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Wyszukujesz frazę ""Drug Tolerance"" wg kryterium: Temat


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Tytuł :
Deubiquitinating enzyme inhibitor alleviates cyclin A1-mediated proteasome inhibitor tolerance in mixed-lineage leukemia.
Autorzy :
Ge M; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xu Q; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kang T; Department of Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li D; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang R; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen Z; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xie S; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang W; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu H; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Jun; Vol. 112 (6), pp. 2287-2298. Date of Electronic Publication: 2021 Apr 05.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*/genetics
Cyclin A1/*metabolism
Deubiquitinating Enzymes/*antagonists & inhibitors
Leukemia, Biphenotypic, Acute/*drug therapy
Proteasome Inhibitors/*pharmacology
Cell Cycle Checkpoints/drug effects ; Cell Cycle Checkpoints/genetics ; Cell Line, Tumor ; Chromatin/metabolism ; Cyclin A1/genetics ; Drug Resistance, Neoplasm ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Humans ; Leukemia, Biphenotypic, Acute/genetics ; Leukemia, Biphenotypic, Acute/metabolism ; Leukemia, Biphenotypic, Acute/pathology ; Methylation ; Myeloid-Lymphoid Leukemia Protein/genetics ; Myeloid-Lymphoid Leukemia Protein/metabolism ; Prognosis ; Proteasome Inhibitors/therapeutic use ; Ubiquitination
Czasopismo naukowe
Tytuł :
Safety and tolerability of fixed-dose combinations of ibuprofen and acetaminophen: pooled analysis of phase 1-3 clinical trials.
Autorzy :
Su J; Pfizer Consumer Healthcare, Pfizer Inc., Collegeville, PA, USA.
Leyva R; Pfizer Consumer Healthcare, Pfizer Inc., Madison, NJ, USA.
Kellstein D; Pfizer Consumer Healthcare, Pfizer Inc., Madison, NJ, USA.
Cruz-Rivera M; Pfizer Consumer Healthcare, Pfizer Inc., Madison, NJ, USA.
Meeves S; Pfizer Consumer Healthcare, Pfizer Inc., Madison, NJ, USA.
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Źródło :
Postgraduate medicine [Postgrad Med] 2021 Jun; Vol. 133 (5), pp. 565-571. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Acetaminophen/*administration & dosage
Clinical Trials, Phase I as Topic/*methods
Clinical Trials, Phase II as Topic/*methods
Clinical Trials, Phase III as Topic/*methods
Ibuprofen/*administration & dosage
Randomized Controlled Trials as Topic/*methods
Adult ; Analgesics, Non-Narcotic/administration & dosage ; Anti-Inflammatory Agents, Non-Steroidal ; Disorders of Excessive Somnolence ; Drug Therapy, Combination ; Female ; Humans ; Male ; Young Adult
Czasopismo naukowe
Tytuł :
Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia.
Autorzy :
Muchhala KH; Department of Pharmacology and Toxicology, Virginia Commonwealth University, 1112 East Clay St, Richmond, VA, 23298, USA.
Jacob JC; Department of Pharmacology and Toxicology, Virginia Commonwealth University, 1112 East Clay St, Richmond, VA, 23298, USA.
Dewey WL; Department of Pharmacology and Toxicology, Virginia Commonwealth University, 1112 East Clay St, Richmond, VA, 23298, USA.
Akbarali HI; Department of Pharmacology and Toxicology, Virginia Commonwealth University, 1112 East Clay St, Richmond, VA, 23298, USA. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 May 15; Vol. 899, pp. 174007. Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*pharmacology
Ganglia, Spinal/*drug effects
Morphine/*pharmacology
Neurons/*drug effects
Nociceptive Pain/*prevention & control
Receptors, Opioid, mu/*agonists
Spiro Compounds/*pharmacology
Thiophenes/*pharmacology
beta-Arrestin 2/*metabolism
Animals ; Behavior, Animal/drug effects ; Cells, Cultured ; Disease Models, Animal ; Female ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/physiopathology ; Male ; Mice, Knockout ; Neurons/metabolism ; Nociceptive Pain/genetics ; Nociceptive Pain/metabolism ; Nociceptive Pain/physiopathology ; Pain Threshold/drug effects ; Receptors, Opioid, mu/metabolism ; Time Factors ; beta-Arrestin 2/deficiency ; beta-Arrestin 2/genetics
Czasopismo naukowe
Tytuł :
Repression of transcription factor AtWRKY47 confers tolerance to boron toxicity in Arabidopsis thaliana.
Autorzy :
Feng Y; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Cui R; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Huang Y; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Shi L; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Wang S; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Xu F; National Key Laboratory of Crop Genetic Improvement, and Microelement Research Centre, Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Sep 01; Vol. 220, pp. 112406. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*/genetics
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
Boron/*metabolism
Transcription Factors/*metabolism
Arabidopsis/drug effects ; Arabidopsis/genetics ; Arabidopsis/growth & development ; Arabidopsis Proteins/genetics ; Boron/toxicity ; Gene Expression Regulation, Plant ; Mutation ; Phenotype ; Plants, Genetically Modified/drug effects ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
A miniature pig model of pharmacological tolerance to long-term sedation with the intravenous benzodiazepines; midazolam and remimazolam.
Autorzy :
Io T; Research Department, Ono Pharmaceutical Co., Ltd, Mishima, Osaka, 618-8585, Japan.
Saunders R; Biomed Contextm, Bergisch Gladbach, Germany.
Pesic M; Paion GmbH, Martinstr. 2-10, 52062, Aachen, Germany.
Petersen KU; RWTH Aachen, Germany.
Stoehr T; Paion GmbH, Martinstr. 2-10, 52062, Aachen, Germany. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Apr 05; Vol. 896, pp. 173886. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Drug Tolerance*
Benzodiazepines/*administration & dosage
Consciousness/*drug effects
Hypnotics and Sedatives/*administration & dosage
Midazolam/*administration & dosage
Administration, Intravenous ; Animals ; Dose-Response Relationship, Drug ; Male ; Models, Animal ; Recovery of Function ; Swine ; Swine, Miniature ; Time Factors
Czasopismo naukowe
Tytuł :
Involvement of TCF7L2 in generation of morphine-induced antinociceptive tolerance and hyperalgesia by modulating TLR4/ NF-κB/NLRP3 in microglia.
Autorzy :
Chen J; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150081, China.
Wang G; Harbin Medical University Sino-Russian Research Center Pain Management Research Institute, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province 150001, China. Electronic address: .
Sun T; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150081, China.
Ma C; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150081, China.
Huo X; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150081, China.
Kong Y; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150081, China.
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Apr 01; Vol. 416, pp. 115458. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*toxicity
Hyperalgesia/*chemically induced
Microglia/*drug effects
Morphine/*toxicity
NF-kappa B/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Nociceptive Pain/*prevention & control
Toll-Like Receptor 4/*metabolism
Transcription Factor 7-Like 2 Protein/*metabolism
Animals ; Cell Line ; Disease Models, Animal ; Hyperalgesia/metabolism ; Hyperalgesia/physiopathology ; Male ; Mice ; Microglia/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Nociceptive Pain/metabolism ; Nociceptive Pain/physiopathology ; Pain Threshold/drug effects ; Signal Transduction ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Spinal Cord/physiopathology ; Toll-Like Receptor 4/genetics ; Transcription Factor 7-Like 2 Protein/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Haloperidol potentiates antinociceptive effects of morphine and disrupt opioid tolerance.
Autorzy :
Mena-Valdés LC; Laboratorio No.7 'Dolor y Analgesia' Del Departamento de Farmacobiología, Cinvestav-Sede Sur, Calz. de Los Tenorios No. 235, Col. Granjas Coapa, C.P. 14330, Ciudad de México, Mexico. Electronic address: .
Blanco-Hernández Y; Laboratorio No.7 'Dolor y Analgesia' Del Departamento de Farmacobiología, Cinvestav-Sede Sur, Calz. de Los Tenorios No. 235, Col. Granjas Coapa, C.P. 14330, Ciudad de México, Mexico. Electronic address: .
Espinosa-Juárez JV; Escuela de Ciencias Químicas Sede Ocozocoautla, Universidad Autónoma de Chiapas, Ocozocoautla de Espinosa, Chiapas, Mexico. Electronic address: .
López-Muñoz FJ; Laboratorio No.7 'Dolor y Analgesia' Del Departamento de Farmacobiología, Cinvestav-Sede Sur, Calz. de Los Tenorios No. 235, Col. Granjas Coapa, C.P. 14330, Ciudad de México, Mexico. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Feb 15; Vol. 893, pp. 173825. Date of Electronic Publication: 2020 Dec 19.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*pharmacology
Haloperidol/*pharmacology
Morphine/*pharmacology
Neuralgia/*drug therapy
Nociception/*drug effects
Receptors, sigma/*antagonists & inhibitors
Analgesics, Opioid/toxicity ; Animals ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Drug Synergism ; Drug Therapy, Combination ; Male ; Morphine/toxicity ; Neuralgia/metabolism ; Neuralgia/physiopathology ; Rats, Wistar ; Receptors, sigma/metabolism ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
Tolerability of Highly Protein Bound Targeted Oral Oncolytic Drugs in Patients With Hypoalbuminemia: A Retrospective Analysis.
Autorzy :
Murdock JL; Butler University, Indianapolis, IN, USA.
Duco MR; Butler University, Indianapolis, IN, USA.
Reeves DJ; Butler University, Indianapolis, IN, USA.; Franciscan Health Indianapolis, Indianapolis, IN, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Feb; Vol. 55 (2), pp. 165-173. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Antineoplastic Agents/*metabolism
Hypoalbuminemia/*drug therapy
Serum Albumin/*metabolism
Administration, Oral ; Adult ; Aged ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Female ; Humans ; Hypoalbuminemia/blood ; Incidence ; Male ; Middle Aged ; Proportional Hazards Models ; Protein Binding ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Effect of captopril, an angiotensin-converting enzyme inhibitor, on morphine analgesia and tolerance in rats, and elucidating the inflammation and endoplasmic reticulum stress pathway in this effect.
Autorzy :
Taskiran AS; Department of Physiology, Sivas Cumhuriyet University School of Medicine, Sivas, Turkey. Electronic address: .
Avci O; Department of Anesthesiology and Reanimation, Sivas Cumhuriyet University, School of Medicine, Sivas, Turkey.
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Jan 10; Vol. 741, pp. 135504. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*administration & dosage
Angiotensin-Converting Enzyme Inhibitors/*administration & dosage
Captopril/*administration & dosage
Endoplasmic Reticulum Stress/*drug effects
Ganglia, Spinal/*drug effects
Morphine/*administration & dosage
Animals ; Ganglia, Spinal/metabolism ; Inflammation/metabolism ; Inflammation/prevention & control ; Inflammation Mediators/metabolism ; Male ; Nociception/drug effects ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The citrus flavanone naringenin prevents the development of morphine analgesic tolerance and conditioned place preference in male rats.
Autorzy :
Alifarsangi A; Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.; Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
Esmaeili-Mahani S; Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.; Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
Sheibani V; Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Abbasnejad M; Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
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Źródło :
The American journal of drug and alcohol abuse [Am J Drug Alcohol Abuse] 2021 Jan 02; Vol. 47 (1), pp. 43-51. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*administration & dosage
Flavanones/*administration & dosage
Morphine/*administration & dosage
Analgesics, Opioid/adverse effects ; Animals ; Citrus ; Flavanones/therapeutic use ; Male ; Morphine/adverse effects ; Rats ; Rats, Wistar ; Spinal Cord/drug effects
Czasopismo naukowe
Tytuł :
Low-dose cannabinoid receptor 2 agonist induces microglial activation in a cancer pain-morphine tolerance rat model.
Autorzy :
Ma C; Department of Anesthesiology, The Fourth Hospital of Harbin Medical University, Harbin, China.
Zhang M; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Liu L; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Zhang P; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Liu D; Department of Anesthesiology, The Fourth Hospital of Harbin Medical University, Harbin, China.
Zheng X; Department of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin, China.
Zhong X; Department of Anesthesiology, The Fourth Hospital of Harbin Medical University, Harbin, China.
Wang G; Department of Anesthesiology, The Fourth Hospital of Harbin Medical University, Harbin, China; Pain Research Institute of Heilongjiang Academy of Medical Sciences, Harbin, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118635. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Cancer Pain/*drug therapy
Morphine/*pharmacology
Pain Threshold/*drug effects
Receptor, Cannabinoid, CB2/*agonists
Animals ; Cancer Pain/metabolism ; Cannabinoids/pharmacology ; Catheterization ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Hyperalgesia/physiopathology ; Immune System ; Interleukin-1beta/metabolism ; Male ; Rats ; Rats, Wistar ; Signal Transduction ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
Nicotine chronic tolerance development and withdrawal in the planaria (Schmidtea mediterranea).
Autorzy :
Sal F; Department of Neuroscience, Psychology & Behaviour, University of Leicester, UK.
Prados J; Department of Neuroscience, Psychology & Behaviour, University of Leicester, UK.
Urcelay GP; Department of Neuroscience, Psychology & Behaviour, University of Leicester, UK. Electronic address: .
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Źródło :
Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2021 Jan; Vol. 200, pp. 173075. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Tolerance*
Locomotion/*drug effects
Nicotine/*pharmacology
Planarians/*drug effects
Substance Withdrawal Syndrome/*metabolism
Animals ; Behavior, Addictive/metabolism ; Behavior, Animal/drug effects ; Dose-Response Relationship, Drug ; Humans ; Mecamylamine/pharmacology ; Nicotinic Agonists/pharmacology ; Nicotinic Antagonists/pharmacology ; Receptors, Nicotinic/metabolism
Czasopismo naukowe
Tytuł :
Romiplostim is effective for eltrombopag-refractory aplastic anemia: results of a retrospective study.
Autorzy :
Ise M; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
Iizuka H; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
Kamoda Y; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
Hirao M; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
Kida M; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
Usuki K; Department of Hematology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, Shinagawa-ku, Tokyo, 141-8625, Japan. .
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Źródło :
International journal of hematology [Int J Hematol] 2020 Dec; Vol. 112 (6), pp. 787-794. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article
MeSH Terms :
Benzoates*
Drug Tolerance*
Hydrazines*
Pyrazoles*
Anemia, Aplastic/*drug therapy
Anemia, Refractory/*drug therapy
Receptors, Fc/*administration & dosage
Recombinant Fusion Proteins/*administration & dosage
Thrombopoietin/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Anemia, Aplastic/blood ; Drug Substitution ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Platelet Count ; Prospective Studies ; Receptors, Thrombopoietin/agonists ; Recombinant Fusion Proteins/pharmacology ; Retrospective Studies ; Thrombopoietin/pharmacology
Czasopismo naukowe
Tytuł :
Efficacy of anakinra for idiopathic and non-idiopathic pericarditis refractory or intolerant to conventional therapy.
Autorzy :
Shaukat MH; Department of Medicine, Albany Medical College, USA.
Singh S; Department of Medicine, Albany Medical College, USA.
Davis K; Albany Medical College, USA.
Torosoff M; Department of Cardiology, Albany Medical College, USA.
Peredo-Wende R; Department of Rheumatology, Albany Medical College, USA.
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Źródło :
European heart journal. Acute cardiovascular care [Eur Heart J Acute Cardiovasc Care] 2020 Dec; Vol. 9 (8), pp. 888-892. Date of Electronic Publication: 2020 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Interleukin 1 Receptor Antagonist Protein/*therapeutic use
Pericarditis/*drug therapy
Antirheumatic Agents/therapeutic use ; Female ; Follow-Up Studies ; Humans ; Inpatients ; Male ; Middle Aged ; Recurrence ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
PREDICTIVE FACTORS FOR LOSS OF RESPONSE TO ANTI-TNF IN CROHN'S DISEASE.
Autorzy :
Santos BRMD; Department of Surgery, Regional Hospital Rosa Pedrossian, Campo Grande, MS, Brazil.
Santos CHMD; Department of Surgery, Regional Hospital Rosa Pedrossian, Campo Grande, MS, Brazil.; Medicine, Anhanguera-Uniderp University, Campo Grande, MS, Brazil.
Santos VRMD; Department of Surgery, Regional Hospital Rosa Pedrossian, Campo Grande, MS, Brazil.
Torrez CYG; Department of Surgery, Regional Hospital Rosa Pedrossian, Campo Grande, MS, Brazil.
Palomares-Junior D; Department of Surgery, Regional Hospital Rosa Pedrossian, Campo Grande, MS, Brazil.
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Źródło :
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2020 Nov 20; Vol. 33 (2), pp. e1522. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Crohn Disease/*drug therapy
Tumor Necrosis Factor Inhibitors/*therapeutic use
Adolescent ; Adult ; Crohn Disease/surgery ; Female ; Humans ; Infliximab/therapeutic use ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Tumor Necrosis Factor-alpha ; Young Adult
Czasopismo naukowe
Tytuł :
Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution.
Autorzy :
Pereira R; Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Gothenburg, Sweden.; The Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, 41296 Gothenburg, Sweden.
Mohamed ET; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark.
Radi MS; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark.
Herrgård MJ; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark.; BioInnovation Institute, 2200 Copenhagen N, Denmark.
Feist AM; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark.; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093.
Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Gothenburg, Sweden.; The Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, 41296 Gothenburg, Sweden.; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet, 2800 Kongens Lyngby, Denmark.; BioInnovation Institute, 2200 Copenhagen N, Denmark.
Chen Y; Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Gothenburg, Sweden; .; The Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, 41296 Gothenburg, Sweden.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 10; Vol. 117 (45), pp. 27954-27961. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coumaric Acids/*metabolism
Drug Tolerance/*genetics
Acids/metabolism ; Adaptation, Physiological/genetics ; Amino Acids, Aromatic/metabolism ; Amino Acids, Aromatic/toxicity ; Coumaric Acids/toxicity ; Directed Molecular Evolution ; Drug Tolerance/physiology ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Transcription Factors/metabolism ; Whole Genome Sequencing/methods
Czasopismo naukowe
Tytuł :
Systems evaluation reveals novel transporter YohJK renders 3-hydroxypropionate tolerance in Escherichia coli.
Autorzy :
Nguyen-Vo TP; School of Energy and Chemical Engineering, UNIST, Ulsan, 44919, Republic of Korea.; School of Chemical and Biomolecular Engineering, Pusan National University, Busan, 46241, Republic of Korea.
Ko S; School of Energy and Chemical Engineering, UNIST, Ulsan, 44919, Republic of Korea.
Ryu H; School of Energy and Chemical Engineering, UNIST, Ulsan, 44919, Republic of Korea.
Kim JR; School of Chemical and Biomolecular Engineering, Pusan National University, Busan, 46241, Republic of Korea.
Kim D; School of Energy and Chemical Engineering, UNIST, Ulsan, 44919, Republic of Korea. .
Park S; School of Energy and Chemical Engineering, UNIST, Ulsan, 44919, Republic of Korea. .; School of Chemical and Biomolecular Engineering, Pusan National University, Busan, 46241, Republic of Korea. .
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Źródło :
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 19064. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Tolerance*
Escherichia coli/*drug effects
Escherichia coli/*genetics
Escherichia coli Proteins/*genetics
Lactic Acid/*analogs & derivatives
Binding Sites ; Chromatin Immunoprecipitation Sequencing ; Escherichia coli Proteins/metabolism ; Gene Deletion ; Gene Expression Regulation, Bacterial ; Gene Regulatory Networks ; Lactic Acid/pharmacology ; Operon ; Protein Binding
Czasopismo naukowe
Tytuł :
Impact of Patient and Model of Care Factors on Titration and Tolerability of Sacubitril/Valsartan: An Early Australian Real-World Experience.
Autorzy :
Dashwood A; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia; University of Queensland, Brisbane, Qld, Australia; Cardio-Vascular Molecular & Therapeutics Translational Research Group, Brisbane, Qld, Australia; Griffith University, Southport, Qld, Australia. Electronic address: .
Vale C; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia.
Laher S; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia.
Chui F; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia.
Rheault H; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia; School of Nursing, Queensland University of Technology (QUT), Brisbane, Qld, Australia.
Gan J; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia.
Wong YW; Queensland Advanced Heart Failure and Cardiac Transplantation Unit, Heart Lung Institute, The Prince Charles Hospital, Brisbane, Qld, Australia; University of Queensland, Brisbane, Qld, Australia; Cardio-Vascular Molecular & Therapeutics Translational Research Group, Brisbane, Qld, Australia.
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Źródło :
Heart, lung & circulation [Heart Lung Circ] 2020 Nov; Vol. 29 (11), pp. 1688-1695. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Aminobutyrates/*therapeutic use
Heart Failure/*drug therapy
Stroke Volume/*physiology
Tetrazoles/*therapeutic use
Angiotensin Receptor Antagonists/therapeutic use ; Australia/epidemiology ; Drug Combinations ; Female ; Follow-Up Studies ; Heart Failure/epidemiology ; Heart Failure/physiopathology ; Humans ; Male ; Middle Aged ; Morbidity/trends ; Neprilysin ; Prognosis ; Retrospective Studies ; Survival Rate/trends ; Time Factors
Czasopismo naukowe
Tytuł :
Antibiotic tolerance.
Autorzy :
Westblade LF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, United States of America.; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, United States of America.
Errington J; The Centre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Dörr T; Weill Institute for Cell and Molecular Biology and Department of Microbiology, Cornell University, Ithaca, New York, United States of America.; Department of Microbiology, Cornell University, Ithaca, New York, United States of America.; Cornell Institute of Host-Pathogen Interactions and Disease, Cornell University, Ithaca, New York, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Oct 15; Vol. 16 (10), pp. e1008892. Date of Electronic Publication: 2020 Oct 15 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Bacterial*
Drug Tolerance*
Evolution, Molecular*
Anti-Bacterial Agents/*pharmacology
Humans
Czasopismo naukowe
Tytuł :
Pharmacological Chaperones Attenuate the Development of Opioid Tolerance.
Autorzy :
Okuyama Y; Sanmu Medical Center, Department of Anesthesiology, 167 Naruto, Sanmu City 289-1326, Japan.
Jin H; Department of Anesthesiology, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City 260-8670, Japan.
Kokubun H; Department of Anesthesiology, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City 260-8670, Japan.
Aoe T; Pain Center, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara City 299-0111, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 13; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Tolerance*
Analgesics, Opioid/*pharmacology
Morphine/*pharmacology
Nociception/*drug effects
Phenylbutyrates/*pharmacology
Taurochenodeoxycholic Acid/*pharmacology
Animals ; Endoplasmic Reticulum Stress ; Glycogen Synthase Kinase 3 beta/metabolism ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe

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