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Wyszukujesz frazę ""Duan, Dongsheng"" wg kryterium: Autor

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Wyświetlanie 1-20 z 28
Tytuł:
Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models
Autorzy:
Hakim, Chady H.Aff1, Aff2
Kumar, Sandeep R. P.Aff3, Aff4
Pérez-López, Dennis O.
Wasala, Nalinda B.
Zhang, DongAff5, Aff6, Aff7
Yue, Yongping
Teixeira, James
Pan, Xiufang
Zhang, Keqing
Million, Emily D.
Nelson, Christopher E.Aff8, Aff9
Metzger, Samantha
Han, Jin
Louderman, Jacqueline A.
Schmidt, FlorianAff10, Aff11, Aff12
Feng, Feng
Grimm, DirkAff10, Aff11, Aff12
Smith, Bruce F.Aff13, Aff14
Yao, Gang
Yang, N. Nora
Gersbach, Charles A.Aff8, Aff9, Aff16
Chen, Shi-jieAff5, Aff6, Aff7
Herzog, Roland W.Aff3, Aff4
Duan, DongshengAff1, Aff15, Aff17, Aff18, IDs41467021268307_cor24
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Źródło:
Nature Communications. 12(1)
Czasopismo naukowe
Szczegóły
Tytuł:
A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after acute exercise.
Autorzy:
Kwak SE; Muscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America.
Zheng A; Muscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America.
Arias EB; Muscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America.
Wang H; Muscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America.
Pan X; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Yue Y; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Duan D; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Neurology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Biomedical, Biological & Chemical Engineering, College of Engineering, University of Missouri, Columbia, Missouri, United States of America.
Cartee GD; Muscle Biology Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America.; Institute of Gerontology, University of Michigan, Ann Arbor, Michigan, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Jan 30; Vol. 19 (1), pp. e0295964. Date of Electronic Publication: 2024 Jan 30 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Glycogen*/metabolism
Physical Conditioning, Animal*/physiology
Rats ; Animals ; Glucose/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Models, Genetic ; Muscle, Skeletal/physiology ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; RNA, Small Interfering/metabolism ; Insulin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Widespread severe myodegeneration in a compound heterozygote female dog with dystrophin deficiency.
Autorzy:
Fortin JS; Veterinary Medical Diagnostic Laboratory, University of Missouri, Columbia, MO, USA.
Hakim CH; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.; National Center for Advancing Translational Sciences, NIH, Bethesda, MD, USA.
Korte S; Office of Animal Resources, University of Missouri, Columbia, MO, USA.
Yang NN; National Center for Advancing Translational Sciences, NIH, Bethesda, MD, USA.
Fitzgerald SD; Veterinary Diagnostic Laboratory, Michigan State University, Lansing, MI, USA.
Johnson GC; Veterinary Medical Diagnostic Laboratory, University of Missouri, Columbia, MO, USA.
Smith BF; Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.
Duan D; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, USA.; Department of Neurology, School of Medicine, University of Missouri, Columbia, MO, USA.; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.; Department of Biomedical, Biological & Chemical Engineering, College of Engineering, University of Missouri, Columbia, MO, USA.
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Źródło:
Veterinary medicine and science [Vet Med Sci] 2021 May; Vol. 7 (3), pp. 654-659. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Dog Diseases/*genetics
Dystrophin/*deficiency
Muscular Dystrophies/*genetics
Animals ; Dogs ; Fatal Outcome ; Female ; Heterozygote
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sensitive and reliable evaluation of single-cut sgRNAs to restore dystrophin by a GFP-reporter assay.
Autorzy:
Lyu P; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.
Yoo KW; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.
Yadav MK; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.
Atala A; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.
Aartsma-Rus A; Leiden University Medical Center, Leiden, The Netherlands.
Putten MV; Leiden University Medical Center, Leiden, The Netherlands.
Duan D; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.
Lu B; Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Sep 24; Vol. 15 (9), pp. e0239468. Date of Electronic Publication: 2020 Sep 24 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Exons/*genetics
Genetic Therapy/*methods
Muscular Dystrophy, Duchenne/*genetics
Reading Frames/*genetics
Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Dystrophin/genetics ; Dystrophin/metabolism ; Genes, Reporter/genetics ; Humans ; INDEL Mutation/genetics ; Muscular Dystrophy, Duchenne/metabolism ; Oligonucleotides, Antisense/metabolism ; RNA, Messenger/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Automatic characterization of stride parameters in canines with a single wearable inertial sensor.
Autorzy:
Jenkins GJ; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Bioengineering, University of Missouri, Columbia, Missouri, United States of America.
Hakim CH; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.; National Center for Advancing Translational Sciences, Bethesda, Maryland, United States of America.
Yang NN; National Center for Advancing Translational Sciences, Bethesda, Maryland, United States of America.
Yao G; Department of Bioengineering, University of Missouri, Columbia, Missouri, United States of America.
Duan D; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Bioengineering, University of Missouri, Columbia, Missouri, United States of America.; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, United States of America.; Department of Neurology, School of Medicine, University of Missouri, Columbia, Missouri, United States of America.
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Źródło:
PloS one [PLoS One] 2018 Jun 14; Vol. 13 (6), pp. e0198893. Date of Electronic Publication: 2018 Jun 14 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Monitoring, Physiologic/*instrumentation
Walking/*physiology
Wireless Technology/*instrumentation
Animals ; Automation ; Dogs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography.
Autorzy:
Hakim CH; Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO, United States of America.
Mijailovic A; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Lessa TB; Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO, United States of America.
Coates JR; Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States of America.
Shin C; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Rutkove SB; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Duan D; Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO, United States of America.; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States of America.; Department of Neurology, School of Medicine, University of Missouri, Columbia, MO, United States of America.; Department of Bioengineering, University of Missouri, Columbia, MO, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Mar 24; Vol. 12 (3), pp. e0173557. Date of Electronic Publication: 2017 Mar 24 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Body Composition/*physiology
Electromyography/*methods
Muscle, Skeletal/*physiopathology
Muscular Dystrophy, Duchenne/*diagnosis
Animals ; Biomarkers ; Disease Models, Animal ; Dogs ; Electric Impedance ; Muscular Dystrophy, Duchenne/physiopathology ; Severity of Illness Index
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Autorzy:
Nelson CE; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Hakim CH; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, USA.
Ousterout DG; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Thakore PI; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Moreb EA; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Castellanos Rivera RM; Gene Therapy Center, Departments of Genetics, Biochemistry and Biophysics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Madhavan S; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
Pan X; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, USA.
Ran FA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Society of Fellows, Harvard University, Cambridge, MA, USA.
Yan WX; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Graduate Program in Biophysics, Harvard Medical School, Boston, MA, USA. Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA, USA.
Asokan A; Gene Therapy Center, Departments of Genetics, Biochemistry and Biophysics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA. McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Duan D; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, USA. Department of Neurology, University of Missouri, Columbia, MO, USA.
Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA. Center for Genomic and Computational Biology, Duke University, Durham, NC, USA. Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2016 Jan 22; Vol. 351 (6271), pp. 403-7. Date of Electronic Publication: 2015 Dec 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
CRISPR-Cas Systems*
Dystrophin/*genetics
Exons/*genetics
Genetic Therapy/*methods
Muscle, Skeletal/*metabolism
Muscular Dystrophy, Duchenne/*therapy
Animals ; Clustered Regularly Interspaced Short Palindromic Repeats ; Dependovirus ; Disease Models, Animal ; Male ; Mice ; Mice, Inbred mdx ; Muscular Dystrophy, Duchenne/genetics ; Sequence Deletion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot.
Autorzy:
Kodippili K; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Vince L; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Shin JH; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Yue Y; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Morris GE; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, and Keele University, Keele, Staffordshire, United Kingdom.
McIntosh MA; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Duan D; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Feb 07; Vol. 9 (2), pp. e88280. Date of Electronic Publication: 2014 Feb 07 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal/*metabolism
Dystrophin/*immunology
Epitopes/*immunology
Muscular Dystrophy, Animal/*immunology
Muscular Dystrophy, Duchenne/*immunology
Animals ; Blotting, Western ; Disease Models, Animal ; Dogs ; Exons ; Immunohistochemistry ; Mice ; Muscular Dystrophy, Animal/metabolism ; Muscular Dystrophy, Duchenne/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring.
Autorzy:
Shin JH; Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, Missouri, United States of America.
Greer B
Hakim CH
Zhou Z
Chung YC
Duan Y
He Z
Duan D
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (3), pp. e59875. Date of Electronic Publication: 2013 Mar 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gait/*physiology
Monitoring, Physiologic/*veterinary
Muscular Dystrophy, Animal/*physiopathology
Muscular Dystrophy, Duchenne/*physiopathology
Animals ; Dogs ; Extremities/physiopathology ; Motor Activity/physiology ; Phenotype ; Range of Motion, Articular/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy.
Autorzy:
Yang HT; Department of Biomedical Sciences, College of Veterinary Medicine, The University of Missouri, Columbia, Missouri, United States of America.
Shin JH
Hakim CH
Pan X
Terjung RL
Duan D
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (9), pp. e44438. Date of Electronic Publication: 2012 Sep 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Dystrophin/*deficiency
Muscle Weakness/*pathology
Muscle, Skeletal/*physiopathology
Muscular Dystrophy, Duchenne/*physiopathology
Analysis of Variance ; Animals ; Biomechanical Phenomena ; Blood Flow Velocity ; Blood Pressure ; Dogs ; Histological Techniques ; Image Processing, Computer-Assisted ; Muscle Weakness/etiology ; Muscular Dystrophy, Duchenne/complications
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice.
Autorzy:
Shin JH; Department of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO, USA.
Bostick B
Yue Y
Hajjar R
Duan D
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Źródło:
Journal of translational medicine [J Transl Med] 2011 Aug 11; Vol. 9, pp. 132. Date of Electronic Publication: 2011 Aug 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Electrocardiography*
Gene Transfer Techniques*
Genetic Therapy*
Aging/*pathology
Sarcoplasmic Reticulum Calcium-Transporting ATPases/*genetics
Sarcoplasmic Reticulum Calcium-Transporting ATPases/*therapeutic use
Animals ; Dependovirus/genetics ; Female ; Genetic Vectors/genetics ; Humans ; Mice ; Mice, Inbred mdx ; Myocardium/metabolism ; Myocardium/pathology ; Transduction, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice.
Autorzy:
Li D; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, Missouri, United States of America.
Shin JH
Duan D
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Źródło:
PloS one [PLoS One] 2011; Vol. 6 (6), pp. e21618. Date of Electronic Publication: 2011 Jun 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Dystrophin/*deficiency
Muscle, Skeletal/*metabolism
Muscle, Skeletal/*pathology
Muscular Dystrophy, Animal/*pathology
Muscular Dystrophy, Duchenne/*pathology
Nitric Oxide Synthase Type II/*deficiency
Animals ; Dystrophin/genetics ; Male ; Mice ; Mice, Knockout ; Muscular Dystrophy, Animal/genetics ; Muscular Dystrophy, Animal/metabolism ; Muscular Dystrophy, Duchenne/genetics ; Muscular Dystrophy, Duchenne/metabolism ; Nitric Oxide Synthase Type II/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 28

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