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Wyszukujesz frazę ""ENDOPLASMIC reticulum"" wg kryterium: Temat


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Tytuł :
Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes.
Autorzy :
He Y; Stowers Institute for Medical Research, Kansas City, MO 64110.
Sato S; Stowers Institute for Medical Research, Kansas City, MO 64110.
Tomomori-Sato C; Stowers Institute for Medical Research, Kansas City, MO 64110.
Chen S; Stowers Institute for Medical Research, Kansas City, MO 64110.
Goode ZH; Stowers Institute for Medical Research, Kansas City, MO 64110.
Conaway JW; Stowers Institute for Medical Research, Kansas City, MO 64110; .; Department of Biochemistry and Molecular Biology, Kansas University Medical Center, Kansas City, KS 66160.
Conaway RC; Stowers Institute for Medical Research, Kansas City, MO 64110; .; Department of Biochemistry and Molecular Biology, Kansas University Medical Center, Kansas City, KS 66160.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Gene Expression Regulation*
Activating Transcription Factor 6/*metabolism
Elongin/*metabolism
Mediator Complex/*metabolism
RNA Polymerase II/*metabolism
Activating Transcription Factor 6/genetics ; Animals ; Elongin/genetics ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum/pathology ; HeLa Cells ; Humans ; Mediator Complex/genetics ; Promoter Regions, Genetic ; RNA Polymerase II/genetics ; Rats ; Signal Transduction ; Transcriptional Activation
Czasopismo naukowe
Tytuł :
Multi-level inhibition of coronavirus replication by chemical ER stress.
Autorzy :
Shaban MS; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Müller C; Institute of Medical Virology, Justus Liebig University, Giessen, Germany.
Mayr-Buro C; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Weiser H; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Meier-Soelch J; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Albert BV; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Weber A; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Linne U; Mass spectrometry facility of the Department of Chemistry, Philipps University, Marburg, Germany.
Hain T; Institute of Medical Microbiology, Justus Liebig University, Giessen, Germany.; German Center for Infection Research (DZIF), partner site Giessen-Marburg-Langen, Giessen, Germany.
Babayev I; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany.
Karl N; Institute of Medical Virology, Justus Liebig University, Giessen, Germany.
Hofmann N; Bioinformatics and Systems Biology, Justus Liebig University, Giessen, Germany.
Becker S; Institute of Virology, Philipps University, Marburg, Germany.
Herold S; Department of Internal Medicine II for Pulmonary and Critical Care Medicine and Infectious Diseases, Justus Liebig University, and Institute for Lung Health (ILH), Giessen, Germany.; German Center for Lung Research (DZL) and Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
Schmitz ML; German Center for Lung Research (DZL) and Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.; Institute of Biochemistry, Justus Liebig University, Giessen, Germany.
Ziebuhr J; Institute of Medical Virology, Justus Liebig University, Giessen, Germany. .; German Center for Infection Research (DZIF), partner site Giessen-Marburg-Langen, Giessen, Germany. .
Kracht M; Rudolf Buchheim Institute of Pharmacology, Justus Liebig University, Giessen, Germany. .; German Center for Lung Research (DZL) and Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 20; Vol. 12 (1), pp. 5536. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*/drug effects
Endoplasmic Reticulum Stress*/genetics
SARS-CoV-2/*physiology
Virus Replication/*physiology
Animals ; Autophagy/drug effects ; Bronchi/pathology ; COVID-19/pathology ; COVID-19/virology ; Cell Differentiation/drug effects ; Cell Extracts ; Cell Line ; Cell Survival/drug effects ; Chlorocebus aethiops ; Coronavirus 229E, Human/physiology ; Down-Regulation/drug effects ; Endoplasmic Reticulum-Associated Degradation/drug effects ; Epithelial Cells/drug effects ; Epithelial Cells/virology ; Heat-Shock Proteins/metabolism ; Humans ; Macrolides/pharmacology ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Middle East Respiratory Syndrome Coronavirus/physiology ; Protein Biosynthesis/drug effects ; Proteome/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reproducibility of Results ; SARS-CoV-2/drug effects ; Thapsigargin/pharmacology ; Unfolded Protein Response/drug effects ; Vero Cells ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
SEL1L degradation intermediates stimulate cytosolic aggregation of polyglutamine-expanded protein.
Autorzy :
Hattori T; Department of Molecular and Cellular Biology, Institute for Frontier Medical Sciences, Kyoto University, Japan.
Hanafusa K; Department of Molecular and Cellular Biology, Institute for Frontier Medical Sciences, Kyoto University, Japan.
Wada I; Department of Cell Science, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Japan.
Hosokawa N; Department of Molecular and Cellular Biology, Institute for Frontier Medical Sciences, Kyoto University, Japan.
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Źródło :
The FEBS journal [FEBS J] 2021 Aug; Vol. 288 (15), pp. 4637-4654. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum-Associated Degradation*
Cytosol/*metabolism
Huntingtin Protein/*metabolism
Proteins/*metabolism
Endoplasmic Reticulum/metabolism ; HEK293 Cells ; HeLa Cells ; Hep G2 Cells ; Humans ; Huntingtin Protein/chemistry ; Lectins/metabolism ; Neoplasm Proteins/metabolism ; Peptide Fragments/metabolism ; Protein Binding ; Proteins/chemistry
Czasopismo naukowe
Tytuł :
Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors.
Autorzy :
Sicari D; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.
Centonze FG; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.
Pineau R; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.
Le Reste PJ; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.; Neurosurgery Department, University Hospital of Rennes, Rennes, France.
Negroni L; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; UMR7104, Centre National de la Recherche Scientifique, Illkirch, France.; U1258, Institut National de la Santé et de la Recherche Médicale, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Chat S; CNRS, Institut de Génétique et Développement de Rennes (IGDR), UMR6290, Univ. Rennes, Rennes, France.
Mohtar MA; Edinburgh Cancer Research Centre at the Institute of Genetics and Molecular Medicine, Edinburgh University, Edinburgh, UK.
Thomas D; CNRS, Institut de Génétique et Développement de Rennes (IGDR), UMR6290, Univ. Rennes, Rennes, France.
Gillet R; CNRS, Institut de Génétique et Développement de Rennes (IGDR), UMR6290, Univ. Rennes, Rennes, France.
Hupp T; Edinburgh Cancer Research Centre at the Institute of Genetics and Molecular Medicine, Edinburgh University, Edinburgh, UK.; International Centre for Cancer Vaccine Science, Gdansk, Poland.
Chevet E; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.
Igbaria A; Inserm U1242, University of Rennes, Rennes, France.; Centre de lutte contre le cancer Eugène Marquis, Rennes, France.; Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
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Źródło :
EMBO reports [EMBO Rep] 2021 May 05; Vol. 22 (5), pp. e51412. Date of Electronic Publication: 2021 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum*/metabolism
Endoplasmic Reticulum-Associated Degradation*
Animals ; Cytosol/metabolism ; Endoplasmic Reticulum Stress ; Mice ; Proteins/metabolism
Czasopismo naukowe
Tytuł :
Dual Targeting of Endoplasmic Reticulum by Redox-Deubiquitination Regulation for Cancer Therapy.
Autorzy :
Cai B; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Hou M; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Zhang S; Department of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Xin Z; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Huang J; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Yang J; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Wang Y; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Cai X; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Xie S; Department of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Zhang C; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, People's Republic of China.
Huang Y; Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Jul 30; Vol. 16, pp. 5193-5209. Date of Electronic Publication: 2021 Jul 30 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Endoplasmic Reticulum*/metabolism
Neoplasms*/drug therapy
Neoplasms*/metabolism
Animals ; Apoptosis ; Endoplasmic Reticulum Stress ; Humans ; Mice ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Unfolded Protein Response
Czasopismo naukowe
Tytuł :
Integrated signaling system under endoplasmic reticulum stress in eukaryotic microorganisms.
Autorzy :
Cao T; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Peng B; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Zhou X; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Cai J; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Tang Y; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Luo J; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Xie H; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Zhang J; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China.
Liu S; Department of Clinical Laboratory, The First Affiliated Hospital of University of South China, Hengyang, 421000, Hunan, China. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2021 Jun; Vol. 105 (12), pp. 4805-4818. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Phenomena*
Endoplasmic Reticulum Stress*
Endoplasmic Reticulum/metabolism ; Eukaryota ; Unfolded Protein Response
Czasopismo naukowe
Tytuł :
G-protein-coupled estrogen receptor protects retinal ganglion cells via inhibiting endoplasmic reticulum stress under hyperoxia.
Autorzy :
Li R; Department of Ophthalmology, The First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China.
Wang Y; Department of Ophthalmology, Eye Institute of Shaanxi Province and Xi'an First Hospital, Xi'an, Shaanxi, China.
Chen P; Department of Ophthalmology, Eye Institute of Shaanxi Province and Xi'an First Hospital, Xi'an, Shaanxi, China.
Meng J; School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Zhang H; Department of Ophthalmology, Eye Institute of Shaanxi Province and Xi'an First Hospital, Xi'an, Shaanxi, China.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2021 May; Vol. 236 (5), pp. 3780-3788. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Neuroprotection*
Hyperoxia/*pathology
Receptors, Estrogen/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Retinal Ganglion Cells/*metabolism
Retinal Ganglion Cells/*pathology
Animals ; Apoptosis ; Autophagy ; Calcium/metabolism ; Cell Survival ; Cells, Cultured ; Endoplasmic Reticulum/metabolism ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
The role of sphingolipids in endoplasmic reticulum stress.
Autorzy :
Park WJ; Department of Biochemistry, College of Medicine, Gachon University, Incheon, South Korea.
Park JW; Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul, South Korea.
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Źródło :
FEBS letters [FEBS Lett] 2020 Nov; Vol. 594 (22), pp. 3632-3651. Date of Electronic Publication: 2020 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endoplasmic Reticulum-Associated Degradation*
Endoplasmic Reticulum/*metabolism
Sphingolipids/*metabolism
Cell Communication ; Endoplasmic Reticulum Stress ; Humans ; Mutation ; Signal Transduction
Czasopismo naukowe
Tytuł :
The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells.
Autorzy :
Mehmood AH; Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China. .
Dong B
Lu Y
Song W
Sun Y
Lin W
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Źródło :
Analytical methods : advancing methods and applications [Anal Methods] 2021 May 21; Vol. 13 (19), pp. 2204-2208. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum*
Fluorescent Dyes*
Dithiothreitol ; Endoplasmic Reticulum Stress ; Naphthalimides
Czasopismo naukowe
Tytuł :
Crosstalk between endoplasmic reticulum stress and oxidative stress: Focus on protein disulfide isomerase and endoplasmic reticulum oxidase 1.
Autorzy :
Victor P; Department of Biotechnology, School of Bio-engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603 203, Tamil Nadu, India.
Sarada D; Department of Biotechnology, School of Bio-engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603 203, Tamil Nadu, India.
Ramkumar KM; Department of Biotechnology, School of Bio-engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603 203, Tamil Nadu, India; Life Science Division, SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603 203, Tamil Nadu, India. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Feb 05; Vol. 892, pp. 173749. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Endoplasmic Reticulum Stress*
Oxidative Stress*
Endoplasmic Reticulum/*enzymology
Inflammation/*enzymology
Mitochondria/*enzymology
Oxidoreductases/*metabolism
Protein Disulfide-Isomerases/*metabolism
Animals ; Anti-Inflammatory Agents/therapeutic use ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/pathology ; Enzyme Inhibitors/therapeutic use ; Humans ; Inflammation/drug therapy ; Inflammation/pathology ; Mitochondria/drug effects ; Mitochondria/pathology ; Oxidoreductases/antagonists & inhibitors ; Protein Disulfide-Isomerases/antagonists & inhibitors ; Protein Folding ; Signal Transduction ; Unfolded Protein Response
Czasopismo naukowe
Tytuł :
Ginsenoside Rb1 protects from Staphylococcus aureus-induced oxidative damage and apoptosis through endoplasmic reticulum-stress and death receptor-mediated pathways.
Autorzy :
Shaukat A; National Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan 430070, China.
Shaukat I; Faculty of medicine, University of Lorraine, Nancy, France.
Rajput SA; College of Animal Science, South China Agricultural University Guangzhou, China.
Shukat R; Faculty of Food, Nutrition & Home Sciences, University of Agriculture, Faisalabad, Pakistan.
Hanif S; Department of Physics, University of Gujrat, Gujrat, Pakistan.
Jiang K; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; College of Veterinary Medicine, Yunnan Agricultural University, Kunming, China.
Zhang T; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Akhtar M; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Shaukat I; Department of Physics, University of Agriculture, Faisalabad, Pakistan.
Ma X; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Liu J; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Shaukat S; Department of Plant Breeding and Genetics, University of Agriculture, Faisalabad, Pakistan.
Umar T; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Akhtar M; Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Yang L; National Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan 430070, China. Electronic address: .
Deng G; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Aug; Vol. 219, pp. 112353. Date of Electronic Publication: 2021 May 23.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*pharmacology
Endoplasmic Reticulum Stress/*drug effects
Ginsenosides/*pharmacology
Oxidative Stress/*drug effects
Acute Lung Injury/chemically induced ; Acute Lung Injury/drug therapy ; Acute Lung Injury/genetics ; Animals ; Antioxidants/metabolism ; Apoptosis/drug effects ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Stress/physiology ; Glutathione Peroxidase ; Lung/metabolism ; Malondialdehyde/metabolism ; Mice ; Panax ; Reactive Oxygen Species/metabolism ; Receptors, Death Domain/metabolism ; Retinoblastoma Binding Proteins ; Staphylococcal Infections ; Staphylococcus aureus ; Superoxide Dismutase/metabolism ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł :
The Targeting of Native Proteins to the Endoplasmic Reticulum-Associated Degradation (ERAD) Pathway: An Expanding Repertoire of Regulated Substrates.
Autorzy :
Kumari D; Department of Biological Sciences, University of Pittsburgh, A320 Langley Hall, Fifth & Ruskin Ave, Pittsburgh, PA 15260, USA.
Brodsky JL; Department of Biological Sciences, University of Pittsburgh, A320 Langley Hall, Fifth & Ruskin Ave, Pittsburgh, PA 15260, USA.
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Źródło :
Biomolecules [Biomolecules] 2021 Aug 11; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endoplasmic Reticulum-Associated Degradation*
Endoplasmic Reticulum/*metabolism
Animals ; Mammals/metabolism ; Molecular Chaperones/metabolism ; Protein Folding ; Protein Transport ; Proteolysis ; Ubiquitin/metabolism ; Ubiquitination ; Yeasts/metabolism
Czasopismo naukowe
Tytuł :
Neuronal autophagy controls the axonal endoplasmic reticulum to regulate neurotransmission in healthy neurons.
Autorzy :
Kuijpers M; Department Molecular Pharmacology and Cell Biology, Leibniz-Forschungsinstitut Für Molekulare Pharmakologie (FMP), Berlin, Germany.
Haucke V; Department Molecular Pharmacology and Cell Biology, Leibniz-Forschungsinstitut Für Molekulare Pharmakologie (FMP), Berlin, Germany.; Faculty of Biology, Chemistry, Pharmacy, Freie Universität Berlin, Berlin, Germany.
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Źródło :
Autophagy [Autophagy] 2021 Apr; Vol. 17 (4), pp. 1049-1051. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Autophagy*
Endoplasmic Reticulum Stress*
Endoplasmic Reticulum ; Neurons ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Reactive Oxygen Species Regulate Endoplasmic Reticulum Stress and ER-Mitochondrial Ca Crosstalk to Promote Programmed Necrosis of Rat Nucleus Pulposus Cells under Compression.
Autorzy :
Lin H; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Peng Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Li J; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wang Z; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chen S; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Qing X; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Pu F; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Lei M; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Shao Z; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
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Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2021 Mar 16; Vol. 2021, pp. 8810698. Date of Electronic Publication: 2021 Mar 16 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Endoplasmic Reticulum Stress*
Calcium/*metabolism
Endoplasmic Reticulum/*metabolism
Nucleus Pulposus/*pathology
Reactive Oxygen Species/*metabolism
Animals ; Apoptosis Inducing Factor/metabolism ; Compressive Strength ; Cytoprotection ; Endoplasmic Reticulum/ultrastructure ; HSP70 Heat-Shock Proteins/metabolism ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; Male ; Mitochondria/metabolism ; Mitochondria/ultrastructure ; Mitochondrial Proteins/metabolism ; Necrosis ; Nucleus Pulposus/ultrastructure ; Poly(ADP-ribose) Polymerases/metabolism ; Rats, Sprague-Dawley ; Voltage-Dependent Anion Channel 1/metabolism
Czasopismo naukowe
Tytuł :
Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins.
Autorzy :
Ninagawa S; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan. Electronic address: .
George G; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.
Mori K; Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Mar; Vol. 1865 (3), pp. 129812. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endoplasmic Reticulum-Associated Degradation*
Protein Processing, Post-Translational*
Endoplasmic Reticulum/*metabolism
Glycoproteins/*metabolism
Molecular Chaperones/*metabolism
Protein Disulfide-Isomerases/*metabolism
Animals ; Endoplasmic Reticulum/genetics ; Gene Editing/methods ; Glycoproteins/genetics ; Glycosylation ; Molecular Chaperones/genetics ; Oligosaccharides/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Protein Biosynthesis ; Protein Disulfide-Isomerases/genetics ; Protein Folding ; Protein Transport ; Proteolysis ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł :
[Advance in endoplasmic reticulum-targeting nanodrugs].
Autorzy :
Zhao Y; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Yu Q; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
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Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2021 Feb 25; Vol. 37 (2), pp. 418-428.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Endoplasmic Reticulum*
Neoplasms*/drug therapy
Endoplasmic Reticulum Stress ; Homeostasis ; Humans ; Signal Transduction
Czasopismo naukowe
Tytuł :
Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors.
Autorzy :
Persaud AK; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Nair S; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Rahman MF; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Raj R; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Weadick B; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Nayak D; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
McElroy C; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Shanmugam M; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Knoblaugh S; Depatment of Veterinary Biosciences, College of Veterinary Medicine, Ohio State University, Columbus, OH, 43210, USA.
Cheng X; Division of Medicinal Chemistry & Pharmacognosy, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA.
Govindarajan R; Division of Pharmaceutics & Pharmacology, College of Pharmacy, Ohio State University, Columbus, OH, 43210, USA. .; Translational Therapeutics, Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, OH, 43210, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 23; Vol. 12 (1), pp. 1248. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Bile Acids and Salts/*metabolism
Hematopoietic Stem Cells/*metabolism
Lysosomes/*metabolism
Animals ; Apoptosis/drug effects ; Bile Acids and Salts/blood ; Biological Transport/drug effects ; Bone Marrow Cells/metabolism ; Cell Differentiation/drug effects ; Cell Survival/drug effects ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; Erythroid Cells/drug effects ; Erythroid Cells/metabolism ; Hematopoietic Stem Cell Transplantation ; Hydrogen-Ion Concentration ; Lysosomes/drug effects ; Metabolomics ; Mice ; Nucleoside Transport Proteins/metabolism ; Taurine/metabolism ; Taurochenodeoxycholic Acid/pharmacology
Czasopismo naukowe
Tytuł :
Fine-tuning ER-phagy by post-translational modifications.
Autorzy :
Eldeeb MA; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Zorca CE; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
Ragheb MA; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt.
Rashidi FB; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt.
Salah El-Din DS; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt.
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Źródło :
BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2021 Feb; Vol. 43 (2), pp. e2000212. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Membrane Proteins*/metabolism
Autophagy ; Endoplasmic Reticulum/metabolism ; Humans ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
Naringin Combined with NF-κB Inhibition and Endoplasmic Reticulum Stress Induces Apoptotic Cell Death via Oxidative Stress and the PERK/eIF2α/ATF4/CHOP Axis in HT29 Colon Cancer Cells.
Autorzy :
Albayrak D; Department of Surgery, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.
Doğanlar O; Department of Medical Biology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.
Erdoğan S; Department of Medical Biology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.
Meraklı M; Department of Medical Biology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.
Doğan A; Department of Medical Biology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey.
Turker P; Department of Molecular Genetic Lab, Technology Research and Application Center, Trakya University, 22030, Edirne, Turkey.
Bostancı A; Department of Genetic and Bioengineering, Faculty of Engineering, Trakya University, 22030, Edirne, Turkey.
Doğanlar ZB; Department of Medical Biology, Faculty of Medicine, Trakya University, 22030, Edirne, Turkey. .
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Źródło :
Biochemical genetics [Biochem Genet] 2021 Feb; Vol. 59 (1), pp. 159-184. Date of Electronic Publication: 2020 Sep 26.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Endoplasmic Reticulum Stress*/drug effects
Oxidative Stress*
Signal Transduction*
Flavanones/*pharmacology
NF-kappa B p50 Subunit/*antagonists & inhibitors
Activating Transcription Factor 4/metabolism ; Antioxidants/pharmacology ; Caspases/metabolism ; Cell Line, Tumor ; Cell Survival ; Colonic Neoplasms/drug therapy ; Endoplasmic Reticulum/metabolism ; Eukaryotic Initiation Factor-2/metabolism ; Flavanones/administration & dosage ; HT29 Cells ; Humans ; Mitochondria/metabolism ; Muscle, Smooth, Vascular/cytology ; NF-kappa B p50 Subunit/metabolism ; Nitriles/pharmacology ; Reactive Oxygen Species ; Sulfones/pharmacology ; Transcription Factor CHOP/metabolism ; Tunicamycin/administration & dosage ; eIF-2 Kinase/metabolism
Czasopismo naukowe

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