- Tytuł:
- ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer.
- Autorzy:
- Źródło:
- International journal of molecular sciences [Int J Mol Sci] 2024 Feb 17; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 17.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathologyets -Domain Protein Elk-1*
Gefitinib*/pharmacology
Gefitinib*/therapeutic use
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Tyrosine Kinase Inhibitors*/pharmacology
Tyrosine Kinase Inhibitors*/therapeutic use
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/metabolism ; Mice, Nude ; Ribosomal Protein S6 Kinases ; RNA, Small Interfering/pharmacology ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe