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    Wyświetlanie 1-3 z 3
    Tytuł:
    A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer.
    Autorzy:
    Cario CL; Program in Biological and Medical Informatics, University of California, San Francisco, California, 94158, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, 94158, USA.
    Chen E; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, 94158, USA.
    Leong L; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, 94158, USA.
    Emami NC; Program in Biological and Medical Informatics, University of California, San Francisco, California, 94158, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, 94158, USA.
    Lopez K; Department of Urology, University of California, San Francisco, California, 94158, USA.
    Tenggara I; Department of Urology, University of California, San Francisco, California, 94158, USA.
    Simko JP; Department of Urology, University of California, San Francisco, California, 94158, USA.; Department of Anatomic Pathology, University of California, San Francisco, California, 94158, USA.
    Friedlander TW; Division of Hematology/Oncology, University of California, San Francisco, California, 94158, USA.
    Li PS; Division of Hematology/Oncology, University of California, San Francisco, California, 94158, USA.
    Paris PL; Department of Urology, University of California, San Francisco, California, 94158, USA.; Division of Hematology/Oncology, University of California, San Francisco, California, 94158, USA.
    Carroll PR; Department of Urology, University of California, San Francisco, California, 94158, USA.
    Witte JS; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, 94158, USA. .; Department of Urology, University of California, San Francisco, California, 94158, USA. .
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    Źródło:
    BMC cancer [BMC Cancer] 2020 Aug 28; Vol. 20 (1), pp. 820. Date of Electronic Publication: 2020 Aug 28.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Genome, Human*
    Machine Learning*
    Base Sequence/*genetics
    Circulating Tumor DNA/*genetics
    Prostatic Neoplasms/*genetics
    Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/isolation & purification ; Circulating Tumor DNA/isolation & purification ; Cohort Studies ; Humans ; Male ; Middle Aged ; Mutation ; Sequence Analysis, DNA/methods ; Whole Genome Sequencing/methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
    Autorzy:
    Ferreira MAR; Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
    Vonk JM; University of Groningen, University Medical Center Groningen, Epidemiology, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
    Baurecht H; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
    Marenholz I; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.
    Tian C; 23andMe, Inc., Mountain View, California, United States of America.
    Hoffman JD; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America.
    Helmer Q; Department Biological Psychology, Netherlands Twin Register, Vrije University, Amsterdam, The Netherlands.
    Tillander A; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
    Ullemar V; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
    Lu Y; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
    Grosche S; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
    Rüschendorf F; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.
    Granell R; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.
    Brumpton BM; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Thoracic Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
    Fritsche LG; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
    Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
    Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
    Nielsen JB; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
    Zhou W; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
    Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
    Langhammer A; The HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
    Holmen OL; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.
    Løset M; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Dermatology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
    Abecasis GR; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
    Willer CJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
    Emami NC; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America.
    Cavazos TB; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.
    Witte JS; Program in Biological and Medical Informatics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America.; Institute for Human Genetics, University of California, San Francisco, San Francisco, California, United States of America.; Department of Urology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, United States of America.
    Szwajda A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Hinds DA; 23andMe, Inc., Mountain View, California, United States of America.
    Hübner N; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.
    Weidinger S; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
    Magnusson PK; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
    Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, California, United States of America.
    Karlsson R; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.
    Paternoster L; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, United Kingdom.
    Boomsma DI; Department Biological Psychology, Netherlands Twin Register, Vrije University, Amsterdam, The Netherlands.
    Almqvist C; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden.; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
    Lee YA; Max Delbrück Center (MDC) for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center of Charité Universitätsmedizin Berlin and Max Delbrück Center, Berlin, Germany.
    Koppelman GH; University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Pediatric Pulmonology and Pediatric Allergology, and University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
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    Corporate Authors:
    23andMe Research Team
    collaborators of the SHARE study
    Źródło:
    PLoS genetics [PLoS Genet] 2020 Jun 30; Vol. 16 (6), pp. e1008725. Date of Electronic Publication: 2020 Jun 30 (Print Publication: 2020).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Polymorphism, Single Nucleotide*
    Asthma/*genetics
    Eczema/*genetics
    Rhinitis, Allergic, Seasonal/*genetics
    Adolescent ; Adult ; Age of Onset ; Aged ; Asthma/pathology ; Child ; Eczema/pathology ; Female ; Genetic Loci ; Genome-Wide Association Study/methods ; Humans ; Male ; Middle Aged ; Rhinitis, Allergic, Seasonal/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk.
    Autorzy:
    Hoffman JD; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Graff RE; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Emami NC; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.; Program in Biological and Medical Informatics, University of California San Francisco, San Francisco, CA, United States of America.
    Tai CG; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Passarelli MN; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, United States of America.
    Hu D; Department of Medicine, University of California San Francisco, San Francisco, CA, United States of America.
    Huntsman S; Department of Medicine, University of California San Francisco, San Francisco, CA, United States of America.
    Hadley D; Department of Pediatrics, University of California San Francisco, San Francisco, CA, United States of America.
    Leong L; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Majumdar A; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Zaitlen N; Department of Medicine, University of California San Francisco, San Francisco, CA, United States of America.
    Ziv E; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.
    Witte JS; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.; Department of Urology, University of California San Francisco, San Francisco, CA, United States of America.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, United States of America.
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    Źródło:
    PLoS genetics [PLoS Genet] 2017 Mar 31; Vol. 13 (3), pp. e1006690. Date of Electronic Publication: 2017 Mar 31 (Print Publication: 2017).
    Typ publikacji:
    Journal Article; Meta-Analysis
    MeSH Terms:
    Genetic Predisposition to Disease*
    Breast Neoplasms/*genetics
    Carrier Proteins/*genetics
    GTPase-Activating Proteins/*genetics
    Membrane Proteins/*genetics
    Quantitative Trait Loci/*genetics
    Breast/metabolism ; Breast/pathology ; Breast Neoplasms/blood ; Breast Neoplasms/pathology ; Carrier Proteins/blood ; Endonucleases/blood ; Endonucleases/genetics ; Ethnicity ; Female ; GTPase-Activating Proteins/blood ; Genome-Wide Association Study ; Humans ; Membrane Proteins/blood ; Polymorphism, Single Nucleotide ; Risk Factors ; Transcriptome/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-3 z 3

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