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Wyszukujesz frazę ""Env"" wg kryterium: Temat


Tytuł:
A Comprehensive Analysis of Human Endogenous Retroviruses HERV-K (HML.2) from Teratocarcinoma Cell Lines and Detection of Viral Cargo in Microvesicles.
Autorzy:
Morozov VA; Department of Infectious Diseases, Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany.
Morozov AV; Laboratory of Regulation of Intracellular Proteolysis, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 17; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, env*
Capsid/*metabolism
Endogenous Retroviruses/*genetics
Endogenous Retroviruses/*metabolism
Extracellular Vesicles/*virology
Gene Products, env/*metabolism
RNA, Viral/*genetics
Teratocarcinoma/*metabolism
Teratocarcinoma/*virology
Viral Envelope/*metabolism
Cell Line, Tumor ; Cell Membrane/metabolism ; Cell Membrane/virology ; Centrifugation, Density Gradient/methods ; Endogenous Retroviruses/isolation & purification ; Gene Products, env/genetics ; HEK293 Cells ; Humans ; Membrane Proteins/metabolism ; RNA, Viral/isolation & purification ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Teratocarcinoma/pathology ; Transfection ; Virus Assembly/genetics
Czasopismo naukowe
Tytuł:
Synonymous Codon Pair Recoding of the HIV-1 env Gene Affects Virus Replication Capacity.
Autorzy:
Jordan-Paiz A; IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), 08916 Badalona, Spain.
Franco S; IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), 08916 Badalona, Spain.
Martinez MA; IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona (UAB), 08916 Badalona, Spain.
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Źródło:
Cells [Cells] 2021 Jun 29; Vol. 10 (7). Date of Electronic Publication: 2021 Jun 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, env*
Codon/*genetics
HIV-1/*genetics
HIV-1/*physiology
Virus Replication/*genetics
Cell Line ; Gene Expression Regulation, Viral ; Humans ; Kinetics ; Mutation/genetics ; Oligodeoxyribonucleotides/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; env Gene Products, Human Immunodeficiency Virus/genetics ; env Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
Tytuł:
Covalent binding of human two-domain CD4 to an HIV-1 subtype C SOSIP.664 trimer modulates its structural dynamics.
Autorzy:
Tumba NL; HIV Pathogenesis Research Unit, Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, Johannesburg, South Africa.
Naicker P; Council for Scientific and Industrial Research, Biosciences, Pretoria, 0001, South Africa.
Stoychev S; Council for Scientific and Industrial Research, Biosciences, Pretoria, 0001, South Africa.
Killick MA; HIV Pathogenesis Research Unit, Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, Johannesburg, South Africa.
Owen GR; HIV Pathogenesis Research Unit, Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, Johannesburg, South Africa. Electronic address: .
Papathanasopoulos MA; HIV Pathogenesis Research Unit, Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, 2193, Johannesburg, South Africa.
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jul 05; Vol. 612, pp. 181-187. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/metabolism
env Gene Products, Human Immunodeficiency Virus*/chemistry
Antibodies, Neutralizing ; CD4 Antigens ; HIV Envelope Protein gp120 ; Humans ; Protein Multimerization
Czasopismo naukowe
Tytuł:
Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2.
Autorzy:
Cale EM; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Driscoll JI; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Lee M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Gorman J; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Lu M; Department of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Cellular and Molecular Biology, University of Texas Health Science Center, Tyler, Texas, USA.
Geng H; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Lai YT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Mothes W; Department of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: .
Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Apr; Vol. 298 (4), pp. 101819. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
HIV-1*/metabolism
env Gene Products, Human Immunodeficiency Virus*/chemistry
env Gene Products, Human Immunodeficiency Virus*/metabolism
Broadly Neutralizing Antibodies/chemistry ; Broadly Neutralizing Antibodies/metabolism ; HIV Antibodies ; Humans ; Protein Conformation
Czasopismo naukowe
Tytuł:
Expression profiles of human endogenous retrovirus (HERV)-K and HERV-R Env proteins in various cancers.
Autorzy:
Ko EJ; Department of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267; Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea.
Song KS; Department of Physiology, Kosin University College of Medicine, Busan 49267, Korea.
Ock MS; Department of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.
Choi YH; Department of Biochemistry, College of Oriental Medicine, Dongeui University, Busan 47227, Korea.
Kim S; Department of Chemistry, College of Natural Sciences, Pusan National University, Busan 46241, Korea.
Kim HS; Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea.
Cha HJ; Department of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.
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Źródło:
BMB reports [BMB Rep] 2021 Jul; Vol. 54 (7), pp. 368-373.
Typ publikacji:
Journal Article
MeSH Terms:
Endogenous Retroviruses/*genetics
Genes, env/*genetics
Neoplasms/*genetics
Endogenous Retroviruses/metabolism ; Gene Expression/genetics ; Gene Expression Profiling/methods ; Gene Products, env/genetics ; Gene Products, env/metabolism ; Humans ; Tissue Array Analysis/methods ; Transcriptome/genetics
Czasopismo naukowe
Tytuł:
Components of a HIV-1 vaccine mediate virus-like particle (VLP)-formation and display of envelope proteins exposing broadly neutralizing epitopes.
Autorzy:
Rosengarten JF; Research Group Pharmaceutical Biotechnology, Faculty of Applied Natural Sciences, TH Köln - University of Applied Sciences, Chempark Leverkusen E28, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany; Institute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167, Hannover, Germany.
Schatz S; Research Group Pharmaceutical Biotechnology, Faculty of Applied Natural Sciences, TH Köln - University of Applied Sciences, Chempark Leverkusen E28, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany; Institute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167, Hannover, Germany.
Wolf T; Research Group Process Engineering, Faculty of Applied Natural Sciences, TH Köln - University of Applied Sciences, Chempark Leverkusen E28, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany; Institute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167, Hannover, Germany.
Barbe S; Research Group Process Engineering, Faculty of Applied Natural Sciences, TH Köln - University of Applied Sciences, Chempark Leverkusen E28, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany.
Stitz J; Research Group Pharmaceutical Biotechnology, Faculty of Applied Natural Sciences, TH Köln - University of Applied Sciences, Chempark Leverkusen E28, Kaiser-Wilhelm-Allee, 51368, Leverkusen, Germany. Electronic address: .
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Źródło:
Virology [Virology] 2022 Mar; Vol. 568, pp. 41-48. Date of Electronic Publication: 2022 Jan 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
AIDS Vaccines/*immunology
Broadly Neutralizing Antibodies/*immunology
HIV Antibodies/*immunology
HIV Infections/*immunology
HIV-1/*immunology
Vaccines, Virus-Like Particle/*immunology
env Gene Products, Human Immunodeficiency Virus/*immunology
Antibody Specificity/immunology ; Epitopes/genetics ; Epitopes/immunology ; Gene Order ; Genetic Vectors/genetics ; HIV Infections/prevention & control ; Host-Pathogen Interactions ; Humans ; Vaccines, Virus-Like Particle/ultrastructure ; env Gene Products, Human Immunodeficiency Virus/genetics
Czasopismo naukowe
Tytuł:
Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice.
Autorzy:
Mangala Prasad V; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Leaman DP; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Lovendahl KN; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Croft JT; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Benhaim MA; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Hodge EA; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Zwick MB; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA; Biological Physics, Structure and Design Graduate Program, University of Washington, Seattle, WA 98195, USA; Department of Microbiology, University of Washington, Seattle, WA 98195, USA. Electronic address: .
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Źródło:
Cell [Cell] 2022 Feb 17; Vol. 185 (4), pp. 641-653.e17. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cryoelectron Microscopy*
Electron Microscope Tomography*
Virion/*ultrastructure
env Gene Products, Human Immunodeficiency Virus/*ultrastructure
gag Gene Products, Human Immunodeficiency Virus/*ultrastructure
2,2'-Dipyridyl/analogs & derivatives ; 2,2'-Dipyridyl/pharmacology ; Amino Acid Sequence ; Disulfides/pharmacology ; Epitopes/chemistry ; HEK293 Cells ; HIV Envelope Protein gp41/chemistry ; Humans ; Hydrogen Deuterium Exchange-Mass Spectrometry ; Models, Molecular ; Neutralization Tests ; Peptides/chemistry ; Polysaccharides/chemistry ; Protein Domains ; Protein Structure, Secondary ; Protein Subunits/chemistry ; env Gene Products, Human Immunodeficiency Virus/chemistry
Czasopismo naukowe
Tytuł:
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Autorzy:
Xu Z; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Walker S; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Wise MC; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Chokkalingam N; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Purwar M; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Moore A; Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
Tello-Ruiz E; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Wu Y; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Majumdar S; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Konrath KM; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Kulkarni A; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Tursi NJ; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Zaidi FI; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Reuschel EL; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Patel I; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Obeirne A; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Du J; Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
Schultheis K; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Gites L; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Smith T; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Mendoza J; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Broderick KE; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Humeau L; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Pallesen J; Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN, 47405, USA.
Weiner DB; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
Kulp DW; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA. .
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Źródło:
Nature communications [Nat Commun] 2022 Feb 04; Vol. 13 (1), pp. 695. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
AIDS Vaccines/*immunology
Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
HIV Infections/*immunology
HIV-1/*immunology
Vaccines, DNA/*immunology
env Gene Products, Human Immunodeficiency Virus/*immunology
AIDS Vaccines/administration & dosage ; Animals ; Antibodies, Neutralizing/ultrastructure ; Antigens, Viral/immunology ; Cell Line, Tumor ; Cryoelectron Microscopy ; Enzyme-Linked Immunospot Assay ; Epitopes/immunology ; HEK293 Cells ; HIV Antibodies/ultrastructure ; HIV Infections/prevention & control ; HIV Infections/virology ; HIV-1/physiology ; Humans ; Interferon-gamma/immunology ; Interferon-gamma/metabolism ; Mice, Inbred BALB C ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology ; Vaccination/methods ; Vaccines, DNA/administration & dosage ; env Gene Products, Human Immunodeficiency Virus/chemistry
Czasopismo naukowe
Tytuł:
The evolution of endogenous retroviral envelope genes in bats and their potential contribution to host biology.
Autorzy:
Skirmuntt EC; Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK.
Katzourakis A; Department of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK. Electronic address: .
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Źródło:
Virus research [Virus Res] 2019 Sep; Vol. 270, pp. 197645. Date of Electronic Publication: 2019 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Evolution, Molecular*
Genes, env*
Phylogeny*
Chiroptera/*virology
Endogenous Retroviruses/*genetics
Host Microbial Interactions/*genetics
Animals ; Gene Products, env/genetics ; Genome ; Pregnancy Proteins/genetics
Czasopismo naukowe
Tytuł:
A Protocol for Studying HIV-1 Envelope Glycoprotein Function.
Autorzy:
Ratnapriya S; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Chov A; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Herschhorn A; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.; Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, Minneapolis, MN 55455, USA.; The College of Veterinary Medicine Graduate Program, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło:
STAR protocols [STAR Protoc] 2020 Oct 14; Vol. 1 (3), pp. 100133. Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Evaluation, Preclinical/*methods
env Gene Products, Human Immunodeficiency Virus/*drug effects
env Gene Products, Human Immunodeficiency Virus/*isolation & purification
Antibodies, Neutralizing/immunology ; CD4 Antigens/metabolism ; Genes, env/genetics ; Glycoproteins/drug effects ; Glycoproteins/isolation & purification ; Glycoproteins/physiology ; HIV Antibodies/immunology ; HIV-1/genetics ; HIV-1/metabolism ; Humans ; Ligands ; Receptors, CCR5/metabolism ; Virus Internalization ; env Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
Tytuł:
HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals.
Autorzy:
Prévost J; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC H2X 0A9, Canada.
Medjahed H; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.
Vézina D; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.
Chen HC; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
Hahn BH; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6076, USA.
Smith AB 3rd; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
Finzi A; Centre de Recherche du CHUM, Montreal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC H2X 0A9, Canada.
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Źródło:
Viruses [Viruses] 2021 Nov 06; Vol. 13 (11). Date of Electronic Publication: 2021 Nov 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibody-Dependent Cell Cytotoxicity/*immunology
HIV Infections/*immunology
HIV-1/*immunology
env Gene Products, Human Immunodeficiency Virus/*metabolism
Amino Acid Motifs ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/virology ; Cell Membrane/metabolism ; HIV Antibodies/immunology ; HIV Envelope Protein gp160/chemistry ; HIV Envelope Protein gp160/genetics ; HIV Envelope Protein gp160/metabolism ; HIV-1/metabolism ; Humans ; Mutation ; Protein Conformation ; Proteolysis ; Virion/immunology ; Virion/metabolism ; env Gene Products, Human Immunodeficiency Virus/chemistry ; env Gene Products, Human Immunodeficiency Virus/genetics
Czasopismo naukowe
Tytuł:
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Autorzy:
Friedrich N; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Stiegeler E; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Roche Diagnostics GmbH, Nonnenwald 2, 82377, Penzberg, Deutschland.
Glögl M; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Lemmin T; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Department of Computer Science, ETH Zurich, Zurich, Switzerland.; Euler Institute, Faculty of Biomedicine, Università della Svizzera italiana (USI), Lugano, Switzerland.
Hansen S; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.; NGM Bio, 333 Oysterpoint Blvd, South San Francisco, CA, 94080, USA.
Kadelka C; Department of Mathematics, Iowa State University, Ames, IA, USA.
Wu Y; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.; Innovent Biologics Inc, 168 Dongping Street, Suzhou Industrial Park, 215123, China.
Ernst P; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.; Office Research and Teaching, Medical Faculty, University of Zurich, Zurich, Switzerland.
Maliqi L; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Foulkes C; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Morin M; Department of Chemistry, University of Zurich (UZH), Zurich, Switzerland.; BeiGene Switzerland GmbH, Aeschengraben 27, 4051, Basel, Switzerland.
Eroglu M; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Janssen Vaccines AG, Rehhagstrasse 79, 3018, Bern, Switzerland.
Liechti T; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
Ivan B; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Laboratory Medicine, Division of Clinical Chemistry, University Hospital Basel, Basel, Switzerland.
Reinberg T; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
Schaefer JV; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.; Novartis Institutes for BioMedical Research, Chemical Biology & Therapeutics (CBT), Novartis Pharma AG, Virchow 16, 4056, Basel, Switzerland.
Karakus U; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Ursprung S; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; University of Cambridge School of Clinical Medicine, Department of Radiology, Cambridge, CB2 0QQ, UK.
Mann A; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Roche Innovation Center Zurich, Roche Pharmaceutical Research and Early Development (pRED), Wagistrasse 10, 8952, Schlieren, Switzerland.
Rusert P; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.
Kouyos RD; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich (USZ), Zurich, Switzerland.
Robinson JA; Department of Chemistry, University of Zurich (UZH), Zurich, Switzerland.
Günthard HF; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland.; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich (USZ), Zurich, Switzerland.
Plückthun A; Department of Biochemistry, University of Zurich (UZH), Zurich, Switzerland.
Trkola A; Institute of Medical Virology, University of Zurich (UZH), Zurich, Switzerland. .
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Źródło:
Nature communications [Nat Commun] 2021 Nov 18; Vol. 12 (1), pp. 6705. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Conformation*
Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
HIV-1/*immunology
env Gene Products, Human Immunodeficiency Virus/*chemistry
Antibodies, Neutralizing/metabolism ; Cell Line, Tumor ; Epitopes/genetics ; Epitopes/immunology ; Epitopes/metabolism ; HEK293 Cells ; HIV Antibodies/metabolism ; HIV-1/genetics ; HIV-1/metabolism ; Humans ; Immunoglobulin G/immunology ; Immunoglobulin G/metabolism ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutation ; Protein Binding ; env Gene Products, Human Immunodeficiency Virus/genetics ; env Gene Products, Human Immunodeficiency Virus/immunology
Czasopismo naukowe
Tytuł:
Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies.
Autorzy:
Boutin M; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
Vézina D; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Ding S; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Prévost J; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
Laumaea A; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
Marchitto L; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
Anand SP; Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Medjahed H; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Gendron-Lepage G; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Bourassa C; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Goyette G; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.
Clark A; ViiV Healthcare, Global Medical Affairs, Middlesex, United Kingdom.
Richard J; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
Finzi A; Centre de Recherche du CHUM (CRCHUM), Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
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Źródło:
MBio [mBio] 2022 Jun 28; Vol. 13 (3), pp. e0057722. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-HIV Agents*
HIV Infections*/drug therapy
HIV Seropositivity*
HIV-1*
Antibodies, Neutralizing ; Broadly Neutralizing Antibodies ; Glycoproteins ; HIV Antibodies ; HIV Envelope Protein gp120 ; Humans ; Polysaccharides/metabolism ; env Gene Products, Human Immunodeficiency Virus
Czasopismo naukowe
Tytuł:
Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Autorzy:
Cottrell CA; IAVI Neutralizing Antibody Center, Consortium for HIV/AIDS Vaccine Development (CHAVD), Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Manne K; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Kong R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Wang S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Edwards RJ; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Henderson R; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Janowska K; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Kopp M; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Lin BC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Olia AS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Rawi R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Shen CH; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Taft JD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Torres JL; IAVI Neutralizing Antibody Center, Consortium for HIV/AIDS Vaccine Development (CHAVD), Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Wu NR; IAVI Neutralizing Antibody Center, Consortium for HIV/AIDS Vaccine Development (CHAVD), Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Zhang B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Cohen MS; Departments of Medicine, Epidemiology, and Microbiology, University of North Carolina-Chapel Hill, Chapel Hill, NC 27599, USA.
Haynes BF; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA.
Shapiro L; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
Ward AB; IAVI Neutralizing Antibody Center, Consortium for HIV/AIDS Vaccine Development (CHAVD), Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Acharya P; Duke University Human Vaccine Institute, Departments of Medicine and Surgery, Duke University School of Medicine, Durham, NC 27710, USA; Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC 27710, USA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: .
Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2021 Nov 02; Vol. 37 (5), pp. 109922.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Epitopes*
AIDS Vaccines/*immunology
Broadly Neutralizing Antibodies/*immunology
HIV-1/*immunology
Polysaccharides/*immunology
env Gene Products, Human Immunodeficiency Virus/*immunology
AIDS Vaccines/metabolism ; Antibody Specificity ; Binding Sites, Antibody ; Broadly Neutralizing Antibodies/metabolism ; Broadly Neutralizing Antibodies/ultrastructure ; CD4 Antigens/immunology ; CD4 Antigens/metabolism ; Cryoelectron Microscopy ; HEK293 Cells ; HIV-1/metabolism ; Humans ; Models, Molecular ; Polysaccharides/metabolism ; Protein Binding ; Protein Conformation ; Single Molecule Imaging ; Structure-Activity Relationship ; env Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
Tytuł:
Syncytins expressed in human placental trophoblast.
Autorzy:
Roberts RM; Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA. Electronic address: .
Ezashi T; Division of Animal Sciences, University of Missouri, Columbia, MO, 65211, USA; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Schulz LC; Department of Obstetrics and Gynecology, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Sugimoto J; Department of Obstetrics and Gynecology, Hiroshima University, Hiroshima, 7348551, Japan.
Schust DJ; Department of Obstetrics and Gynecology, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Khan T; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Zhou J; Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA; Department of Obstetrics and Gynecology, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
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Źródło:
Placenta [Placenta] 2021 Sep 15; Vol. 113, pp. 8-14. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Biological Evolution*
Placentation*
Endogenous Retroviruses/*genetics
Gene Products, env/*metabolism
Pregnancy Proteins/*metabolism
Trophoblasts/*metabolism
Cell Fusion ; Female ; Gene Products, env/genetics ; Humans ; Pregnancy ; Pregnancy Proteins/genetics
Czasopismo naukowe
Tytuł:
Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations.
Autorzy:
Swanson O; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Rhodes B; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Wang A; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Xia SM; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Parks R; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Chen H; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Sanzone A; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Cooper M; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA.
Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.
Lin BC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.
Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.
Bonsignori M; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA; Department of Medicine, Duke University, Durham, NC 27610, USA.
Saunders KO; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA; Department of Surgery, Duke University, Durham, NC 27610, USA.
Wiehe K; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA; Department of Medicine, Duke University, Durham, NC 27610, USA.
Haynes BF; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA; Department of Medicine, Duke University, Durham, NC 27610, USA; Department of Immunology, Duke University, Durham, NC 27610, USA.
Azoitei ML; Duke Human Vaccine Institute, Duke University, Durham, NC 27610, USA; Department of Medicine, Duke University, Durham, NC 27610, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2021 Aug 17; Vol. 36 (7), pp. 109561.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Lineage*
Antibodies, Neutralizing/*immunology
B-Lymphocytes/*cytology
Mutation/*genetics
env Gene Products, Human Immunodeficiency Virus/*genetics
env Gene Products, Human Immunodeficiency Virus/*immunology
Amino Acid Sequence ; Cell Line ; Humans ; Mutagenesis/genetics ; Protein Binding ; Vaccination ; env Gene Products, Human Immunodeficiency Virus/chemistry
Czasopismo naukowe
Tytuł:
Elicitation of Neutralizing Antibody Responses to HIV-1 Immunization with Nanoparticle Vaccine Platforms.
Autorzy:
Murji AA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Qin JS; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Hermanus T; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa.
Morris L; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2131, South Africa.; Antibody Immunity Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban 4041, South Africa.
Georgiev IS; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Program in Computational Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA.; Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37232, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
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Źródło:
Viruses [Viruses] 2021 Jul 02; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
AIDS Vaccines/*immunology
Antibodies, Neutralizing/*immunology
HIV Antibodies/*blood
HIV Infections/*prevention & control
HIV-1/*immunology
Nanoparticles/*administration & dosage
env Gene Products, Human Immunodeficiency Virus/*immunology
AIDS Vaccines/administration & dosage ; Animals ; Antibodies, Neutralizing/biosynthesis ; Female ; Guinea Pigs ; HIV Infections/immunology ; HIV-1/classification ; HIV-1/genetics ; Immunization ; Mice ; Mice, Inbred BALB C ; Nanoparticles/chemistry ; env Gene Products, Human Immunodeficiency Virus/classification ; env Gene Products, Human Immunodeficiency Virus/genetics
Czasopismo naukowe
Tytuł:
Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study.
Autorzy:
Perdiguero B; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Instituto de Salud Carlos III (CIBERINFEC, ISCIII ), Madrid, Spain.
Asbach B; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
Gómez CE; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Instituto de Salud Carlos III (CIBERINFEC, ISCIII ), Madrid, Spain.
Köstler J; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.
Barnett SW; Novartis Vaccines, Cambridge, MA, United States.
Koutsoukos M; Department of Product Development, GlaxoSmithKline (GSK) Vaccines, Rixensart, Belgium.
Weiss DE; Department of Immunobiology, Advanced BioScience Laboratories (ABL) Inc., Rockville, MD, United States.
Cristillo AD; Department of Immunobiology, Advanced BioScience Laboratories (ABL) Inc., Rockville, MD, United States.
Foulds KE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Montefiori DC; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Yates NL; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Ferrari G; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Shen X; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Sawant S; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Tomaras GD; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, NC, United States.
Sato A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
Fulp WJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
Gottardo R; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.; Biomedical Data Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.; Translational Data Science, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Ding S; EuroVacc Foundation EuroVacc Programme Coordinator, Lausanne, Switzerland.
Heeney JL; Lab of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Pantaleo G; Division of Immunology and Allergy, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.
Esteban M; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Instituto de Salud Carlos III (CIBERINFEC, ISCIII ), Madrid, Spain.
Wagner R; Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jul 22; Vol. 13, pp. 939627. Date of Electronic Publication: 2022 Jul 22 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
AIDS Vaccines*
HIV Infections*/prevention & control
HIV Seropositivity*
HIV-1*
Animals ; Antibodies, Neutralizing ; DNA ; Gene Products, env ; HIV Antibodies ; Macaca mulatta
Czasopismo naukowe
Tytuł:
Quantification of prefusion conformation for HIV vaccine using size-exclusion chromatography.
Autorzy:
Gollapudi D; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA.
Shadrick W; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA.
Yang Y; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA.
Gowetski DB; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA.
Gall J; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA.
Paula Lei Q; Vaccine Production Program, VRC, NIAID, NIH, 9 W. Watkins Mill Road, Gaithersburg, MD, USA. Electronic address: .
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Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2022 Jun 30; Vol. 1201-1202, pp. 123296. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
AIDS Vaccines*/chemistry
HIV-1*
Antibodies, Neutralizing ; Chromatography, Gel ; HIV Antibodies ; Protein Conformation ; env Gene Products, Human Immunodeficiency Virus/metabolism
Czasopismo naukowe
Tytuł:
B cells expressing IgM B cell receptors of HIV-1 neutralizing antibodies discriminate antigen affinities by sensing binding association rates.
Autorzy:
Hossain MA; Human Vaccine Institute, Duke University, Durham, NC, USA.
Anasti K; Human Vaccine Institute, Duke University, Durham, NC, USA.
Watts B; Human Vaccine Institute, Duke University, Durham, NC, USA.
Cronin K; Human Vaccine Institute, Duke University, Durham, NC, USA.
Derking R; Human Vaccine Institute, Duke University, Durham, NC, USA.
Groschel B; Department of Immunology & Microbiology and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.
Kane AP; Human Vaccine Institute, Duke University, Durham, NC, USA.
Edwards RJ; Human Vaccine Institute, Duke University, Durham, NC, USA.
Easterhoff D; Human Vaccine Institute, Duke University, Durham, NC, USA.
Zhang J; Applied Biomedical Science Institute, San Diego, CA, USA.
Rountree W; Human Vaccine Institute, Duke University, Durham, NC, USA.
Ortiz Y; Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany.
Saunders K; Human Vaccine Institute, Duke University, Durham, NC, USA.
Schief WR; Department of Immunology & Microbiology and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.
Sanders RW; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam Infection & Immunity Institute, Amsterdam, the Netherlands.
Verkoczy L; Applied Biomedical Science Institute, San Diego, CA, USA.
Reth M; Signaling Research Centers BIOSS and CIBSS, Freiburg, Germany; Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany.
Alam SM; Human Vaccine Institute, Duke University, Durham, NC, USA; Department of Medicine & Pathology, Duke University, Durham, NC, USA. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Jun 28; Vol. 39 (13), pp. 111021.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*
Antibodies, Neutralizing ; Antigens, Viral ; HIV Antibodies ; Immunoglobulin M ; Receptors, Antigen, B-Cell/metabolism ; env Gene Products, Human Immunodeficiency Virus
Czasopismo naukowe

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