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Tytuł :
Immunoinformatics approach for designing a universal multiepitope vaccine against Chandipura Virus.
Autorzy :
Banik A; Department of Plant and Environmental Biotechnology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
Sinha S; Department of Animal and Fish Biotechnology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
Ahmed SR; Department of Plant and Environmental Biotechnology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
Chowdhury MMH; Department of Microbiology, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh. Electronic address: .
Mukta S; Department of Plant and Environmental Biotechnology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
Ahmed N; Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
Rani NA; Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2022 Jan; Vol. 162, pp. 105358. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes, B-Lymphocyte*/genetics
Vaccines*
Computational Biology ; Epitopes, T-Lymphocyte/genetics ; Humans ; Molecular Docking Simulation ; Vaccines, Subunit ; Vesiculovirus/genetics
Czasopismo naukowe
Tytuł :
Mining of linear B cell epitopes of SARS-CoV-2 ORF8 protein from COVID-19 patients.
Autorzy :
Wang X; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Lam JY; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Chen L; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Au SW; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.
To KKW; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Yuen KY; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Kok KH; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong SAR, People's Republic of China.; AIDS Institute, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1016-1023.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes, B-Lymphocyte*
COVID-19/*immunology
SARS-CoV-2/*immunology
Viral Proteins/*chemistry
Animals ; Antibodies, Viral ; Cricetinae ; Humans ; Immunodominant Epitopes ; Mesocricetus ; Models, Molecular ; Protein Conformation ; Viral Proteins/immunology
Czasopismo naukowe
Tytuł :
Immunoinformatics and molecular docking studies reveal a novel Multi-Epitope peptide vaccine against pneumonia infection.
Autorzy :
Mahapatra SR; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India. Electronic address: .
Dey J; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India. Electronic address: .
Kaur T; Biotechnology Industry Research Assistance Council (BIRAC), India.
Sarangi R; Kalinga Institute of Medical Sciences, KIIT Deemed to Be University, Bhubaneswar 751024, India.
Bajoria AA; Kalinga Institute of Dental Sciences, KIIT Deemed to Be University, Bhubaneswar 751024, India.
Kushwaha GS; KIIT-Technology Business Incubator (KIIT-TBI), Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India; Transcription Regulation group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi 110067, India.
Misra N; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India; KIIT-Technology Business Incubator (KIIT-TBI), Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India. Electronic address: .
Suar M; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India; KIIT-Technology Business Incubator (KIIT-TBI), Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar 751024, India. Electronic address: .
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Źródło :
Vaccine [Vaccine] 2021 Oct 08; Vol. 39 (42), pp. 6221-6237. Date of Electronic Publication: 2021 Sep 21.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes, B-Lymphocyte*
Pneumonia*
Computational Biology ; Epitopes, T-Lymphocyte/genetics ; Humans ; Molecular Docking Simulation ; Vaccines, Subunit
Czasopismo naukowe
Tytuł :
Production and Immunological Evaluation of Epitope-based Preventative Pneumococcal Candidate Vaccine Comprising Immunodominant Epitopes from PspA, CbpA, PhtD and PiuA Antigens.
Autorzy :
Dorosti H; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Nezafat N; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Heidari R; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ghoshoon MB; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Gholami A; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Dehshahri A; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Erfani N; Cancer Immunology Group, Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Rahbar MR; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ghasemi Y; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło :
Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2021 Oct 06; Vol. 22 (14), pp. 1900-1909.
Typ publikacji :
Journal Article
MeSH Terms :
Immunodominant Epitopes*
Pneumococcal Vaccines*
Animals ; Bacterial Proteins ; Epitopes, T-Lymphocyte ; Mice ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
Identification of the Dominant T-Cell Epitopes of Lit v 1 Shrimp Major Allergen and Their Functional Overlap with Known B-Cell Epitopes.
Autorzy :
Xu LL; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
Gasset M; Institute of Physical Chemistry Rocasolano (IQFR), Spanish National Research Council (CSIC), 28006 Madrid, Spain.
Lin H; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
Yu C; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
Zhao JL; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
Dang XW; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
Li ZX; College of Food Science and Engineering, Ocean University of China, No.5, Yushan Road, Qingdao, Shandong Province 266003, P. R. China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2021 Jul 07; Vol. 69 (26), pp. 7420-7428. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Allergens*
Epitopes, B-Lymphocyte*
Amino Acid Sequence ; Epitopes, T-Lymphocyte ; Humans ; Tropomyosin
Czasopismo naukowe
Tytuł :
Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2.
Autorzy :
Low JS; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Vaqueirinho D; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Mele F; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Foglierini M; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Jerak J; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Perotti M; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Jarrossay D; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Jovic S; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Perez L; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.
Cacciatore R; Laboratory of Immunogenetics, Department of Transfusion Medicine and Immuno-Hematology, Fondazione I.R.C.C.S. Policlinico S. Matteo, 27100 Pavia, Italy.
Terrot T; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Pellanda AF; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Biggiogero M; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Garzoni C; Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland.
Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Department of Internal Medicine, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Prince of Wales Hospital Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia.
Ceschi A; Clinical Trial Unit, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland.
Lanzavecchia A; National Institute of Molecular Genetics, 20122 Milano, Italy.
Sallusto F; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland. .; Institute of Microbiology, ETH Zürich, 8093 Zurich, Switzerland.
Cassotta A; Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland. .
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Źródło :
Science (New York, N.Y.) [Science] 2021 Jun 18; Vol. 372 (6548), pp. 1336-1341. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunodominant Epitopes*
CD4-Positive T-Lymphocytes/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Coronavirus/immunology ; Cross Reactions ; Epitopes, T-Lymphocyte/immunology ; Genes, T-Cell Receptor beta ; HLA-DP Antigens/immunology ; HLA-DR Antigens/immunology ; Humans ; Immunologic Memory ; Nucleocapsid Proteins/immunology ; Protein Domains ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Spike Glycoprotein, Coronavirus/chemistry ; T Follicular Helper Cells/immunology ; T-Lymphocyte Subsets/immunology
Czasopismo naukowe
Tytuł :
New highly antigenic linear B cell epitope peptides from PvAMA-1 as potential vaccine candidates.
Autorzy :
Fantin RF; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.; School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Fraga VG; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Lopes CA; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
de Azevedo IC; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Reis-Cunha JL; Department of Preventive Veterinary, Medicine Federal University of Minas Gerais, Belo Horizonte, Brazil.
Pereira DB; Tropical Medicine Research Center, Porto Velho, Rondônia, Brazil.
Lobo FP; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
de Oliveira MM; Tropical Medicine Research Center, Porto Velho, Rondônia, Brazil.
Dos Santos AC; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Bartholomeu DC; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Fujiwara RT; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Bueno LL; Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
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Źródło :
PloS one [PLoS One] 2021 Nov 02; Vol. 16 (11), pp. e0258637. Date of Electronic Publication: 2021 Nov 02 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Protozoan/*immunology
Epitopes, B-Lymphocyte/*immunology
Malaria Vaccines/*immunology
Membrane Proteins/*immunology
Peptides/*immunology
Plasmodium vivax/*immunology
Protozoan Proteins/*immunology
Adult ; Amino Acid Sequence ; Antibody Formation/immunology ; Case-Control Studies ; Female ; Humans ; Immunodominant Epitopes/immunology ; Immunoglobulin G/immunology ; Malaria, Vivax/epidemiology ; Malaria, Vivax/immunology ; Male ; Middle Aged ; Peptides/chemistry ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus.
Autorzy :
Fadaka AO; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa. .
Sibuyi NRS; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa.
Martin DR; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa.
Goboza M; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa.
Klein A; Plant Omics Laboratory, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Bellville, 7535, Cape Town, South Africa.
Madiehe AM; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa.; Nanobiotechnology Research Group, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa.
Meyer M; Department of Science and Innovation/Mintek Nanotechnology Innovation Centre, Biolabels Node, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Bellville, South Africa. .
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Źródło :
Scientific reports [Sci Rep] 2021 Oct 05; Vol. 11 (1), pp. 19707. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Molecular*
Computational Biology/*methods
Dengue Vaccines/*immunology
Dengue Virus/*immunology
Epitopes/*chemistry
Epitopes/*immunology
Vaccinology/*methods
Amino Acid Sequence ; Antigens, Viral ; Chemical Phenomena ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/immunology ; Genetic Engineering ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Structure-Activity Relationship ; Vaccine Development
Czasopismo naukowe
Tytuł :
Identification of potential SLA-I-restricted CTL epitopes within the M protein of porcine reproductive and respiratory syndrome virus.
Autorzy :
Liang C; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Xia Q; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Zhou J; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Liu H; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Chen Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Liu Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Ding P; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Qi Y; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
Wang A; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2021 Aug; Vol. 259, pp. 109131. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes, T-Lymphocyte/*immunology
Histocompatibility Antigens Class I/*immunology
Porcine respiratory and reproductive syndrome virus/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Viral Matrix Proteins/*genetics
Viral Matrix Proteins/*immunology
Amino Acid Sequence ; Animals ; Cell Line ; Computer Simulation ; Epitopes, T-Lymphocyte/genetics ; Immunodominant Epitopes/immunology ; Porcine Reproductive and Respiratory Syndrome/immunology ; Porcine Reproductive and Respiratory Syndrome/virology ; Protein Binding ; Swine
Czasopismo naukowe
Tytuł :
SARS-CoV-2 specific memory T cell epitopes identified in COVID-19-recovered subjects.
Autorzy :
Zhao J; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Wang L; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Schank M; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Dang X; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Lu Z; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States.
Cao D; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Khanal S; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Nguyen LN; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Nguyen LNT; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Zhang J; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Zhang Y; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Adkins JL; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States.
Baird EM; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States.
Wu XY; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Ning S; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Gazzar ME; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States.
Moorman JP; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States; Hepatitis (HCV/HBV/HIV) Program, James H. Quillen VA Medical Center, Department of Veterans Affairs, Johnson City, Tennessee 37614, United States.
Yao ZQ; Center of Excellence for Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee 37614, United States; Division of Infectious Diseases, Department of Internal Medicine, Quillen College of Medicine, ETSU, Johnson City, Tennessee 37614, United States; Hepatitis (HCV/HBV/HIV) Program, James H. Quillen VA Medical Center, Department of Veterans Affairs, Johnson City, Tennessee 37614, United States. Electronic address: .
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Źródło :
Virus research [Virus Res] 2021 Oct 15; Vol. 304, pp. 198508. Date of Electronic Publication: 2021 Jul 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Pandemics*
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
COVID-19/*immunology
Epitopes, T-Lymphocyte/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adult ; CD8-Positive T-Lymphocytes/cytology ; COVID-19/epidemiology ; Female ; Humans ; Immunodominant Epitopes/immunology ; Male ; Middle Aged ; SARS-CoV-2/immunology ; Young Adult
Czasopismo naukowe
Tytuł :
Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Autorzy :
Szeto C; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Nguyen AT; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Lobos CA; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Chatzileontiadou DSM; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Jayasinghe D; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Grant EJ; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Riboldi-Tunnicliffe A; Australian Synchrotron, ANSTO, Clayton, VIC 3168, Australia.
Smith C; QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD 4072, Australia.
Gras S; Viral and Structural Immunology Laboratory, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, School of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia.; Viral and Structural Immunology Laboratory, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
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Źródło :
Cells [Cells] 2021 Oct 03; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
SARS-CoV-2*
COVID-19/*immunology
COVID-19/*virology
Epitopes, T-Lymphocyte/*chemistry
HLA-A2 Antigen/*immunology
Receptors, Antigen, T-Cell/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
CD8-Positive T-Lymphocytes/cytology ; Crystallography, X-Ray ; Cytokines/metabolism ; Epitopes/chemistry ; HLA-A2 Antigen/chemistry ; Humans ; Mutation ; Peptides/chemistry ; Protein Binding ; Protein Denaturation ; Protein Folding ; Surface Plasmon Resonance ; T-Lymphocytes, Cytotoxic/immunology
Czasopismo naukowe
Tytuł :
Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Autorzy :
Aljedani SS; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, Washington, United States of America.
Liban TJ; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, Washington, United States of America.
Tran K; The Scripps Research Institute, IAVI Neutralizing Antibody Center, La Jolla, California, United States of America.
Phad G; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Singh S; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, Washington, United States of America.
Dubrovskaya V; The Scripps Research Institute, IAVI Neutralizing Antibody Center, La Jolla, California, United States of America.
Pushparaj P; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Martinez-Murillo P; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Rodarte J; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, Washington, United States of America.
Mileant A; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America.
Mangala Prasad V; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America.
Kinzelman R; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America.
O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, United States of America.
Karlsson Hedestam GB; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Wyatt RT; The Scripps Research Institute, IAVI Neutralizing Antibody Center, La Jolla, California, United States of America.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
Pancera M; Fred Hutchinson Cancer Research Center, Vaccine and Infectious Disease Division, Seattle, Washington, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2021 Sep 24; Vol. 17 (9), pp. e1009543. Date of Electronic Publication: 2021 Sep 24 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
AIDS Vaccines/*immunology
Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
Immunodominant Epitopes/*immunology
env Gene Products, Human Immunodeficiency Virus/*immunology
Animals ; Antibodies, Monoclonal ; Epitopes, B-Lymphocyte/immunology ; Female ; HIV Infections/immunology ; HIV-1/immunology ; Macaca mulatta
Czasopismo naukowe
Tytuł :
Immunogenicity of Foot-and-Mouth Disease Virus Dendrimer Peptides: Need for a T-Cell Epitope and Ability to Elicit Heterotypic Responses.
Autorzy :
Cañas-Arranz R; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
de León P; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
Defaus S; Departament de Ciències Experimentals i de la Salut (DCEXS-UPF), 08003 Barcelona, Spain.
Torres E; Centro de Investigación en Sanidad Animal (CISA-INIA), 28130 Valdeolmos, Spain.
Forner M; Departament de Ciències Experimentals i de la Salut (DCEXS-UPF), 08003 Barcelona, Spain.
Bustos MJ; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
Andreu D; Departament de Ciències Experimentals i de la Salut (DCEXS-UPF), 08003 Barcelona, Spain.
Blanco E; Centro de Investigación en Sanidad Animal (CISA-INIA), 28130 Valdeolmos, Spain.
Sobrino F; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 04; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Dendrimers/*chemistry
Epitopes, T-Lymphocyte/*immunology
Foot-and-Mouth Disease Virus/*immunology
Peptides/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Epitopes, B-Lymphocyte/immunology ; Female ; Foot-and-Mouth Disease/immunology ; Foot-and-Mouth Disease/virology ; Mice ; Species Specificity ; Swine
Czasopismo naukowe
Tytuł :
Subtractive proteomics and immunoinformatics approaches to explore Bartonella bacilliformis proteome (virulence factors) to design B and T cell multi-epitope subunit vaccine.
Autorzy :
Gul H; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan.
Ali SS; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Saleem S; National Center for Bioinformatics, Quaid-e-Azam University, Islamabad, Pakistan.
Khan S; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan.
Khan J; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Wadood A; Department of Biochemistry, Abdul Wali Khan University, Mardan, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Rehman AU; Department of Bioinformatics and Biological statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, PR China. Electronic address: .
Ullah Z; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan.
Ali S; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Khan H; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan.
Hussain Z; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Akbar F; Centre for Biotechnology and Microbiology, University of Swat, Swat, Khyber Pakhtunkhwa, Pakistan. Electronic address: .
Khan A; Department of Bioinformatics and Biological statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, PR China. Electronic address: .
Wei DQ; Department of Bioinformatics and Biological statistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, PR China; State Key Laboratory of Microbial Metabolism, Shanghai-Islamabad-Belgrade Joint Innovation Center on Antibacterial Resistances, Joint Laboratory of International Cooperation in Metabolic and Developmental Sciences, Ministry of Education and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, PR China; Peng Cheng Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nashan District, Shenzhen, Guangdong 518055, PR China. Electronic address: .
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Źródło :
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2020 Nov; Vol. 85, pp. 104551. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Computational Biology*/methods
Epitopes*/chemistry
Epitopes*/immunology
Proteome*
Proteomics*
Bacterial Vaccines/*immunology
Bartonella Infections/*microbiology
Bartonella bacilliformis/*metabolism
Bacterial Vaccines/genetics ; Bartonella Infections/immunology ; Bartonella Infections/prevention & control ; Bartonella bacilliformis/immunology ; Bartonella bacilliformis/pathogenicity ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/immunology ; Host-Pathogen Interactions/immunology ; Humans ; Models, Molecular ; Structure-Activity Relationship ; Vaccinology ; Virulence Factors/immunology
Czasopismo naukowe
Tytuł :
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19.
Autorzy :
Grifoni A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Sidney J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Vita R; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Peters B; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Crotty S; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
Weiskopf D; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Sette A; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2021 Jul 14; Vol. 29 (7), pp. 1076-1092. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Adaptive Immunity*
COVID-19/*immunology
Epitopes, T-Lymphocyte/*immunology
SARS-CoV-2/*immunology
Antigens, Viral ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cross Reactions ; Epitopes ; Humans ; Immunodominant Epitopes
Czasopismo naukowe
Tytuł :
Designing a multi-epitope vaccine candidate to combat MERS-CoV by employing an immunoinformatics approach.
Autorzy :
Mahmud S; Microbiology Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh.
Rafi MO; Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh.
Paul GK; Microbiology Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh.
Promi MM; Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh.
Shimu MSS; Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh.
Biswas S; Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh.
Emran TB; Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh.
Dhama K; Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243122, Uttar Pradesh, India.
Alyami SA; Department of Mathematics and Statistics, Imam Mohammad Ibn Saud Islamic University, Riyadh, 11432, Saudi Arabia.
Moni MA; Faculty of Medicine, WHO Collaborating Centre on eHealth, UNSW Digital Health, School of Public Health and Community Medicine, UNSW Sydney, Sydney, NSW, 2052, Australia. .
Saleh MA; Microbiology Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, 6505, Bangladesh. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jul 29; Vol. 11 (1), pp. 15431. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Epitopes/*immunology
Middle East Respiratory Syndrome Coronavirus/*immunology
Vaccines/*immunology
Computational Biology ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Epitopes, B-Lymphocyte/genetics ; Epitopes, B-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/immunology ; Humans ; Immunogenicity, Vaccine/immunology ; Middle East Respiratory Syndrome Coronavirus/genetics ; Middle East Respiratory Syndrome Coronavirus/pathogenicity ; Models, Molecular ; Molecular Docking Simulation ; Phylogeny ; Protein Binding ; Spike Glycoprotein, Coronavirus/immunology ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Helper-Inducer/immunology ; Vaccines/pharmacology ; Vaccines, DNA ; Vaccines, Subunit/immunology ; Viral Vaccines/immunology
Czasopismo naukowe
Tytuł :
Immunoinformatics designed T cell multi epitope dengue peptide vaccine derived from non structural proteome.
Autorzy :
Krishnan G S; Domain of Bioinformatics, School of Bio-Engineering and Bio-Sciences, Lovely Professional University, Punjab, India. Electronic address: .
Joshi A; Domain of Bioinformatics, School of Bio-Engineering and Bio-Sciences, Lovely Professional University, Punjab, India. Electronic address: .
Akhtar N; Domain of Bioinformatics, School of Bio-Engineering and Bio-Sciences, Lovely Professional University, Punjab, India. Electronic address: .
Kaushik V; Domain of Bioinformatics, School of Bio-Engineering and Bio-Sciences, Lovely Professional University, Punjab, India. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2021 Jan; Vol. 150, pp. 104728. Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Dengue*/prevention & control
Epitopes, T-Lymphocyte*
Animals ; Computational Biology ; Epitopes, B-Lymphocyte ; Humans ; Molecular Docking Simulation ; Mosquito Vectors ; Peptides ; Proteome ; T-Lymphocytes ; Vaccines, Subunit
Czasopismo naukowe
Tytuł :
Vaccines Targeting Numerous Coronavirus Antigens, Ensuring Broader Global Population Coverage: Multi-epitope and Multi-patch Vaccines.
Autorzy :
Srivastava S; Infection Biology Group, Indian Foundation for Fundamental Research, Raebareli, Uttar Pradesh, India. .
Chatziefthymiou SD; Deutsches Elektronen-Synchrotron (DESY), Hamburg, Germany.; Department of Structural Infection Biology, Center for Structural Systems Biology (CSSB), Helmholtz-Center for Infection Research (HZI), Hamburg, Germany.
Kolbe M; Department of Structural Infection Biology, Center for Structural Systems Biology (CSSB), Helmholtz-Center for Infection Research (HZI), Hamburg, Germany. .; MIN-Faculty University Hamburg, Hamburg, Germany. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2410, pp. 149-175.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/prevention & control
Epitopes, B-Lymphocyte*
Epitopes, T-Lymphocyte*
Viral Vaccines*/immunology
Coronavirus Infections/*prevention & control
Antigens, Viral/immunology ; Humans ; Proteome ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
A reverse vaccinology and immunoinformatics approach for designing a multiepitope vaccine against SARS-CoV-2.
Autorzy :
Jahangirian E; Department of Animal Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
Jamal GA; Faculty of Allied Health Sciences, Kuwait University, Kuwait City, Kuwait. .
Nouroozi M; Department of Animal Science and Food Technology, Agriculture Science and Natural Resources University Khouzestan, Ahwaz, Iran.
Mohammadpour A; Department of Animal Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.
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Źródło :
Immunogenetics [Immunogenetics] 2021 Dec; Vol. 73 (6), pp. 459-477. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19 Vaccines/*immunology
Epitopes, B-Lymphocyte/*immunology
Epitopes, T-Lymphocyte/*immunology
SARS-CoV-2/*immunology
Amino Acid Sequence ; Base Sequence ; COVID-19/prevention & control ; COVID-19 Vaccines/genetics ; COVID-19 Vaccines/metabolism ; Computational Biology ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/genetics ; HLA Antigens/immunology ; Humans ; Immunogenicity, Vaccine ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Weight ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology ; Toll-Like Receptor 7/chemistry ; Toll-Like Receptor 8/chemistry ; Vaccines, Subunit/genetics ; Vaccines, Subunit/immunology ; Vaccines, Subunit/metabolism ; Vaccinology ; Viral Proteins/chemistry ; Viral Proteins/genetics ; Viral Proteins/immunology
Czasopismo naukowe
Tytuł :
Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern.
Autorzy :
Martín-Galiano AJ; Intrahospital Infection Laboratory, National Center of Microbiology, Instituto de Salud Carlos III, Majadahonda, Spain.
Díez-Fuertes F; Acquired Immune Deficiency Syndrome (AIDS) Immunopathology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain.
McConnell MJ; Intrahospital Infection Laboratory, National Center of Microbiology, Instituto de Salud Carlos III, Majadahonda, Spain.
López D; Presentation and Immune Regulation Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Nov 25; Vol. 12, pp. 732693. Date of Electronic Publication: 2021 Nov 25 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19/*immunology
COVID-19 Vaccines/*immunology
Epitopes, B-Lymphocyte/*immunology
Epitopes, T-Lymphocyte/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Alleles ; COVID-19/prevention & control ; COVID-19/virology ; Epitopes, B-Lymphocyte/metabolism ; Epitopes, T-Lymphocyte/metabolism ; Female ; Genes, MHC Class I/genetics ; Genes, MHC Class I/immunology ; Humans ; Immunogenicity, Vaccine/immunology ; Mutation ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/virology ; Vaccination ; Vaccine Efficacy
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe

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