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Wyszukujesz frazę ""Eosinophils"" wg kryterium: Temat


Tytuł :
Identification of inflammatory markers in eosinophilic cells of the immune system: fluorescence, Raman and CARS imaging can recognize markers but differently.
Autorzy :
Borek-Dorosz A; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Krakow, Poland.; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland.
Grosicki M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland.
Dybas J; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland.
Matuszyk E; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland.
Rodewald M; Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich-Schiller-University, Helmholtzweg 4, Jena, Germany.; Leibniz Institute of Photonic Technology e.V., Member of Leibniz Health Technologies, Albert-Einstein-Str. 9, Jena, Germany.
Meyer-Zedler T; Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich-Schiller-University, Helmholtzweg 4, Jena, Germany.; Leibniz Institute of Photonic Technology e.V., Member of Leibniz Health Technologies, Albert-Einstein-Str. 9, Jena, Germany.
Schmitt M; Leibniz Institute of Photonic Technology e.V., Member of Leibniz Health Technologies, Albert-Einstein-Str. 9, Jena, Germany.
Popp J; Institute of Physical Chemistry (IPC) and Abbe Center of Photonics (ACP), Friedrich-Schiller-University, Helmholtzweg 4, Jena, Germany.; Leibniz Institute of Photonic Technology e.V., Member of Leibniz Health Technologies, Albert-Einstein-Str. 9, Jena, Germany.
Malek K; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Krakow, Poland. .
Baranska M; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Krakow, Poland. .; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Dec 22; Vol. 79 (1), pp. 52. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*metabolism
Eosinophils/*metabolism
Inflammation/*immunology
Cells, Cultured ; Eosinophils/cytology ; Humans
Czasopismo naukowe
Tytuł :
Unusual Secretion of Eosinophil Mediators Induced by Benralizumab.
Autorzy :
Cañas JA; Immunology Department, Instituto de Investigación Sanitaria (IIS) Fundación Jiménez Díaz, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
Valverde-Monge M; Allergy Unit, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Rodríguez-Nieto M; Pneumology Unit, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
González-Mangado N; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Pneumology Unit, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Sastre J; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Allergy Unit, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Del Pozo V; Immunology Department, Instituto de Investigación Sanitaria (IIS) Fundación Jiménez Díaz, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
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Źródło :
Journal of investigational allergology & clinical immunology [J Investig Allergol Clin Immunol] 2021 Dec 21; Vol. 31 (6), pp. 513-515. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Asthmatic Agents*
Eosinophils*
Antibodies, Monoclonal, Humanized ; Humans ; Leukocyte Count
Czasopismo naukowe
Tytuł :
CCAAT/Enhancer-Binding Protein ε Antagonism of GATA-1 Transcriptional Activity in the Eosinophil Is Mediated by a Unique N-Terminal Repression Domain, Is Independent of Sumoylation and Does Not Require DNA Binding.
Autorzy :
Stankiewicz MJ; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.; UW Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Du J; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Martinico D; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.; College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
Ackerman SJ; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 24; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Sumoylation*
CCAAT-Enhancer-Binding Proteins/*metabolism
Eosinophils/*pathology
GATA1 Transcription Factor/*antagonists & inhibitors
Leukemia, Myeloid, Acute/*pathology
Myelin Basic Protein/*metabolism
CCAAT-Enhancer-Binding Proteins/genetics ; Cell Differentiation ; Cell Nucleus ; Eosinophils/immunology ; Eosinophils/metabolism ; GATA1 Transcription Factor/genetics ; GATA1 Transcription Factor/metabolism ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/immunology ; Leukemia, Myeloid, Acute/metabolism ; Myelin Basic Protein/genetics ; Promoter Regions, Genetic ; Protein Interaction Domains and Motifs ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Bilateral Posterior Auricular Masses: A Case of Kimura's Disease.
Autorzy :
Xie F; Department of Otorhinolaryngology Head and Neck Surgery, Cheeloo College of Medicine, 34708Shandong Provincial Hospital, Shandong University, Jinan, China.
Kou Y; Neonatal Department, The First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Zhang S; Department of Pathology, 34708Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Shi L; Department of Otolaryngology-Head and Neck Surgery, Cheeloo College of Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, China.
Han J; Department of Otorhinolaryngology Head and Neck Surgery, Cheeloo College of Medicine, 34708Shandong Provincial Hospital, Shandong University, Jinan, China.
Zhou X; Department of Otorhinolaryngology Head and Neck Surgery, 34708Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
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Źródło :
Ear, nose, & throat journal [Ear Nose Throat J] 2021 Nov; Vol. 100 (9), pp. 634-637. Date of Electronic Publication: 2021 Sep 18.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Eosinophils*
Kimura Disease/*surgery
Homocysteine/blood ; Humans ; Kimura Disease/blood ; Kimura Disease/diagnosis ; Kimura Disease/pathology ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Increased MMP12 mRNA expression in induced sputum was correlated with airway eosinophilic inflammation in asthma patients: Evidence from bioinformatic analysis and experiment verification.
Autorzy :
Du L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Chen F; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Xu C; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Tan W; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Shi J; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Tang L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Xiao L; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Xie C; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China.
Zeng Z; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China. Electronic address: .
Liang Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China. Electronic address: .
Guo Y; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China; Institute of Respiratory Diseases of Sun Yat-Sen University, No. 58 Zhongshan 2nd Road, Guangzhou 510080, Guangdong, China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Dec 15; Vol. 804, pp. 145896. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma/*genetics
Eosinophils/*metabolism
Matrix Metalloproteinase 12/*genetics
Adult ; Asthma/physiopathology ; Biomarkers/metabolism ; Computational Biology/methods ; Databases, Genetic ; Eosinophils/immunology ; Female ; Gene Expression ; Gene Expression Profiling/methods ; Humans ; Inflammation/genetics ; Inflammation/immunology ; Male ; Matrix Metalloproteinase 12/metabolism ; RNA, Messenger/metabolism ; Sputum/metabolism
Czasopismo naukowe
Tytuł :
Asymmetrical cutaneous vasculitis following COVID-19 vaccination with unusual eosinophil preponderance.
Autorzy :
Kharkar V; Department of Dermatology, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, India.
Vishwanath T; Department of Dermatology, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, India.
Mahajan S; Department of Dermatology, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, India.
Joshi R; Department of Dermatology, P. D. Hinduja National Hospital and Medical Research Centre, Mumbai, India.
Gole P; Department of Dermatology, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, India.
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Źródło :
Clinical and experimental dermatology [Clin Exp Dermatol] 2021 Dec; Vol. 46 (8), pp. 1596-1597. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
COVID-19/*prevention & control
COVID-19 Vaccines/*adverse effects
Eosinophils/*immunology
Skin Diseases, Vascular/*chemically induced
Vasculitis, Leukocytoclastic, Cutaneous/*etiology
Adult ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/immunology ; Dermoscopy/methods ; Eosinophils/pathology ; Female ; Histamine Antagonists/therapeutic use ; Humans ; Purpura/diagnosis ; Purpura/etiology ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; Skin Diseases, Vascular/pathology ; Treatment Outcome ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis
Raport
Tytuł :
Asthma Phenotyping in Primary Care: Applying the International Severe Asthma Registry Eosinophil Phenotype Algorithm Across All Asthma Severities.
Autorzy :
Kerkhof M; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Tran TN; AstraZeneca, Gaithersburg, Md.
Allehebi R; Department of Pulmonology, King Fahad Medical City, Riyadh, Saudi Arabia.
Canonica GW; Personalized Medicine Asthma and Allergy Clinic, Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Heaney LG; UK Severe Asthma Network and National Registry Centre and Centre for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.
Hew M; Allergy, Asthma, and Clinical Immunology Service, Alfred Health, Melbourne, Australia; Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Perez de Llano L; Department of Respiratory Medicine, Hospital Universitario Lucus Augusti, Lugo, Spain.
Wechsler ME; NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, Colo.
Bulathsinhala L; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Carter VA; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Chaudhry I; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Eleangovan N; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Murray RB; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Price CA; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom.
Price DB; Observational and Pragmatic Research Institute, Singapore, Singapore; Optimum Patient Care, Cambridge, United Kingdom; Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom. Electronic address: .
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Źródło :
The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2021 Dec; Vol. 9 (12), pp. 4353-4370. Date of Electronic Publication: 2021 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma*/diagnosis
Asthma*/epidemiology
Eosinophils*
Adolescent ; Algorithms ; Humans ; Leukocyte Count ; Phenotype ; Primary Health Care ; Registries ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Blood Eosinophils and Pulmonary Rehabilitation in COPD.
Autorzy :
Aljazeeri J; University of Pittsburgh Medical Center, Pennsylvania, USA.; Drexel University College of Medicine, Pennsylvania, USA.
Sakkat A; McMaster University, Department of Medicine, Division of Respirology, Hamilton, Canada.
Makhdami N; Firestone Institute for Respiratory Health, St Joseph Healthcare, Hamilton, Canada.
Almusally R; Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Morfaw F; McMaster Univerisity, Department of Health Research Methods, Evidence and Impact, Hamilton, Canada.
McIvor A; McMaster University, Department of Medicine, Division of Respirology, Hamilton, Canada.; Firestone Institute for Respiratory Health, St Joseph Healthcare, Hamilton, Canada.
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Źródło :
Canadian respiratory journal [Can Respir J] 2021 Nov 05; Vol. 2021, pp. 7449527. Date of Electronic Publication: 2021 Nov 05 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Eosinophils*
Pulmonary Disease, Chronic Obstructive*
Humans ; Lung ; Retrospective Studies ; Severity of Illness Index ; Walk Test
Czasopismo naukowe
Tytuł :
An Unexpected Line of Defense: Hepatoprotective Eosinophils in Ischemia-Reperfusion Injury.
Autorzy :
Peiseler M; Department of Hepatology & Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.; Berlin Institute of Health, Berlin, Germany.
Tacke F; Department of Hepatology & Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.
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Źródło :
Hepatology (Baltimore, Md.) [Hepatology] 2021 Nov; Vol. 74 (5), pp. 2888-2890. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Eosinophils/*transplantation
Graft Rejection/*prevention & control
Liver Transplantation/*adverse effects
Reperfusion Injury/*immunology
Adoptive Transfer/methods ; Allografts/blood supply ; Allografts/immunology ; Allografts/pathology ; Animals ; Disease Models, Animal ; Disease Susceptibility/immunology ; Donor Selection/standards ; Eosinophils/immunology ; Graft Rejection/immunology ; Graft Rejection/pathology ; Humans ; Liver/blood supply ; Liver/immunology ; Liver/pathology ; Liver Transplantation/standards ; Mice ; Reperfusion Injury/pathology ; Reperfusion Injury/therapy
Czasopismo naukowe
Tytuł :
Diagnoses associated with peripheral blood eosinophilia: A 5-year review.
Autorzy :
Leverone N; Department of Medicine, University of California San Diego Health, San Diego, California; Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California San Diego Health, San Diego, California.
Tran S; Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California San Diego Health, San Diego, California.
Barry J; Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California San Diego Health, San Diego, California.
Akuthota P; Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California San Diego Health, San Diego, California. Electronic address: .
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Źródło :
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2021 Nov; Vol. 127 (5), pp. 597-598. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Letter
MeSH Terms :
Eosinophilia/*diagnosis
Eosinophilia/*pathology
Eosinophils/*immunology
Adult ; Asthma/drug therapy ; Asthma/pathology ; Churg-Strauss Syndrome/drug therapy ; Churg-Strauss Syndrome/pathology ; Eosinophilia/drug therapy ; Eosinophils/cytology ; Humans ; Hypereosinophilic Syndrome/drug therapy ; Hypereosinophilic Syndrome/pathology ; Interleukin-5/antagonists & inhibitors
Opinia redakcyjna
Tytuł :
Neutrophils, eosinophils, and intraepithelial lymphocytes in the squamous esophagus in subjects with and without gastroesophageal reflux symptoms.
Autorzy :
Zand Irani M; University of Newcastle, Newcastle, Australia; Hunter Medical Research Institute, New Lambton Heights, Australia.
Talley NJ; University of Newcastle, Newcastle, Australia; Hunter Medical Research Institute, New Lambton Heights, Australia; NHMRC Centre of Research Excellence in Digestive Health. Electronic address: .
Ronkainen J; Center for Life Course Health Research, University of Oulu, Finland; Primary Health Care Centre, Tornio, Finland.
Aro P; Arokero OY, Tornio, Finland.
Andreasson A; Department of Psychology, Macquarie University, North Ryde, Australia; Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden; Department of Medicine Solna, Karolinska Institutet, Sweden.
Agreus L; Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Vieth M; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Klinikum Bayreuth, Bayreuth, Germany.
Jones MP; NHMRC Centre of Research Excellence in Digestive Health; Department of Psychology, Macquarie University, North Ryde, Australia.
Walker MM; University of Newcastle, Newcastle, Australia; NHMRC Centre of Research Excellence in Digestive Health.
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Źródło :
Human pathology [Hum Pathol] 2021 Sep; Vol. 115, pp. 112-122. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Eosinophils*/cytology
Eosinophils*/pathology
Intraepithelial Lymphocytes*/cytology
Intraepithelial Lymphocytes*/pathology
Neutrophils*/cytology
Neutrophils*/pathology
Esophageal Mucosa/*cytology
Esophageal Mucosa/*pathology
Gastroesophageal Reflux/*pathology
Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Reference Values
Czasopismo naukowe
Tytuł :
Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro .
Autorzy :
Carroll DJ; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Cao Y; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Bochner BS; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
O'Sullivan JA; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Oct 11; Vol. 12, pp. 737988. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antigens, CD/*metabolism
Antigens, Differentiation, B-Lymphocyte/*metabolism
Eosinophils/*metabolism
Lectins/*metabolism
Agammaglobulinaemia Tyrosine Kinase/metabolism ; CD11b Antigen/metabolism ; Cell Death ; Cells, Cultured ; Eosinophils/drug effects ; Eosinophils/immunology ; Eosinophils/pathology ; Humans ; Interleukin-5/pharmacology ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases/metabolism ; Protein Kinase C/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Syk Kinase/metabolism ; Type C Phospholipases/metabolism ; p21-Activated Kinases/metabolism ; src-Family Kinases/metabolism
Czasopismo naukowe
Tytuł :
The JAK1/2 inhibitor baricitinib suppresses eosinophil effector function and restricts allergen-induced airway eosinophilia.
Autorzy :
Luschnig P; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Kienzl M; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria; BioTechMed, Graz, Austria.
Roula D; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Pilic J; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Atallah R; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Heinemann A; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria.
Sturm EM; Otto-Loewi Research Center for Vascular Biology, Immunology and Inflammation, Division of Pharmacology, Medical University of Graz, Graz, Austria. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114690. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Azetidines/*therapeutic use
Eosinophilia/*drug therapy
Eosinophils/*drug effects
Janus Kinase 1/*antagonists & inhibitors
Janus Kinase 2/*antagonists & inhibitors
Janus Kinase Inhibitors/*therapeutic use
Purines/*therapeutic use
Pyrazoles/*therapeutic use
Sulfonamides/*therapeutic use
Adult ; Animals ; Azetidines/pharmacology ; Cells, Cultured ; Eosinophilia/chemically induced ; Eosinophilia/immunology ; Eosinophils/physiology ; Female ; Humans ; Janus Kinase 1/immunology ; Janus Kinase 2/immunology ; Janus Kinase Inhibitors/pharmacology ; Male ; Mice ; Mice, Inbred BALB C ; Purines/pharmacology ; Pyrazoles/pharmacology ; Pyroglyphidae/immunology ; Sulfonamides/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł :
Eosinophils and activation markers after allergen challenge - a pilot study for three-dimensional analysis in the bronchial mucosa.
Autorzy :
Prenzler F; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
Tschernig T; Institute for Cell Biology and Anatomy, Saarland University, Saarbrucken, Germany.
Sewald K; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Member of the German Center for Lung Research (DZL), Biomedical Research in End-stage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.
Veres TZ; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Rittinghausen S; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Member of the German Center for Lung Research (DZL), Biomedical Research in End-stage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.
Krug N; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Member of the German Center for Lung Research (DZL), Biomedical Research in End-stage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.
Hohlfeld JM; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Member of the German Center for Lung Research (DZL), Biomedical Research in End-stage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Braun A; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.; Member of the German Center for Lung Research (DZL), Biomedical Research in End-stage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.; Institute of Immunology, Hannover Medical School, Hannover, Germany.
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Źródło :
Allergy [Allergy] 2021 Sep; Vol. 76 (9), pp. 2907-2910. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Bronchial Hyperreactivity*
Eosinophils*
Allergens ; Bronchi/diagnostic imaging ; Bronchial Provocation Tests ; Bronchoalveolar Lavage Fluid ; Humans ; Mucous Membrane ; Pilot Projects
Raport
Tytuł :
miR-100-5p in human umbilical cord mesenchymal stem cell-derived exosomes mediates eosinophilic inflammation to alleviate atherosclerosis via the FZD5/Wnt/β-catenin pathway.
Autorzy :
Gao H; Department of Emergency Internal Medicine, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
Yu Z; Department of Cardiovascular Medicine, Qingyang People's Hospital, Qingyang 745000, China.
Li Y; Department of Emergency Surgery, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
Wang X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2021 Aug 31; Vol. 53 (9), pp. 1166-1176.
Typ publikacji :
Journal Article
MeSH Terms :
Atherosclerosis/*genetics
Eosinophils/*metabolism
Exosomes/*immunology
Frizzled Receptors/*metabolism
Mesenchymal Stem Cells/*chemistry
MicroRNAs/*immunology
Wnt Signaling Pathway/*genetics
Animals ; Apoptosis/genetics ; Cell Movement/genetics ; Eosinophils/pathology ; Exosomes/chemistry ; Exosomes/metabolism ; Female ; Frizzled Receptors/genetics ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Lipoproteins, LDL/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Umbilical Cord/cytology ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production.
Autorzy :
Yadav B; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Specht CA; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Lee CK; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Pokrovskii M; The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York, United States of America.
Huh JR; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America.; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Littman DR; The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York, United States of America.; Howard Hughes Medical Institute, New York, New York, United States of America.
Levitz SM; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Aug 31; Vol. 17 (8), pp. e1009891. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Eosinophils/*immunology
Hypersensitivity/*immunology
Interleukin-17/*metabolism
Interleukin-23/*physiology
Nuclear Receptor Subfamily 1, Group F, Member 3/*physiology
Pulmonary Aspergillosis/*immunology
Receptors, Interleukin/*metabolism
Animals ; Eosinophils/metabolism ; Eosinophils/pathology ; Hypersensitivity/metabolism ; Hypersensitivity/pathology ; Interleukin-17/genetics ; Lung/immunology ; Lung/metabolism ; Lung/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pulmonary Aspergillosis/metabolism ; Pulmonary Aspergillosis/pathology ; Receptors, Interleukin/genetics
Czasopismo naukowe
Tytuł :
Behavior of Eosinophil Counts in Recovered and Deceased COVID-19 Patients over the Course of the Disease.
Autorzy :
Cortés-Vieyra R; Centro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social (IMSS), Morelia 58341, Michoacán, Mexico.
Gutiérrez-Castellanos S; Centro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social (IMSS), Morelia 58341, Michoacán, Mexico.; División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas 'Dr. Ignacio Chávez', Universidad Michoacana de San Nicolás de Hidalgo (UMSNH), Morelia 58020, Michoacán, Mexico.
Álvarez-Aguilar C; División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas 'Dr. Ignacio Chávez', Universidad Michoacana de San Nicolás de Hidalgo (UMSNH), Morelia 58020, Michoacán, Mexico.; Coordinación Auxiliar Médica de Investigación en Salud, IMSS, Morelia 58000, Michoacán, Mexico.
Baizabal-Aguirre VM; Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, UMSNH, Morelia 58890, Michoacán, Mexico.
Nuñez-Anita RE; Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, UMSNH, Morelia 58890, Michoacán, Mexico.
Rocha-López AG; División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas 'Dr. Ignacio Chávez', Universidad Michoacana de San Nicolás de Hidalgo (UMSNH), Morelia 58020, Michoacán, Mexico.
Gómez-García A; Centro de Investigación Biomédica de Michoacán, División de Investigación Clínica, Instituto Mexicano del Seguro Social (IMSS), Morelia 58341, Michoacán, Mexico.
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Źródło :
Viruses [Viruses] 2021 Aug 24; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Eosinophils*/immunology
Host-Pathogen Interactions*/immunology
Leukocyte Count*
SARS-CoV-2*/immunology
COVID-19/*blood
COVID-19/*virology
Adult ; Aged ; Aged, 80 and over ; Biomarkers ; COVID-19/diagnosis ; COVID-19/immunology ; Comorbidity ; Disease Progression ; Female ; Humans ; Kaplan-Meier Estimate ; Length of Stay ; Leukocytes ; Lymphocyte Count ; Lymphocytes ; Male ; Middle Aged ; Neutrophils ; Prognosis ; Retrospective Studies ; Severity of Illness Index ; Young Adult
Czasopismo naukowe
Tytuł :
Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease.
Autorzy :
Buchheit KM; Department of Medicine, Harvard Medical School, the Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Lewis E; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Gakpo D; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Hacker J; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Sohail A; Department of Medicine, Harvard Medical School, the Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Taliaferro F; Division of Gastroenterology, Boston Children's Hospital, Boston, Mass; Broad Institute of MIT and Harvard, Cambridge, Mass.
Berreondo Giron E; Division of Gastroenterology, Boston Children's Hospital, Boston, Mass.
Asare C; Division of Gastroenterology, Boston Children's Hospital, Boston, Mass.
Vukovic M; Broad Institute of MIT and Harvard, Cambridge, Mass; Ragon Institute of Massachusetts General Hospital, MIT and Harvard, Cambridge, Mass; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, MIT, Cambridge, Mass.
Bensko JC; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Dwyer DF; Department of Medicine, Harvard Medical School, the Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass.
Shalek AK; Broad Institute of MIT and Harvard, Cambridge, Mass; Ragon Institute of Massachusetts General Hospital, MIT and Harvard, Cambridge, Mass; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, MIT, Cambridge, Mass; Program in Immunology, Harvard Medical School, Boston, Mass; Harvard-MIT Division of Health Sciences & Technology, Cambridge, Mass.
Ordovas-Montanes J; Division of Gastroenterology, Boston Children's Hospital, Boston, Mass; Broad Institute of MIT and Harvard, Cambridge, Mass; Program in Immunology, Harvard Medical School, Boston, Mass; Harvard Stem Cell Institute, Cambridge, Mass.
Laidlaw TM; Department of Medicine, Harvard Medical School, the Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Mass. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 574-584. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma, Aspirin-Induced*/drug therapy
Asthma, Aspirin-Induced*/immunology
Asthma, Aspirin-Induced*/urine
Basophils*/immunology
Basophils*/pathology
Eosinophils*/immunology
Eosinophils*/pathology
Nasal Polyps*/drug therapy
Nasal Polyps*/immunology
Nasal Polyps*/urine
Antibodies, Monoclonal, Humanized/*administration & dosage
Adolescent ; Adult ; Aged ; Eicosanoids/immunology ; Eicosanoids/urine ; Female ; Humans ; Interleukin-5/immunology ; Interleukin-5 Receptor alpha Subunit/immunology ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Paeoniflorin protects against dextran sulfate sodium (DSS)-induced colitis in mice through inhibition of inflammation and eosinophil infiltration.
Autorzy :
Li J; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, China; State Key Laboratory of Pharmaceutical Biotechnology, Medical School, Nanjing University, China; Jiangsu Topcel Biological Technology Co, Ltd, Nanjing, China.
Ren S; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, China.
Li M; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, China.
Bi J; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, China.
Yang G; Nanjing Children's Hospital, Nanjing Medical University, Nanjing, China.
Li E; Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, China; State Key Laboratory of Pharmaceutical Biotechnology, Medical School, Nanjing University, China; Shenzhen Research Institute of Nanjing University, Shenzhen, China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Aug; Vol. 97, pp. 107667. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Colitis, Ulcerative/*drug therapy
Eosinophils/*drug effects
Glucosides/*pharmacology
Monoterpenes/*pharmacology
Animals ; Anti-Inflammatory Agents/therapeutic use ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/immunology ; Colitis, Ulcerative/pathology ; Colon/drug effects ; Colon/immunology ; Colon/pathology ; Dextran Sulfate/administration & dosage ; Dextran Sulfate/toxicity ; Disease Models, Animal ; Eosinophils/immunology ; Female ; Glucosides/therapeutic use ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Mice ; Monoterpenes/therapeutic use ; Paeonia/chemistry ; Signal Transduction/drug effects ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
Rethinking neutrophils and eosinophils in chronic rhinosinusitis.
Autorzy :
Delemarre T; Upper Airways Research Laboratory, Faculty of Medicine, Ghent University, Ghent, Belgium.
Bochner BS; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Simon HU; Institute of Pharmacology, University of Bern, Bern, Switzerland; the Department of Clinical Immunology and Allergology, Sechenov University, Moscow, Russia; Laboratory of Molecular Immunology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Bachert C; Upper Airways Research Laboratory, Faculty of Medicine, Ghent University, Ghent, Belgium; Division of ENT Diseases, CLINTEC, Karolinska Institute, Stockholm, Sweden; First Affiliated Hospital, Sun Yat-Sen University, International Airway Research Center, Guangzhou, China. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 327-335. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Eosinophils/*immunology
Neutrophils/*immunology
Rhinitis/*immunology
Sinusitis/*immunology
Chronic Disease ; Eosinophils/pathology ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Inflammation/therapy ; Nasal Polyps/immunology ; Nasal Polyps/pathology ; Nasal Polyps/therapy ; Neutrophils/pathology ; Rhinitis/pathology ; Rhinitis/therapy ; Severity of Illness Index ; Sinusitis/pathology ; Sinusitis/therapy
Czasopismo naukowe

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