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Wyszukujesz frazę ""E2F Transcription Factors"" wg kryterium: Temat


Tytuł :
Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B.
Autorzy :
Roelofs PA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Goh CY; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Chua BH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Jarvis MC; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.
Stewart TA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Mater Research Institute, The University of Queensland, Faculty of Medicine, Brisbane, Australia.
McCann JL; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
McDougle RM; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Hennepin Healthcare, Minneapolis, United States.
Carpenter MA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
Martens JW; Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands.
Span PN; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Kappei D; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Harris RS; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
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Źródło :
ELife [Elife] 2020 Sep 28; Vol. 9. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Cytidine Deaminase/*genetics
E2F Transcription Factors/*genetics
Minor Histocompatibility Antigens/*genetics
Cytidine Deaminase/metabolism ; E2F Transcription Factors/metabolism ; HEK293 Cells ; Humans ; MCF-7 Cells ; Minor Histocompatibility Antigens/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł :
The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2- Breast Cancer.
Autorzy :
Oshi M; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Takahashi H; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Tokumaru Y; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Surgical Oncology, Graduate School of Medicine, Gifu University, Gifu 501-1194, Japan.
Yan L; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Rashid OM; Department of Surgery, Holy Cross Hospital, Michael and Dianne Bienes Comprehensive Cancer Center, Fort Lauderdale, FL 33308, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Nagahashi M; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 9518520, Japan.
Matsuyama R; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Endo I; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Takabe K; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima 9601295, Japan.; Department of Surgery, Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, NY 14263, USA.; Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 9518510, Japan.; Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo 1608402, Japan.
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Źródło :
Cells [Cells] 2020 Jul 08; Vol. 9 (7). Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
E2F Transcription Factors/*metabolism
Receptor, ErbB-2/*metabolism
Receptors, Estrogen/*metabolism
Biomarkers, Tumor/genetics ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Disease-Free Survival ; E2F Transcription Factors/genetics ; Female ; Humans ; Receptor, ErbB-2/genetics ; Receptors, Estrogen/genetics
Czasopismo naukowe
Tytuł :
Upregulation of PACE4 in prostate cancer is not dependent on E2F transcription factors.
Autorzy :
Bakrania A; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Aubé M; Department of Surgery, Division of Urology, McGill University, Montréal, QC H3A 0G4, Canada.
Desjardins R; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Sabbagh R; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Day R; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
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Źródło :
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Jul; Vol. 98 (7), pp. 477-481. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*genetics
E2F Transcription Factors/*metabolism
Proprotein Convertases/*genetics
Prostatic Neoplasms/*genetics
Serine Endopeptidases/*genetics
Adenocarcinoma/pathology ; Cell Line, Tumor ; Datasets as Topic ; E2F Transcription Factors/genetics ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Male ; Prostatic Neoplasms/pathology ; Protein Isoforms/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
CDK4/RB/E2Fs axis as potential therapeutic target of endometrial cancer.
Autorzy :
Hu J; Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China.
Shen J; Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. Electronic address: .
Sun J; Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2020 May; Vol. 125, pp. 109870. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
Cyclin-Dependent Kinase 4/*metabolism
E2F Transcription Factors/*metabolism
Endometrial Neoplasms/*etiology
Endometrial Neoplasms/*metabolism
Retinoblastoma Protein/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Cyclin-Dependent Kinase 4/genetics ; DNA Copy Number Variations ; Disease Models, Animal ; E2F Transcription Factors/genetics ; Endometrial Neoplasms/drug therapy ; Endometrial Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mice ; Molecular Targeted Therapy ; Mutation ; Prognosis ; Protein Binding ; Retinoblastoma Protein/genetics ; Signal Transduction/drug effects ; Transcriptional Activation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Identification of E2F transcription factor 7 as a novel potential biomarker for oral squamous cell carcinoma.
Autorzy :
Zhou P; Department of Stomatology, Jining No.1 People's Hospital, Jining, 272000, Shandong, China.
Xiao L; Department of Stomatology, Yantai Yuhuangding Hospital, Yantai, 264000, Shandong, China.
Xu X; Department of Stomatology, Jining No.1 People's Hospital, Jining, 272000, Shandong, China. .
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Źródło :
Head & face medicine [Head Face Med] 2021 Feb 26; Vol. 17 (1), pp. 7. Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Squamous Cell*/genetics
Head and Neck Neoplasms*
Mouth Neoplasms*/genetics
Cell Line, Tumor ; Cell Proliferation ; E2F Transcription Factors ; Humans ; Squamous Cell Carcinoma of Head and Neck/genetics
Czasopismo naukowe
Tytuł :
A masked initiation region in retinoblastoma protein regulates its proteasomal degradation.
Autorzy :
Tomita T; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA.
Huibregtse JM; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA.
Matouschek A; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, 78712, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Apr 24; Vol. 11 (1), pp. 2019. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Calpain/*metabolism
E2F Transcription Factors/*genetics
Papillomavirus E7 Proteins/*metabolism
Retinoblastoma Binding Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Uterine Cervical Neoplasms/*genetics
Acrylates/pharmacology ; Calpain/antagonists & inhibitors ; Cell Cycle/genetics ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/pathology ; Cyclopentanes/pharmacology ; E2F Transcription Factors/metabolism ; Female ; HEK293 Cells ; Human papillomavirus 16/metabolism ; Human papillomavirus 16/pathogenicity ; Humans ; NEDD8 Protein/antagonists & inhibitors ; NEDD8 Protein/metabolism ; Oligopeptides/pharmacology ; Proteasome Endopeptidase Complex/drug effects ; Proteasome Endopeptidase Complex/metabolism ; Protein Stability/drug effects ; Pyrimidines/pharmacology ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Retinoblastoma Binding Proteins/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination/drug effects ; Ubiquitination/genetics ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/virology
Czasopismo naukowe
Tytuł :
Prx II reduces oxidative stress and cell senescence in chondrocytes by activating the p16-CDK4/6-pRb-E2F signaling pathway.
Autorzy :
Shao JH; Department of Joint Surgery and Orthopedic Medicine, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China. .
Fu QW
Li LX
Zhou R
Liu N
Peng JH
Chen Y
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Źródło :
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2020 Apr; Vol. 24 (7), pp. 3448-3458.
Typ publikacji :
Journal Article
MeSH Terms :
Cellular Senescence*
Oxidative Stress*
Chondrocytes/*metabolism
Cyclin-Dependent Kinase 4/*metabolism
Cyclin-Dependent Kinase Inhibitor p16/*metabolism
E2F Transcription Factors/*metabolism
Osteoarthritis/*metabolism
Peroxiredoxins/*metabolism
Cells, Cultured ; Cyclin-Dependent Kinase 4/genetics ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; E2F Transcription Factors/genetics ; Humans ; Signal Transduction
Czasopismo naukowe
Tytuł :
Integrated analysis of the E2F transcription factors across cancer types.
Autorzy :
Wang H; Fujian Provincial Prenatal Diagnosis Center, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Wang X; Fujian Provincial Prenatal Diagnosis Center, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Xu L; Fujian Provincial Prenatal Diagnosis Center, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Zhang J; State Key Laboratory for Medical Genomics, Shanghai Institute of Hematology, Rui‑Jin Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, P.R. China.
Cao H; Fujian Provincial Prenatal Diagnosis Center, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
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Źródło :
Oncology reports [Oncol Rep] 2020 Apr; Vol. 43 (4), pp. 1133-1146. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
E2F Transcription Factors/*metabolism
Neoplasms/*pathology
Biomarkers, Tumor/genetics ; Computational Biology/methods ; DNA Methylation ; Databases, Genetic ; E2F Transcription Factors/genetics ; Gene Amplification ; Gene Expression Profiling/methods ; Humans ; Neoplasms/genetics ; Neoplasms/metabolism ; Prognosis ; Survival Rate ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Cryptochromes modulate E2F family transcription factors.
Autorzy :
Chan AB; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Huber AL; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.; Centre de Recherche en Cancerologie de Lyon, 28 rue Laennec, 69008, Lyon, France.
Lamia KA; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 05; Vol. 10 (1), pp. 4077. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Circadian Rhythm*
Gene Expression Regulation*
Cryptochromes/*physiology
E2F Transcription Factors/*metabolism
Transcription Factors/*metabolism
Ubiquitin-Protein Ligase Complexes/*metabolism
Animals ; E2F Transcription Factors/genetics ; Mice, Knockout ; Transcription Factors/genetics ; Ubiquitin-Protein Ligase Complexes/genetics
Czasopismo naukowe
Tytuł :
CKAP2L Knockdown Exerts Antitumor Effects by Increasing miR-4496 in Glioblastoma Cell Lines.
Autorzy :
Li YF; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Tsai WC; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Chou CH; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
Huang LC; Department of Biochemistry, National Defense Medical Center, Taipei 11490, Taiwan.
Huang SM; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.; Department of Biochemistry, National Defense Medical Center, Taipei 11490, Taiwan.
Hueng DY; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan.; Department of Biochemistry, National Defense Medical Center, Taipei 11490, Taiwan.; Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Tsai CK; Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 27; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 27.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms/*metabolism
Cell Proliferation/*genetics
Cytoskeletal Proteins/*metabolism
Epithelial-Mesenchymal Transition/*genetics
G2 Phase Cell Cycle Checkpoints/*genetics
Gene Expression Regulation, Neoplastic/*genetics
Glioblastoma/*metabolism
MicroRNAs/*metabolism
Brain Neoplasms/genetics ; Brain Neoplasms/mortality ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Central Nervous System Neoplasms/genetics ; Central Nervous System Neoplasms/metabolism ; Central Nervous System Neoplasms/mortality ; Central Nervous System Neoplasms/pathology ; Cytoskeletal Proteins/genetics ; Databases, Genetic ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Female ; Gene Knockdown Techniques ; Glioblastoma/genetics ; Glioma/genetics ; Glioma/metabolism ; Glioma/mortality ; Glioma/pathology ; Humans ; Immunohistochemistry ; Male ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness/genetics ; Prognosis ; Tissue Array Analysis
Czasopismo naukowe
Tytuł :
E2FB Interacts with RETINOBLASTOMA RELATED and Regulates Cell Proliferation during Leaf Development.
Autorzy :
Őszi E; Institute of Plant Biology, Biological Research Centre, Szeged, 6726, Hungary.; Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged, 6726, Hungary.
Papdi C; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Mohammed B; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Petkó-Szandtner A; Institute of Plant Biology, Biological Research Centre, Szeged, 6726, Hungary.; Institute of Biochemistry, Biological Research Centre, Szeged, 6726, Hungary.
Leviczky T; Institute of Plant Biology, Biological Research Centre, Szeged, 6726, Hungary.; Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged, 6726, Hungary.
Molnár E; Institute of Plant Biology, Biological Research Centre, Szeged, 6726, Hungary.
Galvan-Ampudia C; Laboratoire de Reproduction et Développement des Plantes, Université de Lyon, Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, F-69364 Lyon, France.
Khan S; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Juez EL; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Horváth B; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Bögre L; Royal Holloway University of London, School of Biological Sciences, Centre for Systems and Synthetic Biology, Egham, TW20 0EX, United Kingdom.
Magyar Z; Institute of Plant Biology, Biological Research Centre, Szeged, 6726, Hungary .
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Źródło :
Plant physiology [Plant Physiol] 2020 Jan; Vol. 182 (1), pp. 518-533. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Arabidopsis/*metabolism
Arabidopsis Proteins/*metabolism
E2F Transcription Factors/*metabolism
Plant Leaves/*metabolism
Plants, Genetically Modified/*metabolism
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; E2F Transcription Factors/genetics ; Gene Expression Regulation, Plant/genetics ; Mutation/genetics ; Plant Leaves/genetics ; Plants, Genetically Modified/genetics ; Promoter Regions, Genetic/genetics
Czasopismo naukowe
Tytuł :
Transient overexpression of E2Fb triggers cell divisions in pavement cells of Nicotiana benthamiana leaves.
Autorzy :
Jiménez-Gόngora T; Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 201602, China.; University of the Chinese Academy of Sciences, Beijing, 100049, China.
Tan H; Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 201602, China.; University of the Chinese Academy of Sciences, Beijing, 100049, China.
Lozano-Durán R; Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, 201602, China. .
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Źródło :
Plant cell reports [Plant Cell Rep] 2019 Dec; Vol. 38 (12), pp. 1465-1471. Date of Electronic Publication: 2019 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
E2F Transcription Factors/*metabolism
Plant Leaves/*metabolism
Plants, Genetically Modified/*metabolism
Tobacco/*metabolism
Cell Division/genetics ; Cell Division/physiology ; DNA Replication/genetics ; DNA Replication/physiology ; E2F Transcription Factors/genetics ; Plant Leaves/genetics ; Plants, Genetically Modified/genetics ; Tobacco/genetics
Czasopismo naukowe
Tytuł :
Regulation of the transcription factor E2F8 gene expression in bovine ovarian cells.
Autorzy :
Morrell BC; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
Zhang L; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
Schütz LF; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
Perego MC; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
Maylem ERS; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA.
Spicer LJ; Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK, 74078, USA. Electronic address: .
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Źródło :
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2019 Dec 01; Vol. 498, pp. 110572. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
E2F Transcription Factors/*metabolism
Fibroblast Growth Factor 9/*metabolism
Granulosa Cells/*metabolism
Ovarian Follicle/*metabolism
RNA, Messenger/*metabolism
Theca Cells/*metabolism
Animals ; Cattle ; E2F Transcription Factors/genetics ; Female ; Fibroblast Growth Factor 9/genetics ; Granulosa Cells/cytology ; Ovarian Follicle/cytology ; RNA, Messenger/genetics ; Theca Cells/cytology
Czasopismo naukowe
Tytuł :
mRNA and miRNA Expression Analyses of the MYC / E2F /miR-17-92 Network in the Most Common Pediatric Brain Tumors.
Autorzy :
Gruszka R; Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-216 Lodz, Poland.; Biobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 139, 90-235 Lodz, Poland.
Zakrzewski K; Department of Neurosurgery, Polish Mother Memorial Hospital Research Institute in Lodz, Rzgowska 281/289, 93-338 Lodz, Poland.
Liberski PP; Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-216 Lodz, Poland.
Zakrzewska M; Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-216 Lodz, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 07; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytoma/*genetics
Brain Neoplasms/*genetics
E2F Transcription Factors/*genetics
MicroRNAs/*genetics
Proto-Oncogene Proteins c-myc/*genetics
Astrocytoma/pathology ; Brain Neoplasms/pathology ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Gene Regulatory Networks/genetics ; Humans ; Pediatrics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.
Autorzy :
Hoj JP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710.
Mayro B; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710.
Pendergast AM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 29; Vol. 117 (52), pp. 33486-33495. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription, Genetic*
Adenocarcinoma of Lung/*genetics
Adenocarcinoma of Lung/*pathology
Brain Neoplasms/*secondary
Heat Shock Transcription Factors/*metabolism
Lung Neoplasms/*genetics
Lung Neoplasms/*pathology
Protein-Tyrosine Kinases/*metabolism
Allosteric Regulation ; Animals ; Cell Line, Tumor ; Cell Survival ; E2F Transcription Factors/metabolism ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Mice, Nude ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Bistable switches as integrators and actuators during cell cycle progression.
Autorzy :
Stallaert W; Department of Genetics, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Kedziora KM; Department of Genetics, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Chao HX; Department of Genetics, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Purvis JE; Department of Genetics, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
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Źródło :
FEBS letters [FEBS Lett] 2019 Oct; Vol. 593 (20), pp. 2805-2816. Date of Electronic Publication: 2019 Oct 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
DNA Repair*/drug effects
Cell Cycle/*genetics
Cell Cycle Checkpoints/*genetics
Cyclin-Dependent Kinases/*genetics
E2F Transcription Factors/*genetics
Retinoblastoma Protein/*genetics
Animals ; Cell Cycle/drug effects ; Cell Cycle Checkpoints/drug effects ; Cyclin-Dependent Kinases/metabolism ; DNA Damage/drug effects ; DNA Replication/drug effects ; E2F Transcription Factors/metabolism ; Eukaryotic Cells/cytology ; Eukaryotic Cells/drug effects ; Eukaryotic Cells/metabolism ; Gene Expression Regulation ; Humans ; Intercellular Signaling Peptides and Proteins/pharmacology ; Mitogens/pharmacology ; Retinoblastoma Protein/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Overexpression and alternative splicing of NF-YA in breast cancer.
Autorzy :
Dolfini D; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.
Andrioletti V; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.; Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Germany.
Mantovani R; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy. .
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Źródło :
Scientific reports [Sci Rep] 2019 Sep 10; Vol. 9 (1), pp. 12955. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
BRCA1 Protein/*metabolism
BRCA2 Protein/*metabolism
Biomarkers, Tumor/*genetics
Breast Neoplasms/*pathology
CCAAT-Binding Factor/*genetics
E2F Transcription Factors/*metabolism
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; CCAAT-Binding Factor/metabolism ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; E2F Transcription Factors/genetics ; Female ; Gene Expression Profiling ; Humans ; Promoter Regions, Genetic ; Protein Binding ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer.
Autorzy :
Dahl ES; Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania.
Buj R; Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania.
Leon KE; Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania.
Newell JM; Department of Pathology, Penn State College of Medicine, Hershey, Pennsylvania.
Imamura Y; Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania.
Bitler BG; Division of Reproductive Sciences, University of Colorado Anschutz Medical Campus, Denver, Colorado.
Snyder NW; AJ Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania.
Aird KM; Department of Cellular & Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania. .
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Źródło :
Molecular cancer research : MCR [Mol Cancer Res] 2019 Aug; Vol. 17 (8), pp. 1710-1720. Date of Electronic Publication: 2019 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cellular Senescence*
Gene Expression Regulation, Neoplastic*
Carcinoma, Ovarian Epithelial/*pathology
Cystadenocarcinoma, Serous/*pathology
E2F Transcription Factors/*metabolism
Histones/*metabolism
Isocitrate Dehydrogenase/*metabolism
Apoptosis ; Carcinoma, Ovarian Epithelial/genetics ; Carcinoma, Ovarian Epithelial/metabolism ; Cell Proliferation ; Cystadenocarcinoma, Serous/genetics ; Cystadenocarcinoma, Serous/metabolism ; E2F Transcription Factors/genetics ; Epigenesis, Genetic ; Female ; Histones/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Neoplasm Grading ; Survival Rate ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation.
Autorzy :
Lim N; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Manchester Cancer Research Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, United Kingdom.
Townsend PA; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Manchester Cancer Research Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, United Kingdom.; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
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Źródło :
International journal of cancer [Int J Cancer] 2020 Sep 15; Vol. 147 (6), pp. 1528-1534. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carcinogenesis/*genetics
Cell Cycle Proteins/*metabolism
Gene Expression Regulation, Neoplastic/*drug effects
Nuclear Proteins/*metabolism
Pancreatic Neoplasms/*genetics
Antineoplastic Agents/therapeutic use ; Carcinogenesis/drug effects ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Cycle Proteins/antagonists & inhibitors ; Cell Cycle Proteins/genetics ; Cell Nucleus/metabolism ; Cellular Senescence/drug effects ; Cellular Senescence/genetics ; Cyclin E/metabolism ; Cytoplasm/metabolism ; DNA Damage/drug effects ; DNA Damage/genetics ; DNA Replication ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Epithelial-Mesenchymal Transition/drug effects ; Epithelial-Mesenchymal Transition/genetics ; Gene Amplification ; Humans ; Mutation ; Nuclear Proteins/antagonists & inhibitors ; Nuclear Proteins/genetics ; Oncogene Proteins/metabolism ; Pancreas/drug effects ; Pancreas/pathology ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/pathology ; Proto-Oncogene Proteins p21(ras)/genetics
Czasopismo naukowe
Tytuł :
The broken cycle: E2F dysfunction in cancer.
Autorzy :
Kent LN; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Leone G; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA. .
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2019 Jun; Vol. 19 (6), pp. 326-338.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
E2F Transcription Factors/*metabolism
Neoplasms/*drug therapy
Neoplasms/*pathology
Animals ; Apoptosis/physiology ; Cell Proliferation ; Chromosomal Instability ; DNA Damage/physiology ; E2F Transcription Factors/genetics ; Humans ; Molecular Targeted Therapy/methods ; Multigene Family ; Neoplasms/genetics ; Protein Processing, Post-Translational ; Protein Stability
Czasopismo naukowe

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