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    Wyświetlanie 1-18 z 18
    Tytuł:
    The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats.
    Autorzy:
    Lima-Garcia, JF
    Dutra, RC
    da Silva, KABS
    Motta, EM
    Campos, MM
    Calixto, JB
    Lima-Garcia, J F (AUTHOR)
    Dutra, R C (AUTHOR)
    Motta, E M (AUTHOR)
    Campos, M M (AUTHOR)
    Calixto, J B (AUTHOR)
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    Źródło:
    British Journal of Pharmacology. Sep2011, Vol. 164 Issue 2, p278-293. 16p.
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inhibitor of PI3Kγ ameliorates TNBS-induced colitis in mice by affecting the functional activity of CD4+CD25+FoxP3+ regulatory T cells.
    Autorzy:
    Dutra, RC
    Cola, M
    Leite, DFP
    Bento, AF
    Claudino, RF
    Nascimento, AFZ
    Leal, PC
    Calixto, JB
    Dutra, R C (AUTHOR)
    Leite, D F P (AUTHOR)
    Bento, A F (AUTHOR)
    Claudino, R F (AUTHOR)
    Nascimento, A F Z (AUTHOR)
    Leal, P C (AUTHOR)
    Calixto, J B (AUTHOR)
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    Źródło:
    British Journal of Pharmacology. May2011, Vol. 163 Issue 2, p358-374. 17p. 8 Graphs.
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Exacerbation of DSS-induced colitis in mice lacking kinin B1 receptors through compensatory up-regulation of kinin B2 receptors: the role of tight junctions and intestinal homeostasis.
    Autorzy:
    Marcon, R
    Claudino, RF
    Dutra, RC
    Bento, AF
    Schmidt, EC
    Bouzon, ZL
    Sordi, R
    Morais, RLT
    Pesquero, JB
    Calixto, JB
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    Temat:
    DISEASE exacerbation
    DEXTRAN sulfate
    COLITIS
    LABORATORY mice
    KININS
    TIGHT junctions
    HOMEOSTASIS
    INFLAMMATORY bowel diseases
    Źródło:
    British Journal of Pharmacology; Jan2013, Vol. 168 Issue 2, p389-402, 14p, 6 Graphs
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Health-related quality of life in children with cerebral palsy associated with congenital Zika infection.
    Autorzy:
    Marques FJP; Rede SARAH de Hospitais de Reabilitação, Rio de Janeiro, RJ, Brazil.
    Carvalho AL; Rede SARAH de Hospitais de Reabilitação, Salvador, BA, Brazil.
    Borigato EVM; Rede SARAH de Hospitais de Reabilitação, Brasília, DF, Brazil.
    Oliveira LFV; Rede SARAH de Hospitais de Reabilitação, Fortaleza, CE, Brazil.
    Duarte LMR; Rede SARAH de Hospitais de Reabilitação, Brasília, DF, Brazil.
    Silva AGD; Rede SARAH de Hospitais de Reabilitação, Brasília, DF, Brazil.
    Amarante CLD; Rede SARAH de Hospitais de Reabilitação, Rio de Janeiro, RJ, Brazil.
    Pereira LJM; Rede SARAH de Hospitais de Reabilitação, São Luis, MA, Brazil.
    Tavares EF; Rede SARAH de Hospitais de Reabilitação, Fortaleza, CE, Brazil.
    Costa LGSD; Rede SARAH de Hospitais de Reabilitação, São Luis, MA, Brazil.
    Alcântara CAR; Rede SARAH de Hospitais de Reabilitação, São Luis, MA, Brazil.
    Salinas AN; Rede SARAH de Hospitais de Reabilitação, São Luis, MA, Brazil.
    Pinto FLDC; Rede SARAH de Hospitais de Reabilitação, Belém, PA, Brazil.
    Alcântara GC; Rede SARAH de Hospitais de Reabilitação, Belém, PA, Brazil.
    Utsch F; Rede SARAH de Hospitais de Reabilitação, Belo Horizonte, MG, Brazil.
    Silva CRD; Rede SARAH de Hospitais de Reabilitação, Belo Horizonte, MG, Brazil.
    Reis DAD; Rede SARAH de Hospitais de Reabilitação, Macapá, AP, Brazil.
    Bessa WM; Rede SARAH de Hospitais de Reabilitação, Macapá, AP, Brazil.
    Dutra RC; Rede SARAH de Hospitais de Reabilitação, Macapá, AP, Brazil.
    Ventura P; Rede SARAH de Hospitais de Reabilitação, Salvador, BA, Brazil.
    Oliveira TS; Rede SARAH de Hospitais de Reabilitação, Salvador, BA, Brazil.
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    Źródło:
    Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo [Rev Paul Pediatr] 2023 Apr 07; Vol. 41, pp. e2022016. Date of Electronic Publication: 2023 Apr 07 (Print Publication: 2023).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Zika Virus Infection*/complications
    Zika Virus Infection*/epidemiology
    Cerebral Palsy*
    Communicable Diseases*
    Zika Virus*
    Humans ; Child ; Child, Preschool ; Quality of Life/psychology ; Activities of Daily Living/psychology ; Cross-Sectional Studies ; Surveys and Questionnaires ; Severity of Illness Index
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    β-caryophyllene, a cannabinoid receptor 2 agonist, decreases the motivational salience and conditioning place preference for palatable food in female mice.
    Autorzy:
    Dos Santos Barbosa LA; Programa de Pós-Graduação em Neurociências, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.
    Dutra RC; Programa de Pós-Graduação em Neurociências, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.; Laboratório de Autoimunidade e Imunofarmacologia (LAIF), Departamento de Ciências da Saúde, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá, Brazil.
    Moreira ELG; Programa de Pós-Graduação em Neurociências, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.; Departamento de Ciências Fisiológicas, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
    de Carvalho CR; Programa de Pós-Graduação em Neurociências, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.; Departamento de Patologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
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    Źródło:
    Addiction biology [Addict Biol] 2023 Jan; Vol. 28 (1), pp. e13249.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Sesquiterpenes*/pharmacology
    Mice ; Animals ; Cannabinoid Receptor Agonists/pharmacology ; Motivation ; Receptor, Cannabinoid, CB2 ; Receptor, Cannabinoid, CB1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Involvement of Opioid System and TRPM8/TRPA1 Channels in the Antinociceptive Effect of Spirulina platensis .
    Autorzy:
    Freitas MA; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Vasconcelos A; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Gonçalves ECD; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
    Ferrarini EG; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
    Vieira GB; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Cicia D; Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.
    Cola M; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Capasso R; Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy.; Endocannabinoid Research Group, 80078 Pozzuoli, Italy.
    Dutra RC; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
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    Źródło:
    Biomolecules [Biomolecules] 2021 Apr 17; Vol. 11 (4). Date of Electronic Publication: 2021 Apr 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Analgesics/*pharmacology
    Narcotic Antagonists/*pharmacology
    Nociceptive Pain/*drug therapy
    Plant Extracts/*pharmacology
    Spirulina/*chemistry
    TRPA1 Cation Channel/*metabolism
    TRPM Cation Channels/*metabolism
    Analgesics/therapeutic use ; Animals ; Capsaicin/pharmacology ; Male ; Mice ; Naloxone/pharmacology ; Nociception/drug effects ; Plant Extracts/therapeutic use
    SCR Organism:
    Arthrospira platensis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Antidepressant-Like Effect of Terpineol in an Inflammatory Model of Depression: Involvement of the Cannabinoid System and D2 Dopamine Receptor.
    Autorzy:
    Vieira G; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Cavalli J; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Gonçalves ECD; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
    Braga SFP; Laboratório de Modelagem Molecular e Planejamento de Fármacos, Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
    Ferreira RS; Laboratório de Modelagem Molecular e Planejamento de Fármacos, Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
    Santos ARS; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.; Laboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
    Cola M; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Raposo NRB; Center for Research and Innovation in Health Sciences (NUPICS), Faculty of Pharmacy, Universidade Federal de Juiz de Fora, Juiz de For a 36036-330, Brazil.
    Capasso R; Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy.; Endocannabinoid Research Group, 80078 Naples, Italy.
    Dutra RC; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Post-Graduate Program of Neuroscience, Center of Biological Science, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
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    Źródło:
    Biomolecules [Biomolecules] 2020 May 20; Vol. 10 (5). Date of Electronic Publication: 2020 May 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Anti-Inflammatory Agents/*therapeutic use
    Antidepressive Agents/*therapeutic use
    Cannabinoid Receptor Modulators/*therapeutic use
    Depression/*drug therapy
    Dopamine Agents/*therapeutic use
    Monoterpenes/*therapeutic use
    Animals ; Binding Sites ; Depression/etiology ; Hindlimb Suspension/adverse effects ; Lipopolysaccharides/toxicity ; Male ; Mice ; Molecular Docking Simulation ; Protein Binding ; Receptors, Cannabinoid/chemistry ; Receptors, Cannabinoid/metabolism ; Receptors, Dopamine D2/chemistry ; Receptors, Dopamine D2/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant.
    Autorzy:
    Gonçalves ECD; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Graduate Program of Neuroscience, Center of Biological Sciences, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
    Baldasso GM; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Bicca MA; Neurosurgery Department, Neurosurgery Pain Research institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
    Paes RS; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.
    Capasso R; Department of Agricultural Sciences, University of Naples Federico II, 80,055 Portici, Italy.
    Dutra RC; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Campus Araranguá, Universidade Federal de Santa Catarina, Araranguá 88906-072, Brazil.; Graduate Program of Neuroscience, Center of Biological Sciences, Campus Florianópolis, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Brazil.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2020 Mar 29; Vol. 25 (7). Date of Electronic Publication: 2020 Mar 29.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Alzheimer Disease/*drug therapy
    Anxiety/*drug therapy
    Cannabinoid Receptor Agonists/*chemistry
    Cannabis/*chemistry
    Cognitive Dysfunction/*drug therapy
    Neuroprotective Agents/*chemistry
    Schizophrenia/*drug therapy
    Alzheimer Disease/physiopathology ; Anxiety/physiopathology ; Bicyclic Monoterpenes/chemistry ; Bicyclic Monoterpenes/isolation & purification ; Bicyclic Monoterpenes/pharmacology ; Cannabidiol/chemistry ; Cannabidiol/isolation & purification ; Cannabidiol/pharmacology ; Cannabinoid Receptor Agonists/classification ; Cannabinoid Receptor Agonists/isolation & purification ; Cannabinoid Receptor Agonists/pharmacology ; Cognitive Dysfunction/physiopathology ; Dronabinol/chemistry ; Dronabinol/isolation & purification ; Dronabinol/pharmacology ; Humans ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/physiopathology ; Neuralgia/drug therapy ; Neuralgia/physiopathology ; Neuroprotective Agents/classification ; Neuroprotective Agents/isolation & purification ; Neuroprotective Agents/pharmacology ; Nootropic Agents/chemistry ; Nootropic Agents/classification ; Nootropic Agents/isolation & purification ; Nootropic Agents/pharmacology ; Schizophrenia/physiopathology ; Sesquiterpenes/chemistry ; Sesquiterpenes/isolation & purification ; Sesquiterpenes/pharmacology ; Terpenes/chemistry ; Terpenes/isolation & purification ; Terpenes/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Diacerein reduces joint damage, pain behavior and inhibits transient receptor potential vanilloid 1, matrix metalloproteinase and glial cells in rat spinal cord.
    Autorzy:
    da Silva MD; Laboratório de Neurobiologia da Dor e Inflamação, Departamento de Ciências Fisiológicas, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.; Programa de Pós-Graduação em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.; Departamento de Fisioterapia, Universidade Federal do Pampa, Uruguaiana, RS, Brazil.
    Cidral-Filho FJ; Laboratório de Neurobiologia da Dor e Inflamação, Departamento de Ciências Fisiológicas, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.; Programa de Pós-Graduação em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.
    Winkelmann-Duarte EC; Departamento de Ciências Morfológicas, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.
    Cargnin-Ferreira E; Laboratório de Marcadores Histológicos, Instituto Federal de Santa Catarina, Garopaba, SC, Brazil.
    Calixto JB; Centro de Inovação e Ensaios Pré-clínicos, Cachoeira do Bom Jesus, Florianópolis, SC, Brazil.; Departamento de Farmacologia, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.
    Dutra RC; Programa de Pós-Graduação em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.; Laboratório de Autoimunidade e Imunofarmacologia, Universidade Federal de Santa Catarina, Araranguá, SC, Brazil.
    Santos ARS; Laboratório de Neurobiologia da Dor e Inflamação, Departamento de Ciências Fisiológicas, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.; Programa de Pós-Graduação em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, Brazil.
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    Źródło:
    International journal of rheumatic diseases [Int J Rheum Dis] 2017 Oct; Vol. 20 (10), pp. 1337-1349. Date of Electronic Publication: 2015 Oct 20.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Analgesics/*pharmacology
    Anthraquinones/*pharmacology
    Antirheumatic Agents/*pharmacology
    Arthritis, Experimental/*prevention & control
    Behavior, Animal/*drug effects
    Joints/*drug effects
    Matrix Metalloproteinase 9/*metabolism
    Matrix Metalloproteinase Inhibitors/*pharmacology
    Neuroglia/*drug effects
    Spinal Cord/*drug effects
    TRPV Cation Channels/*antagonists & inhibitors
    Animals ; Arthritis, Experimental/enzymology ; Arthritis, Experimental/pathology ; Arthritis, Experimental/psychology ; Edema/enzymology ; Edema/pathology ; Edema/prevention & control ; Freund's Adjuvant ; Joints/pathology ; Male ; Neuroglia/enzymology ; Neuroglia/pathology ; Nociceptive Pain/chemically induced ; Nociceptive Pain/enzymology ; Nociceptive Pain/pathology ; Nociceptive Pain/psychology ; Rats, Wistar ; Spinal Cord/enzymology ; Spinal Cord/pathology ; Spinal Cord/physiopathology ; TRPV Cation Channels/metabolism ; Thermosensing/drug effects ; Time Factors ; Vocalization, Animal/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    (-)-β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis.
    Autorzy:
    Alberti TB; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Center of Araranguá, Federal University of Santa Catarina, Araranguá 88906-072, Brazil. .
    Barbosa WL; Faculty of Pharmaceutical Sciences, Federal University of Pará, Belém 66075-740, Brazil. .
    Vieira JL; Faculty of Pharmaceutical Sciences, Federal University of Pará, Belém 66075-740, Brazil. .
    Raposo NR; Research and Innovation in Health Sciences (NUPICS), Federal University of Juiz de Fora, Juiz de Fora 36036-900, Brazil. .
    Dutra RC; Laboratory of Autoimmunity and Immunopharmacology (LAIF), Department of Health Sciences, Center of Araranguá, Federal University of Santa Catarina, Araranguá 88906-072, Brazil. .
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2017 Apr 01; Vol. 18 (4). Date of Electronic Publication: 2017 Apr 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Encephalomyelitis, Autoimmune, Experimental/*prevention & control
    Neurogenic Inflammation/*prevention & control
    Paralysis/*prevention & control
    Receptor, Cannabinoid, CB2/*metabolism
    Sesquiterpenes/*pharmacology
    Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Cannabinoid Receptor Agonists/pharmacology ; Cytokines/metabolism ; Demyelinating Diseases/prevention & control ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/metabolism ; Encephalomyelitis, Autoimmune, Experimental/physiopathology ; Female ; Humans ; Hyperalgesia/prevention & control ; Mice, Inbred C57BL ; Microglia/drug effects ; Microglia/metabolism ; Multiple Sclerosis/metabolism ; Multiple Sclerosis/physiopathology ; Multiple Sclerosis/prevention & control ; Neurogenic Inflammation/metabolism ; Neurogenic Inflammation/physiopathology ; Paralysis/metabolism ; Paralysis/physiopathology ; Polycyclic Sesquiterpenes ; Receptor, Cannabinoid, CB2/agonists ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Th1 Cells/drug effects ; Th1 Cells/immunology ; Th1 Cells/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Low-level laser therapy ameliorates disease progression in a mouse model of multiple sclerosis.
    Autorzy:
    Gonçalves ED; a Laboratory of Autoimmunity and Immunopharmacology , Campus Araranguá, Universidade Federal de Santa Catarina , Araranguá , SC , Brazil .; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.
    Souza PS; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.
    Lieberknecht V; a Laboratory of Autoimmunity and Immunopharmacology , Campus Araranguá, Universidade Federal de Santa Catarina , Araranguá , SC , Brazil .
    Fidelis GS; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.
    Barbosa RI; c Laboratory of Assessment and Rehabilitation of Locomotor System , Campus Araranguá, Universidade Federal de Santa Catarina , Araranguá , SC , Brazil.
    Silveira PC; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.
    de Pinho RA; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.
    Dutra RC; a Laboratory of Autoimmunity and Immunopharmacology , Campus Araranguá, Universidade Federal de Santa Catarina , Araranguá , SC , Brazil .; b Laboratory of Exercise Biochemistry and Physiology , Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense , Criciúma , SC , Brazil , and.; c Laboratory of Assessment and Rehabilitation of Locomotor System , Campus Araranguá, Universidade Federal de Santa Catarina , Araranguá , SC , Brazil.
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    Źródło:
    Autoimmunity [Autoimmunity] 2016; Vol. 49 (2), pp. 132-42. Date of Electronic Publication: 2015 Dec 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Low-Level Light Therapy*
    Multiple Sclerosis/*pathology
    Animals ; Antioxidants/metabolism ; Central Nervous System/immunology ; Central Nervous System/metabolism ; Central Nervous System/pathology ; Cytokines/metabolism ; Demyelinating Diseases/immunology ; Demyelinating Diseases/pathology ; Demyelinating Diseases/therapy ; Disease Models, Animal ; Disease Progression ; Encephalomyelitis, Autoimmune, Experimental ; Female ; Inflammation Mediators/metabolism ; Lipid Peroxidation ; Lymphoid Tissue/immunology ; Lymphoid Tissue/metabolism ; Mice ; Multiple Sclerosis/immunology ; Multiple Sclerosis/metabolism ; Multiple Sclerosis/therapy ; Nitric Oxide/metabolism ; Oxidation-Reduction ; Oxidative Stress
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The role of kinin receptors in preventing neuroinflammation and its clinical severity during experimental autoimmune encephalomyelitis in mice.
    Autorzy:
    Dutra RC; Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.
    Leite DF
    Bento AF
    Manjavachi MN
    Patrício ES
    Figueiredo CP
    Pesquero JB
    Calixto JB
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    Źródło:
    PloS one [PLoS One] 2011; Vol. 6 (11), pp. e27875. Date of Electronic Publication: 2011 Nov 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Encephalomyelitis, Autoimmune, Experimental/*complications
    Encephalomyelitis, Autoimmune, Experimental/*pathology
    Inflammation/*pathology
    Inflammation/*prevention & control
    Receptors, Bradykinin/*metabolism
    Spinal Cord/*pathology
    Animals ; Bradykinin Receptor Antagonists ; CD4-Positive T-Lymphocytes/immunology ; Chronic Disease ; Cytokines/biosynthesis ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Gene Deletion ; Humans ; Inflammation/complications ; Lymphoid Tissue/immunology ; Lymphoid Tissue/pathology ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Myelin Sheath/metabolism ; Spinal Cord/metabolism ; Th1 Cells/immunology ; Th17 Cells/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.
    Autorzy:
    Dutra RC; Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
    Claudino RF
    Bento AF
    Marcon R
    Schmidt EC
    Bouzon ZL
    Pianowski LF
    Calixto JB
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    Źródło:
    PloS one [PLoS One] 2011; Vol. 6 (11), pp. e27122. Date of Electronic Publication: 2011 Nov 02.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Colitis/*drug therapy
    Lanosterol/*analogs & derivatives
    Animals ; Colitis/metabolism ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay ; Lanosterol/pharmacology ; Lanosterol/therapeutic use ; Macrophages/drug effects ; Macrophages/metabolism ; Mice ; NF-kappa B/metabolism ; Real-Time Polymerase Chain Reaction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases.
    Autorzy:
    Paszcuk AF; Department of Pharmacology, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.
    Dutra RC
    da Silva KA
    Quintão NL
    Campos MM
    Calixto JB
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2011; Vol. 6 (9), pp. e24034. Date of Electronic Publication: 2011 Sep 13.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Analgesics/*pharmacology
    Brachial Plexus/*injuries
    Cannabinoids/*pharmacology
    Mitogen-Activated Protein Kinases/*metabolism
    Neuralgia/*enzymology
    Neuralgia/*pathology
    Neuroglia/*drug effects
    Animals ; Behavior, Animal/drug effects ; Benzoxazines/pharmacology ; Cyclic AMP Response Element-Binding Protein/metabolism ; Enzyme Activation/drug effects ; Female ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Ganglia, Spinal/pathology ; Gene Knockdown Techniques ; Hyperalgesia/complications ; Mice ; Morpholines/pharmacology ; NF-kappa B/metabolism ; Naphthalenes/pharmacology ; Neuralgia/etiology ; Neuralgia/metabolism ; Neuroglia/metabolism ; Neuroglia/pathology ; Nociception/drug effects ; Receptor, Cannabinoid, CB1/agonists ; Receptor, Cannabinoid, CB1/antagonists & inhibitors ; Receptor, Cannabinoid, CB1/deficiency ; Receptor, Cannabinoid, CB1/genetics ; Receptor, Cannabinoid, CB2/agonists ; Receptor, Cannabinoid, CB2/antagonists & inhibitors ; Receptor, Cannabinoid, CB2/deficiency ; Receptor, Cannabinoid, CB2/genetics ; Signal Transduction/drug effects ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Spinal Cord/pathology ; Up-Regulation/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Antioxidant and cytotoxic activities of Centella asiatica (L) Urb.
    Autorzy:
    Pittella F; Departamento de Alimentos e Toxicologia, Faculdade de Farmácia e Bioquímica, Universidade Federal de Juiz de Fora, Martelos, CEP 36036-330, Juiz de Fora, MG, Brazil.
    Dutra RC; Departamento de Alimentos e Toxicologia, Faculdade de Farmácia e Bioquímica, Universidade Federal de Juiz de Fora, Martelos, CEP 36036-330, Juiz de Fora, MG, Brazil.
    Junior DD; Laboratório de Substâncias Antitumorais, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, CEP 31270-901, Belo Horizonte, MG, Brazil.
    Lopes MTP; Laboratório de Substâncias Antitumorais, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, CEP 31270-901, Belo Horizonte, MG, Brazil.
    Barbosa NR; Departamento de Alimentos e Toxicologia, Faculdade de Farmácia e Bioquímica, Universidade Federal de Juiz de Fora, Martelos, CEP 36036-330, Juiz de Fora, MG, Brazil.
    Pokaż więcej
    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2009 Aug 26; Vol. 10 (9), pp. 3713-3721. Date of Electronic Publication: 2009 Aug 26.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents, Phytogenic/*pharmacology
    Centella/*chemistry
    Free Radical Scavengers/*pharmacology
    Plant Extracts/*pharmacology
    Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Biphenyl Compounds/chemistry ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Free Radical Scavengers/chemistry ; Free Radicals/chemistry ; Humans ; Inhibitory Concentration 50 ; Mice ; Phenols/chemistry ; Phenols/pharmacology ; Picrates/chemistry ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Rats
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-18 z 18

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