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Wyszukujesz frazę ""E2F Transcription Factors"" wg kryterium: Temat


Tytuł:
MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.
Autorzy:
Álvaro-Blanco J; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.
Urso K; Gene regulation in cardiovascular remodeling and inflammation group, Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain.
Chiodo Y; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.
Martín-Cortázar C; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.
Kourani O; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.
Arco PG; Gene regulation in cardiovascular remodeling and inflammation group, Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain.; Department of Molecular Biology, Universidad Autónoma de Madrid, Centro de Biología Molecular, Cantoblanco, Madrid 28049, Spain.; CIBERCV, Spain.
Rodríguez-Martínez M; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.
Calonge E; Unidad de Inmunopatología del SIDA, Centro Nacional de Microbiología, Majadahonda 28220, Spain.
Alcamí J; Unidad de Inmunopatología del SIDA, Centro Nacional de Microbiología, Majadahonda 28220, Spain.
Redondo JM; Gene regulation in cardiovascular remodeling and inflammation group, Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain.; CIBERCV, Spain.
Iglesias T; Department of Endocrine and Nervous Systems Pathophysiology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.; CIBERNED, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Spain.
Campanero MR; Department of Cancer Biology, Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, Madrid 28029, Spain.; CIBERCV, Spain.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2017 Sep 29; Vol. 45 (17), pp. 9960-9975.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*
Promoter Regions, Genetic*
DNA-Binding Proteins/*genetics
E2F Transcription Factors/*genetics
G1 Phase/*genetics
Oncogene Proteins v-myb/*genetics
Transcription Factors/*genetics
Binding Sites ; Cell Line, Tumor ; Crk-Associated Substrate Protein/genetics ; Crk-Associated Substrate Protein/metabolism ; DNA-Binding Proteins/antagonists & inhibitors ; DNA-Binding Proteins/metabolism ; E2F Transcription Factors/metabolism ; Genes, Reporter ; HEK293 Cells ; Humans ; Jurkat Cells ; Luciferases/genetics ; Luciferases/metabolism ; Lymphocytes/cytology ; Lymphocytes/metabolism ; Oncogene Proteins v-myb/metabolism ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Protein Binding ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Retinoblastoma Protein/genetics ; Retinoblastoma Protein/metabolism ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.
Autorzy:
Miller JG; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
Liu Y; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
Williams CW; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
Smith HE; Genomics Core, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
O'Connell KF; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 .
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2016 Jan 15; Vol. 6 (3), pp. 709-20. Date of Electronic Publication: 2016 Jan 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:
Caenorhabditis elegans/*metabolism
Centrioles/*metabolism
E2F Transcription Factors/*metabolism
Multiprotein Complexes/*metabolism
Transcription Factor DP1/*metabolism
Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Cell Division/genetics ; E2F Transcription Factors/antagonists & inhibitors ; Gene Expression Regulation ; Genes, Lethal ; Genome, Helminth ; Mutation ; Transcription Factor DP1/antagonists & inhibitors ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer.
Autorzy:
Müller S; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Bley N; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Busch B; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Glaß M; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Lederer M; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Misiak C; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Fuchs T; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Wedler A; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Haase J; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Bertoldo JB; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
Michl P; Department of Internal Medicine I, Faculty of Medicine, Martin Luther University Halle/Wittenberg, 06120 Halle, Germany.
Hüttelmaier S; Institute of Molecular Medicine, Section for Molecular Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06120 Halle, Germany.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2020 Sep 04; Vol. 48 (15), pp. 8576-8590.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
E2F Transcription Factors/*genetics
Neoplasms/*genetics
RNA-Binding Proteins/*genetics
3' Untranslated Regions/genetics ; Animals ; Cell Line, Tumor ; E2F1 Transcription Factor/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Mice ; Neoplasms/pathology ; RNA-Binding Proteins/drug effects ; Small Molecule Libraries/pharmacology
Czasopismo naukowe
Tytuł:
DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation.
Autorzy:
Uxa S; Molecular Oncology, Department of Gynaecology, Medical School, Leipzig University, 04103 Leipzig, Germany.
Bernhart SH; Transcriptome Bioinformatics Group, Department of Computer Science and Interdisciplinary Center for Bioinformatics, Leipzig University, 04107 Leipzig, Germany.
Mages CFS; Molecular Oncology, Department of Gynaecology, Medical School, Leipzig University, 04103 Leipzig, Germany.
Fischer M; Computational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), 07745 Jena, Germany.
Kohler R; Molecular Oncology, Department of Gynaecology, Medical School, Leipzig University, 04103 Leipzig, Germany.
Hoffmann S; Computational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), 07745 Jena, Germany.
Stadler PF; Transcriptome Bioinformatics Group, Department of Computer Science and Interdisciplinary Center for Bioinformatics, Leipzig University, 04107 Leipzig, Germany.; German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig; Leipzig Research Center for Civilization Diseases; and Competence Center for Scalable Data Services and Solutions Dresden/Leipzig, Leipzig University, 04107 Leipzig, Germany.; Max Planck Institute for Mathematics in the Sciences, 04103 Leipzig, Germany.; Institute for Theoretical Chemistry, University of Vienna, A-1090 Wien, Austria.; Facultad de Ciencias, Universidad National de Colombia, Sede Bogota, Colombia.; Santa Fe Institute, Santa Fe, NM 87501, USA.
Engeland K; Molecular Oncology, Department of Gynaecology, Medical School, Leipzig University, 04103 Leipzig, Germany.
Müller GA; Molecular Oncology, Department of Gynaecology, Medical School, Leipzig University, 04103 Leipzig, Germany.; Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2019 Sep 26; Vol. 47 (17), pp. 9087-9103.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
Cell Cycle Checkpoints/*genetics
Kv Channel-Interacting Proteins/*metabolism
Repressor Proteins/*metabolism
Retinoblastoma Protein/*genetics
Trans-Activators/*physiology
Tumor Suppressor Protein p53/*metabolism
Animals ; Cells, Cultured ; Crk-Associated Substrate Protein/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; E2F Transcription Factors/genetics ; E2F Transcription Factors/metabolism ; Fibroblasts/metabolism ; Genes, cdc ; HCT116 Cells ; Humans ; Kv Channel-Interacting Proteins/genetics ; Mice ; Repressor Proteins/genetics ; Retinoblastoma Protein/metabolism ; Retinoblastoma-Like Protein p107/genetics ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target.
Autorzy:
Tian S; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. .
Siu FM; Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China. .
Lok CN; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. .
Fung YME; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. .
Che CM; Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China. .
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Źródło:
Metallomics : integrated biometal science [Metallomics] 2019 Nov 01; Vol. 11 (11), pp. 1925-1936. Date of Electronic Publication: 2019 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Targeted Therapy*
Antineoplastic Agents/*pharmacology
Auranofin/*pharmacology
Hydroxymethylglutaryl CoA Reductases/*metabolism
Cell Line, Tumor ; E2F Transcription Factors/metabolism ; Gold/pharmacology ; Humans ; Signal Transduction/drug effects ; Time Factors ; Tumor Suppressor Protein p14ARF/metabolism ; Tumor Suppressor Protein p53/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł:
Dynamic site-specific recruitment of RBP2 by pocket protein p130 modulates H3K4 methylation on E2F-responsive promoters.
Autorzy:
Zargar ZU; Laboratory of Cell Cycle Regulation, Centre for DNA Fingerprinting and Diagnostics (CDFD), Nampally, Hyderabad 500001, India.; Graduate Studies, Manipal University, Manipal, India.
Kimidi MR; Laboratory of Cell Cycle Regulation, Centre for DNA Fingerprinting and Diagnostics (CDFD), Nampally, Hyderabad 500001, India.
Tyagi S; Laboratory of Cell Cycle Regulation, Centre for DNA Fingerprinting and Diagnostics (CDFD), Nampally, Hyderabad 500001, India.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2018 Jan 09; Vol. 46 (1), pp. 174-188.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
E2F Transcription Factors/*metabolism
Histones/*metabolism
Promoter Regions, Genetic/*genetics
Retinoblastoma-Binding Protein 2/*metabolism
Retinoblastoma-Like Protein p130/*metabolism
Retinol-Binding Proteins, Cellular/*metabolism
Amino Acid Motifs/genetics ; Amino Acid Sequence ; Animals ; Cell Line ; Cells, Cultured ; E2F4 Transcription Factor/metabolism ; G1 Phase/genetics ; HeLa Cells ; Humans ; Methylation ; Mice ; Mutation ; Protein Binding ; RNA Interference ; Retinoblastoma-Binding Protein 2/genetics ; Retinoblastoma-Like Protein p130/genetics ; Retinol-Binding Proteins, Cellular/genetics
Czasopismo naukowe
Tytuł:
Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.
Autorzy:
Fischer M; Molecular Oncology, Medical School, University of Leipzig, Leipzig 04103, Germany Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Medicine, Harvard Medical School, Boston, MA 02215, USA _.
Grossmann P; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Padi M; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2016 Jul 27; Vol. 44 (13), pp. 6070-86. Date of Electronic Publication: 2016 Jun 08.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Forkhead Box Protein M1/*genetics
Kv Channel-Interacting Proteins/*genetics
Neoplasms/*genetics
Repressor Proteins/*genetics
Tumor Suppressor Protein p53/*genetics
Cell Cycle/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; E2F Transcription Factors/genetics ; Forkhead Box Protein M1/biosynthesis ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks/genetics ; Humans ; Kv Channel-Interacting Proteins/biosynthesis ; Neoplasms/pathology ; Promoter Regions, Genetic ; Repressor Proteins/biosynthesis ; Retinoblastoma Binding Proteins/genetics ; Tumor Suppressor Protein p53/biosynthesis ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł:
Hunting complex differential gene interaction patterns across molecular contexts.
Autorzy:
Song M; Department of Computer Science, New Mexico State University, Las Cruces, NM 88003, USA, Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA, Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA 98195, USA and German Cancer Research Center (DKFZ)-Center for Molecular Biology Heidelberg (ZMBH) Alliance, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany.
Zhang Y
Katzaroff AJ
Edgar BA
Buttitta L
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2014 Apr; Vol. 42 (7), pp. e57. Date of Electronic Publication: 2014 Jan 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Regulatory Networks*
Animals ; Cell Cycle/genetics ; Chi-Square Distribution ; Drosophila Proteins/physiology ; Drosophila melanogaster/genetics ; E2F Transcription Factors/physiology ; Gene Expression Profiling ; Transcription Factors/physiology ; Yeasts/genetics
Czasopismo naukowe
Tytuł:
The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes.
Autorzy:
Subtil-Rodríguez A; Molecular Biology Department, Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Consejo Superior de Investigaciones Científicas (CSIC), Av. Americo Vespucio 41092 Seville, Spain, Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, L'Hospitalet, Barcelona, Spain and Department of Anatomic Pathology, Pharmacology and Microbiology, University of Barcelona, Spain.
Vázquez-Chávez E
Ceballos-Chávez M
Rodríguez-Paredes M
Martín-Subero JI
Esteller M
Reyes JC
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2014 Feb; Vol. 42 (4), pp. 2185-96. Date of Electronic Publication: 2013 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcriptional Activation*
DNA-Binding Proteins/*metabolism
E2F Transcription Factors/*metabolism
S Phase/*genetics
Transcription Factors/*metabolism
Animals ; Cell Line ; E2F1 Transcription Factor/metabolism ; E2F3 Transcription Factor/metabolism ; Humans ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł:
Estradiol-regulated microRNAs control estradiol response in breast cancer cells.
Autorzy:
Bhat-Nakshatri P; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Wang G
Collins NR
Thomson MJ
Geistlinger TR
Carroll JS
Brown M
Hammond S
Srour EF
Liu Y
Nakshatri H
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2009 Aug; Vol. 37 (14), pp. 4850-61. Date of Electronic Publication: 2009 Jun 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*genetics
Estradiol/*pharmacology
MicroRNAs/*metabolism
Binding Sites ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; E2F Transcription Factors/biosynthesis ; E2F Transcription Factors/genetics ; Estrogen Receptor alpha/metabolism ; Female ; Humans ; MicroRNAs/genetics ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-myc/biosynthesis ; Proto-Oncogene Proteins c-myc/genetics ; Regulatory Elements, Transcriptional ; Ribonuclease III/biosynthesis ; Ribonuclease III/genetics
Czasopismo naukowe
Tytuł:
Identification of co-occurring transcription factor binding sites from DNA sequence using clustered position weight matrices.
Autorzy:
Oh YM; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.
Kim JK
Choi S
Yoo JY
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2012 Mar; Vol. 40 (5), pp. e38. Date of Electronic Publication: 2011 Dec 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Position-Specific Scoring Matrices*
Regulatory Elements, Transcriptional*
Sequence Analysis, DNA*
Transcription Factors/*metabolism
Base Sequence ; Binding Sites ; Conserved Sequence ; E2F Transcription Factors/metabolism ; Nucleotide Motifs ; Proto-Oncogene Proteins c-jun/metabolism ; Software
Czasopismo naukowe
Tytuł:
Designing small multiple-target artificial RNAs.
Autorzy:
De Guire V; Département de Biochimie, Université de Montréal, Montréal, QC H3C 3J7 Canada.
Caron M
Scott N
Ménard C
Gaumont-Leclerc MF
Chartrand P
Major F
Ferbeyre G
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2010 Jul; Vol. 38 (13), pp. e140. Date of Electronic Publication: 2010 May 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Algorithms*
Gene Expression Regulation*
MicroRNAs/*chemistry
Cell Line ; Cell Line, Tumor ; Cell Proliferation ; Cellular Senescence ; E2F Transcription Factors/antagonists & inhibitors ; Humans ; MicroRNAs/metabolism
Czasopismo naukowe
Tytuł:
Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells.
Autorzy:
Bourdeau V; Institute for Research in Immunology and Cancer and Biochemistry Department, Université de Montréal, C.P. 6128 Succursale Centre Ville, Montréal, QC H3C 3J7, Canada.
Deschênes J
Laperrière D
Aid M
White JH
Mader S
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2008 Jan; Vol. 36 (1), pp. 76-93. Date of Electronic Publication: 2007 Nov 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*/drug effects
Breast Neoplasms/*genetics
Estradiol/*pharmacology
Estrogen Receptor alpha/*metabolism
Estrogens/*pharmacology
Binding Sites ; Cell Line, Tumor ; E2F Transcription Factors/metabolism ; Female ; Gene Expression Profiling ; Humans ; Response Elements ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription.
Autorzy:
Zhang Y; Greenebaum Cancer Center, University of Maryland, Baltimore, BRB 9-029, 655 W. Baltimore Street, Baltimore, MD 21201, USA.
Akinmade D
Hamburger AW
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2005 Oct 27; Vol. 33 (18), pp. 6024-33. Date of Electronic Publication: 2005 Oct 27 (Print Publication: 2005).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Androgen Receptor Antagonists*
Carrier Proteins/*metabolism
Cell Cycle Proteins/*antagonists & inhibitors
DNA-Binding Proteins/*antagonists & inhibitors
Repressor Proteins/*metabolism
Transcription Factors/*antagonists & inhibitors
Adaptor Proteins, Signal Transducing ; Carrier Proteins/chemistry ; Cell Line ; E2F Transcription Factors ; E2F1 Transcription Factor ; Histone Deacetylase 2 ; Histone Deacetylases/metabolism ; Humans ; Promoter Regions, Genetic ; Prostate-Specific Antigen/genetics ; Protein Structure, Tertiary ; RNA-Binding Proteins ; Receptor, ErbB-3/metabolism ; Repressor Proteins/chemistry ; Sin3 Histone Deacetylase and Corepressor Complex ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription.
Autorzy:
Christensen J; Biotech Research & Innovation Centre (BRIC) Fruebjergvej 3, 2100 Copenhagen Ø, Denmark.
Cloos P
Toftegaard U
Klinkenberg D
Bracken AP
Trinh E
Heeran M
Di Stefano L
Helin K
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2005 Sep 22; Vol. 33 (17), pp. 5458-70. Date of Electronic Publication: 2005 Sep 22 (Print Publication: 2005).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
Cell Cycle Proteins/*antagonists & inhibitors
DNA-Binding Proteins/*antagonists & inhibitors
Repressor Proteins/*physiology
Transcription Factors/*antagonists & inhibitors
Amino Acid Sequence ; Animals ; Base Sequence ; Binding Sites ; Cell Cycle ; Cell Cycle Proteins/metabolism ; Cell Line ; Cell Proliferation ; Cloning, Molecular ; Consensus Sequence ; DNA-Binding Proteins/metabolism ; E2F Transcription Factors ; E2F7 Transcription Factor ; Humans ; Mice ; Molecular Sequence Data ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Transcription Factors/metabolism ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells.
Autorzy:
Diaz-Trivino S; Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid Cantoblanco, 28049 Madrid, Spain.
del Mar Castellano M
de la Paz Sanchez M
Ramirez-Parra E
Desvoyes B
Gutierrez C
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2005 Sep 22; Vol. 33 (17), pp. 5404-14. Date of Electronic Publication: 2005 Sep 22 (Print Publication: 2005).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arabidopsis/*genetics
Arabidopsis Proteins/*genetics
Cell Cycle Proteins/*genetics
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*genetics
DNA-Binding Proteins/*metabolism
Transcription Factors/*metabolism
Arabidopsis/growth & development ; Arabidopsis/metabolism ; Arabidopsis Proteins/biosynthesis ; Binding Sites ; Cell Cycle/genetics ; Cell Cycle Proteins/biosynthesis ; Cell Proliferation ; Cells, Cultured ; DNA Replication ; DNA, Complementary/chemistry ; DNA-Binding Proteins/biosynthesis ; E2F Transcription Factors ; Gene Expression Regulation, Plant ; Origin Recognition Complex ; Plant Proteins ; Promoter Regions, Genetic ; Protein Subunits/biosynthesis ; Protein Subunits/genetics
Czasopismo naukowe
Tytuł:
Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library.
Autorzy:
Li Z; Department of Vectorology and Experimental Gene Therapy, University of Rostock Medical School Institute Building, Schillingallee 70, 18057 Rostock, Germany.
Stanelle J
Leurs C
Hanenberg H
Pützer BM
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2005 May 16; Vol. 33 (9), pp. 2813-21. Date of Electronic Publication: 2005 May 16 (Print Publication: 2005).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Library*
Apoptosis/*genetics
Cell Cycle Proteins/*metabolism
DNA, Antisense/*genetics
DNA-Binding Proteins/*metabolism
Retroviridae/*genetics
Tamoxifen/*analogs & derivatives
Transcription Factors/*metabolism
Cell Cycle Proteins/genetics ; Cell Line, Tumor ; Cell Survival ; DNA, Antisense/metabolism ; DNA-Binding Proteins/genetics ; E2F Transcription Factors ; E2F1 Transcription Factor ; Gene Expression Profiling ; Gene Expression Regulation ; Genetic Vectors ; Humans ; Tamoxifen/pharmacology ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł:
Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.
Autorzy:
Tsukada Y; Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 226-8501, Japan. />Tanaka T
Miyazawa K
Kitamura N
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Źródło:
Journal of biochemistry [J Biochem] 2004 Nov; Vol. 136 (5), pp. 701-9.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CDC2-CDC28 Kinases/*metabolism
Carcinoma, Hepatocellular/*metabolism
Cell Cycle/*drug effects
Hepatocyte Growth Factor/*pharmacology
Liver Neoplasms/*metabolism
Mitogens/*pharmacology
Cell Cycle Proteins/biosynthesis ; Cell Cycle Proteins/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin A/biosynthesis ; Cyclin A/metabolism ; Cyclin-Dependent Kinase 2 ; Cyclin-Dependent Kinase Inhibitor p21 ; DNA-Binding Proteins/biosynthesis ; DNA-Binding Proteins/drug effects ; Down-Regulation/drug effects ; E2F Transcription Factors ; E2F1 Transcription Factor ; Flavonoids/pharmacology ; G1 Phase/drug effects ; Hepatocyte Growth Factor/metabolism ; Humans ; Mitogens/metabolism ; Phosphorylation/drug effects ; S Phase/drug effects ; Transcription Factors/biosynthesis ; Transcription Factors/drug effects ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta/pharmacology ; Transforming Growth Factor beta1
Czasopismo naukowe

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