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Tytuł:
Design principles of 3D epigenetic memory systems.
Autorzy:
Owen JA; Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA.
Osmanović D; Department of Mechanical and Aeronautical Engineering, UCLA, Los Angeles, CA, USA.
Mirny L; Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Nov 17; Vol. 382 (6672), pp. eadg3053. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Chromosomes*/metabolism
Epigenetic Memory*
Genome*
Imaging, Three-Dimensional*
Computer Simulation*
Chromatin ; Histones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reversible switching and stability of the epigenetic memory system in bacteria.
Autorzy:
Graf D; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Germany.
Laistner L; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Germany.
Klingel V; Institute for Systems Theory and Automatic Control, University of Stuttgart, Germany.
Radde NE; Institute for Systems Theory and Automatic Control, University of Stuttgart, Germany.
Weirich S; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Germany.
Jeltsch A; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Germany.
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Źródło:
The FEBS journal [FEBS J] 2023 Apr; Vol. 290 (8), pp. 2115-2126. Date of Electronic Publication: 2022 Dec 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epigenetic Memory*
Gene Expression Regulation, Bacterial*
Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/metabolism ; Bacteria/metabolism ; DNA Methylation ; DNA/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation.
Autorzy:
Hata M; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Andriessen EMMA; Department of Biomedical Sciences, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Hata M; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Diaz-Marin R; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Fournier F; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Crespo-Garcia S; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Blot G; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Juneau R; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Pilon F; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Dejda A; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Guber V; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Heckel E; Departments of Pediatrics, Ophthalmology, and Pharmacology, Centre Hospitalier Universitaire Ste-Justine Research Center, Montreal, Quebec H3T 1C5, Canada.
Daneault C; Department of Nutrition, University of Montreal, Montreal, Quebec, Plateforme métabolomique de l'Institut de Cardiologie de Montréal, Montreal, Quebec H3C 3J7, Canada.
Calderon V; Bioinformatics & Molecular Biology Core Facility, Institut de Recherches Cliniques de Montréal, Montreal, Quebec H2W 1R7, Canada.
Des Rosiers C; Department of Nutrition, University of Montreal, Montreal, Quebec, Plateforme métabolomique de l'Institut de Cardiologie de Montréal, Montreal, Quebec H3C 3J7, Canada.
Melichar HJ; Department of Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Langmann T; Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.
Joyal JS; Departments of Pediatrics, Ophthalmology, and Pharmacology, Centre Hospitalier Universitaire Ste-Justine Research Center, Montreal, Quebec H3T 1C5, Canada.
Wilson AM; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
Sapieha P; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.; Department of Biochemistry and Molecular Medicine, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Jan 06; Vol. 379 (6627), pp. 45-62. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Immunity, Innate*/genetics
Neuroinflammatory Diseases*/genetics
Neuroinflammatory Diseases*/immunology
Obesity*/genetics
Macular Degeneration*/genetics
Macular Degeneration*/immunology
Epigenetic Memory*
Animals ; Mice ; Cytokines/genetics ; Phagocytes/immunology ; Transcription, Genetic ; Cellular Reprogramming/genetics ; Toll-Like Receptor 4/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Obesity confers macrophage memory.
Autorzy:
Mangum KD; Departments of Surgery and Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
Gallagher KA; Departments of Surgery and Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Jan 06; Vol. 379 (6627), pp. 28-29. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophages*/immunology
Obesity*/genetics
Obesity*/immunology
Macular Degeneration*/genetics
Macular Degeneration*/immunology
Epigenetic Memory*
Myeloid Cells/immunology ; Cellular Reprogramming/genetics ; Animals ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epigenetic repression of antiviral genes by SARS-CoV-2 NSP1.
Autorzy:
Anastasakis DG; RNA Molecular Biology Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Benhalevy D; RNA Molecular Biology Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Çuburu N; Laboratory of Cellular Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Altan-Bonnet N; Laboratory of Host-Pathogen Dynamics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Hafner M; RNA Molecular Biology Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Jan 26; Vol. 19 (1), pp. e0297262. Date of Electronic Publication: 2024 Jan 26 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
COVID-19*/immunology
COVID-19*/virology
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/metabolism
Humans ; Epigenetic Repression ; Viral Nonstructural Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Skeletal Muscle Possesses an Epigenetic Memory of Exercise: Role of Nucleus Type-Specific DNA Methylation.
Autorzy:
Sharples AP; The Norwegian School of Sport Sciences, Institute for Physical Performance, Postboks 4014, Ullevål Stadion, 0806 Oslo, Norway.
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Źródło:
Function (Oxford, England) [Function (Oxf)] 2021 Sep 04; Vol. 2 (5), pp. zqab047. Date of Electronic Publication: 2021 Sep 04 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
DNA Methylation*/genetics
Epigenetic Memory*
Muscle, Skeletal/metabolism ; Exercise/physiology ; DNA/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Perinatal S-Adenosylmethionine Supplementation Represses PSEN1 Expression by the Cellular Epigenetic Memory of CpG and Non-CpG Methylation in Adult TgCRD8 Mice.
Autorzy:
Raia T; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Armeli F; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.
Cavallaro RA; Department of Surgery, Sapienza University of Rome, 00161 Rome, Italy.
Ferraguti G; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Businaro R; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.
Lucarelli M; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.; Pasteur Institute, Cenci Bolognetti Foundation, Sapienza University of Rome, 00161 Rome, Italy.
Fuso A; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 19; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
S-Adenosylmethionine*/metabolism
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Pregnancy ; Female ; Mice ; Animals ; Epigenetic Memory ; DNA Methylation ; Mice, Transgenic ; Dietary Supplements
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
EPHA3 Contributes to Epigenetic Suppression of PTEN in Radioresistant Head and Neck Cancer.
Autorzy:
Kim SH; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Kang BC; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Seong D; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Lee WH; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
An JH; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Je HU; Department of Radiation Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Cha HJ; Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
Chang HW; Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim SY; Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Kim SW; Department of Biochemistry and Molecular Biology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Han MW; Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.
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Źródło:
Biomolecules [Biomolecules] 2021 Apr 18; Vol. 11 (4). Date of Electronic Publication: 2021 Apr 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epigenetic Repression*
Radiation Tolerance*
Head and Neck Neoplasms/*genetics
PTEN Phosphohydrolase/*genetics
Receptor, EphA3/*genetics
Cell Line, Tumor ; DNA (Cytosine-5-)-Methyltransferase 1/genetics ; DNA (Cytosine-5-)-Methyltransferase 1/metabolism ; DNA Methylation ; Enhancer of Zeste Homolog 2 Protein/genetics ; Enhancer of Zeste Homolog 2 Protein/metabolism ; Head and Neck Neoplasms/metabolism ; Head and Neck Neoplasms/radiotherapy ; Histone Code ; Humans ; PTEN Phosphohydrolase/metabolism ; Receptor, EphA3/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
DNA Methylation-Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia.
Autorzy:
Buelow DR; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Anderson JT; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Pounds SB; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Shi L; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Lamba JK; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, Florida, USA.
Hu S; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Gibson AA; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Goodwin EA; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Sparreboom A; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Baker SD; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2021 Jan; Vol. 14 (1), pp. 137-142. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytarabine/*pharmacology
Drug Resistance, Neoplasm/*genetics
Epigenetic Repression/*genetics
Leukemia, Myeloid, Acute/*drug therapy
Organic Cation Transport Proteins/*genetics
Symporters/*genetics
Adolescent ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Azacitidine/pharmacology ; Azacitidine/therapeutic use ; Cell Line, Tumor ; Child ; Clinical Trials, Phase III as Topic ; Cytarabine/therapeutic use ; DNA Methylation/drug effects ; DNA Methylation/genetics ; Datasets as Topic ; Decitabine/pharmacology ; Decitabine/therapeutic use ; Epigenetic Repression/drug effects ; Female ; Gene Expression Regulation, Leukemic/drug effects ; HEK293 Cells ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/mortality ; Leukemia, Myeloid, Acute/pathology ; Male ; Organic Cation Transport Proteins/metabolism ; Progression-Free Survival ; Randomized Controlled Trials as Topic ; Symporters/metabolism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of epigenetic clocks links yoga, sleep, education, reduced meat intake, coffee, and a SOCS2 gene variant to slower epigenetic aging
Autorzy:
Noroozi, RezvanAff1, Aff2
Rudnicka, JoannaAff1, Aff3
Pisarek, Aleksandra
Wysocka, Bożena
Masny, Aleksander
Boroń, Michał
Migacz-Gruszka, Kamila
Pruszkowska-Przybylska, Paulina
Kobus, Magdalena
Lisman, Dagmara
Zielińska, Grażyna
Iljin, Aleksandra
Wiktorska, Joanna A.
Michalczyk, Małgorzata
Kaczka, Piotr
Krzysztofik, Michał
Sitek, Aneta
Ossowski, Andrzej
Spólnicka, Magdalena
Branicki, WojciechAff4, Aff14
Pośpiech, EwelinaAff3, Aff9, IDs11357023010294_cor21
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Źródło:
GeroScience: Official Journal of the American Aging Association (AGE). 46(2):2583-2604
Czasopismo naukowe
Szczegóły
Tytuł:
GrimAge is elevated in older adults with mild COVID-19 an exploratory analysis
Autorzy:
García-delaTorre, Paola
Rivero-Segura, Nadia Alejandra
Sánchez-García, Sergio
Becerril-Rojas, Kristhian
Sandoval-Rodriguez, Francisco Ernesto
Castro-Morales, Diana
Cruz-Lopez, Miguel
Vazquez-Moreno, Miguel
Rincón-Heredia, Ruth
Ramirez-Garcia, Perla
Gomez-Verjan, Juan CarlosAff2, IDs11357024010952_cor11
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Źródło:
GeroScience: Official Journal of the American Aging Association (AGE). :1-14
Czasopismo naukowe
Szczegóły
Tytuł:
Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain.
Autorzy:
Farley SJ; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Grishok A; Department of Biochemistry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.; Boston University Genome Science Institute, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.
Zeldich E; Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA. .
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Źródło:
Epigenetics & chromatin [Epigenetics Chromatin] 2022 Dec 03; Vol. 15 (1), pp. 39. Date of Electronic Publication: 2022 Dec 03.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Brain*/metabolism
Down Syndrome*/genetics
HMGN1 Protein*/genetics
Polycomb Repressive Complex 2*/genetics
Humans ; Chromatin/genetics ; Histones ; Lysine ; Trisomy ; Epigenetic Repression/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High Level of Gene Transcription at the Embryonic Stage Leads to the Suppression of Heterochromatic Trans-Inactivation in Drosophila melanogaster Adults.
Autorzy:
Solodovnikov AA; Institute of Molecular Genetics of the Russian Academy of Sciences, Moscow, 123182, Russia.
Gvozdev VA; Institute of Molecular Genetics of the Russian Academy of Sciences, Moscow, 123182, Russia.
Lavrov SA; Institute of Molecular Genetics of the Russian Academy of Sciences, Moscow, 123182, Russia. .
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Apr; Vol. 85 (4), pp. 472-479.
Typ publikacji:
Journal Article
MeSH Terms:
Epigenetic Repression*
Gene Silencing*
Heterochromatin*
Transcription, Genetic*
Drosophila melanogaster/*embryology
Drosophila melanogaster/*genetics
Embryonic Development/*genetics
Animals ; Genes, Reporter ; Transgenes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A central role for MeCP2 in the epigenetic repression of miR-200c during epithelial-to-mesenchymal transition of glioma.
Autorzy:
Bian E; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China.; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China.
Chen X; Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China.
Xu Y; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China.; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China.
Ji X; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China.; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China.
Cheng M; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China.; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China.
Wang H; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China.; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China.
Fang Z; Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. .
Zhao B; Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, 678 Fu Rong Road, Hefei, 230601, Anhui Province, China. .; Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, 230601, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Aug 20; Vol. 38 (1), pp. 366. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji:
Journal Article
MeSH Terms:
Epigenetic Repression*
Epithelial-Mesenchymal Transition*
Biomarkers, Tumor/*metabolism
Brain Neoplasms/*pathology
Glioma/*pathology
Methyl-CpG-Binding Protein 2/*metabolism
MicroRNAs/*genetics
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Cell Cycle ; Cell Movement ; Cell Proliferation ; Female ; Follow-Up Studies ; Gene Expression Regulation, Neoplastic ; Glioma/genetics ; Glioma/metabolism ; Humans ; Methyl-CpG-Binding Protein 2/genetics ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Prognosis ; Signal Transduction ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
OCT4 Silencing Triggers Its Epigenetic Repression and Impairs the Osteogenic and Adipogenic Differentiation of Mesenchymal Stromal Cells.
Autorzy:
Malvicini R; Laboratorio de Regulación Génica y Células Madre, Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Solís 453, Buenos Aires 1078, Argentina.
Santa-Cruz D; Laboratorio de Regulación Génica y Células Madre, Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Solís 453, Buenos Aires 1078, Argentina.
Pacienza N; Laboratorio de Regulación Génica y Células Madre, Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Solís 453, Buenos Aires 1078, Argentina.
Yannarelli G; Laboratorio de Regulación Génica y Células Madre, Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Solís 453, Buenos Aires 1078, Argentina. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jul 03; Vol. 20 (13). Date of Electronic Publication: 2019 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Adipogenesis*
Epigenetic Repression*
Osteogenesis*
Mesenchymal Stem Cells/*metabolism
Octamer Transcription Factor-3/*genetics
Animals ; DNA Methylation ; Mesenchymal Stem Cells/physiology ; Mice ; Octamer Transcription Factor-3/metabolism ; Octamer Transcription Factor-3/physiology ; Promoter Regions, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetik, Epigenetik und Umweltfaktoren der Lebenserwartung – Welche Rolle spielt Nature-versus-Nurture beim Altern?
Autorzy:
Bierhoff, HolgerAff1, Aff2, IDs0010302403873x_cor1
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Alternatywny tytuł:
Genetics, epigenetics, and environmental factors in life expectancy—What role does nature-versus-nurture play in aging?
Źródło:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. :1-7
Czasopismo naukowe
Szczegóły
Tytuł:
MiR-9-3 hypermethylation is associated with stages of diabetic retinopathy
Autorzy:
de Sousa, Bruno Rafael Virginio
Silva, Alexandre Sérgio
de Assis, Caroline Severo
Diniz, Tainá Gomes
Viturino, Marina Gonçalves Monteiro
de Queiroga Evangelista, Isabella Wanderley
Cavalcante-Silva, Luiz Henrique Agra
Keesen, Tatjana Souza Lima
de Oliveira, Naila Francis Paulo
Persuhn, Darlene CamatiAff1, Aff5, IDs40200024014119_cor10
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Źródło:
Journal of Diabetes & Metabolic Disorders. :1-10
Czasopismo naukowe
Szczegóły
Tytuł:
Valproate decreases transgenerationally blood pressure by affecting thyrotropin-releasing hormone promoter DNA methylation and gene expression in spontaneously hypertensive rat
Autorzy:
Landa, María S.Aff1, Aff2
Schuman, Mariano L.Aff1, Aff2
Aisicovich, MaiaAff1, Aff2
Peres Diaz, Ludmila S.Aff1, Aff2
Gironacci, Mariela M.
García, Silvia I.Aff1, Aff2, Aff5, IDs11010024050014_cor6
Pirola, Carlos J.Aff3, Aff4, IDs11010024050014_cor7
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Źródło:
Molecular and Cellular Biochemistry: An International Journal for Chemical Biology in Health and Disease. :1-13
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 36513

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