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Tytuł :
Endogenous aldehyde accumulation generates genotoxicity and exhaled biomarkers in esophageal adenocarcinoma.
Autorzy :
Antonowicz S; Department of Surgery and Cancer, Imperial College London, London, UK.
Bodai Z; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Wiggins T; Department of Surgery and Cancer, Imperial College London, London, UK.
Markar SR; Department of Surgery and Cancer, Imperial College London, London, UK.
Boshier PR; Department of Surgery and Cancer, Imperial College London, London, UK.
Goh YM; Department of Surgery and Cancer, Imperial College London, London, UK.
Adam ME; Department of Surgery and Cancer, Imperial College London, London, UK.
Lu H; Department of Surgery and Cancer, Imperial College London, London, UK.
Kudo H; Department of Surgery and Cancer, Imperial College London, London, UK.; Centre for Pathology, Imperial College London, London, UK.
Rosini F; Centre for Pathology, Imperial College London, London, UK.
Goldin R; Centre for Pathology, Imperial College London, London, UK.
Moralli D; Chromosome Dynamics Core, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Green CM; Chromosome Dynamics Core, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Peters CJ; Department of Surgery and Cancer, Imperial College London, London, UK.
Habib N; Department of Surgery and Cancer, Imperial College London, London, UK.
Gabra H; Department of Surgery and Cancer, Imperial College London, London, UK.
Fitzgerald RC; MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK.
Takats Z; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Hanna GB; Department of Surgery and Cancer, Imperial College London, London, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 05; Vol. 12 (1), pp. 1454. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Adenocarcinoma/*diagnosis
Adenocarcinoma/*metabolism
Aldehydes/*metabolism
Aldehydes/*toxicity
DNA Damage/*drug effects
Esophageal Neoplasms/*diagnosis
Esophageal Neoplasms/*metabolism
Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Aldehyde Dehydrogenase/metabolism ; Aldehyde Oxidoreductases/genetics ; Aldehyde Oxidoreductases/metabolism ; DNA Adducts ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/pathology ; Esophagus ; Genes, p53/genetics ; Humans ; Metformin
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Concurrent Chemoradiotherapy With Docetaxel, Cisplatin, and 5-Fluorouracil (DCF-RT) vs . Cisplatin and 5-Fluorouracil (CF-RT) for Patients With Unresectable Locally Advanced Esophageal Cancer in a Real-world Clinical Setting.
Autorzy :
Sakai M; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Sohda M; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan; .
Saito H; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Nakazawa N; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Ubukata Y; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Kuriyama K; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Hara K; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Sano A; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Ogawa H; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Yokobori T; Initiative for Advanced Research, Gunma University, Maebashi, Japan.
Murata K; Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Noda SE; Department of Radiation Oncology, Saitama Medical University International Medical Center, Kawagoe, Japan.
Ohno T; Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Shirabe K; Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
Saeki H; Division of Gastroenterological Surgery, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 2141-2145.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Chemoradiotherapy*/adverse effects
Chemoradiotherapy*/methods
Cisplatin/*administration & dosage
Docetaxel/*administration & dosage
Esophageal Neoplasms/*therapy
Fluorouracil/*administration & dosage
Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cisplatin/adverse effects ; Disease Progression ; Docetaxel/adverse effects ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Female ; Fluorouracil/adverse effects ; Humans ; Japan/epidemiology ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Invasiveness ; Radiotherapy, Intensity-Modulated/methods ; Retrospective Studies ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
GATA binding protein 6 (GATA6) is co-amplified with PIK3CA in patients with esophageal adenocarcinoma and is linked to neoadjuvant therapy.
Autorzy :
Plum PS; Department of General, Visceral, Cancer, and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany. .; Gastrointestinal Cancer Group Cologne (GCGC), Cologne, Germany. .; Else Kröner Forschungskolleg Cologne 'Clonal Evolution in Cancer', Cologne, Germany. .; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany. .
Löser H; Gastrointestinal Cancer Group Cologne (GCGC), Cologne, Germany.; Institute of Pathology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Zander T; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.; Department of Internal Medicine I, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Essakly A; Institute of Pathology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Bruns CJ; Department of General, Visceral, Cancer, and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.
Hillmer AM; Institute of Pathology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Alakus H; Department of General, Visceral, Cancer, and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.
Schröder W; Department of General, Visceral, Cancer, and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.
Büttner R; Institute of Pathology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Gebauer F; Department of General, Visceral, Cancer, and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.
Quaas A; Gastrointestinal Cancer Group Cologne (GCGC), Cologne, Germany.; Centre for Integrated Oncology (CIO), Cologne Bonn, Cologne, Germany.; Institute of Pathology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
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Źródło :
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2021 Apr; Vol. 147 (4), pp. 1031-1040. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Amplification*
Adenocarcinoma/*pathology
Class I Phosphatidylinositol 3-Kinases/*genetics
Esophageal Neoplasms/*pathology
GATA6 Transcription Factor/*genetics
Neoadjuvant Therapy/*mortality
Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Adult ; Aged ; Aged, 80 and over ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/genetics ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Survival Rate
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Perineural invasion predicts for locoregional failure in patients with oesophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy.
Autorzy :
Patel AK; Department of Radiation Oncology, Ohio State University James Cancer Hospital, Columbus, Ohio, USA.
Pan X; Department of Biomedical Informatics, Ohio State University College of Medicine, Columbus, Ohio, USA.
Vila DM; Department of Radiation Oncology, Ohio State University James Cancer Hospital, Columbus, Ohio, USA.
Frankel WL; Department of Pathology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Chen W; Department of Pathology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Perry KA; Division of General and Gastrointestinal Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Merritt RE; Division of Thoracic Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
D'Souza DM; Division of Thoracic Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Wuthrick EJ; Department of Radiation Oncology, Ohio State University James Cancer Hospital, Columbus, Ohio, USA.
Williams TM; Department of Radiation Oncology, Ohio State University James Cancer Hospital, Columbus, Ohio, USA .
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Źródło :
Journal of clinical pathology [J Clin Pathol] 2021 Apr; Vol. 74 (4), pp. 228-233. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Chemoradiotherapy, Adjuvant*/adverse effects
Chemoradiotherapy, Adjuvant*/mortality
Esophagectomy*/adverse effects
Esophagectomy*/mortality
Neoadjuvant Therapy*/adverse effects
Neoadjuvant Therapy*/mortality
Neoplasm Recurrence, Local*
Adenocarcinoma/*therapy
Esophageal Neoplasms/*therapy
Peripheral Nerves/*pathology
Adenocarcinoma/mortality ; Adenocarcinoma/secondary ; Adult ; Aged ; Disease Progression ; Disease-Free Survival ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Invasiveness ; Neoplasm Staging ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Failure
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Frequency and Implications of Paratracheal Lymph Node Metastases in Resectable Esophageal or Gastroesophageal Junction Adenocarcinoma.
Autorzy :
Harada K; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.
Hwang H; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX.
Wang X; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX.
Abdelhakeem A; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Iwatsuki M; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.
Blum Murphy MA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Maru DM; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Weston B; Department of Gastroenterology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Lee JH; Department of Gastroenterology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Rogers JE; Pharmacy Clinical Programs, The University of Texas MD Anderson Cancer Center, Houston, TX.
Thomas I; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Shanbhag N; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Zhao M; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Bhutani MS; Department of Gastroenterology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Nguyen QN; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Swisher SG; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
Ikoma N; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Badgwell BD; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Hofstetter WL; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
Ajani JA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
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Źródło :
Annals of surgery [Ann Surg] 2021 Apr 01; Vol. 273 (4), pp. 751-757.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Esophagogastric Junction*
Neoplasm Staging*
Adenocarcinoma/*surgery
Esophageal Neoplasms/*surgery
Esophagectomy/*methods
Lymph Node Excision/*methods
Lymph Nodes/*pathology
Adenocarcinoma/diagnosis ; Adenocarcinoma/secondary ; Adult ; Aged ; Aged, 80 and over ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/secondary ; Female ; Follow-Up Studies ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Retrospective Studies ; Survival Rate/trends ; United States/epidemiology ; Young Adult
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
An Analysis of Outcomes After Transition From Open to Minimally Invasive Ivor Lewis Esophagectomy.
Autorzy :
Merritt RE; Division of Thoracic Surgery, The Ohio State University Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio. Electronic address: .
Kneuertz PJ; Division of Thoracic Surgery, The Ohio State University Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio.
D'Souza DM; Division of Thoracic Surgery, The Ohio State University Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio.
Abdel-Rasoul M; Department of Biomedical Informatics, The Ohio State University Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio.
Perry KA; Division of General and Gastrointestinal Surgery, The Ohio State University Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio.
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2021 Apr; Vol. 111 (4), pp. 1174-1181. Date of Electronic Publication: 2020 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
Propensity Score*
Esophageal Neoplasms/*surgery
Esophagectomy/*methods
Minimally Invasive Surgical Procedures/*methods
Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/mortality ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Ohio/epidemiology ; Retrospective Studies ; Survival Rate/trends ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
[Surgical treatment of esophageal cancer-Indicators for quality in diagnostics and treatment].
Autorzy :
Hoeppner J; Klinik für Allgemein- und Viszeralchirurgie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg im Breisgau, Hugstetter Straße 55, 79106, Freiburg, Deutschland. .
Plum PS; Klinik für Allgemein‑, Viszeral‑, Tumor- und Transplantationschirurgie, Universitätsklinikum Köln, Köln, Deutschland.
Buhr H; Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie, Berlin, Deutschland.
Gockel I; Klinik für Viszeral‑, Thorax‑, Transplantations- und Gefäßchirurgie, Universitätsklinikum Leipzig, Leipzig, Deutschland.
Lorenz D; Chirurgische Klinik I, Allgemein‑, Viszeral- und Thoraxchirurgie, Klinikum Darmstadt, Darmstadt, Deutschland.
Ghadimi M; Klinik für Allgemein‑, Viszeral- und Kinderchirurgie, Universitätsmedizin Göttingen, Göttingen, Deutschland.
Bruns C; Klinik für Allgemein‑, Viszeral‑, Tumor- und Transplantationschirurgie, Universitätsklinikum Köln, Köln, Deutschland.
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Transliterated Title :
Chirurgische Therapie des Ösophaguskarzinoms – Qualitätsindikatoren für Diagnostik und Therapie.
Corporate Authors :
Qualitätskommission der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie
Źródło :
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen [Chirurg] 2021 Apr; Vol. 92 (4), pp. 350-360.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Esophageal Neoplasms*/diagnosis
Esophageal Neoplasms*/surgery
Laparoscopy*
Esophagectomy ; Germany ; Humans ; Neoadjuvant Therapy ; Thoracoscopy ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Neoadjuvant chemoradiotherapy improves survival in locally advanced adenocarcinoma of esophagogastric junction compared with neoadjuvant chemotherapy: a propensity score matching analysis.
Autorzy :
Li J; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Zhao Q; Department of General Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Ge X; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Song Y; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Tian Y; Department of General Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Wang S; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Liu M; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Qiao X; Department of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, Hebei, China. .
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Źródło :
BMC surgery [BMC Surg] 2021 Mar 17; Vol. 21 (1), pp. 137. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*therapy
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Chemoradiotherapy/*methods
Esophageal Neoplasms/*therapy
Neoadjuvant Therapy/*methods
Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adult ; Aged ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophagogastric Junction/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Propensity Score ; Survival Rate
Czasopismo naukowe
Tytuł :
RIPK1 contributes to cisplatin-induced apoptosis of esophageal squamous cell carcinoma cells via activation of JNK pathway.
Autorzy :
Zhang Y; Department of Thoracic Surgery, Dingyuan County General Hospital of Chuzhou City in Anhui, Anhui 233200, China.
Du J; Department of Oncology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230036, China.
Duan X; Department of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200123, China. Electronic address: .
Peng W; Department of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200123, China. Electronic address: .
Lv L; Anhui Provincial Cancer Hospital, West Branch of the First Afliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230031, Anhui, China. Electronic address: .
Chen Z; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China. Department of Oncology, Shanghai Medical College, Fudan University, 130 Dong An Road, Shanghai 200032, China. Electronic address: .
Zhang Y; Department of VIP Clinic, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200123, China. Department of Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200123, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119064. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Cisplatin/*pharmacology
Esophageal Neoplasms/*pathology
Esophageal Squamous Cell Carcinoma/*pathology
Gene Expression Regulation, Neoplastic/*drug effects
MAP Kinase Signaling System/*drug effects
Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism
Antineoplastic Agents/pharmacology ; Cell Proliferation ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/metabolism ; Esophageal Squamous Cell Carcinoma/drug therapy ; Esophageal Squamous Cell Carcinoma/metabolism ; Humans ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Renal metastases from esophageal cancer and retroperitoneal lymphoma detected via chromosome duplications identified by fluorescence in situ hybridization in urine exfoliated cells: First 2 case reports.
Autorzy :
Hu Z; Department of Urology, Tongji Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology (HUST), 1095 Jiefang Avenue, Wuhan, China.
Ke C
Shen Y
Zeng X
Yang C
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Mar 12; Vol. 100 (10), pp. e24010.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Esophageal Neoplasms/*pathology
Kidney Neoplasms/*diagnosis
Lymphoma/*pathology
Retroperitoneal Neoplasms/*pathology
Chromosome Duplication ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/genetics ; Esophageal Neoplasms/urine ; Esophagus/diagnostic imaging ; Humans ; In Situ Hybridization, Fluorescence ; Kidney/diagnostic imaging ; Kidney/pathology ; Kidney/surgery ; Kidney Neoplasms/genetics ; Kidney Neoplasms/secondary ; Kidney Neoplasms/urine ; Liquid Biopsy/methods ; Lymph Nodes/diagnostic imaging ; Lymphoma/genetics ; Lymphoma/urine ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Retroperitoneal Neoplasms/genetics ; Retroperitoneal Neoplasms/urine ; Retroperitoneal Space/diagnostic imaging ; Tomography, X-Ray Computed ; Urinalysis/methods
Czasopismo naukowe
Tytuł :
Safety and feasibility of esophagectomy following combined immunotherapy and chemoradiotherapy for esophageal cancer.
Autorzy :
Sihag S; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Ku GY; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Tan KS; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Nussenzweig S; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Wu A; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.
Janjigian YY; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Jones DR; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Molena D; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: .
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Źródło :
The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2021 Mar; Vol. 161 (3), pp. 836-843.e1. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Webcast
MeSH Terms :
Chemoradiotherapy, Adjuvant*/adverse effects
Chemoradiotherapy, Adjuvant*/mortality
Esophagectomy*/adverse effects
Esophagectomy*/mortality
Immunotherapy*/adverse effects
Immunotherapy*/mortality
Neoadjuvant Therapy*/adverse effects
Neoadjuvant Therapy*/mortality
Adenocarcinoma/*therapy
Esophageal Neoplasms/*therapy
Adenocarcinoma/diagnosis ; Adenocarcinoma/mortality ; Aged ; Clinical Trials, Phase I as Topic ; Clinical Trials, Phase II as Topic ; Databases, Factual ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/mortality ; Feasibility Studies ; Female ; Humans ; Male ; Middle Aged ; Patient Readmission ; Patient Safety ; Postoperative Complications/etiology ; Postoperative Complications/mortality ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Tumor budding assessed according to the criteria of the International Tumor Budding Consensus Conference determines prognosis in resected esophageal adenocarcinoma.
Autorzy :
Lohneis P; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany. .
Hieggelke L; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Gebauer F; Faculty of Medicine and University Hospital Cologne, Department of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Ball M; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Bruns C; Faculty of Medicine and University Hospital Cologne, Department of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Büttner R; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Löser H; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
Quaas A; Faculty of Medicine and University Hospital Cologne, Institute of Pathology, University of Cologne, Kerpener Strasse 62, D-50924, Cologne, Germany.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Mar; Vol. 478 (3), pp. 393-400. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Movement*
Adenocarcinoma/*pathology
Esophageal Neoplasms/*pathology
Adenocarcinoma/chemistry ; Adenocarcinoma/mortality ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Esophageal Neoplasms/chemistry ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/surgery ; Esophagectomy ; Female ; Humans ; Immunohistochemistry ; Keratins/analysis ; Male ; Middle Aged ; Neoplasm Invasiveness ; Predictive Value of Tests ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Treatment Outcome
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Impact of Age on Surgical Outcomes for Locally Advanced Esophageal Cancer.
Autorzy :
Farrow NE; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina. Electronic address: .
Raman V; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Jawitz OK; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Voigt SL; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Tong BC; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
Harpole DH Jr; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
D'Amico TA; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2021 Mar; Vol. 111 (3), pp. 996-1003. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neoplasm Staging*
Adenocarcinoma/*surgery
Esophageal Neoplasms/*surgery
Esophagectomy/*methods
Adenocarcinoma/diagnosis ; Adenocarcinoma/mortality ; Age Factors ; Aged ; California/epidemiology ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/mortality ; Female ; Humans ; Male ; Middle Aged ; Risk Factors ; Survival Rate/trends ; Treatment Outcome
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
High Systemic Immune-Inflammation Index is an Adverse Prognostic Factor for Patients With Gastroesophageal Adenocarcinoma.
Autorzy :
Jomrich G; Department of Surgery, Medical University of Vienna, and Gastroesophageal Tumor Unit, Comprehensive Cancer Center (CCC), Vienna, Austria.
Paireder M; Department of Surgery, Medical University of Vienna, and Gastroesophageal Tumor Unit, Comprehensive Cancer Center (CCC), Vienna, Austria.
Kristo I; Department of Surgery, Medical University of Vienna, and Gastroesophageal Tumor Unit, Comprehensive Cancer Center (CCC), Vienna, Austria.
Baierl A; Department of Statistics and Operations Research, University of Vienna, Vienna, Austria.
Ilhan-Mutlu A; Department of Medicine 1, Medical University of Vienna, Vienna, Austria.; Comprehensive Cancer Center (CCC), Vienna, Austria.
Preusser M; Department of Medicine 1, Medical University of Vienna, Vienna, Austria.; Comprehensive Cancer Center (CCC), Vienna, Austria.
Asari R; Department of Surgery, Medical University of Vienna, and Gastroesophageal Tumor Unit, Comprehensive Cancer Center (CCC), Vienna, Austria.
Schoppmann SF; Department of Surgery, Medical University of Vienna, and Gastroesophageal Tumor Unit, Comprehensive Cancer Center (CCC), Vienna, Austria.
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Źródło :
Annals of surgery [Ann Surg] 2021 Mar 01; Vol. 273 (3), pp. 532-541.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*immunology
Esophageal Neoplasms/*immunology
Inflammation/*immunology
Stomach Neoplasms/*immunology
Adenocarcinoma/mortality ; Adenocarcinoma/surgery ; Adult ; Aged ; Austria ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/surgery ; Esophagectomy ; Female ; Humans ; Male ; Middle Aged ; Neoadjuvant Therapy ; Prognosis ; Prospective Studies ; Stomach Neoplasms/mortality ; Stomach Neoplasms/surgery ; Survival Rate
Czasopismo naukowe
Tytuł :
Predictive factors of recurrence in adenocarcinoma of the esophagogastric junction in the multimodal era.
Autorzy :
Takeda FR; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil. Electronic address: .
Kodama Pertille Ramos MF; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Pereira MA; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Muniz RR; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Tustumi F; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Biachi de Castria T; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Aissar Sallum RA; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Zilberstein B; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Junior UR; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
Cecconello I; Department of Gastroenterology, Digestive Surgery Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil.
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Źródło :
American journal of surgery [Am J Surg] 2021 Mar; Vol. 221 (3), pp. 631-636. Date of Electronic Publication: 2020 Aug 22.
Typ publikacji :
Journal Article
MeSH Terms :
Esophagogastric Junction*
Adenocarcinoma/*pathology
Adenocarcinoma/*therapy
Esophageal Neoplasms/*pathology
Esophageal Neoplasms/*therapy
Neoplasm Recurrence, Local/*etiology
Adenocarcinoma/mortality ; Aged ; Combined Modality Therapy ; Disease-Free Survival ; Esophageal Neoplasms/mortality ; Esophagectomy ; Female ; Gastrectomy ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/diagnosis ; Neoplasm Recurrence, Local/mortality ; Neoplasm Staging ; Retrospective Studies ; Risk Factors ; Survival Rate
Czasopismo naukowe
Tytuł :
SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.
Autorzy :
Horton RK; Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.
Ahadi M; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital.; Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, St. Leonards.; Department of Anatomical Pathology, Univeristy of Sydney, Sydney, NSW, Australia.
Gill AJ; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital.; Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, St. Leonards.; Department of Anatomical Pathology, Univeristy of Sydney, Sydney, NSW, Australia.
Said S; Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.
Chen ZE; Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.
Bakhshwin A; Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.
Nichols M; Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.
Goldblum JR; Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.
Graham RP; Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.
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Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2021 Mar 01; Vol. 45 (3), pp. 414-420.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Biomarkers, Tumor/*deficiency
Carcinoma/*enzymology
DNA Helicases/*deficiency
Esophageal Neoplasms/*enzymology
Esophagogastric Junction/*enzymology
Nuclear Proteins/*deficiency
Stomach Neoplasms/*enzymology
Transcription Factors/*deficiency
Aged ; Aged, 80 and over ; Carcinoma/mortality ; Carcinoma/pathology ; Carcinoma/surgery ; Cell Differentiation ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagogastric Junction/pathology ; Esophagogastric Junction/surgery ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; New South Wales ; Prognosis ; Retrospective Studies ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Time Factors ; United States
Czasopismo naukowe
Tytuł :
MTA2 promotes the metastasis of esophageal squamous cell carcinoma via EIF4E-Twist feedback loop.
Autorzy :
Dai SL; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Wei SS; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Zhang C; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Li XY; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Liu YP; Department of Pathology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Ma M; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Lv HL; Department of Fifth Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Zhang Z; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Zhao LM; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Shan BE; Research Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Mar; Vol. 112 (3), pp. 1060-1074. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms/*genetics
Esophageal Squamous Cell Carcinoma/*genetics
Eukaryotic Initiation Factor-4E/*metabolism
Histone Deacetylases/*metabolism
Nuclear Proteins/*genetics
Repressor Proteins/*metabolism
Twist-Related Protein 1/*genetics
Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition/genetics ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma/mortality ; Esophageal Squamous Cell Carcinoma/secondary ; Esophageal Squamous Cell Carcinoma/surgery ; Esophagectomy ; Esophagus/pathology ; Esophagus/surgery ; Eukaryotic Initiation Factor-4E/genetics ; Feedback, Physiological ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Histone Deacetylases/genetics ; Humans ; Kaplan-Meier Estimate ; Male ; Mice ; Middle Aged ; Nuclear Proteins/metabolism ; Prognosis ; Promoter Regions, Genetic ; Repressor Proteins/genetics ; Twist-Related Protein 1/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Predicting Lymph Node Metastasis Using Computed Tomography Radiomics Analysis in Patients With Resectable Esophageal Squamous Cell Carcinoma.
Autorzy :
Zhao B; From the Department of Radiology, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital and Institute, Haidian District, Beijing, China.
Zhu HT
Li XT
Shi YJ
Cao K
Sun YS
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Źródło :
Journal of computer assisted tomography [J Comput Assist Tomogr] 2021 Mar-Apr 01; Vol. 45 (2), pp. 323-329.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms*/diagnostic imaging
Esophageal Neoplasms*/epidemiology
Esophageal Neoplasms*/pathology
Esophageal Squamous Cell Carcinoma*/diagnostic imaging
Esophageal Squamous Cell Carcinoma*/epidemiology
Esophageal Squamous Cell Carcinoma*/pathology
Tomography, X-Ray Computed*
Lymph Nodes/*diagnostic imaging
Lymphatic Metastasis/*diagnostic imaging
Aged ; Female ; Humans ; Male ; Middle Aged ; Nomograms ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Esophageal Squamous Cell Carcinoma After Radiofrequency Catheter Ablation Thermal Injury.
Autorzy :
Grubic AD; Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Ayazi S; Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Zaidi AH; Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Schwameis K; Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, Pennsylvania.
Jobe BA; Esophageal and Lung Institute, Allegheny Health Network, Pittsburgh, Pennsylvania. Electronic address: .
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2021 Mar; Vol. 111 (3), pp. e185-e187. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Case Reports
MeSH Terms :
Postoperative Complications*
Atrial Fibrillation/*surgery
Burns/*complications
Catheter Ablation/*adverse effects
Esophageal Neoplasms/*etiology
Esophageal Squamous Cell Carcinoma/*etiology
Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma/diagnosis ; Esophageal Squamous Cell Carcinoma/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Tomography, X-Ray Computed
Raport
Tytuł :
Nomograms for predicting overall and recurrence-free survival after trimodality therapy for esophageal adenocarcinoma.
Autorzy :
Merritt RE; Thoracic Surgery Division, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Abdel-Rasoul M; Department of Biomedical Informatics, Center for Biostatistics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
Souza DM; Thoracic Surgery Division, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Kneuertz PJ; Thoracic Surgery Division, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
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Źródło :
Journal of surgical oncology [J Surg Oncol] 2021 Mar; Vol. 123 (4), pp. 881-890. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Nomograms*
Adenocarcinoma/*mortality
Esophageal Neoplasms/*mortality
Esophagectomy/*mortality
Neoadjuvant Therapy/*mortality
Neoplasm Recurrence, Local/*mortality
Adenocarcinoma/pathology ; Adenocarcinoma/therapy ; Adult ; Aged ; Aged, 80 and over ; Combined Modality Therapy ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/therapy ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/therapy ; Prognosis ; Retrospective Studies ; Survival Rate ; Young Adult
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe

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