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Tytuł:
Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians.
Autorzy:
Kiros M; Department of Medical Laboratory Science, College of Medicine and Health Sciences, Aksum University, Aksum, Ethiopia. .
Tefera DA; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Andualem H; Department of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Geteneh A; Department of Medical Laboratory Science, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Tesfaye A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Woldemichael TS; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Kidane E; The Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Alemayehu DH; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Maier M; Department Virology, Institute Medical Microbiology and Virology, Leipzig University, Leipzig, Germany.
Mihret A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Abegaz WE; Department of Microbiology, Parasitology, and Immunology, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Mulu A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
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Źródło:
Scientific reports [Sci Rep] 2023 Apr 21; Vol. 13 (1), pp. 6546. Date of Electronic Publication: 2023 Apr 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Viral*/drug effects
Drug Resistance, Viral*/genetics
HIV Infections*/drug therapy
HIV Infections*/genetics
HIV Infections*/virology
HIV Integrase*/drug effects
HIV Integrase*/genetics
HIV Integrase*/isolation & purification
HIV Integrase Inhibitors*/pharmacology
HIV Integrase Inhibitors*/therapeutic use
HIV-1*/drug effects
HIV-1*/genetics
HIV-1*/isolation & purification
Drug Resistance, Neoplasm*/drug effects
Drug Resistance, Neoplasm*/genetics
Humans ; Cross-Sectional Studies ; Genotype ; HIV Seropositivity/drug therapy ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The association between HIV pretreatment drug resistance and virological outcomes in children and adults in sub-Saharan Africa: A systematic review and meta-analysis.
Autorzy:
Takem EN; Centers for Disease Control and Prevention (CDC), Cameroon.
Coox C; Centers for Disease Control and Prevention (CDC), Cameroon.
Shang J; Centers for Disease Control and Prevention (CDC), Cameroon.
Ndongmo C; Centers for Disease Control and Prevention (CDC), Cameroon.
Dokubo EK; Centers for Disease Control and Prevention (CDC), Cameroon.
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Źródło:
PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0300456. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV-1*
Adult ; Child ; Humans ; Anti-Retroviral Agents/therapeutic use ; Africa South of the Sahara/epidemiology ; Drug Resistance, Viral ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV protease resistance mutations in patients receiving second-line antiretroviral therapy in Libreville, Gabon.
Autorzy:
Nzengui-Nzengui GF; Département de Bactériologie- Virologie, Laboratoire National de Référence IST/VIH/Sida, Université des Sciences de la Santé, Libreville, Gabon.
Mourembou G; Département de Bactériologie- Virologie, Laboratoire National de Référence IST/VIH/Sida, Université des Sciences de la Santé, Libreville, Gabon.
M'boyis-Kamdem H; Département de Bactériologie- Virologie, Laboratoire National de Référence IST/VIH/Sida, Université des Sciences de la Santé, Libreville, Gabon.
Kombila-Koumavor AC; Département de Bactériologie- Virologie, Laboratoire National de Référence IST/VIH/Sida, Université des Sciences de la Santé, Libreville, Gabon.
Ndjoyi-Mbiguino A; Département de Bactériologie- Virologie, Laboratoire National de Référence IST/VIH/Sida, Université des Sciences de la Santé, Libreville, Gabon. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Mar 14; Vol. 24 (1), pp. 316. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
HIV Infections*/drug therapy
HIV-1*/genetics
Male ; Humans ; Female ; Reverse Transcriptase Inhibitors/therapeutic use ; HIV Protease/genetics ; Gabon ; Anti-Retroviral Agents/therapeutic use ; Protease Inhibitors/therapeutic use ; Mutation ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses.
Autorzy:
Gaymard A; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
Picard C; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.
Vazzoler G; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.
Massin P; Avian and Rabbit Virology Immunology and Parasitology Unit, National Reference Laboratory for Avian Influenza, Anses, Ploufragan-Plouzané-Niort Laboratory, BP53, F-22440 Ploufragan, France.
Frobert E; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
Sabatier M; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.
Barthelemy M; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.
Valette M; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
Ottmann M; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.
Casalegno JS; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
Lina B; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
Escuret V; Virpath Unit, CIRI, Inserm U1111, CNRS, UMR5308, ENS Lyon, Université Claude Bernard Lyon 1, F-69372 Lyon, France.; Centre National de Référence des Virus des Infections Respiratoires, Groupement Hospitalier Nord, Hospices Civils de Lyon, F-69317 Lyon CEDEX 04, France.
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Źródło:
Viruses [Viruses] 2024 Mar 01; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Influenza A virus*/genetics
Influenza A Virus, H1N1 Subtype*/genetics
Influenza, Human*
Humans ; Oseltamivir/pharmacology ; Antiviral Agents/pharmacology ; Neuraminidase/genetics ; Neuraminidase/metabolism ; Reverse Genetics ; Drug Resistance, Viral/genetics ; Amino Acid Substitution ; Enzyme Inhibitors/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis.
Autorzy:
Ouyang F; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.
Yuan D; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.
Zhai W; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.
Liu S; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.
Zhou Y; Department of HIV/STD Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Yang H; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.; Jiangsu Health Development Research Center, Nanjing 210029, China.
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Źródło:
Viruses [Viruses] 2024 Feb 02; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
HIV-1*/genetics
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV Seropositivity*
Humans ; Genotype ; Drug Resistance, Viral/genetics ; High-Throughput Nucleotide Sequencing/methods ; Prevalence ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of ART effects and drug resistance in adult HIV/AIDS patients in Meigu County, Liangshan Prefecture, China.
Autorzy:
Yuan L; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Chen K; Meigu County People's Hospital, Meigu, Liangshan Prefecture, Sichuan, China.
Cai Y; Meigu County People's Hospital, Meigu, Liangshan Prefecture, Sichuan, China.
Zhou Z; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Yang J; Meigu County People's Hospital, Meigu, Liangshan Prefecture, Sichuan, China.
Jiqu W; Meigu County People's Hospital, Meigu, Liangshan Prefecture, Sichuan, China.
Zhu Q; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Zhang H; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Niu S; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Sun H; Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 01; Vol. 24 (1), pp. 155. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Acquired Immunodeficiency Syndrome*/drug therapy
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV-1*/genetics
Nucleic Acids*
Adult ; Humans ; Emtricitabine/therapeutic use ; Nevirapine/pharmacology ; Nevirapine/therapeutic use ; Didanosine ; Mutation ; Drug Resistance ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A strategy for evaluating potential antiviral resistance to small molecule drugs and application to SARS-CoV-2.
Autorzy:
Sargsyan K; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan. .
Mazmanian K; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan. .
Lim C; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 10; Vol. 13 (1), pp. 502. Date of Electronic Publication: 2023 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
SARS-CoV-2*/drug effects
SARS-CoV-2*/genetics
Drug Resistance, Viral*/genetics
Humans ; COVID-19 ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prevalence of acquired and transmitted HIV drug resistance in Iran: a systematic review and meta-analysis.
Autorzy:
Mirzaei H; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.
Eybpoosh S; Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Mehrabi F; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.
Shojaei MR; Department of Microbiology and Virology, Kerman University of Medical Science, Kerman, Iran.
Mirzazadeh A; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.; Department of Epidemiology and Biostatistics, Institute for Global Health Sciences, University of California, San Francisco, USA.
Khezri M; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.; Department of Epidemiology, New York University School of Global Public Health, New York, NY, USA.
Nasiri N; School of Health, Jiroft University of Medical Sciences, Jiroft, Iran.
Sharifi H; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran. .; Affiliate, Institute for Global Health Sciences, University of California San Francisco, San Francisco, CA, USA. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Jan 02; Vol. 24 (1), pp. 29. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
HIV-1*
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
Humans ; Iran/epidemiology ; Reverse Transcriptase Inhibitors/therapeutic use ; Prevalence ; Drug Resistance, Viral ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Comprehensive Literature Review of Treatment-Emergent Integrase Resistance with Dolutegravir-Based Regimens in Real-World Settings.
Autorzy:
Henegar C; ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.
Letang E; ViiV Healthcare, P.T.M., Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
Wang R; ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.
Hicks C; ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.
Fox D; ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.
Jones B; ViiV Healthcare, 980 Great West Road, Brentford TW8 9GS, Middlesex, UK.
de Ruiter A; ViiV Healthcare, 980 Great West Road, Brentford TW8 9GS, Middlesex, UK.
Vannappagari V; ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.
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Źródło:
Viruses [Viruses] 2023 Dec 14; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Integrase Inhibitors*/pharmacology
HIV Integrase Inhibitors*/therapeutic use
HIV Integrase*/genetics
HIV Infections*/drug therapy
Humans ; Heterocyclic Compounds, 3-Ring/pharmacology ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Drug Resistance, Viral/genetics ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022.
Autorzy:
Planinić A; Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Dr. Fran Mihaljević, 10000 Zagreb, Croatia.
Begovac J; School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Rokić F; Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Šimičić P; Department of Oncology and Nuclear Medicine, Sestre Milosrdnice University Hospital Center, 10000 Zagreb, Croatia.
Oroz M; Cytogenetic Laboratory, Department of Obstetrics and Gynecology, Clinical Hospital Sveti Duh, 10000 Zagreb, Croatia.
Jakovac K; Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Vugrek O; Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Zidovec-Lepej S; Department of Immunological and Molecular Diagnostics, University Hospital for Infectious Diseases Dr. Fran Mihaljević, 10000 Zagreb, Croatia.
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Źródło:
Viruses [Viruses] 2023 Dec 11; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Croatia/epidemiology ; Phylogeny ; Genotype ; Drug Resistance, Viral/genetics ; Mutation ; Prevalence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Discovery of Indole-2-carboxylic Acid Derivatives as Novel HIV-1 Integrase Strand Transfer Inhibitors.
Autorzy:
Wang YC; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.; Center for Tissue Engineering and Stem Cell Research, Key Laboratory of Regenerative Medicine of Guizhou Province, School of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.; School of Pharmacy, Guizhou Medical University, Guian New District, Guiyang 550025, China.
Zhang WL; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.; School of Pharmacy, Guizhou Medical University, Guian New District, Guiyang 550025, China.
Zhang RH; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.; Center for Tissue Engineering and Stem Cell Research, Key Laboratory of Regenerative Medicine of Guizhou Province, School of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Liu CH; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.
Zhao YL; School of Pharmacy, Guizhou Medical University, Guian New District, Guiyang 550025, China.
Yan GY; School of Pharmacy, Xinxiang University, Xinxiang 453000, China.
Liao SG; School of Pharmacy, Guizhou Medical University, Guian New District, Guiyang 550025, China.
Li YJ; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.
Zhou M; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang 550004, China.; School of Pharmacy, Guizhou Medical University, Guian New District, Guiyang 550025, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 08; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Integrase Inhibitors*/pharmacology
HIV Integrase Inhibitors*/chemistry
HIV-1*
HIV Integrase*/metabolism
HIV Infections*/drug therapy
Humans ; Molecular Docking Simulation ; Indoles/pharmacology ; Indoles/therapeutic use ; Catalytic Domain ; Drug Resistance, Viral ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differences in drug resistance of HIV-1 genotypes in CSF and plasma and analysis of related factors.
Autorzy:
Wang J; Central lab, Chongqing Public Health Medical Center, Chongqing, China.
Li M; Central lab, Chongqing Public Health Medical Center, Chongqing, China.
Li J; Central lab, Chongqing Public Health Medical Center, Chongqing, China.
Deng R; Central lab, Chongqing Public Health Medical Center, Chongqing, China.
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Źródło:
Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2171632.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
Humans ; Quality of Life ; Drug Resistance, Viral/genetics ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Prevalence and analysis of acquired and transmitted integrase strand transfer inhibitor-associated HIV-1 drug resistance in Chongqing, China.
Autorzy:
Zhang H; Central Laboratory, Chongqing Public Health Medical Center, Chongqing, China.
Wu P; Department of Tuberculosis, Chongqing Public Health Medical Center, Chongqing, China.
Li J; Central Laboratory, Chongqing Public Health Medical Center, Chongqing, China.
Li M; Central Laboratory, Chongqing Public Health Medical Center, Chongqing, China.
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Źródło:
Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2278254. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/genetics
HIV Integrase Inhibitors*/pharmacology
HIV Integrase Inhibitors*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV Integrase*/genetics
HIV Integrase*/pharmacology
Humans ; Prevalence ; Drug Resistance, Viral/genetics ; Mutation ; Genotype ; China/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antiviral Activity of Probenecid and Oseltamivir on Influenza Virus Replication.
Autorzy:
Murray J; Department of Infectious Disease, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Martin DE; TrippBio, Inc., Jacksonville, FL 32256, USA.
Sancilio FD; TrippBio, Inc., Jacksonville, FL 32256, USA.
Tripp RA; Department of Infectious Disease, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.; TrippBio, Inc., Jacksonville, FL 32256, USA.
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Źródło:
Viruses [Viruses] 2023 Nov 30; Vol. 15 (12). Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Influenza, Human*
Influenza Vaccines*/therapeutic use
Humans ; Animals ; Mice ; Oseltamivir/pharmacology ; Oseltamivir/therapeutic use ; Probenecid/pharmacology ; Probenecid/therapeutic use ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Enzyme Inhibitors/pharmacology ; Virus Replication ; Neuraminidase ; Drug Resistance, Viral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam.
Autorzy:
Bwire GM; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium. .; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania. .
Aiko BG; Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Mosha IH; Department of Behavioural Sciences, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65015, Tanzania.
Kilapilo MS; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.
Mangara A; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Dar es Salaam Urban Cohort Study, Dar es Salaam, 65013, Tanzania.
Kazonda P; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Dar es Salaam Urban Cohort Study, Dar es Salaam, 65013, Tanzania.
Swai JP; Department of Business Studies, School of Business, Mzumbe University, Dar es Salaam, 20266, Tanzania.
Swalehe O; Department of Business Studies, School of Business, Mzumbe University, Dar es Salaam, 20266, Tanzania.
Jordan MR; Tufts University School of Medicine, Boston, MA, USA.
Vercauteren J; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium.
Sando D; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Temba D; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Shao A; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Mauka W; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Decouttere C; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Vandaele N; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Sangeda RZ; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.
Killewo J; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65015, Tanzania.
Vandamme AM; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium.; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 22; Vol. 13 (1), pp. 20493. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV-1*/genetics
HIV Seropositivity*/drug therapy
Humans ; Adult ; Male ; Female ; Child ; Tanzania ; Cross-Sectional Studies ; Drug Resistance, Viral/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Mutation ; Integrases/genetics ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Web Service for HIV Drug Resistance Prediction Based on Analysis of Amino Acid Substitutions in Main Drug Targets.
Autorzy:
Paremskaia AI; Department of Bioinformatics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.; Live Sciences Research Center, Moscow Institute of Physics and Technology, National Research University, Institutsky Lane 9, Dolgoprudny 141700, Russia.
Rudik AV; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Filimonov DA; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Lagunin AA; Department of Bioinformatics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Poroikov VV; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Tarasova OA; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
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Źródło:
Viruses [Viruses] 2023 Nov 11; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Humans ; Bayes Theorem ; Amino Acid Substitution ; Reproducibility of Results ; HIV Reverse Transcriptase/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Drug Resistance, Viral/genetics ; HIV Protease/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study.
Autorzy:
Torii Y; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Horiba K; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.; Department of Genetics, Research Institute of Environmental Medicine Nagoya University, Furo-cho, Chikusa-ku, 464-8601, Nagoya, Japan.; Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Kawada JI; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Haruta K; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Yamaguchi M; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Suzuki T; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Uryu H; Department of Pediatrics, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, Japan.
Kashiwa N; Department of Pediatrics, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, Japan.
Goishi K; Department of Pediatrics, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, Japan.
Ogi T; Department of Genetics, Research Institute of Environmental Medicine Nagoya University, Furo-cho, Chikusa-ku, 464-8601, Nagoya, Japan.; Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan.
Ito Y; Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, 466-8550, Nagoya, Japan. .; Department of Pediatrics and Child Health, Nihon University School of Medicine, 30-1 Oyaguchi, Kami-cho, Itabashi-ku, 173-8610, Tokyo, Japan. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2022 Jun 22; Vol. 22 (1), pp. 568. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Antiviral Agents*/therapeutic use
Cytomegalovirus Infections*/congenital
Cytomegalovirus Infections*/drug therapy
Drug Resistance, Viral*/genetics
Child ; Ganciclovir/therapeutic use ; Humans ; Mutation ; Retrospective Studies ; Valganciclovir/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies.
Autorzy:
Singh AK; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Das K; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
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Źródło:
Viruses [Viruses] 2022 May 11; Vol. 14 (5). Date of Electronic Publication: 2022 May 11.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Viral*
HIV Infections*
HIV-1*/drug effects
Reverse Transcriptase Inhibitors*/pharmacology
Reverse Transcriptase Inhibitors*/therapeutic use
HIV Reverse Transcriptase/genetics ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents.
Autorzy:
Krasnov VP; Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg 620108, Russia.
Andronova VL; Gamaleya National Research Center for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia.
Belyavsky AV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.
Borisevich SS; Ufa Institute of Chemistry, Russian Academy of Sciences, Ufa 450078, Russia.
Galegov GA; Gamaleya National Research Center for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow 123098, Russia.
Kandarakov OF; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.
Gruzdev DA; Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg 620108, Russia.
Vozdvizhenskaya OA; Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg 620108, Russia.
Levit GL; Postovsky Institute of Organic Synthesis, Russian Academy of Sciences (Ural Branch), Ekaterinburg 620108, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 31; Vol. 28 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Herpes Simplex*/drug therapy
Herpesvirus 1, Human*
Humans ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Acyclovir/pharmacology ; DNA-Directed DNA Polymerase/genetics ; Drug Resistance, Viral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trends in HIV-1 pretreatment drug resistance and HIV-1 variant dynamics among antiretroviral therapy-naive Ethiopians from 2003 to 2018: a pooled sequence analysis.
Autorzy:
Kiros M; Department of Medical Laboratory Science, CollegeofMedicineandHealth Sciences, Aksum University, Aksum, Ethiopia. .
Biset S; Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Gebremariam B; Department of Medical Laboratory Science, CollegeofMedicineandHealth Sciences, Aksum University, Aksum, Ethiopia.
Yalew GT; Department of Medical Laboratory Science, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.
Abegaz WE; Department of Microbiology, Parasitology, and Immunology, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Geteneh A; Department of Medical Laboratory Sciences, College of Health Sciences, Woldia University, Woldia, Ethiopia.
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Źródło:
Virology journal [Virol J] 2023 Oct 25; Vol. 20 (1), pp. 243. Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
HIV-1*/genetics
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV Seropositivity*/drug therapy
Humans ; Reverse Transcriptase Inhibitors/therapeutic use ; Mutation ; Genotype ; Drug Resistance, Viral/genetics ; Prevalence ; Sequence Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study.
Autorzy:
Togna Pabo WLR; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.; Faculty of Science, University of Buea, Buea, Cameroon.
Fokam J; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.; Faculty of Health Sciences, University of Buea, Buea, Cameroon.; National HIV Drug Resistance Group, Ministry of Public Health, Yaoundé, Cameroon.
Njume D; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.; Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Takou D; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Santoro MM; University of Rome Tor Vergata, Rome, Italy.
Nyasa RB; Faculty of Science, University of Buea, Buea, Cameroon.
Chenwi C; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Mpouel ML; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Beloumou G; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Jagni ESN; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; University of Rome Tor Vergata, Rome, Italy.; Evangelic University of Cameroon, Bandjoun, Cameroon.
Nka AD; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; University of Rome Tor Vergata, Rome, Italy.; Evangelic University of Cameroon, Bandjoun, Cameroon.
Ka'e AC; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; University of Rome Tor Vergata, Rome, Italy.
Teto G; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Dambaya B; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Djupsa S; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Gouissi Anguechia DH; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Evariste M; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.
Kamta C; Mfou District Hospital, Mfou, Cameroon.
Bala L; Mbalmayo District Hospital, Mbalmayo, Cameroon.
Lambo V; Nkomo Integrated Health Center, Nkomo, Cameroon.
Halle-Ekane EG; Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Colizzi V; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; University of Rome Tor Vergata, Rome, Italy.; Evangelic University of Cameroon, Bandjoun, Cameroon.
Perno CF; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; University of Rome Tor Vergata, Rome, Italy.; Bambino Gesu Pediatric Hospital, Rome, Italy.
Ndjolo A; Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaoundé, Cameroon.; Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Ndip Ndip R; Faculty of Science, University of Buea, Buea, Cameroon.
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Źródło:
PloS one [PLoS One] 2023 Oct 25; Vol. 18 (10), pp. e0293326. Date of Electronic Publication: 2023 Oct 25 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
HIV Infections*/drug therapy
HIV Seropositivity*/drug therapy
Humans ; Male ; Female ; Adolescent ; Cohort Studies ; Cameroon/epidemiology ; Drug Resistance, Viral/genetics ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 drug resistance and genetic transmission network among newly diagnosed people living with HIV/AIDS in Ningbo, China between 2018 and 2021.
Autorzy:
Hong H; School of Public health, Health Science Center, Ningbo University, Ningbo, Zhengjiang, 315211, China.
Tang C; School of Public health, Health Science Center, Ningbo University, Ningbo, Zhengjiang, 315211, China.
Liu Y; Ningbo Center for Disease Control and Prevention, Ningbo, Zhengjiang, 315010, China.
Jiang H; Ningbo Center for Disease Control and Prevention, Ningbo, Zhengjiang, 315010, China.
Fang T; School of Public health, Health Science Center, Ningbo University, Ningbo, Zhengjiang, 315211, China.
Xu G; School of Public health, Health Science Center, Ningbo University, Ningbo, Zhengjiang, 315211, China. .
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Źródło:
Virology journal [Virol J] 2023 Oct 13; Vol. 20 (1), pp. 233. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acquired Immunodeficiency Syndrome*
HIV-1*/genetics
HIV Infections*/epidemiology
HIV Seropositivity*
Humans ; Middle Aged ; Cross-Sectional Studies ; Phylogeny ; Genotype ; China/epidemiology ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV Drug Resistance Patterns and Characteristics Associated with Clinically Significant Drug Resistance among Children with Virologic Failure on Antiretroviral Treatment in Kenya: Findings from the Opt4Kids Randomized Controlled Trial.
Autorzy:
Abuogi L; Department of Pediatrics, University of Colorado, Denver, CO 80045, USA.
Oyaro P; Health Innovations Kenya (HIK), Kisumu 40100, Kenya.; United States Agency for International Development, Washington, DC 20004, USA.
Wakjira G; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Thomas KK; Department of Global Health, University of Washington, Seattle, WA 98105, USA.
Scallon AJ; Department of Global Health, University of Washington, Seattle, WA 98105, USA.
Mukui I; Drugs for Neglected Diseases Initiative (DNDI), Nairobi 21936, Kenya.
Chohan BH; Department of Global Health, University of Washington, Seattle, WA 98105, USA.; Kenya Medical Research Institute, Nairobi 00200, Kenya.
Brown E; UWKenya, Nairobi 00200, Kenya.
Karauki E; UWKenya, Nairobi 00200, Kenya.
Yongo N; UWKenya, Nairobi 00200, Kenya.
Ahmed B; Department of Pediatrics, University of Colorado, Denver, CO 80045, USA.
Hassan SA; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Wagude J; Department of Health, Ministry of Health, Siaya 40600, Kenya.
Kinywa E; Department of Health, Ministry of Health, Kisumu 40100, Kenya.
Otieno L; Family AIDS Care and Education Services, Kenya Medical Research Institute, Kisumu 40100, Kenya.
Kingwara L; National HIV Reference Laboratory, Kenya Ministry of Health, Nairobi 00202, Kenya.
Oyaro B; Kenya Medical Research Institute-CDC, Kisumu 40100, Kenya.
Frenkel LM; Department of Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Global Health, University of Washington, Seattle, WA 98105, USA.; Departments of Pediatrics, University of Washington, Seattle, WA 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 98195, USA.
John-Stewart G; Department of Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Global Health, University of Washington, Seattle, WA 98105, USA.; Departments of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Patel RC; Department of Medicine, University of Washington, Seattle, WA 98195, USA.; Department of Global Health, University of Washington, Seattle, WA 98105, USA.
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Źródło:
Viruses [Viruses] 2023 Oct 12; Vol. 15 (10). Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV Infections*/drug therapy
HIV-1*/genetics
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
Humans ; Child ; Female ; Male ; Kenya ; Treatment Failure ; Drug Resistance, Viral/genetics ; Anti-Retroviral Agents/therapeutic use ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transmitted drug resistance and subtype patterns of viruses from reported new HIV diagnoses in Germany, 2017-2020.
Autorzy:
Fiebig U; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Altmann B; Unit 18 'HIV and other Retroviruses', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Hauser A; Unit 18 'HIV and other Retroviruses', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Koppe U; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Hanke K; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Gunsenheimer-Bartmeyer B; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Bremer V; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Baumgarten A; Center for Infectiology Berlin-Prenzlauer Berg, Nordufer 20, 13353, Berlin, Germany.
Bannert N; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 Oct 10; Vol. 23 (1), pp. 673. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/diagnosis
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Sexual and Gender Minorities*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Viruses*
Male ; Humans ; Homosexuality, Male ; Drug Resistance, Viral/genetics ; Mutation ; DNA-Directed RNA Polymerases/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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