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Tytuł :
Endothelial Recovery in Bare Metal Stents and Drug-Eluting Stents on a Single-Cell Level.
Autorzy :
Cornelissen A; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).; Department of Cardiology, University Hospital RWTH Aachen, Germany (A.C.).
Guo L; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Fernandez R; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Kelly MC; Single Cell Analysis Facility, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD (M.C.K.).
Janifer C; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Kuntz S; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Sakamoto A; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Jinnouchi H; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Sato Y; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Paek KH; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Kolodgie FD; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Romero ME; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Surve D; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Virmani R; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).
Finn AV; CVPath Institute, Gaithersburg, MD (A.C., L.G., R.F., C.J., S.K., A.S., H.J., Y.S., K.H.P., F.D.K., M.E.R., D.S., R.V., A.V.F.).; University of Maryland, School of Medicine, Baltimore (A.V.F.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Aug; Vol. 41 (8), pp. 2277-2292. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug-Eluting Stents*
Neointima*
Re-Epithelialization*
Single-Cell Analysis*
Endothelial Cells/*ultrastructure
Endovascular Procedures/*instrumentation
Iliac Artery/*ultrastructure
Animals ; Cell Proliferation ; Coronary Vessels/metabolism ; Coronary Vessels/pathology ; Endothelial Cells/metabolism ; Endovascular Procedures/adverse effects ; Gene Expression Profiling ; Gene Expression Regulation ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/ultrastructure ; Humans ; Iliac Artery/metabolism ; Male ; Microscopy, Confocal ; Microscopy, Electron, Scanning ; Models, Animal ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/instrumentation ; RNA-Seq ; Rabbits ; Time Factors ; Transcriptome
Czasopismo naukowe
Tytuł :
Expression of Connexin43 Stimulates Endothelial Angiogenesis Independently of Gap Junctional Communication In Vitro.
Autorzy :
Koepple C; Department for Hand Surgery, Plastic Surgery and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, 67071 Ludwigshafen, Germany.
Zhou Z; Department for Hand Surgery, Plastic Surgery and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, 67071 Ludwigshafen, Germany.
Huber L; Department for Hand Surgery, Plastic Surgery and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, 67071 Ludwigshafen, Germany.
Schulte M; Department for Hand Surgery, Plastic Surgery and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, 67071 Ludwigshafen, Germany.
Schmidt K; Institut für Physiologie, Universität zu Lübeck, 23562 Lübeck, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), 23562 Lübeck, Germany.
Gloe T; Physiology, Institute of Theoretical Medicine, Universität Augsburg, 86159 Augsburg, Germany.
Kneser U; Department for Hand Surgery, Plastic Surgery and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, 67071 Ludwigshafen, Germany.
Schmidt VJ; Department for Plastic Surgery and Breast Surgery, Zealand University Hospital (SUH) Roskilde, Copenhagen University, 4000 Roskilde, Denmark.
de Wit C; Institut für Physiologie, Universität zu Lübeck, 23562 Lübeck, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V. (German Center for Cardiovascular Research), 23562 Lübeck, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 09; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement/*genetics
Cell Proliferation/*genetics
Connexin 43/*metabolism
Endothelial Cells/*metabolism
Gap Junctions/*metabolism
Neovascularization, Physiologic/*genetics
Cell Communication/drug effects ; Cell Communication/genetics ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Connexin 43/genetics ; Connexins/pharmacology ; Endothelial Cells/drug effects ; Gene Expression ; Gene Knockdown Techniques ; Human Umbilical Vein Endothelial Cells ; Humans ; In Vitro Techniques ; Oligopeptides/pharmacology ; RNA, Small Interfering ; Real-Time Polymerase Chain Reaction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Interleukin 22 mitigates endothelial glycocalyx shedding after lipopolysaccharide injury.
Autorzy :
Taghavi S; From the Department of Surgery (S.T., S.A., J.D., O.J.-W.), and Center for Translational Research in Infection and Inflammation (D.P., J.K.), Tulane University School of Medicine, New Orleans, Louisiana.
Abdullah S
Duchesne J
Pociask D
Kolls J
Jackson-Weaver O
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Źródło :
The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2021 Feb 01; Vol. 90 (2), pp. 337-345.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelial Cells*/drug effects
Endothelial Cells*/physiology
Glycocalyx*/immunology
Glycocalyx*/metabolism
Immunoglobulin Fc Fragments/*pharmacology
Interleukins/*metabolism
Lipopolysaccharides/*metabolism
Blood Coagulation/drug effects ; Blood Coagulation/physiology ; Capillary Permeability/drug effects ; Capillary Permeability/physiology ; Down-Regulation ; Human Umbilical Vein Endothelial Cells ; Humans ; Immunoglobulin G ; Matrix Metalloproteinase 2/metabolism ; Protective Agents/pharmacology ; Recombinant Fusion Proteins/pharmacology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Circulating microRNAs Associated With Reversible Cerebral Vasoconstriction Syndrome.
Autorzy :
Chen SP; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; Division of Translational Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Chang YA; Department of Biological Science and Technology, National Chiao Tung University, HsinChu, Taiwan.
Chou CH; Department of Biological Science and Technology, National Chiao Tung University, HsinChu, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Chiao Tung University, HsinChu, Taiwan.
Juan CC; Institute of Physiology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Lee HC; Department and Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Chen LK; Institute of Physiology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Wu PC; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.
Wang YF; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Fuh JL; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Lirng JF; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.; Department of Radiology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
Ducros A; Neurology Department, Montpellier University Hospital, Montpellier, France.; Charles Coulomb Laboratory (L2C), UMR5221CNRS, Montpellier University, Montpellier, France.
Huang HD; Department of Biological Science and Technology, National Chiao Tung University, HsinChu, Taiwan.; School of Life and Health Sciences, The Chinese University of Hong Kong, Shenzhen, China.; Warshel Institute for Computational Biology, The Chinese University of Hong Kong, Shenzhen, China.
Wang SJ; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.; Brain Research Center, National Yang-Ming University, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
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Źródło :
Annals of neurology [Ann Neurol] 2021 Mar; Vol. 89 (3), pp. 459-473. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelial Cells*
Blood-Brain Barrier/*physiopathology
Cerebrovascular Disorders/*genetics
Circulating MicroRNA/*blood
MicroRNAs/*blood
Vasoconstriction/*genetics
Adult ; Capillary Permeability ; Case-Control Studies ; Cerebrovascular Disorders/blood ; Cerebrovascular Disorders/physiopathology ; Circulating MicroRNA/genetics ; Computer Simulation ; Electric Impedance ; Endothelin-1/genetics ; Endothelin-1/metabolism ; Female ; High-Throughput Nucleotide Sequencing ; Human Umbilical Vein Endothelial Cells ; Humans ; In Vitro Techniques ; Male ; Middle Aged ; Migraine Disorders/blood ; Migraine Disorders/genetics ; Migraine Disorders/physiopathology ; Reproducibility of Results ; Sequence Analysis, RNA ; Transforming Growth Factor beta/genetics ; Transforming Growth Factor beta/metabolism ; Vasomotor System/physiopathology
Czasopismo naukowe
Tytuł :
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells.
Autorzy :
Zhang Q; Division of Cardiology, Keenan Research Center for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada.
Wang C; Department of Cardiovascular Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Cannavicci A; Division of Cardiology, Keenan Research Center for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
Faughnan ME; Toronto HHT Centre, St. Michael's Hospital and Li Ka Shing Knowledge Institute, Toronto, Canada; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada.
Kutryk MJB; Division of Cardiology, Keenan Research Center for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address: .
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Źródło :
Translational research : the journal of laboratory and clinical medicine [Transl Res] 2021 Sep; Vol. 235, pp. 129-143. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoglin/*physiology
Endothelial Cells/*physiology
Receptor, Fibroblast Growth Factor, Type 1/*physiology
Receptor, TIE-2/*physiology
Telangiectasia, Hereditary Hemorrhagic/*etiology
Vascular Endothelial Growth Factor A/*physiology
Vascular Endothelial Growth Factor Receptor-2/*physiology
Cells, Cultured ; Extracellular Signal-Regulated MAP Kinases/physiology ; Human Umbilical Vein Endothelial Cells/physiology ; Humans ; Proto-Oncogene Proteins c-akt/physiology
Czasopismo naukowe
Tytuł :
Silencing lncRNA AK136714 reduces endothelial cell damage and inhibits atherosclerosis.
Autorzy :
Bai J; Department of Geriatrics, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Liu J; Department of Nursing, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Fu Z; Department of Scientific Research and Education, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Feng Y; Department of Stomatology, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Wang B; Department of Dynamic electrocardiogram, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Wu W; Department of Breast, The Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
Zhang R; Department of Geriatrics, Affiliated Hospital of Hebei University of Engineering, Handan 056000, Hebei Province, China.
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Źródło :
Aging [Aging (Albany NY)] 2021 May 18; Vol. 13 (10), pp. 14159-14169. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Silencing*
Atherosclerosis/*genetics
Endothelial Cells/*pathology
RNA, Long Noncoding/*metabolism
Animals ; Apoptosis/genetics ; Atherosclerosis/blood ; ELAV-Like Protein 1/metabolism ; Endothelial Cells/metabolism ; Forkhead Box Protein O3/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Inflammation/pathology ; Male ; Mice, Inbred C57BL ; Plaque, Atherosclerotic/blood ; Plaque, Atherosclerotic/genetics ; Plaque, Atherosclerotic/pathology ; Protein Binding ; RNA, Long Noncoding/genetics
Czasopismo naukowe
Tytuł :
Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches.
Autorzy :
Hamzah N; Nutrition & Dietetics Department, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Safuan S; Biomedicine Department, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Wan Ishak WR; Nutrition & Dietetics Department, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 16; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*drug effects
Polyphenols/*pharmacology
Zea mays/*metabolism
Animals ; Antioxidants/pharmacology ; Cell Survival/drug effects ; China ; Cytoprotection/drug effects ; Diabetes Mellitus, Experimental/drug therapy ; Endothelial Cells/metabolism ; Glucose/adverse effects ; Glucose/pharmacology ; Human Umbilical Vein Endothelial Cells/drug effects ; Humans ; Male ; Plant Extracts/pharmacology ; Polyphenols/chemistry ; Rats ; Rats, Sprague-Dawley ; Streptozocin/pharmacology
Czasopismo naukowe
Tytuł :
Major Reservoir for Heparin-Releasable TFPIα (Tissue Factor Pathway Inhibitor α) Is Extracellular Matrix.
Autorzy :
Peterson JA; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Maroney SA; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Martinez ND; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Mast AE; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI (A.E.M.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jun; Vol. 41 (6), pp. 1942-1955. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Endothelial Cells/*metabolism
Extracellular Matrix/*metabolism
Kidney/*blood supply
Lipoproteins/*metabolism
Proteoglycans/*metabolism
Binding Sites ; Binding, Competitive ; Cell Adhesion Molecules/metabolism ; Cell Line ; Endothelial Cells/drug effects ; Extracellular Matrix/drug effects ; Glypicans/metabolism ; Heparin/pharmacology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Protein Binding ; Protein Isoforms ; Syndecan-4/metabolism ; Thrombospondins/metabolism
Czasopismo naukowe
Tytuł :
VEGF-Induced Endothelial Podosomes via ROCK2-Dependent Thrombomodulin Expression Initiate Sprouting Angiogenesis.
Autorzy :
Kuo CH; Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan (C.-H.K., P.-K.C., G.-Y.S., H.-L.W.); College of Medicine and International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan (C.-H.K., G.-H.L., M.-J.T., H.-L.W.)
Huang YH; Institute of Clinical Medicine, National Cheng Kung University, Tainan, Taiwan (Y.-H.H.); Department of Ophthalmology, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan (Y.-H.H.)
Chen PK; Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan (C.-H.K., P.-K.C., G.-Y.S., H.-L.W.); Now with Translational Medicine Laboratory, Rheumatology and Immunology Center, China Medical University Hospital, Taichung, Taiwan (P.-K. C.)
Lee GH; College of Medicine and International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan (C.-H.K., G.-H.L., M.-J.T., H.-L.W.)
Tang MJ; College of Medicine and International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan (C.-H.K., G.-H.L., M.-J.T., H.-L.W.)
Conway EM; Department of Medicine, Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, Canada (E.M.C.).
Shi GY; Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan (C.-H.K., P.-K.C., G.-Y.S., H.-L.W.)
Wu HL; Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan (C.-H.K., P.-K.C., G.-Y.S., H.-L.W.); College of Medicine and International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan, Taiwan (C.-H.K., G.-H.L., M.-J.T., H.-L.W.)
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 May 05; Vol. 41 (5), pp. 1657-1671. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Angiogenesis Inducing Agents/*pharmacology
Endothelial Cells/*drug effects
Neovascularization, Physiologic/*drug effects
Podosomes/*drug effects
Thrombomodulin/*metabolism
Vascular Endothelial Growth Factor A/*pharmacology
rho-Associated Kinases/*metabolism
Actins/metabolism ; Animals ; Cell Movement/drug effects ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Disease Models, Animal ; Endothelial Cells/enzymology ; Female ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/enzymology ; Humans ; Hyperoxia/complications ; Male ; Membrane Microdomains/enzymology ; Mice, Inbred C57BL ; Mice, Knockout ; Podosomes/enzymology ; Retinal Neovascularization/enzymology ; Retinal Neovascularization/etiology ; Retinal Neovascularization/genetics ; Signal Transduction ; Thrombomodulin/genetics ; Wound Healing ; rho-Associated Kinases/genetics
Czasopismo naukowe
Tytuł :
Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation.
Autorzy :
Schubert P; Centre for Innovation, Canadian Blood Services, University of British Columbia, Vancouver, British Columbia, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Culibrk L; Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Culibrk B; Centre for Innovation, Canadian Blood Services, University of British Columbia, Vancouver, British Columbia, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Conway EM; Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.; Departement of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Goodrich RP; Infectious Disease Research Center, Colorado State University, Fort Collins, Colorado, USA.
Devine DV; Centre for Innovation, Canadian Blood Services, University of British Columbia, Vancouver, British Columbia, Canada.; Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło :
Transfusion [Transfusion] 2021 May; Vol. 61 (5), pp. 1551-1561. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*drug effects
Blood Platelets/*radiation effects
Cell-Derived Microparticles/*metabolism
Cytokines/*metabolism
Endothelial Cells/*cytology
Blood Platelets/metabolism ; Blood Preservation ; Blood Safety ; Cell Line ; Cell Movement ; Cell Proliferation ; Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Riboflavin/pharmacology ; Sterilization ; Ultraviolet Rays
Czasopismo naukowe
Tytuł :
RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature.
Autorzy :
Jani VP; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0412, USA.
Asaro R; Department of Structural Engineering, University of California, San Diego, La Jolla, CA 92093-0412, USA.
Oronsky B; EpicentRx Inc., 4445 Eastgate Mall, Suite 200, San Diego, CA 92121, USA.
Cabrales P; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093-0412, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 29; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Azetidines/*pharmacology
Endothelial Cells/*cytology
Erythrocyte Membrane/*drug effects
Nitro Compounds/*pharmacology
Animals ; Antineoplastic Agents/therapeutic use ; Azetidines/therapeutic use ; Cell Adhesion/drug effects ; Cell Hypoxia ; Cysteine/chemistry ; Cytokines/metabolism ; Endothelial Cells/chemistry ; Erythrocyte Aggregation/drug effects ; Erythrocyte Membrane/chemistry ; HT29 Cells/transplantation ; Hep G2 Cells/transplantation ; Human Umbilical Vein Endothelial Cells ; Humans ; Lipopolysaccharides/pharmacology ; Membrane Lipids/biosynthesis ; Mice ; Mice, Nude ; Neoplasms/blood supply ; Neoplasms, Experimental/blood supply ; Neoplasms, Experimental/drug therapy ; Nitro Compounds/therapeutic use ; Phosphatidylserines/biosynthesis ; Receptors, Cell Surface/biosynthesis ; Shear Strength ; Tumor Microenvironment ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells.
Autorzy :
Naresh Amin K; SRM Research Institute and Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, 603 203 Tamilnadu, India.
Rajagru P; Department of Life Sciences, Central University of Tamil Nadu, Tiruvarur 610005, India.
Sarkar K; SRM Research Institute and Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, 603 203 Tamilnadu, India.
Ganesh MR; Interdisciplinary Institute of Indian System of Medicine, SRM Institute of Science and Technology, Kattankulathur, 603 203 Tamilnadu, India.
Suzuki T; Division Cellular and Gene Therapy Products, National Institute of Health Sciences, Setagaya-Ku, Tokyo, Japan.
Ali D; Department of Zoology, College of Science King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Kunka Mohanram R; SRM Research Institute and Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, 603 203 Tamilnadu, India.
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Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2021 Apr 08; Vol. 2021, pp. 2732435. Date of Electronic Publication: 2021 Apr 08 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Aurintricarboxylic Acid/*analogs & derivatives
Endoplasmic Reticulum Stress/*drug effects
Endothelial Cells/*drug effects
NF-E2-Related Factor 2/*metabolism
Aurintricarboxylic Acid/pharmacology ; Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans
Czasopismo naukowe
Tytuł :
Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration.
Autorzy :
Ishikawa J; Laboratory for Organ Regeneration, RIKEN Center for Developmental Biology (CDB) and RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Hyogo, Japan.; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Takeo M; Laboratory for Organ Regeneration, RIKEN Center for Developmental Biology (CDB) and RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Hyogo, Japan.
Iwadate A; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Koya J; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Kihira M; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Oshima M; Laboratory for Organ Regeneration, RIKEN Center for Developmental Biology (CDB) and RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Hyogo, Japan.; Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Suzuki Y; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Taniguchi K; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Kobayashi A; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
Tsuji T; Laboratory for Organ Regeneration, RIKEN Center for Developmental Biology (CDB) and RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Hyogo, Japan. .; Department of Biological Science and Technology, Graduate School of Industrial Science and Technology, Tokyo University of Science, Noda, Chiba, Japan. .
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Źródło :
Communications biology [Commun Biol] 2021 Apr 07; Vol. 4 (1), pp. 409. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Cell Proliferation*
Liver Regeneration*
Capillaries/*pathology
Endothelial Cells/*pathology
Hepatocytes/*pathology
Liver/*blood supply
Liver/*pathology
Animals ; Capillaries/metabolism ; Capillaries/surgery ; Cells, Cultured ; Cytokines/metabolism ; Endothelial Cells/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Hepatectomy ; Hepatocytes/metabolism ; Homeostasis ; Human Umbilical Vein Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Liver/metabolism ; Liver/surgery ; Liver Circulation ; Male ; Mechanotransduction, Cellular ; Mice, Inbred C57BL ; Rats, Wistar ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
MiR-518a-5p Targets GZMB to Extenuate Vascular Endothelial Cell Injury Induced by Hypoxia-Reoxygenation and Thereby Improves Myocardial Ischemia.
Autorzy :
Yang H; Department of Cardiovascular Surgery, The First Affiliated Hospital of Harbin Medical University.
Su J; Department of Cardiovascular Surgery, The First Affiliated Hospital of Harbin Medical University.
Meng W; Department of Cardiovascular Surgery, The First Affiliated Hospital of Harbin Medical University.
Chen X; Department of Ultrasound, The First Affiliated Hospital of Harbin Medical University.
Xu Y; Editorial Department, Journal of Harbin Medical University.
Sun B; Department of Cardiovascular Surgery, The First Affiliated Hospital of Harbin Medical University.
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Źródło :
International heart journal [Int Heart J] 2021 May 29; Vol. 62 (3), pp. 658-665. Date of Electronic Publication: 2021 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*metabolism
Granzymes/*metabolism
MicroRNAs/*metabolism
Myocardial Reperfusion Injury/*metabolism
Human Umbilical Vein Endothelial Cells ; Humans ; Hypoxia/metabolism
Czasopismo naukowe
Tytuł :
FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis.
Autorzy :
Wang C; Clinic Center of Human Gene Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .; Department of Rheumatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
Dai X; Guangdong Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Wu S; Center for Molecular and Translational Medicine, Georgia State University, Atlanta, GA, USA.
Xu W; Clinic Center of Human Gene Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Song P; Center for Molecular and Translational Medicine, Georgia State University, Atlanta, GA, USA.
Huang K; Clinic Center of Human Gene Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
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Źródło :
Nature communications [Nat Commun] 2021 May 10; Vol. 12 (1), pp. 2616. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum/*metabolism
Endothelial Cells/*metabolism
Intracellular Membranes/*metabolism
Membrane Proteins/*metabolism
Mitochondria/*metabolism
Mitochondrial Proteins/*metabolism
Neovascularization, Pathologic/*genetics
Neovascularization, Physiologic/*genetics
Animals ; Calcium/metabolism ; Cytoplasm/metabolism ; Endoplasmic Reticulum/ultrastructure ; Gene Silencing ; Human Umbilical Vein Endothelial Cells ; Humans ; Intracellular Membranes/drug effects ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron, Transmission ; Mitochondria/ultrastructure ; Mitochondrial Proteins/genetics ; Neovascularization, Physiologic/drug effects ; Phosphorylation ; RNA, Small Interfering ; Retina/metabolism ; Serum Response Factor/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Vascular Endothelial Growth Factor Receptor-2/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Kaempferol alleviates human endothelial cell injury through circNOL12/miR-6873-3p/FRS2 axis.
Autorzy :
Li S; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Hao M; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Wu T; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Wang Z; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Wang X; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Zhang J; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China.
Zhang L; Department of Cardiology, Huaihe Hospital of Henan University, Kaifeng, Henan, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111419. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptor Proteins, Signal Transducing/*drug effects
Endothelial Cells/*drug effects
Kaempferols/*pharmacology
Membrane Proteins/*drug effects
MicroRNAs/*drug effects
Nuclear Proteins/*drug effects
RNA-Binding Proteins/*drug effects
Signal Transduction/*drug effects
Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Apoptosis/drug effects ; Female ; Human Umbilical Vein Endothelial Cells ; Humans ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis.
Autorzy :
Wen Y; General Practice Department, The Eighth Affiliated Hospital of Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Chun Y; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Lian ZQ; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Yong ZW; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Lan YM; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Huan L; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Xi CY; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Juan LS; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Qing ZW; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Jia C; Office of Scientific Research and Development, Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
Ji ZH; Cardiovascular Department, The Eighth Affiliated Hospital of Sun Yat‑Sen University, Shenzhen, Guangdong 518000, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Atherosclerosis/*genetics
Carotid Arteries/*metabolism
DNA (Cytosine-5-)-Methyltransferase 1/*genetics
Endothelial Cells/*metabolism
MicroRNAs/*genetics
Plaque, Atherosclerotic/*genetics
RNA, Circular/*genetics
Adult ; Atherosclerosis/metabolism ; Carotid Arteries/pathology ; Cell Movement/genetics ; Cell Proliferation/genetics ; DNA (Cytosine-5-)-Methyltransferase 1/metabolism ; Exosomes/genetics ; Exosomes/metabolism ; Exosomes/ultrastructure ; Female ; Gene Expression Regulation ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Middle Aged ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Plaque, Atherosclerotic/metabolism ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Human endoglin-CD3 bispecific T cell engager antibody induces anti-tumor effect in vivo .
Autorzy :
Zhong L; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.; The First People's Hospital of Changde City, Changde, Hunan 41500, China.
Shi W; Department of Oncology, The First Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China.
Gan L; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Liu X; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Huo Y; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Wu P; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Zhang Z; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Wu T; The First People's Hospital of Changde City, Changde, Hunan 41500, China.
Peng H; The First People's Hospital of Changde City, Changde, Hunan 41500, China.
Huang Y; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Zhao Y; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Yuan Y; National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Guangxi Medical University, Nanning, Guangxi 530021, China. Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi 530021, China.; Department of Laboratory Medicine, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530021, China.
Deng Z; The First People's Hospital of Changde City, Changde, Hunan 41500, China.
Tang H; Department of Oncology, The First Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China.; Department of Scientific Research, The Affiliated Fangchenggang Hospital, Guangxi University of Chinese Medicine, Fangchenggang, Guangxi 538001, China.
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Źródło :
Theranostics [Theranostics] 2021 Apr 19; Vol. 11 (13), pp. 6393-6406. Date of Electronic Publication: 2021 Apr 19 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Bispecific/*therapeutic use
Antineoplastic Agents, Immunological/*therapeutic use
CD3 Complex/*immunology
Endoglin/*immunology
Endothelial Cells/*immunology
T-Lymphocytes/*immunology
A549 Cells ; Amino Acid Sequence ; Angiogenesis Inhibitors/therapeutic use ; Animals ; Antibodies, Bispecific/genetics ; Antibodies, Bispecific/immunology ; Base Sequence ; Cytokines/metabolism ; Cytotoxicity, Immunologic ; Female ; Human Umbilical Vein Endothelial Cells ; Humans ; Lymphocyte Activation ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/immunology ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/immunology ; Th1 Cells/immunology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Endothelial Cell-Mediated Gene Delivery for In Situ Accelerated Endothelialization of a Vascular Graft.
Autorzy :
Zhou J; School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.
Wang M; School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.
Wei T; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Bai L; School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.
Zhao J; School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.
Wang K; Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Feng Y; School of Chemical Engineering and Technology, Tianjin University, Yaguan Road 135, Tianjin 300350, China.; Collaborative Innovation Center of Chemical Science and Chemical Engineering (Tianjin), Tianjin 300350, China.; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Apr 14; Vol. 13 (14), pp. 16097-16105. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Transfer Techniques*
Vascular Grafting*
Endothelial Cells/*metabolism
Animals ; Blotting, Western ; Cell Adhesion ; Cell Proliferation ; Human Umbilical Vein Endothelial Cells ; Humans ; Matrix Metalloproteinases/metabolism ; Microscopy, Electron, Scanning ; Rats ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
The Nucleolar Protein Nucleophosmin Is Physiologically Secreted by Endothelial Cells in Response to Stress Exerting Proangiogenic Activity Both In Vitro and In Vivo.
Autorzy :
Di Carlo A; Tumor Immunology and Immunotherapy Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Beji S; Laboratory of Experimental Immunology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, 00167 Rome, Italy.
Palmerio S; Laboratory of Experimental Immunology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, 00167 Rome, Italy.
Picozza M; Neuroimmunology Unit, IRCSS Fondazione Santa Lucia, 00143 Rome, Italy.
D'Agostino M; Laboratory of Experimental Immunology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, 00167 Rome, Italy.
Petrozza V; Department of Medical Surgical Sciences and Biotechnologies, Sapienza University, 04100 Latina, Italy.
Melchionna R; Tumor Immunology and Immunotherapy Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Germani A; Laboratory of Experimental Immunology, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, 00167 Rome, Italy.
Magenta A; Institute of Translational Pharmacology (IFT), Consiglio Nazionale delle Ricerche (CNR), 00133 Rome, Italy.
De Falco E; Department of Medical Surgical Sciences and Biotechnologies, Sapienza University, 04100 Latina, Italy.; Mediterranea Cardiocentro, 80122 Naples, Italy.
Avitabile D; Department of Scientifico e Sviluppo, IDI Farmaceutici, Via dei Castelli Romani 73/75, 00071 Pomezia, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article
MeSH Terms :
Neovascularization, Pathologic*
Stress, Physiological*
Endothelial Cells/*physiology
Nuclear Proteins/*metabolism
Human Umbilical Vein Endothelial Cells ; Humans
Czasopismo naukowe

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