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Wyszukujesz frazę ""Epithelial-Mesenchymal Transition"" wg kryterium: Temat


Tytuł:
LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial-Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway.
Autorzy:
Hu C; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.; School of Life Sciences, Chongqing University, Chongqing 401331, China.
Zhou A; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.
Hu X; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.
Xiang Y; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.
Huang M; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.
Huang J; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Yang D; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing University of Arts and Sciences, Chongqing 402160, China.
Tang Y; College of Pharmacy (International Academy of Targeted Therapeutics and Innovation), Chongqing University of Arts and Sciences, Chongqing 402160, China.; National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing University of Arts and Sciences, Chongqing 402160, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 31; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Epithelial-Mesenchymal Transition*/drug effects
Epithelial-Mesenchymal Transition*/genetics
Erlotinib Hydrochloride*/pharmacology
Lamin Type A*/drug effects
Lamin Type A*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/metabolism ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
The intervention of epithelial-mesenchymal transition in homeostasis of human retinal pigment epithelial cells: a review.
Autorzy:
Gelat B; Department of Zoology, BMTC and Human Genetics, School of Sciences, Gujarat University, Ahmedabad, India.
Rathaur P; Department of Cell and Molecular Biology, Iladevi Cataract and IOL Research Centre, Ahmedabad, Gujarat, India.
Malaviya P; Department of Cell and Molecular Biology, Iladevi Cataract and IOL Research Centre, Ahmedabad, Gujarat, India.
Patel B; Department of Life Science, School of Sciences, Gujarat University, Ahmedabad, India.
Trivedi K; Department of Zoology, BMTC and Human Genetics, School of Sciences, Gujarat University, Ahmedabad, India.
Johar K; Department of Zoology, BMTC and Human Genetics, School of Sciences, Gujarat University, Ahmedabad, India.
Gelat R; Institute of Teaching and Research in Ayurveda (ITRA), Gujarat Ayurved University, Jamnagar, India.
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Źródło:
Journal of histotechnology [J Histotechnol] 2022 Dec; Vol. 45 (4), pp. 148-160. Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/physiology
Vitreoretinopathy, Proliferative*/metabolism
Humans ; Retinal Pigment Epithelium/metabolism ; Epithelial Cells/metabolism ; Homeostasis ; Retinal Pigments/metabolism
Czasopismo naukowe
Tytuł:
Alternative polyadenylation writer CSTF2 forms a positive loop with FGF2 to promote tubular epithelial-mesenchymal transition and renal fibrosis.
Autorzy:
Tan Y; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Zheng T; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Zhang R; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Chen S; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, Western Australia 6150, Australia.
Cheng Q; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Zhang J; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Wang R; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.
Chen M; Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address: .
Na N; Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Dec 01; Vol. 1868 (12), pp. 166541. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cleavage Stimulation Factor*/genetics
Cleavage Stimulation Factor*/metabolism
Epithelial-Mesenchymal Transition*
Fibroblast Growth Factor 2*/genetics
Fibroblast Growth Factor 2*/metabolism
Kidney Diseases*/genetics
3' Untranslated Regions ; Fibrosis ; Humans ; MicroRNAs/genetics ; Oligonucleotides, Antisense ; Polyadenylation ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells.
Autorzy:
Takano C; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.; Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan.
Horie M; Department of Molecular and Cellular Pathology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Taiko I; Department of Physiology, Nihon University School of Medicine, Tokyo, Japan.
Trinh QD; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Kanemaru K; Department of Physiology, Nihon University School of Medicine, Tokyo, Japan.
Komine-Aizawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Hayakawa S; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Miki T; Department of Physiology, Nihon University School of Medicine, Tokyo, Japan. .
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Źródło:
Stem cell reviews and reports [Stem Cell Rev Rep] 2022 Dec; Vol. 18 (8), pp. 3083-3091. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Placenta*/metabolism
Humans ; Female ; Pregnancy ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta/pharmacology ; Cell Differentiation/genetics ; Epithelial Cells
Czasopismo naukowe
Tytuł:
The antioxidative effects of empagliflozin on high glucose‑induced epithelial-mesenchymal transition in peritoneal mesothelial cells via the Nrf2/HO-1 signaling.
Autorzy:
Shi P; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Zhan Z; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Ye X; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Lu Y; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Song K; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Sheng F; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Shen H; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yin P; Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
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Źródło:
Renal failure [Ren Fail] 2022 Dec; Vol. 44 (1), pp. 1528-1542.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Heme Oxygenase-1*/metabolism
Animals ; Antioxidants/pharmacology ; Benzhydryl Compounds ; Dialysis Solutions/pharmacology ; GA-Binding Protein Transcription Factor ; Glucose/metabolism ; Glucosides ; Humans ; NF-E2-Related Factor 2/metabolism ; Rats ; Signal Transduction
Czasopismo naukowe
Tytuł:
TRIM46 upregulates Wnt/β-catenin signaling by inhibiting Axin1 to mediate hypoxia-induced epithelial-mesenchymal transition in HK2 cells.
Autorzy:
Liao L; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Duan L; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Guo Y; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Zhou B; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Xu Q; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Zhang C; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu W; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu W; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Liu Z; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Hu J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China.
Chen J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China. sea_.
Lu J; Department of Nephrology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, No.358 Datong Road in Pudong New District, Shanghai, 200137, China. .
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Źródło:
Molecular and cellular biochemistry [Mol Cell Biochem] 2022 Dec; Vol. 477 (12), pp. 2829-2839. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Kidney Diseases*/metabolism
Wnt Signaling Pathway*
Animals ; Humans ; Rats ; Axin Protein/genetics ; beta Catenin/metabolism ; Fibrosis ; Hypoxia
Czasopismo naukowe
Tytuł:
Blue light attenuates TGF-β2-induced epithelial-mesenchymal transition in human lens epithelial cells via autophagy impairment.
Autorzy:
Zhang D; Department of Ophthalmology, Shaoxing Central Hospital, Shaoxing, Zhejiang Province, China.
Zhu H; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Yu X; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Wang L; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Wen Y; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Zhang L; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Tong J; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China.
Shen Y; Department of Ophthalmology, the First Affiliated Hospital of Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, Zhejiang Province, China. .
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Źródło:
BMC ophthalmology [BMC Ophthalmol] 2022 Nov 28; Vol. 22 (1), pp. 456. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Transforming Growth Factor beta2*/pharmacology
Epithelial-Mesenchymal Transition*
Humans ; Epithelial Cells ; Autophagy ; Chloroquine ; Sirolimus
Czasopismo naukowe
Tytuł:
Mitochondrial Factor C20orf7 Facilitates the EMT-Mediated Cancer Cell Migration and the Proliferation of Colon Cancer In Vitro and In Vivo.
Autorzy:
Liu HH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Lee CH; School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Hsieh YC; Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.; Ph.D. Program in Biotechnology Research and Development, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Zheng JH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Liu YR; Joint Biobank, Office of Human Research, Taipei Medical University, Taipei 110, Taiwan.
Chang CH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Cho EC; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.; Master Program in Clinical Genomics and Proteomics, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.; Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 110, Taiwan.
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Źródło:
Genes [Genes (Basel)] 2022 Nov 14; Vol. 13 (11). Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Colonic Neoplasms*/drug therapy
Colonic Neoplasms*/genetics
Humans ; Mice ; Animals ; Cell Movement/genetics ; Mitochondria ; Fluorouracil/pharmacology ; Disease Models, Animal ; Cell Proliferation/genetics
Czasopismo naukowe
Tytuł:
Response of TGF-β isoforms in epithelial-mesenchymal transition of enamel epithelial cells.
Autorzy:
Miyakawa Y; Department of Pediatric Dentistry, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Chiba-Ohkuma R; Department of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Karakida T; Department of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Yamamoto R; Department of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Kobayashi S; Department of Pediatric Dentistry, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Yamakoshi Y; Department of Biochemistry and Molecular Biology, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
Asada Y; Department of Pediatric Dentistry, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan. Electronic address: .
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Źródło:
Archives of oral biology [Arch Oral Biol] 2022 Nov; Vol. 143, pp. 105540. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Transforming Growth Factor beta1*/metabolism
Transforming Growth Factor beta1*/pharmacology
Dental Enamel/metabolism ; Endoglin/metabolism ; Epithelial Cells/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Protein Isoforms/metabolism ; Receptors, Transforming Growth Factor beta/metabolism ; Transforming Growth Factors/metabolism ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Tytuł:
m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells.
Autorzy:
Suphakhong K; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
Terashima M; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
Wanna-Udom S; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
Takatsuka R; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
Ishimura A; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
Takino T; Division of Education for Global Standard, Institute of Liberal Arts and Science, Kanazawa University, Kanazawa, Ishikawa, Japan.
Suzuki T; Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102554. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Humans ; Transforming Growth Factor beta/metabolism ; Methylation ; RNA, Messenger/genetics ; Transcription Factor AP-1/metabolism ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Transforming Growth Factors/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
An Individualized EMT-Related Gene Signature to Predict Recurrence-Free Survival in Stage II/III Colorectal Cancer Patients.
Autorzy:
Zhang W; Division of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Zhang X; Division of Gastrointestinal Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Zhao D; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Hu M; Charité Universitätsmedizin Berlin, Berlin, Germany.
Ge X; Department of Endocrinology, The Second Affiliated Hospital of Nantong University and First People's Hospital of Nantong City, Jiangsu, China.
Xia L; Department of Surgery, The Fourth People's Hospital of Huai'an, Huai'an, China. .
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Źródło:
Digestive diseases and sciences [Dig Dis Sci] 2022 Nov; Vol. 67 (11), pp. 5116-5126. Date of Electronic Publication: 2022 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/surgery
Humans ; Gene Expression Profiling ; Retrospective Studies ; Neoplasm Recurrence, Local/genetics
Czasopismo naukowe
Tytuł:
Resveratrol inhibits TGF-β1-induced EMT in gastric cancer cells through Hippo-YAP signaling pathway.
Autorzy:
Deng L; General Department of Oncology, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, 330029, Jiangxi, People's Republic of China.
Zou J; Department of Abdominal Tumor Surgery, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, 330029, Jiangxi, People's Republic of China.
Su Y; General Department of Oncology, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, 330029, Jiangxi, People's Republic of China.
Wang M; General Department of Oncology, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, 330029, Jiangxi, People's Republic of China.
Zhao L; Department of Gastroenterology, Gaoxin Branch Of The First Affiliated Hospital Of Nanchang University, No. 7889 Changdong Ave, Gaoxin District, Nanchang, 330029, Jiangxi, People's Republic of China. .
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Źródło:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2022 Nov; Vol. 24 (11), pp. 2210-2221. Date of Electronic Publication: 2022 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Stomach Neoplasms*/metabolism
Animals ; Cadherins/metabolism ; Cell Line, Tumor ; Cell Movement ; Hippo Signaling Pathway ; Mice ; Protein Serine-Threonine Kinases ; RNA ; Resveratrol/pharmacology ; Transforming Growth Factor beta1/metabolism ; Vimentin/metabolism ; YAP-Signaling Proteins
Czasopismo naukowe
Tytuł:
Parecoxib expresses anti-metastasis effect through inhibition of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway in human colon cancer DLD-1 cell line.
Autorzy:
Wong CH; Department of Anesthesiology, Chang Gung Memorial Hospital at ChiaYi, Chia-Yi, Taiwan, ROC.
Chang WL; Department of Anesthesiology, Chang Gung Memorial Hospital at ChiaYi, Chia-Yi, Taiwan, ROC.
Lu FJ; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.
Liu YW; Department of Microbiology, Immunology and Biopharmaceuticals, College of Life Sciences, National Chiayi University, Chiayi City, Taiwan, ROC.
Peng JY; Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chia-Yi, Taiwan, ROC.
Chen CH; Department of Microbiology, Immunology and Biopharmaceuticals, College of Life Sciences, National Chiayi University, Chiayi City, Taiwan, ROC.
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Źródło:
Environmental toxicology [Environ Toxicol] 2022 Nov; Vol. 37 (11), pp. 2718-2727. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/pathology
Epithelial-Mesenchymal Transition*
Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal ; Cadherins/metabolism ; Cell Line ; Cell Line, Tumor ; Cell Movement ; Cyclooxygenase 2/metabolism ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; Isoxazoles ; Proto-Oncogene Proteins c-akt/metabolism ; Vimentin/metabolism ; Wnt Signaling Pathway ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Autorzy:
Deng R; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Lu X; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Hong C; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Cai R; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Wang P; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Xiong L; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Wang X; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Chen Q; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Department of Pathology,School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China.
Lin J; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China. jielin_.; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China. jielin_.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou, 510515, Guangdong, People's Republic of China. jielin_.; National Virtual & Reality Experimental Education Center for Medical Morphology, Southern Medical University, Guangzhou, 510515, Guangdong, People's Republic of China. jielin_.
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Oct 23; Vol. 20 (1), pp. 485. Date of Electronic Publication: 2022 Oct 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Carcinoma, Hepatocellular*/pathology
Epithelial-Mesenchymal Transition*/genetics
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Liver Neoplasms*/pathology
Humans ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Down-Regulation/genetics ; Gene Expression Regulation, Neoplastic ; Lipase/genetics ; Lipase/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Intercellular Communication Reveals Therapeutic Potential of Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer.
Autorzy:
Liu Y; Pharmacy Intravenous Admixture Services, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Fang Y; Department of Phase I Clinical Trial Ward, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Bao L; Pharmacy Intravenous Admixture Services, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Wu F; Department of Gastroenterology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Wang S; Pharmacy Intravenous Admixture Services, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Hao S; Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
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Źródło:
Biomolecules [Biomolecules] 2022 Oct 14; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Triple Negative Breast Neoplasms*/metabolism
Humans ; Ligands ; Cell Line, Tumor ; Cell Communication ; Forkhead Transcription Factors/genetics ; Tumor Necrosis Factors/genetics ; Tumor Necrosis Factors/metabolism ; Tumor Necrosis Factors/therapeutic use ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic ; Cell Proliferation/genetics ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
B7-H4 is a potential diagnostic and prognostic biomarker in colorectal cancer and correlates with the epithelial-mesenchymal transition.
Autorzy:
Yan X; Department of Clinical Laboratory, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, 166 North Qiutao Road, Hangzhou, Zhejiang Province, 310006, China.
Hong B; Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang Province, China.
Feng J; Department of Blood Transfusion, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang Province, China.
Jin Y; Department of Clinical Laboratory, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang Province, China.
Chen M; School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang Province, China.
Li F; Shanghai Upper Bio Tech Pharma Company Limited, Shanghai, 201201, China.
Qian Y; Department of Clinical Laboratory, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, 166 North Qiutao Road, Hangzhou, Zhejiang Province, 310006, China. .
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Źródło:
BMC cancer [BMC Cancer] 2022 Oct 10; Vol. 22 (1), pp. 1053. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Epithelial-Mesenchymal Transition*/genetics
Biomarkers, Tumor/metabolism ; Cadherins/metabolism ; Humans ; Prognosis ; RNA, Messenger ; Tumor Microenvironment ; Vimentin
Czasopismo naukowe
Tytuł:
Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial-Mesenchymal Transition Program.
Autorzy:
Foster DB; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Gu JM; Department of Pediatrics, Emory University, Atlanta, Georgia 30322, United States.
Kim EH; Cedars-Sinai Medical Center, Los Angeles, California 90048, United States.
Wolfson DW; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States.
O'Meally R; Proteomics Core Facility, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Cole RN; Proteomics Core Facility, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Cho HC; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
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Źródło:
Journal of proteome research [J Proteome Res] 2022 Oct 07; Vol. 21 (10), pp. 2277-2292. Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Transdifferentiation*
Epithelial-Mesenchymal Transition*/genetics
Myocytes, Cardiac*/metabolism
T-Box Domain Proteins*/genetics
T-Box Domain Proteins*/metabolism
Animals ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/genetics ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/metabolism ; Proteome/metabolism ; Proteomics ; Rats ; TRPM Cation Channels/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Ubiquitin-specific Protease 4 Attenuates Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells via Transforming Growth Factor Beta Receptor Type I.
Autorzy:
Pu JY; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhang Y; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Wang LX; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Wang J; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhou JH; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. .
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Źródło:
Current medical science [Curr Med Sci] 2022 Oct; Vol. 42 (5), pp. 1000-1006. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Kidney Diseases*/genetics
Animals ; Rats ; Actins/genetics ; Actins/metabolism ; Cadherins/genetics ; Cadherins/metabolism ; Epithelial Cells/metabolism ; Fibrosis ; RNA, Small Interfering/genetics ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism ; Ubiquitin-Specific Proteases/genetics ; Ubiquitin-Specific Proteases/metabolism
Czasopismo naukowe
Tytuł:
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
Autorzy:
Gao F; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China. Electronic address: .
Wang L; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China.
Wu B; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China.
Ou Q; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China.
Tian H; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China.
Xu J; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China.
Jin C; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China.
Zhang J; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Pharmacology, Tongji University School of Medicine, Shanghai, 200092, China.
Wang J; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China.
Lu L; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, 200092, China. Electronic address: .
Xu GT; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, Tongji University School of Medicine, 389 Xincun Road Shanghai, 200065, China; Department of Pharmacology, Tongji University School of Medicine, Shanghai, 200092, China. Electronic address: .
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Źródło:
Experimental eye research [Exp Eye Res] 2022 Oct; Vol. 223, pp. 109207. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*
Macular Degeneration*/metabolism
Cellular Senescence ; Culture Media, Conditioned/pharmacology ; Dasatinib/pharmacology ; Epithelial Cells/metabolism ; Humans ; Hydrogen Peroxide/metabolism ; Quercetin/pharmacology ; Retinal Pigment Epithelium/metabolism ; Retinal Pigments/metabolism ; Retinal Pigments/pharmacology ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł:
Influence of sphingomyelin metabolism during epithelial-mesenchymal transition associated with aging in the renal papilla.
Autorzy:
Brandán YR; Instituto de Investigaciones en Ciencias de la Salud Humana (IICSHUM), Universidad Nacional de La Rioja, La Rioja, Argentina.
Favale NO; Facultad de Farmacia y Bioquímica, Cátedra de Biología Celular y Molecular, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química y Fisicoquímica Biológicas, CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina.
Pescio LG; Facultad de Farmacia y Bioquímica, Cátedra de Biología Celular y Molecular, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química y Fisicoquímica Biológicas, CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina.
Santacreu BJ; Facultad de Farmacia y Bioquímica, Cátedra de Biología Celular y Molecular, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química y Fisicoquímica Biológicas, CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina.
Guaytima EDV; Instituto de Investigaciones en Ciencias de la Salud Humana (IICSHUM), Universidad Nacional de La Rioja, La Rioja, Argentina.
Sterin-Speziale NB; Laboratorio Nacional de Investigación y Servicios de Péptidos y Proteínas - Espectrometría de Masa (LANAIS PROEM), Instituto de Química y Fisicoquímica Biológicas, CONICET - Universidad de Buenos Aires, Buenos Aires, Argentina.
Márquez MG; Instituto de Investigaciones en Ciencias de la Salud Humana (IICSHUM), Universidad Nacional de La Rioja, La Rioja, Argentina.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2022 Oct; Vol. 237 (10), pp. 3883-3899. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*
Kidney Diseases*
Animals ; Epithelial Cells/metabolism ; Fibrosis ; Kidney Medulla/metabolism ; Rats ; Sphingomyelin Phosphodiesterase/genetics ; Sphingomyelins/metabolism
Czasopismo naukowe

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