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Wyszukujesz frazę ""Entorhinal Cortex"" wg kryterium: Temat


Tytuł :
Scavenging Tumor Necrosis Factor α Does Not Affect Inhibition of Dentate Granule Cells Following In Vitro Entorhinal Cortex Lesion.
Autorzy :
Kleidonas D; Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, 79104 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
Vlachos A; Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.; Center Brain Links Brain Tools, University of Freiburg, 79110 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
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Źródło :
Cells [Cells] 2021 Nov 19; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dentate Gyrus/*pathology
Entorhinal Cortex/*metabolism
Entorhinal Cortex/*pathology
Synapses/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Dentate Gyrus/physiopathology ; Entorhinal Cortex/physiopathology ; Gene Expression Regulation ; Mice, Inbred C57BL ; Microglia/metabolism ; Receptors, Tumor Necrosis Factor/metabolism ; Solubility ; Synaptic Transmission ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł :
Photostimulation activates fast-spiking interneurons and pyramidal cells in the entorhinal cortex of Thy1-ChR2-YFP line 18 mice.
Autorzy :
Proskurina EY; Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS, 44, Toreza Prospekt, St. Petersburg, 194223, Russia; Almazov National Medical Research Centre, Institute of Experimental Medicine, 2 Akkuratova Street, St. Petersburg, 197341, Russia. Electronic address: .
Zaitsev AV; Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS, 44, Toreza Prospekt, St. Petersburg, 194223, Russia. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 26; Vol. 580, pp. 87-92. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex/*physiology
Interneurons/*physiology
Mice/*physiology
Pyramidal Cells/*physiology
Animals ; Bacterial Proteins/genetics ; Carrier Proteins/genetics ; Entorhinal Cortex/radiation effects ; Interneurons/radiation effects ; Light ; Luminescent Proteins/genetics ; Mice/genetics ; Mice, Transgenic ; Optogenetics ; Pyramidal Cells/radiation effects ; Thy-1 Antigens/genetics
Czasopismo naukowe
Tytuł :
Distal CA1 Maintains a More Coherent Spatial Representation than Proximal CA1 When Local and Global Cues Conflict.
Autorzy :
Deshmukh SS; Centre for Neuroscience, Indian Institute of Science, Bangalore, India 560012 .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Nov 24; Vol. 41 (47), pp. 9767-9781. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cues*
CA1 Region, Hippocampal/*physiology
Entorhinal Cortex/*physiology
Neural Pathways/*physiology
Spatial Navigation/*physiology
Animals ; Entorhinal Cortex/anatomy & histology ; Male ; Memory, Episodic ; Rats ; Rats, Long-Evans
Czasopismo naukowe
Tytuł :
Multiple Sessions of Entorhinal Cortex Deep Brain Stimulation in C57BL/6J Mice Increases Exploratory Behavior and Hippocampal Neurogenesis .
Autorzy :
Sun YW
Luo YP
Zheng XL
Wu XY
Wen HZ
Hou WS
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Źródło :
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2021 Nov; Vol. 2021, pp. 6390-6393.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Deep Brain Stimulation*
Entorhinal Cortex*
Animals ; Exploratory Behavior ; Hippocampus ; Male ; Mice ; Mice, Inbred C57BL ; Neurogenesis
Czasopismo naukowe
Tytuł :
Irregular distribution of grid cell firing fields in rats exploring a 3D volumetric space.
Autorzy :
Grieves RM; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK. .; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA. .
Jedidi-Ayoub S; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK.
Mishchanchuk K; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK.
Liu A; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK.
Renaudineau S; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK.
Duvelle É; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK.; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA.
Jeffery KJ; Department of Experimental Psychology, Institute of Behavioural Neuroscience, University College London, London, UK. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2021 Nov; Vol. 24 (11), pp. 1567-1573. Date of Electronic Publication: 2021 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Neurological*
Action Potentials/*physiology
Entorhinal Cortex/*physiology
Exploratory Behavior/*physiology
Grid Cells/*physiology
Space Perception/*physiology
Animals ; Entorhinal Cortex/cytology ; Male ; Rats
Czasopismo naukowe
Tytuł :
Precisely timed theta oscillations are selectively required during the encoding phase of memory.
Autorzy :
Quirk CR; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Zutshi I; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Srikanth S; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Fu ML; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Devico Marciano N; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Wright MK; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Parsey DF; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Liu S; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Siretskiy RE; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Huynh TL; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Leutgeb JK; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA.
Leutgeb S; Neurobiology Section and Center for Neural Circuits and Behavior, University of California, San Diego, La Jolla, CA, USA. .; Kavli Institute for Brain and Mind, University of California, San Diego, La Jolla, CA, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2021 Nov; Vol. 24 (11), pp. 1614-1627. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex/*physiology
Hippocampus/*physiology
Memory/*physiology
Spatial Behavior/*physiology
Theta Rhythm/*physiology
Animals ; Entorhinal Cortex/chemistry ; Hippocampus/chemistry ; Male ; Mice ; Mice, 129 Strain ; Mice, Transgenic ; Optogenetics/methods ; Time Factors
Czasopismo naukowe
Tytuł :
The Entorhinal Cortex and Adult Neurogenesis in Major Depression.
Autorzy :
Kim IB; Department of Psychiatry, Hanyang University Guri Hospital, Guri 11923, Korea.; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Park SC; Department of Psychiatry, Hanyang University Guri Hospital, Guri 11923, Korea.; Department of Psychiatry, Hanyang University College of Medicine, Seoul 04763, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 29; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neurogenesis*
Depressive Disorder, Major/*physiopathology
Entorhinal Cortex/*physiopathology
Hippocampus/*physiopathology
Adult ; Animals ; Cognition ; Depressive Disorder, Major/pathology ; Emotions ; Entorhinal Cortex/pathology ; Hippocampus/pathology ; Humans
Czasopismo naukowe
Tytuł :
The hippocampus converts dynamic entorhinal inputs into stable spatial maps.
Autorzy :
Cholvin T; Institute for Physiology I, University of Freiburg, Medical Faculty, Freiburg 79104, Germany.
Hainmueller T; NYU Neuroscience Institute, 435 East 30th Street, New York, NY 10016, USA.
Bartos M; Institute for Physiology I, University of Freiburg, Medical Faculty, Freiburg 79104, Germany. Electronic address: .
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Źródło :
Neuron [Neuron] 2021 Oct 06; Vol. 109 (19), pp. 3135-3148.e7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex/*physiology
Hippocampus/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; CA1 Region, Hippocampal/physiology ; Calcium Signaling ; Dentate Gyrus/cytology ; Dentate Gyrus/physiology ; Entorhinal Cortex/cytology ; Hippocampus/cytology ; Male ; Mental Recall/physiology ; Mice ; Mice, Inbred C57BL ; Nerve Net/cytology ; Nerve Net/physiology ; Presynaptic Terminals/physiology ; Reproducibility of Results ; Space Perception/physiology ; Virtual Reality
Czasopismo naukowe
Tytuł :
Phoenixin-14 reduces the frequency of interictal-like events in mice brain slices.
Autorzy :
Kalkan ÖF; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey. .
Şahin Z; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey.
Öztürk H; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey.
Keser H; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey.
Aydın-Abidin S; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey.
Abidin İ; Department of Physiology, Faculty of Medicine, Karadeniz Technical University, 61080, Trabzon, Turkey.
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Źródło :
Experimental brain research [Exp Brain Res] 2021 Sep; Vol. 239 (9), pp. 2841-2849. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article
MeSH Terms :
Entorhinal Cortex*
Hippocampus*
4-Aminopyridine/pharmacology ; Animals ; Mice ; Neurons
Czasopismo naukowe
Tytuł :
Anticataleptic activity of nicotine in rats: involvement of the lateral entorhinal cortex.
Autorzy :
Ionov ID; Centre On Theoretical Problems in Physical and Chemical Pharmacology, Russian Academy of Sciences, Leninsky prospect 123-4-63, Moscow, 117513, Russia. .
Pushinskaya II; Timpharm LTD, Moscow, Russia.
Gorev NP; Timpharm LTD, Moscow, Russia.
Frenkel DD; Timpharm LTD, Moscow, Russia.
Severtsev NN; Timpharm LTD, Moscow, Russia.
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2021 Sep; Vol. 238 (9), pp. 2471-2483. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Entorhinal Cortex*
Nicotine*/pharmacology
Animals ; Catalepsy/chemically induced ; Catalepsy/drug therapy ; Dopamine Antagonists ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Gender-Dependent Deregulation of Linear and Circular RNA Variants of HOMER1 in the Entorhinal Cortex of Alzheimer's Disease.
Autorzy :
Urdánoz-Casado A; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.
Sánchez-Ruiz de Gordoa J; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.; Department of Neurology, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Pamplona, 31008 Navarra, Spain.
Robles M; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.
Acha B; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.
Roldan M; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.
Zelaya MV; Department of Pathology, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Pamplona, 31008 Navarra, Spain.
Blanco-Luquin I; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.
Mendioroz M; Neuroepigenetics Laboratory-Navarrabiomed, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Universidad Pública de Navarra (UPNA), Pamplona, 31008 Navarra, Spain.; Department of Neurology, Complejo Hospitalario de Navarra-IdiSNA (Navarra Institute for Health Research), Pamplona, 31008 Navarra, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 26; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Alzheimer Disease/*genetics
Entorhinal Cortex/*metabolism
Homer Scaffolding Proteins/*genetics
RNA, Circular/*genetics
RNA, Messenger/*genetics
Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Biomarkers ; Case-Control Studies ; Down-Regulation ; Entorhinal Cortex/physiopathology ; Female ; Humans ; Male ; Sex Factors
Czasopismo naukowe
Tytuł :
Déjà vu and the entorhinal cortex: dissociating recollective from familiarity disruptions in a single case patient.
Autorzy :
Brandt KR; Department of Psychology, Whitelands College, University of Roehampton, London, UK.
Conway MA; Department of Psychology, City University, London, UK.
James A; Department of Psychology, Whitelands College, University of Roehampton, London, UK.
von Oertzen TJ; Atkinson Morley Neuroscience Centre, St. George's Hospital, London, UK.; Department of Neurology 1, Neuromed Campus, Kepler Universitaetsklinikum, Linz, Austria.
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Źródło :
Memory (Hove, England) [Memory] 2021 Aug; Vol. 29 (7), pp. 859-868. Date of Electronic Publication: 2018 Nov 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex*
Recognition, Psychology*
Humans ; Memory Disorders ; Mental Recall ; Temporal Lobe
Czasopismo naukowe
Tytuł :
Complementary roles of differential medial entorhinal cortex inputs to the hippocampus for the formation and integration of temporal and contextual memory (Systems Neuroscience).
Autorzy :
Marks WD; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yamamoto N; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Kitamura T; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA.
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Źródło :
The European journal of neuroscience [Eur J Neurosci] 2021 Oct; Vol. 54 (8), pp. 6762-6779. Date of Electronic Publication: 2020 May 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Entorhinal Cortex*
Neurosciences*
CA1 Region, Hippocampal ; Hippocampus ; Mental Recall
Czasopismo naukowe
Tytuł :
The grid code for ordered experience.
Autorzy :
Rueckemann JW; Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA, USA.; Washington National Primate Research Center, Seattle, WA, USA.
Sosa M; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, USA.
Giocomo LM; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, USA. .
Buffalo EA; Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA, USA. .; Washington National Primate Research Center, Seattle, WA, USA. .
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Źródło :
Nature reviews. Neuroscience [Nat Rev Neurosci] 2021 Oct; Vol. 22 (10), pp. 637-649. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Entorhinal Cortex/*physiology
Grid Cells/*physiology
Hippocampus/*physiology
Learning/*physiology
Nerve Net/*physiology
Space Perception/*physiology
Animals ; Entorhinal Cortex/cytology ; Hippocampus/cytology ; Humans ; Models, Neurological ; Nerve Net/cytology
Czasopismo naukowe
Tytuł :
A neuromimetic realization of hippocampal CA1 for theta wave generation.
Autorzy :
Salimi-Nezhad N; Medical Biology Research Center, Institute of Health Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Hasanlou M; Faculty of Electrical Engineering, Amirkabir University of Technology, Tehran, Iran.
Amiri M; Medical Technology Research Center, Institute of Health Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium. Electronic address: .
Keliris GA; Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium. Electronic address: .
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Źródło :
Neural networks : the official journal of the International Neural Network Society [Neural Netw] 2021 Oct; Vol. 142, pp. 548-563. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Entorhinal Cortex*
Hippocampus*
Humans ; Interneurons ; Pyramidal Cells ; Theta Rhythm
Czasopismo naukowe
Tytuł :
Neurodegenerative damage reduces firing coherence in a continuous attractor model of grid cells.
Autorzy :
Zhi Y; Physics Department, University of California, Davis, California 95616, USA.
Cox D; Physics Department, University of California, Davis, California 95616, USA.
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Źródło :
Physical review. E [Phys Rev E] 2021 Oct; Vol. 104 (4-1), pp. 044414.
Typ publikacji :
Journal Article
MeSH Terms :
Entorhinal Cortex*
Models, Neurological*
Action Potentials ; Animals ; Cues ; Neural Networks, Computer ; Neurons
Czasopismo naukowe
Tytuł :
Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults.
Autorzy :
Won J; Department of Kinesiology, University of Maryland, College Park, MD.
Alfini AJ; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD.
Smith JC
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Źródło :
Medicine and science in sports and exercise [Med Sci Sports Exerc] 2021 Oct 01; Vol. 53 (10), pp. 2131-2139.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiorespiratory Fitness/*physiology
Entorhinal Cortex/*anatomy & histology
Physical Endurance/*physiology
Sleep/*physiology
Adult ; Cognition/physiology ; Cognitive Dysfunction/physiopathology ; Entorhinal Cortex/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Self Report ; Sleep Initiation and Maintenance Disorders/physiopathology
Czasopismo naukowe
Tytuł :
Lesion of the hippocampus selectively enhances LEC's activity during recognition memory based on familiarity.
Autorzy :
Mahnke L; Functional Architecture of Memory Department, Leibniz-Institute for Neurobiology, 39118, Magdeburg, Germany.
Atucha E; Functional Architecture of Memory Department, Leibniz-Institute for Neurobiology, 39118, Magdeburg, Germany.
Pina-Fernàndez E; Functional Architecture of Memory Department, Leibniz-Institute for Neurobiology, 39118, Magdeburg, Germany.
Kitsukawa T; KOKORO-Biology Group, Osaka University, Osaka, 565-0871, Japan.
Sauvage MM; Functional Architecture of Memory Department, Leibniz-Institute for Neurobiology, 39118, Magdeburg, Germany. .; Functional Neuroplasticity Department, Medical Faculty, Otto von Guericke University, 39120, Magdeburg, Germany. .; Center for Behavioral Brain Sciences, Otto von Guericke University, 39106, Magdeburg, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2021 Sep 27; Vol. 11 (1), pp. 19085. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex/*physiology
Hippocampus/*physiology
Mental Recall/*physiology
Recognition, Psychology/*physiology
Animals ; Behavior Observation Techniques ; Behavior, Animal ; Entorhinal Cortex/pathology ; Hippocampus/pathology ; Hippocampus/surgery ; Male ; Microscopy, Fluorescence ; Models, Animal ; Neural Pathways/physiology ; Odorants ; Perirhinal Cortex/pathology ; Perirhinal Cortex/physiology ; Rats
Czasopismo naukowe
Tytuł :
Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits.
Autorzy :
Palacios-Filardo J; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK.
Udakis M; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK.
Brown GA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.; OMass Therapeutics Ltd, The Schrödinger Building, Oxford, UK.
Tehan BG; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.; OMass Therapeutics Ltd, The Schrödinger Building, Oxford, UK.
Congreve MS; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.
Nathan PJ; Department of Psychiatry, University of Cambridge, Cambridge, UK.
Brown AJH; Sosei Heptares, Steinmetz Building, Granta Park, Great Abingdon, Cambridge, UK.
Mellor JR; Center for Synaptic Plasticity, School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Bristol, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 16; Vol. 12 (1), pp. 5475. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine/*metabolism
CA1 Region, Hippocampal/*physiology
Entorhinal Cortex/*physiology
Excitatory Postsynaptic Potentials/*physiology
Feedback, Physiological/*physiology
Synaptic Transmission/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; Carbachol/pharmacology ; Cholinergic Agonists/pharmacology ; Entorhinal Cortex/cytology ; Excitatory Postsynaptic Potentials/drug effects ; Feedback, Physiological/drug effects ; Interneurons/metabolism ; Interneurons/physiology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Patch-Clamp Techniques ; Pyramidal Cells/metabolism ; Pyramidal Cells/physiology ; Receptor, Muscarinic M3/genetics ; Receptor, Muscarinic M3/metabolism ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice.
Autorzy :
Delpech JC; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.; University of Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286, F-33000 Bordeaux, France.
Pathak D; Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.
Varghese M; Nash Family Department of Neuroscience, Friedman Brain Institute, and Ronald C. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kalavai SV; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
Hays EC; Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.
Hof PR; Nash Family Department of Neuroscience, Friedman Brain Institute, and Ronald C. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Johnson WE; Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA.
Ikezu S; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
Medalla M; Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.; Center for Systems Neuroscience, Boston University, Boston, MA, USA.
Luebke JI; Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.; Center for Systems Neuroscience, Boston University, Boston, MA, USA.
Ikezu T; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.; Center for Systems Neuroscience, Boston University, Boston, MA, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
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Źródło :
Science translational medicine [Sci Transl Med] 2021 Sep 15; Vol. 13 (611), pp. eabe8455. Date of Electronic Publication: 2021 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex*
Hippocampus*
Animals ; Mice ; Neurons
Czasopismo naukowe

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