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Wyszukujesz frazę ""ErbB Receptors genetics"" wg kryterium: Temat


Wyświetlanie 1-14 z 14
Tytuł :
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors
Autorzy :
Ayeni, Deborah
Miller, Braden
Kuhlmann, Alexandra
Ho, Ping-Chih
Robles-Oteiza, Camila
Gaefele, Mmaserame
Levy, Stellar
de Miguel, Fernando J.
Perry, Curtis
Guan, Tianxia
Krystal, Gerald
Lockwood, William
Zelterman, Daniel
Homer, Robert
Liu, Zongzhi
Kaech, Susan
Politi, Katerina
Pokaż więcej
Temat :
Research Article
Lung cancer
EGFR
Targeted therapies
Immunotherapies
Mouse models
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
lcsh:RC254-282
Animals
Antineoplastic Agents/therapeutic use
ErbB Receptors/genetics
ErbB Receptors/immunology
Erlotinib Hydrochloride/therapeutic use
Lung Neoplasms/drug therapy
Lung Neoplasms/genetics
Lung Neoplasms/immunology
Mice, Transgenic
Mutation
Oncogenes
Protein Kinase Inhibitors/therapeutic use
T-Lymphocytes/drug effects
T-Lymphocytes/immunology
Tumor Microenvironment/drug effects
Tumor Microenvironment/immunology
Cancer Research
Pharmacology
Oncology
Molecular Medicine
Immunology
Immunology and Allergy
Cancer research
Oncogene
medicine.disease
medicine
Tyrosine kinase
business.industry
business
Erlotinib
medicine.drug
Immune system
Tumor microenvironment
CD40
biology.protein
biology
Epidermal growth factor receptor
respiratory tract diseases
Źródło :
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Journal for immunotherapy of cancer, vol. 7, no. 1, pp. 172
Crossref
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2f07589f052ce53139b4376d5454b5
http://europepmc.org/articles/PMC6617639
Tytuł :
A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine
Autorzy :
Herfs, M.
Roncarati, P.
Koopmansch, B.
Peulen, O.
Bruyere, D.
Lebeau, A.
Hendrick, E.
Hubert, P.
Poncin, A.
Penny, W.
Piazzon, N.
Monnien, F.
Guenat, D.
Mougin, C.
Prétet, J.L.
Vuitton, L.
Segers, K.
Lambert, F.
Bours, V.
de Leval, L.
Valmary-Degano, S.
Quick, C.M.
Crum, C.P.
Delvenne, P.
Pokaż więcej
Temat :
Cancer Research
Oncology
Gastrointestinal cancer
medicine.disease
medicine
Anal gland
business.industry
business
FOXP3
Neuroblastoma RAS viral oncogene homolog
Cancer research
Anal canal adenocarcinoma
KRAS
medicine.disease_cause
Immune system
Anal canal
medicine.anatomical_structure
Article
Adenocarcinoma/genetics
Adenocarcinoma/pathology
Adult
Aged
Aged, 80 and over
Anus Neoplasms/genetics
Anus Neoplasms/pathology
B7-H1 Antigen/genetics
ErbB Receptors/genetics
Female
Gene Expression Regulation, Neoplastic/drug effects
Humans
Inflammation/genetics
Inflammation/pathology
Kaplan-Meier Estimate
Lymphocytes, Tumor-Infiltrating/pathology
Male
Middle Aged
Mutation
Precision Medicine
Prognosis
Programmed Cell Death 1 Receptor/genetics
Tumor Microenvironment/genetics
Źródło :
Crossref
British Journal of Cancer
British journal of cancer, vol. 118, no. 10, pp. 1302-1312
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727b845e13b0a296918d858027e98dab
Tytuł :
Rationale and Study Design of the IRENE-Trial (NVALT-16): A Phase II Trial to Evaluate Iressa Rechallenge in Advanced NSCLC Patients With an Activating EGFR Mutation Who Responded to an EGFR-TKI Used As First-Line or Previous Treatment
Autorzy :
Justine L. Kuiper
Daniëlle A.M. Heideman
Thomas Wurdinger
Katrien Grünberg
Harry J.M. Groen
Egbert F. Smit
Pokaż więcej
Temat :
Cancer Research
Pulmonary and Respiratory Medicine
Oncology
Lung cancer
medicine.disease
medicine
Survival analysis
Response Evaluation Criteria in Solid Tumors
Internal medicine
medicine.medical_specialty
Phases of clinical research
Veristrat
Prospective cohort study
business.industry
business
Gefitinib
medicine.drug
Epidermal growth factor receptor
biology.protein
biology
Immunology
Drug holiday
EGFR
NSCLC
TKI
TKI-resistance
CELL LUNG-CANCER
TYROSINE KINASE INHIBITORS
FACTOR RECEPTOR MUTATIONS
ACQUIRED-RESISTANCE
INITIAL GEFITINIB
OPEN-LABEL
RETROSPECTIVE ANALYSIS
RETREATMENT
CHEMOTHERAPY
ADENOCARCINOMA
Antineoplastic Protocols
Carcinoma, Non-Small-Cell Lung/drug therapy
Clinical Trials as Topic
Drug Resistance, Neoplasm
ErbB Receptors/genetics
Humans
Lung Neoplasms/drug therapy
Mutation/genetics
Prospective Studies
Protein Kinase Inhibitors/administration & dosage
Quinazolines/administration & dosage
Research Design
Survival Analysis
Withholding Treatment
respiratory tract diseases
Źródło :
Crossref
Clinical lung cancer, 16(1), 60-66. CIG MEDIA GROUP, LP
Clinical Lung Cancer, 16(1), 60-66. Elsevier
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3518ca4f76ba2def65ead37923c479ca
https://api.elsevier.com/content/article/PII:S1525730414001508?httpAccept=text/xml
Tytuł :
Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice.:Feasibility in routine clinical practice
Autorzy :
Abdelraouf, Fatma
Sharp, Adam
Maurya, Manisha
Mair, Debbie
Wotherspoon, Andrew
Leary, Alex
Gonzalez de Castro, D.
Bhosle, Jaishree
Nassef, Ayatallah
Gaafar, Taghrid
Popat, Sanjay
Yap, Timothy A.
O'Brien, Mary
Pokaż więcej
Temat :
Aged
Aged, 80 and over
Anaplastic Lymphoma Kinase
DNA Mutational Analysis/methods
ErbB Receptors/genetics
Feasibility Studies
Female
GTP Phosphohydrolases/genetics
Genetic Predisposition to Disease/genetics
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Lung Neoplasms/diagnosis
Male
Membrane Proteins/genetics
Middle Aged
Molecular Diagnostic Techniques/methods
Mutation
Paraffin Embedding/methods
Proto-Oncogene Proteins B-raf/genetics
Proto-Oncogene Proteins c-met/genetics
Proto-Oncogene Proteins p21(ras)/genetics
Receptor Protein-Tyrosine Kinases/genetics
Reproducibility of Results
Sensitivity and Specificity
Small Cell Lung Carcinoma/diagnosis
Tissue Fixation/methods
neoplasms
respiratory tract diseases
Źródło :
Abdelraouf, F, Sharp, A, Maurya, M, Mair, D, Wotherspoon, A, Leary, A, Gonzalez de Castro, D, Bhosle, J, Nassef, A, Gaafar, T, Popat, S, Yap, T A & O'Brien, M 2015, ' Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice. Feasibility in routine clinical practice ', BMC Research Notes, vol. 8, no. 688, pp. 688 . https://doi.org/10.1186/s13104-015-1675-x,">https://doi.org/10.1186/s13104-015-1675-x, https://doi.org/10.1186/s13104-015-1675-x
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=od______2607::02b4065872779babdd603796044fcbb4
https://pure.qub.ac.uk/en/publications/focused-molecular-analysis-of-small-cell-lung-cancer-feasibility-in-routine-clinical-practice(33885afe-3122-4e9e-afa2-38ce51383e8d).html
Tytuł :
PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs
Autorzy :
Anirudh Prahallad
Cor Lieftink
Giovanni Germano
Loredana Vecchione
Stefan M. Willems
Federica Di Nicolantonio
Alberto Bardelli
Bastiaan Evers
Roderick L. Beijersbergen
René Bernards
Guus J. J. E. Heynen
Valentina Gambino
Pokaż więcej
Temat :
Journal Article
Research Support, Non-U.S. Gov't
Research Support
Non-U.S. Gov't
Biochemistry, Genetics and Molecular Biology (all)
lcsh:Biology (General)
lcsh:QH301-705.5
Animals
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Colonic Neoplasms/drug therapy
Drug Resistance, Neoplasm/drug effects
ErbB Receptors/genetics
Gene Expression Regulation, Neoplastic
Genetic Vectors
Genomic Library
High-Throughput Nucleotide Sequencing
Humans
Indoles/pharmacology
Lentivirus/genetics
MAP Kinase Signaling System
Melanoma/drug therapy
Mice
Mice, Inbred NOD
Protein Tyrosine Phosphatase, Non-Receptor Type 11/antagonists & inhibitors
Proto-Oncogene Proteins B-raf/genetics
RNA, Small Interfering/genetics
Sulfonamides/pharmacology
Transduction, Genetic
Vemurafenib
Xenograft Model Antitumor Assays
ras Proteins/genetics
Cell Line
Tumor
Drug Resistance
Neoplasm/drug effects
Gene Expression Regulation
Neoplastic
Inbred NOD
Protein Tyrosine Phosphatase
Non-Receptor Type 11/antagonists & inhibitors
RNA
Small Interfering/genetics
Transduction
Genetic
General Biochemistry, Genetics and Molecular Biology
Genetic screen
medicine.drug
medicine
Melanoma
medicine.disease
Biology
Receptor tyrosine kinase
biology.protein
V600E
Cancer research
PTPN11
Protein tyrosine phosphatase
Colorectal cancer
skin and connective tissue diseases
digestive system diseases
neoplasms
Źródło :
Cell Reports [E], 12(12), 1978. Cell Press
Cell Reports, Vol 12, Iss 12, Pp 1978-1985 (2015)
Cell reports, 12(12), 1978-85. CELL PRESS
Crossref
Opis pliku :
image/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2808d2b6590c5542fe90e2afb7f042
https://dspace.library.uu.nl/handle/1874/333206
Tytuł :
Comparison of next-generation sequencing and mutation-specific platforms in clinical practice
Autorzy :
Remco D. Radersma
John W. J. Hinrichs
Sophia B Rappel
Stefan M. Willems
Carmen M. A. de Voijs
Joyce H. Radersma-van Loon
Michiel J. Moons
W. T. Marja van Blokland
Nicolle Besselink
Marco J. Koudijs
Roel A. de Weger
Pokaż więcej
Temat :
Base Sequence
Carcinoma, Non-Small-Cell Lung/diagnosis
Costs and Cost Analysis
DNA Mutational Analysis/economics
DNA, Neoplasm/chemistry
Education, Medical, Continuing
ErbB Receptors/genetics
Genotype
High-Throughput Nucleotide Sequencing/economics
Humans
Lung Neoplasms/diagnosis
Mutation
Paraffin Embedding
Proto-Oncogene Proteins/genetics
Proto-Oncogene Proteins p21(ras)
Sensitivity and Specificity
Sequence Analysis, DNA
Time Factors
ras Proteins/genetics
Carcinoma
Non-Small-Cell Lung/diagnosis
DNA
Neoplasm/chemistry
Education
Medical
Continuing
Sequence Analysis
General Medicine
KRAS
medicine.disease_cause
medicine
Ion semiconductor sequencing
Genotyping
Genome
Biology
DNA sequencing
Genetics
Sanger sequencing
symbols.namesake
symbols
Roche Diagnostics
Personal genomics
Carcinoma, Non-Small-Cell Lung
DNA Mutational Analysis
DNA, Neoplasm
High-Throughput Nucleotide Sequencing
Lung Neoplasms
Proto-Oncogene Proteins
Receptor, Epidermal Growth Factor
ras Proteins
Comparative Study
Journal Article
Non-Small-Cell Lung
Neoplasm
Receptor
Epidermal Growth Factor
Źródło :
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 143(4), 573-8. Oxford University Press
Crossref
American journal of clinical pathology, 143(4), 573. American Society of Clinical Pathologists
Opis pliku :
image/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5d8afc5ac4bf4d1a3f483d66de4b0c
https://www.rug.nl/research/portal/en/publications/comparison-of-nextgeneration-sequencing-and-mutationspecific-platforms-in-clinical-practice(df04b865-3b5c-428b-8e0f-7ef08a56d357).html
Tytuł :
Utility Of Serum Dna And Pyrosequencing For The Detection Of Egfr Mutations In Non-Small Cell Lung Cancer
Autorzy :
Gülseren Bağcı
Jun Yokota
Arzu Yaren
Reika Iwakawa
Aylin Köseler
Ferda Bir
Aydın Demiray
Hakan Akca
Pokaż więcej
Temat :
Adenocarcinoma/genetics/pathology
Aged
Base Sequence
Carcinoma, Non-Small-Cell Lung/blood/*genetics/pathology
Carcinoma, Squamous Cell/genetics/pathology
DNA, Neoplasm/blood/chemistry/*genetics
ErbB Receptors/*genetics
Female
Humans
Logistic Models
Lung Neoplasms/blood/*genetics/pathology
Male
Middle Aged
Multivariate Analysis
Mutation
Mutation Rate
Mutation, Missense
Neoplasm Staging
Neoplastic Cells, Circulating/metabolism
Sequence Analysis, DNA/methods
Sequence Deletion
EGFR
Mutations
NSCLC
Serum DNA
Turkish
DNA
epidermal growth factor receptor
paraffin
adult
aged
article
cancer staging
controlled study
DNA determination
DNA isolation
DNA sequence
epidermal growth factor receptor gene
female
gene mutation
genetic association
human
human tissue
lung adenocarcinoma
lung non small cell cancer
lung squamous cell carcinoma
major clinical study
male
mutation rate
mutational analysis
point mutation
priority journal
pyrosequencing
single nucleotide polymorphism
tissue section
Adenocarcinoma
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
DNA, Neoplasm
Lung Neoplasms
Neoplastic Cells, Circulating
Receptor, Epidermal Growth Factor
Sequence Analysis, DNA
Cancer Research
Genetics
Molecular Biology
Bioinformatics
Lung cancer
medicine.disease
medicine
COLD-PCR
DNA extraction
Gene
Pyrosequencing
Circulating tumor cell
Sanger sequencing
symbols.namesake
symbols
Cancer research
Biology
respiratory tract diseases
Źródło :
Crossref
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc85ec519edf6d49149ab81c320f063
https://aperta.ulakbim.gov.tr//record/13591
Tytuł :
DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase
Autorzy :
Fabio Cerignoli
Agnès Noël
Tomas Mustelin
Souad Rahmouni
Mathieu Amand
Franck Dequiedt
Lucia Musumeci
Tinatin Zurashvili
Michel Moutschen
Pierre Drion
Charlotte Erpicum
Christine Gilles
Pratibha Singh
Silvia Blacher
Khalid Bajou
Maud Vandereyken
Maud Martin
Pokaż więcej
Temat :
Molecular Medicine
Cancer Research
Oncology
Sciences bio-médicales et agricoles
Animals
Carcinoma, Lewis Lung -- genetics -- metabolism -- pathology
Cell Movement
Cervix Uteri -- blood supply -- metabolism -- pathology
Collagen
Drug Combinations
Dual Specificity Phosphatase 3 -- genetics -- metabolism
ErbB Receptors -- genetics -- metabolism
Extracellular Signal-Regulated MAP Kinases -- genetics -- metabolism
Female
Fibroblast Growth Factors
Gene Expression Regulation
Human Umbilical Vein Endothelial Cells -- cytology -- metabolism
Humans
Laminin
MAP Kinase Kinase 4 -- genetics -- metabolism
Mice
Mice, Knockout
Neovascularization, Pathologic -- prevention & control
Neovascularization, Physiologic -- genetics
Phosphorylation
Protein Kinase C -- genetics -- metabolism
Proteoglycans
Signal Transduction
Matrigel
Dual Specificity Phosphatase 3
Molecular biology
Angiogenesis
Dual-specificity phosphatase
biology.protein
biology
Phosphatase
Downregulation and upregulation
Tube formation
Anatomy (cytology, histology, embryology...) & physiology [Life sciences]
Anatomie (cytologie, histologie, embryologie...) & physiologie [Sciences du vivant]
Research
DUSP3/VHR
Dusp3-knockout mice
Endothelial cells
Źródło :
Molecular cancer, 13
Crossref
DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. (2014).
Molecular Cancer
Opis pliku :
1 full-text file(s): application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582fae43c9d4231f0445ee5b88c21ce2
    Wyświetlanie 1-14 z 14

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