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Wyszukujesz frazę ""E2F Transcription Factors"" wg kryterium: Temat


Tytuł:
Cryptochromes modulate E2F family transcription factors.
Autorzy:
Chan AB; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Huber AL; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.; Centre de Recherche en Cancerologie de Lyon, 28 rue Laennec, 69008, Lyon, France.
Lamia KA; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 05; Vol. 10 (1), pp. 4077. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Circadian Rhythm*
Gene Expression Regulation*
Cryptochromes/*physiology
E2F Transcription Factors/*metabolism
Transcription Factors/*metabolism
Ubiquitin-Protein Ligase Complexes/*metabolism
Animals ; E2F Transcription Factors/genetics ; Mice, Knockout ; Transcription Factors/genetics ; Ubiquitin-Protein Ligase Complexes/genetics
Czasopismo naukowe
Tytuł:
Overexpression and alternative splicing of NF-YA in breast cancer.
Autorzy:
Dolfini D; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.
Andrioletti V; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.; Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Germany.
Mantovani R; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2019 Sep 10; Vol. 9 (1), pp. 12955. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
BRCA1 Protein/*metabolism
BRCA2 Protein/*metabolism
Biomarkers, Tumor/*genetics
Breast Neoplasms/*pathology
CCAAT-Binding Factor/*genetics
E2F Transcription Factors/*metabolism
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; CCAAT-Binding Factor/metabolism ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; E2F Transcription Factors/genetics ; Female ; Gene Expression Profiling ; Humans ; Promoter Regions, Genetic ; Protein Binding ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.
Autorzy:
Lan W; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.; Aix-Marseille Université, CNRS, Centre Interdisciplinaire de Nanoscience de Marseille, UMR 7325, «Equipe Labellisée Ligue Contre le Cancer», Marseille, France.
Bian B; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.
Xia Y; Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing, China.
Dou S; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.
Gayet O; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.
Bigonnet M; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.
Santofimia-Castaño P; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France.
Cong M; Aix-Marseille Université, CNRS, Centre Interdisciplinaire de Nanoscience de Marseille, UMR 7325, «Equipe Labellisée Ligue Contre le Cancer», Marseille, France.
Peng L; Aix-Marseille Université, CNRS, Centre Interdisciplinaire de Nanoscience de Marseille, UMR 7325, «Equipe Labellisée Ligue Contre le Cancer», Marseille, France.
Dusetti N; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France. .
Iovanna J; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France. .
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Źródło:
Scientific reports [Sci Rep] 2018 May 29; Vol. 8 (1), pp. 8330. Date of Electronic Publication: 2018 May 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Pancreatic Ductal/*classification
E2F Transcription Factors/*metabolism
Pancreatic Neoplasms/*classification
Animals ; Antimetabolites, Antineoplastic/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Apoptosis/drug effects ; Carcinoma, Pancreatic Ductal/drug therapy ; Carcinoma, Pancreatic Ductal/metabolism ; Carcinoma, Pancreatic Ductal/pathology ; Cell Line, Tumor ; E2F Transcription Factors/antagonists & inhibitors ; E2F Transcription Factors/genetics ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Mice ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Survival Analysis ; Transcriptome ; Xenograft Model Antitumor Assays ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Autorzy:
Kumari R; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK.
Hummerich H; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK.
Shen X; The UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6DD, UK.
Fischer M; Computational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Beutenbergstraße 11, 07745, Jena, Germany.
Litovchick L; Division of Hematology, Oncology and Palliative Care, Department of Internal Medicine, Massey Cancer Centre, Virginia Commonwealth University, Richmond, VA, 23298, USA.
Mittnacht S; The UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6DD, UK.
DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02115, USA.
Jat PS; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, 33 Cleveland Street, London, W1W 7FF, UK. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 02; Vol. 11 (1), pp. 21506. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cellular Senescence*
Gene Expression Regulation*
Breast/*metabolism
Cell Cycle Proteins/*metabolism
Fibroblasts/*metabolism
Forkhead Box Protein M1/*metabolism
Multiprotein Complexes/*metabolism
Trans-Activators/*metabolism
Breast/cytology ; Cell Cycle Proteins/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Female ; Fibroblasts/cytology ; Forkhead Box Protein M1/genetics ; Humans ; Kv Channel-Interacting Proteins/genetics ; Kv Channel-Interacting Proteins/metabolism ; Multiprotein Complexes/genetics ; Phosphorylation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism ; Trans-Activators/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; YAP-Signaling Proteins/genetics ; YAP-Signaling Proteins/metabolism
Czasopismo naukowe
Tytuł:
Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.
Autorzy:
Youn HS; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
Kim TY; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
Park UH; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
Moon ST; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
An SJ; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
Lee YK; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea.
Hwang JT; Korea Food Research Institute, Bundang-gu, Seongnam-si, 463-746, Korea.
Kim EJ; Department of Molecular Biology, Dankook University, Gyeonggi-do, 448-701, Korea.
Um SJ; Department of Bioscience and Biotechnology, BK21 Graduate Program, Sejong University, 209 Neungdong-ro, Gwangjin-gu, Seoul, 143-747, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2017 Jul 12; Vol. 7 (1), pp. 5198. Date of Electronic Publication: 2017 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cellular Senescence*
E2F Transcription Factors/*antagonists & inhibitors
Embryo, Mammalian/*pathology
Enhancer of Zeste Homolog 2 Protein/*antagonists & inhibitors
Fibroblasts/*pathology
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Repressor Proteins/*physiology
Animals ; Cell Proliferation ; Cells, Cultured ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Embryo, Mammalian/metabolism ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Fibroblasts/metabolism ; Mice ; Mice, Knockout ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
SOG1 transcription factor promotes the onset of endoreduplication under salinity stress in Arabidopsis.
Autorzy:
Mahapatra K; Department of Botany, UGC Center for Advanced Studies, The University of Burdwan, Golapbag Campus, Burdwan, West Bengal, 713 104, India.
Roy S; Department of Botany, UGC Center for Advanced Studies, The University of Burdwan, Golapbag Campus, Burdwan, West Bengal, 713 104, India. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jun 02; Vol. 11 (1), pp. 11659. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication
MeSH Terms:
Endoreduplication*
Arabidopsis/*genetics
Arabidopsis Proteins/*genetics
Ataxia Telangiectasia Mutated Proteins/*genetics
DNA, Plant/*genetics
Salt Tolerance/*genetics
Transcription Factors/*genetics
Arabidopsis/drug effects ; Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Size ; Cyclin B/genetics ; Cyclin B/metabolism ; Cyclin-Dependent Kinases/genetics ; Cyclin-Dependent Kinases/metabolism ; DNA, Plant/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; G2 Phase Cell Cycle Checkpoints/genetics ; Gene Expression Regulation, Plant ; Plant Cells/drug effects ; Plant Cells/metabolism ; Polyploidy ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Salt Stress/genetics ; Signal Transduction ; Sodium Chloride/pharmacology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Tiliroside as a CAXII inhibitor suppresses liver cancer development and modulates E2Fs/Caspase-3 axis.
Autorzy:
Han R; Department of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, People's Republic of China. .; Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, 06520, USA. .
Yang H; Department of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, People's Republic of China.
Lu L; Department of Chronic Disease Epidemiology, Yale School of Public Health, School of Medicine, Yale University, New Haven, CT, 06520-8034, USA.
Lin L; Department of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 21; Vol. 11 (1), pp. 8626. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Carbonic Anhydrases/*metabolism
Caspase 3/*metabolism
E2F Transcription Factors/*metabolism
Enzyme Inhibitors/*pharmacology
Flavonoids/*pharmacology
Liver Neoplasms/*drug therapy
Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Liver Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors.
Autorzy:
Andrechek ER; Department of Physiology, Michigan State University, East Lansing, MI, USA.
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Źródło:
Oncogene [Oncogene] 2015 Jan 08; Vol. 34 (2), pp. 217-25. Date of Electronic Publication: 2013 Dec 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Breast Neoplasms/*metabolism
E2F Transcription Factors/*metabolism
Mammary Neoplasms, Experimental/*metabolism
Receptor, ErbB-2/*metabolism
Animals ; Breast Neoplasms/enzymology ; Breast Neoplasms/pathology ; Carcinogenesis ; Disease Models, Animal ; E2F Transcription Factors/deficiency ; E2F Transcription Factors/genetics ; Female ; Humans ; Mammary Neoplasms, Experimental/enzymology ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Knockout ; Mice, Nude ; Neoplasm Metastasis ; Neoplastic Cells, Circulating/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł:
Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway.
Autorzy:
Zou ZV; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Gul N; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Lindberg M; Department of Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Bokhari AA; Department of Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Eklund EM; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Garellick V; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Patel AAH; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Dzanan JJ; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Titmuss BO; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Le Gal K; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Johansson I; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Tivesten Å; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Forssell-Aronsson E; Sahlgrenska Cancer Center, Department of Radiation Physics, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.; Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Bergö MO; Sahlgrenska Cancer Center, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.; Department of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden.
Staffas A; Department of Microbiologi and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Larsson E; Department of Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Sayin VI; Sahlgrenska Cancer Center, Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden. .; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden. .
Lindahl P; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden. .; Department of Biochemistry, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden. .
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14156. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA-Binding Proteins/*genetics
Gene Expression Regulation/*genetics
Signal Transduction/*genetics
Transcription Factors/*genetics
Tumor Suppressor Protein p53/*physiology
Animals ; CRISPR-Cas Systems ; Cell Cycle Checkpoints/genetics ; Cell Cycle Proteins/biosynthesis ; Cell Cycle Proteins/genetics ; Cell Division ; Cell Line ; Chromatin Immunoprecipitation ; Cisplatin/toxicity ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; DNA Damage ; DNA-Binding Proteins/deficiency ; DNA-Binding Proteins/physiology ; Down-Regulation ; E2F Transcription Factors/physiology ; Etoposide/toxicity ; Fibroblasts ; Gene Ontology ; Mice ; RNA Interference ; RNA, Small Interfering/genetics ; Transcription Factors/deficiency ; Transcription Factors/physiology
Czasopismo naukowe
Tytuł:
Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation.
Autorzy:
Tretina K; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Program in Molecular Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Haidar M; Laboratoire de Biologie Comparative des Apicomplexes, Faculté de Médicine, Université Paris Descartes, Sorbonne, Paris Cité, France.; Inserm U1016, Cnrs UMR8104, Cochin Institute, Paris, 75014, France.
Madsen-Bouterse SA; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164-7040, USA.
Sakura T; Laboratoire de Biologie Comparative des Apicomplexes, Faculté de Médicine, Université Paris Descartes, Sorbonne, Paris Cité, France.; Inserm U1016, Cnrs UMR8104, Cochin Institute, Paris, 75014, France.
Mfarrej S; Pathogen Genomics Laboratory, Biological and Environmental Sciences and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Fry L; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164-7040, USA.; Animal Disease Research Unit, Agricultural Research Service, USDA, Pullman, WA, 99164-7030, USA.
Chaussepied M; Laboratoire de Biologie Comparative des Apicomplexes, Faculté de Médicine, Université Paris Descartes, Sorbonne, Paris Cité, France.; Inserm U1016, Cnrs UMR8104, Cochin Institute, Paris, 75014, France.; Weizmann Institute of Science, Molecular Cell Biology Department, PO Box 26, Rehovot, 76100, Israel.
Pain A; Pathogen Genomics Laboratory, Biological and Environmental Sciences and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Knowles DP; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164-7040, USA.
Nene VM; International Livestock Research Institute, Nairobi, 00100, Kenya.
Ginsberg D; Weizmann Institute of Science, Molecular Cell Biology Department, PO Box 26, Rehovot, 76100, Israel.; The Mina and Everard Goodman Faculty of Life Sciences Bar-Ilan University, Ramat-Gan, 52900, Israel.
Daubenberger CA; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland.
Bishop RP; Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, 99164-7040, USA.
Langsley G; Laboratoire de Biologie Comparative des Apicomplexes, Faculté de Médicine, Université Paris Descartes, Sorbonne, Paris Cité, France.; Inserm U1016, Cnrs UMR8104, Cochin Institute, Paris, 75014, France.
Silva JC; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 04; Vol. 10 (1), pp. 3982. Date of Electronic Publication: 2020 Mar 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Signal Transduction*
E2F Transcription Factors/*metabolism
Leukocytes/*cytology
Leukocytes/*parasitology
Theileria/*physiology
Cell Line ; Cell Proliferation ; E2F1 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł:
Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status.
Autorzy:
Dueñas M; Molecular Oncology Unit, CIEMAT, Avda Complutense 40, 28040, Madrid, Spain.; Biomedical Research Institute, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041, Madrid, Spain.; CIBERONC, Biomedical Research Networking Centers, Madrid, Spain.
Pérez-Figueroa A; Phylogenomics Lab. Department of Biochemistry, Genetics an Immunology & Biomedical Research Center (CINBIO), University of Vigo, 36310, Vigo, Spain.
Oliveira C; Expression Regulation in Cancer Lab, Universidade do Porto, i3s & IPATIMUP. Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Suárez-Cabrera C; Molecular Oncology Unit, CIEMAT, Avda Complutense 40, 28040, Madrid, Spain.; Biomedical Research Institute, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041, Madrid, Spain.; CIBERONC, Biomedical Research Networking Centers, Madrid, Spain.
Sousa A; Expression Regulation in Cancer Lab, Universidade do Porto, i3s & IPATIMUP. Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Oliveira P; Expression Regulation in Cancer Lab, Universidade do Porto, i3s & IPATIMUP. Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.
Villacampa F; Biomedical Research Institute, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041, Madrid, Spain.; CIBERONC, Biomedical Research Networking Centers, Madrid, Spain.; Urology Department, Clinica Universidad de Navarra, Madrid, Spain.
Paramio JM; Molecular Oncology Unit, CIEMAT, Avda Complutense 40, 28040, Madrid, Spain. .; Biomedical Research Institute, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041, Madrid, Spain. .; CIBERONC, Biomedical Research Networking Centers, Madrid, Spain. .
Martínez-Fernández M; Molecular Oncology Unit, CIEMAT, Avda Complutense 40, 28040, Madrid, Spain. .; Biomedical Research Institute, Hospital Universitario 12 de Octubre, Avda Córdoba s/n, 28041, Madrid, Spain. .; CIBERONC, Biomedical Research Networking Centers, Madrid, Spain. .; Genomes and Disease Lab. Center for Molecular Medicine and Chronic Diseases Research (CIMUS), Universidade de Santiago de Compostela (USC), Avda de Barcelona, 31, 15706, Santiago de Compostela, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2019 Jul 17; Vol. 9 (1), pp. 10362. Date of Electronic Publication: 2019 Jul 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
Gene Expression Regulation, Neoplastic*
Genes, p53*
Carcinoma, Transitional Cell/*genetics
Papilloma/*genetics
Urinary Bladder Neoplasms/*genetics
Carcinoma, Transitional Cell/pathology ; Disease-Free Survival ; E2F Transcription Factors/genetics ; Exons/genetics ; Gene Ontology ; Genes, myc ; Humans ; Kaplan-Meier Estimate ; Mutation, Missense ; Neoplasm Invasiveness ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Papilloma/pathology ; Prognosis ; Proto-Oncogene Proteins c-mdm2/genetics ; Proto-Oncogene Proteins c-myc/genetics ; Recurrence ; Tissue Array Analysis ; Urinary Bladder Neoplasms/pathology ; Exome Sequencing
Czasopismo naukowe
Tytuł:
Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells.
Autorzy:
Dattilo MA; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Benzo Y; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Herrera LM; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Prada JG; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Castillo AF; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Orlando UD; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Podesta EJ; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina.
Maloberti PM; Biomedical Research Institute, INBIOMED, Department of Biochemistry, School of Medicine, University of Buenos Aires, CABA, Buenos Aires, Argentina. .
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Źródło:
Scientific reports [Sci Rep] 2019 Jul 16; Vol. 9 (1), pp. 10324. Date of Electronic Publication: 2019 Jul 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Promoter Regions, Genetic*
Up-Regulation*
Coenzyme A Ligases/*genetics
Triple Negative Breast Neoplasms/*genetics
Cell Line, Tumor ; Coenzyme A Ligases/metabolism ; E2F Transcription Factors/metabolism ; Estrogen Receptor alpha/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; MCF-7 Cells ; Mutagenesis, Site-Directed ; Nuclear Receptor Subfamily 1, Group F, Member 1/metabolism ; Sp1 Transcription Factor/metabolism ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
Co-regulatory Network of Oncosuppressor miRNAs and Transcription Factors for Pathology of Human Hepatic Cancer Stem Cells (HCSC).
Autorzy:
Mohamed RH; Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt.
Abu-Shahba N; Stem Cell Research Group, Centre of Excellence for Advanced Sciences, Department of Medical Molecular Genetics, National Research Centre, Cairo, Egypt.
Mahmoud M; Stem Cell Research Group, Centre of Excellence for Advanced Sciences, Department of Medical Molecular Genetics, National Research Centre, Cairo, Egypt.
Abdelfattah AMH; Department of Mathematics, Faculty of Science, Ain Shams University, Cairo, Egypt.; VAP, CS Department, SUNY, Oswego, NY, USA.
Zakaria W; Department of Mathematics, Faculty of Science, Ain Shams University, Cairo, Egypt.
ElHefnawi M; Biomedical informatics and Chemoinformatics group, Centre of Excellence for Advanced Sciences, Informatics and Systems Department, National Research Centre, Cairo, Egypt. .; Informatics and systems Department, Division of Engineering research, National Research Centre, Cairo, Egypt. .
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Źródło:
Scientific reports [Sci Rep] 2019 Apr 03; Vol. 9 (1), pp. 5564. Date of Electronic Publication: 2019 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Regulatory Networks*
Liver Neoplasms/*pathology
MicroRNAs/*genetics
Neoplastic Stem Cells/*physiology
Transcription Factors/*genetics
E2F Transcription Factors/genetics ; Feedback, Physiological ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Genes, Tumor Suppressor ; Humans ; Large Neutral Amino Acid-Transporter 1/genetics ; Liver Neoplasms/genetics ; Neoplastic Stem Cells/pathology ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł:
A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest.
Autorzy:
Angus SP; Duke Institute for Genome Sciences & Policy, Duke University Medical Center, Durham, NC, USA.
Nevins JR
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Źródło:
Oncogene [Oncogene] 2012 Nov 01; Vol. 31 (44), pp. 4709-17. Date of Electronic Publication: 2012 Jan 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Cycle Checkpoints*/genetics
E2F Transcription Factors/*metabolism
Mediator Complex/*metabolism
Retinoblastoma Protein/*metabolism
Animals ; Cell Line ; Cellular Senescence/genetics ; E2F Transcription Factors/genetics ; E2F5 Transcription Factor/genetics ; E2F5 Transcription Factor/metabolism ; Gene Expression Regulation ; Humans ; Mice ; Protein Binding ; Protein Interaction Mapping/methods ; RNA, Small Interfering/metabolism ; Retinoblastoma Protein/genetics
Czasopismo naukowe
Tytuł:
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Autorzy:
Chong JL; Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.
Wenzel PL
Sáenz-Robles MT
Nair V
Ferrey A
Hagan JP
Gomez YM
Sharma N
Chen HZ
Ouseph M
Wang SH
Trikha P
Culp B
Mezache L
Winton DJ
Sansom OJ
Chen D
Bremner R
Cantalupo PG
Robinson ML
Pipas JM
Leone G
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Źródło:
Nature [Nature] 2009 Dec 17; Vol. 462 (7275), pp. 930-4.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cell Differentiation*
Gene Expression Regulation*
E2F Transcription Factors/*metabolism
Embryonic Stem Cells/*cytology
Embryonic Stem Cells/*metabolism
Repressor Proteins/*metabolism
Alleles ; Animals ; Apoptosis ; Cell Cycle/genetics ; Cell Cycle/physiology ; Cell Proliferation ; E2F Transcription Factors/deficiency ; E2F Transcription Factors/genetics ; E2F1 Transcription Factor/deficiency ; E2F1 Transcription Factor/genetics ; E2F1 Transcription Factor/metabolism ; E2F2 Transcription Factor/deficiency ; E2F2 Transcription Factor/genetics ; E2F2 Transcription Factor/metabolism ; E2F3 Transcription Factor/deficiency ; E2F3 Transcription Factor/genetics ; E2F3 Transcription Factor/metabolism ; Embryo, Mammalian/cytology ; Embryo, Mammalian/metabolism ; Female ; Intestine, Small/cytology ; Intestine, Small/metabolism ; Mice ; Mice, Transgenic ; Repressor Proteins/deficiency ; Repressor Proteins/genetics ; Retinoblastoma Protein/deficiency ; Retinoblastoma Protein/metabolism
Czasopismo naukowe
Tytuł:
Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy.
Autorzy:
Eelen G; Laboratorium voor Experimentele Geneeskunde en Endocrinologie (LEGENDO), Katholieke Universiteit Leuven, Leuven, Belgium.
Vanden Bempt I
Verlinden L
Drijkoningen M
Smeets A
Neven P
Christiaens MR
Marchal K
Bouillon R
Verstuyf A
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Źródło:
Oncogene [Oncogene] 2008 Jul 10; Vol. 27 (30), pp. 4233-41. Date of Electronic Publication: 2008 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*genetics
Carcinoma/*genetics
DNA-Binding Proteins/*genetics
E2F Transcription Factors/*physiology
RNA Helicases/*genetics
Animals ; Base Sequence ; Basic-Leucine Zipper Transcription Factors/genetics ; Binding Sites ; Breast Neoplasms/pathology ; Carcinoma/pathology ; Conserved Sequence ; E2F Transcription Factors/metabolism ; Fanconi Anemia Complementation Group Proteins/genetics ; Female ; Humans ; Mice ; Molecular Sequence Data ; Neoplasm Invasiveness ; Sequence Homology, Nucleic Acid ; Transcription, Genetic ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Overexpression of SERTAD3, a putative oncogene located within the 19q13 amplicon, induces E2F activity and promotes tumor growth.
Autorzy:
Darwish H; Faculty of Medicine, Department of Medicine, Lady Davis Institute for Medical Research and Segal Comprehensive Cancer Center of the Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Cho JM
Loignon M
Alaoui-Jamali MA
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Źródło:
Oncogene [Oncogene] 2007 Jun 21; Vol. 26 (29), pp. 4319-28. Date of Electronic Publication: 2007 Jan 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
E2F Transcription Factors/*biosynthesis
Gene Expression Regulation, Neoplastic/*physiology
Neoplasms, Experimental/*metabolism
Neoplasms, Experimental/*pathology
Oncogene Proteins/*biosynthesis
Oncogene Proteins/*genetics
Trans-Activators/*biosynthesis
Trans-Activators/*genetics
Amino Acid Sequence ; Animals ; Cell Line ; Cell Line, Tumor ; Chromosomes, Human, Pair 19/genetics ; E2F Transcription Factors/metabolism ; Gene Amplification ; Humans ; Mice ; Molecular Sequence Data ; NIH 3T3 Cells ; Oncogene Proteins/physiology ; Sequence Homology, Amino Acid ; Trans-Activators/physiology
Czasopismo naukowe

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