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Wyszukujesz frazę ""Enzyme Inhibitors chemistry"" wg kryterium: Temat


Tytuł :
Small-molecules that covalently react with a human prolyl hydroxylase-towards activity modulation and substrate capture
Autorzy :
Bush, JT
Lesniak, RK
Yeh, TL
Belle, R
Kramer, H
Tumber, A
Chowdhury, R
Flashman, E
Mecinovic, J
Schofield, CJ
Pokaż więcej
Temat :
Ligands
Lysine/chemistry
Hippurates/chemistry
Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors
Azides/chemistry
Catalysis
Ultraviolet Rays
Protein Binding
Catalytic Domain
HeLa Cells
Humans
Enzyme Inhibitors/chemistry
Źródło :
Bush, J T, Leśniak, R K, Yeh, T L, Belle, R, Kramer, H, Tumber, A, Chowdhury, R, Flashman, E, Mecinović, J & Schofield, C J 2019, ' Small-molecules that covalently react with a human prolyl hydroxylase-towards activity modulation and substrate capture ', Chemical Communications, vol. 55, no. 8, pp. 1020-1023 . https://doi.org/10.1039/c8cc07706a
Opis pliku :
application/pdf
Tytuł :
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
Autorzy :
Manara, Maria Cristina
Valente, Sergio
Cristalli, Camilla
Nicoletti, Giordano
Landuzzi, Lorena
Zwergel, Clemens
Mazzone, Roberta
Stazi, Giulia
Arimondo, Paola
Pasello, Michela
Guerzoni, Clara
Picci, Piero
Nanni, Patrizia
Lollini, Pier-Luigi
Mai, Antonello
Scotlandi, Katia
Pokaż więcej
Temat :
MESH: Animals
MESH: Osteosarcoma/drug therapy
MESH: Osteosarcoma/metabolism
MESH: Quinolines/chemistry
MESH: Male
MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics
MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use
DNA Methyltransferase Inhibitor
MESH: Osteosarcoma/genetics
MESH: Aminoquinolines/pharmacology
MESH: Tumor Burden/genetics
chemotherapy
epigenetics
MESH: Aminoquinolines/administration & dosage
MESH: Doxorubicin/administration & dosage
MESH: Enzyme Inhibitors/chemistry
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH: Bone Neoplasms/drug therapy
MESH: Enzyme Inhibitors/administration & dosage
MESH: Enzyme Inhibitors/pharmacology
MESH: Xenograft Model Antitumor Assays
MESH: Bone Neoplasms/genetics
MESH: Benzamides/pharmacology
MESH: Tumor Burden/drug effects
MESH: Cisplatin/administration & dosage
MESH: Humans
MESH: Bone Neoplasms/metabolism
DNA methylation
MESH: Gene Expression Regulation, Neoplastic/drug effects
patient-derived xenograft (PDX)
MESH: Mice, Knockout
MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors
MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism
MESH: Benzamides/administration & dosage
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
osteosarcoma
MESH: Cell Line, Tumor
Źródło :
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Opis pliku :
STAMPA
Tytuł :
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
Autorzy :
Manara, Maria Cristina
Valente, Sergio
Cristalli, Camilla
Nicoletti, Giordano
Landuzzi, Lorena
Zwergel, Clemens
Mazzone, Roberta
Stazi, Giulia
Arimondo, Paola
Pasello, Michela
Guerzoni, Clara
Picci, Piero
Nanni, Patrizia
Lollini, Pier-Luigi
Mai, Antonello
Scotlandi, Katia
Pokaż więcej
Temat :
MESH: Aminoquinolines/administration & dosage
MESH: Aminoquinolines/pharmacology
MESH: Cisplatin/administration & dosage
MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors
MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics
MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism
MESH: Doxorubicin/administration & dosage
MESH: Enzyme Inhibitors/administration & dosage
MESH: Enzyme Inhibitors/chemistry
MESH: Enzyme Inhibitors/pharmacology
MESH: Gene Expression Regulation, Neoplastic/drug effects
MESH: Humans
MESH: Animals
MESH: Male
MESH: Mice, Knockout
MESH: Osteosarcoma/drug therapy
MESH: Osteosarcoma/genetics
MESH: Osteosarcoma/metabolism
MESH: Quinolines/chemistry
MESH: Tumor Burden/drug effects
MESH: Tumor Burden/genetics
MESH: Xenograft Model Antitumor Assays
MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MESH: Benzamides/administration & dosage
MESH: Benzamides/pharmacology
MESH: Bone Neoplasms/drug therapy
MESH: Bone Neoplasms/genetics
MESH: Bone Neoplasms/metabolism
MESH: Cell Line, Tumor
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.CAN]Life Sciences [q-bio]/Cancer
Źródło :
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩

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