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Tytuł :
[Expression of nuclear hormone receptors PPAR, LXR and RXR in the liver and lipid and glucose levels in blood in susceptible and resistant to hepatocarcinogenesis mice strains].
Autorzy :
Pivovarova EN
Baginskaia NV
Perepechaeva ML
Il'nitskaia SI
Dushkin MI
Pokaż więcej
Źródło :
Biomeditsinskaia khimiia [Biomed Khim] 2010 Jul-Aug; Vol. 56 (4), pp. 480-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Glucose/*metabolism
Lipids/*blood
Liver Neoplasms/*metabolism
Orphan Nuclear Receptors/*biosynthesis
Peroxisome Proliferator-Activated Receptors/*biosynthesis
Retinoid X Receptors/*biosynthesis
Animals ; Corticosterone/blood ; Disease Susceptibility ; Insulin/blood ; Liver Neoplasms/etiology ; Liver X Receptors ; Male ; Mice ; Mice, Inbred Strains ; Species Specificity
Czasopismo naukowe
Tytuł :
Effects of cholesterol and nuclear hormone receptor agonists on the production of transforming growth factor-beta in macrophages.
Autorzy :
Schwartz YSh; Institute of Therapy, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia. />Khoshchenko OM
Dushkin MI
Feofanova NA
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2009 Sep; Vol. 148 (3), pp. 406-9.
Typ publikacji :
Journal Article
MeSH Terms :
Macrophages/*drug effects
Macrophages/*metabolism
Receptors, Cytoplasmic and Nuclear/*agonists
Transforming Growth Factor beta/*metabolism
Alitretinoin ; Animals ; Cells, Cultured ; Cholesterol/pharmacology ; Farnesol/pharmacology ; Hydroxycholesterols/pharmacology ; Hydroxysteroids/pharmacology ; Ketocholesterols/pharmacology ; Lipopolysaccharides/pharmacology ; Liver X Receptors ; Male ; Mevalonic Acid/analogs & derivatives ; Mevalonic Acid/pharmacology ; Mice ; Mice, Inbred C57BL ; Orphan Nuclear Receptors/agonists ; Retinoid X Receptors/agonists ; Tretinoin/pharmacology
Czasopismo naukowe
Tytuł :
The content of PPAR, LXR, and RXR and the PPAR DNA-binding activity in macrophages over the course of inflammation in mice.
Autorzy :
Dushkin MI; Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. />Khoshchenko OM
Chasovsky MA
Pivovarova EN
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2009 Mar; Vol. 147 (3), pp. 345-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA/*metabolism
DNA-Binding Proteins/*metabolism
Inflammation/*metabolism
Macrophages/*metabolism
Peroxisome Proliferator-Activated Receptors/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Retinoid X Receptors/*metabolism
Animals ; Immunoblotting ; Inflammation/chemically induced ; Liver X Receptors ; Macrophages/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Orphan Nuclear Receptors ; Protein Binding/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Zymosan/pharmacology
Czasopismo naukowe
Tytuł :
In vitro accumulation of complexes of endotoxin and low-density lipoproteins by macrophages and arterial wall.
Autorzy :
Schwartz YSh; Institute of Therapy, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. />Dushkin MI
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2009 Feb; Vol. 147 (2), pp. 189-92.
Typ publikacji :
Journal Article
MeSH Terms :
Aorta/*metabolism
Lipopolysaccharides/*metabolism
Lipoproteins, LDL/*metabolism
Macrophages, Peritoneal/*metabolism
Animals ; Biological Transport/physiology ; Cells, Cultured ; In Vitro Techniques ; Protein Binding ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Cholesterol-induced stimulation of postinflammatory liver fibrosis.
Autorzy :
Schwartz YSh; Institute of Therapy, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. Russia. />Dushkin MI
Komarova NI
Vorontsova EV
Kuznetsova IS
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2008 Jun; Vol. 145 (6), pp. 692-5.
Typ publikacji :
Journal Article
MeSH Terms :
Liver/*metabolism
Liver Cirrhosis/*metabolism
Animals ; Atorvastatin ; Calcitriol/pharmacology ; Cholesterol Esters/metabolism ; Cholesterol, Dietary/administration & dosage ; Collagen/metabolism ; Gene Expression/drug effects ; Heptanoic Acids/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Liver/drug effects ; Liver/pathology ; Liver Cirrhosis/etiology ; Liver Cirrhosis/prevention & control ; Male ; Mevalonic Acid/pharmacology ; Mice ; Mice, Inbred C57BL ; Pyrroles/pharmacology ; Transforming Growth Factor beta1/genetics ; Triglycerides/metabolism ; Zymosan/pharmacology
Czasopismo naukowe
Tytuł :
Modification and clearance of low density lipoproteins during the formation of endotoxin-lipoprotein complexes.
Autorzy :
Schvartz YSh; Institute of Therapy, Siberian Division of Russian Academy of Medical Sciences; Institute of Biochemistry, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk.
Polyakov LM
Dushkin MI
Pivovarova EN
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2008 Apr; Vol. 145 (4), pp. 430-2.
Typ publikacji :
Journal Article
MeSH Terms :
Endotoxins/*metabolism
Lipoproteins/*metabolism
Lipoproteins, LDL/*pharmacokinetics
Animals ; Electrophysiology ; Endotoxins/blood ; Half-Life ; Iodine Radioisotopes/pharmacokinetics ; Lipopolysaccharides/blood ; Lipopolysaccharides/metabolism ; Lipoproteins/blood ; Lipoproteins, LDL/blood ; Lipoproteins, LDL/chemistry ; Male ; Metabolic Clearance Rate ; Multiprotein Complexes/blood ; Multiprotein Complexes/metabolism ; Protein Binding ; Protein Processing, Post-Translational/physiology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Lipid synthesis in macrophages during inflammation in vivo: effect of agonists of peroxisome proliferator activated receptors alpha and gamma and of retinoid X receptors.
Autorzy :
Posokhova EN; Institute of Internal Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Khoshchenko OM
Chasovskikh MI
Pivovarova EN
Dushkin MI
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2008 Mar; Vol. 73 (3), pp. 296-304.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Inflammation/*metabolism
Lipids/*biosynthesis
Macrophages, Peritoneal/*metabolism
Peroxisome Proliferator-Activated Receptors/*agonists
Retinoid X Receptors/*agonists
Acetic Acid/metabolism ; Animals ; Cholesterol/biosynthesis ; Cholesterol/chemistry ; Cholesterol Esters/biosynthesis ; Cholesterol Esters/chemistry ; Fatty Acids/biosynthesis ; Inflammation/chemically induced ; Lipopolysaccharides/administration & dosage ; Lipoproteins, LDL/metabolism ; Macrophages, Peritoneal/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Oleic Acid/metabolism ; PPAR alpha/agonists ; PPAR gamma/agonists ; Triglycerides/biosynthesis ; Triglycerides/chemistry ; Zymosan/administration & dosage
Czasopismo naukowe
Tytuł :
[Influence of the activation of the immune system cells on the parameters of lipid metabolism in macrophages].
Autorzy :
Dushkin MI
Perminova OM
Safina AF
Vol'skiĭ NN
Shvarts IaSh
Kozlov VA
Pokaż więcej
Transliterated Title :
Vliianie aktivatsii kletok immunnoĭ sistemy na parametry lipidnogo obmena v makrofagakh.
Źródło :
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2004 Nov-Dec (6), pp. 52-6.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Lipid Metabolism*
Macrophage Activation*
Macrophages, Peritoneal/*immunology
Animals ; Animals, Outbred Strains ; Cells, Cultured ; Cholesterol Esters/chemistry ; Cholesterol Esters/metabolism ; Coculture Techniques ; Culture Media, Conditioned/pharmacology ; Cytokines/pharmacology ; Leukocytes/immunology ; Lipids/chemistry ; Macrophages, Peritoneal/drug effects ; Macrophages, Peritoneal/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Spleen/immunology ; Triglycerides/chemistry ; Triglycerides/metabolism ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
Endotoxin-lipoprotein complex formation as a factor in atherogenesis: associations with hyperlipidemia and with lecithin:cholesterol acyltransferase activity.
Autorzy :
Schwartz YSh; Institute of Internal Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. />Dushkin MI
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2002 Jul; Vol. 67 (7), pp. 747-52.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arteriosclerosis/*blood
Hyperlipidemias/*blood
Lipopolysaccharides/*blood
Lipopolysaccharides/*metabolism
Lipoproteins/*blood
Lipoproteins/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*metabolism
Arteriosclerosis/enzymology ; Humans ; Hyperlipidemias/enzymology ; Macromolecular Substances ; Phosphatidylcholine-Sterol O-Acyltransferase/antagonists & inhibitors ; Protein Binding ; Salmonella
Czasopismo naukowe
Tytuł :
[Effect of stimulation and inhibition of macrophage functions on hypercholesterolemia in rats].
Autorzy :
Kuznetsov PO; Institute of Internal Medicine, Siberian Division of the Russian Academy of Medical Sciences, Vladimirovski st. 2a, Novosibirsk 630003, Russia.
Safina AF
Shvarts IaSh
Tsyrendorzhiev DD
Zubakhin AA
Dushkin MI
Pokaż więcej
Transliterated Title :
Vliianie stimuliatsii i ingibirovaniia funktsii makrofagov na razvitie giperkholesterinemii u krys.
Źródło :
Voprosy meditsinskoi khimii [Vopr Med Khim] 2002 Mar-Apr; Vol. 48 (2), pp. 180-8.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Cholesterol/*metabolism
Hypercholesterolemia/*metabolism
Macrophages, Peritoneal/*drug effects
Animals ; Bile Acids and Salts/metabolism ; Biological Transport ; Cholesterol/blood ; Cholesterol Esters/blood ; Depression, Chemical ; Gadolinium/pharmacology ; Hypercholesterolemia/chemically induced ; Kupffer Cells/drug effects ; Kupffer Cells/pathology ; Lipoproteins, LDL/blood ; Lipoproteins, VLDL/blood ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Macrophages, Peritoneal/metabolism ; Male ; Phagocytosis/drug effects ; Prodigiozan/pharmacology ; Rats ; Rats, Wistar ; Sterol Esterase/metabolism ; Sterol O-Acyltransferase/metabolism ; Stimulation, Chemical ; Zymosan/pharmacology
Czasopismo naukowe
Tytuł :
[Effect of modified low density lipoproteins on humoral immune response and functional activity of macrophages in mice].
Autorzy :
Poveshchenko AF; Institute of Clinical Immunology, Institute of Therapy, Siberian Branch, Russian Acad. Med. Sci., Novosibirsk, Russia.
Perminova OM
Dushkin MI
Kuznetsov PO
Vol'skiĭ NN
Kozlov VA
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Transliterated Title :
Vliianie modifitsirovannykh lipoproteinov nizkoĭ plotnosti na gumoral'nyĭ immunyĭ otvet i funktsional'nuiu aktivnost' makrofagov myshi.
Źródło :
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2002 Jan-Feb (1), pp. 57-60.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Antibody Formation/*drug effects
Lipoproteins, LDL/*immunology
Lipoproteins, LDL/*pharmacology
Macrophage Activation/*immunology
Adjuvants, Immunologic/pharmacology ; Animals ; Macrophage Activation/drug effects ; Male ; Mice
Czasopismo naukowe
Tytuł :
[Effect of 25-hydroxycholesterol and progesterone on esterification of cholesterol, viscosity, and protein-lipid interactions in macrophage membranes].
Autorzy :
Dushkin MI
Kolosova NG
Safina AF
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Transliterated Title :
Vliianie 25-gidroksikholesterina i progesterona na ésterifikatsiiu kholesterina, viazkost' i belkovo-lipidnye vzaimodeĭstviia membran v makrofagakh.
Źródło :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 2000 Feb; Vol. 129 (2), pp. 145-8.
Typ publikacji :
Journal Article
MeSH Terms :
Cholesterol Esters/*biosynthesis
Hydroxycholesterols/*pharmacology
Macrophages, Peritoneal/*metabolism
Membrane Lipids/*metabolism
Membrane Proteins/*metabolism
Progesterone/*pharmacology
Animals ; Fluorometry ; In Vitro Techniques ; Macrophages, Peritoneal/ultrastructure ; Mice ; Mice, Inbred C57BL ; Viscosity
Czasopismo naukowe
Tytuł :
[Formation of SiO2-induced granulomas in mice of various strains].
Autorzy :
Shvarts IaSh
Zubakhin AA
Ustinov AS
Dushkin MI
Ragino IuI
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Transliterated Title :
Formirovanie SiO2-indutsirovannykh granulem u mysheĭ raznykh liniĭ.
Źródło :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 2000 Jan; Vol. 129 (1), pp. 20-4.
Typ publikacji :
Journal Article
MeSH Terms :
Granuloma, Foreign-Body/*pathology
Silicon Dioxide/*toxicity
Animals ; Granuloma ; Granuloma, Foreign-Body/etiology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C3H ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Organ Specificity ; Species Specificity
Czasopismo naukowe
Tytuł :
[The oxidation resistance of the blood serum heparin-precipitated beta-lipoproteins in myocardial infarct patients].
Autorzy :
Ragino IuI
Rabko AV
Dushkin MI
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Transliterated Title :
Rezistentnost' k okisleniiu gerparinosazhdennykh beta-lipoproteinov syvorotki krovi u bol'nykh infarktom miokarda.
Źródło :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 1999 Jul (7), pp. 3-4.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Lipid Peroxidation*
Lipoproteins, LDL/*blood
Myocardial Infarction/*blood
Adult ; Aged ; Heparin ; Humans ; Indicators and Reagents ; Lipoproteins, LDL/drug effects ; Lipoproteins, LDL/isolation & purification ; Male ; Middle Aged ; Recurrence ; Time Factors
Czasopismo naukowe
Tytuł :
[Effects of hydroxysterols on expression of inflammatory cytokine genes and their level in macrophages tolerant to endotoxin].
Autorzy :
Dushkin MI
Vereshchagin EI
Grebenshchikov AIu
Safina AF
Shvarts IaSh
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Transliterated Title :
Vliianie oksisterolov na ékspressiiu genov vospalitel'nykh tsitokinov i ikh soderzhanie v makrofagakh, torerantnykh k éndotoksinu.
Źródło :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1999 Jan; Vol. 127 (1), pp. 71-4.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Hydroxycholesterols/*metabolism
Inflammation/*metabolism
Interleukin-1/*metabolism
Ketocholesterols/*metabolism
Macrophages, Peritoneal/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Cells, Cultured ; Hydroxycholesterols/pharmacology ; Interleukin-1/genetics ; Ketocholesterols/pharmacology ; Lipopolysaccharides/toxicity ; Macrophages, Peritoneal/drug effects ; Male ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
[Lowering of resistance to oxidation of VLDL lipoproteins and some subfractions of LDL lipoproteins in patients with non-insulin-dependent diabetes mellitus].
Autorzy :
Ragino IuI
Dushkin MI
Nikitin IuP
Pokaż więcej
Transliterated Title :
Snizheniie rezistentnosti k okisleniiu lipoproteinov ochen' nizkoĭ plotnosti i otdel'nykh subfraktsiĭ lipoproteinov nizkoĭ plotnosti u bol'nykh insulinnezavisimym sakharnym diabetom.
Źródło :
Terapevticheskii arkhiv [Ter Arkh] 1999; Vol. 71 (4), pp. 52-5.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Diabetes Mellitus, Type 1/*blood
Lipid Peroxidation/*physiology
Lipoproteins, LDL/*blood
Lipoproteins, VLDL/*blood
Adult ; Arteriosclerosis/blood ; Arteriosclerosis/etiology ; Biomarkers/blood ; Cholesterol/blood ; Diabetes Mellitus, Type 1/complications ; Disease Progression ; Female ; Fluorometry ; Humans ; Male ; Middle Aged ; Risk Factors ; Ultracentrifugation
Czasopismo naukowe
Tytuł :
[The oxidation resistance of heparin-precipitated blood serum beta-lipoproteins in ischemic heart disease].
Autorzy :
Ragino IuI
Dushkin MI
Pokaż więcej
Transliterated Title :
Rezistentnost' k okisleniiu geparinosazhdennykh beta-lipoproteinov syvorotki krovi pri ishemicheskoĭ bolezni serdtsa.
Źródło :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 1998 Nov (11), pp. 3-5.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Lipid Peroxidation*/drug effects
Lipoproteins, LDL/*blood
Myocardial Ischemia/*blood
Adult ; Angina Pectoris/blood ; Heparin/pharmacology ; Humans ; Lipoproteins, LDL/drug effects ; Lipoproteins, LDL/isolation & purification ; Male ; Middle Aged ; Physical Exertion
Czasopismo naukowe
Tytuł :
[A simple method of studying oxidation resistance of heparin-precipitated blood beta lipoproteins].
Autorzy :
Ragino IuI
Dushkin MI
Pokaż więcej
Transliterated Title :
Prostoĭ metod issledovaniia rezistentnosti k okisleniiu geparinosazhdennykh beta-lipoproteinov syvorotki krovi.
Źródło :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 1998 Mar (3), pp. 6-8.
Typ publikacji :
Comparative Study; English Abstract; Journal Article
MeSH Terms :
Lipid Peroxidation*/drug effects
Coronary Disease/*blood
Lipoproteins, LDL/*blood
Adult ; Anticoagulants/pharmacology ; Copper/pharmacology ; Data Interpretation, Statistical ; Heparin/pharmacology ; Humans ; Lipoproteins, LDL/metabolism ; Male ; Middle Aged ; Ultracentrifugation
Czasopismo naukowe
Tytuł :
[Effect of oxidized cholesterol derivatives on lymphokine stimulated differentiation of macrophages and primary allogenic mixed human lymphocyte culture].
Autorzy :
Musatov MI
Dushkin MI
Vol'skiĭ NN
Perminova OM
Konenkov VI
Kozlov VA
Pokaż więcej
Transliterated Title :
Vliianie okislennykh proizvodnykh kholesterina na limfokinstimulirovannuiu differentsirovku makrofagov i pervichnuiu allogennuiu smeshannuiu kul'turu limfotsitov cheloveka.
Źródło :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1997 Dec; Vol. 124 (12), pp. 655-7.
Typ publikacji :
Journal Article
MeSH Terms :
Hydroxycholesterols/*pharmacology
Ketocholesterols/*pharmacology
Lymphocytes/*drug effects
Lymphokines/*immunology
Macrophages/*drug effects
Adult ; Antigen-Presenting Cells/cytology ; Antigen-Presenting Cells/drug effects ; Antigen-Presenting Cells/immunology ; Cell Adhesion/immunology ; Cell Differentiation/drug effects ; Cell Differentiation/immunology ; Cell Division/drug effects ; Cell Division/immunology ; Cells, Cultured ; Female ; HLA-DR Antigens/immunology ; Humans ; Lymphocyte Activation/immunology ; Lymphocyte Culture Test, Mixed ; Lymphocytes/cytology ; Lymphocytes/immunology ; Macrophages/cytology ; Macrophages/immunology ; Male ; Middle Aged
Czasopismo naukowe

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