Temat: "Enzyme Induction" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Label-free chemical imaging of cytochrome P450 activity by Raman microscopy.
Autorzy:: Li M; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Department of Applied Physics, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Nawa Y; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Department of Applied Physics, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Ishida S; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Division of Applied Life Science, Graduate School of Engineering, Sojo University, 4-22-1, Ikeda, Nishi-ku, Kumamoto, 860-0082, Japan.; Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, 210-9501, Japan.
Kanda Y; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.; Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, 210-9501, Japan.
Fujita S; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. .; Department of Applied Physics, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. .
Fujita K; AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. .; Department of Applied Physics, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. .; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2022 Aug 22; Vol. 5 (1), pp. 778. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytochrome P-450 Enzyme System*/genetics
Microscopy*
Enzyme Induction ; Hepatocytes/metabolism

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Skocz do pozycji: 2.

Tytuł:: Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization.
Autorzy:: Cantiello M; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Carletti M; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Giantin M; Department of Comparative Biomedicine and Food Science, University of Padua, 35020 Agripolis Legnaro, Italy.
Gardini G; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Capolongo F; Department of Comparative Biomedicine and Food Science, University of Padua, 35020 Agripolis Legnaro, Italy.
Cascio P; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Pauletto M; Department of Comparative Biomedicine and Food Science, University of Padua, 35020 Agripolis Legnaro, Italy.
Girolami F; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Dacasto M; Department of Comparative Biomedicine and Food Science, University of Padua, 35020 Agripolis Legnaro, Italy.
Nebbia C; Department of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 24; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 24.
Typ publikacji:: Journal Article
MeSH Terms:: Phenobarbital*/pharmacology
Xenobiotics*/metabolism
Animals ; Cattle ; Cytochrome P-450 Enzyme System/metabolism ; Enzyme Induction ; Liver/metabolism ; Microsomes, Liver/metabolism

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Skocz do pozycji: 3.

Tytuł:: Emerging Glycation-Based Therapeutics-Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors.
Autorzy:: Rabbani N; Department of Basic Medical Science, College of Medicine, Qatar University Health, Qatar University, Doha P.O. Box 2713, Qatar.
Thornalley PJ; Diabetes Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, Doha P.O. Box 34110, Qatar.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Feb 23; Vol. 23 (5). Date of Electronic Publication: 2022 Feb 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Diabetes Mellitus, Type 2/*drug therapy
Glutathione/*analogs & derivatives
Hesperidin/*therapeutic use
Lactoylglutathione Lyase/*metabolism
Neoplasms, Experimental/*drug therapy
Resveratrol/*therapeutic use
Animals ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/physiopathology ; Drug Therapy, Combination ; Enzyme Induction/drug effects ; Glutathione/chemistry ; Glutathione/therapeutic use ; Glycosylation/drug effects ; Hesperidin/chemistry ; Humans ; Insulin Resistance/physiology ; Lactoylglutathione Lyase/antagonists & inhibitors ; Mice ; Molecular Structure ; Neoplasms, Experimental/metabolism ; Obesity/drug therapy ; Obesity/metabolism ; Obesity/physiopathology ; Pyruvaldehyde/chemistry ; Pyruvaldehyde/metabolism ; Resveratrol/chemistry

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Skocz do pozycji: 4.

Tytuł:: Heme Oxygenase-1 Inhibits the Proliferation of Hepatic Stellate Cells by Activating PPAR γ and Suppressing NF- κ B.
Autorzy:: Yang H; Department of Infectious Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Zhang L; Department of Infectious Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Chen J; Department of Infectious Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Zhang X; Department of Infectious Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Zhao Z; Institute of Hepatopathy, Changzhi Medical College, Changzhi, Shanxi Province, China.
Zhao L; Department of Infectious Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.; Pokaż więcej
Źródło:: Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Jan 10; Vol. 2022, pp. 8920861. Date of Electronic Publication: 2022 Jan 10 (Print Publication: 2022).
Typ publikacji:: Journal Article; Retracted Publication
MeSH Terms:: Heme Oxygenase (Decyclizing)/*metabolism
Hepatic Stellate Cells/*cytology
Hepatic Stellate Cells/*metabolism
NF-kappa B/*metabolism
PPAR gamma/*metabolism
Actins/genetics ; Actins/metabolism ; Animals ; Biomarkers/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Computational Biology ; Enzyme Induction/drug effects ; Enzyme Inhibitors/pharmacology ; Heme Oxygenase (Decyclizing)/antagonists & inhibitors ; Heme Oxygenase (Decyclizing)/biosynthesis ; Hemin/pharmacology ; Hepatic Stellate Cells/drug effects ; Humans ; Liver Cirrhosis/etiology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Models, Biological ; NF-kappa B/antagonists & inhibitors ; PPAR gamma/agonists ; PPAR gamma/genetics ; Protoporphyrins/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats

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Skocz do pozycji: 5.

Tytuł:: Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma.
Autorzy:: Davis JL; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO, United States of America.
Thaler R; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States of America.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States of America.
Cox L; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO, United States of America.
Ricci B; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, United States of America.
Zannit HM; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, United States of America.
Wan F; Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO, United States of America.
Faccio R; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, United States of America.; Shriners Hospitals for Children-St. Louis, St. Louis, MO, United States of America.
Dudakovic A; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States of America.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States of America.
van Wijnen AJ; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States of America.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States of America.
Veis DJ; Musculoskeletal Research Center, Washington University School of Medicine, St. Louis, MO, United States of America.; Department of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, MO, United States of America.; Shriners Hospitals for Children-St. Louis, St. Louis, MO, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jul 22; Vol. 16 (7), pp. e0254426. Date of Electronic Publication: 2021 Jul 22 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Integrases*/genetics
Integrases*/metabolism
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Protein Serine-Threonine Kinases*/biosynthesis
Protein Serine-Threonine Kinases*/genetics
S100 Calcium-Binding Protein A4*/genetics
S100 Calcium-Binding Protein A4*/metabolism
Sarcoma, Experimental*/genetics
Sarcoma, Experimental*/metabolism
Sarcoma, Experimental*/pathology
Sp7 Transcription Factor*/genetics
Sp7 Transcription Factor*/metabolism
Animals ; Enzyme Induction ; Mice ; Mice, Transgenic ; NF-kappaB-Inducing Kinase

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Skocz do pozycji: 6.

Tytuł:: A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction.
Autorzy:: Li H; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Wang YG; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.
Ma ZC; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.
Yun-Hang G; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ling S; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Teng-Fei C; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Guang-Ping Z; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Gao Y; Institute of Radiation Medicine Academy of Military Medical Sciences, Beijing, China.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jul; Vol. 51 (7), pp. 752-763. Date of Electronic Publication: 2021 May 03.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 CYP3A*/metabolism
Receptors, Steroid*/genetics
Receptors, Steroid*/metabolism
Cytochrome P-450 CYP1A1 ; Cytochrome P-450 CYP2B6/genetics ; Cytochrome P-450 CYP2B6/metabolism ; Enzyme Induction ; Genes, Reporter ; Hepatocytes/metabolism ; Luciferases/genetics

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Skocz do pozycji: 7.

Tytuł:: Exogenous Vitamins K Exert Anti-Inflammatory Effects Dissociated from Their Role as Substrates for Synthesis of Endogenous MK-4 in Murine Macrophages Cell Line.
Autorzy:: Kieronska-Rudek A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.; Department of Pharmacology, Medical College, Jagiellonian University, Grzegorzecka 16, 31-531 Krakow, Poland.
Kij A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Kaczara P; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Tworzydlo A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.
Napiorkowski M; Chemistry Department, Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warszawa, Poland.
Sidoryk K; Chemistry Department, Pharmaceutical Research Institute, Rydygiera 8, 01-793 Warszawa, Poland.
Chlopicki S; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348 Krakow, Poland.; Department of Pharmacology, Medical College, Jagiellonian University, Grzegorzecka 16, 31-531 Krakow, Poland.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Jun 22; Vol. 10 (7). Date of Electronic Publication: 2021 Jun 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Macrophages/*metabolism
Vitamin K/*pharmacology
Animals ; Atorvastatin/pharmacology ; Cell Respiration/drug effects ; Cyclooxygenase 2/biosynthesis ; Cytokines/biosynthesis ; Eicosanoids/biosynthesis ; Enzyme Induction/drug effects ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Mice ; Mitochondria/drug effects ; Mitochondria/metabolism ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase Type II/metabolism ; RAW 264.7 Cells ; Substrate Specificity/drug effects

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Skocz do pozycji: 8.

Tytuł:: Reduction of Superoxide Dismutase 1 Delays Regeneration of Cardiotoxin-Injured Skeletal Muscle in KK/Ta- Ins2 Mice with Progressive Diabetic Nephropathy.
Autorzy:: Takahashi Y; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Shimizu T; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Kato S; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Nara M; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Suganuma Y; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Sato T; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Morii T; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Yamada Y; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.; Kansai Electric Power Medical Research Institute, 2-1-7 Fukushima-ku, Osaka 553-0003, Japan.
Fujita H; Department of Metabolism and Endocrinology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 23; Vol. 22 (11). Date of Electronic Publication: 2021 May 23.
Typ publikacji:: Journal Article
MeSH Terms:: Diabetic Nephropathies/*complications
Muscle, Skeletal/*drug effects
Nerve Regeneration/*drug effects
Sarcopenia/*etiology
Superoxide Dismutase-1/*drug effects
Animals ; Cardiotoxins/toxicity ; Collagen Type I/biosynthesis ; Collagen Type I/genetics ; Collagen Type I, alpha 1 Chain ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/genetics ; Diabetic Nephropathies/enzymology ; Diabetic Nephropathies/genetics ; Diabetic Nephropathies/pathology ; Disease Progression ; Enzyme Induction/drug effects ; Fibrosis ; Gene Expression Regulation, Enzymologic ; Genetic Predisposition to Disease ; Glomerular Mesangium/pathology ; Inflammation ; Insulin/deficiency ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Muscle, Skeletal/enzymology ; Muscle, Skeletal/pathology ; Muscle, Skeletal/physiology ; Oxidative Stress/drug effects ; Superoxide Dismutase-1/biosynthesis ; Superoxide Dismutase-1/genetics ; Superoxide Dismutase-1/physiology ; Superoxides/metabolism

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Skocz do pozycji: 9.

Tytuł:: Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters.
Autorzy:: Ciscato F; Dipartimento di Scienze Biomediche, Università di Padova, 35131 Padova, Italy.
Ferrone L; Dipartimento di Scienze Biomediche, Università di Padova, 35131 Padova, Italy.
Masgras I; Dipartimento di Scienze Biomediche, Università di Padova, 35131 Padova, Italy.; Institute of Neuroscience, National Research Council, 56124 Pias, Italy.
Laquatra C; Dipartimento di Scienze Biomediche, Università di Padova, 35131 Padova, Italy.
Rasola A; Dipartimento di Scienze Biomediche, Università di Padova, 35131 Padova, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 29; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Hexokinase/*physiology
Neoplasm Proteins/*physiology
Neoplasms/*enzymology
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis/physiology ; Autophagy/physiology ; Calcium Signaling/physiology ; Cell Hypoxia ; Cell-Penetrating Peptides/therapeutic use ; Enzyme Induction ; Gene Expression Regulation, Neoplastic ; Glycolysis/physiology ; Hexokinase/antagonists & inhibitors ; Humans ; Intracellular Membranes/enzymology ; Mice ; MicroRNAs/genetics ; Mitochondria/metabolism ; Molecular Targeted Therapy ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasms/therapy ; Neoplasms, Experimental/enzymology ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Protein Processing, Post-Translational ; Rats ; Ubiquitination

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Skocz do pozycji: 10.

Tytuł:: Phosphofructokinases A and B from Mycobacterium tuberculosis Display Different Catalytic Properties and Allosteric Regulation.
Autorzy:: Snášel J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.
Machová I; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.
Šolínová V; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.
Kašička V; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.
Krečmerová M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.
Pichová I; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610 Prague 6, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 02; Vol. 22 (3). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Bacterial Proteins/*metabolism
Mycobacterium tuberculosis/*enzymology
Phosphofructokinases/*metabolism
Adenosine Diphosphate/metabolism ; Adenosine Diphosphate/pharmacology ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/pharmacology ; Allosteric Regulation ; Bacterial Proteins/antagonists & inhibitors ; Catalysis ; Enzyme Induction ; Feedback, Physiological ; Fructosediphosphates/biosynthesis ; Fructosediphosphates/pharmacology ; Fructosephosphates/metabolism ; Fructosephosphates/pharmacology ; Gluconeogenesis ; Glycolysis ; Hexosephosphates/metabolism ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Kinetics ; L-Lactate Dehydrogenase/metabolism ; Mycobacterium tuberculosis/drug effects ; Oxygen/pharmacology ; Phosphofructokinases/antagonists & inhibitors ; Pyruvate Kinase/metabolism ; Recombinant Proteins/metabolism ; Substrate Specificity

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Skocz do pozycji: 11.

Tytuł:: Involvement of heme oxygenase-1 in suppression of T cell activation by quercetin.
Autorzy:: Sugiyama T; Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Matsushima M; Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ohdachi T; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hashimoto N; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hasegawa Y; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yokoi K; Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kawabe T; Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2020 Aug; Vol. 42 (4), pp. 295-305. Date of Electronic Publication: 2020 May 12.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants/*pharmacology
Heme Oxygenase-1/*biosynthesis
Quercetin/*pharmacology
T-Lymphocytes/*drug effects
T-Lymphocytes/*enzymology
Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Cells, Cultured ; Dose-Response Relationship, Drug ; Enzyme Induction/drug effects ; Enzyme Induction/physiology ; Mice ; Mice, Inbred C57BL

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Skocz do pozycji: 12.

Tytuł:: Induction of defense-related enzymes and enhanced disease resistance in maize against Fusarium verticillioides by seed treatment with Jacaranda mimosifolia formulations.
Autorzy:: Naz R; Department of Biosciences, COMSATS University, Park Road, Chak Shahzad, Islamabad, Pakistan. .
Bano A; Department of Biosciences, University of Wah, Wah Cantt, Pakistan.
Nosheen A; Department of Biosciences, COMSATS University, Park Road, Chak Shahzad, Islamabad, Pakistan.
Yasmin H; Department of Biosciences, COMSATS University, Park Road, Chak Shahzad, Islamabad, Pakistan.
Keyani R; Department of Biosciences, COMSATS University, Park Road, Chak Shahzad, Islamabad, Pakistan.
Shah STA; Department of Biosciences, COMSATS University, Park Road, Chak Shahzad, Islamabad, Pakistan.
Anwar Z; Department of Computer Science, COMSATS University Islamabad, Vehari Campus, Islamabad, Pakistan.
Roberts TH; Plant Breeding Institute, Sydney Institute of Agriculture, University of Sydney, Sydney, NSW, 2006, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 08; Vol. 11 (1), pp. 59. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bignoniaceae*/chemistry
Fusarium*
Disease Resistance/*drug effects
Plant Diseases/*prevention & control
Plant Extracts/*therapeutic use
Seeds/*drug effects
Zea mays/*microbiology
Catechol Oxidase/metabolism ; Chitinases/metabolism ; Electrophoresis, Polyacrylamide Gel ; Enzyme Induction/drug effects ; Peptide Hydrolases/metabolism ; Peroxidase/metabolism ; Plant Diseases/microbiology ; Plant Leaves/chemistry ; Seeds/microbiology ; Zea mays/drug effects ; Zea mays/enzymology
SCR Organism:: Fusarium verticillioides

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Skocz do pozycji: 13.

Tytuł:: The Role of the Renin-Angiotensin System in Severe Acute Respiratory Syndrome-CoV-2 Infection.
Autorzy:: Alfano G; Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy, .; Clinic of Infectious Diseases, University Hospital of Modena, Modena, Italy, .
Guaraldi G; Department of Nephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Fontana F; Clinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Ferrari A; Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
Magistroni R; Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.; Clinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Mussini C; Department of Nephrology Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Cappelli G; Surgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.; Clinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.; Pokaż więcej
Corporate Authors:: Modena Covid-19 Working Group (MoCo19)
Źródło:: Blood purification [Blood Purif] 2021; Vol. 50 (2), pp. 263-267. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji:: Letter
MeSH Terms:: COVID-19/*complications
Renin-Angiotensin System/*physiology
Respiratory Distress Syndrome/*etiology
SARS-CoV-2/*physiology
Adult ; Angiotensin I/physiology ; Angiotensin II/physiology ; Angiotensin Receptor Antagonists/pharmacology ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme 2/physiology ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Animals ; Antihypertensive Agents/therapeutic use ; Down-Regulation ; Enzyme Induction ; Female ; Host-Pathogen Interactions ; Humans ; Hypertension/drug therapy ; Lung/enzymology ; Lung/physiopathology ; Lung/virology ; Male ; Organ Specificity ; Receptors, Coronavirus/physiology ; Respiratory Distress Syndrome/physiopathology ; Virus Internalization

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Skocz do pozycji: 14.

Tytuł:: Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells.
Autorzy:: Goedtke L; Department Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589 Berlin, Germany.
Sprenger H; Department Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589 Berlin, Germany.
Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, and University of Tübingen, 72074 Tübingen, Germany.
Schmidt FF; SIGNATOPE GmbH, Markwiesenstraße 55, 72770 Reutlingen, Germany.
Hammer HS; SIGNATOPE GmbH, Markwiesenstraße 55, 72770 Reutlingen, Germany.
Zanger UM; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, and University of Tübingen, 72074 Tübingen, Germany.
Poetz O; SIGNATOPE GmbH, Markwiesenstraße 55, 72770 Reutlingen, Germany.
Seidel A; Biochemical Institute for Environmental Carcinogens, Prof. Dr. Gernot Grimmer Foundation, Lurup 4, 22927 Grosshansdorf, Germany.
Braeuning A; Department Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589 Berlin, Germany.
Hessel-Pras S; Department Food Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589 Berlin, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 31; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 31.
Typ publikacji:: Journal Article
MeSH Terms:: Basic Helix-Loop-Helix Transcription Factors/*metabolism
Carcinoma, Hepatocellular/*metabolism
Gene Expression Regulation, Neoplastic/*drug effects
Liver Neoplasms/*metabolism
Polycyclic Aromatic Hydrocarbons/*pharmacology
Receptors, Aryl Hydrocarbon/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Xenobiotics/*metabolism
Basic Helix-Loop-Helix Transcription Factors/genetics ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Constitutive Androstane Receptor ; Cytochrome P-450 Enzyme System/metabolism ; Enzyme Induction ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Transcriptional Activation

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Skocz do pozycji: 15.

Tytuł:: Visfatin Triggers the Cell Motility of Non-Small Cell Lung Cancer via Up-Regulation of Matrix Metalloproteinases.
Autorzy:: Wang G; Department of Respiratory Medicine, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China.
Tian W; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Liu Y; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Ju Y; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Shen Y; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Zhao S; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Zhang B; Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Li Y; Department of Respiratory Medicine, Qilu Hospital, Shandong University, Jinan, Shandong, China.; Pokaż więcej
Źródło:: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2016 Dec; Vol. 119 (6), pp. 548-554. Date of Electronic Publication: 2016 Jul 21.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Induction*
Up-Regulation*
Carcinoma, Non-Small-Cell Lung/*blood
Cytokines/*blood
Lung Neoplasms/*blood
Matrix Metalloproteinase 2/*metabolism
Matrix Metalloproteinase 9/*metabolism
Nicotinamide Phosphoribosyltransferase/*blood
Aged ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Non-Small-Cell Lung/secondary ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cytokines/metabolism ; Female ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Lymphatic Metastasis ; Male ; Matrix Metalloproteinase 2/chemistry ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 9/chemistry ; Matrix Metalloproteinase 9/genetics ; Middle Aged ; NF-KappaB Inhibitor alpha/metabolism ; Neoplasm Invasiveness ; Neoplasm Staging ; Nicotinamide Phosphoribosyltransferase/metabolism ; Phosphorylation ; Protein Processing, Post-Translational ; RNA Interference

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Skocz do pozycji: 16.

Tytuł:: Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations.
Autorzy:: Donocoff RS; Institute of Comparative Medicine, Columbia University Medical Center, Columbia University, New York, NY, 10032, USA.
Teteloshvili N; Department of Medicine, Columbia Center for Translational Immunology and Naomi Berrie Diabetes Center, Columbia University, New York, NY, 10032, USA.
Chung H; Department of Medicine, Columbia Center for Translational Immunology and Naomi Berrie Diabetes Center, Columbia University, New York, NY, 10032, USA.
Shoulson R; Institute of Comparative Medicine, Columbia University Medical Center, Columbia University, New York, NY, 10032, USA.
Creusot RJ; Department of Medicine, Columbia Center for Translational Immunology and Naomi Berrie Diabetes Center, Columbia University, New York, NY, 10032, USA. .; Columbia Center for Translational Immunology, Columbia University Medical Center, 650 W. 168th Street, New York, NY, 10032, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Sep 17; Vol. 10 (1), pp. 15244. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Immune System/*cytology
Immune System/*enzymology
Integrases/*biosynthesis
Tamoxifen/*pharmacology
Administration, Oral ; Animals ; Bacterial Proteins/biosynthesis ; Bacterial Proteins/genetics ; Dose-Response Relationship, Drug ; Enzyme Induction/drug effects ; Female ; Genes, Reporter ; Immune System/drug effects ; Injections, Intraperitoneal ; Integrases/genetics ; Leukocyte Common Antigens/metabolism ; Liver/cytology ; Liver/drug effects ; Liver/immunology ; Luminescent Proteins/biosynthesis ; Luminescent Proteins/genetics ; Lymphoid Tissue/cytology ; Lymphoid Tissue/drug effects ; Lymphoid Tissue/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Spleen/cytology ; Spleen/drug effects ; Spleen/immunology ; Tamoxifen/administration & dosage ; Tamoxifen/pharmacokinetics

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Skocz do pozycji: 17.

Tytuł:: Diclofenac Degradation-Enzymes, Genetic Background and Cellular Alterations Triggered in Diclofenac-Metabolizing Strain Pseudomonas moorei KB4.
Autorzy:: Żur J; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland.
Piński A; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland.
Wojcieszyńska D; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland.
Smułek W; Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo 4, 60-695 Poznan, Poland.
Guzik U; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 16; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents, Non-Steroidal/*metabolism
Bacterial Proteins/*metabolism
Diclofenac/*metabolism
Pseudomonas/*metabolism
Water Pollutants, Chemical/*metabolism
Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Bacterial Proteins/genetics ; Biodegradation, Environmental ; Biotransformation/genetics ; Catalase/genetics ; Catalase/metabolism ; Cell Membrane Permeability/drug effects ; Culture Media/pharmacology ; Diclofenac/pharmacology ; Dioxygenases/genetics ; Dioxygenases/metabolism ; Enzyme Induction/drug effects ; Fatty Acids/metabolism ; Gene Expression Regulation, Bacterial/drug effects ; Glucose/pharmacology ; Lipid Peroxidation/drug effects ; Membrane Lipids/metabolism ; Membrane Potentials/drug effects ; Oxidative Stress/drug effects ; Pseudomonas/drug effects ; Sodium Acetate/pharmacology ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Water Pollutants, Chemical/pharmacology
SCR Organism:: Pseudomonas moorei

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Skocz do pozycji: 18.

Tytuł:: Cannabidiol Modifies the Formation of NETs in Neutrophils of Psoriatic Patients.
Autorzy:: Wójcik P; Department of Analytical Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.
Garley M; Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, 15-269 Bialystok, Poland.
Wroński A; Dermatological Specialized Center 'DERMAL' NZOZ in Bialystok, 15-453 Bialystok, Poland.
Jabłońska E; Department of Immunology, Medical University of Bialystok, Waszyngtona 15A, 15-269 Bialystok, Poland.
Skrzydlewska E; Department of Analytical Chemistry, Medical University of Bialystok, Mickiewicza 2D, 15-222 Bialystok, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 16; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: Cannabidiol/*pharmacology
Extracellular Traps/*drug effects
Neutrophils/*drug effects
Psoriasis/*immunology
Adult ; Case-Control Studies ; Cell-Free Nucleic Acids/analysis ; Culture Media, Conditioned/chemistry ; Drug Synergism ; Enzyme Induction/drug effects ; Female ; Humans ; Lipopolysaccharides/pharmacology ; Male ; NADPH Oxidases/biosynthesis ; NADPH Oxidases/physiology ; Oxidation-Reduction ; Peroxidase/analysis ; Psoriasis/blood ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 19.

Tytuł:: Salicylate-Induced Chitinases in Pea Roots.
Autorzy:: Egorova AM; Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, FRC, Kazan, Russia. .
Wielsch N; Max Planck Institute for Chemical Ecology, Jena, Germany.
Tarchevsky IA; Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, FRC, Kazan, Russia.; Pokaż więcej
Źródło:: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2020 Sep; Vol. 494 (1), pp. 240-243. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji:: Journal Article
MeSH Terms:: Chitinases/*biosynthesis
Gene Expression Regulation, Enzymologic/*drug effects
Pisum sativum/*drug effects
Pisum sativum/*enzymology
Salicylic Acid/*pharmacology
Anti-Infective Agents/pharmacology ; Chitinases/genetics ; Chitinases/metabolism ; Electrophoresis, Gel, Two-Dimensional/methods ; Enzyme Induction/drug effects ; Pisum sativum/genetics ; Plant Roots/drug effects ; Plant Roots/enzymology ; Plant Roots/genetics ; Proteomics/methods

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Skocz do pozycji: 20.

Tytuł:: Activation-induced cytidine deaminase overexpression in double-hit lymphoma: potential target for novel anticancer therapy.
Autorzy:: Zhang J; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, Zhejian, People's Republic of China.; Department of Hematology, Jinhua Hospital of Zhejiang University (Jinhua Municipal Central Hospital), Jinhua, 321100, Zhejiang, People's Republic of China.
Shi Y; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Zhao M; Department of Hematology, Jinhua Hospital of Zhejiang University (Jinhua Municipal Central Hospital), Jinhua, 321100, Zhejiang, People's Republic of China.
Hu H; Department of Hematology, Jinhua Hospital of Zhejiang University (Jinhua Municipal Central Hospital), Jinhua, 321100, Zhejiang, People's Republic of China. .
Huang H; Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, Zhejian, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Aug 25; Vol. 10 (1), pp. 14164. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Molecular Targeted Therapy*
Cytidine Deaminase/*biosynthesis
Immunoglobulin Class Switching/*genetics
Lymphoma, Large B-Cell, Diffuse/*enzymology
Neoplasm Proteins/*biosynthesis
Adult ; Aged ; Aged, 80 and over ; Cytidine Deaminase/genetics ; Cytidine Deaminase/physiology ; Enzyme Induction/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Genes, bcl-2 ; Genes, myc ; Humans ; Immunoglobulin Isotypes/biosynthesis ; Immunoglobulin Isotypes/blood ; Immunoglobulin Isotypes/genetics ; Kaplan-Meier Estimate ; Ki-67 Antigen/genetics ; Lipopolysaccharides/pharmacology ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/mortality ; Male ; Middle Aged ; Neoplasm Proteins/genetics ; Neoplasm Proteins/physiology ; Prognosis ; Proto-Oncogene Proteins c-bcl-6/genetics ; Translocation, Genetic ; Up-Regulation/drug effects

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