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Tytuł :
[Sickle cell disease].
Autorzy :
Distelmaier L; Klinik für Innere Medizin - Hämatologie, Onkologie und Palliativmedizin, Vivantes Klinikum Neukölln, Rudower Str. 48, 12351, Berlin, Deutschland. .; Klinik für Hämatologie, Universitätsklinikum Essen, Essen, Deutschland. .
Dührsen U; Klinik für Hämatologie, Universitätsklinikum Essen, Essen, Deutschland.
Dickerhoff R; Praxis Prof. Eber, München, Deutschland.
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Transliterated Title :
Sichelzellkrankheit.
Źródło :
Der Internist [Internist (Berl)] 2020 Jul; Vol. 61 (7), pp. 754-758.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anemia, Sickle Cell/*drug therapy
Antineoplastic Agents/*therapeutic use
Erythrocytes/*pathology
Hydroxyurea/*therapeutic use
Erythrocytes, Abnormal ; Humans ; Pain ; Turkey
Czasopismo naukowe
Tytuł :
Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients.
Autorzy :
Thomas T; Department of Pathology & Cell Biology, Columbia University, New York, New York 10032, United States.
Stefanoni D; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Dzieciatkowska M; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Issaian A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Hill RC; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Francis RO; Department of Pathology & Cell Biology, Columbia University, New York, New York 10032, United States.
Hudson KE; Department of Pathology & Cell Biology, Columbia University, New York, New York 10032, United States.
Buehler PW; Department of Pathology, University of Maryland, Baltimore, Maryland 21201, United States.
Zimring JC; Department of Pathology, University of Virginia, Charlottesville, Virginia 22903, United States.
Hod EA; Department of Pathology & Cell Biology, Columbia University, New York, New York 10032, United States.
Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
Spitalnik SL; Department of Pathology & Cell Biology, Columbia University, New York, New York 10032, United States.
D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado 80045, United States.
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Źródło :
Journal of proteome research [J Proteome Res] 2020 Nov 06; Vol. 19 (11), pp. 4455-4469. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural
MeSH Terms :
Coronavirus Infections*/blood
Coronavirus Infections*/pathology
Coronavirus Infections*/physiopathology
Erythrocytes*/chemistry
Erythrocytes*/cytology
Erythrocytes*/pathology
Membrane Lipids*/analysis
Membrane Lipids*/chemistry
Membrane Lipids*/metabolism
Pandemics*
Pneumonia, Viral*/blood
Pneumonia, Viral*/pathology
Pneumonia, Viral*/physiopathology
Betacoronavirus ; Humans ; Lipidomics ; Membrane Proteins/analysis ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Metabolome/physiology ; Models, Molecular ; Proteome/analysis ; Proteome/chemistry ; Proteome/metabolism
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19.
Autorzy :
Venter C; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
Bezuidenhout JA; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
Laubscher GJ; Suite 104, 1 Elsie du Toit Street, Mediclinic Stellenbosch, Stellenbosch 7600, South Africa.
Lourens PJ; Suite 104, 1 Elsie du Toit Street, Mediclinic Stellenbosch, Stellenbosch 7600, South Africa.
Steenkamp J; PathCare Laboratories, PathCare Business Centre, PathCare Park, Neels Bothma Street, N1 City 7460, South Africa.
Kell DB; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Crown St, Liverpool L69 7ZB, UK.; The Novo Nordisk Foundation Centre for Biosustainability, Building 220, Kemitorvet, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Pretorius E; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch 7602, South Africa.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 03; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets/*pathology
Cardiovascular Diseases/*virology
Coronavirus Infections/*blood
Coronavirus Infections/*pathology
Erythrocytes/*pathology
Ferritins/*blood
P-Selectin/*blood
Pneumonia, Viral/*blood
Pneumonia, Viral/*pathology
Betacoronavirus/isolation & purification ; Blood Coagulation/physiology ; Blood Platelets/virology ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/pathology ; Coronavirus Infections/virology ; Erythrocytes/virology ; Female ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/virology ; Thrombosis/pathology ; Thrombosis/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Autologous erythrocytes delivery of berberine hydrochloride with long-acting effect for hypolipidemia treatment.
Autorzy :
Cheng Z; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Liu S; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Wu X; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Raza F; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Li Y; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Yuan W; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Qiu M; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
Su J; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
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Źródło :
Drug delivery [Drug Deliv] 2020 Dec; Vol. 27 (1), pp. 283-291.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Delivery Systems*
Berberine/*administration & dosage
Erythrocytes/*chemistry
Hypolipidemic Agents/*administration & dosage
Animals ; Berberine/pharmacokinetics ; Berberine/pharmacology ; Delayed-Action Preparations ; Drug Carriers/chemistry ; Erythrocytes/metabolism ; Hypolipidemic Agents/pharmacokinetics ; Hypolipidemic Agents/pharmacology ; Male ; Rats ; Rats, Sprague-Dawley ; Time Factors
Czasopismo naukowe
Tytuł :
Standardized Fabrication Method of Human-Derived Emboli with Histologic and Mechanical Quantification for Stroke Research.
Autorzy :
Liu Y; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Reddy AS; Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Cockrum J; Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Ajulufoh MC; School of Medicine, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Zheng Y; Mechanical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA. Electronic address: .
Shih AJ; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Pandey AS; Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: .
Savastano LE; Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA; Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Nov; Vol. 29 (11), pp. 105205. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Blood Platelets/*metabolism
Erythrocytes/*metabolism
Fibrin/*metabolism
Intracranial Embolism/*blood
Plasma/*metabolism
Stroke/*blood
Translational Medical Research/*methods
Biomechanical Phenomena ; Blood Platelets/pathology ; Erythrocytes/pathology ; Humans ; Intracranial Embolism/pathology ; Stress, Mechanical ; Stroke/pathology ; Tensile Strength
Czasopismo naukowe
Tytuł :
Red blood cell tension protects against severe malaria in the Dantu blood group.
Autorzy :
Kariuki SN; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Marin-Menendez A; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Introini V; Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Ravenhill BJ; Cambridge Institute for Medical Research, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Lin YC; Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Macharia A; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Makale J; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Tendwa M; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Nyamu W; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Kotar J; Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Carrasquilla M; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.
Rowe JA; Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Rockett K; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Kwiatkowski D; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, University of Oxford, Oxford, UK.
Weekes MP; Cambridge Institute for Medical Research, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Cicuta P; Cavendish Laboratory, University of Cambridge, Cambridge, UK. .
Williams TN; Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya. .; Institute of Global Health Innovation, Imperial College London, London, UK. .; Department of Infectious Disease, Imperial College London, London, UK. .
Rayner JC; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. .; Cambridge Institute for Medical Research, School of Clinical Medicine, University of Cambridge, Cambridge, UK. .
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Źródło :
Nature [Nature] 2020 Sep; Vol. 585 (7826), pp. 579-583. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Polymorphism, Genetic*
Blood Group Antigens/*genetics
Erythrocytes/*cytology
Erythrocytes/*parasitology
Malaria, Falciparum/*pathology
Malaria, Falciparum/*prevention & control
Plasmodium falciparum/*metabolism
Blood Group Antigens/classification ; Blood Group Antigens/metabolism ; Child ; Erythrocytes/metabolism ; Erythrocytes/pathology ; Female ; Genotype ; Humans ; Kenya ; Ligands ; Male ; Merozoites/metabolism ; Merozoites/pathogenicity ; Microscopy, Video ; Plasmodium falciparum/growth & development ; Plasmodium falciparum/pathogenicity
Czasopismo naukowe
Tytuł :
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.
Autorzy :
Rodrigues DAS; Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Prestes EB; Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Gama AMS; Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Silva LS; Laboratório de Sinalização Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Pinheiro AAS; Laboratório de Sinalização Celular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ribeiro JMC; Section of Vector Biology, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, United States of America.
Campos RMP; Laboratório de Neurobiologia Celular e Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro.
Pimentel-Coelho PM; Laboratório de Neurobiologia Celular e Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro.
De Souza HS; Serviço de Gastroenterologia & Laboratório Multidisciplinar de Pesquisa, Departmento de Medicina Interna, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro and Instituto D'Or para Pesquisa e Educação (IDOR), Rio de Janeiro, Brazil.
Dicko A; Malaria Research & Training Center, Faculty of Medicine, Pharmacy and Dentistry, University of Sciences Techniques and Technologies of Bamako, Bamako, Mali.
Duffy PE; Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Fried M; Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Francischetti IMB; Section of Vector Biology, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, United States of America.
Saraiva EM; Laboratório de Imunobiologia das Leishmanioses, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Paula-Neto HA; Laboratório de Alvos Moleculares, Departamento de Biotecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Bozza MT; Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Aug 14; Vol. 16 (8), pp. e1008230. Date of Electronic Publication: 2020 Aug 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes/*immunology
Extracellular Traps/*immunology
Macrophage Migration-Inhibitory Factors/*metabolism
Malaria/*immunology
Neutrophils/*immunology
Plasmodium/*immunology
Receptors, CXCR4/*metabolism
Animals ; Erythrocytes/metabolism ; Erythrocytes/parasitology ; Extracellular Traps/metabolism ; Extracellular Traps/parasitology ; Humans ; Malaria/metabolism ; Malaria/parasitology ; Malaria/pathology ; Mice ; Mice, Inbred C57BL ; Neutrophils/metabolism ; Neutrophils/parasitology ; Parasitemia/immunology ; Parasitemia/metabolism ; Parasitemia/parasitology ; Parasitemia/pathology
Czasopismo naukowe
Tytuł :
Damage to red blood cells during whole blood storage.
Autorzy :
Oh JY; From the Department of Pathology (J.-Y.O., M.B.M., R.P.P.), Center for Free Radical Biology (J.-Y.O., R.P.P.), Program in Protease and Matrix Biology, Division of Pulmonary, Allergy and Critical Care, Department of Medicine (X.X., J.L., K.G., A.G.), Center for Injury Science, Department of Surgery (J.O.J., J.B.H.), and Department of Anesthesiology (J.-F.-P), University of Alabama at Birmingham, Birmingham, Alabama.
Marques MB
Xu X
Li J
Genschmer K
Gaggar A
Jansen JO
Holcomb JB
Pittet JF
Patel RP
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Źródło :
The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2020 Aug; Vol. 89 (2), pp. 344-350.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Preservation/*adverse effects
Erythrocytes/*pathology
Erythrocytes/*physiology
Blood Preservation/methods ; Carbon Dioxide/blood ; Cell-Derived Microparticles/metabolism ; Citrates ; Erythrocytes/metabolism ; Glucose ; Hemoglobins/metabolism ; Hemolysis ; Humans ; Nitric Oxide/metabolism ; Oxidation-Reduction ; Oxidative Stress ; Oxygen/blood ; Peroxiredoxins/metabolism
Czasopismo naukowe
Tytuł :
Endobronchial ultrasound-guided Transbronchial needle aspiration (EBUS-TBNA) in simulator lesions of pulmonary pathology: a case report of pulmonary Myospherulosis.
Autorzy :
Fernández-Trujillo L; Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Fundación Valle del Lili, Avenida Simón Bolívar. Cra. 98 No.18-49, Tower 6, 4th Floor, Cali, Colombia, 760032. .; Faculty of Health Sciences, Universidad Icesi, Calle 18 # 122-135, Cali, 760032, Colombia. .
Sanchez S; Faculty of Medicine, Department of Internal Medicine, Universidad CES, Cali, Colombia.; Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.
Sangiovanni-Gonzalez S; Clinical Research Center, Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.
Morales EI; Clinical Research Center, Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.; Department of Internal Medicine, Pulmonology Service, Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.
Velásquez M; Faculty of Health Sciences, Universidad Icesi, Calle 18 # 122-135, Cali, 760032, Colombia.; Department of Surgery, Thoracic Surgery Service, Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.
Sua LF; Faculty of Health Sciences, Universidad Icesi, Calle 18 # 122-135, Cali, 760032, Colombia.; Department of Pathology and Laboratory Medicine, Fundación Valle del Lili, Carrera 98 # 18-49, Cali, 760032, Colombia.
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Źródło :
BMC pulmonary medicine [BMC Pulm Med] 2020 Sep 16; Vol. 20 (1), pp. 246. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Endoscopic Ultrasound-Guided Fine Needle Aspiration*
Erythrocytes*
Lipids*
Granuloma/*pathology
Lung Diseases/*pathology
Bronchi ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection.
Autorzy :
Foy BH; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston.; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
Carlson JCT; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston.
Reinertsen E; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Research Laboratory for Electronics, Massachusetts Institute of Technology, Cambridge.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
Padros I Valls R; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
Pallares Lopez R; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
Palanques-Tost E; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
Mow C; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Partners Healthcare Enterprise Research Information Systems, Boston, Massachusetts.
Westover MB; Clinical Data AI Center and Neurology Department, Massachusetts General Hospital, Boston.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston.; Neurology Department, Harvard Medical School, Boston Massachusetts.
Aguirre AD; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston.
Higgins JM; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston.; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts.
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Źródło :
JAMA network open [JAMA Netw Open] 2020 Sep 01; Vol. 3 (9), pp. e2022058. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Erythrocyte Indices*
Erythrocytes*
Hospitalization*
Coronavirus Infections/*mortality
Pneumonia, Viral/*mortality
Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; Biomarkers/blood ; Boston/epidemiology ; Coronavirus ; Coronavirus Infections/blood ; Female ; Hospitals ; Humans ; Male ; Middle Aged ; Pandemics ; Patient Admission ; Pneumonia, Viral/blood ; Proportional Hazards Models ; Retrospective Studies ; Risk Assessment ; Severe Acute Respiratory Syndrome
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention.
Autorzy :
Adderley JD; Centre for Chronic Inflammatory and Infectious and Diseases, Biomedical Sciences Cluster, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, 3083, Australia.
John von Freyend S; Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.
Jackson SA; Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.
Bird MJ; Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.
Burns AL; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, 5005, Australia.
Anar B; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Metcalf T; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Semblat JP; Institut National de la Transfusion Sanguine, Inserm UMR S1134, 75015, Paris, France.
Billker O; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.; Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå University, Umeå, SE-901 87, Sweden.
Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, SA, 5005, Australia.; Burnet Institute, Melbourne, VIC, 3004, Australia.
Doerig C; Centre for Chronic Inflammatory and Infectious and Diseases, Biomedical Sciences Cluster, School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, 3083, Australia. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 11; Vol. 11 (1), pp. 4015. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*/drug effects
Antimalarials/*pharmacology
Erythrocytes/*metabolism
Plasmodium falciparum/*drug effects
Protein Kinase Inhibitors/*pharmacology
Erythrocytes/parasitology ; Host-Parasite Interactions ; Humans ; Inhibitory Concentration 50 ; Life Cycle Stages/drug effects ; Malaria, Falciparum/metabolism ; Malaria, Falciparum/parasitology ; Phosphorylation/drug effects ; Plasmodium falciparum/growth & development ; Plasmodium falciparum/metabolism ; Plasmodium falciparum/physiology ; Protein Array Analysis ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; Proto-Oncogene Proteins B-raf/metabolism ; Proto-Oncogene Proteins c-met/antagonists & inhibitors ; Proto-Oncogene Proteins c-met/metabolism
Czasopismo naukowe
Tytuł :
Active modulation of human erythrocyte mechanics.
Autorzy :
Kuck L; Biorheology Research Laboratory, Griffith University Gold Coast, Southport, Queensland, Australia.
Peart JN; School of Medical Science, Griffith University Gold Coast, Southport, Queensland, Australia.
Simmonds MJ; Biorheology Research Laboratory, Griffith University Gold Coast, Southport, Queensland, Australia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Aug 01; Vol. 319 (2), pp. C250-C257. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes/*metabolism
Ion Channels/*genetics
Mechanotransduction, Cellular/*genetics
Nitric Oxide Synthase/*genetics
Calcium/metabolism ; Cell Membrane/enzymology ; Cell Membrane/genetics ; Enzyme Activation/genetics ; Erythrocytes/enzymology ; Gene Expression Regulation, Enzymologic/genetics ; Humans ; Ion Channels/blood ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism
Czasopismo naukowe
Tytuł :
Do red cell antibodies continue to challenge breastfed babies?
Autorzy :
Webb J; Division of Pediatrics, George Washington University, School of Medicine and Health Sciences, Washington, District of Columbia, United States.; Chronic Transfusion Therapy and Therapeutic Apheresis Program, Children's National Hospital, Washington, District of Columbia, United States.
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Źródło :
Transfusion medicine (Oxford, England) [Transfus Med] 2020 Aug; Vol. 30 (4), pp. 245-246. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Erythrocytes*
Isoantibodies*
Humans ; Infant
Opinia redakcyjna
Tytuł :
Enhanced oxidative stress and damage in glycated erythrocytes.
Autorzy :
Turpin C; Université de La Réunion, INSERM, UMR 1188 Diabète athérothombose Thérapies Réunion Océan Indien (DéTROI), Saint-Denis de La Réunion, France.
Catan A; Centre hospitalier Ouest Réunion, Saint-Paul, France.
Guerin-Dubourg A; Centre hospitalier Ouest Réunion, Saint-Paul, France.
Debussche X; CHU de La Réunion, Service d'endocrinologie, Saint Denis, France.; Centre d'Investigations Cliniques 1410 INSERM, Reunion University Hospital, Saint-Pierre, Réunion, France.
Bravo SB; Proteomic Unit and Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), SERGAS, Santiago de Compostela, CIBERCV, Madrid, Spain.
Álvarez E; Proteomic Unit and Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela (CHUS), SERGAS, Santiago de Compostela, CIBERCV, Madrid, Spain.
Van Den Elsen J; Department of Biology and Biochemistry, University of Bath, Claverton Down, United Kingdom.
Meilhac O; Université de La Réunion, INSERM, UMR 1188 Diabète athérothombose Thérapies Réunion Océan Indien (DéTROI), Saint-Denis de La Réunion, France.; Centre hospitalier universitaire de La Réunion, Saint Denis, France.
Rondeau P; Université de La Réunion, INSERM, UMR 1188 Diabète athérothombose Thérapies Réunion Océan Indien (DéTROI), Saint-Denis de La Réunion, France.
Bourdon E; Université de La Réunion, INSERM, UMR 1188 Diabète athérothombose Thérapies Réunion Océan Indien (DéTROI), Saint-Denis de La Réunion, France.
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Źródło :
PloS one [PLoS One] 2020 Jul 06; Vol. 15 (7), pp. e0235335. Date of Electronic Publication: 2020 Jul 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*blood
Erythrocytes/*pathology
Glycation End Products, Advanced/*metabolism
Reactive Oxygen Species/*metabolism
Blood Glucose/metabolism ; Cell Line ; Coculture Techniques ; Diabetes Mellitus, Type 2/pathology ; Endothelial Cells ; Eryptosis ; Erythrocyte Deformability ; Erythrocytes/metabolism ; Glycated Hemoglobin A/analysis ; Healthy Volunteers ; Hemolysis ; Humans ; Oxidative Stress ; Primary Cell Culture
Czasopismo naukowe
Tytuł :
Elastic hysteresis loop acts as cell deformability in erythrocyte aging.
Autorzy :
Tang F; Key Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, Chongqing, PR China; Immune Cells and Antibody Engineering Research Center of Guizhou Province, Guizhou Medica University, Guizhou, PR China; Key Laboratory of Biology and Medical Engineering, Guizhou Medical University, Guizhou, PR China.
Chen D; Key Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, Chongqing, PR China.
Zhang S; Immune Cells and Antibody Engineering Research Center of Guizhou Province, Guizhou Medica University, Guizhou, PR China.
Hu W; School of Basic Medical Science, Guizhou Medical University, Guizhou, PR China.
Chen J; Immune Cells and Antibody Engineering Research Center of Guizhou Province, Guizhou Medica University, Guizhou, PR China.
Zhou H; Key Laboratory of Biology and Medical Engineering, Guizhou Medical University, Guizhou, PR China.
Zeng Z; School of Basic Medical Science, Guizhou Medical University, Guizhou, PR China. Electronic address: .
Wang X; Key Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, Chongqing, PR China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Jul 01; Vol. 1862 (7), pp. 183309. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocyte Aging/*physiology
Erythrocyte Deformability/*physiology
Erythrocyte Membrane/*ultrastructure
Erythrocytes/*ultrastructure
Erythrocyte Membrane/chemistry ; Erythrocytes/physiology ; Humans ; Microscopy, Atomic Force
Czasopismo naukowe
Tytuł :
H 2 S-stimulated bioenergetics in chicken erythrocytes and the underlying mechanism.
Autorzy :
Jin Z; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; School of Life Science, Shanxi University, Taiyuan, People's Republic of China.
Zhang Q; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; College of Environment and Resources, Shanxi University, Taiyuan, People's Republic of China.
Wondimu E; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.
Verma R; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.
Fu M; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; School of Human Kinetics, Laurentian University, Sudbury, Ontario, Canada.
Shuang T; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.
Arif HM; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; Department of Biology, York University, Toronto, Ontario, Canada.
Wu L; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; School of Human Kinetics, Laurentian University, Sudbury, Ontario, Canada.; Health Sciences North Research Institute, Sudbury, Ontario, Canada.
Wang R; Cardiovascular and Metabolic Research Unit, Laurentian University, Sudbury, Ontario, Canada.; Department of Biology, York University, Toronto, Ontario, Canada.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2020 Jul 01; Vol. 319 (1), pp. R69-R78. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism/*drug effects
Erythrocytes/*metabolism
Hydrogen Sulfide/*pharmacology
Adenosine Triphosphate/blood ; Animals ; Chickens ; Electron Transport/drug effects ; Erythrocytes/drug effects ; Female ; Glucose/pharmacology ; Glutamine/pharmacology ; Hypoxia/metabolism ; Mitochondria/drug effects ; Mitochondria/metabolism ; Succinic Acid/pharmacology ; Sulfurtransferases/metabolism
Czasopismo naukowe
Tytuł :
Enhancement of the blood-circulation time and performance of nanomedicines via the forced clearance of erythrocytes.
Autorzy :
Nikitin MP; Moscow Institute of Physics and Technology, Moscow, Russia. .
Zelepukin IV; Moscow Institute of Physics and Technology, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Shipunova VO; Moscow Institute of Physics and Technology, Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Sokolov IL; Moscow Institute of Physics and Technology, Moscow, Russia.
Deyev SM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Nikitin PI; Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia.
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Źródło :
Nature biomedical engineering [Nat Biomed Eng] 2020 Jul; Vol. 4 (7), pp. 717-731. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes*/immunology
Blood Circulation/*physiology
Drug Carriers/*pharmacology
Nanomedicine/*methods
Animals ; Antibodies ; CD4-Positive T-Lymphocytes ; Cytokines/metabolism ; Doxorubicin/analogs & derivatives ; Female ; Half-Life ; Heterografts ; Liposomes ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Nude ; Nanoparticles/administration & dosage ; Polyethylene Glycols ; Rats ; Rats, Wistar ; Sepsis/drug therapy
Czasopismo naukowe
Tytuł :
Sickling-suppressive effects of chrysin may be associated with sequestration of deoxy-haemoglobin, 2,3-bisphosphoglycerate mutase, alteration of redox homeostasis and functional chemistry of sickle erythrocytes.
Autorzy :
Muhammad A; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Waziri AD; Department of Haematology, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.
Forcados GE; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Sanusi B; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Sani H; Department of Medicine, Kaduna State University, Kaduna State, Nigeria.
Malami I; Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Ethnopharmacy, Usmanu Danfodiyo University, Sokoto, Nigeria.
Abubakar IB; Faculty of Life Sciences, Department of Biochemistry, Kebbi State University of Science and Technology, Aliero, Kebbi State, Nigeria.
Muhammad A; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Muhammad RA; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Mohammed HA; Faculty of Life Sciences, Department of Biochemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
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Źródło :
Human & experimental toxicology [Hum Exp Toxicol] 2020 Apr; Vol. 39 (4), pp. 537-546. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article
MeSH Terms :
Anemia, Sickle Cell/*blood
Antisickling Agents/*pharmacology
Bisphosphoglycerate Mutase/*metabolism
Erythrocytes/*drug effects
Flavonoids/*pharmacology
Hemoglobin, Sickle/*metabolism
Adult ; Biomarkers/blood ; Computer Simulation ; Erythrocytes/chemistry ; Erythrocytes/metabolism ; Homeostasis/drug effects ; Humans ; Molecular Docking Simulation ; Osmotic Fragility/drug effects ; Oxidation-Reduction ; Protein Binding ; Young Adult
Czasopismo naukowe
Tytuł :
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.
Autorzy :
Giannangelo C; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Siddiqui G; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
De Paoli A; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Anderson BM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Edgington-Mitchell LE; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.; Department of Maxillofacial Surgery, College of Dentistry, New York University, New York, New York, United States of America.
Charman SA; Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Creek DJ; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 26; Vol. 16 (6), pp. e1008485. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes*/metabolism
Erythrocytes*/parasitology
Adamantane/*analogs & derivatives
Antimalarials/*pharmacology
Hemoglobins/*metabolism
Heterocyclic Compounds, 1-Ring/*pharmacology
Peroxides/*pharmacology
Plasmodium falciparum/*metabolism
Spiro Compounds/*pharmacology
Adamantane/pharmacology ; Hemoglobins/genetics ; Heterocyclic Compounds/chemistry ; Heterocyclic Compounds/pharmacology ; Humans ; Plasmodium falciparum/genetics ; Proteomics
Czasopismo naukowe

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