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Wyszukujesz frazę ""Epithelial-Mesenchymal Transition"" wg kryterium: Temat


Tytuł:
Pericardial delta like non-canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition.
Autorzy:
Jensen CH; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.
Johnsen RH; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.
Eskildsen T; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Baun C; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Ellman DG; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.
Fang S; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.
Bak ST; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.
Hvidsten S; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Larsen LA; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Rosager AM; Department of Clinical Pathology, Sydvestjysk Hospital, Esbjerg, Denmark.
Riber LP; Clinical Institute, University of Southern Denmark, Odense, Denmark.; Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark.
Schneider M; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
De Mey J; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Thomassen M; Clinical Institute, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Burton M; Clinical Institute, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Uchida S; Center for RNA Medicine, Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.
Laborda J; Department of Inorganic and Organic Chemistry and Biochemistry, University of Castilla-La Mancha Medical School, Albacete, Spain.
Andersen DC; Andersen Group, Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.; Clinical Institute, University of Southern Denmark, Odense, Denmark.; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1565.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*/genetics
Myocardial Infarction*/genetics
Adult ; Animals ; Humans ; Mice ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Cicatrix/metabolism ; Cicatrix/pathology ; Fibrosis ; Ligands ; Mice, Transgenic ; Pericardium/metabolism ; Thorax/pathology
Czasopismo naukowe
Tytuł:
Extracellular vesicles from retinal pigment epithelial cells expressing R345W-Fibulin-3 induce epithelial-mesenchymal transition in recipient cells.
Autorzy:
Zhou M; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Zhao Y; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Weber SR; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Gates C; Bioinformatics Core, Biomedical Research Core Facilities, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Carruthers NJ; Bioinformatics Core, Biomedical Research Core Facilities, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Chen H; Microscopy Imaging Core Facility, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Liu X; Department of Pediatrics, Division of Hematology and Oncology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Wang HG; Department of Pediatrics, Division of Hematology and Oncology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Ford M; MS Bioworks LLC, Ann Arbor, Michigan, USA.
Swulius MT; Department of Biochemistry and Molecular Biology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Barber AJ; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Grillo SL; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
Sundstrom JM; Department of Ophthalmology, Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2023 Oct; Vol. 12 (10), pp. e12373.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*
Extracellular Vesicles*/metabolism
Chromatography, Liquid ; Hedgehog Proteins/metabolism ; Tandem Mass Spectrometry ; Epithelial Cells/metabolism ; Transforming Growth Factor beta/metabolism ; Luciferases/metabolism ; Retinal Pigments/metabolism
Czasopismo naukowe
Tytuł:
PD1 exhausted T cell increase immunotherapy resistance and tumour progression by promoting epithelial-mesenchymal transition in bladder cancer.
Autorzy:
Wu C; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Duan L; School of Life Sciences, Zhengzhou University, Zhengzhou, P. R. China.
Li H; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Liu X; School of Medicine, Southern University of Science and Technology, Shenzhen, P. R. China.; Shenzhen Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, P. R. China.
Cai T; Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Yang Y; School of Geography and Environmental Sciences, Northwest Normal University, Lanzhou, P. R. China.
Yin Y; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Chang W; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Zhong L; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Zhang L; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Department of Clinical Laboratory, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China.
Cheng Y; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Qin H; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Wen Z; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Department of Thoracic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Wang H; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Mai S; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Jun; Vol. 13 (6), pp. e1303.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*
Urinary Bladder Neoplasms*/therapy
Humans ; T-Lymphocytes ; Neoplasm Recurrence, Local ; CD4-Positive T-Lymphocytes ; Tumor Microenvironment ; Methyltransferases
Czasopismo naukowe
Tytuł:
PROM2 overexpression induces metastatic potential through epithelial-to-mesenchymal transition and ferroptosis resistance in human cancers.
Autorzy:
Paris J; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.
Wilhelm C; Laboratoire Physico Chimie Curie, Institut Curie, CNRS, PSL Research University, Paris, France.
Lebbé C; Université Paris Cité, INSERM, Paris, France.; APHP, Dermatolo-Oncology, Hôpital Saint Louis, Paris, France.
Elmallah M; Inserm U1327 ISCHEMIA, Université de Tours, Faculté de Médecine, Tours, France.
Pamoukdjian F; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.; APHP, Hôpital Avicenne, Médecine Gériatrique, Bobigny, France.; Université Sorbonne Paris Nord, Villetaneuse, France.
Héraud A; Inserm U1327 ISCHEMIA, Université de Tours, Faculté de Médecine, Tours, France.
Gapihan G; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.
Walle AV; Laboratoire Physico Chimie Curie, Institut Curie, CNRS, PSL Research University, Paris, France.
Tran VN; School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
Hamdan D; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.; Hôpital La Porte Verte, Cancérologie, Versailles, France.
Allayous C; Université Paris Cité, INSERM, Paris, France.; APHP, Dermatolo-Oncology, Hôpital Saint Louis, Paris, France.
Battistella M; Université Paris Cité, INSERM, Paris, France.; Pathology Department, APHP, Hôpital Saint Louis, Paris, France.
Van Glabeke E; Fédération d'Urologie de Seine-Saint-Denis, CHI Robert Ballangé, Aulnay-sous-Bois, France.
Lim KW; School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
Leboeuf C; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.
Roger S; Inserm U1327 ISCHEMIA, Université de Tours, Faculté de Médecine, Tours, France.
Falgarone G; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.; APHP, Hôpital Avicenne, Médecine Gériatrique, Bobigny, France.; APHP, Hôpital Avicenne, Unité de Médecine Ambulatoire (UMA), Bobigny, France.
Phan AT; Université Sorbonne Paris Nord, Villetaneuse, France.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore.
Bousquet G; Université Paris Cité, INSERM, UMR_S942 MASCOT, Paris, France.; APHP, Hôpital Avicenne, Médecine Gériatrique, Bobigny, France.; APHP, Hôpital Avicenne, Oncologie médical, Bobigny, France.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1632.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Melanoma*
Ferroptosis*/genetics
Humans ; Animals ; Mice ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition/genetics ; Membrane Glycoproteins
Czasopismo naukowe
Tytuł:
Dynamic regulation of tumour progression by phenotype-switching drivers.
Autorzy:
Vock L; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
Gschwendtner A; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
Eckel O; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
Mirea MA; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
Hengstschläger M; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
Mikula M; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jul; Vol. 12 (7), pp. e840.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Epithelial-Mesenchymal Transition*
Neoplastic Processes*
Humans ; Phenotype
Czasopismo naukowe
Tytuł:
Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles.
Autorzy:
Bhome R; Cancer Sciences Unit, University of Southampton, Southampton, UK.; University Surgery, University of Southampton, Southampton, UK.
Emaduddin M; Cancer Sciences Unit, University of Southampton, Southampton, UK.
James V; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
House LM; Cancer Sciences Unit, University of Southampton, Southampton, UK.
Thirdborough SM; Cancer Sciences Unit, University of Southampton, Southampton, UK.
Mellone M; Cancer Sciences Unit, University of Southampton, Southampton, UK.
Tulkens J; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Primrose JN; University Surgery, University of Southampton, Southampton, UK.
Thomas GJ; Cancer Sciences Unit, University of Southampton, Southampton, UK.
De Wever O; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Mirnezami AH; Cancer Sciences Unit, University of Southampton, Southampton, UK.; University Surgery, University of Southampton, Southampton, UK.
Sayan AE; Cancer Sciences Unit, University of Southampton, Southampton, UK.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2022 May; Vol. 11 (5), pp. e12226.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Epithelial-Mesenchymal Transition*/genetics
Extracellular Vesicles*/genetics
Extracellular Vesicles*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Fibroblasts/metabolism ; Humans ; Mice ; Phenotype
Czasopismo naukowe
Tytuł:
Upregulation of LINC00501 by H3K27 acetylation facilitates gastric cancer metastasis through activating epithelial-mesenchymal transition and angiogenesis.
Autorzy:
Dou R; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Han L; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Yang C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Fang Y; Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China.
Zheng J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Liang C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Song J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Wei C; Department of Internal Medicine, Affiliated Tumor Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Huang G; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Zhong P; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Liu K; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Peng Q; Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Peng C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Xiong B; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
Wang S; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, Hubei, China.; Hubei Cancer Clinical Study Center, Wuhan, Hubei, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Oct; Vol. 13 (10), pp. e1432.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stomach Neoplasms*/pathology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Humans ; Up-Regulation/genetics ; Epithelial-Mesenchymal Transition/genetics ; Acetylation ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Hsa_circ_0057105 modulates a balance of epithelial-mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma.
Autorzy:
Cen J; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Liang Y; Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Feng Z; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Chen X; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Chen J; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Wang Y; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Zhu J; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Xu Q; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Shu G; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Zheng W; Department of Emergency, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Liang H; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, People's Republic of China.
Wang Z; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, People's Republic of China.
Deng Q; Department of Urology, Affiliated Longhua People's Hospital, Southern Medical University, Shenzhen, People's Republic of China.
Cao J; Department of Urology, Jiangmen Central Hospital, Jiangmen, People's Republic of China.
Luo J; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.; Institute of Precision Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Jin X; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Huang Y; Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.; Department of Emergency, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1339.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Renal Cell*/metabolism
Ferroptosis*/genetics
MicroRNAs*/genetics
Kidney Neoplasms*/metabolism
Animals ; RNA, Circular/genetics ; RNA, Circular/metabolism ; Epithelial-Mesenchymal Transition/genetics ; In Situ Hybridization, Fluorescence
Czasopismo naukowe
Tytuł:
Sphingosine-1-phosphate/TGF-β axis drives epithelial mesenchymal transition in asthma-like disease.
Autorzy:
Riemma MA; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Cerqua I; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Romano B; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Irollo E; Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Bertolino A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Camerlingo R; RCCS INT Cellular Biology and Bioterapy- Research Department, National Cancer Institute G. Pascale Foundation, Naples, Italy.
Granato E; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Rea G; IRCCS INT Microenvironment Molecular Targets, National Cancer Institute G. Pascale Foundation, Naples, Italy.
Scala S; IRCCS INT Microenvironment Molecular Targets, National Cancer Institute G. Pascale Foundation, Naples, Italy.
Terlizzi M; Department of Pharmacy (DIFARMA), University of Salerno, Salerno, Italy.
Spaziano G; Department of Experimental Medicine L. Donatelli, Section of Pharmacology, School of Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Sorrentino R; Department of Pharmacy (DIFARMA), University of Salerno, Salerno, Italy.
D'Agostino B; Department of Experimental Medicine L. Donatelli, Section of Pharmacology, School of Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Roviezzo F; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Cirino G; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Naples, Italy.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2022 Apr; Vol. 179 (8), pp. 1753-1768. Date of Electronic Publication: 2022 Jan 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Asthma*/metabolism
Asthma*/pathology
Epithelial-Mesenchymal Transition*
Sphingosine*/analogs & derivatives
Sphingosine*/pharmacology
Transforming Growth Factor beta*/metabolism
Airway Remodeling ; Animals ; Epithelial Cells ; Lysophospholipids ; Mice ; Mice, Inbred BALB C ; Ovalbumin ; Transforming Growth Factor beta1
Czasopismo naukowe
Tytuł:
EMT-cancer cells-derived exosomal miR-27b-3p promotes circulating tumour cells-mediated metastasis by modulating vascular permeability in colorectal cancer.
Autorzy:
Dou R; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Liu K; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Yang C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Zheng J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Shi D; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Lin X; Department of Breast Surgery and General Surgery, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Wei C; Department of Internal Medicine, Affiliated Tumor Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Zhang C; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Fang Y; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Huang S; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Song J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Wang S; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Xiong B; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Department of Gastric and Colorectal Surgical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Dec; Vol. 11 (12), pp. e595.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Capillary Permeability/*physiology
Colorectal Neoplasms/*physiopathology
Epithelial-Mesenchymal Transition/*genetics
Aged ; Cell Movement/genetics ; Cell Proliferation/genetics ; Colorectal Neoplasms/complications ; Colorectal Neoplasms/genetics ; Epithelial-Mesenchymal Transition/physiology ; Female ; Humans ; Male ; MicroRNAs/analysis ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/physiopathology ; Neoplastic Cells, Circulating
Czasopismo naukowe
Tytuł:
Regulatory roles of osteopontin in human lung cancer cell epithelial-to-mesenchymal transitions and responses.
Autorzy:
Shi L; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Hou J; Institute for Clinical Science, Shanghai, China.; Shanghai Institute of Clinical Bioinformatics, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Jinshan Hospital Centre for Tumor Diagnosis and Therapy, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Wang L; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Fu H; Institute for Clinical Science, Shanghai, China.; Shanghai Institute of Clinical Bioinformatics, Shanghai, China.; Jinshan Hospital Centre for Tumor Diagnosis and Therapy, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Zhang Y; Institute for Clinical Science, Shanghai, China.; Shanghai Institute of Clinical Bioinformatics, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Jinshan Hospital Centre for Tumor Diagnosis and Therapy, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Song Y; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
Wang X; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai, China.; Institute for Clinical Science, Shanghai, China.; Shanghai Institute of Clinical Bioinformatics, Shanghai, China.; Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai, China.; Jinshan Hospital Centre for Tumor Diagnosis and Therapy, Shanghai, China.; Fudan University Shanghai Medical College, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Jul; Vol. 11 (7), pp. e486.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial-Mesenchymal Transition*/drug effects
Carcinoma, Non-Small-Cell Lung/*pathology
Lung Neoplasms/*pathology
Osteopontin/*metabolism
Animals ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Line, Tumor ; Female ; Humans ; Lung Neoplasms/metabolism ; Lymphatic Metastasis ; Male ; Mice ; Mice, Nude ; Middle Aged ; Osteopontin/antagonists & inhibitors ; Osteopontin/genetics ; Phosphatidylinositol 3-Kinases/chemistry ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoinositide-3 Kinase Inhibitors/pharmacology ; Prognosis ; RNA Interference ; RNA, Small Interfering/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł:
Synergistic activation of genes promoting invasiveness by dual deprivation in oxygen and nutrients.
Autorzy:
Jehanno C; University of Rennes, Inserm, EHESP, Irset UMR 1085, Rennes, France.; Department of Biomedicine, University of Basel, Basel, Switzerland.
Le Page Y; University of Rennes, Inserm, EHESP, Irset UMR 1085, Rennes, France.
Flouriot G; University of Rennes, Inserm, EHESP, Irset UMR 1085, Rennes, France.
Le Goff P; University of Rennes, Inserm, EHESP, Irset UMR 1085, Rennes, France.
Michel D; University of Rennes, Inserm, EHESP, Irset UMR 1085, Rennes, France.
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Źródło:
International journal of experimental pathology [Int J Exp Pathol] 2023 Apr; Vol. 104 (2), pp. 64-75. Date of Electronic Publication: 2023 Jan 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxygen*
Signal Transduction*
Humans ; MCF-7 Cells ; Epithelial-Mesenchymal Transition/physiology ; Neoplasm Invasiveness ; Cell Line, Tumor ; Cell Movement ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
Identification of BGN and THBS2 as metastasis-specific biomarkers and poor survival key regulators in human colon cancer by integrated analysis.
Autorzy:
He Z; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.; University of Chinese Academy of Sciences, Beijing, China.
Lin J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.; University of Chinese Academy of Sciences, Beijing, China.
Chen C; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.; University of Chinese Academy of Sciences, Beijing, China.
Chen Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.; University of Chinese Academy of Sciences, Beijing, China.
Yang S; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.; School of life Science, Yunnan University, Kunming, China.
Cai X; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
He Y; School of Chemical Science and Technology, Yunnan University, Kunming, China.
Liu S; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Nov; Vol. 12 (11), pp. e973.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colonic Neoplasms*/diagnosis
Colonic Neoplasms*/genetics
Colonic Neoplasms*/pathology
Humans ; Biglycan/metabolism ; Biglycan/pharmacology ; Biomarkers ; Cell Movement/genetics ; Epithelial-Mesenchymal Transition/genetics ; Prognosis
Czasopismo naukowe
Tytuł:
Function of cAMP scaffolds in obstructive lung disease: Focus on epithelial-to-mesenchymal transition and oxidative stress.
Autorzy:
Zuo H; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Cattani-Cavalieri I; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Valença SS; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Musheshe N; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.
Schmidt M; Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2019 Jul; Vol. 176 (14), pp. 2402-2415. Date of Electronic Publication: 2019 Mar 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Epithelial-Mesenchymal Transition*
Oxidative Stress*
Cyclic AMP/*metabolism
Pulmonary Disease, Chronic Obstructive/*metabolism
Animals ; Humans
Czasopismo naukowe
Tytuł:
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells.
Autorzy:
Dalhat MH; Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia.; Centre for Artificial Intelligence in Precision Medicines, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed MRS; Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia.; Centre for Artificial Intelligence in Precision Medicines, King Abdulaziz University, Jeddah, Saudi Arabia.
Alkhatabi HA; Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Rehan M; King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Saudi Arabia.; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmad A; Translational Research Institute, Hamad Medical Corporation, Doha, Qatar.
Choudhry H; Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia.; Centre for Artificial Intelligence in Precision Medicines, King Abdulaziz University, Jeddah, Saudi Arabia.
Khan MI; Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia.; Centre for Artificial Intelligence in Precision Medicines, King Abdulaziz University, Jeddah, Saudi Arabia.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Sep; Vol. 12 (9), pp. e1045.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytidine*/analysis
Cytidine*/genetics
Cytidine*/metabolism
Neoplasms*/genetics
Acetyltransferases ; Cholesterol ; Epithelial-Mesenchymal Transition ; Fatty Acids/genetics ; Palmitates ; RNA/chemistry ; Transferases ; Triglycerides
Czasopismo naukowe
Tytuł:
MiR-192-5p/RB1/NF-κBp65 signaling axis promotes IL-10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment.
Autorzy:
Song J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Lin Z; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Liu Q; Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.; Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China.
Huang S; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Han L; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Fang Y; Department of obstetrics and gynecology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Zhong P; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Dou R; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Xiang Z; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Zheng J; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Zhang X; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Wang S; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
Xiong B; Department of Gastrointestinal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.; Hubei Key Laboratory of Tumour Biological Behaviours, Wuhan, China.; Hubei Cancer Clinical Study Center, Wuhan, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Aug; Vol. 12 (8), pp. e992.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Stomach Neoplasms*/genetics
Stomach Neoplasms*/metabolism
Stomach Neoplasms*/pathology
Cell Differentiation/genetics ; Cell Proliferation ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism ; T-Lymphocytes, Regulatory/metabolism ; T-Lymphocytes, Regulatory/pathology ; Tumor Microenvironment/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł:
Transcriptional profiling of single tumour cells from pleural effusions reveals heterogeneity of epithelial to mesenchymal transition and extra-cellular matrix marker expression.
Autorzy:
Sen M; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hausler RM; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dulmage K; Life Science Innovation, BD Technologies and Innovations, Durham, North Carolina, USA.
Black TA; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Murphy W; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Pletcher CH Jr; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Wang L; Life Science Innovation, BD Technologies and Innovations, Durham, North Carolina, USA.
Chen C; Life Science Innovation, BD Technologies and Innovations, Durham, North Carolina, USA.
Yee SS; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bornheimer SJ; BD Biosciences, San Jose, California, USA.
Maxwell KN; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Stanger BZ; Department of Medicine, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Moore JS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Thompson JC; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Thoracic Oncology Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Carpenter EL; Department of Medicine, Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jul; Vol. 12 (7), pp. e888.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Pleural Effusion*
Pleural Effusion, Malignant*/genetics
Pleural Effusion, Malignant*/metabolism
Pleural Effusion, Malignant*/pathology
Epithelial-Mesenchymal Transition/genetics ; Humans
Raport
Tytuł:
High level of FHL2 exacerbates the outcome of non-small cell lung cancer (NSCLC) patients and the malignant phenotype in NSCLC cells.
Autorzy:
Li N; Department of Central Laboratory, Shenyang Tenth People's Hospital, Shenyang Chest Hospital, Liaoning, China.
Xu L; Department of Interventional Pulmonary Diseases, Anhui Chest Hospital, Hefei, China.
Zhang J; Department of Cardiothoracic Surgery, The Frist People's Hospital of Changde City, Changde, China.
Liu Y; Department of Thoracic Surgery, Shenyang Tenth People's Hospital, Shenyang Chest Hospital, Liaoning, China.
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Źródło:
International journal of experimental pathology [Int J Exp Pathol] 2022 Jun; Vol. 103 (3), pp. 90-101. Date of Electronic Publication: 2022 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
LIM-Homeodomain Proteins*/genetics
LIM-Homeodomain Proteins*/metabolism
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Muscle Proteins*/genetics
Muscle Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Animals ; Cadherins/genetics ; Cadherins/metabolism ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 9/genetics ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Nude ; Phenotype
Czasopismo naukowe
Tytuł:
Circ_0021087 acts as a miR-184 sponge and represses gastric cancer progression by adsorbing miR-184 and elevating FOSB expression.
Autorzy:
Yu Y; School of Basic Medicine, Zhengzhou University, Zhengzhou City, China.
Li H; Department of Radiology, Zhumadian Central Hospital Affiliated to Huanghuai University, Zhumadian City, China.
Wu C; Department of Oncology, Zhumadian Central Hospital Affiliated to Huanghuai University, Zhumadian City, China.
Li J; Department of Obstetrics and Gynecology, Zhumadian Central Hospital Affiliated to Huanghuai University, Zhumadian City, China.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2021 Nov; Vol. 51 (11), pp. e13605. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma/*genetics
DNA-Binding Proteins/*genetics
LIM Domain Proteins/*genetics
MicroRNAs/*metabolism
Proto-Oncogene Proteins c-fos/*genetics
RNA, Circular/*metabolism
RNA, Messenger/*metabolism
Stomach Neoplasms/*genetics
Transcription Factors/*genetics
Adenocarcinoma/metabolism ; Adenocarcinoma/pathology ; Animals ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; DNA-Binding Proteins/metabolism ; Disease Progression ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; LIM Domain Proteins/metabolism ; Mice ; Neoplasm Transplantation ; Proto-Oncogene Proteins c-fos/metabolism ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake.
Autorzy:
Wang T; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Wang X; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin, China.
Wang H; Department of Breast & Thyroid Surgery, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, The Second Chengdu Hospital Affiliated to Chongqing Medical University, Chengdu, Sichuan, China.
Li L; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Zhang C; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Xiang R; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Tan X; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Li Z; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
Jiang C; Department of Thoracic Surgery, Tianjin Union Medical Center, Tianjin, China.
Zheng L; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiao L; State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, College of Chemistry, Nankai University, Tianjin, China.
Yue S; School of Medicine, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2021 Nov; Vol. 10 (13), pp. e12167.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms/*metabolism
Cell Communication/*genetics
Extracellular Vesicles/*metabolism
Liver/*metabolism
Lung/*metabolism
Signal Transduction/*genetics
Spleen/*metabolism
Tetraspanins/*metabolism
Animals ; Breast Neoplasms/pathology ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Cell Line, Tumor ; Cell Movement/genetics ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Knockdown Techniques/methods ; Heterografts ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Tetraspanin 24/metabolism ; Tetraspanins/genetics ; Transfection
Czasopismo naukowe

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