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Wyszukujesz frazę ""Embryo, Mammalian"" wg kryterium: Temat


Tytuł:
Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells.
Autorzy:
Grzonka M; Department of Cell Biology of the Skin and Department of Dermatology and Venereology, Medical Faculty, University of Cologne, Cologne, Germany.; The Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD), Medical Faculty, University of Cologne, Cologne, Germany.; Graduate School for Biological Sciences, University of Cologne, Cologne, Germany.
Bazzi H; Department of Cell Biology of the Skin and Department of Dermatology and Venereology, Medical Faculty, University of Cologne, Cologne, Germany.; The Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases (CECAD), Medical Faculty, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne, Cologne, Germany.
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Źródło:
ELife [Elife] 2024 Feb 26; Vol. 13. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/metabolism
Centrioles*/metabolism
Protein Serine-Threonine Kinases*/metabolism
Embryo, Mammalian*/cytology
Embryo, Mammalian*/metabolism
Animals ; Humans ; Mice ; Centrosome/metabolism ; Embryonic Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
A single-cell time-lapse of mouse prenatal development from gastrula to birth.
Autorzy:
Qiu C; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .
Martin BK; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Welsh IC; The Jackson Laboratory, Bar Harbor, ME, USA.
Daza RM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Le TM; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Huang X; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.
Nichols EK; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Taylor ML; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Fulton O; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
O'Day DR; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Gomes AR; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Ilcisin S; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Srivatsan S; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Medical Scientist Training Program, University of Washington, Seattle, WA, USA.
Deng X; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Disteche CM; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.
Noble WS; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.
Hamazaki N; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.
Moens CB; Division of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Kimelman D; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Cao J; Laboratory of Single-Cell Genomics and Population dynamics, The Rockefeller University, New York, NY, USA.
Schier AF; Biozentrum, University of Basel, Basel, Switzerland.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
Spielmann M; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Human Genetics, University Hospitals Schleswig-Holstein, University of Lübeck and Kiel University, Lübeck, Kiel, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg, Lübeck, Kiel, Lübeck, Germany.
Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA.
Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.; Seattle Hub for Synthetic Biology, Seattle, WA, USA.
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA. .; Seattle Hub for Synthetic Biology, Seattle, WA, USA. .
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Źródło:
Nature [Nature] 2024 Feb; Vol. 626 (8001), pp. 1084-1093. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Animals, Newborn*/embryology
Animals, Newborn*/genetics
Embryo, Mammalian*/cytology
Embryo, Mammalian*/embryology
Embryonic Development*/genetics
Gastrula*/cytology
Gastrula*/embryology
Single-Cell Analysis*
Time-Lapse Imaging*
Animals ; Female ; Mice ; Pregnancy ; Cell Differentiation/genetics ; Gastrulation/genetics ; Kidney/cytology ; Kidney/embryology ; Mesoderm/cytology ; Mesoderm/enzymology ; Neurons/cytology ; Neurons/metabolism ; Retina/cytology ; Retina/embryology ; Somites/cytology ; Somites/embryology ; Time Factors ; Transcription Factors/genetics ; Transcription, Genetic ; Organ Specificity/genetics
Czasopismo naukowe
Tytuł:
Single-cell RNA-seq and single-cell bisulfite-sequencing reveal insights into yak preimplantation embryogenesis.
Autorzy:
Yu T; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zhang C; Academician Zhang Yong Innovation Center, Xining Animal Disease Control Center, Xining, Qinghai, China.
Song W; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Zhao X; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Cheng Y; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
Liu J; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. Electronic address: .
Su J; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105562. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Blastocyst*/metabolism
DNA Methylation*
Embryonic Development*/genetics
Gene Expression Regulation, Developmental*
Single-Cell Gene Expression Analysis*
Sulfites*/metabolism
Embryo, Mammalian*/embryology
Embryo, Mammalian*/enzymology
Animals ; Cattle ; Female ; Pregnancy ; Epigenesis, Genetic ; Gene Expression Profiling ; Histone Deacetylase 1/metabolism ; Histone Deacetylase 2/metabolism ; Ubiquitin-Specific Peptidase 7/metabolism
Czasopismo naukowe
Tytuł:
Emergence of replication timing during early mammalian development.
Autorzy:
Nakatani T; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany.
Schauer T; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany.
Altamirano-Pacheco L; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany.
Klein KN; Department of Biological Science, Florida State University, Tallahassee, FL, USA.
Ettinger A; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany.
Pal M; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany.
Gilbert DM; Laboratory of Chromosome Replication and Epigenome Regulation, San Diego Biomedical Research Institute, San Diego, CA, USA.
Torres-Padilla ME; Institute of Epigenetics and Stem Cells, Helmholtz Munich, Munich, Germany. .; Faculty of Biology, Ludwig-Maximilians Universität, Munich, Germany. .
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Źródło:
Nature [Nature] 2024 Jan; Vol. 625 (7994), pp. 401-409. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Replication Timing*
Genome*/genetics
Embryo, Mammalian*/cytology
Embryo, Mammalian*/embryology
Embryo, Mammalian*/metabolism
Animals ; Mice ; Blastocyst/cytology ; Blastocyst/metabolism ; Chromatin/genetics ; Epigenome/genetics ; RNA Polymerase II/metabolism ; Zygote/cytology ; Zygote/growth & development ; Zygote/metabolism
Czasopismo naukowe
Tytuł:
EVATOM: an optical, label-free, machine learning assisted embryo health assessment tool.
Autorzy:
Goswami N; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Beckman Institute of Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .
Winston N; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Choi W; Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Lai NZE; Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Arcanjo RB; Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.; Department of Animal Science, University of California, Davis, CA, 95616, USA.
Chen X; Beckman Institute of Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.; School of Applied and Engineering Physics, Cornell University, Ithaca, NY, 14850, USA.
Sobh N; NCSA Center for Artificial Intelligence Innovation, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Nowak RA; Department of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .
Anastasio MA; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Beckman Institute of Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .; Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. .
Popescu G; Department of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.; Beckman Institute of Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.; Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
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Źródło:
Communications biology [Commun Biol] 2024 Mar 05; Vol. 7 (1), pp. 268. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*
Fertilization in Vitro*
Female ; Pregnancy ; Humans ; Health Status ; Machine Learning ; Microscopy, Confocal
Czasopismo naukowe
Tytuł:
Effect of additional cytoplasm injection on the cloned bovine embryo organelle distribution and stress mitigation.
Autorzy:
Kang JS; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea. Electronic address: .
Joo MD; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea. Electronic address: .
Lee SH; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Kang SM; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Haider Z; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Perera CD; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Idrees M; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea; Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea.
Jin Y; Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, 130062, Jilin, PR China. Electronic address: .
Kong IK; Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, 130062, Jilin, PR China; Division of Applied Life Science (BK21 Four), Graduate School of Applied Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea; Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea; Thekingkong Co. Ltd., Gyeongsang National University, Jinju, 52828, Republic of Korea. Electronic address: .
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Źródło:
Theriogenology [Theriogenology] 2024 Mar 01; Vol. 216, pp. 12-19. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*
Cloning, Organism*/veterinary
Animals ; Cattle ; Nuclear Transfer Techniques/veterinary ; Blastocyst ; Embryonic Development ; Fertilization in Vitro/veterinary ; Endoplasmic Reticulum
Czasopismo naukowe
Tytuł:
Mule embryos share identical morphological features to horse embryos.
Autorzy:
Podico G; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Canisso IF; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA. Electronic address: .
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Źródło:
Theriogenology [Theriogenology] 2024 Mar 01; Vol. 216, pp. 196-202. Date of Electronic Publication: 2023 Dec 01.
Typ publikacji:
Randomized Controlled Trial, Veterinary; Journal Article
MeSH Terms:
Equidae*
Embryo, Mammalian*
Horses ; Animals ; Female ; Male ; Ovulation ; Semen ; Cross-Over Studies
Czasopismo naukowe
Tytuł:
An extended wave of global mRNA deadenylation sets up a switch in translation regulation across the mammalian oocyte-to-embryo transition.
Autorzy:
Lee K; Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Cho K; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Morey R; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Cook-Andersen H; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2024 Feb 27; Vol. 43 (2), pp. 113710. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*
Gene Expression Profiling*
Animals ; Mice ; Oocytes ; RNA, Messenger/genetics ; Mammals
Czasopismo naukowe
Tytuł:
Extra (embryonic) dialogues: Keys to improved stem cell-based embryo models.
Autorzy:
Chandrasekaran AP; Stem Cell and Regeneration Laboratory, Bioscience Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Li M; Stem Cell and Regeneration Laboratory, Bioscience Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia; Bioengineering Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia. Electronic address: .
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Źródło:
Cell stem cell [Cell Stem Cell] 2024 Feb 01; Vol. 31 (2), pp. 155-157.
Typ publikacji:
Journal Article
MeSH Terms:
Stem Cells*
Embryo, Mammalian*
Humans ; Cell Culture Techniques ; Regenerative Medicine ; Embryonic Development ; Cell Differentiation
Czasopismo naukowe
Tytuł:
Re-defining the human embryo : A legal perspective on the creation of embryos in research.
Autorzy:
De Miguel Beriain I; UPV/EHU, Leioa, Spain.; Basque Foundation of Science, Bilbao, Spain.
Rueda J; University of California-San Diego, Institute for Practical Ethics, San Diego, California, 92109, USA. .; University of Granada, Granada, Spain. .
Villalba A; University of Granada, Granada, Spain.; Université Paris Cité, Paris, France.
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Źródło:
EMBO reports [EMBO Rep] 2024 Feb; Vol. 25 (2), pp. 467-470. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*
Embryo Research*
Humans ; Fertilization in Vitro
Czasopismo naukowe
Tytuł:
Topical section: embryonic models (2023) for Current Opinion in Genetics & Development.
Autorzy:
Handford CE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. Electronic address: https:.
Junyent S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. Electronic address: https:.
Jorgensen V; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Zernicka-Goetz M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. Electronic address: .
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Źródło:
Current opinion in genetics & development [Curr Opin Genet Dev] 2024 Feb; Vol. 84, pp. 102134. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Embryonic Development*/genetics
Embryo, Mammalian*
Animals ; Female ; Pregnancy ; Organogenesis ; Stem Cells ; Mammals
Czasopismo naukowe
Tytuł:
Pudgy mouse rib deformities emanate from abnormal paravertebral longitudinal cartilage/bone accumulations.
Autorzy:
Shapiro F; Department of Medicine/Endocrinology, Stanford University School of Medicine, Palo Alto CA 94305, USA.; Department of Bioengineering, Northeastern University, Boston MA 02115, USA.
Wang J; Department of Medicine/Endocrinology, Stanford University School of Medicine, Palo Alto CA 94305, USA.
Flynn E; Orthopaedic Research Laboratory, Boston Children's Hospital, Boston MA 02115, USA.
Wu JY; Department of Medicine/Endocrinology, Stanford University School of Medicine, Palo Alto CA 94305, USA.
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Źródło:
Biology open [Biol Open] 2024 Jan 15; Vol. 13 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage*
Embryo, Mammalian*
Ribs*/abnormalities
Intracellular Signaling Peptides and Proteins*/genetics
Membrane Proteins*/genetics
Animals ; Mice ; Epigenomics ; Mutation ; Receptors, Notch
Czasopismo naukowe
Tytuł:
Embryo-maternal communication mediated by extracellular vesicles in the early stages of embryonic development is modified by in vitro conditions.
Autorzy:
Aguilera C; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Wong YS; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Gutierrez-Reinoso MA; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Velásquez AE; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Melo-Báez B; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Cabezas J; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Caamaño D; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Navarrete F; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Castro FO; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile.
Rodriguez-Alvarez LL; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, Chillan, Chile. Electronic address: .
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Źródło:
Theriogenology [Theriogenology] 2024 Jan 15; Vol. 214, pp. 43-56. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*/metabolism
Extracellular Vesicles*/metabolism
Pregnancy ; Female ; Animals ; Cattle ; Blastocyst/physiology ; Embryonic Development ; Communication
Czasopismo naukowe
Tytuł:
eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling.
Autorzy:
Eley L; Bioscience Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
Richardson RV; Bioscience Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
Alqahtani A; Bioscience Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
Chaudhry B; Bioscience Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
Henderson DJ; Bioscience Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.
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Źródło:
Disease models & mechanisms [Dis Model Mech] 2024 Jan 01; Vol. 17 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Defects, Congenital*
Hypertension*
Embryo, Mammalian*
Mice ; Animals ; Humans ; Heart ; Nitric Oxide Synthase Type III/metabolism ; Aorta/metabolism ; Mice, Knockout ; Cardiomegaly
Czasopismo naukowe
Tytuł:
Automated, High-Throughput Phenotypic Screening and Analysis Platform to Study Pre- and Post-Implantation Morphogenesis in Stem Cell-Derived Embryo-Like Structures.
Autorzy:
Shankar V; MERLN Institute for Technology-Inspired Regenerative Medicine, Department for Instructive Biomaterials Engineering (IBE), Maastricht University, Maastricht, 6229ET, The Netherlands.
van Blitterswijk C; MERLN Institute for Technology-Inspired Regenerative Medicine, Department for Instructive Biomaterials Engineering (IBE), Maastricht University, Maastricht, 6229ET, The Netherlands.
Vrij E; MERLN Institute for Technology-Inspired Regenerative Medicine, Department for Instructive Biomaterials Engineering (IBE), Maastricht University, Maastricht, 6229ET, The Netherlands.
Giselbrecht S; MERLN Institute for Technology-Inspired Regenerative Medicine, Department for Instructive Biomaterials Engineering (IBE), Maastricht University, Maastricht, 6229ET, The Netherlands.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jan; Vol. 11 (4), pp. e2304987. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*
Endoderm*/metabolism
Pregnancy ; Female ; Humans ; Cell Differentiation ; Morphogenesis ; Embryonic Stem Cells
Czasopismo naukowe
Tytuł:
Why study human embryo development?
Autorzy:
Rossant J; The Gairdner Foundation and the Hospital for Sick Children, University of Toronto, MaRS Centre, Heritage Building, 101 College Street, Suite 335, Toronto, Ontario, M5G 1L7, Canada. Electronic address: .
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Źródło:
Developmental biology [Dev Biol] 2024 May; Vol. 509, pp. 43-50. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Embryonic Development*
Embryo, Mammalian*
Humans ; Pregnancy ; Adult ; Female ; Animals ; Mice ; Blastocyst ; Stem Cells
Czasopismo naukowe
Tytuł:
Optimized protocol for whole-mount RNA fluorescent in situ hybridization using oxidation-mediated autofluorescence reduction on mouse embryos.
Autorzy:
Morabito A; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
Malkmus J; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
Pancho A; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
Zuniga A; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
Zeller R; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland.
Sheth R; Developmental Genetics, Department of Biomedicine, University of Basel, 4058 Basel, Switzerland. Electronic address: .
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Źródło:
STAR protocols [STAR Protoc] 2023 Dec 15; Vol. 4 (4), pp. 102603. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
RNA*/metabolism
Embryo, Mammalian*/diagnostic imaging
Embryo, Mammalian*/metabolism
Animals ; Mice ; In Situ Hybridization, Fluorescence/methods ; Fluorescent Antibody Technique
Czasopismo naukowe
Tytuł:
Embryo-scale reverse genetics at single-cell resolution.
Autorzy:
Saunders LM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Srivatsan SR; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Duran M; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Dorrity MW; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Ewing B; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Linbo TH; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
Raible DW; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Department of Biological Structure, University of Washington, Seattle, WA, USA.
Moens CB; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Kimelman D; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Department of Biochemistry, University of Washington, Seattle, WA, USA. .
Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA. .; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA. .
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Źródło:
Nature [Nature] 2023 Nov; Vol. 623 (7988), pp. 782-791. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Embryo, Mammalian*/embryology
Embryo, Mammalian*/metabolism
Reverse Genetics*/methods
Zebrafish*/embryology
Zebrafish*/genetics
Single-Cell Analysis*/methods
Animals ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Transcriptome/genetics ; Mutation ; Notochord/cytology ; Notochord/embryology
Czasopismo naukowe
Tytuł:
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
Autorzy:
Huang X; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Henck J; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Qiu C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Sreenivasan VKA; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.
Balachandran S; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany.
Amarie OV; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Hrabě de Angelis M; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.; Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universität München, Freising, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Behncke RY; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Chan WL; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Despang A; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Dickel DE; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Duran M; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Feuchtinger A; Core Facility Pathology & Tissue Analytics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Fuchs H; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Gailus-Durner V; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Haag N; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Hägerling R; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Hansmeier N; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Hennig F; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Marshall C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.
Rajderkar S; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Ringel A; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.
Robson M; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Saunders LM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
da Silva-Buttkus P; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Spielmann N; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany.
Srivatsan SR; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Ulferts S; Institute of Medical Genetics and Human Genetics of the Charité, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Wittler L; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Zhu Y; German Center for Diabetes Research (DZD), Neuherberg, Germany.
Kalscheuer VM; Max Planck Institute for Molecular Genetics, Berlin, Germany.
Ibrahim DM; Max Planck Institute for Molecular Genetics, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BCRT, Berlin, Germany.
Kurth I; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Kornak U; Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany.
Visel A; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Pennacchio LA; Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Beier DR; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.; Center for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
Cao J; Laboratory of Single-Cell Genomics and Population Dynamics, The Rockefeller University, New York, NY, USA. .
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA. .; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA, USA. .; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA. .; Howard Hughes Medical Institute, Seattle, WA, USA. .
Spielmann M; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck & Kiel University, Lübeck, Germany. .; Max Planck Institute for Molecular Genetics, Berlin, Germany. .; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Lübeck/Kiel, Lübeck, Germany. .
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Źródło:
Nature [Nature] 2023 Nov; Vol. 623 (7988), pp. 772-781. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Developmental Disabilities*/genetics
Developmental Disabilities*/pathology
Embryo, Mammalian*/metabolism
Embryo, Mammalian*/pathology
Mutation*
Phenotype*
Single-Cell Gene Expression Analysis*
Animals ; Mice ; Cell Nucleus/genetics ; Gain of Function Mutation ; Genotype ; Loss of Function Mutation ; Models, Genetic ; Disease Models, Animal
Czasopismo naukowe

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