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Tytuł :
Induced Pluripotent Stem Cell Modeling of Best Disease and Autosomal Recessive Bestrophinopathy.
Autorzy :
Lee JH; Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
Oh JO; Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
Lee CS; Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea. .
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Źródło :
Yonsei medical journal [Yonsei Med J] 2020 Sep; Vol. 61 (9), pp. 816-825.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Yonsei University Country of Publication: Korea (South) NLM ID: 0414003 Publication Model: Print Cited Medium: Internet ISSN: 1976-2437 (Electronic) Linking ISSN: 05135796 NLM ISO Abbreviation: Yonsei Med. J. Subsets: MEDLINE
MeSH Terms :
Induced Pluripotent Stem Cells*/cytology
Induced Pluripotent Stem Cells*/metabolism
Retinal Pigment Epithelium*/metabolism
Retinal Pigment Epithelium*/physiopathology
Bestrophins/*genetics
Eye Diseases, Hereditary/*genetics
Retinal Diseases/*genetics
Vitelliform Macular Dystrophy/*genetics
Vitelliform Macular Dystrophy/*physiopathology
Cell Differentiation ; Chloride Channels/genetics ; Chloride Channels/metabolism ; Eye Diseases, Hereditary/diagnosis ; Eye Diseases, Hereditary/metabolism ; Eye Diseases, Hereditary/pathology ; Gene Expression ; Humans ; Retinal Diseases/diagnosis ; Vision Disorders ; Visual Acuity ; Vitelliform Macular Dystrophy/metabolism
SCR Disease Name :
Bestrophinopathy
Czasopismo naukowe
Tytuł :
Monounsaturated oleic acid modulates autophagy flux and upregulates angiogenic factor production in human retinal pigment epithelial ARPE-19 cells.
Autorzy :
Chang YC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Ophthalmology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Lin CW; Department of Ophthalmology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chang YS; Department of Ophthalmology, Chi Mei Medical Center, Tainan, Taiwan; Graduate Institute of Medical Science, College of Health Science, Gang Jung Christian University, Tainan, Taiwan.
Chen PH; Department of Medical Research, E-Da Hospital, Kaohsiung, Taiwan.
Li CY; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Wu WC; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
Kao YH; Department of Medical Research, E-Da Hospital, Kaohsiung, Taiwan. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118391. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
MeSH Terms :
Autophagy*
Angiogenesis Inducing Agents/*metabolism
Oleic Acid/*metabolism
Retinal Pigment Epithelium/*metabolism
Blotting, Western ; Cell Movement ; Cell Proliferation ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Humans ; MAP Kinase Signaling System ; Palmitic Acid/metabolism ; Retinal Pigment Epithelium/cytology ; Reverse Transcriptase Polymerase Chain Reaction ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Long Noncoding RNA MEG3 Inhibits Apoptosis of Retinal Pigment Epithelium Cells Induced by High Glucose via the miR-93/Nrf2 Axis.
Autorzy :
Luo R; Department of Ophthalmology, Provincial People's Hospital Affiliated to Nanchang University, Nanchang, P.R. China.
Jin H; Department of Ophthalmology, Provincial People's Hospital Affiliated to Nanchang University, Nanchang, P.R. China.
Li L; Department of Ophthalmology, Provincial People's Hospital Affiliated to Nanchang University, Nanchang, P.R. China.
Hu YX; Department of Ophthalmology, Provincial People's Hospital Affiliated to Nanchang University, Nanchang, P.R. China.
Xiao F; Department of Ophthalmology, Provincial People's Hospital Affiliated to Nanchang University, Nanchang, P.R. China. Electronic address: .
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Źródło :
The American journal of pathology [Am J Pathol] 2020 Sep; Vol. 190 (9), pp. 1813-1822. Date of Electronic Publication: 2020 May 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am. J. Pathol. Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Diabetic Retinopathy/*metabolism
MicroRNAs/*metabolism
NF-E2-Related Factor 2/*metabolism
RNA, Long Noncoding/*metabolism
Retinal Pigment Epithelium/*pathology
Apoptosis/physiology ; Cell Line ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Diabetic Retinopathy/pathology ; Gene Expression Regulation ; Humans ; Retinal Pigment Epithelium/metabolism ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Corneal Epithelial Thickness Measured Using Anterior Segment Optical Coherence Tomography as a Diagnostic Parameter for Limbal Stem Cell Deficiency.
Autorzy :
Liang Q; Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, China.
Le Q; Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Cordova DW; Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Tseng CH; Department of Medicine, Statistic Core-General Internal Medicine and Health Service Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Deng SX; Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA. Electronic address: .
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Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2020 Aug; Vol. 216, pp. 132-139. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Corneal Diseases/*diagnosis
Epithelium, Corneal/*pathology
Limbus Corneae/*pathology
Stem Cells/*pathology
Adult ; Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Epithelium, Corneal/diagnostic imaging ; Female ; Fourier Analysis ; Humans ; Limbus Corneae/diagnostic imaging ; Male ; Microscopy, Confocal ; Middle Aged ; Organ Size ; Prospective Studies ; Tomography, Optical Coherence ; Young Adult
Czasopismo naukowe
Tytuł :
Annexin A8 regulates Wnt signaling to maintain the phenotypic plasticity of retinal pigment epithelial cells.
Autorzy :
Lueck K; UCL Institute of Ophthalmology, 11-43 Bath Street, EC1V 9EL, London, United Kingdom.
Carr AF; UCL Institute of Ophthalmology, 11-43 Bath Street, EC1V 9EL, London, United Kingdom.
Yu L; PAREXEL International, The Quays, 101-105 Oxford Road UB8 1LZ, Uxbridge, United Kingdom.
Greenwood J; UCL Institute of Ophthalmology, 11-43 Bath Street, EC1V 9EL, London, United Kingdom.
Moss SE; UCL Institute of Ophthalmology, 11-43 Bath Street, EC1V 9EL, London, United Kingdom. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jan 27; Vol. 10 (1), pp. 1256. Date of Electronic Publication: 2020 Jan 27.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
MeSH Terms :
Annexins/*metabolism
Retinal Pigment Epithelium/*metabolism
Wnt Signaling Pathway/*physiology
Adaptation, Physiological ; Annexins/physiology ; Cell Line ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Epithelium/metabolism ; Gene Expression/genetics ; Gene Expression Profiling/methods ; Gene Expression Regulation, Developmental/genetics ; Humans ; Phenotype ; Primary Cell Culture ; Retinal Pigment Epithelium/physiology ; Signal Transduction ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
Foveal Congenital Simple Hamartoma of Retinal Pigment Epithelium: A Report of Two Cases.
Autorzy :
Badawi AH; Vitreoretinal Division, King Khalid Eye Specialist Hospital, Riyadh, Saudi Arabia.
Magliyah M; Vitreoretinal Division, King Khalid Eye Specialist Hospital, Riyadh, Saudi Arabia.; Department of Ophthalmology, Prince Mohammed Medical City, AlJouf, Saudi Arabia.
Allam K; Department of Ophthalmology, King Saud Medical City, Riyadh, Saudi Arabia.
Alzahrani YA; Ophthalmology Department, King Fahad Medical City, Riyadh, Saudi Arabia.
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Źródło :
Middle East African journal of ophthalmology [Middle East Afr J Ophthalmol] 2020 Jul 20; Vol. 27 (2), pp. 128-130. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Typ publikacji :
Case Reports; Journal Article
Journal Info :
Publisher: Medknow Publications and Media Country of Publication: India NLM ID: 101521797 Publication Model: eCollection Cited Medium: Internet ISSN: 0975-1599 (Electronic) Linking ISSN: 09749233 NLM ISO Abbreviation: Middle East Afr J Ophthalmol Subsets: MEDLINE
MeSH Terms :
Hamartoma/*congenital
Retinal Diseases/*congenital
Retinal Pigment Epithelium/*abnormalities
Adult ; Diagnostic Techniques, Ophthalmological ; Electroretinography ; Fluorescein Angiography ; Fovea Centralis/pathology ; Fundus Oculi ; Hamartoma/diagnosis ; Humans ; Male ; Middle Aged ; Multimodal Imaging ; Retinal Diseases/diagnosis ; Retinal Pigment Epithelium/pathology ; Tomography, Optical Coherence/methods ; Visual Acuity/physiology
Czasopismo naukowe
Tytuł :
Ambient Air Pollution Associations with Retinal Morphology in the UK Biobank.
Autorzy :
Chua SYL; .; .
Khawaja AP; .; .
Dick AD; .; .
Morgan J; .
Dhillon B; .; .
Lotery AJ; .
Strouthidis NG; .
Reisman C; .
Peto T; .
Khaw PT; .; .
Foster PJ; .; .
Patel PJ; .
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Corporate Authors :
UK Biobank Eye and Vision Consortium
Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 May 11; Vol. 61 (5), pp. 32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Subsets: MEDLINE
MeSH Terms :
Air Pollution/*adverse effects
Nerve Fibers/*drug effects
Nitrogen Oxides/*adverse effects
Particulate Matter/*adverse effects
Photoreceptor Cells, Vertebrate/*drug effects
Retinal Ganglion Cells/*drug effects
Retinal Pigment Epithelium/*drug effects
Adult ; Aged ; Biological Specimen Banks ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Nerve Fibers/pathology ; Photoreceptor Cells, Vertebrate/pathology ; Retinal Diseases/chemically induced ; Retinal Ganglion Cells/pathology ; Retinal Pigment Epithelium/diagnostic imaging ; Retinal Pigment Epithelium/pathology ; Surveys and Questionnaires ; Tomography, Optical Coherence ; United Kingdom
Czasopismo naukowe
Tytuł :
Complete RPE and outer retinal atrophy in patients receiving anti-VEGF treatment for neovascular age-related macular degeneration.
Autorzy :
Eng VA; Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, California, United States of America.
Rayess N; Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, California, United States of America.
Nguyen HV; Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, California, United States of America.
Leng T; Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, California, United States of America.
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Źródło :
PloS one [PLoS One] 2020 May 05; Vol. 15 (5), pp. e0232353. Date of Electronic Publication: 2020 May 05 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Retinal Degeneration/*drug therapy
Retinal Degeneration/*pathology
Retinal Pigment Epithelium/*drug effects
Retinal Pigment Epithelium/*pathology
Vascular Endothelial Growth Factor A/*antagonists & inhibitors
Aged ; Aged, 80 and over ; Atrophy ; Bevacizumab/therapeutic use ; Female ; Follow-Up Studies ; Humans ; Image Interpretation, Computer-Assisted ; Intravitreal Injections ; Male ; Ranibizumab/therapeutic use ; Receptors, Vascular Endothelial Growth Factor/therapeutic use ; Recombinant Fusion Proteins/therapeutic use ; Retinal Degeneration/diagnostic imaging ; Retinal Pigment Epithelium/diagnostic imaging ; Retrospective Studies ; Tomography, Optical Coherence ; Treatment Outcome
Czasopismo naukowe
Tytuł :
mTORC1 signaling pathway regulates macrophages in choroidal neovascularization.
Autorzy :
Wang C; Department of Ophthalmology, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Ma J; Department of Ophthalmology, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Xu M; Department of Ophthalmology, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Gao J; Department of Biotechnology Drug, North China Pharmaceutical Group New Drug R&D Co., Ltd., Shijiazhuang, 052260, Hebei, China.
Zhao W; Department of Biotechnology Drug, North China Pharmaceutical Group New Drug R&D Co., Ltd., Shijiazhuang, 052260, Hebei, China.
Yao Y; Department of Ophthalmology, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Shang Q; Department of Ophthalmology, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 May; Vol. 121, pp. 72-80. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Pergamon Press Country of Publication: England NLM ID: 7905289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9142 (Electronic) Linking ISSN: 01615890 NLM ISO Abbreviation: Mol. Immunol. Subsets: MEDLINE
MeSH Terms :
Choroidal Neovascularization/*immunology
Macrophages/*immunology
Mechanistic Target of Rapamycin Complex 1/*metabolism
Retinal Pigment Epithelium/*pathology
Animals ; Cell Line, Tumor ; Choroidal Neovascularization/etiology ; Choroidal Neovascularization/pathology ; Disease Models, Animal ; Female ; Humans ; Lasers/adverse effects ; Macrophages/metabolism ; Mechanistic Target of Rapamycin Complex 1/immunology ; Mice ; Retinal Pigment Epithelium/immunology ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
Spectral-Domain Optical Coherence Tomography Analysis of Fibrotic Lesions in Neovascular Age-Related Macular Degeneration.
Autorzy :
Souied EH; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France; Clinical Research Center, GRC Macula, and Biological Ressources Center, Centre Hospitalier Intercommunal de Créteil, Créteil, France. Electronic address: .
Addou-Regnard M; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Ohayon A; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Semoun O; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Querques G; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Blanco-Garavito R; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Bunod R; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Jung C; Clinical Research Center, GRC Macula, and Biological Ressources Center, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Sikorav A; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France.
Miere A; Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris Est Créteil, Créteil, France; Clinical Research Center, GRC Macula, and Biological Ressources Center, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
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Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2020 Jun; Vol. 214, pp. 151-171. Date of Electronic Publication: 2020 Feb 27.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am. J. Ophthalmol. Subsets: Core Clinical (AIM); MEDLINE
MeSH Terms :
Tomography, Optical Coherence*
Choroidal Neovascularization/*diagnostic imaging
Retina/*pathology
Retinal Pigment Epithelium/*pathology
Wet Macular Degeneration/*diagnostic imaging
Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/therapeutic use ; Choroidal Neovascularization/drug therapy ; Cross-Sectional Studies ; Female ; Fibrosis ; Fluorescein Angiography ; Humans ; Intravitreal Injections ; Male ; Multimodal Imaging ; Retina/diagnostic imaging ; Retinal Pigment Epithelium/diagnostic imaging ; Retrospective Studies ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Visual Acuity ; Wet Macular Degeneration/drug therapy
Czasopismo naukowe
Tytuł :
KCNJ13 Gene Deletion Impairs Cell Alignment and Phagocytosis in Retinal Pigment Epithelium Derived from Human-Induced Pluripotent Stem Cells.
Autorzy :
Kanzaki Y; .; .
Fujita H; .
Sato K; .
Hosokawa M; .
Matsumae H; .
Shiraga F; .
Morizane Y; .
Ohuchi H; .
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 May 11; Vol. 61 (5), pp. 38.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Subsets: MEDLINE
MeSH Terms :
Gene Deletion*
Induced Pluripotent Stem Cells/*cytology
Phagocytosis/*physiology
Potassium Channels, Inwardly Rectifying/*genetics
Retinal Pigment Epithelium/*physiology
Animals ; Blotting, Western ; CRISPR-Associated Protein 9 ; Cell Differentiation ; Cell Line ; Gene Knockout Techniques ; Humans ; Leber Congenital Amaurosis/pathology ; Microscopy, Electron, Transmission ; Microscopy, Fluorescence ; Real-Time Polymerase Chain Reaction ; Retinal Photoreceptor Cell Outer Segment/metabolism ; Retinal Pigment Epithelium/ultrastructure ; Swine
Czasopismo naukowe
Tytuł :
Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium.
Autorzy :
Liu J; .
Taylor RL; .
Baines RA; .
Swanton L; .
Freeman S; .
Corneo B; .
Patel A; .
Marmorstein A; .
Knudsen T; .
Black GC; .; .
Manson F; .
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 May 11; Vol. 61 (5), pp. 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Bestrophins/*genetics
Eye Diseases, Hereditary/*drug therapy
Gene Expression Regulation/*physiology
Glycolates/*pharmacology
Phenylbutyrates/*pharmacology
Retinal Diseases/*drug therapy
Retinal Pigment Epithelium/*drug effects
Blotting, Western ; Cell Membrane/metabolism ; Chloride Channels/metabolism ; Cycloheximide/pharmacology ; Electrophoresis, Polyacrylamide Gel ; Eye Diseases, Hereditary/genetics ; Eye Diseases, Hereditary/metabolism ; Genes, Recessive ; HEK293 Cells/drug effects ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Microscopy, Fluorescence ; Patch-Clamp Techniques ; Real-Time Polymerase Chain Reaction ; Retinal Diseases/genetics ; Retinal Diseases/metabolism ; Retinal Pigment Epithelium/metabolism ; Transfection
SCR Disease Name :
Bestrophinopathy
Czasopismo naukowe
Tytuł :
Neonatal endotoxin stimulation is associated with a long-term bronchiolar epithelial expression of innate immune and anti-allergic markers that attenuates the allergic response.
Autorzy :
García LN; Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de la Salud (INICSA), Córdoba, Argentina.
Leimgruber C; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de la Salud (INICSA), Córdoba, Argentina.
Nicola JP; Departamento de Bioquímica Clínica, Universidad Nacional de Córdoba, Facultad de Ciencias Químicas, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Córdoba, Argentina.
Quintar AA; Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de la Salud (INICSA), Córdoba, Argentina.
Maldonado CA; Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Córdoba, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Investigaciones en Ciencias de la Salud (INICSA), Córdoba, Argentina.
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Źródło :
PloS one [PLoS One] 2020 May 07; Vol. 15 (5), pp. e0226233. Date of Electronic Publication: 2020 May 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Immunity, Innate*
Asthma/*immunology
Bronchioles/*drug effects
Bronchioles/*immunology
Cytokines/*metabolism
Epithelium/*immunology
Lipopolysaccharides/*immunology
Lipopolysaccharides/*pharmacology
Allergens/immunology ; Animals ; Animals, Newborn ; Asthma/prevention & control ; Disease Models, Animal ; Epithelium/drug effects ; Mice ; Mice, Inbred BALB C ; Ovalbumin/immunology ; Ovalbumin/pharmacology ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology
Czasopismo naukowe
Tytuł :
Retinal dystrophy associated with Danon disease and pathogenic mechanism through LAMP2-mutated retinal pigment epithelium.
Autorzy :
Fukushima M; Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan.
Inoue T; Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan.
Miyai T; Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan.
Obata R; Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan.
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Źródło :
European journal of ophthalmology [Eur J Ophthalmol] 2020 May; Vol. 30 (3), pp. 570-578. Date of Electronic Publication: 2019 Mar 05.
Typ publikacji :
Case Reports; Journal Article
Journal Info :
Publisher: SAGE Publishing Country of Publication: United States NLM ID: 9110772 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-6016 (Electronic) Linking ISSN: 11206721 NLM ISO Abbreviation: Eur J Ophthalmol Subsets: MEDLINE
MeSH Terms :
Mutation*
Glycogen Storage Disease Type IIb/*complications
Lysosomal-Associated Membrane Protein 2/*genetics
Retinal Dystrophies/*etiology
Retinal Dystrophies/*genetics
Retinal Pigment Epithelium/*metabolism
Animals ; Blotting, Western ; Cells, Cultured ; Electroretinography ; Gene Expression ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Confocal ; Middle Aged ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Real-Time Polymerase Chain Reaction ; Retina/pathology ; Retinal Dystrophies/diagnosis ; Retinal Pigment Epithelium/pathology ; Retrospective Studies ; Slit Lamp Microscopy ; Visual Field Tests
Czasopismo naukowe
Tytuł :
Repair Process Impairment by Pseudomonas aeruginosa in Epithelial Tissues: Major Features and Potential Therapeutic Avenues.
Autorzy :
Ruffin M; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Département de Médecine, Université de Montréal, Montréal, QC, Canada.; INSERM, Centre de Recherche Saint-Antoine, CRSA, Sorbonne Université, Paris, France.
Brochiero E; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.; Département de Médecine, Université de Montréal, Montréal, QC, Canada.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2019 May 31; Vol. 9, pp. 182. Date of Electronic Publication: 2019 May 31 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info :
Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
MeSH Terms :
Epithelium/*microbiology
Epithelium/*physiology
Pseudomonas Infections/*microbiology
Pseudomonas aeruginosa/*physiology
Alveolar Epithelial Cells ; Animals ; Drug Resistance, Multiple, Bacterial ; Epithelium/injuries ; Epithelium, Corneal ; Humans ; Incidence ; Pseudomonas Infections/therapy ; Pseudomonas aeruginosa/isolation & purification ; Respiratory Mucosa
Czasopismo naukowe
Tytuł :
Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance.
Autorzy :
Haldar S; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Mishra R; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Billet S; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Thiruvalluvan M; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Placencio-Hickok VR; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Madhav A; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Duong F; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Angara B; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.; Department of Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073.
Agarwal P; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Tighiouart M; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Posadas EM; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Bhowmick NA; Department of Medicine, Samuel Ochin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048; .; Department of Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Apr 14; Vol. 117 (15), pp. 8515-8523. Date of Electronic Publication: 2020 Apr 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info :
Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
MeSH Terms :
Drug Resistance, Neoplasm*
Anaphylatoxins/*metabolism
Cancer-Associated Fibroblasts/*pathology
DNA, Mitochondrial/*metabolism
Docetaxel/*pharmacology
Epithelium/*pathology
Prostatic Neoplasms/*pathology
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis ; Cancer-Associated Fibroblasts/drug effects ; Cancer-Associated Fibroblasts/metabolism ; Epithelium/drug effects ; Epithelium/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; Paracrine Communication ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/metabolism ; Toll-Like Receptor 9/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells.
Autorzy :
Korhonen E; .; .
Bisevac J; .; .
Hyttinen JMT; .
Piippo N; .
Hytti M; .
Kaarniranta K; .; .
Petrovski G; .; .
Kauppinen A; .
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 Apr 09; Vol. 61 (4), pp. 7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Subsets: MEDLINE
MeSH Terms :
Ultraviolet Rays*
Epithelium, Corneal/*drug effects
Epithelium, Corneal/*radiation effects
Inflammasomes/*metabolism
Urocanic Acid/*pharmacology
Blotting, Western ; Caspase 1/metabolism ; Cells, Cultured ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Epithelium, Corneal/metabolism ; Humans ; Inflammation/prevention & control ; Interleukin-18/metabolism ; Interleukin-1beta/metabolism ; Lipopolysaccharides/toxicity ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Airborne Particulates Affect Corneal Homeostasis and Immunity.
Autorzy :
Somayajulu M
Ekanayaka S
McClellan SA
Bessert D
Pitchaikannu A
Zhang K
Hazlett LD
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Źródło :
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2020 Apr 09; Vol. 61 (4), pp. 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Subsets: MEDLINE
MeSH Terms :
Epithelium, Corneal/*drug effects
Homeostasis/*drug effects
Immunity/*drug effects
Particulate Matter/*pharmacology
Animals ; Biomarkers/metabolism ; Blotting, Western ; Cell Survival ; Cells, Cultured ; Corneal Ulcer/drug therapy ; Corneal Ulcer/metabolism ; Corneal Ulcer/pathology ; Enzyme-Linked Immunosorbent Assay ; Epithelium, Corneal/metabolism ; Epithelium, Corneal/pathology ; Eye Infections, Bacterial/drug therapy ; Eye Infections, Bacterial/metabolism ; Eye Infections, Bacterial/pathology ; Female ; Humans ; Mice ; Mice, Inbred C57BL ; Oxidative Stress/physiology ; Pseudomonas Infections/drug therapy ; Pseudomonas Infections/metabolism ; Pseudomonas Infections/pathology ; RNA, Messenger/genetics ; Reactive Oxygen Species/metabolism ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells.
Autorzy :
Goswami DG; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Kant R; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Ammar DA; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Agarwal C; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Gomez J; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Agarwal R; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Saba LM; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Fritz KS; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA.
Tewari-Singh N; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, 80045, USA; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan, 48824, USA. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Apr 01; Vol. 322, pp. 1-11. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Apoptosis/*drug effects
Epithelial Cells/*drug effects
Epithelium, Corneal/*drug effects
Hydrocarbons, Chlorinated/*toxicity
Oxidative Stress/*drug effects
Pesticides/*toxicity
Protein Carbonylation/*drug effects
Caspase 3/metabolism ; Cells, Cultured ; Cyclooxygenase 2/metabolism ; DNA Damage ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Epithelium, Corneal/metabolism ; Epithelium, Corneal/pathology ; Heme Oxygenase-1/metabolism ; Histones/metabolism ; Humans ; Inflammation Mediators/metabolism ; JNK Mitogen-Activated Protein Kinases/metabolism ; Lipid Peroxidation ; Phosphorylation ; Poly(ADP-ribose) Polymerases/metabolism ; Signal Transduction ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Autorzy :
Zhang L; Central Laboratory, Department of Laboratory Medicine, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, Taizhou, Zhejiang Province, China.
Zhou Y; Central Laboratory, Department of Laboratory Medicine, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, Taizhou, Zhejiang Province, China.
Xia Q; Central Laboratory, Department of Laboratory Medicine, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, Taizhou, Zhejiang Province, China.
Chen Y; Central Laboratory, Department of Laboratory Medicine, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, Taizhou, Zhejiang Province, China.
Li J; Central Laboratory, Department of Laboratory Medicine, Huangyan Hospital of Wenzhou Medical University, Taizhou First People's Hospital, Taizhou, Zhejiang Province, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Apr 01; Vol. 322, pp. 77-86. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Autophagy/*drug effects
Endoplasmic Reticulum Stress/*drug effects
Epithelial Cells/*drug effects
Mitochondria/*drug effects
Oxidative Stress/*drug effects
Retinal Pigment Epithelium/*drug effects
Vitamin A/*toxicity
Apoptosis/drug effects ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Cell Line ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Humans ; Mitochondria/metabolism ; Mitochondria/pathology ; Reactive Oxygen Species/metabolism ; Retinal Pigment Epithelium/metabolism ; Retinal Pigment Epithelium/pathology ; Signal Transduction
Czasopismo naukowe

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