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Wyszukujesz frazę ""Drug Resistance, Viral"" wg kryterium: Temat


Tytuł :
Prevalence of transmitted HIV-1 drug resistance among treatment-naive individuals in China, 2000-2016.
Autorzy :
Yuan H; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.; State Key Laboratory of Genetic Engineering, Human Phenome Institute, and School of Life Sciences, Fudan University, Shanghai, China.
Liu Z; State Key Laboratory of Genetic Engineering, Human Phenome Institute, and School of Life Sciences, Fudan University, Shanghai, China.
Wu X; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.
Wu M; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.
Fang Q; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.
Zhang X; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.
Shi T; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China.
Tully DC; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Zhang T; Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200237, China. .
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Źródło :
Archives of virology [Arch Virol] 2021 Sep; Vol. 166 (9), pp. 2451-2460. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Prevalence*
Anti-HIV Agents/*pharmacology
Drug Resistance, Viral/*drug effects
HIV Infections/*epidemiology
HIV Infections/*transmission
HIV-1/*drug effects
Anti-HIV Agents/therapeutic use ; Anti-Retroviral Agents/therapeutic use ; China/epidemiology ; Drug Resistance, Viral/genetics ; Female ; HIV Infections/drug therapy ; HIV-1/genetics ; Humans ; Male ; Mutation ; Phylogeny
Czasopismo naukowe
Tytuł :
Transmitted drug resistance to Tenofovir/Emtricitabine among persons with newly diagnosed HIV infection in Shenyang city, Northeast China from 2016 to 2018.
Autorzy :
Wang Z; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
Zhao B; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
An M; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
Song W; Department of Food Safety and Nutrition, Shenyang Center for Health Service and Administrative Law Enforcement (Shenyang Center for Disease Control and Prevention), Shenyang, 110031, China.
Dong X; Department of Food Safety and Nutrition, Shenyang Center for Health Service and Administrative Law Enforcement (Shenyang Center for Disease Control and Prevention), Shenyang, 110031, China.
Li X; Department of Food Safety and Nutrition, Shenyang Center for Health Service and Administrative Law Enforcement (Shenyang Center for Disease Control and Prevention), Shenyang, 110031, China.
Wang L; Department of Food Safety and Nutrition, Shenyang Center for Health Service and Administrative Law Enforcement (Shenyang Center for Disease Control and Prevention), Shenyang, 110031, China.
Wang L; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
Tian W; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
Ding H; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China.; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China.; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China.
Han X; National Clinical Research Center for Laboratory Medicine, NHC Key Laboratory of AIDS Immunology (China Medical University), The First Affiliated Hospital of China Medical University, No 155, Nanjing North Street, Heping District, Shenyang, 110001, Liaoning Province, China. .; Key Laboratory of AIDS Immunology, Chinese Academy of Medical Sciences, Shenyang, 110001, China. .; Key Laboratory of AIDS Immunology of Liaoning Province, Shenyang, 110001, China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jul 09; Vol. 21 (1), pp. 668. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral*/genetics
Anti-HIV Agents/*therapeutic use
Emtricitabine/*therapeutic use
HIV Infections/*virology
HIV-1/*drug effects
Tenofovir/*therapeutic use
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; China/epidemiology ; Epidemics ; Female ; Genotype ; HIV Infections/drug therapy ; HIV-1/genetics ; Humans ; Male ; Middle Aged ; Phylogeny ; Reverse Transcriptase Inhibitors/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Novel drug resistance-associated substitutions against pibrentasvir emerged in genotype 1b hepatitis C virus-infected human hepatocyte transplanted mice.
Autorzy :
Ohya K; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Imamura M; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Teraoka Y; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Uchida T; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Fujino H; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Nakahara T; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Ono A; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Murakami E; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Yamauchi M; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Kawaoka T; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Miki D; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Tsuge M; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan.
Abe-Chayama H; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; Center for Medical Specialist Graduate Education and Research, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hayes CN; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Aikata H; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan.
Ishida Y; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; PhoenixBio Co., Ltd., Higashihiroshima, Japan.
Tateno C; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; PhoenixBio Co., Ltd., Higashihiroshima, Japan.
Song H; Laboratory of Tumor Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Miyayama Y; Laboratory of Tumor Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Hijikata M; Laboratory of Tumor Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Chayama K; Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; Institute of Physical and Chemical Research (RIKEN) Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jun 25; Vol. 559, pp. 78-83. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Antiviral Agents/*pharmacology
Benzimidazoles/*pharmacology
Hepacivirus/*drug effects
Hepatitis C/*drug therapy
Pyrrolidines/*pharmacology
Animals ; Antiviral Agents/therapeutic use ; Benzimidazoles/therapeutic use ; Hepacivirus/genetics ; Hepatitis C/virology ; Hepatocytes/virology ; Humans ; Male ; Mice ; Mice, SCID ; Mutation/drug effects ; Pyrrolidines/therapeutic use
Czasopismo naukowe
Tytuł :
HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies.
Autorzy :
Manyana S; National Health Laboratory Service, Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4058, South Africa.
Gounder L; National Health Laboratory Service, Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4058, South Africa.
Pillay M; National Health Laboratory Service, Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4058, South Africa.
Manasa J; Department of Laboratory Medicine and Investigative Sciences, Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Naidoo K; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban 4013, South Africa.; South African Medical Research Council (SAMRC), CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Durban 4013, South Africa.
Chimukangara B; National Health Laboratory Service, Department of Virology, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4058, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban 4013, South Africa.
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Źródło :
Viruses [Viruses] 2021 Jun 11; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Genotype*
HIV Infections/*virology
HIV-1/*drug effects
HIV-1/*genetics
Anti-HIV Agents/pharmacology ; Anti-HIV Agents/therapeutic use ; Genotyping Techniques ; HIV Infections/drug therapy ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation
Czasopismo naukowe
Tytuł :
High Detection Rate of HIV Drug Resistance Mutations among Patients Who Fail Combined Antiretroviral Therapy in Manaus, Brazil.
Autorzy :
Chaves YO; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.
Pereira FR; Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus, Amazonas CEP 69040-000, Brazil.
de Souza Pinheiro R; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.
Batista DRL; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.
da Silva Balieiro AA; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.
de Lacerda MVG; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.; Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus, Amazonas CEP 69040-000, Brazil.
Nogueira PA; Laboratório de Diagnóstico e Controle de Doenças Infecciosas na Amazônia (DCDIA), Instituto Leônidas e Maria Deane (ILMD)-Fiocruz Amazônia, Manaus CEP 69.057-070, Brazil.; Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus, Amazonas CEP 69040-000, Brazil.
Guimarães ML; Laboratório de AIDS e Imunologia Molecular, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ CEP 21040-900, Brazil.
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Źródło :
BioMed research international [Biomed Res Int] 2021 Jun 08; Vol. 2021, pp. 5567332. Date of Electronic Publication: 2021 Jun 08 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Anti-HIV Agents/*therapeutic use
Anti-Retroviral Agents/*therapeutic use
Drug Resistance, Viral/*genetics
HIV Infections/*drug therapy
HIV Infections/*virology
Mutation/*genetics
Adult ; Brazil ; Cross-Sectional Studies ; Drug Resistance, Viral/drug effects ; Female ; HIV Infections/genetics ; HIV-1/drug effects ; Humans ; Male ; Middle Aged ; Reverse Transcriptase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Favipiravir-resistant influenza A virus shows potential for transmission.
Autorzy :
Goldhill DH; Department of Infectious Disease, Imperial College, London, United Kingdom.
Yan A; Department of Infectious Disease Epidemiology, Imperial College, London, United Kingdom.
Frise R; Department of Infectious Disease, Imperial College, London, United Kingdom.
Zhou J; Department of Infectious Disease, Imperial College, London, United Kingdom.
Shelley J; Department of Infectious Disease, Imperial College, London, United Kingdom.
Gallego Cortés A; Department of Infectious Disease, Imperial College, London, United Kingdom.
Miah S; Public Health England, London, United Kingdom.
Akinbami O; Public Health England, London, United Kingdom.
Galiano M; Public Health England, London, United Kingdom.
Zambon M; Public Health England, London, United Kingdom.
Lackenby A; Public Health England, London, United Kingdom.
Barclay WS; Department of Infectious Disease, Imperial College, London, United Kingdom.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Jun 01; Vol. 17 (6), pp. e1008937. Date of Electronic Publication: 2021 Jun 01 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amides/*pharmacology
Antiviral Agents/*pharmacology
Drug Resistance, Viral/*genetics
Influenza A Virus, H1N1 Subtype/*genetics
Orthomyxoviridae Infections/*genetics
Orthomyxoviridae Infections/*transmission
Pyrazines/*pharmacology
Animals ; Drug Resistance, Viral/drug effects ; Ferrets ; Humans ; Influenza, Human/virology
Czasopismo naukowe
Tytuł :
Nationwide Study of Drug Resistance Mutations in HIV-1 Infected Individuals under Antiretroviral Therapy in Brazil.
Autorzy :
Santos-Pereira A; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.
Triunfante V; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.
Araújo PMM; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.
Martins J; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.
Soares H; Human Immunobiology and Pathogenesis Laboratory, 1150-082 Lisbon, Portugal.; CEDOC-Chronic Diseases Research Center, NOVA Medical School, Faculdade de Ciências Médicas, NOVA University of Lisbon, 1150-082 Lisbon, Portugal.
Poveda E; Group of Virology and Pathogenesis, Galicia Sur Health Research Institute (IIS Galicia Sur)-Complexo Hospitalario Universitario de Vigo, SERGAS-UVigo, 36213 Vigo, Spain.
Souto B; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.; Department of Medicine, Federal University of São Carlos, São Paulo 13565-905, Brazil.
Osório NS; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.; ICVS/3B's-PT Government Associate Laboratory, 4710-057 Braga, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 18; Vol. 22 (10). Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral/*genetics
HIV Infections/*genetics
Adenine/therapeutic use ; Adult ; Aged ; Anti-HIV Agents/pharmacology ; Brazil/epidemiology ; Drug Resistance, Viral/physiology ; Female ; HIV Infections/drug therapy ; HIV Reverse Transcriptase/genetics ; HIV-1/drug effects ; HIV-1/genetics ; HIV-1/pathogenicity ; Humans ; Male ; Middle Aged ; Mutation/drug effects ; Reverse Transcriptase Inhibitors/pharmacology ; Tenofovir/therapeutic use ; Treatment Failure ; Viral Load/drug effects ; Zidovudine/therapeutic use
Czasopismo naukowe
Tytuł :
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model.
Autorzy :
Lee LY; WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
Zhou J; Department of Infectious Disease, Imperial College London, London, United Kingdom.
Koszalka P; WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Biomedicine Discovery Institute & Department of Microbiology, Monash University, Victoria, Australia.
Frise R; Department of Infectious Disease, Imperial College London, London, United Kingdom.
Farrukee R; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia.
Baba K; Shionogi & Co., Ltd, Osaka, Japan.
Miah S; Public Health England, London, United Kingdom.
Shishido T; Shionogi & Co., Ltd, Osaka, Japan.
Galiano M; Francis Crick Institute, London, United Kingdom.
Hashimoto T; Shionogi & Co., Ltd, Osaka, Japan.
Omoto S; Shionogi & Co., Ltd, Osaka, Japan.
Uehara T; Shionogi & Co., Ltd, Osaka, Japan.
Mifsud EJ; WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia.
Collinson N; Roche Products Ltd, Welwyn Garden City, United Kingdom.
Kuhlbusch K; F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Clinch B; Roche Products Ltd, Welwyn Garden City, United Kingdom.
Wildum S; F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Barclay WS; Department of Infectious Disease, Imperial College London, London, United Kingdom.
Hurt AC; WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia.; F. Hoffmann-La Roche Ltd, Basel, Switzerland.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 May 06; Vol. 17 (5), pp. e1009527. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Drug Resistance, Viral*
Virus Replication*
Antiviral Agents/*pharmacology
Dibenzothiepins/*pharmacology
Influenza A virus/*genetics
Morpholines/*pharmacology
Orthomyxoviridae Infections/*drug therapy
Pyridones/*pharmacology
Triazines/*pharmacology
Amino Acid Substitution ; Animals ; Female ; Ferrets ; Influenza A virus/drug effects ; Influenza A virus/isolation & purification ; Male ; Orthomyxoviridae Infections/virology
Czasopismo naukowe
Tytuł :
Primary resistance to antiretroviral drugs of HIV strains in Chad: a retrospective investigation by analysis of frozen dried blood spot samples.
Autorzy :
Keita A; Institut National de Recherche en Santé Publique, Bamako, Mali.
Djimera N; Service de Maladies infectieuses, Hôpital Le Bon Samaritain, CHU Walia, N'Djamena, Chad.
Djarma O; Service de Maladies infectieuses, Hôpital Le Bon Samaritain, CHU Walia, N'Djamena, Chad.
N'Guyen Y; Service de Médecine interne, Maladies infectieuses et Immunologie Clinique, Hôpital Robert Debré, CHU Reims, Reims, France.; Laboratoire de Virologie médicale et moléculaire, Hôpital Robert Debré CHU Reims & EA-4684, Faculté de Médecine, Université Reims Champagne Ardennes, Reims, France.
Bourlet T; EA 3064, Faculté de Médecine, Université Jean Monnet, Saint-Etienne, France.
Andreoletti L; Service de Maladies infectieuses, Hôpital Le Bon Samaritain, CHU Walia, N'Djamena, Chad. .; Laboratoire de Virologie médicale et moléculaire, Hôpital Robert Debré CHU Reims & EA-4684, Faculté de Médecine, Université Reims Champagne Ardennes, Reims, France. .
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Źródło :
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2021 May; Vol. 40 (5), pp. 1091-1095. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral*
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
HIV Infections/*virology
HIV-1/*drug effects
Adolescent ; Adult ; Anti-HIV Agents/pharmacology ; Chad/epidemiology ; Female ; HIV Infections/epidemiology ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Viral Load ; Young Adult
Czasopismo naukowe
Tytuł :
Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS).
Autorzy :
Roosenhoff R; Department of Viroscience, Erasmus Medical Center, Rotterdam, 3015GE, the Netherlands.
Schutten M; Clinical Virology and Diagnostics, 1817HL, Alkmaar, the Netherlands.
Reed V; Micron, Ely, CB7 4AF, United Kingdom.
Clinch B; Roche Products Ltd, Welwyn Garden City, AL7 1TW, United Kingdom.
van der Linden A; Department of Viroscience, Erasmus Medical Center, Rotterdam, 3015GE, the Netherlands.
Fouchier RAM; Department of Viroscience, Erasmus Medical Center, Rotterdam, 3015GE, the Netherlands.
Fraaij PLA; Department of Viroscience, Erasmus Medical Center, Rotterdam, 3015GE, the Netherlands; Department of Pediatrics, Subdivision Infectious Diseases and Immunology, Erasmus Medical Center - Sophia, Rotterdam, the Netherlands. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2021 May; Vol. 189, pp. 105060. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Antiviral Agents/*pharmacology
Hemagglutinins/*genetics
Influenza, Human/*virology
Neuraminidase/*genetics
Orthomyxoviridae/*drug effects
Orthomyxoviridae/*genetics
Amino Acid Substitution ; Enzyme Inhibitors/pharmacology ; Genetic Fitness ; Humans ; Influenza A Virus, H3N2 Subtype/drug effects ; Influenza A Virus, H3N2 Subtype/genetics ; Influenza, Human/drug therapy ; Mutation, Missense ; Oseltamivir/pharmacology ; Prospective Studies ; RNA, Viral ; Viral Proteins
Czasopismo naukowe
Tytuł :
Antivirals Targeting the Surface Glycoproteins of Influenza Virus: Mechanisms of Action and Resistance.
Autorzy :
Bai Y; State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, 195 Dongfengxi Rd, Guangzhou 510182, China.
Jones JC; Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
Wong SS; State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, 195 Dongfengxi Rd, Guangzhou 510182, China.; School of Public Health, The University of Hong Kong, Hong Kong, China.
Zanin M; State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, 195 Dongfengxi Rd, Guangzhou 510182, China.; School of Public Health, The University of Hong Kong, Hong Kong, China.
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Źródło :
Viruses [Viruses] 2021 Apr 06; Vol. 13 (4). Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Resistance, Viral*
Antiviral Agents/*pharmacology
Orthomyxoviridae/*drug effects
Viral Envelope Proteins/*antagonists & inhibitors
Animals ; Antiviral Agents/classification ; Antiviral Agents/metabolism ; Clinical Trials as Topic ; Enzyme Inhibitors/pharmacology ; Hemagglutinins, Viral/metabolism ; Humans ; Influenza, Human/drug therapy ; Mice ; Neuraminidase/antagonists & inhibitors ; Orthomyxoviridae/chemistry ; Orthomyxoviridae/classification ; Orthomyxoviridae/enzymology ; Orthomyxoviridae Infections/drug therapy ; Oseltamivir/pharmacology
Czasopismo naukowe
Tytuł :
The impact of routine HIV drug resistance testing in Ontario: A controlled interrupted time series study.
Autorzy :
Mbuagbaw L; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.; Biostatistics Unit, Father Sean O'Sullivan Research Centre, St Joseph's Healthcare, Hamilton, ON, Canada.; Centre for Development of Best Practices in Health (CDBPH), Yaoundé Central Hospital, Yaoundé, Cameroon.
Logie CH; Women's College Research, Toronto, ON, Canada.; Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada.
Thabane L; Departments of Paediatrics and Anaesthesia, McMaster University, Hamilton, ON, Canada.; Centre for Evaluation of Medicine, St Joseph's Healthcare, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton Health Sciences, Hamilton, ON, Canada.
Smaill F; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Smieja M; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Burchell AN; Department of Family and Community Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Family and Community Medicine and Centre for Research on Inner City Health, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Rachlis B; Division of Clinical Public Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Tarride JE; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.; McMaster Chair in Health Technology Management, McMaster University, Hamilton, ON, Canada.
Kroch A; Ontario HIV Treatment Network, Toronto, Ontario, Canada.
Mazzulli T; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Microbiology, Sinai Health System/University Health Network, Toronto, Ontario, Canada.; Public Health Ontario Laboratory, Ontario, Canada.
Alvarez E; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.; Centre for Health Economics and Policy Analysis (CHEPA), McMaster University, Hamilton, Ontario, Canada.
Lawson DO; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Nguyen F; ICES McMaster, McMaster University, Hamilton, Ontario, Canada.
Perez R; ICES McMaster, McMaster University, Hamilton, Ontario, Canada.
Seow H; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.; Department of Oncology, McMaster University, Juravinski Cancer Centre, Hamilton, ON, Canada.
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Źródło :
PloS one [PLoS One] 2021 Apr 02; Vol. 16 (4), pp. e0246766. Date of Electronic Publication: 2021 Apr 02 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
Adult ; Anti-HIV Agents/pharmacology ; Female ; HIV/drug effects ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; Hospitalization ; Humans ; Interrupted Time Series Analysis ; Male ; Middle Aged ; Ontario/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivir.
Autorzy :
Martin R; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA. Electronic address: .
Li J; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Parvangada A; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Perry J; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Cihlar T; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Mo H; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Porter D; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
Svarovskaia E; Gilead Sciences, 333 Lakeside Dr, Foster City, CA, USA.
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Źródło :
Antiviral research [Antiviral Res] 2021 Apr; Vol. 188, pp. 105033. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral*
Genetic Variation*
RNA, Viral*
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
COVID-19/*virology
SARS-CoV-2/*drug effects
SARS-CoV-2/*genetics
Virus Replication/*genetics
Adenosine Monophosphate/pharmacology ; Alanine/pharmacology ; Amino Acid Substitution ; Animals ; COVID-19/drug therapy ; COVID-19/epidemiology ; Evolution, Molecular ; Humans ; Mink ; Models, Molecular ; Protein Conformation ; SARS-CoV-2/classification ; SARS-CoV-2/isolation & purification ; Sequence Analysis, DNA ; Structure-Activity Relationship ; Viral Nonstructural Proteins/chemistry ; Viral Nonstructural Proteins/genetics ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Transmitted drug resistance among HIV-1 drug-naïve patients in Greece.
Autorzy :
Kantzanou M; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece; National Retrovirus Reference Center/NRRC, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece.
Karalexi MA; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece. Electronic address: .
Papachristou H; National Retrovirus Reference Center/NRRC, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece.
Vasilakis A; National Retrovirus Reference Center/NRRC, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece.
Rokka C; National Retrovirus Reference Center/NRRC, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece.
Katsoulidou A; National Retrovirus Reference Center/NRRC, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias, 11527, Goudi, Athens, Greece.
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Apr; Vol. 105, pp. 42-48. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral*/genetics
Anti-HIV Agents/*pharmacology
HIV Infections/*drug therapy
HIV Infections/*virology
HIV-1/*drug effects
Adult ; Anti-HIV Agents/therapeutic use ; Female ; Genotype ; Greece/epidemiology ; HIV Infections/epidemiology ; HIV Seropositivity/drug therapy ; Humans ; Male ; Middle Aged ; Mutation/drug effects ; Prevalence
Czasopismo naukowe
Tytuł :
Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs-First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor.
Autorzy :
Lingappa JR; Department of Global Health, University of Washington, Seattle, WA 98109, USA.
Lingappa VR; Prosetta Biosciences, 670 5th Street, San Francisco, CA 94107, USA.
Reed JC; Department of Global Health, University of Washington, Seattle, WA 98109, USA.
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Źródło :
Viruses [Viruses] 2021 Mar 10; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Resistance, Viral*
Anti-Retroviral Agents/*pharmacology
HIV-1/*drug effects
Host Microbial Interactions/*drug effects
Virus Assembly/*drug effects
Anti-Retroviral Agents/isolation & purification ; Capsid/metabolism ; HIV Seropositivity ; HIV-1/physiology ; Humans ; T-Lymphocytes/drug effects ; T-Lymphocytes/virology
Czasopismo naukowe
Tytuł :
Simulating HIV Breakthrough and Resistance Development During Variable Adherence to Antiretroviral Treatment.
Autorzy :
Mulato A; Gilead Sciences, Inc., Foster City, CA.
Acosta R
Chang S
Martin R
Yant SR
Cihlar T
White K
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Źródło :
Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2021 Mar 01; Vol. 86 (3), pp. 369-377.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Medication Adherence*
Anti-HIV Agents/*administration & dosage
HIV Infections/*drug therapy
HIV-1/*drug effects
Cell Line ; Humans ; T-Lymphocytes/drug effects ; T-Lymphocytes/virology
Czasopismo naukowe
Tytuł :
Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa.
Autorzy :
Obasa AE; Department of Pathology, Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, 7505, South Africa. .; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden. .
Ambikan AT; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.
Gupta S; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.
Neogi U; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.
Jacobs GB; Department of Pathology, Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, 7505, South Africa.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Feb 25; Vol. 21 (1), pp. 214. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Viral/*genetics
HIV Infections/*drug therapy
HIV Protease Inhibitors/*therapeutic use
HIV-1/*drug effects
Quasispecies/*drug effects
Anti-Retroviral Agents/therapeutic use ; Drug Resistance, Viral/drug effects ; Genes, pol/genetics ; Genotype ; HIV Infections/virology ; HIV-1/genetics ; HIV-1/isolation & purification ; Humans ; Mutation ; Quasispecies/genetics ; RNA, Viral/genetics ; South Africa/epidemiology
Czasopismo naukowe
Tytuł :
Next Generation Sequencing for HIV-1 Drug Resistance Testing-A Special Issue Walkthrough.
Autorzy :
Kantor R; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, RI 02906, USA.
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Źródło :
Viruses [Viruses] 2021 Feb 22; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Resistance, Viral*
HIV Infections/*virology
HIV-1/*genetics
Anti-HIV Agents/pharmacology ; HIV-1/classification ; HIV-1/drug effects ; HIV-1/isolation & purification ; High-Throughput Nucleotide Sequencing ; Humans
Raport
Tytuł :
Prevalence of drug resistance mutations in HIV-infected individuals with low-level viraemia under combination antiretroviral therapy: an observational study in a tertiary hospital in Northern Taiwan, 2017-19.
Autorzy :
Kao SW; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Liu ZH; Department of Neurosurgery, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Wu TS; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ku SW; Division of Infectious Diseases, Department of Medicine, Taipei City Hospital Ren-Ai Branch, Taipei, Taiwan.; Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Tsai CL; Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Shie SS; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Huang PY; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Wu YM; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Hsiao YH; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chen NY; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Linkou Branch, Chang Gung University College of Medicine, Taoyuan, Taiwan.
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Źródło :
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2021 Feb 11; Vol. 76 (3), pp. 722-728.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/therapeutic use
Drug Resistance, Viral*/genetics
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV-1*/genetics
Humans ; Mutation ; Prevalence ; Taiwan/epidemiology ; Tertiary Care Centers ; Viral Load ; Viremia/drug therapy ; Viremia/epidemiology
Czasopismo naukowe
Tytuł :
High-throughput sequencing reveals a high prevalence of pretreatment HIV-1 drug resistance in Sweden.
Autorzy :
Andersson E; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute.; Department of Clinical Microbiology, Karolinska University Hospital.
Ambikan A; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute.
Brännström J; Division of Infection and Dermatology, Department of Medicine Huddinge, Karolinska Institute.; Department of Infectious Diseases/Venhälsan, South Hospital, Stockholm.
Aralaguppe SG; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute.
Yilmaz A; Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg.
Albert J; Department of Clinical Microbiology, Karolinska University Hospital.; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm.
Neogi U; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute.
Sönnerborg A; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute.; Department of Clinical Microbiology, Karolinska University Hospital.; Division of Infection and Dermatology, Department of Medicine Huddinge, Karolinska Institute.; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
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Źródło :
AIDS (London, England) [AIDS] 2021 Feb 02; Vol. 35 (2), pp. 227-234.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/therapeutic use
Drug Resistance, Viral*
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV-1*/drug effects
HIV-1*/genetics
Africa South of the Sahara ; Asia ; Cross-Sectional Studies ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation/drug effects ; Prevalence ; Sweden/epidemiology
Czasopismo naukowe

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