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Wyszukujesz frazę ""Endothelin-1"" wg kryterium: Temat


Tytuł :
Down-regulation of EDN1 gene expression by circulating miR-206 is associated with risk of preeclampsia.
Autorzy :
Sheng C; Department of obstetrics and gynecology, Wenling Hospital of Traditional Chinese Medicine.
Zhao Y; Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Zhejiang Chinese Medical University.
Zhu L; Department of Gynaecology and Obstetrics, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang, PR China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 May 29; Vol. 99 (22), pp. e20319.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelin-1/*blood
MicroRNAs/*blood
Pre-Eclampsia/*blood
Adult ; Down-Regulation ; Endothelin-1/genetics ; Enzyme-Linked Immunosorbent Assay ; Female ; Gene Expression ; Humans ; Pregnancy ; ROC Curve ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone.
Autorzy :
Adams KL; Center for Neuroscience Research, Children's National Research Institute, Children's National Hospital, Washington, DC, 20010, USA.
Riparini G; Center for Neuroscience Research, Children's National Research Institute, Children's National Hospital, Washington, DC, 20010, USA.; Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Urbino, Italy.
Banerjee P; Children's National Research Institute Bioinformatics Unit, Children's National Hospital, Washington, DC, 20010, USA.
Breur M; Department of Child Neurology, VU University Medical Center, Amsterdam, The Netherlands.
Bugiani M; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Gallo V; Center for Neuroscience Research, Children's National Research Institute, Children's National Hospital, Washington, DC, 20010, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 May 01; Vol. 11 (1), pp. 2138. Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelin-1/*metabolism
Nervous System/*cytology
Nervous System/*metabolism
Neuroglia/*cytology
Neuroglia/*metabolism
Stem Cell Niche/*physiology
Animals ; Cell Proliferation/physiology ; Endothelin-1/genetics ; Humans ; Immunohistochemistry ; In Situ Hybridization ; Mice ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Receptors, Notch/metabolism ; Signal Transduction/physiology ; Stem Cell Niche/genetics
Czasopismo naukowe
Tytuł :
Downregulation of endothelial nitric oxide synthase (eNOS) and endothelin-1 (ET-1) in a co-culture system with human stimulated X-linked CGD neutrophils.
Autorzy :
Nakamura-Utsunomiya A; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Tsumura M; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Okada S; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Kawaguchi H; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Kobayashi M; Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
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Źródło :
PloS one [PLoS One] 2020 Apr 06; Vol. 15 (4), pp. e0230665. Date of Electronic Publication: 2020 Apr 06 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Coculture Techniques*
Down-Regulation*
Endothelin-1/*metabolism
Granulomatous Disease, Chronic/*metabolism
Neutrophils/*cytology
Neutrophils/*metabolism
Nitric Oxide Synthase Type III/*metabolism
Adolescent ; Case-Control Studies ; Endothelin-1/genetics ; Female ; Granulomatous Disease, Chronic/genetics ; Granulomatous Disease, Chronic/immunology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Hydrogen Peroxide/metabolism ; Male ; Nitric Oxide Synthase Type III/genetics ; Phosphorylation ; RNA, Messenger/genetics ; Transcription Factor RelA/metabolism
Czasopismo naukowe
Tytuł :
Activated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension.
Autorzy :
Bochenek ML; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
Leidinger C; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.
Rosinus NS; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
Gogiraju R; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
Guth S; Thoracic Surgery, Kerckhoff Clinic, Bad Nauheim, Germany (S.G., E.M.).
Hobohm L; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.
Jurk K; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.
Mayer E; Thoracic Surgery, Kerckhoff Clinic, Bad Nauheim, Germany (S.G., E.M.).; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
Münzel T; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
Lankeit M; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.; Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité -University Medicine, Berlin, Germany (M.L.).
Bosmann M; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.; Department of Medicine, Boston University School of Medicine, MA (M.B.).
Konstantinides S; Center for Thrombosis and Hemostasis (M.L.B., L.H., K.J., M.L., M.B., S.K.), University Medical Center Mainz, Germany.; Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece (S.K.).
Schäfer K; From the Center for Cardiology, Cardiology I (M.L.B., C.L., N.S.R., R.G., L.H., T.M., K.S.), University Medical Center Mainz, Germany.; German Center for Cardiovascular Research (DZHK e.V.; RheinMain) (M.L.B., N.S.R., R.G., E.M., T.M., K.S.).
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Źródło :
Circulation research [Circ Res] 2020 Jan 17; Vol. 126 (2), pp. 162-181. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelin-1/*metabolism
Hypertension, Pulmonary/*metabolism
Receptor, Transforming Growth Factor-beta Type II/*genetics
Transforming Growth Factor beta/*metabolism
Venous Thrombosis/*metabolism
Activin Receptors, Type II/metabolism ; Aged ; Aged, 80 and over ; Animals ; Blood Platelets/metabolism ; Endothelin-1/genetics ; Female ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Hypertension, Pulmonary/etiology ; Male ; Mice ; Mutation ; Receptor, Transforming Growth Factor-beta Type I/metabolism ; Receptor, Transforming Growth Factor-beta Type II/metabolism ; Signal Transduction ; Venae Cavae/metabolism ; Venae Cavae/pathology ; Venous Thrombosis/complications
Czasopismo naukowe
Tytuł :
Endothelin-1 Level in Patients with Simple Renal Cyst.
Autorzy :
Çalişkan S; Istanbul Reyap Hospital, İstanbul, Turkey.
Sungur M; Hitit University, Çorum Erol Olçok Training and Research Hospital, Çorum, Turkey.
Eser B; Hitit University, Çorum Erol Olçok Training and Research Hospital, Çorum, Turkey.
Kanbay M; Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
Kocan H; Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
Topaktas R; Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
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Źródło :
Folia medica [Folia Med (Plovdiv)] 2019 Dec 31; Vol. 61 (4), pp. 545-550.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelin-1/*blood
Polycystic Kidney, Autosomal Dominant/*metabolism
Aged ; Endothelin-1/urine ; Female ; Humans ; Laparoscopy ; Male ; Middle Aged ; Polycystic Kidney, Autosomal Dominant/etiology ; Polycystic Kidney, Autosomal Dominant/surgery ; Prospective Studies
Czasopismo naukowe
Tytuł :
Endothelin-1-Induced Ischemic Damage and Functional Impairment Is Mediated Primarily by NR2B-Containing NMDA Receptors.
Autorzy :
Hume AW; Department of Biomedical Sciences, University of Prince Edward Island, 550 University Avenue, Charlottetown, PEI, C1A 4P3, Canada.
Tasker RA; Department of Biomedical Sciences, University of Prince Edward Island, 550 University Avenue, Charlottetown, PEI, C1A 4P3, Canada. .; Translational Neuropsychiatry Unit, Clinical Medicine, Aarhus University, Aarhus, Denmark. .
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Źródło :
Neurotoxicity research [Neurotox Res] 2020 Feb; Vol. 37 (2), pp. 349-355. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*chemically induced
Endothelin-1/*toxicity
Psychomotor Performance/*drug effects
Psychomotor Performance/*physiology
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Receptors, N-Methyl-D-Aspartate/*physiology
Animals ; Brain Ischemia/physiopathology ; Dizocilpine Maleate/administration & dosage ; Endothelin-1/administration & dosage ; Excitatory Amino Acid Antagonists/administration & dosage ; Forelimb/drug effects ; Forelimb/physiology ; Male ; Microinjections/methods ; Phenols/administration & dosage ; Piperidines/administration & dosage ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Interaction between PGI 2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients.
Autorzy :
Ozen G; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Istanbul University, Faculty of Pharmacy, Department of Pharmacology, Istanbul 34116, Turkey.
Benyahia C; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France.
Amgoud Y; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France.
Patel J; Institute of Cardiovascular Science, University College London, London WC1E 6JF, UK.
Abdelazeem H; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France.
Bouhadoun A; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France.
Yung S; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France.
Li F; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France.
Mahieddine Y; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France.
Silverstein AM; United Therapeutics Corporation, Research Triangle Park, NC 27709, USA.
Castier Y; Hôpital Bichat-Claude Bernard, AP-HP, 75018 Paris, France.
Cazes A; Hôpital Bichat-Claude Bernard, AP-HP, 75018 Paris, France.
Longrois D; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Hôpital Bichat-Claude Bernard, AP-HP, 75018 Paris, France.
Clapp LH; Institute of Cardiovascular Science, University College London, London WC1E 6JF, UK.
Norel X; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Paris 13 University, 93430 Villetaneuse, France. Electronic address: .
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Źródło :
Prostaglandins & other lipid mediators [Prostaglandins Other Lipid Mediat] 2020 Feb; Vol. 146, pp. 106388. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Endothelin-1/*metabolism
Epoprostenol/*metabolism
Hypertension, Pulmonary/*metabolism
Muscle, Smooth, Vascular/*metabolism
Aged ; Endothelin-1/pharmacology ; Epoprostenol/pharmacology ; Female ; Humans ; Hypertension, Pulmonary/pathology ; Male ; Middle Aged ; Muscle, Smooth, Vascular/pathology ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Pulmonary Veins/metabolism ; Pulmonary Veins/pathology ; Receptor, Endothelin A/metabolism ; Receptor, Endothelin B/metabolism
Czasopismo naukowe
Tytuł :
Linking regulation of nitric oxide to endothelin-1: The Yin and Yang of vascular tone in the atherosclerotic plaque.
Autorzy :
Gupta RM; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Genetics, Brigham and Women's Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard University, Cambridge, MA, USA. Electronic address: .
Libby P; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Barton M; Molecular Internal Medicine, University of Zurich, Zürich, Switzerland; Andreas Grüntzig Foundation, Zürich, Switzerland. Electronic address: .
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Źródło :
Atherosclerosis [Atherosclerosis] 2020 Jan; Vol. 292, pp. 201-203. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Endothelin-1*
Plaque, Atherosclerotic*
Arginase ; Endothelium, Vascular ; Humans ; Nitric Oxide
Opinia redakcyjna
Tytuł :
Free-energy landscape of molecular interactions between endothelin 1 and human endothelin type B receptor: fly-casting mechanism.
Autorzy :
Higo J; Graduate School of Simulation Studies, University of Hyogo, 7-1-28 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.; Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Osaka, Suita 565-0871, Japan.
Kasahara K; College of Life Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Shiga, Kusatsu 525-8577, Japan.
Wada M; Technology Research Association for Next Generation Natural Products Chemistry, 2-3-26, Aomi, Tokyo, Koto-ku 135-0064, Japan.
Dasgupta B; Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Osaka, Suita 565-0871, Japan.
Kamiya N; Graduate School of Simulation Studies, University of Hyogo, 7-1-28 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.; Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Osaka, Suita 565-0871, Japan.
Hayami T; Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Osaka, Suita 565-0871, Japan.
Fukuda I; Graduate School of Simulation Studies, University of Hyogo, 7-1-28 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.
Fukunishi Y; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), 2-3-26, Aomi, Tokyo, Koto-ku 135-0064, Japan.
Nakamura H; Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Osaka, Suita 565-0871, Japan.
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Źródło :
Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2019 Dec 31; Vol. 32 (7), pp. 297-308.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelin-1/*metabolism
Receptor, Endothelin B/*metabolism
Binding Sites ; Endothelin-1/chemistry ; Humans ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation ; Receptor, Endothelin B/chemistry ; Thermodynamics
Czasopismo naukowe
Tytuł :
Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise.
Autorzy :
Jurrissen TJ; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri.
Grunewald ZI; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri.
Woodford ML; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri.
Winn NC; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee.
Ball JR; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.
Smith TN; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.
Wheeler AA; Department of Surgery, University of Missouri, Columbia, Missouri.
Rawlings AL; Department of Surgery, University of Missouri, Columbia, Missouri.
Staveley-O'Carroll KF; Department of Surgery, University of Missouri, Columbia, Missouri.
Ji Y; Department of Medical Pharmacology and Physiology, University of Missouri School of Medicine, University of Missouri, Columbia, Missouri.
Fay WP; Department of Medical Pharmacology and Physiology, University of Missouri School of Medicine, University of Missouri, Columbia, Missouri.; Department of Medicine, University of Missouri, Columbia, Missouri.; Research Service, Harry S. Truman Memorial Veterans Hospital, University of Missouri, Columbia, Missouri.
Paradis P; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC, Canada.
Schiffrin EL; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC, Canada.; Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC, Canada.
Vieira-Potter VJ; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.
Fadel PJ; Department of Kinesiology, University of Texas at Arlington, Arlington, Texas.
Martinez-Lemus LA; Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri.; Department of Medical Pharmacology and Physiology, University of Missouri School of Medicine, University of Missouri, Columbia, Missouri.
Padilla J; Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2019 Sep 01; Vol. 317 (3), pp. E548-E558. Date of Electronic Publication: 2019 Jul 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Endothelin-1/*metabolism
Glucose Intolerance/*metabolism
Inflammation/*pathology
Intra-Abdominal Fat/*pathology
Physical Conditioning, Animal/*physiology
Animals ; Body Mass Index ; Endothelin-1/antagonists & inhibitors ; Endothelin-1/genetics ; Exercise/physiology ; Female ; Gene Expression ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Obese ; Obesity/pathology ; Running
Czasopismo naukowe
Tytuł :
Local renal complement activation mediates immune kidney injury by inducing endothelin-1 signalling and inflammation in trichloroethylene-sensitised mice.
Autorzy :
Wang G; Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China; Department of Nutrition and Food Hygiene, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Zhang J; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Dai Y; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Xu Q; Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Zhu Q; Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 15; Vol. 333, pp. 130-139. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Complement Activation/*immunology
Endothelin-1/*metabolism
Hypersensitivity/*metabolism
Kidney/*drug effects
Renal Insufficiency/*metabolism
Trichloroethylene/*toxicity
Animals ; Complement Activation/drug effects ; Disease Models, Animal ; Female ; Hypersensitivity/immunology ; Inflammation ; Kidney/immunology ; Kidney/metabolism ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/immunology ; Mice ; Mice, Inbred BALB C ; NF-kappa B/drug effects ; NF-kappa B/immunology ; Renal Insufficiency/chemically induced ; Renal Insufficiency/immunology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Endothelin converting enzyme-1 (ECE-1) deletion in association with Endothelin-1 downregulation ameliorates kidney fibrosis in mice.
Autorzy :
Arfian N; Department of Anatomy, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. Electronic address: .
Suzuki Y; Laboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, Kobe, Japan. Electronic address: .
Hartopo AB; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. Electronic address: .
Anggorowati N; Department of Anatomical Pathology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. Electronic address: .
Nugrahaningsih DAA; Department of Pharmacology and Therapy, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. Electronic address: .
Emoto N; Laboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, Kobe, Japan; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118223. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation/*physiology
Endothelin-1/*metabolism
Endothelin-Converting Enzymes/*deficiency
Kidney/*metabolism
Animals ; Endothelin-Converting Enzymes/genetics ; Fibrosis ; Kidney/pathology ; Male ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł :
The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver.
Autorzy :
Klindt C; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital, Medical Faculty of Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Reich M; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital, Medical Faculty of Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Hellwig B; Department of Statistics, TU Dortmund University, 44221 Dortmund, Germany.
Stindt J; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital, Medical Faculty of Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Rahnenführer J; Department of Statistics, TU Dortmund University, 44221 Dortmund, Germany.
Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors, TU Dortmund, 44139 Dortmund, Germany.
Köhrer K; Genomics and Transcriptomics Laboratory, Biologisch-Medizinisches-Forschungszentrum (BMFZ), Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Schoonjans K; Laboratory of Metabolic Signaling, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Häussinger D; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital, Medical Faculty of Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Keitel V; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital, Medical Faculty of Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
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Źródło :
Cells [Cells] 2019 Nov 19; Vol. 8 (11). Date of Electronic Publication: 2019 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Endothelin-1/*metabolism
Liver/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Biomarkers ; Endothelial Cells/metabolism ; Endothelin-1/genetics ; Female ; Gene Expression ; Gene Expression Profiling ; Hepatic Stellate Cells/metabolism ; Mice ; Mice, Knockout ; Mice, Transgenic ; Receptors, G-Protein-Coupled/genetics
Czasopismo naukowe
Tytuł :
Endothelin-1 in hypertensive patients with ischemic heart disease.
Autorzy :
Moroni C; Cardiovascular Sciences Department, Sapienza University, Rome, Italy. .
Tolone S; Cardiovascular Sciences Department, Sapienza University, Rome, Italy.
Bondanini F; Laboratory Medicine, S. Eugenio Hospital, Rome, Italy.
Schillaci O; Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
Affricano C; Statistics, Sapienza University, Rome, Italy.
Cassone R; Cardiovascular Sciences Department, Sapienza University, Rome, Italy.
Gaspardone A; U.O.C. di Cardiologia, S. Eugenio Hospital, Rome, Italy.
Gaudio C; Cardiovascular Sciences Department, Sapienza University, Rome, Italy.
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Źródło :
Internal and emergency medicine [Intern Emerg Med] 2019 Oct; Vol. 14 (7), pp. 1119-1124. Date of Electronic Publication: 2019 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelin-1/*analysis
Hypertension/*complications
Myocardial Ischemia/*etiology
Adult ; Dipyridamole/therapeutic use ; Echocardiography/methods ; Endothelin-1/blood ; Female ; Humans ; Hypertension/blood ; Hypertension/physiopathology ; Male ; Middle Aged ; Myocardial Ischemia/blood ; Myocardial Ischemia/physiopathology ; Myocardial Perfusion Imaging/methods ; Retrospective Studies
Czasopismo naukowe
Tytuł :
The effect of nicorandil in patients with cardiac syndrome X: A meta-analysis of randomized controlled trials.
Autorzy :
Jia Q; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.; Graduate School, Beijing University of Chinese Medicine, China.
Shi S; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.; Graduate School, Beijing University of Chinese Medicine, China.
Yuan G; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.
Shi J; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.
Shi S; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.
Wei Y; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.
Hu Y; Department of cardiovascular, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Sep 11; Vol. 99 (37), pp. e22167.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Microvascular Angina/*drug therapy
Nicorandil/*therapeutic use
Vasodilator Agents/*therapeutic use
Electrocardiography ; Endothelin-1/blood ; Endothelium, Vascular/drug effects ; Exercise Test ; Humans ; Nitric Oxide/blood ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
The Expression of BNP, ET-1, and TGF-β1 in Myocardium of Rats with Ventricular Arrhythmias.
Autorzy :
Tian M; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Xiao Y; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Xue J; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Zhang Y; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Jia Y; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Luo X; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Wang T; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Zhu B; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
Cao Z; Department of Forensic Pathology, School of Forensic Medicine, China Medical University No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, Liaoning Province, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Nov 21; Vol. 20 (23). Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article
MeSH Terms :
Arrhythmias, Cardiac/*genetics
Endothelin-1/*genetics
Myocardium/*metabolism
Natriuretic Peptide, Brain/*genetics
Transforming Growth Factor beta1/*genetics
Animals ; Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/metabolism ; Benzamides/pharmacology ; Death, Sudden, Cardiac/etiology ; Dioxoles/pharmacology ; Endothelin Receptor Antagonists/pharmacology ; Endothelin-1/metabolism ; Gene Expression ; Male ; Myocardium/pathology ; Natriuretic Peptide, Brain/metabolism ; Oligopeptides/pharmacology ; Rats, Sprague-Dawley ; Receptors, Endothelin/metabolism ; Receptors, Transforming Growth Factor beta/antagonists & inhibitors ; Receptors, Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Trapping endothelin-1 to hunt down cardiovascular disease?
Autorzy :
Wernly B; Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.
Jung C; Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Duesseldorf, Germany. Electronic address: .
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Źródło :
Drug discovery today [Drug Discov Today] 2019 Nov; Vol. 24 (11), pp. 2108-2110. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Editorial
MeSH Terms :
Cardiovascular Diseases/*drug therapy
Cardiovascular Diseases/*metabolism
Endothelin Receptor Antagonists/*therapeutic use
Endothelin-1/*antagonists & inhibitors
Receptor, Endothelin A/*metabolism
Endothelin Receptor Antagonists/administration & dosage ; Endothelin Receptor Antagonists/adverse effects ; Endothelin-1/genetics ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Humans ; Receptor, Endothelin A/genetics
Opinia redakcyjna
Tytuł :
Modulating effects of preconditioning exercise in the expression of ET-1 and BNP via HIF-1α in ischemically injured brain.
Autorzy :
Wang H; Department of Histology& Embryology, Basic Medicine School, Dali University, Yunnan, China.
Niu F; Department of Rehabilitation, Jinshan Hospital, Fudan University, Shanghai, China.
Fan W; Central Laboratory, Jinshan Hospital, Fudan University, No.1508, Longhang Road, Jinshan district, Shanghai, 201508, China.
Shi J; Central Laboratory, Jinshan Hospital, Fudan University, No.1508, Longhang Road, Jinshan district, Shanghai, 201508, China.
Zhang J; Central Laboratory, Jinshan Hospital, Fudan University, No.1508, Longhang Road, Jinshan district, Shanghai, 201508, China.
Li B; Central Laboratory, Jinshan Hospital, Fudan University, No.1508, Longhang Road, Jinshan district, Shanghai, 201508, China. .
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Źródło :
Metabolic brain disease [Metab Brain Dis] 2019 Oct; Vol. 34 (5), pp. 1299-1311. Date of Electronic Publication: 2019 Jun 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*metabolism
Corpus Striatum/*metabolism
Endothelin-1/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Ischemic Preconditioning/*methods
Natriuretic Peptide, Brain/*metabolism
Animals ; Endothelin-1/blood ; Hypoxia-Inducible Factor 1, alpha Subunit/blood ; Male ; Physical Conditioning, Animal/physiology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Adrenomedullin and endothelin-1: Promising biomarkers of endothelial function, but not ready for prime time.
Autorzy :
Parikh RV; Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Fearon WF; Division of Cardiovascular Medicine and Stanford Cardiovascular Institute, Stanford University School, Stanford, CA, United States of America. Electronic address: .
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Źródło :
International journal of cardiology [Int J Cardiol] 2019 Sep 15; Vol. 291, pp. 175-176. Date of Electronic Publication: 2019 May 23.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Adrenomedullin*
Endothelin-1*
Biomarkers ; Coronary Vessels ; Humans
Opinia redakcyjna
Tytuł :
Increased Levels of Endothelin-1 in Cerebrospinal Fluid Are a Marker of Poor Visual Recovery after Optic Neuritis in Multiple Sclerosis Patients.
Autorzy :
Castellazzi M; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.; Interdepartmental Research Center for the Study of Multiple Sclerosis and Inflammatory and Degenerative Diseases of the Nervous System, University of Ferrara, Ferrara, Italy.; Department of Neuroscience and Rehabilitation, S. Anna University Hospital, Ferrara, Italy.
Lamberti G; Department of Specialty Surgery, S. Anna University Hospital, Ferrara, Italy.
Resi MV; School of Medicine, University of Ferrara, Italy.
Baldi E; Interdepartmental Research Center for the Study of Multiple Sclerosis and Inflammatory and Degenerative Diseases of the Nervous System, University of Ferrara, Ferrara, Italy.; Department of Neuroscience and Rehabilitation, S. Anna University Hospital, Ferrara, Italy.
Caniatti LM; Interdepartmental Research Center for the Study of Multiple Sclerosis and Inflammatory and Degenerative Diseases of the Nervous System, University of Ferrara, Ferrara, Italy.; Department of Neuroscience and Rehabilitation, S. Anna University Hospital, Ferrara, Italy.
Galante G; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
Perri P; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.; Department of Specialty Surgery, S. Anna University Hospital, Ferrara, Italy.
Pugliatti M; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.; Interdepartmental Research Center for the Study of Multiple Sclerosis and Inflammatory and Degenerative Diseases of the Nervous System, University of Ferrara, Ferrara, Italy.; Department of Neuroscience and Rehabilitation, S. Anna University Hospital, Ferrara, Italy.
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Źródło :
Disease markers [Dis Markers] 2019 Sep 10; Vol. 2019, pp. 9320791. Date of Electronic Publication: 2019 Sep 10 (Print Publication: 2019).
Typ publikacji :
Journal Article
MeSH Terms :
Endothelin-1/*cerebrospinal fluid
Multiple Sclerosis/*cerebrospinal fluid
Optic Nerve/*metabolism
Optic Neuritis/*cerebrospinal fluid
Adult ; Astrocytes/metabolism ; Astrocytes/pathology ; Biomarkers/blood ; Biomarkers/cerebrospinal fluid ; Cross-Sectional Studies ; Endothelin-1/blood ; Female ; Humans ; Male ; Middle Aged ; Multiple Sclerosis/blood ; Multiple Sclerosis/diagnostic imaging ; Multiple Sclerosis/physiopathology ; Optic Nerve/diagnostic imaging ; Optic Neuritis/blood ; Optic Neuritis/diagnostic imaging ; Optic Neuritis/physiopathology ; Severity of Illness Index ; Tomography, Optical Coherence ; White Matter/diagnostic imaging ; White Matter/metabolism
Czasopismo naukowe

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