Temat: "E2F Transcription Factors" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Cell cycle regulation of the psoriasis associated gene CCHCR1 by transcription factor E2F1.
Autorzy:: Ling YH; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Chen Y; School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Leung KN; School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Chan KM; School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Liu WK; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Dec 21; Vol. 18 (12), pp. e0294661. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: E2F1 Transcription Factor*/genetics
E2F1 Transcription Factor*/metabolism
Psoriasis*/genetics
Psoriasis*/metabolism
Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Gene Expression Regulation ; Cell Cycle ; E2F Transcription Factors/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism

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Skocz do pozycji: 2.

Tytuł:: Function and Characteristic Analysis of Candidate PEAR Proteins in Populus yunnanensis .
Autorzy:: Li P; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.
Wang J; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.
Jiang D; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.
Yu A; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.
Sun R; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.
Liu A; Key Laboratory for Forest Resource Conservation and Utilization in the Southwest Mountains of China (Ministry of Education), College of Forestry, Southwest Forestry University, Kunming 650224, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Aug 23; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Populus*/genetics
Arabidopsis*
Phylogeny ; Cambium ; Cell Cycle ; DNA, Plant ; E2F Transcription Factors

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Skocz do pozycji: 3.

Tytuł:: E2F transcription factor 1 elevates cyclin D1 expression by suppressing transcription of microRNA-107 to augment progression of glioma.
Autorzy:: Xie H; Department of Clinical Medicine, Jiangxi Health Vocational College, Nanchang, P. R. China.
Lv S; Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, P. R. China.
Wang Z; Department of Clinical Medicine, Jiangxi Health Vocational College, Nanchang, P. R. China.
Yuan X; Department of Clinical Medicine, Jiangxi Health Vocational College, Nanchang, P. R. China.; Pokaż więcej
Źródło:: Brain and behavior [Brain Behav] 2021 Dec; Vol. 11 (12), pp. e2399. Date of Electronic Publication: 2021 Nov 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cyclin D1*/genetics
Cyclin D1*/metabolism
E2F Transcription Factors*/metabolism
Glioma*/genetics
Glioma*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation/genetics ; Humans ; Mice ; Mice, Nude

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Skocz do pozycji: 4.

Tytuł:: PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genes.
Autorzy:: Doi K; Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Japan.
Takeuchi H; Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Japan.
Sakurai H; Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Japan.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2023 Feb; Vol. 290 (3), pp. 745-762. Date of Electronic Publication: 2022 Sep 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Retinoblastoma Protein*/genetics
Retinoblastoma Protein*/metabolism
Immediate-Early Proteins*/metabolism
Protein Phosphatase 2/genetics ; Protein Phosphatase 2/metabolism ; Retinoblastoma-Like Protein p107/genetics ; Retinoblastoma-Like Protein p107/metabolism ; Protein Processing, Post-Translational ; Phosphorylation ; Cell Cycle/genetics ; E2F Transcription Factors/metabolism

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Skocz do pozycji: 5.

Tytuł:: The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2- Breast Cancer.
Autorzy:: Oshi M; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Takahashi H; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Tokumaru Y; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Surgical Oncology, Graduate School of Medicine, Gifu University, Gifu 501-1194, Japan.
Yan L; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Rashid OM; Department of Surgery, Holy Cross Hospital, Michael and Dianne Bienes Comprehensive Cancer Center, Fort Lauderdale, FL 33308, USA.; Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Nagahashi M; Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 9518520, Japan.
Matsuyama R; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Endo I; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.
Takabe K; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama 2360004, Japan.; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima 9601295, Japan.; Department of Surgery, Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, NY 14263, USA.; Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 9518510, Japan.; Department of Breast Surgery and Oncology, Tokyo Medical University, Tokyo 1608402, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Jul 08; Vol. 9 (7). Date of Electronic Publication: 2020 Jul 08.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers, Tumor/*metabolism
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
E2F Transcription Factors/*metabolism
Receptor, ErbB-2/*metabolism
Receptors, Estrogen/*metabolism
Biomarkers, Tumor/genetics ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Disease-Free Survival ; E2F Transcription Factors/genetics ; Female ; Humans ; Receptor, ErbB-2/genetics ; Receptors, Estrogen/genetics

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Skocz do pozycji: 6.

Tytuł:: Expression and prognostic role of E2F transcription factors in high-grade glioma.
Autorzy:: Yu H; Department of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Li Z; Department of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang M; Department of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2020 Jul; Vol. 26 (7), pp. 741-753. Date of Electronic Publication: 2020 Feb 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Brain Neoplasms/*metabolism
E2F Transcription Factors/*biosynthesis
Glioma/*metabolism
Adult ; Animals ; Brain Neoplasms/diagnosis ; Brain Neoplasms/genetics ; Cell Line, Tumor ; E2F Transcription Factors/genetics ; Female ; Glioma/diagnosis ; Glioma/genetics ; HEK293 Cells ; Humans ; Male ; Mice, Nude ; Middle Aged ; Neoplasm Grading/methods ; Prognosis ; Xenograft Model Antitumor Assays/methods

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Skocz do pozycji: 7.

Tytuł:: Upregulation of PACE4 in prostate cancer is not dependent on E2F transcription factors.
Autorzy:: Bakrania A; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Aubé M; Department of Surgery, Division of Urology, McGill University, Montréal, QC H3A 0G4, Canada.
Desjardins R; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Sabbagh R; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
Day R; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Department of Surgery, Division of Urology, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Jul; Vol. 98 (7), pp. 477-481. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Adenocarcinoma/*genetics
E2F Transcription Factors/*metabolism
Proprotein Convertases/*genetics
Prostatic Neoplasms/*genetics
Serine Endopeptidases/*genetics
Adenocarcinoma/pathology ; Cell Line, Tumor ; Datasets as Topic ; E2F Transcription Factors/genetics ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Male ; Prostatic Neoplasms/pathology ; Protein Isoforms/genetics ; Up-Regulation

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Skocz do pozycji: 8.

Tytuł:: Cryptochromes modulate E2F family transcription factors.
Autorzy:: Chan AB; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Huber AL; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.; Centre de Recherche en Cancerologie de Lyon, 28 rue Laennec, 69008, Lyon, France.
Lamia KA; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Mar 05; Vol. 10 (1), pp. 4077. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Circadian Rhythm*
Gene Expression Regulation*
Cryptochromes/*physiology
E2F Transcription Factors/*metabolism
Transcription Factors/*metabolism
Ubiquitin-Protein Ligase Complexes/*metabolism
Animals ; E2F Transcription Factors/genetics ; Mice, Knockout ; Transcription Factors/genetics ; Ubiquitin-Protein Ligase Complexes/genetics

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Skocz do pozycji: 9.

Tytuł:: Overexpression and alternative splicing of NF-YA in breast cancer.
Autorzy:: Dolfini D; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.
Andrioletti V; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.; Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Germany.
Mantovani R; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Sep 10; Vol. 9 (1), pp. 12955. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alternative Splicing*
BRCA1 Protein/*metabolism
BRCA2 Protein/*metabolism
Biomarkers, Tumor/*genetics
Breast Neoplasms/*pathology
CCAAT-Binding Factor/*genetics
E2F Transcription Factors/*metabolism
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; CCAAT-Binding Factor/metabolism ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; E2F Transcription Factors/genetics ; Female ; Gene Expression Profiling ; Humans ; Promoter Regions, Genetic ; Protein Binding ; Tumor Cells, Cultured

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Skocz do pozycji: 10.

Tytuł:: Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis.
Autorzy:: Ye Q; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Taleb SJ; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Wang H; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Parinandi NL; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Kass DJ; Department of Medicine, The University of Pittsburgh, Pittsburgh, PA 15213, USA.
Rojas M; Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.
Wang C; Department of Bioinformatics, The Ohio State University, Columbus, OH 43210, USA.
Ma Q; Department of Bioinformatics, The Ohio State University, Columbus, OH 43210, USA.
Zhao J; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.; Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.
Zhao Y; Department of Physiology and Cell Biology, Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.; Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Oct 21; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Idiopathic Pulmonary Fibrosis*/chemically induced
Idiopathic Pulmonary Fibrosis*/genetics
Idiopathic Pulmonary Fibrosis*/metabolism
Animals ; Humans ; Mice ; Bleomycin/adverse effects ; E2F Transcription Factors/metabolism ; Fibroblasts/metabolism ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Hemin/pharmacology ; Hemin/metabolism ; Lung/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Serine/metabolism ; Transforming Growth Factor beta1/metabolism

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Skocz do pozycji: 11.

Tytuł:: NAC1 Maintains Root Meristem Activity by Repressing the Transcription of E2Fa in Arabidopsis .
Autorzy:: Xie C; The Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, College of Life Sciences, Shandong University, Qingdao 266237, China.
Ding Z; The Key Laboratory of Plant Development and Environmental Adaptation Biology, Ministry of Education, College of Life Sciences, Shandong University, Qingdao 266237, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 14; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:: Journal Article
MeSH Terms:: Arabidopsis*/metabolism
Arabidopsis Proteins*/metabolism
Meristem ; Gene Expression Regulation, Plant ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Plant Roots ; E2F Transcription Factors/genetics

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Skocz do pozycji: 12.

Tytuł:: Activation of E2F-dependent transcription by the mouse cytomegalovirus M117 protein affects the viral host range.
Autorzy:: Ostermann E; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Loroch S; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.
Qian Z; Unit of Herpesvirus and Molecular Virology, Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Sickmann A; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany.
Wiebusch L; Labor für Pädiatrische Molekularbiologie, Charité Universitätsmedizin Berlin, Berlin, Germany.
Brune W; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2018 Dec 10; Vol. 14 (12), pp. e1007481. Date of Electronic Publication: 2018 Dec 10 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: E2F Transcription Factors*
Virus Replication*
Herpesviridae Infections/*genetics
Host Specificity/*genetics
Muromegalovirus/*genetics
Animals ; Humans ; Mice

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Skocz do pozycji: 13.

Tytuł:: Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Autorzy:: Bove RM; Weill Institute for the Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Patrick E; Harvard Medical School, Boston, MA, United States of America.; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America.; School of Mathematics and Statistics, University of Sydney, Westmead, NSW, Australia.; The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia.
Aubin CM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America.
Srivastava G; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA, United States of America.
Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.
Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, United States of America.
De Jager PL; Harvard Medical School, Boston, MA, United States of America.; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA, United States of America.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America.; Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York City, NY, United States of America.
Chibnik LB; Harvard Medical School, Boston, MA, United States of America.; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, MA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 Jul 27; Vol. 13 (7), pp. e0199073. Date of Electronic Publication: 2018 Jul 27 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Epigenesis, Genetic*
Cognition/*physiology
E2F Transcription Factors/*genetics
Estradiol/*metabolism
Prefrontal Cortex/*metabolism
Stroke/*genetics
Aged, 80 and over ; Autopsy ; CpG Islands ; DNA Methylation ; DNA Repair ; Disease Susceptibility ; E2F Transcription Factors/metabolism ; Estradiol/pharmacology ; Fatty Acids/genetics ; Fatty Acids/metabolism ; Female ; Humans ; Lipid Metabolism/genetics ; Mechanistic Target of Rapamycin Complex 1/genetics ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Oxidative Phosphorylation/drug effects ; Prefrontal Cortex/pathology ; Prospective Studies ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Reproduction ; Stroke/diagnosis ; Stroke/pathology

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Skocz do pozycji: 14.

Tytuł:: Positive regulation of ataxia-telangiectasia-mutated protein (ATM) by E2F transcription Factor 1 (E2F-1) in cisplatin-resistant nasopharyngeal carcinoma cells.
Autorzy:: Zhou ZY; Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, 434000, China.
Yang JY; Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, 434000, China.
Shao CZ; Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, 434000, China.
Luo F; Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, 434000, China.
Du W; Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, 434000, China. duweiweidu_.; Pokaż więcej
Źródło:: World journal of surgical oncology [World J Surg Oncol] 2022 Mar 18; Vol. 20 (1), pp. 88. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:: Journal Article
MeSH Terms:: Ataxia Telangiectasia*
Nasopharyngeal Neoplasms*/drug therapy
Nasopharyngeal Neoplasms*/genetics
Nasopharyngeal Neoplasms*/metabolism
E2F1 Transcription Factor/*metabolism
Apoptosis ; Ataxia Telangiectasia Mutated Proteins/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/pharmacology ; Cell Line, Tumor ; Cisplatin/pharmacology ; Drug Resistance, Neoplasm ; E2F Transcription Factors/metabolism ; Humans ; Nasopharyngeal Carcinoma/genetics

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Skocz do pozycji: 15.

Tytuł:: Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Autorzy:: Kumari R; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK.
Hummerich H; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK.
Shen X; The UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6DD, UK.
Fischer M; Computational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Beutenbergstraße 11, 07745, Jena, Germany.
Litovchick L; Division of Hematology, Oncology and Palliative Care, Department of Internal Medicine, Massey Cancer Centre, Virginia Commonwealth University, Richmond, VA, 23298, USA.
Mittnacht S; The UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6DD, UK.
DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02115, USA.
Jat PS; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 02; Vol. 11 (1), pp. 21506. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cellular Senescence*
Gene Expression Regulation*
Breast/*metabolism
Cell Cycle Proteins/*metabolism
Fibroblasts/*metabolism
Forkhead Box Protein M1/*metabolism
Multiprotein Complexes/*metabolism
Trans-Activators/*metabolism
Breast/cytology ; Cell Cycle Proteins/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Female ; Fibroblasts/cytology ; Forkhead Box Protein M1/genetics ; Humans ; Kv Channel-Interacting Proteins/genetics ; Kv Channel-Interacting Proteins/metabolism ; Multiprotein Complexes/genetics ; Phosphorylation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism ; Trans-Activators/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; YAP-Signaling Proteins/genetics ; YAP-Signaling Proteins/metabolism

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Skocz do pozycji: 16.

Tytuł:: RB depletion is required for the continuous growth of tumors initiated by loss of RB.
Autorzy:: Doan A; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.
Arand J; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.; Center of Anatomy and Cell Biology, Department of Cell and Developmental Biology, Medical University of Vienna, Vienna, Austria.
Gong D; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.; Department of Bioengineering, Stanford University, Stanford, California, United States of America.
Drainas AP; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.
Shue YT; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.
Lee MC; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.
Zhang S; Department of Biology, Stanford University, Stanford, California, United States of America.
Walter DM; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Chaikovsky AC; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.
Feldser DM; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Vogel H; Department of Pathology, Stanford University, Stanford, California, United States of America.
Dow LE; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York, United States of America.; Department of Biochemistry, Weill Cornell Medicine, New York, New York, United States of America.; Department of Medicine, Weill Cornell Medicine, New York, New York, United States of America.
Skotheim JM; Department of Biology, Stanford University, Stanford, California, United States of America.
Sage J; Department of Pediatrics, Stanford University, Stanford, California, United States of America.; Department of Genetics, Stanford University, Stanford, California, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2021 Dec 08; Vol. 17 (12), pp. e1009941. Date of Electronic Publication: 2021 Dec 08 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Pituitary Neoplasms/*genetics
Retinoblastoma Binding Proteins/*genetics
Thyroid Neoplasms/*genetics
Animals ; Cell Cycle Checkpoints/genetics ; Cell Line, Tumor ; Disease Models, Animal ; E2F Transcription Factors/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Male ; Mice ; Mice, Transgenic ; NIH 3T3 Cells ; Pituitary Neoplasms/pathology ; RNA, Small Interfering/metabolism ; Thyroid Neoplasms/pathology

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Skocz do pozycji: 17.

Tytuł:: Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.
Autorzy:: Fischer M; a Molecular Oncology, Medical School, University of Leipzig , Leipzig , Germany.; b Department of Medical Oncology , Dana-Farber Cancer Institute , Boston , MA , USA.; c Department of Medicine, Brigham and Women's Hospital , Harvard Medical School , Boston , MA , USA.
Müller GA; a Molecular Oncology, Medical School, University of Leipzig , Leipzig , Germany.; Pokaż więcej
Źródło:: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2017 Dec; Vol. 52 (6), pp. 638-662. Date of Electronic Publication: 2017 Aug 11.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Cycle*
Transcriptional Activation*
E2F Transcription Factors/*metabolism
Kv Channel-Interacting Proteins/*metabolism
Nuclear Proteins/*metabolism
Repressor Proteins/*metabolism
Retinoblastoma Protein/*metabolism
Trans-Activators/*metabolism
Animals ; Cell Differentiation ; E2F Transcription Factors/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Kv Channel-Interacting Proteins/genetics ; Neoplasms/genetics ; Neoplasms/metabolism ; Nuclear Proteins/genetics ; Protein Interaction Maps ; Repressor Proteins/genetics ; Retinoblastoma Protein/genetics ; Trans-Activators/genetics ; Transcription, Genetic

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Skocz do pozycji: 18.

Tytuł:: SOG1 transcription factor promotes the onset of endoreduplication under salinity stress in Arabidopsis.
Autorzy:: Mahapatra K; Department of Botany, UGC Center for Advanced Studies, The University of Burdwan, Golapbag Campus, Burdwan, West Bengal, 713 104, India.
Roy S; Department of Botany, UGC Center for Advanced Studies, The University of Burdwan, Golapbag Campus, Burdwan, West Bengal, 713 104, India. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 02; Vol. 11 (1), pp. 11659. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication
MeSH Terms:: Endoreduplication*
Arabidopsis/*genetics
Arabidopsis Proteins/*genetics
Ataxia Telangiectasia Mutated Proteins/*genetics
DNA, Plant/*genetics
Salt Tolerance/*genetics
Transcription Factors/*genetics
Arabidopsis/drug effects ; Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Size ; Cyclin B/genetics ; Cyclin B/metabolism ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; DNA, Plant/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; G2 Phase Cell Cycle Checkpoints/genetics ; Gene Expression Regulation, Plant ; Plant Cells/drug effects ; Plant Cells/metabolism ; Polyploidy ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Salt Stress/genetics ; Signal Transduction ; Sodium Chloride/pharmacology ; Transcription Factors/metabolism

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Skocz do pozycji: 19.

Tytuł:: The multifaceted role of cell cycle regulators in the coordination of growth and metabolism.
Autorzy:: Huber K; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Mestres-Arenas A; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Fajas L; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Leal-Esteban LC; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2021 Jun; Vol. 288 (12), pp. 3813-3833. Date of Electronic Publication: 2020 Oct 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Cell Cycle/*genetics
Cyclin-Dependent Kinase Inhibitor Proteins/*genetics
Cyclin-Dependent Kinases/*genetics
Cyclins/*genetics
Nutritive Value/*physiology
Adaptation, Physiological ; Animals ; Cell Cycle/drug effects ; Cells, Cultured ; Cyclin-Dependent Kinase Inhibitor Proteins/metabolism ; Cyclin-Dependent Kinases/antagonists & inhibitors ; Cyclin-Dependent Kinases/metabolism ; Cyclins/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Endosomes/drug effects ; Endosomes/metabolism ; Gene Expression Regulation ; Humans ; Lysosomes/drug effects ; Lysosomes/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Protein Kinase Inhibitors/pharmacology ; Retinoblastoma Protein/genetics ; Retinoblastoma Protein/metabolism ; Saccharomyces cerevisiae/drug effects ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae/metabolism ; Signal Transduction

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Skocz do pozycji: 20.

Tytuł:: Enhanced Rb/E2F and TSC/mTOR Pathways Induce Synergistic Inhibition in PDGF-Induced Proliferation in Vascular Smooth Muscle Cells.
Autorzy:: Li Y; Department of Cardiac surgery, Air Force General Hospital of People`s Liberation Army, Beijing, China.
Li X; Department of Vascular and Thyroid Surgery, 1st Hospital of China Medical University, Shenyang, Liaoning, China.
Liu J; Department of Vascular and Endovascular Surgery, General Hospital of People`s Liberation Army, Beijing, China.; Vascular Surgery Research Laboratories, Division of Vascular and Endovascular Suregery, Brigham and Woman's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Guo W; Department of Vascular and Endovascular Surgery, General Hospital of People`s Liberation Army, Beijing, China.
Zhang H; Department of Cardiac surgery, Air Force General Hospital of People`s Liberation Army, Beijing, China.
Wang J; Department of Cardiac surgery, Air Force General Hospital of People`s Liberation Army, Beijing, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Jan 11; Vol. 12 (1), pp. e0170036. Date of Electronic Publication: 2017 Jan 11 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Cell Proliferation/*drug effects
E2F Transcription Factors/*physiology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Platelet-Derived Growth Factor/*pharmacology
Retinoblastoma Protein/*physiology
Calcium-Binding Proteins/metabolism ; Calcium-Binding Proteins/physiology ; Cells, Cultured ; E2F Transcription Factors/metabolism ; Humans ; Muscle, Smooth, Vascular/physiology ; Myocytes, Smooth Muscle/physiology ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Retinoblastoma Protein/metabolism ; Signal Transduction/drug effects ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/physiology ; Up-Regulation/drug effects

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