

Skocz do pozycji: 11.

Tytuł:: Pharmacokinetic and Pharmacodynamic Interactions Between Henagliflozin, a Novel Selective SGLT-2 Inhibitor, and Warfarin in Healthy Chinese Subjects.
Autorzy:: He X; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Liu G; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Chen X; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Wang Y; Anhui Provincial Center of Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, People's Republic of China.
Liu R; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Wang C; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Huang Y; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China.
Shen J; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China; Anhui Provincial Center of Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, People's Republic of China.
Jia Y; School of Pharmacy, Wannan Medical College, Wuhu, People's Republic of China; Anhui Provincial Center of Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, People's Republic of China. Electronic address: .; Pokaż więcej
Źródło:: Clinical therapeutics [Clin Ther] 2023 Jul; Vol. 45 (7), pp. 655-661. Date of Electronic Publication: 2023 Jul 12.
Typ publikacji:: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Interactions*
Sodium-Glucose Transporter 2 Inhibitors*/adverse effects
Sodium-Glucose Transporter 2 Inhibitors*/pharmacokinetics
Warfarin*/adverse effects
Warfarin*/pharmacokinetics
Bridged Bicyclo Compounds, Heterocyclic*/adverse effects
Bridged Bicyclo Compounds, Heterocyclic*/pharmacokinetics
Humans ; Male ; Area Under Curve ; Cross-Over Studies ; East Asian People ; Healthy Volunteers

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Szczegóły

Skocz do pozycji: 12.

Tytuł:: Streamlining Food Effect Assessment - Are Repeated Food Effect Studies Needed? An IQ Analysis.
Autorzy:: Kesisoglou F; Pharmaceutical Sciences, Merck & Co., Inc., Rahway, NJ, USA. Filippos_.
Basu S; Clinical Pharmacology - Oncology, Novartis Institutes of Biomedical Research, East Hanover, New Jersey, USA.
Belubbi T; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland.
Bransford P; Data & Computational Sciences, Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Chung J; Drug Product Technologies, Amgen Inc., Thousand Oaks, California, USA.
Dodd S; Chemical & Pharmaceutical Profiling, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Dolton M; Roche Products Pty Ltd, Millers Point, NSW, Australia.
Heimbach T; Pharmaceutical Sciences, Merck & Co., Inc., Rahway, NJ, USA.
Kulkarni P; Takeda Pharmaceuticals International, Cambridge, Massachusetts, USA.
Lin W; Pharmacokinetics and Drug Metabolism, Sanofi, Bridgewater, New Jersey, USA.
Moir A; Oral Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, UK.
Parrott N; Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Basel, Switzerland.
Pepin X; New Modalities and Parenteral Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Charter Way, Macclesfield, SK10 2NA, UK.; Regulatory Affairs, Simulations Plus, Lancaster, CA, USA.
Ren X; Modeling & Simulation, PK Sciences, Novartis Institutes of Biomedical Research, East Hanover, New Jersey, USA.
Sharma P; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.
Stamatopoulos K; Biopharmaceutics, DPD, MDS, GSK, David Jack Centre, Park Road, Ware, SG12 0DP, Hertfordshire, UK.
Tistaert C; Pharmaceutical Sciences, Janssen Research & Development, Beerse, Belgium.
Vaidhyanathan S; Drug Product Science and Technology, Bristol-Myers Squibb, New Brunswick, New Jersey, USA.
Wagner C; Global Drug Product Development, Global CMC Development, the Healthcare Business of Merck KGaA, Darmstadt, Germany.
Riedmaier AE; Certara, PBPK Consultancy, Princeton, New Jersey, USA.; Pokaż więcej
Źródło:: The AAPS journal [AAPS J] 2023 Jun 15; Vol. 25 (4), pp. 60. Date of Electronic Publication: 2023 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Models, Biological*
Food-Drug Interactions*
Humans ; Solubility ; Computer Simulation ; Food

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Szczegóły

Skocz do pozycji: 13.

Tytuł:: Effect of a high-fat and high-calorie food on the pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy subjects.
Autorzy:: Wu Q; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Zhu H; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Song R; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Zhang M; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Li F; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China.
Zeng W; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China.
Wang W; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Jia J; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Yu C; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.
Liu Y; Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Shanghai Institute of Clinical Mass Spectrometry, Shanghai, China.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Jun; Vol. 11 (3), pp. e01102.
Typ publikacji:: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Food-Drug Interactions*
Fasting*
Humans ; Healthy Volunteers ; Therapeutic Equivalency ; Biological Availability

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Skocz do pozycji: 14.

Tytuł:: Herb-drug interaction of Xingnaojing injection and Edaravone via pharmacokinetics, mixed inhibition of UGTs, and molecular docking.
Autorzy:: Qi D; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Li H; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Liang C; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Peng P; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yang Z; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Gao Y; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Li Z; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Zhang Q; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Liu Z; Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address: .; Pokaż więcej
Źródło:: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Apr; Vol. 112, pp. 154696. Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:: Journal Article
MeSH Terms:: Herb-Drug Interactions*
Ischemic Stroke*
Rats ; Animals ; Edaravone ; Molecular Docking Simulation ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Glucuronosyltransferase/metabolism

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Szczegóły

Skocz do pozycji: 15.

Tytuł:: Effects of Apigenin on Pharmacokinetics of Dasatinib and Probable Interaction Mechanism.
Autorzy:: Raish M; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ahmad A; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Shahid M; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Jardan YAB; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ahad A; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Kalam MA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ansari MA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Iqbal M; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ali N; Quality Assurance Unit, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alkharfy KM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Jenoobi FI; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 07; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Apigenin*/pharmacology
Dasatinib*/pharmacokinetics
Herb-Drug Interactions*
Animals ; Rats ; Chromatography, Liquid ; Tandem Mass Spectrometry/methods

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Skocz do pozycji: 16.

Tytuł:: Interactions in cancer treatment considering cancer therapy, concomitant medications, food, herbal medicine and other supplements.
Autorzy:: Wolf CPJG; Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany. .
Rachow T; Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Pneumologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Ernst T; Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Konservative Tagesklinik des UniversitätsTumorCentrums (UTC), Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Hochhaus A; Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Zomorodbakhsch B; Onkologische Kooperation Harz, Kösliner Straße 14, 38642, Goslar, Germany.
Foller S; Klinik für Urologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Rengsberger M; Klinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Hartmann M; Apotheke des Universitätsklinikums, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.
Hübner J; Klinik für Innere Medizin II, Hämatologie und Internistische Onkologie, Integrative Onkologie, Universitätsklinikum Jena, Am Klinikum 1, 07747, Jena, Germany.; Pokaż więcej
Źródło:: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2022 Feb; Vol. 148 (2), pp. 461-473. Date of Electronic Publication: 2021 Apr 17.
Typ publikacji:: Journal Article
MeSH Terms:: Dietary Supplements*/adverse effects
Dietary Supplements*/statistics & numerical data
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Food-Drug Interactions/*physiology
Neoplasms/*drug therapy
Plant Extracts/*therapeutic use
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Complementary Therapies/statistics & numerical data ; Drug Interactions ; Female ; Germany/epidemiology ; Herbal Medicine ; Humans ; Male ; Middle Aged ; Neoplasms/epidemiology ; Neoplasms/pathology ; Phytotherapy/adverse effects ; Phytotherapy/methods ; Plants, Medicinal/adverse effects ; Polypharmacy/statistics & numerical data ; Retrospective Studies ; Surveys and Questionnaires ; Young Adult

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Szczegóły

Skocz do pozycji: 17.

Tytuł:: [Prescription errors and drug interactions in adults hospitalized in an intensive care unit in Barranquilla (Colombia).]
Autorzy:: Bohórquez Moreno C; Enfermera Msc Farmacología, Corporación Universitaria Rafael Núñez. Barranquilla. Colombia.
Suárez Rivera M; Enfermera, Corporación Universitaria Rafael Núñez. Barranquilla. Colombia.
Molinares Avila A; Estudiante de enfermería, Corporación Universitaria Rafael Núñez. Barranquilla. Colombia.
Arroyo Gonzalez S; Enfermera, Corporación Universitaria Rafael Núñez. Barranquilla. Colombia.
Madero Zambrano K; Enfermera Msc en Auditoria y sistemas de calidad en servicio de salud, Corporación Universitaria Rafael Núñez.Cartagena. Colombia.; Pokaż więcej
Transliterated Title:: Errores de prescripción e interacciones farmacológicas en personas adultas hospitalizadas en una unidad de cuidados intensivos en Barranquilla (Colombia).
Źródło:: Revista espanola de salud publica [Rev Esp Salud Publica] 2023 Apr 21; Vol. 97. Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:: English Abstract; Journal Article
MeSH Terms:: Drug Interactions*
Medication Errors*/statistics & numerical data
Drug Prescriptions*
Adult ; Humans ; Male ; Colombia ; Intensive Care Units ; Female ; Hospitalization

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Szczegóły

Skocz do pozycji: 18.

Tytuł:: Development and Validation of an Explainable Machine Learning-Based Prediction Model for Drug-Food Interactions from Chemical Structures.
Autorzy:: Kha QH; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; AIBioMed Research Group, Taipei Medical University, Taipei 110, Taiwan.
Le VH; International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; AIBioMed Research Group, Taipei Medical University, Taipei 110, Taiwan.; Department of Thoracic Surgery, Khanh Hoa General Hospital, Nha Trang City 65000, Vietnam.
Hung TNK; Department of Orthopedic and Trauma, Cho Ray Hospital, Ho Chi Minh City 70000, Vietnam.
Nguyen NTK; Undergraduate Program of Nutrition Science, National Taiwan Normal University, Taipei 106, Taiwan.
Le NQK; AIBioMed Research Group, Taipei Medical University, Taipei 110, Taiwan.; Professional Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Research Center for Artificial Intelligence in Medicine, Taipei Medical University, Taipei 110, Taiwan.; Translational Imaging Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan.; Pokaż więcej
Źródło:: Sensors (Basel, Switzerland) [Sensors (Basel)] 2023 Apr 13; Vol. 23 (8). Date of Electronic Publication: 2023 Apr 13.
Typ publikacji:: Journal Article
MeSH Terms:: Food-Drug Interactions*
Drug-Related Side Effects and Adverse Reactions*
Humans ; Artificial Intelligence ; Machine Learning

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Skocz do pozycji: 19.

Tytuł:: A Food-Effect Study to Evaluate the Oral Bioavailability of Desidustat.
Autorzy:: Patel H; Clinical R&D, Zydus Lifesciences Limited, Ahmedabad, India.
Momin T; Clinical R&D, Zydus Therapeutics Inc., Pennington, New Jersey, USA.
Kansagra K; Clinical R&D, Zydus Lifesciences Limited, Ahmedabad, India.
Patel H; DMPK, Zydus Lifesciences Limited, Ahmedabad, India.
Shah C; Clinical R&D, Zydus Lifesciences Limited, Ahmedabad, India.
Barot A; DMPK, Zydus Lifesciences Limited, Ahmedabad, India.
Bhavsar J; Clinical R&D, Zydus Lifesciences Limited, Ahmedabad, India.
Zala K; Clinical R&D, Zydus Lifesciences Limited, Ahmedabad, India.
Parmar D; Clinical R&D, Zydus Therapeutics Inc., Pennington, New Jersey, USA.; Pokaż więcej
Źródło:: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 356-362. Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Food-Drug Interactions*
Fasting*
Adult ; Humans ; Male ; Female ; Biological Availability ; Food

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Szczegóły

Skocz do pozycji: 20.

Tytuł:: Effect of a high-fat meal on the relative bioavailability of HMPL-689 in Chinese healthy volunteers.
Autorzy:: Cao W; Emergency Department, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.
Ding Q; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Wang Y; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Liu S; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Sun S; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Jiang F; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Xu X; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Sai Y; Hutchison Medipharma Ltd., Shanghai, China.
Wang J; Hutchison Medipharma Ltd., Shanghai, China.
Chen Q; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.
Liu Y; Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan - Xuhui Hospital, Fudan University, Shanghai, China.; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China.; Pokaż więcej
Źródło:: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2023 Apr; Vol. 37 (2), pp. 385-391. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:: Journal Article
MeSH Terms:: East Asian People*
Food-Drug Interactions*
Humans ; Male ; Biological Availability ; Healthy Volunteers ; Cross-Over Studies ; Area Under Curve ; Protein Kinase Inhibitors/pharmacokinetics ; Administration, Oral ; Fasting

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