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Tytuł :
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation.
Autorzy :
Gu SX; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
Tyagi T; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Jain K; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Gu VW; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Lee SH; Division of Cardiovascular Diseases, Center for Biomedical Sciences, National Institute of Health, Cheongju, Chungbuk, Korea.
Hwa JM; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Kwan JM; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Krause DS; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
Lee AI; Section of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
Halene S; Section of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
Martin KA; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Chun HJ; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Hwa J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA. .
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Źródło :
Nature reviews. Cardiology [Nat Rev Cardiol] 2021 Mar; Vol. 18 (3), pp. 194-209. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Blood Coagulation Disorders/*blood
Blood Platelet Disorders/*blood
COVID-19/*blood
Endothelium, Vascular/*physiopathology
Inflammation/*blood
Thrombosis/*blood
Administration, Inhalation ; Anticoagulants/therapeutic use ; Blood Coagulation Disorders/drug therapy ; Blood Coagulation Disorders/etiology ; Blood Coagulation Disorders/physiopathology ; Blood Platelet Disorders/drug therapy ; Blood Platelet Disorders/etiology ; Blood Platelet Disorders/physiopathology ; COVID-19/complications ; COVID-19/drug therapy ; COVID-19/physiopathology ; Endothelium-Dependent Relaxing Factors/therapeutic use ; Epoprostenol/therapeutic use ; Heart Disease Risk Factors ; Humans ; Iloprost/therapeutic use ; Inflammation/etiology ; Inflammation/physiopathology ; Nitric Oxide/therapeutic use ; Platelet Aggregation Inhibitors/therapeutic use ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/blood ; Systemic Inflammatory Response Syndrome/drug therapy ; Systemic Inflammatory Response Syndrome/physiopathology ; Thrombosis/etiology ; Thrombosis/immunology ; Thrombotic Microangiopathies/blood ; Thrombotic Microangiopathies/drug therapy ; Thrombotic Microangiopathies/etiology ; Thrombotic Microangiopathies/physiopathology ; Vascular Diseases/blood ; Vascular Diseases/drug therapy ; Vascular Diseases/etiology ; Vascular Diseases/physiopathology ; Vasodilator Agents/therapeutic use ; Venous Thromboembolism/blood ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; Venous Thromboembolism/physiopathology
SCR Disease Name :
pediatric multisystem inflammatory disease, COVID-19 related
Czasopismo naukowe
Tytuł :
Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19.
Autorzy :
Bernard I; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Limonta D; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Mahal LK; Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.
Hobman TC; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T6G 2E1, Canada.; Department of Cell Biology, University of Alberta, Edmonton, AB T6G 2H7, Canada.; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T6G 2E1, Canada.; Women & Children's Health Research Institute, University of Alberta, Edmonton, AB T6G 1C9, Canada.
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Źródło :
Viruses [Viruses] 2020 Dec 26; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*metabolism
Endothelial Cells/*metabolism
Endothelium/*metabolism
SARS-CoV-2/*immunology
ADAM17 Protein/metabolism ; Angiotensin-Converting Enzyme 2/metabolism ; Antiviral Agents/therapeutic use ; COVID-19/immunology ; Coronavirus ; Coronavirus Infections/metabolism ; Endothelial Cells/immunology ; Endothelium/immunology ; Endothelium/virology ; Endothelium, Vascular/immunology ; Endothelium, Vascular/metabolism ; Humans ; Lung/metabolism ; Thrombosis ; Virus Replication
Czasopismo naukowe
Tytuł :
Changes in endothelial function during educational hospitalization and the contributor to improvement of endothelial function in type 2 diabetes mellitus.
Autorzy :
Goshima Y; First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.; Department of Endocrinology and Metabolism, Toranomon Hospital, Tokyo, Japan.
Okada Y; First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Torimoto K; First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Fujino Y; Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health Japan, Kitakyushu, Japan.
Tanaka Y; First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 21; Vol. 10 (1), pp. 15384. Date of Electronic Publication: 2020 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2/*metabolism
Endothelium, Vascular/*metabolism
Inpatients/*education
Adult ; Aged ; Arteries/physiopathology ; Blood Pressure/physiology ; Endothelial Cells/metabolism ; Endothelial Cells/physiology ; Endothelium/metabolism ; Endothelium/physiology ; Endothelium, Vascular/physiology ; Female ; Glucose/metabolism ; Hospitalization/trends ; Humans ; Hyperemia/physiopathology ; Hypoglycemia/physiopathology ; Lipid Metabolism/physiology ; Male ; Manometry/methods ; Middle Aged ; Risk Factors
Czasopismo naukowe
Tytuł :
A new storm on the horizon in COVID-19: Bradykinin-induced vascular complications.
Autorzy :
McCarthy CG; Center for Hypertension and Personalized Medicine, 3000 Arlington Ave, Toledo, OH 43614-2598, USA; Department of Physiology & Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America. Electronic address: .
Wilczynski S; Cardiovascular Translational Research Center, 6311 Garners Ferry Road, Columbia, SC 29209, United States of America; Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC, United States of America.
Wenceslau CF; Center for Hypertension and Personalized Medicine, 3000 Arlington Ave, Toledo, OH 43614-2598, USA; Department of Physiology & Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States of America.
Webb RC; Cardiovascular Translational Research Center, 6311 Garners Ferry Road, Columbia, SC 29209, United States of America; Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC, United States of America.
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2021 Apr; Vol. 137, pp. 106826. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bradykinin/*metabolism
COVID-19/*complications
Endothelium, Vascular/*metabolism
SARS-CoV-2/*pathogenicity
Vascular Diseases/*metabolism
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; COVID-19/virology ; Endothelium, Vascular/pathology ; Endothelium, Vascular/virology ; Host-Pathogen Interactions ; Humans ; Receptors, Bradykinin/metabolism ; Signal Transduction ; Vascular Diseases/pathology ; Vascular Diseases/virology
Czasopismo naukowe
Tytuł :
Endothelial cells and SARS-CoV-2: An intimate relationship.
Autorzy :
Barbosa LC; Graduate Program in Medicine - Pathological Anatomy, Clementino Fraga Filho Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Brain's Biomedicine Lab, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.
Gonçalves TL; Brain's Biomedicine Lab, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.
de Araujo LP; Brain's Biomedicine Lab, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.
Rosario LVO; Brain's Biomedicine Lab, Paulo Niemeyer State Brain Institute, Rio de Janeiro, Brazil.
Ferrer VP; Graduate Program in Medicine - Pathological Anatomy, Clementino Fraga Filho Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Department of Cellular and Molecular Biology, Institute of Biology, Fluminense Federal University, Niteroi, Brazil. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2021 Apr; Vol. 137, pp. 106829. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*virology
Cardiovascular Diseases/*virology
Endothelium, Vascular/*virology
Inflammation/*virology
SARS-CoV-2/*pathogenicity
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Blood Coagulation ; COVID-19/complications ; COVID-19/therapy ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/therapy ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Host-Pathogen Interactions ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/therapy ; Inflammation Mediators/metabolism ; Neoplasms/metabolism ; Neoplasms/pathology ; Pulmonary Edema/metabolism ; Pulmonary Edema/pathology ; Pulmonary Edema/virology ; Signal Transduction
Czasopismo naukowe
Tytuł :
The implications of COVID-19 infection on the endothelium: A metabolic vascular perspective.
Autorzy :
Dalan R; Department of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
Boehm BO; Department of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
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Źródło :
Diabetes/metabolism research and reviews [Diabetes Metab Res Rev] 2021 Mar; Vol. 37 (3), pp. e3402. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*complications
COVID-19/*pathology
Endothelium, Vascular/*pathology
Metabolic Diseases/*virology
Neovascularization, Pathologic/*virology
Adolescent ; Adult ; Angiotensin-Converting Enzyme 2/physiology ; Basigin/physiology ; Blood Coagulation Disorders/epidemiology ; Blood Coagulation Disorders/pathology ; Blood Coagulation Disorders/physiopathology ; Blood Coagulation Disorders/virology ; COVID-19/epidemiology ; COVID-19/physiopathology ; Chilblains/physiopathology ; Chilblains/virology ; Child ; Comorbidity ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/pathology ; Diabetes Mellitus/physiopathology ; Disease Progression ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Endothelium, Vascular/virology ; Humans ; Metabolic Diseases/epidemiology ; Metabolic Diseases/pathology ; Metabolic Diseases/physiopathology ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; Neovascularization, Pathologic/physiopathology ; Receptors, Cell Surface/physiology ; SARS-CoV-2/pathogenicity ; Serine Endopeptidases/physiology ; Young Adult
Czasopismo naukowe
Tytuł :
Cutaneous Endothelial Dysfunction and Complement Deposition in COVID-19.
Autorzy :
Tammaro A; NESMOS, Dermatology Department, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Adebanjo GAR; NESMOS, Dermatology Department, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Del Nonno F; Pathology Unit, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, Rome, Italy.
Pezzuto A; Cardiovascular-Respiratory Science Department, Sant'Andrea Hospital-Sapienza University of Rome, Rome, Italy.
Ramirez-Estrada S; Critical Care Department, Clínica Corachan, Barcelona, Spain.
Parisella FR; Department of Medicine, Faculty of Medicine, Queensland University, Brisbane, Australia.
Rello J; Centro de Investigación Biomedica en Red de Enfermedades Respirorias (CIBERES), Instituto Salud Carlos III, Madrid, Spain.; Clinical Research/Epidemiology in Pneumonia and Sepsis (CRIPS), Vall d'Hebron Institut of Research (VHIR), Barcelona, Spain.; Clinical Research, CHU Nîmes, Université Montpellier-Nimes, Nîmes, France.
Scarabello A; Dermatology Unit, National Institute of Infectious Diseases Lazzaro Spallanzani-IRCCS, Rome, Italy.
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Źródło :
The American Journal of dermatopathology [Am J Dermatopathol] 2021 Mar 01; Vol. 43 (3), pp. 237-238.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
COVID-19/*virology
Complement System Proteins/*analysis
Endothelium, Vascular/*virology
SARS-CoV-2/*pathogenicity
Skin/*blood supply
Skin/*virology
Skin Diseases, Viral/*virology
Systemic Vasculitis/*virology
Adolescent ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing ; Endothelium, Vascular/immunology ; Endothelium, Vascular/pathology ; Host-Pathogen Interactions ; Humans ; Male ; SARS-CoV-2/immunology ; SARS-CoV-2/isolation & purification ; Skin/immunology ; Skin/pathology ; Skin Diseases, Viral/diagnosis ; Skin Diseases, Viral/immunology ; Systemic Vasculitis/diagnosis ; Systemic Vasculitis/immunology
Raport
Tytuł :
Chloroquine may induce endothelial injury through lysosomal dysfunction and oxidative stress.
Autorzy :
Gregório P; Experimental Nephrology Laboratory, Basic Pathology Department, Universidade Federal do Paraná, Curitiba, PR, Brazil.
da Cunha RS; Experimental Nephrology Laboratory, Basic Pathology Department, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Biagini G; Department of Internal Medicine, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Bosquetti B; Experimental Nephrology Laboratory, Basic Pathology Department, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Budag J; Experimental Nephrology Laboratory, Basic Pathology Department, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Ortiz A; Nephrology and Hypertension, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain; IIS-Fundación Jimenez Diaz UAM, Madrid, Spain.
Sánchez-Niño MD; IIS-Fundación Jimenez Diaz UAM, Madrid, Spain; Department of Pharmacology, School of Medicine, Universidad Autonoma de Madrid, Madrid, Spain.
Barreto FC; Department of Internal Medicine, Division of Nephrology, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Stinghen AEM; Experimental Nephrology Laboratory, Basic Pathology Department, Universidade Federal do Paraná, Curitiba, PR, Brazil. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 01; Vol. 414, pp. 115412. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*drug therapy
Chloroquine/*adverse effects
Endothelial Cells/*drug effects
Endothelium, Vascular/*drug effects
Lysosomes/*drug effects
Oxidative Stress/*drug effects
Cell Survival/drug effects ; Cells, Cultured ; Chloroquine/administration & dosage ; Chloroquine/therapeutic use ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Fabry Disease/chemically induced ; Humans ; Pandemics ; Reactive Oxygen Species ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Tongmai Yangxin pill reduces myocardial No-reflow via endothelium-dependent NO-cGMP signaling by activation of the cAMP/PKA pathway.
Autorzy :
Chen R; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Chen T; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Wang T; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Dai X; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Zhang S; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Jiang D; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Meng K; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Wang Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Geng T; Tianjin Zhongxin Pharmaceutical Group Co., Ltd, Research Institute Branch, Tianjin, 300457, China. Electronic address: .
Xu J; Tianjin Zhongxin Pharmaceutical Group Co., Ltd, Drug Marketing Co., Ltd, Tianjin, 300193, China. Electronic address: .
Zhou K; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
Wang Y; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 01; Vol. 267, pp. 113462. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article
MeSH Terms :
Coronary Vessels/*drug effects
Cyclic AMP/*metabolism
Cyclic AMP-Dependent Protein Kinases/*metabolism
Cyclic GMP/*metabolism
Drugs, Chinese Herbal/*pharmacology
Endothelium, Vascular/*drug effects
Nitric Oxide/*metabolism
No-Reflow Phenomenon/*drug therapy
Vasodilation/*drug effects
Vasodilator Agents/*pharmacology
Animals ; Coronary Circulation/drug effects ; Coronary Vessels/enzymology ; Coronary Vessels/physiopathology ; Disease Models, Animal ; Endothelium, Vascular/enzymology ; Endothelium, Vascular/physiopathology ; Male ; Microcirculation/drug effects ; Myocardium/enzymology ; Myocardium/pathology ; No-Reflow Phenomenon/enzymology ; No-Reflow Phenomenon/pathology ; No-Reflow Phenomenon/physiopathology ; Rats, Sprague-Dawley ; Signal Transduction
Czasopismo naukowe
Tytuł :
MEF2 (Myocyte Enhancer Factor 2) Is Essential for Endothelial Homeostasis and the Atheroprotective Gene Expression Program.
Autorzy :
Lu YW; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
Martino N; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
Gerlach BD; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
Lamar JM; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
Vincent PA; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
Adam AP; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.; Department of Ophthalmology (A.P.A.), Albany Medical College, NY.
Schwarz JJ; Department of Molecular and Cellular Physiology (Y.W.L., N.M., B.D.G., J.M.L., P.A.V., A.P.A., J.J.S.), Albany Medical College, NY.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Mar; Vol. 41 (3), pp. 1105-1123. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Atherosclerosis/*metabolism
Endothelium, Vascular/*metabolism
MEF2 Transcription Factors/*metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Endothelium, Vascular/pathology ; Female ; Gene Expression Regulation ; Homeostasis ; Kruppel-Like Transcription Factors/deficiency ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; MEF2 Transcription Factors/deficiency ; MEF2 Transcription Factors/genetics ; Male ; Mice ; Mice, Knockout ; Receptors, Notch/genetics ; Signal Transduction ; Trans-Activators/metabolism
Czasopismo naukowe
Tytuł :
Human rhinovirus 16 induces antiviral and inflammatory response in the human vascular endothelium.
Autorzy :
Chałubiński M; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Szulc A; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Pawełczyk M; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Gajewski A; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Gawrysiak M; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Likońska A; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
Kowalski ML; Department of Immunology and Allergy, Medical University of Lodz, Lodz, Poland.
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Źródło :
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2021 Mar; Vol. 129 (3), pp. 143-151. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelium, Vascular/*immunology
Picornaviridae Infections/*immunology
Rhinovirus/*immunology
Chemokine CCL5/genetics ; Chemokine CCL5/immunology ; DEAD Box Protein 58/genetics ; DEAD Box Protein 58/immunology ; Endothelium, Vascular/virology ; Human Umbilical Vein Endothelial Cells/immunology ; Human Umbilical Vein Endothelial Cells/virology ; Humans ; Interferon-beta/genetics ; Interferon-beta/immunology ; Picornaviridae Infections/genetics ; Picornaviridae Infections/virology ; Rhinovirus/genetics ; Toll-Like Receptor 3/genetics ; Toll-Like Receptor 3/immunology
Czasopismo naukowe
Tytuł :
From SARS-CoV-2 hematogenous spreading to endothelial dysfunction: clinical-histopathological study of cutaneous signs of COVID-19.
Autorzy :
Patrì A; Department of Clinical Medicine and Surgery, Section of Dermatology and Venereology, University of Naples Federico II, Via Pansini 5, Napoli, Italy. .
Vargas M; Department of Neurosciences, Intensive Care Unit, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Pansini 5, Napoli, Italy.
Buonanno P; Department of Neurosciences, Intensive Care Unit, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Pansini 5, Napoli, Italy.
Annunziata MC; Department of Clinical Medicine and Surgery, Section of Dermatology and Venereology, University of Naples Federico II, Via Pansini 5, Napoli, Italy.
Russo D; Department of Advanced Biomedical Sciences, Pathology Section, University of Naples Federico II, via Pansini 5, Naples, Italy. .
Staibano S; Department of Advanced Biomedical Sciences, Pathology Section, University of Naples Federico II, via Pansini 5, Naples, Italy.
Servillo G; Department of Neurosciences, Intensive Care Unit, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Pansini 5, Napoli, Italy.
Fabbrocini G; Department of Clinical Medicine and Surgery, Section of Dermatology and Venereology, University of Naples Federico II, Via Pansini 5, Napoli, Italy.
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Źródło :
Diagnostic pathology [Diagn Pathol] 2021 Feb 25; Vol. 16 (1), pp. 16. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Case Reports
MeSH Terms :
COVID-19/*pathology
Dermatitis, Exfoliative/*pathology
Endothelium, Vascular/*pathology
Parapsoriasis/*pathology
SARS-CoV-2/*pathogenicity
Skin/*pathology
Aged, 80 and over ; COVID-19/complications ; COVID-19/drug therapy ; COVID-19/virology ; Dermatitis, Exfoliative/drug therapy ; Dermatitis, Exfoliative/virology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/virology ; Fatal Outcome ; Host-Pathogen Interactions ; Humans ; Male ; Parapsoriasis/drug therapy ; Parapsoriasis/virology ; Skin/drug effects ; Skin/virology ; Treatment Outcome
SCR Protocol :
COVID-19 drug treatment
Raport
Tytuł :
Cytomegalovirus endotheliitis with recurrent anterior uveitis and secondary glaucoma misdiagnosed as HLA-B27 uveitis.
Autorzy :
Tendolkar S; Cornea Service, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Murthy SI; Cornea Service, LV Prasad Eye Institute, Hyderabad, Telangana, India .
Bhatia P; Department of Ophthalmology, Mediclinic Welcare Hospital, Dubai, UAE.
Senthil S; VST Center for Glaucoma, LV Prasad Eye Institute, Hyderabad, Telangana, India.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Feb 19; Vol. 14 (2). Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Diagnostic Errors*
Cytomegalovirus Infections/*complications
Cytomegalovirus Infections/*diagnosis
Endothelium, Corneal/*virology
Glaucoma/*complications
Uveitis/*complications
Antiviral Agents/therapeutic use ; Cytomegalovirus/isolation & purification ; Cytomegalovirus Infections/drug therapy ; Endothelium, Corneal/drug effects ; Endothelium, Corneal/surgery ; HLA-B27 Antigen ; Humans ; Male ; Middle Aged ; Uveitis/diagnosis ; Uveitis/surgery ; Valganciclovir/therapeutic use
Czasopismo naukowe
Tytuł :
β 1- and β 2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation.
Autorzy :
Ou Z; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Dolmatova E; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Lassègue B; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Griendling KK; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2021 Feb 01; Vol. 320 (2), pp. H734-H739. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Capillary Permeability*
Chemotaxis, Leukocyte*
CD18 Antigens/*metabolism
Endothelium, Vascular/*metabolism
Inflammation/*metabolism
Inflammation Mediators/*metabolism
Integrin beta1/*metabolism
Leukocytes/*metabolism
Animals ; Cell Adhesion ; Cell Communication ; Endothelium, Vascular/immunology ; Endothelium, Vascular/physiopathology ; Humans ; Inflammation/immunology ; Inflammation/physiopathology ; Leukocyte Rolling ; Leukocytes/immunology ; Signal Transduction ; Transendothelial and Transepithelial Migration
Czasopismo naukowe
Tytuł :
Endothelium-independent vasorelaxant effect of Asphodelus tenuifolius Cav. via inhibition of myosin light chain kinase activity in the porcine coronary artery.
Autorzy :
Younis W; Laboratory of Cardiovascular Research and Integrative Pharmacology, College of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, United Kingdom.
Alamgeer; Laboratory of Cardiovascular Research and Integrative Pharmacology, College of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan; Punjab University College of Pharmacy University of the Punjab, Lahore, Pakistan. Electronic address: .
Schini-Kerth VB; UMR 1260 INSERM Nanomédecine Régénérative Faculté de Pharmacie, Université de Strasbourg, Illkirch, France.
Junior AG; Laboratory of Electrophysiology and Cardiovascular Pharmacology, Federal University of Grande Dourados (UFGD), P.O. Box 533, 79.804-970, Dourados, MS, Brazil.
Nocchi SR; Laboratório de Produtos Naturais e Espectrometria de Massas (LaPNEM), Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazil.
Silva DB; Laboratório de Produtos Naturais e Espectrometria de Massas (LaPNEM), Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazil.
Roberts RE; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, United Kingdom. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 06; Vol. 269, pp. 113693. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article
MeSH Terms :
Xanthorrhoeaceae*
Coronary Vessels/*drug effects
Endothelium, Vascular/*drug effects
Myosin-Light-Chain Kinase/*antagonists & inhibitors
Plant Extracts/*pharmacology
Vasodilator Agents/*pharmacology
Animals ; Coronary Vessels/enzymology ; Dose-Response Relationship, Drug ; Endothelium, Vascular/enzymology ; Enzyme Inhibitors/isolation & purification ; Enzyme Inhibitors/pharmacology ; Organ Culture Techniques ; Plant Extracts/isolation & purification ; Swine ; Vasodilator Agents/isolation & purification
Czasopismo naukowe
Tytuł :
Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation.
Autorzy :
Chioh FW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Fong SW; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
Young BE; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.
Wu KX; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Siau A; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Krishnan S; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, ANA Futura, Campus Flemingsberg, Stockholm, Sweden.
Chan YH; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Carissimo G; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Teo LL; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Gao F; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Tan RS; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Zhong L; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Koh AS; National Heart Centre Singapore, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.
Tan SY; Department of Infectious Diseases, Changi General Hospital, Singapore, Singapore.
Tambyah PA; Department of Medicine, National University Hospital, Singapore, Singapore.
Renia L; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Ng LF; A*STAR ID Labs, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Lye DC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Cheung C; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.
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Źródło :
ELife [Elife] 2021 Mar 23; Vol. 10. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocyte Activation*
COVID-19/*complications
Cardiovascular Diseases/*etiology
Endothelium, Vascular/*pathology
Adult ; Aged ; COVID-19/immunology ; COVID-19/pathology ; Cardiovascular Diseases/immunology ; Cardiovascular Diseases/pathology ; Cytokines/immunology ; Endothelial Cells/immunology ; Endothelial Cells/pathology ; Endothelium, Vascular/immunology ; Female ; Humans ; Male ; Middle Aged ; Risk Factors
Czasopismo naukowe
Tytuł :
Safeguarding the Vasculature: Redundant Transcriptional Machinery Ensures Endothelial Protection.
Autorzy :
Sweet DR; Department of Medicine, Case Cardiovascular Research Institute (D.R.S., M.K.J.), Case Western Reserve University, Cleveland, OH.; Department of Pathology (D.R.S.), Case Western Reserve University, Cleveland, OH.; Department of Medicine, Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, OH (D.R.S., M.K.J.).
Jain MK; Department of Medicine, Case Cardiovascular Research Institute (D.R.S., M.K.J.), Case Western Reserve University, Cleveland, OH.; Department of Medicine, Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, OH (D.R.S., M.K.J.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Mar; Vol. 41 (3), pp. 1124-1126. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Editorial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Atherosclerosis*
Endothelium, Vascular*
Gene Expression ; Homeostasis ; Humans ; MEF2 Transcription Factors
Raport
Tytuł :
Taurine treatment reverses protein malnutrition-induced endothelial dysfunction of the pancreatic vasculature: The role of hydrogen sulfide.
Autorzy :
Guizoni DM; Laboratory of Vascular Biology, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Freitas IN; Laboratory of Vascular Biology, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Victorio JA; Laboratory of Vascular Biology, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Possebom IR; Laboratory of Vascular Biology, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Araujo TR; Obesity and Comorbidities Research Center-OCRC, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Carneiro EM; Obesity and Comorbidities Research Center-OCRC, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Davel AP; Laboratory of Vascular Biology, Institute of Biology, Department of Structural and Functional Biology, University of Campinas-UNICAMP, Campinas, SP, Brazil. Electronic address: .
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Źródło :
Metabolism: clinical and experimental [Metabolism] 2021 Mar; Vol. 116, pp. 154701. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelium, Vascular/*drug effects
Hydrogen Sulfide/*pharmacology
Malnutrition/*complications
Pancreas/*drug effects
Protein Deficiency/*complications
Taurine/*therapeutic use
Animals ; Blood Pressure/drug effects ; Dietary Proteins/administration & dosage ; Endothelium, Vascular/physiopathology ; Malnutrition/drug therapy ; Malnutrition/physiopathology ; Mice ; Mice, Inbred C57BL ; Pancreas/blood supply ; Pancreas/physiopathology ; Protein Deficiency/drug therapy ; Protein Deficiency/physiopathology ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
The Preparation of Chicken Ex Ovo Embryos and Chorioallantoic Membrane Vessels as In Vivo Model for Contrast-Enhanced Ultrasound Imaging and Microbubble-Mediated Drug Delivery Studies.
Autorzy :
Meijlink B; Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam; .
Skachkov I; Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam.
van der Steen AFW; Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam; Laboratory of Acoustical Wavefield Imaging, Faculty of Applied Sciences, Delft University of Technology.
de Jong N; Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam; Laboratory of Acoustical Wavefield Imaging, Faculty of Applied Sciences, Delft University of Technology.
Kooiman K; Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2021 Feb 09 (168). Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Contrast Media*
Drug Delivery Systems*
Microbubbles*
Chorioallantoic Membrane/*chemistry
Endothelium, Vascular/*diagnostic imaging
Propidium/*administration & dosage
Ultrasonography/*methods
Animals ; Chick Embryo ; Chickens ; Coloring Agents/administration & dosage ; Egg Shell/chemistry ; Endothelium, Vascular/drug effects
Czasopismo naukowe
Tytuł :
Obesity-induced cognitive impairment in older adults: a microvascular perspective.
Autorzy :
Balasubramanian P; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Kiss T; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Theoretical Medicine Doctoral School, Departments of Medical Physics and Informatics & Cell Biology and Molecular Medicine, University of Szeged, Szeged, Hungary.
Tarantini S; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine, Department of Public Health, Semmelweis University, Budapest, Hungary.; Department of Health Promotion Sciences, the Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Nyúl-Tóth Á; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Institute of Biophysics, Biological Research Centre, Szeged, Hungary.
Ahire C; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Yabluchanskiy A; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Csipo T; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine, Department of Public Health, Semmelweis University, Budapest, Hungary.; International Training Program in Geroscience, Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Lipecz A; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine, Department of Public Health, Semmelweis University, Budapest, Hungary.
Tabak A; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine, Department of Public Health, Semmelweis University, Budapest, Hungary.; Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.; Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Institoris A; Hotchkiss Brain Institute, Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Csiszar A; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Theoretical Medicine Doctoral School, Departments of Medical Physics and Informatics & Cell Biology and Molecular Medicine, University of Szeged, Szeged, Hungary.
Ungvari Z; Vascular Cognitive Impairment and Neurodegeneration Program, Department of Biochemistry and Molecular Biology, Center for Geroscience and Healthy Brain Aging/Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.; International Training Program in Geroscience, Theoretical Medicine Doctoral School, Departments of Medical Physics and Informatics & Cell Biology and Molecular Medicine, University of Szeged, Szeged, Hungary.; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine, Department of Public Health, Semmelweis University, Budapest, Hungary.; Department of Health Promotion Sciences, the Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2021 Feb 01; Vol. 320 (2), pp. H740-H761. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cognition*
Neurovascular Coupling*
Blood-Brain Barrier/*physiopathology
Cognitive Dysfunction/*physiopathology
Endothelium, Vascular/*physiopathology
Microvessels/*physiopathology
Obesity/*physiopathology
Age Factors ; Aged ; Animals ; Blood-Brain Barrier/metabolism ; Cognitive Aging ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/prevention & control ; Cognitive Dysfunction/psychology ; Endothelium, Vascular/metabolism ; Female ; Humans ; Male ; Microcirculation ; Microvessels/metabolism ; Obesity/epidemiology ; Obesity/psychology ; Obesity/therapy ; Risk Assessment ; Risk Factors
Czasopismo naukowe

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