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Wyszukujesz frazę ""Enzyme Inhibitors/administration & dosage"" wg kryterium: Temat


Tytuł :
Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study
Autorzy :
Santema, Bernadet T.
Ouwerkerk, Wouter
Tromp, Jasper
Sama, Iziah E.
Ravera, Alice
Regitz-Zagrosek, Vera
Hillege, Hans
Samani, Nilesh J.
Zannad, Faiez
Dickstein, Kenneth
Lang, Chim C.
Cleland, John G.
Ter Maaten, Jozine M.
Metra, Marco
Anker, Stefan D.
van der Harst, Pim
Ng, Leong L.
van der Meer, Peter
van Veldhuisen, Dirk J.
Meyer, Sven
Lam, Carolyn S.P.
Voors, Adriaan A.
Richards, Arthur Mark
Anand, Inder
Hung, Chung-Lieh
Ling, Lieng Hsi
Liew, Houng Bang
Narasimhan, Calambur
Ngarmukos, Tachapong
Park, Sang Weon
Reyes, Eugenio
Siswanto, Bambang Budi
Shimizu, Wataru
Zhang, Shu
Pokaż więcej
Temat :
R1
Adrenergic beta-Antagonists/administration & dosage
Aged
Angiotensin Receptor Antagonists/administration & dosage
Angiotensin-Converting Enzyme Inhibitors/administration & dosage
Female
Heart Failure/drug therapy
Humans
Male
Prospective Studies
Sex Factors
Stroke Volume/drug effects
General Medicine
Prospective cohort study
Beta blocker
medicine.drug_class
medicine
Internal medicine
medicine.medical_specialty
Cohort study
business.industry
business
Observational study
Cohort
Heart failure
medicine.disease
Ejection fraction
ACE inhibitor
medicine.drug
Adrenergic beta-Antagonists
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Heart Failure
Stroke Volume
Źródło :
The Lancet, 394(10205), 1254-1263. ELSEVIER SCIENCE INC
Lancet, 394(10205), 1254-1263. Elsevier Limited
Crossref
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366985a7fad25da2f4f70f33a48d7e8b
http://eprints.gla.ac.uk/193969/7/193969.pdf
Tytuł :
Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)
Autorzy :
Ulrik M. Mogensen
Jean L. Rouleau
Akshay S. Desai
Pardeep S. Jhund
Li Shen
Milton Packer
Guenther Mueller-Velten
Martin Lefkowitz
Jianjian Gong
John J.V. McMurray
Michael R. Zile
Brian Claggett
Scott D. Solomon
Lars Køber
Karl Swedberg
Pokaż więcej
Temat :
Cardiology and Cardiovascular Medicine
Sacubitril
medicine.drug
medicine
Hazard ratio
Sacubitril, Valsartan
Internal medicine
medicine.medical_specialty
Clinical endpoint
Cardiology
Confidence interval
business.industry
business
Enalapril
Valsartan
Rate ratio
Aged
Aminobutyrates/administration & dosage
Angiotensin Receptor Antagonists/administration & dosage
Angiotensin-Converting Enzyme Inhibitors/administration & dosage
Dose-Response Relationship, Drug
Enalapril/administration & dosage
Europe/epidemiology
Female
Heart Failure/drug therapy
Humans
Male
Middle Aged
Morbidity/trends
Prospective Studies
Recurrence
Stroke Volume/physiology
Survival Rate/trends
Tetrazoles/administration & dosage
United States/epidemiology
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Heart failure
Hospitalization
Recurrent events
Neprilysin inhibitor
Research Article
Focus on Prognostic Variables
Medical Therapy
Źródło :
Crossref
Mogensen, U M, Gong, J, Jhund, P S, Shen, L, Køber, L, Desai, A S, Lefkowitz, M P, Packer, M, Rouleau, J L, Solomon, S D, Claggett, B L, Swedberg, K, Zile, M R, Mueller-Velten, G & McMurray, J J V 2018, ' Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF) ', European Journal of Heart Failure, vol. 20, no. 4, pp. 760-768 . https://doi.org/10.1002/ejhf.1139
European Journal of Heart Failure
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41227a4dca400eeb981bb61cd2758c28
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fejhf.1139
Tytuł :
Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression
Autorzy :
Sâmia R.L. Joca
Caroline Biojone
L.A. Stanquini
Francisco Silveira Guimarães
Pokaż więcej
Temat :
Biological Psychiatry
Psychiatry and Mental health
Behavioural despair test
Internal medicine
medicine.medical_specialty
medicine
Habituation
Antidepressant
Imipramine
medicine.drug
Nitric oxide synthase
biology.protein
biology
business.industry
business
Nitric oxide
chemistry.chemical_compound
chemistry
7-Nitroindazole
Endocrinology
Learned helplessness
Animals
Antidepressive Agents, Tricyclic/administration & dosage
Behavior, Animal/drug effects
Brain-Derived Neurotrophic Factor/drug effects
Depression/drug therapy
Disease Models, Animal
Enzyme Inhibitors/administration & dosage
Helplessness, Learned
Hippocampus/drug effects
Imipramine/pharmacology
Indazoles/pharmacology
Nitric Oxide Synthase/antagonists & inhibitors
Rats
Źródło :
Crossref
Stanquini, L A, Biojone, C, Guimarães, F S & Joca, S R 2018, ' Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression ' Acta Neuropsychiatrica, vol. 30, no. 3, pp. 127-136 . https://doi.org/10.1017/neu.2017.28
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bbf826880a6ebc2ee5d73b8fd4ba5d
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S092427081700028X
Tytuł :
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
Autorzy :
Manara, Maria Cristina
Valente, Sergio
Cristalli, Camilla
Nicoletti, Giordano
Landuzzi, Lorena
Zwergel, Clemens
Mazzone, Roberta
Stazi, Giulia
Arimondo, Paola B.
Pasello, Michela
Guerzoni, Clara
Picci, Piero
Nanni, Patrizia
Lollini, Pier-Luigi
Mai, Antonello
Scotlandi, Katia
Pokaż więcej
Temat :
MESH: Aminoquinolines/administration & dosage
MESH: Aminoquinolines/pharmacology
MESH: Cisplatin/administration & dosage
MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors
MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics
MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism
MESH: Doxorubicin/administration & dosage
MESH: Enzyme Inhibitors/administration & dosage
MESH: Enzyme Inhibitors/chemistry
MESH: Enzyme Inhibitors/pharmacology
MESH: Gene Expression Regulation, Neoplastic/drug effects
MESH: Humans
MESH: Animals
MESH: Male
MESH: Mice, Knockout
MESH: Osteosarcoma/drug therapy
MESH: Osteosarcoma/genetics
MESH: Osteosarcoma/metabolism
MESH: Quinolines/chemistry
MESH: Tumor Burden/drug effects
MESH: Tumor Burden/genetics
MESH: Xenograft Model Antitumor Assays
MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MESH: Benzamides/administration & dosage
MESH: Benzamides/pharmacology
MESH: Bone Neoplasms/drug therapy
MESH: Bone Neoplasms/genetics
MESH: Bone Neoplasms/metabolism
MESH: Cell Line, Tumor
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.CAN]Life Sciences [q-bio]/Cancer
Cancer Research
Oncology
Cancer research
Cellular differentiation
Chemistry
DNA damage
Cisplatin
medicine.drug
medicine
DNA methylation
Osteosarcoma
medicine.disease
DNA Methyltransferase Inhibitor
Doxorubicin
Nucleoside inhibitor
osteosarcoma
patient-derived xenograft (PDX)
chemotherapy
epigenetics
Źródło :
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Crossref
Opis pliku :
STAMPA
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55d5482d55dc2ed43ad6818ec4cbf60
https://hal.archives-ouvertes.fr/hal-02383680
Tytuł :
Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema
Autorzy :
Aygören-Pürsün, Emel
Bygum, Anette
Grivcheva-Panovska, Vesna
Magerl, Markus
Graff, Jochen
Steiner, Urs
Fain, Olivier
Huissoon, Aarnoud
Kinaciyan, Tamar
Farkas, Henriette
Lleonart, Ramon
Longhurst, Hilary
Rae, William
Triggiani, Massimo
Aberer, Werner
Cancian, Mauro
Zanichelli, Andrea
Smith, William
Baeza, Maria
Du-Thanh, Aurélie
Gompels, Mark
Gonzalez-Quevedo, Teresa
Greve, Jens
Guilarte, Mar
Katelaris, Constance
Dobo, Sylvia
Cornpropst, Melanie
Clemons, Desiree
Fang, Lei
Collis, Phil
Sheridan, William
Maurer, Marcus
Cicardi, Marco
Pokaż więcej
Temat :
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Administration, Oral
Adult
Aged
Angioedemas, Hereditary/prevention & control
Dose-Response Relationship, Drug
Double-Blind Method
Drug Administration Schedule
Enzyme Inhibitors/administration & dosage
Female
Humans
Male
Middle Aged
Plasma Kallikrein/antagonists & inhibitors
Quality of Life
General Medicine
Pharmacology
C1-inhibitor
biology.protein
biology
C1 esterase
Medicine
business.industry
business
Hereditary angioedema
medicine.disease
Plasma kallikrein inhibitor
Kallikrein
Angioedemas, Hereditary
Enzyme Inhibitors
Plasma Kallikrein
Settore MED/09 - Medicina Interna
Źródło :
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2018, 379 (4), pp.352-362. ⟨10.1056/NEJMoa1716995⟩
Aygören-Pürsün, E, Bygum, A, Grivcheva-Panovska, V, Magerl, M, Graff, J, Steiner, U C, Fain, O, Huissoon, A, Kinaciyan, T, Farkas, H, Lleonart, R, Longhurst, H J, Rae, W, Triggiani, M, Aberer, W, Cancian, M, Zanichelli, A, Smith, W B, Baeza, M L, Du-Thanh, A, Gompels, M, Gonzalez-Quevedo, T, Greve, J, Guilarte, M, Katelaris, C, Dobo, S, Cornpropst, M, Clemons, D, Fang, L, Collis, P, Sheridan, W, Maurer, M & Cicardi, M 2018, ' Oral plasma kallikrein inhibitor for prophylaxis in hereditary angioedema ', New England Journal of Medicine, vol. 379, no. 4, pp. 352-362 . https://doi.org/10.1056/NEJMoa1716995
Crossref
Fraunhofer IME
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ed3de98f37ce423e325ff7e1931c9d
https://hal.umontpellier.fr/hal-02318184
Tytuł :
Effect of ACE-inhibition on coronary microvascular function and symptoms in normotensive women with microvascular angina: A randomized placebo-controlled trial
Autorzy :
Michelsen, Marie Mide
Rask, Anna Bay
Suhrs, Elena
Raft, Kristoffer Flintholm
Høst, Nis
Prescott, Eva
Pokaż więcej
Temat :
lcsh:Medicine
lcsh:R
lcsh:Science
lcsh:Q
Multidisciplinary
Placebo-controlled study
Heart rate
Medicine
business.industry
business
Internal medicine
medicine.medical_specialty
Randomized controlled trial
law.invention
law
Cardiology
Ramipril
medicine.drug
Placebo
ACE inhibitor
Angina
medicine.disease
Blood pressure
Research Article
Medicine and Health Sciences
Vascular Medicine
Blood Pressure
Pharmacology
Drugs
ACE inhibitors
Biology and life sciences
Biochemistry
Enzymology
Enzyme inhibitors
Coronary Heart Disease
Hypertension
Anatomy
Body Fluids
Blood
Blood Flow
Physiology
Heart Rate
Renal Physiology
Glomerular Filtration Rate
Aged
Angiotensin-Converting Enzyme Inhibitors/administration & dosage
Blood Flow Velocity/drug effects
Blood Pressure/drug effects
Coronary Circulation/drug effects
Double-Blind Method
Female
Follow-Up Studies
Humans
Microcirculation/drug effects
Microvascular Angina/drug therapy
Middle Aged
Ramipril/administration & dosage
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Źródło :
PLoS ONE, Vol 13, Iss 6, p e0196962 (2018)
Crossref
PLoS ONE
Michelsen, M M, Rask, A B, Suhrs, E, Raft, K F, Høst, N & Prescott, E 2018, ' Effect of ACE-inhibition on coronary microvascular function and symptoms in normotensive women with microvascular angina : A randomized placebo-controlled trial ', PLOS ONE, vol. 13, no. 6, e0196962 . https://doi.org/10.1371/journal.pone.0196962
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84786b530b3eb262316a1109daeb525b
http://europepmc.org/articles/PMC5993253?pdf=render
Tytuł :
Geneva Cocktail for Cytochrome P450 and P-Glycoprotein Activity Assessment Using Dried Blood Spots
Autorzy :
Bosilkovska Weisskopf, Marija
Samer, Caroline Flora
Deglon, Julien
Rebsamen, Michela
Staub, Christian
Dayer, Pierre
Walder, Bernhard
Desmeules, Jules Alexandre
Daali, Youssef
Pokaż więcej
Temat :
Articles
Administration, Oral
Adult
Bupropion/administration & dosage
Bupropion/blood
Caffeine/administration & dosage
Caffeine/blood
Capsules
Carbonated Beverages
Chromatography, High Pressure Liquid
Chromatography, Reverse-Phase
Coffee
Cytochrome P-450 Enzyme System/antagonists & inhibitors
Cytochrome P-450 Enzyme System/blood
Dextromethorphan/administration & dosage
Dextromethorphan/blood
Dried Blood Spot Testing
Enzyme Inhibitors/administration & dosage
Feasibility Studies
Flurbiprofen/administration & dosage
Flurbiprofen/blood
Humans
Isoenzymes
Male
Midazolam/administration & dosage
Midazolam/blood
Omeprazole/administration & dosage
Omeprazole/blood
P-Glycoprotein/antagonists & inhibitors
P-Glycoprotein/blood
Pharmaceutical Preparations/administration & dosage
Pharmaceutical Preparations/blood
Phenotype
Pilot Projects
Predictive Value of Tests
Spectrometry, Mass, Electrospray Ionization
Substrate Specificity
Tandem Mass Spectrometry
Terfenadine/administration & dosage
Terfenadine/analogs & derivatives
Young Adult
Pharmacology (medical)
Pharmacology
CYP1A2
CYP2D6
Chemistry
CYP2B6
Pharmacokinetics
CYP3A
Chromatography
Dried blood spot
Terfenadine
medicine.drug
medicine
Dextromethorphan
ddc:576
ddc:617
ddc:614.1
Źródło :
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, vol. 96, no. 3, pp. 349-359
Crossref
Clinical Pharmacology and Therapeutics, Vol. 96, No 3 (2014) pp. 349-359
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02991b8cc9c7ce6a6e9158163f432b7e
http://europepmc.org/articles/PMC4151019
Tytuł :
Blockade of vascular adhesion protein-1 attenuates choroidal neovascularization
Autorzy :
Yoshikawa, Nami
Noda, Kousuke
Ozawa, Yoko
Tsubota, Kazuo
Mashima, Yukihiko
Ishida, Susumu
Pokaż więcej
Temat :
Research Article
Amine Oxidase (Copper-Containing)/antagonists & inhibitors
Amine Oxidase (Copper-Containing)/metabolism
Animals
Cell Adhesion Molecules/antagonists & inhibitors
Cell Adhesion Molecules/metabolism
Cell Movement/drug effects
Chemokine CCL2/genetics
Chemokine CCL2/metabolism
Choroid/blood supply
Choroid/drug effects
Choroid/metabolism
Choroidal Neovascularization/drug therapy
Choroidal Neovascularization/metabolism
Dose-Response Relationship, Drug
Enzyme Inhibitors/administration & dosage
Enzyme Inhibitors/therapeutic use
Gene Expression
Intercellular Adhesion Molecule-1/genetics
Intercellular Adhesion Molecule-1/metabolism
Lasers
Macrophages/drug effects
Male
Mice
Mice, Inbred C57BL
P-Selectin/genetics
P-Selectin/metabolism
Retinal Pigment Epithelium/blood supply
Retinal Pigment Epithelium/drug effects
Retinal Pigment Epithelium/metabolism
Signal Transduction/drug effects
Thiazoles/administration & dosage
Thiazoles/therapeutic use
Vascular Endothelial Growth Factor A/genetics
Vascular Endothelial Growth Factor A/metabolism
eye diseases
sense organs
genetic structures
respiratory tract diseases
Źródło :
Molecular Vision
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27bd1856fe6ce8bf673ab285e7d04279
http://europepmc.org/articles/PMC3298450
Tytuł :
Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients
Autorzy :
Jason A. Zell
Eugene W. Gerner
Patricia A. Thompson
Wen-Pin Chen
Christine E. McLaren
Frank L. Meyskens
Pokaż więcej
Temat :
Adenoma/enzymology/*genetics/*prevention & control
Aged
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Colorectal Neoplasms/enzymology/*genetics/*prevention & control
Confounding Factors
Eflornithine/administration & dosage
Enzyme Inhibitors/administration & dosage
Gene Frequency
Polymorphism, Single Nucleotide
Proteins/*genetics
Sulindac/administration & dosage
Treatment Outcome
Oncology and Carcinogenesis
Oncology & Carcinogenesis
Cancer Research
Oncology
Colorectal adenoma
medicine.disease
medicine
Genotype
Internal medicine
medicine.medical_specialty
Endocrinology
Ototoxicity
Fisher's exact test
symbols.namesake
symbols
Gastroenterology
Eflornithine
medicine.drug
Aspirin
Adenoma
business.industry
business
Placebo
Brief Communication
Źródło :
Zell, JA; McLaren, CE; Chen, W; Thompson, PA; Gerner, EW; & Meyskens, FL. (2010). Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients. Journal of the National Cancer Institute, 102(19), 1513-1516. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4tb1839b
Crossref
Zell, JA; McLaren, CE; Chen, WP; Thompson, PA; Gerner, EW; & Meyskens, FL. (2010). Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients. Journal of the National Cancer Institute, 102(19), 1513-1516. doi: 10.1093/jnci/djq325. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7ts8w7vs
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729b9318177c765c6b4a9137f2b5ea39
http://www.escholarship.org/uc/item/4tb1839b

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