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Tytuł:
The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms.
Autorzy:
Mehta D (AUTHOR)
Quast C (AUTHOR)
Fasching PA (AUTHOR)
Seifert A (AUTHOR)
Voigt F (AUTHOR)
Beckmann MW (AUTHOR)
Faschingbauer F (AUTHOR)
Burger P (AUTHOR)
Ekici AB (AUTHOR)
Kornhuber J (AUTHOR)
Binder EB (AUTHOR)
Goecke TW (AUTHOR)
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Źródło:
Journal of Affective Disorders. Feb2012, Vol. 136 Issue 3, p1192-1197. 6p.
Czasopismo naukowe
Tytuł:
Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
Autorzy:
Yazar V; German Center for Neurodegenerative Diseases (DZNE), 89081, Ulm, Baden-Wüerttemberg, Germany.
Kühlwein JK; Department of Neurology, University Clinic, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Baden-Wüerttemberg, Germany.
Knehr A; Department of Neurology, University Clinic, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Baden-Wüerttemberg, Germany.
Grozdanov V; Department of Neurology, University Clinic, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Baden-Wüerttemberg, Germany.
Ekici AB; Institute of Human Genetics, University Clinic Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Bavaria, Germany.
Ludolph AC; German Center for Neurodegenerative Diseases (DZNE), 89081, Ulm, Baden-Wüerttemberg, Germany.; Department of Neurology, University Clinic, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Baden-Wüerttemberg, Germany.
Danzer KM; German Center for Neurodegenerative Diseases (DZNE), 89081, Ulm, Baden-Wüerttemberg, Germany. .; Department of Neurology, University Clinic, University of Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Baden-Wüerttemberg, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 25; Vol. 13 (1), pp. 12019. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Amyotrophic Lateral Sclerosis*/metabolism
Animals ; Mice ; Leukocytes, Mononuclear/metabolism ; Mice, Transgenic ; Mutation ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/genetics
SCR Disease Name:
Amyotrophic lateral sclerosis 1
Czasopismo naukowe
Tytuł:
Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells.
Autorzy:
Enders M; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.; Institute of Anatomy and Cell Biology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
Weier A; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.; Institute of Anatomy and Cell Biology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
Chunder R; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
An Y; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Bremm F; Department of Biology, Animal Physiology, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Feigenspan A; Department of Biology, Animal Physiology, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Buettner C; Institute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
Ekici AB; Institute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
Mingardo E; Institute of Anatomy and Cell Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Odermatt B; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
Kuerten S; Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115 Bonn, Germany.; Institute of Anatomy and Cell Biology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 13; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Oligodendrocyte Precursor Cells*/metabolism
Encephalomyelitis, Autoimmune, Experimental*/metabolism
Multiple Sclerosis*/metabolism
MicroRNAs*/metabolism
Animals ; Mice ; Nimodipine/pharmacology ; Calcium Channel Blockers/pharmacology ; Zebrafish/genetics ; Myelin Sheath/metabolism ; Oligodendroglia/metabolism ; Calcium Channels, L-Type/metabolism ; Cell Differentiation
Czasopismo naukowe
Tytuł:
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Autorzy:
Mueller SH; Institute of Health Informatics, University College London, London, UK.
Lai AG; Institute of Health Informatics, University College London, London, UK.
Valkovskaya M; Division of Psychiatry, University College London, London, UK.
Michailidou K; Biostatistics Unit, The Cyprus Institute of Neurology and Genetics, 2371, Nicosia, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology and Genetics, 2371, Nicosia, Cyprus.; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
Lush M; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
Abu-Ful Z; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 35254, Haifa, Israel.
Ahearn TU; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
Andrulis IL; Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Anton-Culver H; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, 92617, USA.
Antonenkova NN; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040, Minsk, Belarus.
Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Aronson KJ; Department of Public Health Sciences, and Cancer Research Institute, Queen's University, Kingston, ON, K7L 3N6, Canada.
Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden.
Baert T; Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000, Louvain, Belgium.
Freeman LEB; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Benitez J; Biomedical Network On Rare Diseases (CIBERER), 28029, Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029, Madrid, Spain.
Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, 450054, Russia.
Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, 00290, Helsinki, Finland.; Department of Oncology, Örebro University Hospital, 70185, Örebro, Sweden.
Bogdanova NV; N.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040, Minsk, Belarus.; Department of Radiation Oncology, Hannover Medical School, 30625, Hannover, Germany.; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany.
Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Bonanni B; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT), 69120, Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Brucker SY; Department of Gynecology and Obstetrics, University of Tübingen, 72076, Tübingen, Germany.
Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, 84112, USA.
Castelao JE; Oncology and Genetics Unit, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, 36312, Vigo, Spain.
Chan TL; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, China.; Department of Molecular Pathology, Hong Kong Sanatorium and Hospital, Hong Kong, China.
Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, 03080, Korea.; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul, 03080, Korea.
Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, NY, 10032, USA.
Colonna SV; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, 84112, USA.
Cornelissen S; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.
Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA.
Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Dörk T; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany.
Dossus L; Nutrition and Metabolism Section, International Agency for Research On Cancer (IARC-WHO), 69372, Lyon, France.
Dwek M; School of Life Sciences, University of Westminster, London, W1W 6UW, UK.
Eccles DM; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK.
Ekici AB; Institute of Human Genetics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107, Leipzig, Germany.; LIFE - Leipzig Research Centre for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
Evans DG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.
Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, 90095, USA.
Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.
Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730, Herlev, Denmark.
Gago-Dominguez M; Genomic Medicine Group, International Cancer Genetics and Epidemiology Group, Fundación Pœblica Galega de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, 15706, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.
Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, 20032, China.
García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
García-Sáenz JA; Medical Oncology Department, Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), 28040, Madrid, Spain.
Genkinger J; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA.
Gentry-Maharaj A; Institute of Clinical Trials and Methodology, University College London, London, WC1V 6LJ, UK.
Grassmann F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.; Health and Medical University, 14471, Potsdam, Germany.
Guénel P; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805, Villejuif, France.
Gündert M; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), C08069120, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, 69120, Heidelberg, Germany.; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Germany.
Haeberle L; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.
Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65, Stockholm, Sweden.; Department of Oncology, 118 83, Sšdersjukhuset, Stockholm, Sweden.
Harkness EF; Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9PT, UK.; Nightingale and Genesis Prevention Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, M23 9LT, UK.; NIHR Manchester Biomedical Research Unit, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.
Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, 70210, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210, Kuopio, Finland.
Hartman M; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 119077, Singapore.; Department of Surgery, National University Health System, Singapore, 119228, Singapore.
Hein A; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Ho WK; Department of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia Campus, 43500, Semenyih, Selangor, Malaysia.; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, 47500, Selangor, Malaysia.
Hooning MJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, 3015 GD, The Netherlands.
Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.; University of Tübingen, 72074, Tübingen, Germany.
Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Houlston RS; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK.
Howell A; Division of Cancer Sciences, University of Manchester, Manchester, M13 9PL, UK.
Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
Huo D; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, 60637, USA.
Ito H; Division of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
Iwasaki M; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center Institute for Cancer Control, Tokyo, 104-0045, Japan.
Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, 71-252, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, 71-252, Szczecin, Poland.
Janni W; Department of Gynaecology and Obstetrics, University Hospital Ulm, 89075, Ulm, Germany.
John EM; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA.
Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SM2 5NG, UK.
Jung A; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Kang D; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea.
Khusnutdinova EK; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, 450054, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, 450000, Russia.
Kim SW; Department of Surgery, Daerim Saint Mary's Hospital, Seoul, 07442, Korea.
Kitahara CM; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Koutros S; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Kristensen VN; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450, Oslo, Norway.; Department of Medical Genetics, Oslo University Hospital and University of Oslo, 0379, Oslo, Norway.
Kubelka-Sabit K; Department of Histopathology and Cytology, Clinical Hospital Acibadem Sistina, Skopje, 1000, Republic of North Macedonia.
Kurian AW; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94304, USA.
Kwong A; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, China.; Department of Surgery, The University of Hong Kong, Hong Kong, China.; Department of Surgery and Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong, China.
Lacey JV; Department of Computational and Quantitative Medicine, City of Hope, Duarte, CA, 91010, USA.; City of Hope Comprehensive Cancer Center, City of Hope, Duarte, CA, 91010, USA.
Lambrechts D; VIB Center for Cancer Biology, 3001, Louvain, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, 3000, Louvain, Belgium.
Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, 96813, USA.
Li J; Human Genetics Division, Genome Institute of Singapore, Singapore, 138672, Singapore.
Linet M; Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.
Lo WY; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.; University of Tübingen, 72074, Tübingen, Germany.
Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK.
Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, 70210, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210, Kuopio, Finland.; Biobank of Eastern Finland, Kuopio University Hospital, Kuopio, Finland.
Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Margolin S; Department of Oncology, 118 83, Sšdersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, 118 83, Stockholm, Sweden.
Matsuo K; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan.
Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, 711 10, Heraklion, Greece.
Menon U; Institute of Clinical Trials and Methodology, University College London, London, WC1V 6LJ, UK.
Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PL, UK.
Murphy RA; School of Population and Public Health, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.; Cancer Control Research, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, 00290, Helsinki, Finland.
Newman WG; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.; North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9WL, UK.
Niederacher D; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, 40225, Düsseldorf, Germany.
O'Brien KM; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Obi N; Institute for Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
Offit K; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Olopade OI; Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, 60637, USA.
Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, 222 42, Lund, Sweden.
Park SK; Cancer Research Institute, Seoul National University, Seoul, 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, 03080, South Korea.
Patel AV; Department of Population Science, American Cancer Society, Atlanta, GA, 30303, USA.
Patel A; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Perou CM; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
Plaseska-Karanfilska D; Research Centre for Genetic Engineering and Biotechnology 'Georgi D. Efremov', MASA, Skopje, 1000, Republic of North Macedonia.
Presneau N; School of Life Sciences, University of Westminster, London, W1W 6UW, UK.
Rack B; Department of Gynaecology and Obstetrics, University Hospital Ulm, 89075, Ulm, Germany.
Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale Dei Tumori (INT), 20133, Milan, Italy.
Ramachandran D; Gynaecology Research Unit, Hannover Medical School, 30625, Hannover, Germany.
Rashid MU; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore, 54000, Pakistan.
Rennert G; Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, 35254, Haifa, Israel.
Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, 28222, Madrid, Spain.
Ruddy KJ; Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA.
Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Saloustros E; Department of Oncology, University Hospital of Larissa, 411 10, Larissa, Greece.
Sandler DP; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Sawyer EJ; School of Cancer and Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, King's College London, London, SE1 9RT, UK.
Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni Van Leeuwenhoek Hospital, Amsterdam, 1066 CX, The Netherlands.
Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.
Schneider MO; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), 91054, Erlangen, Germany.
Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 55905, USA.
Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
Sharma P; Department of Internal Medicine, Division of Medical Oncology, University of Kansas Medical Center, Westwood, KS, 66205, USA.
Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan.; School of Public Health, China Medical University, Taichung, Taiwan.
Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, QC, G1V 4G2, Canada.
Surowy H; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), C08069120, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, 69120, Heidelberg, Germany.
Tamimi RM; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, 10065, USA.
Tapper WJ; Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK.
Taylor JA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.; Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya, 47500, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Teras LR; Department of Population Science, American Cancer Society, Atlanta, GA, 30303, USA.
Toland AE; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, 43210, USA.
Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands.
Torres D; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Institute of Human Genetics, Pontificia Universidad Javeriana, 110231, Bogota, Colombia.
Torres-Mejía G; Center for Population Health Research, National Institute of Public Health, 62100, Cuernavaca, Morelos, Mexico.
Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Truong T; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805, Villejuif, France.
Vachon CM; Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, 55905, USA.
Vijai J; Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Weinberg CR; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Wendt C; Department of Clinical Science and Education, Sšdersjukhuset, Karolinska Institutet, 118 83, Stockholm, Sweden.
Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, 90570, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, 90570, Oulu, Finland.
Wolk A; Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, 751 05, Uppsala, Sweden.
Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Yamaji T; Division of Epidemiology, Center for Public Health Sciences, National Cancer Center Institute for Cancer Control, Tokyo, 104-0045, Japan.
Yang XR; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.
Yu JC; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114, Taiwan.
Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.
Ziogas A; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, 92617, USA.
Ziv E; Department of Medicine, Diller Family Comprehensive Cancer Center, Institute for Human Genetics, UCSF Helen, University of California San Francisco, San Francisco, CA, 94115, USA.
Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK.
Hemingway H; Institute of Health Informatics, University College London, London, UK.; Health Data Research UK, University College London, London, UK.; University College London Hospitals Biomedical Research Centre (UCLH BRC), London, UK.; The Alan Turing Institute, London, UK.
Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Kuchenbaecker KB; Division of Psychiatry, University College London, London, UK. .; UCL Genetics Institute, University College London, London, UK. .
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Corporate Authors:
NBCS Collaborators
CTS Consortium
ABCTB Investigators
Źródło:
Genome medicine [Genome Med] 2023 Jan 26; Vol. 15 (1), pp. 7. Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Breast Neoplasms*/genetics
Humans ; Female ; Genetic Predisposition to Disease ; Black People ; Genetic Testing ; Genome-Wide Association Study/methods ; Polymorphism, Single Nucleotide ; Formins/genetics
Czasopismo naukowe
Tytuł:
Improved Bladder Tumor RNA Isolation from Archived Tissues Using Methylene Blue for Normalization, Multiplex RNA Hybridization, Sequencing and Subtyping.
Autorzy:
Köhler SA; Laboratory for Molecular Medicine, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitaetsstrasse 21-23, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.
Brandl L; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Strissel PL; Laboratory for Molecular Medicine, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitaetsstrasse 21-23, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Gloßner L; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Angeloni M; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Ferrazzi F; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.; Department of Nephropathology, Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Bahlinger V; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Hartmann A; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Beckmann MW; Laboratory for Molecular Medicine, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitaetsstrasse 21-23, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.
Eckstein M; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.; Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Krankenhausstrasse 8-10, 91054 Erlangen, Germany.
Strick R; Laboratory for Molecular Medicine, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Universitaetsstrasse 21-23, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), University Hospital Erlangen, Östliche Stadtmauerstrasse 30, 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 06; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
RNA*/analysis
RNA*/genetics
Urinary Bladder Neoplasms*/drug therapy
Urinary Bladder Neoplasms*/genetics
Formaldehyde/chemistry ; Gene Expression Profiling/methods ; Humans ; Methylene Blue/pharmacology ; Nucleotides ; Paraffin Embedding/methods ; RNA, Messenger/genetics ; Tissue Fixation/methods
Czasopismo naukowe
Tytuł:
Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study.
Autorzy:
Jablonski J; Department of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Hoffmann L; Department of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Blümcke I; Department of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Fejtová A; Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Uebe S; NGS Core Unit, Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Ekici AB; NGS Core Unit, Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Gnatkovsky V; Department of Epileptology, University Hospital Bonn, 53127 Bonn, Germany.
Kobow K; Department of Neuropathology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
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Źródło:
Cells [Cells] 2021 Nov 03; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Brain/*pathology
Epilepsy/*pathology
Neurons/*pathology
Animals ; Calbindins/metabolism ; Calcium/metabolism ; Cells, Cultured ; DNA Methylation/genetics ; Epigenesis, Genetic ; Epilepsy/genetics ; GABAergic Neurons/pathology ; Gene Regulatory Networks ; Neurons/metabolism ; Principal Component Analysis ; Rats ; Time Factors
Czasopismo naukowe
Tytuł:
Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.
Autorzy:
Escala-Garcia M; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Canisius S; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Beesley J; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Anton-Culver H; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Augustinsson A; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Becher H; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
Behrens S; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bermisheva M; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.
Bojesen SE; Copenhagen University Hospital, Copenhagen General Population Study, Herlev, Denmark.; Gentofte Hospital, Herlev, Denmark.; Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bolla MK; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Castelao JE; Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Oncology and Genetics Unit, Vigo, Spain.
Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Medical Center Hamburg-Eppendorf, Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), Hamburg, Germany.
Chanock SJ; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA.
Dennis J; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Devilee P; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Dörk T; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Easton DF; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Ekici AB; Institute of Human Genetics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
Eliassen AH; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.; Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Flyger H; Department of Breast Surgery, Copenhagen University Hospital, Herlev, Denmark.
Gago-Dominguez M; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
García-Closas M; Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
García-Sáenz JA; Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC), Medical Oncology Department, Hospital Clínico San Carlos, Madrid, Spain.
Geisler J; Department of Oncology, Akershus University Hospital, Lørenskog, Norway.
Giles GG; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, VIC, Australia.; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.
Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland.
Gündert M; German Cancer Research Center (DKFZ), Molecular Epidemiology Group, C080, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.; Helmholtz Zentrum München, Institute of Diabetes Research, German Research Center for Environmental Health, Neuherberg, Germany.
Hahnen E; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Håkansson N; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden.
Hamann U; German Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, Heidelberg, Germany.
Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.
Heemskerk-Gerritsen BAM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.
Hopper JL; Melbourne School of Population and Global Health, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, VIC, Australia.
Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Jacot W; Institut du Cancer de Montpellier, Montpellier University, Montpellier, France.
Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.; Independent Laboratory of Molecular Biology and Genetic Diagnostics, Pomeranian Medical University, Szczecin, Poland.
John EM; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.; Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.
Jung AY; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia.; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russia.
Koppert LB; Department of Surgical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Harvard T.H. Chan School of Public Health, Program in Genetic Epidemiology and Statistical Genetics, Boston, MA, USA.
Kristensen VN; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Kurian AW; Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.; Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.
Lambrechts D; VIB Center for Cancer Biology, Leuven, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium.
Le Marchand L; University of Hawaii Cancer Center, Epidemiology Program, Honolulu, HI, USA.
Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Luben RN; NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, England, UK.; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Cambridge, UK.
Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Biobank of Eastern Finland, Kuopio, Finland.
Manoochehri M; German Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, Heidelberg, Germany.
Margolin S; Department of Oncology, Sšdersjukhuset, Stockholm, Sweden.; Department of Clinical Science and Education, Karolinska Institutet, Sšdersjukhuset, Stockholm, Sweden.
Mavroudis D; Department of Medical Oncology, University Hospital of Heraklion, Heraklion, Greece.
Muranen TA; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Olshan AF; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Olsson H; Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden.
Park-Simon TW; Gynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Patel AV; Department of Population Science, American Cancer Society, Atlanta, GA, USA.
Peterlongo P; IFOM-The FIRC Institute of Molecular Oncology, Genome Diagnostics Program, Milan, Italy.
Pharoah PDP; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Punie K; Department of General Medical Oncology and Multidisciplinary Breast Centre, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
Rennert G; Carmel Medical Center and Technion Faculty of Medicine, Clalit National Cancer Control Center, Haifa, Israel.
Rennert HS; Carmel Medical Center and Technion Faculty of Medicine, Clalit National Cancer Control Center, Haifa, Israel.
Romero A; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Roylance R; Department of Oncology, UCLH Foundation Trust, London, UK.
Rüdiger T; Institute of Pathology, Staedtisches Klinikum Karlsruhe, Karlsruhe, Germany.
Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Erlangen, Germany.
Saloustros E; Department of Oncology, University Hospital of Larissa, Larissa, Greece.
Sawyer EJ; School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, King's College London, Guy's Campus, London, UK.
Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology (CIO), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
Scott C; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Southey MC; Cancer Council Victoria, Cancer Epidemiology Division, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.
Surowy H; German Cancer Research Center (DKFZ), Molecular Epidemiology Group, C080, Heidelberg, Germany.; Molecular Biology of Breast Cancer, University Womens Clinic Heidelberg, University of Heidelberg, Heidelberg, Germany.
Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Tamimi RM; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Teras LR; Department of Population Science, American Cancer Society, Atlanta, GA, USA.
Thomas E; Plateforme de Bioinformatique Gilles Thomas, Centre de recherche en cancérologie de Lyon, Fondation Synergie Lyon Cancer, Université Claude Bernard Lyon 1, Lyon, France.
Tomlinson I; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Wellcome Trust Centre for Human Genetics and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
Troester MA; Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Vachon CM; Division of Epidemiology, Department of Health Science Research, Mayo Clinic, Rochester, MN, USA.
Wang Q; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.
Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, University of Oulu, Biocenter Oulu, Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu, Finland.
Wolk A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Ziogas A; Department of Medicine, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA.
Michailidou K; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.; Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus.
Chenevix-Trench G; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Bachelot T; Département de Cancérologie Médicale, Centre Léon Bérard, Lyon, France.
Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands. .; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. .
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Corporate Authors:
kConFab/AOCS Investigators
Źródło:
Scientific reports [Sci Rep] 2021 Oct 05; Vol. 11 (1), pp. 19787. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cancer Survivors*
Genetic Variation*
Breast Neoplasms/*genetics
Breast Neoplasms/*mortality
Germ Cells/*metabolism
Biomarkers, Tumor ; Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Female ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Humans ; Kaplan-Meier Estimate ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
Autorzy:
Park J; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.; BK21plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Korea.
Choi JY; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.; BK21plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Korea.; Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul 03080, Korea.; Cancer Research Institute, Seoul National University, Seoul 03080, Korea.
Choi J; Institute of Health Policy and Management, Seoul National University Medical Research Center, Seoul 03080, Korea.
Chung S; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.
Song N; College of Pharmacy, Chungbuk National University, Cheongju-si 28160, Korea.
Park SK; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.; Cancer Research Institute, Seoul National University, Seoul 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
Han W; Cancer Research Institute, Seoul National University, Seoul 03080, Korea.; Department of Surgery, Seoul National University College of Medicine, Seoul 03080, Korea.
Noh DY; Cancer Research Institute, Seoul National University, Seoul 03080, Korea.; Department of Surgery, Seoul National University College of Medicine, Seoul 03080, Korea.
Ahn SH; Department of Surgery, Medicine and ASAN Medical Center, University of Ulsan College, Seoul 05505, Korea.
Lee JW; Department of Surgery, Medicine and ASAN Medical Center, University of Ulsan College, Seoul 05505, Korea.
Kim MK; Division of Cancer Epidemiology and Management, National Cancer Center, Goyang-si 10408, Korea.
Jee SH; Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul 03722, Korea.
Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.
Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.
Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.
Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.; Biostatistics Unit, The Cyprus Institute of Neurology & Genetics, Nicosia 2371, Cyprus.; Cyprus School of Molecular Medicine, The Cyprus Institute of Neurology & Genetics, Nicosia 23462, Cyprus.
Shah M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Conroy DM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Harrington PA; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Mayes R; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65 Stockholm, Sweden.
Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 65 Stockholm, Sweden.; Department of Oncology, Södersjukhuset, 118 83 Stockholm, Sweden.
Teras LR; Department of Population Science, American Cancer Society, Atlanta, GA 30303, USA.
Patel AV; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Sawyer EJ; School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, King's College London, London SE1 9RT, UK.
Roylance R; Department of Oncology, UCLH Foundation Trust, London NW1 2PG, UK.
Bojesen SE; Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Flyger H; Department of Breast Surgery, Herlev and Gentofte Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.
Lambrechts D; VIB Center for Cancer Biology, 3001 Leuve, Belgium.; Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
Baten A; Department of Radiotherapy Oncology, KU Leuven-University of Leuven, University Hospitals Leuven, 3000 Leuven, Belgium.
Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464-8681, Japan.; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Ito H; Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Guénel P; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805 Villejuif, France.
Truong T; Center for Research in Epidemiology and Population Health (CESP), Team Exposome and Heredity, INSERM, University Paris-Saclay, 94805 Villejuif, France.
Keeman R; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.
Schmidt MK; Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.; Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands.
Wu AH; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Tseng CC; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Cox A; Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2TN, UK.
Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2TN, UK.
kConFab Investigators; Peter MacCallum Cancer Center, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
Andrulis IL; Fred A, Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC 3010, Australia.
Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC 3010, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC 3004, Australia.
Wu PE; Taiwan Biobank, Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.
Shen CY; Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.; School of Public Health, China Medical University, Taichung 404, Taiwan.
Fasching PA; Department of Medicine Division of Hematology and Oncology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, 91054 Erlangen, Germany.
Ekici AB; Institute of Human Genetics, Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.
Muir K; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Lophatananon A; Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London SM2 5NG, UK.
Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London SM2 5NG, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London SW7 3RP, UK.
Hoppe R; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tübingen, 72074 Tübingen, Germany.
Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53177 Bonn, Germany.
Hartman M; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore.; Department of Surgery, National University Health System, Singapore 119228, Singapore.
Li J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore.
Mannermaa A; Translational Cancer Research Area, University of Eastern Finland, 70210 Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Biobank of Eastern Finland, Kuopio University Hospital, 70210 Kuopio, Finland.
Hartikainen JM; Translational Cancer Research Area, University of Eastern Finland, 70210 Kuopio, Finland.; Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, 70210 Kuopio, Finland.
Benitez J; Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain.; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
González-Neira A; Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Dörk T; Gynaecology Research Unit, Hannover Medical School, 30625 Hannover, Germany.
Bogdanova NV; Gynaecology Research Unit, Hannover Medical School, 30625 Hannover, Germany.; Department of Radiation Oncology, Hannover Medical School, 30625 Hannover, Germany.; NN Alexandrov Research Institute of Oncology and Medical Radiology, 223040 Minsk, Belarus.
Teo SH; Breast Cancer Research Programme, Cancer Research Malaysia, Subang Jaya 47500, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Mohd Taib NA; Breast Cancer Research Unit, University Malaya Cancer Research Institute, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Fletcher O; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW7 3RP, UK.
Johnson N; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW7 3RP, UK.
Grip M; Department of Surgery, Oulu University Hospital, University of Oulu, 90220 Oulu, Finland.
Winqvist R; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, 90570 Oulu, Finland.; Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre Oulu, Oulu 90570, Finland.
Blomqvist C; Department of Oncology, Helsinki University Hospital, University of Helsinki, 00290 Helsinki, Finland.; Department of Oncology, Örebro University Hospital, 70185 Örebro, Sweden.
Nevanlinna H; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, 00290 Helsinki, Finland.
Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76 Stockholm, Sweden.; Department of Clinical Genetics, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Wendt C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 118 83 Stockholm, Sweden.
Kristensen VN; Department of Medical Genetics, Oslo University Hospital and University of Oslo, 0450 Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.
Nbcs Collaborators; Department of Medical Genetics, Oslo University Hospital and University of Oslo, 0450 Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.; Department of Research, Vestre Viken Hospital, 3004 Drammen, Norway.; Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, 0450 Oslo, Norway.; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, 0450 Oslo, Norway.; Section for Breast- and Endocrine Surgery, Department of Cancer, Division of Surgery, Cancer and Transplantation Medicine, Oslo University Hospital-Ullevål, 0450 Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, 0450 Oslo, Norway.; Department of Pathology at Akershus University Hospital, 1478 Lørenskog, Norway.; Department of Oncology, Division of Surgery and Cancer and Transplantation Medicine, University Hospital-Radiumhospitalet, 0405 Oslo, Norway.; National Advisory Unit on Late Effects after Cancer Treatment, Department of Oncology, Oslo University Hospital, 0405 Oslo, Norway.; Department of Oncology, Akershus University Hospital, 1478 Lørenskog, Norway.; Oslo Breast Cancer Research Consortium, Oslo University Hospital, 0405 Oslo, Norway.
Tollenaar RAEM; Department of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Heemskerk-Gerritsen BAM; Department of Medical Oncology, Erasmus MC Cancer Institute, 3015 CN Rotterdam, The Netherlands.
Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Bonanni B; Division of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Lacey JV; Department of Computational and Quantitative Medicine, City of Hope, Duarte, CA 91010, USA.; City of Hope Comprehensive Cancer Center, City of Hope, Duarte, CA 91010, USA.
Martinez ME; Moores Cancer Center, University of California San Diego, La Jolla, CA 92037, USA.; Herbert Wertheim School of Public Health and Longevity Science, University of California San Diego, La Jolla, CA 92161, USA.
Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Pharoah PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 0SR, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Yoo KY; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
Kang D; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.; Cancer Research Institute, Seoul National University, Seoul 03080, Korea.; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2021 May 14; Vol. 13 (10). Date of Electronic Publication: 2021 May 14.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Loss of PHF6 leads to aberrant development of human neuron-like cells.
Autorzy:
Fliedner A; Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Gregor A; Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Ferrazzi F; Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Ekici AB; Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Sticht H; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany.
Zweier C; Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91054, Erlangen, Germany. .; Department of Human Genetics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, 3010, Bern, Switzerland. .
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 19030. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Knockdown Techniques*
Neurons/*cytology
Repressor Proteins/*genetics
CRISPR-Cas Systems ; Epilepsy/genetics ; Epilepsy/pathology ; Face/abnormalities ; Face/pathology ; Female ; Growth Disorders/genetics ; Growth Disorders/pathology ; Humans ; Hypogonadism/genetics ; Hypogonadism/pathology ; Intellectual Disability/genetics ; Male ; Mental Retardation, X-Linked/genetics ; Mental Retardation, X-Linked/pathology ; Mutation, Missense ; Neurons/metabolism ; Obesity/genetics ; Obesity/pathology
SCR Disease Name:
Borjeson-Forssman-Lehmann syndrome
Czasopismo naukowe
Tytuł:
HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment.
Autorzy:
Wuerfel FM; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Huebner H; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Häberle L; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Gass P; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Hein A; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Jud SM; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Hack CC; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Wunderle M; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Schulz-Wendtland R; Institute of Diagnostic Radiology, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Erlangen, Germany.
Erber R; Institute of Pathology, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Erlangen, Germany.
Hartmann A; Institute of Pathology, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Erlangen, Germany.
Ekici AB; Institute of Human Genetics, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Erlangen, Germany.
Beckmann MW; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Fasching PA; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany.
Ruebner M; Department of Gynaecology and Obstetrics, Erlangen University Hospital, Comprehensive Cancer Center Erlangen-EMN, Friedrich Alexander University of Erlangen-Nuremberg (FAU), Universitätsstrasse 21-23, 91054, Erlangen, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2020 Sep 25; Vol. 10 (1), pp. 15750. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*drug therapy
HLA-G Antigens/*metabolism
Histocompatibility Antigens Class I/*metabolism
Neoadjuvant Therapy/*methods
Adult ; Aged ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Middle Aged ; Prognosis ; Prospective Studies ; Protein Isoforms/metabolism ; Receptor, ErbB-2/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Genetic interaction screen for severe neurodevelopmental disorders reveals a functional link between Ube3a and Mef2 in Drosophila melanogaster.
Autorzy:
Straub J; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Gregor A; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Sauerer T; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Fliedner A; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Distel L; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Suchy C; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Ekici AB; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Ferrazzi F; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany.
Zweier C; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054, Erlangen, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jan 27; Vol. 10 (1), pp. 1204. Date of Electronic Publication: 2020 Jan 27.
Typ publikacji:
Journal Article
MeSH Terms:
Drosophila Proteins/*genetics
Drosophila melanogaster/*genetics
Epistasis, Genetic/*genetics
Myogenic Regulatory Factors/*genetics
Neurodevelopmental Disorders/*genetics
Ubiquitin-Protein Ligases/*genetics
Animals ; Disease Models, Animal ; Eye/metabolism ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; MEF2 Transcription Factors/genetics ; Neuroglia/metabolism ; Phenotype ; RNA, Small Interfering ; Transfection ; Wings, Animal/metabolism
Czasopismo naukowe

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