- Tytuł :
- The crosstalk between p38 and Akt signaling pathways orchestrates EMT by regulating SATB2 expression in NSCLC cells
- Autorzy :
- Temat :
-
Blotting, Western
Carcinoma, Non-Small-Cell Lung/metabolism/*pathology
Cell Line, TumorEpithelial -Mesenchymal Transition /*physiology
Gene Expression Regulation, Neoplastic/physiology
Gene Knockdown Techniques
Humans
Lung Neoplasms/metabolism/*pathology
MAP Kinase Signaling System/physiology
Matrix Attachment Region Binding Proteins/*biosynthesis
PTEN Phosphohydrolase/metabolism
Proto-Oncogene Proteins c-akt/metabolism
Receptor Cross-Talk/*physiology
Signal Transduction/physiology
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
General Medicine
Tensin
Signal transduction
Protein kinase B
Lung cancer
medicine.disease
medicineEpithelial –mesenchymal transition
PTEN
biology.protein
biology
Regulation of gene expression
Chemistry
Cancer research
Cancer cell
Aktepithelial –mesenchymal transition
non-small-cell lung cancer
p38
SATB2
mitogen activated protein kinase p38
phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase
protein kinase B
transcription factor
transcription factor SATB2
unclassified drug
matrix attachment region binding protein
PTEN protein, human
SATB2 protein, human
Akt signaling
Article
AT rich sequence
controlled study
enzyme activation
epigeneticsepithelial mesenchymal transition
gene silencing
lung metastasis
lung non-small cell carcinoma cell line
molecular dynamics
molecular interaction
non small cell lung cancer
priority journal
protein expression
upregulation
biosynthesis
gene expression regulation
human
lung tumor
MAPK signaling
metabolism
pathologyphysiology
signal transduction
tumor cell line
Western blotting
Carcinoma, Non-Small-Cell LungEpithelial -Mesenchymal Transition
Gene Expression Regulation, Neoplastic
Lung Neoplasms
MAP Kinase Signaling System
Matrix Attachment Region Binding Proteins
Proto-Oncogene Proteins c-akt
PTEN Phosphohydrolase
Receptor Cross-Talk
Transcription Factors - Źródło :
-
Tumor Biology, Vol 39 (2017)
Crossref - Opis pliku :
- application/pdf
- Dostępność :
- https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f33e1adc87416c20f7dadf7fd557354