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Tytuł :
Growth hormone-releasing hormone agonists ameliorate chronic kidney disease-induced heart failure with preserved ejection fraction.
Autorzy :
Rieger AC; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Bagno LL; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Salerno A; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Florea V; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Rodriguez J; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Rosado M; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Turner D; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Dulce RA; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Takeuchi LM; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Kanashiro-Takeuchi RM; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136.
Buchwald P; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136.; Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Wanschel ACBA; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Balkan W; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136.
Schulman IH; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136.; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136.; Katz Family Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL 33136.
Schally AV; Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL 33136; .; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136.; Endocrine, Polypeptide and Cancer Institute, Veteran Affairs Medical Center, Miami, FL 33125.
Hare JM; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL 33136; .; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 26; Vol. 118 (4).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cardiotonic Agents/*pharmacology
Growth Hormone-Releasing Hormone/*agonists
Heart Failure/*drug therapy
Renal Insufficiency, Chronic/*drug therapy
Sermorelin/*analogs & derivatives
Stroke Volume/*physiology
Animals ; Blood Urea Nitrogen ; Calcium/metabolism ; Connectin/genetics ; Connectin/metabolism ; Creatinine/blood ; Disease Models, Animal ; Female ; Gene Expression Regulation ; Growth Hormone-Releasing Hormone/genetics ; Growth Hormone-Releasing Hormone/metabolism ; Heart Failure/etiology ; Heart Failure/genetics ; Heart Failure/pathology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Natriuretic Peptide, Brain/blood ; Natriuretic Peptide, Brain/genetics ; Nephrectomy/methods ; Peptide Fragments/blood ; Peptide Fragments/genetics ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/genetics ; Renal Insufficiency, Chronic/pathology ; Sermorelin/pharmacology ; Swine
Czasopismo naukowe
Tytuł :
NOX Inhibition Improves β-Adrenergic Stimulated Contractility and Intracellular Calcium Handling in the Aged Rat Heart.
Autorzy :
Valdés Á; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
Treuer AV; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
Barrios G; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
Ponce N; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
Fuentealba R; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
Dulce RA; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA. .
González DR; Departamento de Ciencias Básicas Biomédicas, Facultad Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2018 Aug 15; Vol. 19 (8). Date of Electronic Publication: 2018 Aug 15.
Typ publikacji :
Journal Article
MeSH Terms :
Acetophenones/*pharmacology
Adrenergic beta-Agonists/*pharmacology
Benzoxazoles/*pharmacology
Calcium/*metabolism
Heart/*drug effects
Isoproterenol/*pharmacology
Myocardial Contraction/*drug effects
NADPH Oxidases/*antagonists & inhibitors
Triazoles/*pharmacology
Aging/drug effects ; Animals ; Cells, Cultured ; Enzyme Inhibitors/pharmacology ; Female ; Heart/physiology ; Male ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; NADPH Oxidases/metabolism ; Rats
Czasopismo naukowe
Tytuł :
S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca2+)Sensitivity in Intact Cardiomyocytes.
Autorzy :
Figueiredo-Freitas C; 1 Department of Biomedical Sciences, College of Medicine, Florida State University , Tallahassee, Florida.; 2 Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .; 3 Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami , Miami, Florida.
Dulce RA; 4 Interdisciplinary Stem Cell Institute, University of Miami , Miami, Florida.
Foster MW; 5 Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center , Durham, North Carolina.; 6 Proteomics and Metabolomics Shared Resource, Duke University Medical Center , Durham, North Carolina.
Liang J; 3 Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami , Miami, Florida.
Yamashita AM; 2 Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
Lima-Rosa FL; 2 Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
Thompson JW; 6 Proteomics and Metabolomics Shared Resource, Duke University Medical Center , Durham, North Carolina.
Moseley MA; 6 Proteomics and Metabolomics Shared Resource, Duke University Medical Center , Durham, North Carolina.
Hare JM; 4 Interdisciplinary Stem Cell Institute, University of Miami , Miami, Florida.
Nogueira L; 2 Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
Sorenson MM; 2 Instituto de Bioquímica Médica Leopoldo de Meis (IBqM), Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
Pinto JR; 1 Department of Biomedical Sciences, College of Medicine, Florida State University , Tallahassee, Florida.; 3 Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami , Miami, Florida.
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Źródło :
Antioxidants & redox signaling [Antioxid Redox Signal] 2015 Nov 01; Vol. 23 (13), pp. 1017-34.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Cysteine/*analogs & derivatives
Muscle Proteins/*metabolism
Myocytes, Cardiac/*metabolism
Myofibrils/*metabolism
S-Nitrosothiols/*metabolism
Animals ; Ca(2+) Mg(2+)-ATPase/metabolism ; Cells, Cultured ; Cysteine/metabolism ; Mice, 129 Strain ; Mice, Inbred C57BL ; Myocardial Contraction ; Nitric Oxide/metabolism ; Oxidative Stress ; Sarcomeres
Czasopismo naukowe
Tytuł :
S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction.
Autorzy :
Hatzistergos KE; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Paulino EC; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Dulce RA; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Takeuchi LM; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Bellio MA; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.) Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL (M.A.B., R.M.K.T., J.M.H.).
Kulandavelu S; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Cao Y; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.).
Balkan W; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.) Department of Medicine, University of Miami Miller School of Medicine, Miami, FL (W.B., J.M.H.).
Kanashiro-Takeuchi RM; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.) Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL (M.A.B., R.M.K.T., J.M.H.).
Hare JM; Interdisciplinary Stem Cell Institute, University of Miami, FL (K.E.H., E.C.P., R.A.D., L.M.T., M.A.B., S.K., Y.C., W.B., R.M.K.T., J.M.H.) Department of Medicine, University of Miami Miller School of Medicine, Miami, FL (W.B., J.M.H.) Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL (M.A.B., R.M.K.T., J.M.H.).
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Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2015 Jul 15; Vol. 4 (7). Date of Electronic Publication: 2015 Jul 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Proliferation*
Regeneration*
Adult Stem Cells/*enzymology
Alcohol Dehydrogenase/*deficiency
Myocardial Infarction/*enzymology
Myocytes, Cardiac/*enzymology
Adult Stem Cells/pathology ; Alcohol Dehydrogenase/genetics ; Animals ; Biomarkers/metabolism ; Calcium Signaling ; Cells, Cultured ; Disease Models, Animal ; Homozygote ; Leukocyte Common Antigens/deficiency ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Myocardial Contraction ; Myocardial Infarction/genetics ; Myocardial Infarction/pathology ; Myocardial Infarction/physiopathology ; Myocytes, Cardiac/pathology ; Neovascularization, Physiologic ; Phenotype ; Proto-Oncogene Proteins c-kit/metabolism ; Stroke Volume ; Time Factors
Czasopismo naukowe
Tytuł :
Interaction between neuronal nitric oxide synthase signaling and temperature influences sarcoplasmic reticulum calcium leak: role of nitroso-redox balance.
Autorzy :
Dulce RA; From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.
Mayo V; From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.
Rangel EB; From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.
Balkan W; From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL.
Hare JM; From the Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL. .
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Źródło :
Circulation research [Circ Res] 2015 Jan 02; Vol. 116 (1), pp. 46-55. Date of Electronic Publication: 2014 Oct 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Temperature*
Calcium/*metabolism
Nitric Oxide Synthase Type I/*deficiency
Sarcoplasmic Reticulum/*metabolism
Signal Transduction/*physiology
Animals ; Mice ; Mice, Inbred C57BL ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Hypotonic swelling promotes nitric oxide release in cardiac ventricular myocytes: impact on swelling-induced negative inotropic effect.
Autorzy :
Gonano LA; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina.
Morell M; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina.
Burgos JI; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina.
Dulce RA; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
De Giusti VC; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina.
Aiello EA; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina.
Hare JM; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Vila Petroff M; Centro de Investigaciones Cardiovasculares, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 60 y 120, La Plata 1900, Argentina .
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Źródło :
Cardiovascular research [Cardiovasc Res] 2014 Dec 01; Vol. 104 (3), pp. 456-66. Date of Electronic Publication: 2014 Oct 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Osmoregulation*
Cytoskeleton/*physiology
Myocytes, Cardiac/*physiology
Nitric Oxide/*metabolism
Animals ; Cyclic GMP/metabolism ; Male ; Mice, Inbred C57BL ; Myocardial Contraction ; Nitric Oxide Synthase Type I/metabolism ; Rats, Wistar
Czasopismo naukowe
Tytuł :
NADPH oxidase-2 inhibition restores contractility and intracellular calcium handling and reduces arrhythmogenicity in dystrophic cardiomyopathy.
Autorzy :
Gonzalez DR; Departamento de Ciencias Basicas Biomedicas, Facultad de Ciencias de la Salud, Universidad de Talca, Talca, Chile; and.
Treuer AV; Departamento de Ciencias Basicas Biomedicas, Facultad de Ciencias de la Salud, Universidad de Talca, Talca, Chile; and.
Lamirault G; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida.
Mayo V; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida.
Cao Y; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida.
Dulce RA; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida.
Hare JM; Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, Florida .
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2014 Sep 01; Vol. 307 (5), pp. H710-21. Date of Electronic Publication: 2014 Jul 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Myocardial Contraction*
Arrhythmias, Cardiac/*metabolism
Cardiomyopathies/*metabolism
Membrane Glycoproteins/*metabolism
NADPH Oxidases/*metabolism
Animals ; Benzoxazoles/pharmacology ; Calcium/metabolism ; Cardiomyopathies/physiopathology ; Membrane Glycoproteins/antagonists & inhibitors ; Membrane Glycoproteins/genetics ; Mice ; Mice, Inbred mdx ; NADPH Oxidase 2 ; NADPH Oxidases/antagonists & inhibitors ; NADPH Oxidases/genetics ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Oxidative Stress ; Sarcoplasmic Reticulum/metabolism ; Triazoles/pharmacology
Czasopismo naukowe
Tytuł :
Long term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathy.
Autorzy :
Dweck D; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Sanchez-Gonzalez MA; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300,; Family Institute, Florida State University, Tallahassee, Florida 32306.
Chang AN; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9040.
Dulce RA; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, and.
Badger CD; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Koutnik AP; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Ruiz EL; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Griffin B; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Liang J; Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Kabbaj M; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Fincham FD; Family Institute, Florida State University, Tallahassee, Florida 32306.
Hare JM; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, and.
Overton JM; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300.
Pinto JR; Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida 32306-4300,. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2014 Aug 15; Vol. 289 (33), pp. 23097-23111. Date of Electronic Publication: 2014 Jun 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Diastole*
Cardiomyopathy, Hypertrophic/*metabolism
Cyclic AMP-Dependent Protein Kinases/*metabolism
Myocytes, Cardiac/*metabolism
Troponin I/*metabolism
Animals ; Cardiomyopathy, Hypertrophic/genetics ; Cyclic AMP-Dependent Protein Kinases/genetics ; Disease Models, Animal ; Male ; Mice ; Mice, Transgenic ; Myocytes, Cardiac/pathology ; Phosphorylation/physiology ; Sarcoplasmic Reticulum/genetics ; Sarcoplasmic Reticulum/metabolism ; Troponin I/genetics
Czasopismo naukowe
Tytuł :
C-kit(+) cells isolated from developing kidneys are a novel population of stem cells with regenerative potential.
Autorzy :
Rangel EB; Interdisciplinary Stem Cell Institute, São Paulo, São Paulo, Brazil; Sociedade Beneficente Albert Einstein, Albert Einstein Hospital, São Paulo, São Paulo, Brazil; Division of Nephrology, Department of Medicine, Federal University of São Paulo, São Paulo, São Paulo, Brazil.
Gomes SA
Dulce RA
Premer C
Rodrigues CO
Kanashiro-Takeuchi RM
Oskouei B
Carvalho DA
Ruiz P
Reiser J
Hare JM
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Źródło :
Stem cells (Dayton, Ohio) [Stem Cells] 2013 Aug; Vol. 31 (8), pp. 1644-56.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Embryonic Stem Cells/*cytology
Embryonic Stem Cells/*enzymology
Kidney/*cytology
Kidney/*growth & development
Proto-Oncogene Proteins c-kit/*metabolism
Animals ; Animals, Newborn ; Cell Differentiation/physiology ; Female ; Kidney/embryology ; Kidney/enzymology ; Kidney Cortex/cytology ; Kidney Cortex/enzymology ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
Hydralazine and organic nitrates restore impaired excitation-contraction coupling by reducing calcium leak associated with nitroso-redox imbalance.
Autorzy :
Dulce RA; Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Yiginer O
Gonzalez DR
Goss G
Feng N
Zheng M
Hare JM
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2013 Mar 01; Vol. 288 (9), pp. 6522-33. Date of Electronic Publication: 2013 Jan 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium/*metabolism
Excitation Contraction Coupling/*drug effects
Hydralazine/*pharmacology
Myocytes, Cardiac/*metabolism
Nitroglycerin/*pharmacology
Vasodilator Agents/*pharmacology
Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Excitation Contraction Coupling/genetics ; Male ; Mice ; Mice, Knockout ; Muscle Proteins/genetics ; Muscle Proteins/metabolism ; Myocardial Contraction/drug effects ; Myocardial Contraction/genetics ; Myocytes, Cardiac/pathology ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Oxidation-Reduction/drug effects ; Rats ; Rats, Inbred WKY ; Sarcoplasmic Reticulum/metabolism ; Sarcoplasmic Reticulum/pathology
Czasopismo naukowe
Tytuł :
S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells.
Autorzy :
Gomes SA; Interdisciplinary Stem Cell Institute, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Rangel EB
Premer C
Dulce RA
Cao Y
Florea V
Balkan W
Rodrigues CO
Schally AV
Hare JM
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Feb 19; Vol. 110 (8), pp. 2834-9. Date of Electronic Publication: 2013 Jan 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neovascularization, Physiologic*
Alcohol Dehydrogenase/*physiology
Mesenchymal Stem Cells/*physiology
Alcohol Dehydrogenase/genetics ; Animals ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Wnt signalling: a mediator of the heart-bone marrow axis after myocardial injury?
Autorzy :
Dulce RA
Balkan W
Hare JM
Schulman IH
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Źródło :
European heart journal [Eur Heart J] 2012 Aug; Vol. 33 (15), pp. 1861-3. Date of Electronic Publication: 2011 Dec 23.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Bone Marrow/*metabolism
Hematopoietic Stem Cells/*physiology
Monocytes/*physiology
Myocardial Infarction/*pathology
Signal Transduction/*physiology
Wnt1 Protein/*metabolism
Animals ; Female ; Humans ; Male
Raport

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