Autor: "Egan, Josephine M." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Cross-sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments.
Autorzy:: Moaddel R; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Ubaida-Mohien C; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Tanaka T; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Tian Q; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Candia J; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Moore AZ; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Lovett J; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Fantoni G; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Shehadeh N; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Turek L; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Collingham V; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Kaileh M; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Chia CW; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Sen R; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Egan JM; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Ferrucci L; Biomedical Research Centre, National Institute on Aging, NIH, Baltimore, Maryland, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e13902. Date of Electronic Publication: 2023 Jun 23.
Typ publikacji:: Journal Article
MeSH Terms:: Aging*
Metabolomics*
Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Biomarkers/metabolism ; Cellular Senescence

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Skocz do pozycji: 2.

Tytuł:: Novel Hominid-Specific IAPP Isoforms: Potential Biomarkers of Early Alzheimer's Disease and Inhibitors of Amyloid Formation.
Autorzy:: Liu QR; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.
Zhu M; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.
Chen Q; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.
Mustapic M; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.
Kapogiannis D; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.
Egan JM; Laboratory of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD 21224, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2023 Jan 13; Vol. 13 (1). Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Alzheimer Disease*/genetics
Hominidae*
Animals ; Humans ; Islet Amyloid Polypeptide/genetics ; Proteomics ; Amyloidogenic Proteins ; Amyloid ; Amyloid beta-Peptides ; Protein Isoforms/genetics ; Biomarkers

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Skocz do pozycji: 3.

Tytuł:: Empagliflozin Induced Ketosis, Upregulated IGF-1/Insulin Receptors and the Canonical Insulin Signaling Pathway in Neurons, and Decreased the Excitatory Neurotransmitter Glutamate in the Brain of Non-Diabetics.
Autorzy:: Avgerinos KI; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Mullins RJ; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Vreones M; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Mustapic M; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Chen Q; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Melvin D; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Kapogiannis D; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Egan JM; Laboratory of Clinical Investigation, Intramural Program, National Institute on Aging, NIH, Baltimore, MD 21224, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Oct 25; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:: Clinical Trial; Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Alzheimer Disease*/metabolism
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Ketosis*/metabolism
Sodium-Glucose Transporter 2 Inhibitors*/pharmacology
Female ; Humans ; Middle Aged ; Blood Glucose/metabolism ; Brain/metabolism ; Glutamic Acid/metabolism ; Insulin/metabolism ; Insulin, Regular, Human/metabolism ; Insulin-Like Growth Factor I/metabolism ; Neurons/metabolism ; Neurotransmitter Agents/metabolism ; Placenta Growth Factor/metabolism ; Placenta Growth Factor/pharmacology ; Receptor, Insulin/metabolism ; Signal Transduction

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Skocz do pozycji: 4.

Tytuł:: Age-associated expression of p21and p53 during human wound healing.
Autorzy:: Chia CW; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Sherman-Baust CA; Laboratory of Molecular Biology & Immunology, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Larson SA; Laboratory of Molecular Biology & Immunology, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Pandey R; Laboratory of Molecular Biology & Immunology, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Withers R; Laboratory of Molecular Biology & Immunology, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Karikkineth AC; Clinical Research Core & Biorepository, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Zukley LM; Clinical Research Core & Biorepository, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Campisi J; Buck Institute for Research on Aging, Novato, CA, USA.; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Egan JM; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Sen R; Laboratory of Molecular Biology & Immunology, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Ferrucci L; Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2021 May; Vol. 20 (5), pp. e13354. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Wound Healing*
Aging/*metabolism
Cyclin-Dependent Kinase Inhibitor p21/*metabolism
Tumor Suppressor Protein p53/*metabolism
Adult ; Aged ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Female ; Humans ; Male ; Pilot Projects ; Skin/metabolism

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Skocz do pozycji: 5.

Tytuł:: Incretins in obesity and diabetes.
Autorzy:: Chia CW; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
Egan JM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.; Pokaż więcej
Źródło:: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2020 Feb; Vol. 1461 (1), pp. 104-126. Date of Electronic Publication: 2019 Aug 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:: Diabetes Mellitus, Type 2/*metabolism
Incretins/*metabolism
Obesity/*metabolism
Animals ; Endocannabinoids/metabolism ; Gastrointestinal Microbiome ; Guidelines as Topic ; Humans

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Skocz do pozycji: 6.

Tytuł:: Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity.
Autorzy:: Kim Y; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.
Rouse M; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.
González-Mariscal I; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.
Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.
O'Connell JF; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, 251 Bayview Blvd, Suite 100, Baltimore, MD 21224 USA.; Pokaż więcej
Źródło:: Nutrition & metabolism [Nutr Metab (Lond)] 2019 Jul 25; Vol. 16, pp. 48. Date of Electronic Publication: 2019 Jul 25 (Print Publication: 2019).
Typ publikacji:: Journal Article

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Skocz do pozycji: 7.

Tytuł:: Correction to: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.
Autorzy:: Hishimoto A; Department of Psychiatry, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-Cho, Chuo-Ku, Kobe, 650-0017, Japan.
Pletnikova O; Departments of Pathology, Neuropathology Division, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21205, USA.
Lang DL; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA.
Troncoso JC; Departments of Pathology, Neuropathology Division, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21205, USA.
Egan JM; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA.
Liu QR; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA. .; Pokaż więcej
Źródło:: Alzheimer's research & therapy [Alzheimers Res Ther] 2019 May 07; Vol. 11 (1), pp. 39. Date of Electronic Publication: 2019 May 07.
Typ publikacji:: Published Erratum

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Skocz do pozycji: 8.

Tytuł:: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.
Autorzy:: Hishimoto A; Department of Psychiatry, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-Cho, Chuo-Ku, Kobe, 650-0017, Japan.
Pletnikova O; Departments of Pathology, Neuropathology Division, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21205, USA.
Lang DL; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA.
Troncoso JC; Departments of Pathology, Neuropathology Division, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21205, USA.
Egan JM; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA.
Liu QR; Lab of Clinical Investigation, NIA-NIH, 251 Bayview Blvd, Baltimore, MD, 21224, USA. .; Pokaż więcej
Źródło:: Alzheimer's research & therapy [Alzheimers Res Ther] 2019 Mar 21; Vol. 11 (1), pp. 28. Date of Electronic Publication: 2019 Mar 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: Alzheimer Disease/*genetics
Alzheimer Disease/*metabolism
Encephalitis/*metabolism
Nerve Tissue Proteins/*genetics
Nerve Tissue Proteins/*metabolism
Neurons/*metabolism
Prefrontal Cortex/*metabolism
Aged ; Aged, 80 and over ; Alzheimer Disease/complications ; Apolipoproteins E/genetics ; Encephalitis/complications ; Female ; Haplotypes ; Humans ; Male ; Polymorphism, Single Nucleotide ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; RNA, Messenger/metabolism

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Skocz do pozycji: 9.

Tytuł:: Chronic Low-Calorie Sweetener Use and Risk of Abdominal Obesity among Older Adults: A Cohort Study.
Autorzy:: Chia CW; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Shardell M; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Tanaka T; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Liu DD; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Gravenstein KS; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Simonsick EM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Egan JM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Ferrucci L; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Nov 23; Vol. 11 (11), pp. e0167241. Date of Electronic Publication: 2016 Nov 23 (Print Publication: 2016).
Typ publikacji:: Clinical Trial; Journal Article; Multicenter Study; Observational Study
MeSH Terms:: Body Mass Index*
Obesity, Abdominal*/epidemiology
Obesity, Abdominal*/physiopathology
Energy Intake/*drug effects
Sweetening Agents/*administration & dosage
Adult ; Age Factors ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Risk Factors ; Sex Factors

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Skocz do pozycji: 10.

Tytuł:: Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism.
Autorzy:: González-Mariscal I; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Krzysik-Walker SM; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Doyle ME; Department of Medicine, Johns Hopkins Medical Institutes, Baltimore, MD 21224, USA.
Liu QR; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Cimbro R; Department of Medicine, Johns Hopkins Medical Institutes, Baltimore, MD 21224, USA.
Santa-Cruz Calvo S; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Ghosh S; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Cieśla Ł; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Moaddel R; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Carlson OD; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Witek RP; Thermo Fisher Scientific, 7300 Governor's Way, Frederick, MD 21704 USA.
O'Connell JF; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Sep 19; Vol. 6, pp. 33302. Date of Electronic Publication: 2016 Sep 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Glucose/*metabolism
Hepatocytes/*metabolism
Insulin-Secreting Cells/*metabolism
Receptor, Cannabinoid, CB1/*metabolism
Amino Acid Sequence ; Animals ; CHO Cells ; Cells, Cultured ; Cricetinae ; Cricetulus ; Gene Expression Profiling/methods ; Hepatocytes/drug effects ; Humans ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/drug effects ; Metabolic Diseases/metabolism ; Piperidines/metabolism ; Piperidines/pharmacology ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Pyrazoles/metabolism ; Pyrazoles/pharmacology ; Receptor, Cannabinoid, CB1/genetics ; Rimonabant ; Sequence Homology, Amino Acid ; Sulfonamides/metabolism ; Sulfonamides/pharmacology

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Skocz do pozycji: 11.

Tytuł:: Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells.
Autorzy:: Kim J; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.
Lee KJ; Department of Convergence Medicine, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Korea.
Kim JS; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.
Rho JG; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.
Shin JJ; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.
Song WK; Department of Life Science, Bio Imaging and Cell Dynamics Research Center, Gwangju Institute of Science and Technology, Gwangju, 61005, South Korea.
Lee EK; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul, 06591, South Korea.
Egan JM; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, United States of America.
Kim W; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, South Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Mar 11; Vol. 11 (3), pp. e0150981. Date of Electronic Publication: 2016 Mar 11 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cannabinoids/*pharmacology
Cyclin D2/*genetics
Gene Expression Regulation/*drug effects
Insulin-Secreting Cells/*metabolism
Proto-Oncogene Proteins c-bcl-2/*genetics
Receptor, Cannabinoid, CB1/*physiology
Animals ; Apoptosis/genetics ; Cell Cycle Checkpoints/drug effects ; Cell Line ; Cell Proliferation/genetics ; Cyclin D2/metabolism ; Flow Cytometry ; Insulin-Secreting Cells/drug effects ; Mice ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Receptor, Cannabinoid, CB1/metabolism

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Skocz do pozycji: 12.

Tytuł:: Does GLP-1 suppress its own basal secretion?
Autorzy:: Elahi D; a ICON Early Phase Services, LLC , San Antonio , TX , USA .
Ruff DA; a ICON Early Phase Services, LLC , San Antonio , TX , USA .
Carlson OD; b Diabetes Section, National Institute on Aging , Baltimore , MD , USA .
Meneilly GS; c Department of Medicine , University of British Columbia School of Medicine , Vancouver , BC , Canada , and.
Habener JF; d Department of Medicine , Harvard Medical School and Massachusetts General Hospital , Boston , MA , USA.
Egan JM; b Diabetes Section, National Institute on Aging , Baltimore , MD , USA .; Pokaż więcej
Źródło:: Endocrine research [Endocr Res] 2016; Vol. 41 (1), pp. 16-20. Date of Electronic Publication: 2015 Jul 17.
Typ publikacji:: Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Feedback, Physiological/*drug effects
Glucagon-Like Peptide 1/*analogs & derivatives
Glucagon-Like Peptide 1/*metabolism
Peptide Fragments/*pharmacology
Peptides/*pharmacology
Adult ; Basal Metabolism/drug effects ; Blood Glucose/metabolism ; Female ; Glucagon/blood ; Glucagon-Like Peptide 1/pharmacology ; Humans ; Insulin/blood ; Male ; Obesity/metabolism ; Thinness/metabolism

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Skocz do pozycji: 13.

Tytuł:: Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds.
Autorzy:: Yang H; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
Cong WN
Yoon JS
Egan JM; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2015 Feb; Vol. 4 (2), pp. 245-52. Date of Electronic Publication: 2014 Oct 30.
Typ publikacji:: Journal Article
MeSH Terms:: Anilides/*adverse effects
Gene Expression Regulation/*drug effects
Pyridines/*adverse effects
Taste/*drug effects
Taste Buds/*drug effects
Anilides/administration & dosage ; Animals ; Body Weight/drug effects ; Cell Count ; Cell Size/drug effects ; Hedgehog Proteins/antagonists & inhibitors ; Kruppel-Like Transcription Factors ; Mice ; Mice, Inbred C57BL ; Pyridines/administration & dosage ; Signal Transduction/drug effects ; Taste Buds/physiology ; Zinc Finger Protein GLI1

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Skocz do pozycji: 14.

Tytuł:: A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Autorzy:: Manning AK; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Hivert MF
Scott RA
Grimsby JL
Bouatia-Naji N
Chen H
Rybin D
Liu CT
Bielak LF
Prokopenko I
Amin N
Barnes D
Cadby G
Hottenga JJ
Ingelsson E
Jackson AU
Johnson T
Kanoni S
Ladenvall C
Lagou V
Lahti J
Lecoeur C
Liu Y
Martinez-Larrad MT
Montasser ME
Navarro P
Perry JR
Rasmussen-Torvik LJ
Salo P
Sattar N
Shungin D
Strawbridge RJ
Tanaka T
van Duijn CM
An P
de Andrade M
Andrews JS
Aspelund T
Atalay M
Aulchenko Y
Balkau B
Bandinelli S
Beckmann JS
Beilby JP
Bellis C
Bergman RN
Blangero J
Boban M
Boehnke M
Boerwinkle E
Bonnycastle LL
Boomsma DI
Borecki IB
Böttcher Y
Bouchard C
Brunner E
Budimir D
Campbell H
Carlson O
Chines PS
Clarke R
Collins FS
Corbatón-Anchuelo A
Couper D
de Faire U
Dedoussis GV
Deloukas P
Dimitriou M
Egan JM
Eiriksdottir G
Erdos MR
Eriksson JG
Eury E
Ferrucci L
Ford I
Forouhi NG
Fox CS
Franzosi MG
Franks PW
Frayling TM
Froguel P
Galan P
de Geus E
Gigante B
Glazer NL
Goel A
Groop L
Gudnason V
Hallmans G
Hamsten A
Hansson O
Harris TB
Hayward C
Heath S
Hercberg S
Hicks AA
Hingorani A
Hofman A
Hui J
Hung J
Jarvelin MR
Jhun MA
Johnson PC
Jukema JW
Jula A
Kao WH
Kaprio J
Kardia SL
Keinanen-Kiukaanniemi S
Kivimaki M
Kolcic I
Kovacs P
Kumari M
Kuusisto J
Kyvik KO
Laakso M
Lakka T
Lannfelt L
Lathrop GM
Launer LJ
Leander K
Li G
Lind L
Lindstrom J
Lobbens S
Loos RJ
Luan J
Lyssenko V
Mägi R
Magnusson PK
Marmot M
Meneton P
Mohlke KL
Mooser V
Morken MA
Miljkovic I
Narisu N
O'Connell J
Ong KK
Oostra BA
Palmer LJ
Palotie A
Pankow JS
Peden JF
Pedersen NL
Pehlic M
Peltonen L
Penninx B
Pericic M
Perola M
Perusse L
Peyser PA
Polasek O
Pramstaller PP
Province MA
Räikkönen K
Rauramaa R
Rehnberg E
Rice K
Rotter JI
Rudan I
Ruokonen A
Saaristo T
Sabater-Lleal M
Salomaa V
Savage DB
Saxena R
Schwarz P
Seedorf U
Sennblad B
Serrano-Rios M
Shuldiner AR
Sijbrands EJ
Siscovick DS
Smit JH
Small KS
Smith NL
Smith AV
Stančáková A
Stirrups K
Stumvoll M
Sun YV
Swift AJ
Tönjes A
Tuomilehto J
Trompet S
Uitterlinden AG
Uusitupa M
Vikström M
Vitart V
Vohl MC
Voight BF
Vollenweider P
Waeber G
Waterworth DM
Watkins H
Wheeler E
Widen E
Wild SH
Willems SM
Willemsen G
Wilson JF
Witteman JC
Wright AF
Yaghootkar H
Zelenika D
Zemunik T
Zgaga L
Wareham NJ
McCarthy MI
Barroso I
Watanabe RM
Florez JC
Dupuis J
Meigs JB
Langenberg C; Pokaż więcej
Corporate Authors:: DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Multiple Tissue Human Expression Resource (MUTHER) Consortium
Źródło:: Nature genetics [Nat Genet] 2012 May 13; Vol. 44 (6), pp. 659-69. Date of Electronic Publication: 2012 May 13.
Typ publikacji:: Journal Article; Meta-Analysis
MeSH Terms:: Body Mass Index*
Polymorphism, Single Nucleotide*
Blood Glucose/*metabolism
Insulin/*metabolism
Insulin Resistance/*genetics
Cholesterol, HDL/metabolism ; Diabetes Mellitus, Type 2/genetics ; Genome-Wide Association Study ; Humans

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Skocz do pozycji: 15.

Tytuł:: A genome-wide association search for type 2 diabetes genes in African Americans.
Autorzy:: Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America. />McDonough CW
Hicks PJ
Roh BH
Wing MR
An SS
Hester JM
Cooke JN
Bostrom MA
Rudock ME
Talbert ME
Lewis JP
Ferrara A
Lu L
Ziegler JT
Sale MM
Divers J
Shriner D
Adeyemo A
Rotimi CN
Ng MC
Langefeld CD
Freedman BI
Bowden DW
Voight BF
Scott LJ
Steinthorsdottir V
Morris AP
Dina C
Welch RP
Zeggini E
Huth C
Aulchenko YS
Thorleifsson G
McCulloch LJ
Ferreira T
Grallert H
Amin N
Wu G
Willer CJ
Raychaudhuri S
McCarroll SA
Langenberg C
Hofmann OM
Dupuis J
Qi L
Segrè AV
van Hoek M
Navarro P
Ardlie K
Balkau B
Benediktsson R
Bennett AJ
Blagieva R
Boerwinkle E
Bonnycastle LL
Boström KB
Bravenboer B
Bumpstead S
Burtt NP
Charpentier G
Chines PS
Cornelis M
Couper DJ
Crawford G
Doney AS
Elliott KS
Elliott AL
Erdos MR
Fox CS
Franklin CS
Ganser M
Gieger C
Grarup N
Green T
Griffin S
Groves CJ
Guiducci C
Hadjadj S
Hassanali N
Herder C
Isomaa B
Jackson AU
Johnson PR
Jørgensen T
Kao WH
Klopp N
Kong A
Kraft P
Kuusisto J
Lauritzen T
Li M
Lieverse A
Lindgren CM
Lyssenko V
Marre M
Meitinger T
Midthjell K
Morken MA
Narisu N
Nilsson P
Owen KR
Payne F
Perry JR
Petersen AK
Platou C
Proença C
Prokopenko I
Rathmann W
Rayner NW
Robertson NR
Rocheleau G
Roden M
Sampson MJ
Saxena R
Shields BM
Shrader P
Sigurdsson G
Sparsø T
Strassburger K
Stringham HM
Sun Q
Swift AJ
Thorand B
Tichet J
Tuomi T
van Dam RM
van Haeften TW
van Herpt T
van Vliet-Ostaptchouk JV
Walters GB
Weedon MN
Wijmenga C
Witteman J
Bergman RN
Cauchi S
Collins FS
Gloyn AL
Gyllensten U
Hansen T
Hide WA
Hitman GA
Hofman A
Hunter DJ
Hveem K
Laakso M
Mohlke KL
Morris AD
Palmer CN
Pramstaller PP
Rudan I
Sijbrands E
Stein LD
Tuomilehto J
Uitterlinden A
Walker M
Wareham NJ
Watanabe RM
Abecasis GR
Boehm BO
Campbell H
Daly MJ
Hattersley AT
Hu FB
Meigs JB
Pankow JS
Pedersen O
Wichmann HE
Barroso I
Florez JC
Frayling TM
Groop L
Sladek R
Thorsteinsdottir U
Wilson JF
Illig T
Froguel P
van Duijn CM
Stefansson K
Altshuler D
Boehnke M
McCarthy MI
Soranzo N
Wheeler E
Glazer NL
Bouatia-Naji N
Mägi R
Randall J
Johnson T
Elliott P
Rybin D
Henneman P
Dehghan A
Hottenga JJ
Song K
Goel A
Egan JM
Lajunen T
Doney A
Kanoni S
Cavalcanti-Proença C
Kumari M
Timpson NJ
Zabena C
Ingelsson E
An P
O'Connell J
Luan J
Elliott A
McCarroll SA
Roccasecca RM
Pattou F
Sethupathy P
Ariyurek Y
Barter P
Beilby JP
Ben-Shlomo Y
Bergmann S
Bochud M
Bonnefond A
Borch-Johnsen K
Böttcher Y
Brunner E
Bumpstead SJ
Chen YD
Chines P
Clarke R
Coin LJ
Cooper MN
Crisponi L
Day IN
de Geus EJ
Delplanque J
Fedson AC
Fischer-Rosinsky A
Forouhi NG
Frants R
Franzosi MG
Galan P
Goodarzi MO
Graessler J
Grundy S
Gwilliam R
Hallmans G
Hammond N
Han X
Hartikainen AL
Hayward C
Heath SC
Hercberg S
Hicks AA
Hillman DR
Hingorani AD
Hui J
Hung J
Jula A
Kaakinen M
Kaprio J
Kesaniemi YA
Kivimaki M
Knight B
Koskinen S
Kovacs P
Kyvik KO
Lathrop GM
Lawlor DA
Le Bacquer O
Lecoeur C
Li Y
Mahley R
Mangino M
Manning AK
Martínez-Larrad MT
McAteer JB
McPherson R
Meisinger C
Melzer D
Meyre D
Mitchell BD
Mukherjee S
Naitza S
Neville MJ
Oostra BA
Orrù M
Pakyz R
Paolisso G
Pattaro C
Pearson D
Peden JF
Pedersen NL
Perola M
Pfeiffer AF
Pichler I
Polasek O
Posthuma D
Potter SC
Pouta A
Province MA
Psaty BM
Rayner NW
Rice K
Ripatti S
Rivadeneira F
Rolandsson O
Sandbaek A
Sandhu M
Sanna S
Sayer AA
Scheet P
Seedorf U
Sharp SJ
Shields B
Sijbrands EJ
Silveira A
Simpson L
Singleton A
Smith NL
Sovio U
Swift A
Syddall H
Syvänen AC
Tanaka T
Tönjes A
Uitterlinden AG
van Dijk KW
Varma D
Visvikis-Siest S
Vitart V
Vogelzangs N
Waeber G
Wagner PJ
Walley A
Ward KL
Watkins H
Wild SH
Willemsen G
Witteman JC
Yarnell JW
Zelenika D
Zethelius B
Zhai G
Zhao JH
Zillikens MC
Borecki IB
Loos RJ
Meneton P
Magnusson PK
Nathan DM
Williams GH
Silander K
Salomaa V
Smith GD
Bornstein SR
Schwarz P
Spranger J
Karpe F
Shuldiner AR
Cooper C
Dedoussis GV
Serrano-Ríos M
Lind L
Palmer LJ
Franks PW
Ebrahim S
Marmot M
Kao WH
Pramstaller PP
Wright AF
Stumvoll M
Hamsten A
Buchanan TA
Valle TT
Rotter JI
Siscovick DS
Penninx BW
Boomsma DI
Deloukas P
Spector TD
Ferrucci L
Cao A
Scuteri A
Schlessinger D
Uda M
Ruokonen A
Jarvelin MR
Waterworth DM
Vollenweider P
Peltonen L
Mooser V
Sladek R; Pokaż więcej
Corporate Authors:: DIAGRAM Consortium
MAGIC Investigators
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (1), pp. e29202. Date of Electronic Publication: 2012 Jan 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Genome-Wide Association Study*
Black or African American/*genetics
Diabetes Mellitus, Type 2/*ethnology
Diabetes Mellitus, Type 2/*genetics
Adult ; Aged ; Case-Control Studies ; Cohort Studies ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Meta-Analysis as Topic ; Middle Aged ; Polymorphism, Single Nucleotide ; Validation Studies as Topic

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Tytuł:: Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Autorzy:: Dastani Z; Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.
Hivert MF
Timpson N
Perry JR
Yuan X
Scott RA
Henneman P
Heid IM
Kizer JR
Lyytikäinen LP
Fuchsberger C
Tanaka T
Morris AP
Small K
Isaacs A
Beekman M
Coassin S
Lohman K
Qi L
Kanoni S
Pankow JS
Uh HW
Wu Y
Bidulescu A
Rasmussen-Torvik LJ
Greenwood CM
Ladouceur M
Grimsby J
Manning AK
Liu CT
Kooner J
Mooser VE
Vollenweider P
Kapur KA
Chambers J
Wareham NJ
Langenberg C
Frants R
Willems-Vandijk K
Oostra BA
Willems SM
Lamina C
Winkler TW
Psaty BM
Tracy RP
Brody J
Chen I
Viikari J
Kähönen M
Pramstaller PP
Evans DM
St Pourcain B
Sattar N
Wood AR
Bandinelli S
Carlson OD
Egan JM
Böhringer S
van Heemst D
Kedenko L
Kristiansson K
Nuotio ML
Loo BM
Harris T
Garcia M
Kanaya A
Haun M
Klopp N
Wichmann HE
Deloukas P
Katsareli E
Couper DJ
Duncan BB
Kloppenburg M
Adair LS
Borja JB
Wilson JG
Musani S
Guo X
Johnson T
Semple R
Teslovich TM
Allison MA
Redline S
Buxbaum SG
Mohlke KL
Meulenbelt I
Ballantyne CM
Dedoussis GV
Hu FB
Liu Y
Paulweber B
Spector TD
Slagboom PE
Ferrucci L
Jula A
Perola M
Raitakari O
Florez JC
Salomaa V
Eriksson JG
Frayling TM
Hicks AA
Lehtimäki T
Smith GD
Siscovick DS
Kronenberg F
van Duijn C
Loos RJ
Waterworth DM
Meigs JB
Dupuis J
Richards JB
Voight BF
Scott LJ
Steinthorsdottir V
Dina C
Welch RP
Zeggini E
Huth C
Aulchenko YS
Thorleifsson G
McCulloch LJ
Ferreira T
Grallert H
Amin N
Wu G
Willer CJ
Raychaudhuri S
McCarroll SA
Hofmann OM
Segrè AV
van Hoek M
Navarro P
Ardlie K
Balkau B
Benediktsson R
Bennett AJ
Blagieva R
Boerwinkle E
Bonnycastle LL
Boström KB
Bravenboer B
Bumpstead S
Burtt NP
Charpentier G
Chines PS
Cornelis M
Crawford G
Doney AS
Elliott KS
Elliott AL
Erdos MR
Fox CS
Franklin CS
Ganser M
Gieger C
Grarup N
Green T
Griffin S
Groves CJ
Guiducci C
Hadjadj S
Hassanali N
Herder C
Isomaa B
Jackson AU
Johnson PR
Jørgensen T
Kao WH
Kong A
Kraft P
Kuusisto J
Lauritzen T
Li M
Lieverse A
Lindgren CM
Lyssenko V
Marre M
Meitinger T
Midthjell K
Morken MA
Narisu N
Nilsson P
Owen KR
Payne F
Petersen AK
Platou C
Proença C
Prokopenko I
Rathmann W
Rayner NW
Robertson NR
Rocheleau G
Roden M
Sampson MJ
Saxena R
Shields BM
Shrader P
Sigurdsson G
Sparsø T
Strassburger K
Stringham HM
Sun Q
Swift AJ
Thorand B
Tichet J
Tuomi T
van Dam RM
van Haeften TW
van Herpt T
van Vliet-Ostaptchouk JV
Walters GB
Weedon MN
Wijmenga C
Witteman J
Bergman RN
Cauchi S
Collins FS
Gloyn AL
Gyllensten U
Hansen T
Hide WA
Hitman GA
Hofman A
Hunter DJ
Hveem K
Laakso M
Morris AD
Palmer CN
Rudan I
Sijbrands E
Stein LD
Tuomilehto J
Uitterlinden A
Walker M
Watanabe RM
Abecasis GR
Boehm BO
Campbell H
Daly MJ
Hattersley AT
Pedersen O
Barroso I
Groop L
Sladek R
Thorsteinsdottir U
Wilson JF
Illig T
Froguel P
van Duijn CM
Stefansson K
Altshuler D
Boehnke M
McCarthy MI
Soranzo N
Wheeler E
Glazer NL
Bouatia-Naji N
Mägi R
Randall J
Elliott P
Rybin D
Dehghan A
Hottenga JJ
Song K
Goel A
Lajunen T
Doney A
Cavalcanti-Proença C
Kumari M
Timpson NJ
Zabena C
Ingelsson E
An P
O'Connell J
Luan J
Elliott A
McCarroll SA
Roccasecca RM
Pattou F
Sethupathy P
Ariyurek Y
Barter P
Beilby JP
Ben-Shlomo Y
Bergmann S
Bochud M
Bonnefond A
Borch-Johnsen K
Böttcher Y
Brunner E
Bumpstead SJ
Chen YD
Chines P
Clarke R
Coin LJ
Cooper MN
Crisponi L
Day IN
de Geus EJ
Delplanque J
Fedson AC
Fischer-Rosinsky A
Forouhi NG
Franzosi MG
Galan P
Goodarzi MO
Graessler J
Grundy S
Gwilliam R
Hallmans G
Hammond N
Han X
Hartikainen AL
Hayward C
Heath SC
Hercberg S
Hillman DR
Hingorani AD
Hui J
Hung J
Kaakinen M
Kaprio J
Kesaniemi YA
Kivimaki M
Knight B
Koskinen S
Kovacs P
Kyvik KO
Lathrop GM
Lawlor DA
Le Bacquer O
Lecoeur C
Li Y
Mahley R
Mangino M
Martínez-Larrad MT
McAteer JB
McPherson R
Meisinger C
Melzer D
Meyre D
Mitchell BD
Mukherjee S
Naitza S
Neville MJ
Orrù M
Pakyz R
Paolisso G
Pattaro C
Pearson D
Peden JF
Pedersen NL
Pfeiffer AF
Pichler I
Polasek O
Posthuma D
Potter SC
Pouta A
Province MA
Rayner NW
Rice K
Ripatti S
Rivadeneira F
Rolandsson O
Sandbaek A
Sandhu M
Sanna S
Sayer AA
Scheet P
Seedorf U
Sharp SJ
Shields B
Sigurðsson G
Sijbrands EJ
Silveira A
Simpson L
Singleton A
Smith NL
Sovio U
Swift A
Syddall H
Syvänen AC
Tönjes A
Uitterlinden AG
van Dijk KW
Varma D
Visvikis-Siest S
Vitart V
Vogelzangs N
Waeber G
Wagner PJ
Walley A
Ward KL
Watkins H
Wild SH
Willemsen G
Witteman JC
Yarnell JW
Zelenika D
Zethelius B
Zhai G
Zhao JH
Zillikens MC
Borecki IB
Meneton P
Magnusson PK
Nathan DM
Williams GH
Silander K
Bornstein SR
Schwarz P
Spranger J
Karpe F
Shuldiner AR
Cooper C
Serrano-Ríos M
Lind L
Palmer LJ
Hu FB 1st
Franks PW
Ebrahim S
Marmot M
Kao WH
Pramstaller PP
Wright AF
Stumvoll M
Hamsten A
Buchanan TA
Valle TT
Rotter JI
Penninx BW
Boomsma DI
Cao A
Scuteri A
Schlessinger D
Uda M
Ruokonen A
Jarvelin MR
Peltonen L
Mooser V
Sladek R
Musunuru K
Smith AV
Edmondson AC
Stylianou IM
Koseki M
Pirruccello JP
Chasman DI
Johansen CT
Fouchier SW
Peloso GM
Barbalic M
Ricketts SL
Bis JC
Feitosa MF
Orho-Melander M
Melander O
Li X
Li M
Cho YS
Go MJ
Kim YJ
Lee JY
Park T
Kim K
Sim X
Ong RT
Croteau-Chonka DC
Lange LA
Smith JD
Ziegler A
Zhang W
Zee RY
Whitfield JB
Thompson JR
Surakka I
Spector TD
Smit JH
Sinisalo J
Scott J
Saharinen J
Sabatti C
Rose LM
Roberts R
Rieder M
Parker AN
Pare G
O'Donnell CJ
Nieminen MS
Nickerson DA
Montgomery GW
McArdle W
Masson D
Martin NG
Marroni F
Lucas G
Luben R
Lokki ML
Lettre G
Launer LJ
Lakatta EG
Laaksonen R
Kyvik KO
König IR
Khaw KT
Kaplan LM
Johansson Å
Janssens AC
Igl W
Hovingh GK
Hengstenberg C
Havulinna AS
Hastie ND
Harris TB
Haritunians T
Hall AS
Groop LC
Gonzalez E
Freimer NB
Erdmann J
Ejebe KG
Döring A
Dominiczak AF
Demissie S
Deloukas P
de Faire U
Crawford G
Chen YD
Caulfield MJ
Boekholdt SM
Assimes TL
Quertermous T
Seielstad M
Wong TY
Tai ES
Feranil AB
Kuzawa CW
Taylor HA Jr
Gabriel SB
Holm H
Gudnason V
Krauss RM
Ordovas JM
Munroe PB
Kooner JS
Tall AR
Hegele RA
Kastelein JJ
Schadt EE
Strachan DP
Reilly MP
Samani NJ
Schunkert H
Cupples LA
Sandhu MS
Ridker PM
Rader DJ
Kathiresan S; Pokaż więcej
Corporate Authors:: DIAGRAM+ Consortium
MAGIC Consortium
GLGC Investigators
MuTHER Consortium
DIAGRAM Consortium
GIANT Consortium
Global B Pgen Consortium
Procardis Consortium
MAGIC investigators
GLGC Consortium
Źródło:: PLoS genetics [PLoS Genet] 2012; Vol. 8 (3), pp. e1002607. Date of Electronic Publication: 2012 Mar 29.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome-Wide Association Study*
Adiponectin/*blood
Diabetes Mellitus, Type 2/*genetics
Adiponectin/genetics ; Black or African American ; Asian People ; Cholesterol, HDL/genetics ; Female ; Gene Expression ; Genetic Predisposition to Disease ; Glucose Tolerance Test ; Humans ; Insulin Resistance/genetics ; Male ; Metabolic Networks and Pathways ; Polymorphism, Single Nucleotide ; Waist-Hip Ratio ; White People

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Tytuł:: Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes.
Autorzy:: Di Pasquale G; Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America.
Dicembrini I
Raimondi L
Pagano C
Egan JM
Cozzi A
Cinci L
Loreto A
Manni ME
Berretti S
Morelli A
Zheng C
Michael DG
Maggi M
Vettor R
Chiorini JA
Mannucci E
Rotella CM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2012; Vol. 7 (7), pp. e40074. Date of Electronic Publication: 2012 Jul 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dependovirus/*genetics
Diabetes Mellitus, Type 2/*therapy
Genetic Therapy/*methods
Obesity/*therapy
Peptides/*genetics
Salivary Glands/*metabolism
Venoms/*genetics
Animals ; Blood Glucose/analysis ; Diabetes Mellitus, Type 2/blood ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Exenatide ; Gene Expression ; Genetic Vectors ; Glucagon-Like Peptide-1 Receptor ; Glucose Tolerance Test ; Humans ; Male ; Mice ; Obesity/blood ; Obesity/etiology ; Peptides/blood ; Peptides/metabolism ; Rats ; Rats, Zucker ; Receptors, Glucagon/agonists ; Venoms/blood ; Venoms/metabolism ; Weight Gain

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Tytuł:: Insulin and glucagon regulate pancreatic α-cell proliferation.
Autorzy:: Liu Z; National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.
Kim W
Chen Z
Shin YK
Carlson OD
Fiori JL
Xin L
Napora JK
Short R
Odetunde JO
Lao Q
Egan JM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2011 Jan 25; Vol. 6 (1), pp. e16096. Date of Electronic Publication: 2011 Jan 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Cell Proliferation*
Glucagon/*physiology
Glucagon-Secreting Cells/*cytology
Insulin/*pharmacology
Animals ; Diabetes Mellitus, Type 2/pathology ; Dose-Response Relationship, Drug ; Glucagon/blood ; Hypertrophy/etiology ; Insulin/therapeutic use ; Mice ; Mice, Inbred Strains

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Tytuł:: Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants.
Autorzy:: Shin YK; National Institute on Aging/National Institutes of Health, Baltimore, Maryland, United States of America.
Martin B
Kim W
White CM
Ji S
Sun Y
Smith RG
Sévigny J
Tschöp MH
Maudsley S
Egan JM; Pokaż więcej
Źródło:: PloS one [PLoS One] 2010 Sep 14; Vol. 5 (9), pp. e12729. Date of Electronic Publication: 2010 Sep 14.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Taste Perception*
Citric Acid/*metabolism
Epithelial Cells/*metabolism
Ghrelin/*metabolism
Receptors, Ghrelin/*deficiency
Sodium Chloride/*metabolism
Taste Buds/*metabolism
Animals ; Cells, Cultured ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Proprotein Convertase 1/metabolism ; Receptors, Ghrelin/genetics ; Signal Transduction ; Taste Buds/cytology

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Tytuł:: Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging.
Autorzy:: Golden E; Cellular and Molecular Neurosciences Section, National Institute on Aging Intramural Research Program, Baltimore, Maryland, United States of America.
Emiliano A
Maudsley S
Windham BG
Carlson OD
Egan JM
Driscoll I
Ferrucci L
Martin B
Mattson MP; Pokaż więcej
Źródło:: PloS one [PLoS One] 2010 Apr 09; Vol. 5 (4), pp. e10099. Date of Electronic Publication: 2010 Apr 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: Brain-Derived Neurotrophic Factor/*blood
Cardiovascular Diseases/*diagnosis
Metabolic Syndrome/*diagnosis
Age Factors ; Aged ; Biomarkers/blood ; Cardiovascular Diseases/blood ; Female ; Humans ; Male ; Metabolic Syndrome/blood ; Middle Aged ; Risk Factors ; Sex Factors

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