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You search for a phrase ""Drug Tolerance"" according to the criterion: Subject Terms

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Title:
Experimental Study: Interleukin-31 Augments Morphine-Induced Antinociceptive Activity and Suppress Tolerance Development in Mice.
Authors:
Arai I; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Tsuji M; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.
Saito S; Division of Environmental Allergy, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Tokyo 105-8461, Japan.
Takeda H; Department of Pharmacology, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8510, Japan.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 20; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 20.
Publication Type:
Journal Article
MeSH Terms:
Analgesics*/pharmacology
Analgesics*/therapeutic use
Drug Tolerance*
Morphine*/pharmacology
Morphine*/therapeutic use
Animals ; Mice ; Analgesics, Opioid/pharmacology ; Dose-Response Relationship, Drug ; Interleukins/genetics ; Pruritus/drug therapy
Academic Journal
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Title:
Development of opioid analgesic tolerance in rat to extended-release buprenorphine formulated for laboratory subjects.
Authors:
Larson CM; Comparative and Molecular Biosciences, University of Minnesota College of Veterinary Medicine, St Paul, MN, United States of America.
Barajas C; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN, United States of America.
Kitto KF; Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN, United States of America.
Wilcox GL; Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN, United States of America.; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, United States of America.; Department of Dermatology, University of Minnesota Medical School, Minneapolis, MN, United States of America.
Fairbanks CA; Comparative and Molecular Biosciences, University of Minnesota College of Veterinary Medicine, St Paul, MN, United States of America.; Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN, United States of America.; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN, United States of America.; Department of Pharmaceutics, University of Minnesota College of Pharmacy, Minneapolis, MN, United States of America.
Peterson CD; Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN, United States of America.; Department of Neuroscience, University of Minnesota Medical School, Minneapolis, MN, United States of America.; Department of Pharmaceutics, University of Minnesota College of Pharmacy, Minneapolis, MN, United States of America.
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Source:
PloS one [PLoS One] 2024 Mar 21; Vol. 19 (3), pp. e0298819. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Analgesics, Opioid*/therapeutic use
Buprenorphine*
Humans ; Female ; Rats ; Male ; Animals ; Drug Tolerance ; Analgesics/therapeutic use ; Pain/drug therapy
Academic Journal
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Title:
The Tumor Suppressor SOCS1 Diminishes Tolerance to Oxidative Stress in Hepatocellular Carcinoma.
Authors:
Shukla, Akhil (AUTHOR)
Khan, Md Gulam Musawwir (AUTHOR)
Cayarga, Anny Armas (AUTHOR)
Namvarpour, Mozhdeh (AUTHOR)
Chowdhury, Mohammad Mobarak H. (AUTHOR)
Levesque, Dominique (AUTHOR)
Lucier, Jean-François (AUTHOR)
Boisvert, François-Michel (AUTHOR)
Ramanathan, Sheela (AUTHOR)
Ilangumaran, Subburaj (AUTHOR)
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Source:
Cancers. Jan2024, Vol. 16 Issue 2, p292. 24p.
Academic Journal
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Title:
Efficacy and safety of adamgammadex for reversing rocuronium-induced deep neuromuscular blockade: A multicenter, randomized, phase IIb study.
Authors:
Zhao Y; Department of Anesthesiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen S; Department of Anesthesiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xie W; Department of Anesthesiology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.
Zhang X; Department of Anesthesiology, Tongji Hospital of Tongji University, Shanghai, China.
Chen G; Department of Anesthesiology, The 900 Hospital of the Chinese People's Liberation Army Joint Logistic Support Force, Fuzhou, China.
Ji F; Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wang D; Department of Anesthesiology, Peking University First Hosptial, Beijing, China.
Qi Y; Hangzhou Adamerck Pharmlabs Inc, Hangzhou, China.
Jie Q; Hangzhou Adamerck Pharmlabs Inc, Hangzhou, China.
Su D; Department of Anesthesiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu W; Department of Anesthesiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Source:
Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13691.
Publication Type:
Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Journal Article
MeSH Terms:
Neuromuscular Blockade*/adverse effects
Humans ; Rocuronium/adverse effects ; Sugammadex/adverse effects ; Drug Tolerance ; Immune Tolerance
Academic Journal
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Title:
β -Elemene Improves Morphine Tolerance in Bone Cancer Pain via N-Methyl-D-Aspartate Receptor 2B Subunit-Mediated μ -Opioid Receptor.
Authors:
Zhou Q; Department of Rare and Head and Neck Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Gong L; Department of Rare and Head and Neck Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Bao G; Rehabilitation Department, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Ding Q; Department of Rare and Head and Neck Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
Ji J; Department of Rare and Head and Neck Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China.
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Source:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Sep 17; Vol. 2022, pp. 9897669. Date of Electronic Publication: 2022 Sep 17 (Print Publication: 2022).
Publication Type:
Journal Article; Retracted Publication
MeSH Terms:
Bone Neoplasms*/complications
Bone Neoplasms*/drug therapy
Cancer Pain*/drug therapy
Drug Tolerance*
Morphine*/adverse effects
Morphine*/therapeutic use
Receptors, N-Methyl-D-Aspartate*/genetics
Receptors, N-Methyl-D-Aspartate*/metabolism
Sesquiterpenes*/pharmacology
Sesquiterpenes*/therapeutic use
Adenosine Monophosphate/metabolism ; Animals ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Humans ; Rats
Academic Journal
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Title:
The role of UDP-glycosyltransferases in xenobioticresistance.
Authors:
Dimunová D; Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
Matoušková P; Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
Podlipná R; Laboratory of Plant Biotechnologies, Institute of Experimental Botany, Czech Academy of Sciences, Praha, Czech Republic.
Boušová I; Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
Skálová L; Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
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Source:
Drug metabolism reviews [Drug Metab Rev] 2022 Aug; Vol. 54 (3), pp. 282-298. Date of Electronic Publication: 2022 Jun 12.
Publication Type:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance*
Drug Tolerance*
Glycosyltransferases*/chemistry
Glycosyltransferases*/genetics
Glycosyltransferases*/metabolism
Uridine Diphosphate*/classification
Uridine Diphosphate*/genetics
Uridine Diphosphate*/metabolism
Xenobiotics*/metabolism
Xenobiotics*/toxicity
Animals ; Humans ; Phylogeny
Academic Journal
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Title:
Comparing Low Volume Versus Conventional Volume of Polyethylene Glycol for Bowel Preparation during Colonoscopy: A Randomised Controlled Trial.
Authors:
Muhammad Faeid OTHMAN
Andee Dzulkarnaen ZAKARIA
Maya Mazuwin YAHYA
Mohd Nizam MD HASHIM
Wan Mokhzani WAN MOKHTER
Wan Zainira WAN ZAIN
Ikhwan Sani MOHAMAD
Mohd Shahrulsalam MOHD SHAH
Syed Hassan SYED ABD AZIZ
Mohd Nasrullah NIK AB KADIR
Zaidi ZAKARIA
Pak-Kai WONG, Michael
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Source:
Malaysian Journal of Medical Sciences. 2023, Vol. 30 Issue 5, p106-115. 10p.
Academic Journal
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Title:
Lenalidomide plus Dexamethasone Combination as First-Line Oral Therapy of Multiple Myeloma Patients: A Unicentric Real-Life Study.
Authors:
Del Fabro, Vittorio (AUTHOR)
Di Giorgio, Mary Ann (AUTHOR)
Leotta, Valerio (AUTHOR)
Duminuco, Andrea (AUTHOR)
Bellofiore, Claudia (AUTHOR)
Markovic, Uros (AUTHOR)
Romano, Alessandra (AUTHOR)
Bulla, Anna (AUTHOR)
Curto Pelle, Angelo (AUTHOR)
Elia, Federica (AUTHOR)
Di Raimondo, Francesco (AUTHOR)
Conticello, Concetta (AUTHOR)
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Source:
Cancers. Aug2023, Vol. 15 Issue 16, p4036. 17p.
Academic Journal
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Title:
mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications.
Authors:
Wang YS; Institute of Cellular and Organismic Biology, Academia Sinica, No. 128, Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan.
Kumari M; Institute of Cellular and Organismic Biology, Academia Sinica, No. 128, Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan.
Chen GH; Biomedical Translation Research Center (BioTReC), Academia Sinica, Taipei, 11571, Taiwan.
Hong MH; Biomedical Translation Research Center (BioTReC), Academia Sinica, Taipei, 11571, Taiwan.
Yuan JP; Biomedical Translation Research Center (BioTReC), Academia Sinica, Taipei, 11571, Taiwan.
Tsai JL; Institute of Cellular and Organismic Biology, Academia Sinica, No. 128, Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan.
Wu HC; Institute of Cellular and Organismic Biology, Academia Sinica, No. 128, Academia Road, Section 2, Nankang, Taipei, 11529, Taiwan. .; Biomedical Translation Research Center (BioTReC), Academia Sinica, Taipei, 11571, Taiwan. .
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Source:
Journal of biomedical science [J Biomed Sci] 2023 Oct 07; Vol. 30 (1), pp. 84. Date of Electronic Publication: 2023 Oct 07.
Publication Type:
Journal Article; Review
MeSH Terms:
COVID-19*/prevention & control
Nanoparticles*/therapeutic use
Humans ; COVID-19 Vaccines/therapeutic use ; Drug Tolerance ; RNA, Messenger/genetics ; RNA, Messenger/therapeutic use ; mRNA Vaccines
Academic Journal
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Title:
High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications.
Authors:
Murtha AN; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America.; Department of Microbiology, Cornell University, Ithaca, New York, United States of America.
Kazi MI; Department of Biology, University of Texas Arlington, Arlington, Texas, United States of America.
Schargel RD; Department of Biology, University of Texas Arlington, Arlington, Texas, United States of America.
Cross T; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America.; Department of Microbiology, Cornell University, Ithaca, New York, United States of America.
Fihn C; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota, United States of America.
Cattoir V; Department of Clinical Microbiology and National Reference Center for Antimicrobial Resistance (Lab Enterococci), Rennes University Hospital, Rennes, France; Inserm Unit U1230, University of Rennes 1, Rennes, France.
Carlson EE; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota, United States of America.; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, United States of America.; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America.; Department of Molecular Pharmacology and Therapeutics, University of Minnesota, Minneapolis, Minnesota, United States of America.
Boll JM; Department of Biology, University of Texas Arlington, Arlington, Texas, United States of America.
Dörr T; Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America.; Department of Microbiology, Cornell University, Ithaca, New York, United States of America.; Cornell Institute of Host-Microbe Interactions and Disease, Cornell University, Ithaca, New York, United States of America.
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Source:
PLoS pathogens [PLoS Pathog] 2022 Feb 07; Vol. 18 (2), pp. e1010307. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).
Publication Type:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Drug Tolerance*
Bacterial Proteins/*metabolism
Carbapenems/*pharmacology
Enterobacter cloacae/*drug effects
Enterobacter cloacae/*metabolism
Lipopolysaccharides/*metabolism
Anti-Bacterial Agents/pharmacology ; Antimicrobial Peptides/pharmacology ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Colistin/pharmacology ; Enterobacter cloacae/genetics ; Gene Expression Regulation ; Histidine Kinase/antagonists & inhibitors ; Humans ; Lipid A/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Microbial Sensitivity Tests
Academic Journal
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Title:
Real-Life Impact of Drug Toxicity on Dolutegravir Tolerability: Clinical Practice Data from a Multicenter Italian Cohort.
Authors:
Ciccullo A; Infectious Diseases Unit, San Salvatore Hospital, 67100 L'Aquila, Italy.
Baldin G; Mater Olbia Hospital, 07026 Olbia, Italy.; Infectious Diseases Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Borghi V; Infectious and Tropical Diseases Unit, Azienda Ospedaliero Universitaria di Modena, 41125 Modena, Italy.
Lagi F; Infectious and Tropical Diseases Unit, Careggi University Hospital, 50134 Florence, Italy.
Latini A; Infectious Dermatology and Allergology Unit, IFO S. Gallicano Institute (IRCCS), 00144 Rome, Italy.
d'Ettorre G; Department of Public Health and Infectious Diseases, Azienda Policlinico Umberto I, 00185 Rome, Italy.
Oreni L; Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, 20157 Milan, Italy.
Fusco P; Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, 'Magna Graecia' University of Catanzaro, 88100 Catanzaro, Italy.
Capetti A; 1st Division of Infectious Diseases, Luigi Sacco University Hospital, 20157 Milan, Italy.
Fabbiani M; Infectious Diseases Unit, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Giacomelli A; Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, 20157 Milan, Italy.
Grimaldi A; Infectious Diseases Unit, San Salvatore Hospital, 67100 L'Aquila, Italy.
Madeddu G; Unit of Infectious Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.
Sterrantino G; Infectious and Tropical Diseases Unit, Careggi University Hospital, 50134 Florence, Italy.
Mussini C; Infectious and Tropical Diseases Unit, Azienda Ospedaliero Universitaria di Modena, 41125 Modena, Italy.
Di Giambenedetto S; Infectious Diseases Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.; Department of Safety and Bioethics, Catholic University of the Sacred Heart, 00168 Rome, Italy.
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Source:
Viruses [Viruses] 2022 Jan 17; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 17.
Publication Type:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Tolerance*
HIV Infections/*drug therapy
HIV Integrase Inhibitors/*toxicity
Heterocyclic Compounds, 3-Ring/*toxicity
Oxazines/*toxicity
Piperazines/*toxicity
Pyridones/*toxicity
Adult ; Anti-HIV Agents/therapeutic use ; Anti-HIV Agents/toxicity ; Cohort Studies ; Female ; HIV Infections/epidemiology ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Oxazines/therapeutic use ; Piperazines/therapeutic use ; Pyridones/therapeutic use
Academic Journal
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Title:
Evaluation of the safety, tolerability, and pharmacokinetics of RO7049389 in healthy Chinese volunteers.
Authors:
Wu X; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Feng S; Pharmaceutical Sciences, Roche Innovation Center Shanghai, Shanghai, China.
Zhang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Zhang W; Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Zhang Y; Pharmaceutical Sciences, Roche Innovation Center Shanghai, Shanghai, China.
Zhu M; I2O DTA, Roche Innovation Center Shanghai, Shanghai, China.
Triyatni M; Early Development Safety, Roche Pharma, Basel, Switzerland.
Zhao N; Biostatistics, Roche Pharma Product Development Shanghai, Shanghai, China.
Bo Q; I2O DTA, Roche Innovation Center Shanghai, Shanghai, China.
Jin Y; Pharmaceutical Sciences, Roche Innovation Center Shanghai, Shanghai, China.
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Source:
Clinical and translational science [Clin Transl Sci] 2022 Jan; Vol. 15 (1), pp. 195-203. Date of Electronic Publication: 2021 Sep 25.
Publication Type:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Dose-Response Relationship, Drug*
Drug Tolerance*
Healthy Volunteers*
Safety*
Antiviral Agents/*pharmacokinetics
Adolescent ; Adult ; China ; Double-Blind Method ; Female ; Hepatitis B, Chronic/drug therapy ; Humans ; Male ; Middle Aged ; Young Adult
Academic Journal
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Title:
Clinical Trial on the Safety and Tolerability of Personalized Cancer Vaccines Using Human Platelet Lysate-Induced Antigen-Presenting Cells.
Authors:
Koya, Terutsugu (AUTHOR)
Yoshida, Kenichi (AUTHOR)
Togi, Misa (AUTHOR)
Niida, Yo (AUTHOR)
Togi, Sumihito (AUTHOR)
Ura, Hiroki (AUTHOR)
Mizuta, Shuichi (AUTHOR)
Kato Jr., Tomohisa (AUTHOR)
Yamada, Sohsuke (AUTHOR)
Shibata, Takeo (AUTHOR)
Liu, Yi-Chang (AUTHOR)
Yuan, Shyng-Shiou (AUTHOR)
Wu, Deng-Chyang (AUTHOR)
Kobayashi, Hirohito (AUTHOR)
Utsugisawa, Taiju (AUTHOR)
Kanno, Hitoshi (AUTHOR)
Shimodaira, Shigetaka (AUTHOR)
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Source:
Cancers. Jul2023, Vol. 15 Issue 14, p3627. 15p.
Academic Journal
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Showing 1-20 from 8779 results

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