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Wyszukujesz frazę ""Enzyme Inhibitors pharmacology"" wg kryterium: Temat


Tytuł :
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
Autorzy :
Manara, Maria Cristina
Valente, Sergio
Cristalli, Camilla
Nicoletti, Giordano
Landuzzi, Lorena
Zwergel, Clemens
Mazzone, Roberta
Stazi, Giulia
Arimondo, Paola
Pasello, Michela
Guerzoni, Clara
Picci, Piero
Nanni, Patrizia
Lollini, Pier-Luigi
Mai, Antonello
Scotlandi, Katia
Pokaż więcej
Temat :
MESH: Animals
MESH: Osteosarcoma/drug therapy
MESH: Osteosarcoma/metabolism
MESH: Quinolines/chemistry
MESH: Male
MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics
MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use
DNA Methyltransferase Inhibitor
MESH: Osteosarcoma/genetics
MESH: Aminoquinolines/pharmacology
MESH: Tumor Burden/genetics
chemotherapy
epigenetics
MESH: Aminoquinolines/administration & dosage
MESH: Doxorubicin/administration & dosage
MESH: Enzyme Inhibitors/chemistry
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH: Bone Neoplasms/drug therapy
MESH: Enzyme Inhibitors/administration & dosage
MESH: Enzyme Inhibitors/pharmacology
MESH: Xenograft Model Antitumor Assays
MESH: Bone Neoplasms/genetics
MESH: Benzamides/pharmacology
MESH: Tumor Burden/drug effects
MESH: Cisplatin/administration & dosage
MESH: Humans
MESH: Bone Neoplasms/metabolism
DNA methylation
MESH: Gene Expression Regulation, Neoplastic/drug effects
patient-derived xenograft (PDX)
MESH: Mice, Knockout
MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors
MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism
MESH: Benzamides/administration & dosage
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
osteosarcoma
MESH: Cell Line, Tumor
Źródło :
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Opis pliku :
STAMPA
Tytuł :
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy
Autorzy :
Manara, Maria Cristina
Valente, Sergio
Cristalli, Camilla
Nicoletti, Giordano
Landuzzi, Lorena
Zwergel, Clemens
Mazzone, Roberta
Stazi, Giulia
Arimondo, Paola
Pasello, Michela
Guerzoni, Clara
Picci, Piero
Nanni, Patrizia
Lollini, Pier-Luigi
Mai, Antonello
Scotlandi, Katia
Pokaż więcej
Temat :
MESH: Aminoquinolines/administration & dosage
MESH: Aminoquinolines/pharmacology
MESH: Cisplatin/administration & dosage
MESH: DNA (Cytosine-5-)-Methyltransferase 1/antagonists & inhibitors
MESH: DNA (Cytosine-5-)-Methyltransferase 1/genetics
MESH: DNA (Cytosine-5-)-Methyltransferase 1/metabolism
MESH: Doxorubicin/administration & dosage
MESH: Enzyme Inhibitors/administration & dosage
MESH: Enzyme Inhibitors/chemistry
MESH: Enzyme Inhibitors/pharmacology
MESH: Gene Expression Regulation, Neoplastic/drug effects
MESH: Humans
MESH: Animals
MESH: Male
MESH: Mice, Knockout
MESH: Osteosarcoma/drug therapy
MESH: Osteosarcoma/genetics
MESH: Osteosarcoma/metabolism
MESH: Quinolines/chemistry
MESH: Tumor Burden/drug effects
MESH: Tumor Burden/genetics
MESH: Xenograft Model Antitumor Assays
MESH: Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MESH: Benzamides/administration & dosage
MESH: Benzamides/pharmacology
MESH: Bone Neoplasms/drug therapy
MESH: Bone Neoplasms/genetics
MESH: Bone Neoplasms/metabolism
MESH: Cell Line, Tumor
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.CAN]Life Sciences [q-bio]/Cancer
Źródło :
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Tytuł :
Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney
Autorzy :
Zachar, Rikke
Al-Mashhadi, Ammar
Dimke, Henrik
Svenningsen, Per
Jensen, Boye L
Carlström, Mattias
Pokaż więcej
Temat :
Hydronephrosis
Captopril/pharmacology
Renin-Angiotensin System/drug effects
Angiotensin-Converting Enzyme Inhibitors/pharmacology
Hydronephrosis/etiology
Sodium/urine
NCC
Solute Carrier Family 12, Member 3/metabolism
Ureteral Obstruction/complications
Animals
Rats, Sprague-Dawley
Fibrinolysin/urine
Case-Control Studies
ENaC
Antihypertensive Agents/pharmacology
Hypertension/drug therapy
Kidney/drug effects
Up-Regulation
Disease Models, Animal
Epithelial Sodium Channels/metabolism
Blood Pressure/drug effects
Plasmin
Albuminuria/etiology
urogenital system
Humans
Male
Źródło :
Zachar, R, Al-Mashhadi, A, Dimke, H, Svenningsen, P, Jensen, B L & Carlström, M 2018, ' Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney ', American Journal of Physiology: Renal Physiology, vol. 315, no. 3, pp. F547-F557 . https://doi.org/10.1152/ajprenal.00635.2017
Opis pliku :
application/pdf
Tytuł :
The Anabolic Androgenic Steroid Fluoxymesterone Inhibits 11β-Hydroxysteroid Dehydrogenase 2-Dependent Glucocorticoid Inactivation
Autorzy :
Fürstenberger, C.
Vuorinen, A.
Da Cunha, T.
Kratschmar, D.V.
Saugy, M.
Schuster, D.
Odermatt, A.
Pokaż więcej
Temat :
11-beta-Hydroxysteroid Dehydrogenase Type 2/antagonists & inhibitors
Anabolic Agents/toxicity
Animals
Cell Line
Enzyme Inhibitors/pharmacology
Fluoxymesterone/toxicity
Glucocorticoids/antagonists & inhibitors
Humans
Mice
Źródło :
Toxicological Sciences : An Official Journal of the Society of Toxicology, vol. 126, no. 2, pp. 353-361
Opis pliku :
application/pdf

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