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    Wyświetlanie 1-3 z 3
    Tytuł:
    Elucidation of Natural Components of Gardenia thunbergia Thunb. Leaves: Effect of Methanol Extract and Rutin on Non-Alcoholic Fatty Liver Disease.
    Autorzy:
    El-Shial EM; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Horus University, New Damietta 34518, Egypt.
    Kabbash A; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
    El-Aasr M; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
    El-Feky OA; Department of Biochemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
    El-Sherbeni SA; Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2023 Jan 16; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 16.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gardenia*/chemistry
    Non-alcoholic Fatty Liver Disease*/drug therapy
    Non-alcoholic Fatty Liver Disease*/etiology
    Plant Extracts*/pharmacology
    Animals ; Mice ; Diet, High-Fat/adverse effects ; Liver ; Methanol ; Mice, Inbred C57BL ; Rutin/pharmacology ; Tandem Mass Spectrometry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors.
    Autorzy:
    Abdallah AE; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
    Mabrouk RR; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
    Al Ward MMS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
    Eissa SI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
    Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
    Mehany ABM; Zoology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
    Abo-Saif MA; Biochemistry Department, Faculty of Pharmacy, Tanta university, Tanta, Egypt.
    El-Feky OA; Biochemistry Department, Faculty of Pharmacy, Tanta university, Tanta, Egypt.
    Alesawy MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
    El-Zahabi MA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
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    Źródło:
    Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 573-591.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Molecular Docking Simulation*
    Antineoplastic Agents/*pharmacology
    Apoptosis/*drug effects
    Protein Kinase Inhibitors/*pharmacology
    Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors
    Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Nitrobenzenes/chemical synthesis ; Nitrobenzenes/chemistry ; Nitrobenzenes/pharmacology ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Quinazolines/chemical synthesis ; Quinazolines/chemistry ; Quinazolines/pharmacology ; Quinoxalines/chemical synthesis ; Quinoxalines/chemistry ; Quinoxalines/pharmacology ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Biological Effect of Quercetin in Repairing Brain Damage and Cerebral Changes in Rats: Molecular Docking and In Vivo Studies.
    Autorzy:
    Mehany ABM; Department of Zoology, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
    Belal A; Medicinal Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P. O. Box 11099, Taif 21944, Saudi Arabia.
    Santali EY; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P. O. Box 11099, Taif 21944, Saudi Arabia.
    Shaaban S; Department of Microbiology & Immunology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
    Abourehab MAS; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.; Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Minia University, Minia 61519, Egypt.
    El-Feky OA; Biochemistry Department, Faculty of Pharmacy, Tanta University, Tanta 3111, Egypt.
    Diab M; Anatomy and Embryology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
    Abou Galala FMA; Department of Anatomy, Faculty of Medicine, Damita, Al-Azhar University, Cairo, Egypt.
    Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia.
    Abdelhamid G; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Egypt.
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    Źródło:
    BioMed research international [Biomed Res Int] 2022 Apr 26; Vol. 2022, pp. 8962149. Date of Electronic Publication: 2022 Apr 26 (Print Publication: 2022).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain Injuries*/drug therapy
    Quercetin*/pharmacology
    Animals ; Antioxidants/pharmacology ; Brain/metabolism ; Catalase/metabolism ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Glutathione Transferase/metabolism ; Molecular Docking Simulation ; Oxidative Stress ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-3 z 3

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