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Wyszukujesz frazę ""Estrogen Receptor alpha"" wg kryterium: Temat


Tytuł :
Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway.
Autorzy :
Hwang ST; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Yang MH; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Republic of Korea.
Baek SH; College of Korean Medicine, Dongguk University, 32 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 10326, Republic of Korea.
Um JY; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.
Ahn KS; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118594. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacology
Breast Neoplasms/*drug therapy
Estrogen Receptor alpha/*metabolism
Isoflavones/*pharmacology
Apoptosis/drug effects ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Estrogen Receptor alpha/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; MCF-7 Cells ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERα action and associates with the sensitivity of antiestrogen in breast cancer.
Autorzy :
Sun G; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Wang C; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Wang S; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Sun H; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Zeng K; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Zou R; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Lin L; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Liu W; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Sun N; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Song H; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Liu W; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Zhou T; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.
Jin F; Department of Breast Surgery, the First Affiliated Hospital of China Medical University, Shenyang City 110001, Liaoning Province, China.
Shan Z; Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, ShenyangCity110001, Liaoning Province, China.
Zhao Y; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, School of Life Sciences, China Medical University, Shenyang City 110122, Liaoning Province, China.; Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, ShenyangCity110001, Liaoning Province, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 10768-10784.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Histone Code*
Biomarkers, Tumor/*genetics
Breast Neoplasms/*genetics
DNA-Binding Proteins/*genetics
Estrogen Receptor alpha/*genetics
Animals ; Antineoplastic Agents, Hormonal/pharmacology ; Antineoplastic Agents, Hormonal/therapeutic use ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; DNA-Binding Proteins/metabolism ; Estrogen Receptor Modulators/pharmacology ; Estrogen Receptor Modulators/therapeutic use ; Estrogen Receptor alpha/antagonists & inhibitors ; Estrogen Receptor alpha/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; MCF-7 Cells ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Response Elements
Czasopismo naukowe
Tytuł :
Dioxybenzone triggers enhanced estrogenic effect via metabolic activation: in silico, in vitro and in vivo investigation.
Autorzy :
Zhan T; Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, 310058, Hangzhou, China.
Zhang L; Computational Biological Center, IBM Thomas J. Watson Research Center, Yorktown Heights, NY, United States.
Cui S; Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, 310058, Hangzhou, China.
Liu W; Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, 310058, Hangzhou, China.
Zhou R; Institute of Quantitative Biology and College of Life Sciences, Zhejiang University, 310058, Hangzhou, China; Department of Chemistry, Columbia University, New York, NY, United States.
Zhuang S; Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, 310058, Hangzhou, China. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2021 Jan 01; Vol. 268 (Pt B), pp. 115766. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Estrogen Receptor alpha*/metabolism
Estrogens*
Activation, Metabolic ; Animals ; Benzophenones/toxicity ; Computer Simulation ; Female ; Rats
Czasopismo naukowe
Tytuł :
How Targeting Fat Cells' Estrogen Receptors Could Fight Obesity.
Autorzy :
Hampton T
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Źródło :
JAMA [JAMA] 2020 Dec 01; Vol. 324 (21), pp. 2146.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression*
Adipocytes/*metabolism
Estrogen Receptor alpha/*genetics
Obesity/*metabolism
Receptors, Estrogen/*metabolism
Animals ; Estrogen Receptor alpha/metabolism ; Female ; Humans ; Male ; Mice ; Mitochondria/metabolism ; Obesity/genetics
Czasopismo naukowe
Tytuł :
MST2 silencing induces apoptosis and inhibits tumor growth for estrogen receptor alpha-positive MCF-7 breast cancer.
Autorzy :
Park J; Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Kwangjin-gu, Seoul 05006, South Korea.
Kim GH; Department of Immunology, School of Medicine, Konkuk University, Chungju 380-701, South Korea.
Lee J; Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Kwangjin-gu, Seoul 05006, South Korea.
Phuong BTC; Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Kwangjin-gu, Seoul 05006, South Korea.
Kong B; Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Kwangjin-gu, Seoul 05006, South Korea.
Won JE; Department of Immunology, School of Medicine, Konkuk University, Chungju 380-701, South Korea.
Won GW; Department of Biochemistry, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 28644, South Korea.
Lee YH; Department of Biochemistry, College of Medicine, Chungbuk National University, Cheongju, Chungbuk 28644, South Korea.
Han HD; Department of Immunology, School of Medicine, Konkuk University, Chungju 380-701, South Korea. Electronic address: .
Lee Y; Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Kwangjin-gu, Seoul 05006, South Korea. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 Dec 01; Vol. 408, pp. 115257. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Estrogen Receptor alpha*
Mammary Neoplasms, Experimental/*genetics
Protein-Serine-Threonine Kinases/*genetics
Animals ; Apoptosis ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Female ; Gene Silencing ; Humans ; Mammary Neoplasms, Experimental/metabolism ; Mammary Neoplasms, Experimental/pathology ; Mice, Inbred BALB C ; Mice, Nude ; Protein-Serine-Threonine Kinases/metabolism ; RNA, Small Interfering
Czasopismo naukowe
Tytuł :
Accurate assessment of estrogen receptor profiles in non-functioning pituitary adenomas using RT-digital PCR and immunohistochemistry.
Autorzy :
Hattori Y; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Department of Neurological Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan. Electronic address: .
Ishii H; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Tahara S; Department of Neurological Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Morita A; Department of Neurological Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Ozawa H; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118416. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Adenoma/*pathology
Biomarkers, Tumor/*metabolism
Estrogen Receptor alpha/*metabolism
Estrogen Receptor beta/*metabolism
Pituitary Neoplasms/*pathology
Adenoma/genetics ; Adenoma/metabolism ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Estrogen Receptor alpha/genetics ; Estrogen Receptor beta/genetics ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Pituitary Neoplasms/genetics ; Pituitary Neoplasms/metabolism ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Important roles of estrogen receptor alpha in tumor progression and anti-estrogen therapy of pancreatic ductal adenocarcinoma.
Autorzy :
Xue J; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Yao Y; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Yao Q; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Tian X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Feng Y; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Su H; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Kong D; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China.
Cui C; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Yan L; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Hao C; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address: .
Zhou T; Department of Pharmaceutics, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100191, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118302. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma/*drug therapy
Carcinoma, Pancreatic Ductal/*drug therapy
Estrogen Receptor Modulators/*therapeutic use
Estrogen Receptor alpha/*physiology
Pancreatic Neoplasms/*drug therapy
Adenocarcinoma/pathology ; Adenocarcinoma/physiopathology ; Animals ; Antineoplastic Combined Chemotherapy Protocols ; Carcinoma, Pancreatic Ductal/pathology ; Carcinoma, Pancreatic Ductal/physiopathology ; Cell Line, Tumor ; Deoxycytidine/administration & dosage ; Deoxycytidine/analogs & derivatives ; Estradiol/pharmacology ; Estrogen Receptor alpha/genetics ; Female ; Gene Expression ; Gene Knockout Techniques ; Humans ; Letrozole/administration & dosage ; Leuprolide/administration & dosage ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/physiopathology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Quercetin regulates ERα mediated differentiation of BMSCs through circular RNA.
Autorzy :
Li X; College of Traditional Chinese Medicine, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China.
Chen R; College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China.
Lei X; College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China.
Wang P; Department of the First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, Guangdong 510630, PR China.
Zhu X; College of Traditional Chinese Medicine, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China; Department of the First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, Guangdong 510630, PR China.
Zhang R; College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China. Electronic address: .
Yang L; College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, PR China. Electronic address: .
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Źródło :
Gene [Gene] 2021 Feb 15; Vol. 769, pp. 145172. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Estrogen Receptor alpha/*physiology
Mesenchymal Stem Cells/*drug effects
Osteogenesis/*drug effects
Phytoestrogens/*pharmacology
Quercetin/*pharmacology
RNA, Circular/*physiology
Adipogenesis/physiology ; Antioxidants/pharmacology ; Cell Survival ; Cells, Cultured ; Computational Biology ; Estrogen Receptor alpha/genetics ; Gene Expression Regulation ; Humans ; Mesenchymal Stem Cells/physiology ; Osteogenesis/physiology ; Quercetin/physiology ; RNA, Circular/genetics
Czasopismo naukowe
Tytuł :
Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility.
Autorzy :
Adlanmerini M; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Fébrissy C; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Zahreddine R; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Vessières E; Institut National de la Santé et de la Recherche Médicale U1083, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 46 015, Université d'Angers, France (E.V., J.F., A.-L.G., D.H.).
Buscato M; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Solinhac R; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Favre J; Institut National de la Santé et de la Recherche Médicale U1083, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 46 015, Université d'Angers, France (E.V., J.F., A.-L.G., D.H.).
Anquetil T; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Guihot AL; Institut National de la Santé et de la Recherche Médicale U1083, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 46 015, Université d'Angers, France (E.V., J.F., A.-L.G., D.H.).
Boudou F; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Raymond-Letron I; Institut National Polytechnique, École Nationale Vétérinaire de Toulouse, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Service 006 (I.R.-L.), Université de Toulouse, France.
Chambon P; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Collège de France, Université de Strasbourg, Illkirch, France (P.C.).
Gourdy P; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Ohlsson C; Centre for Bone and Arthritis Research Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Sweden (C.O.).
Laurell H; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Fontaine C; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Metivier R; CNRS, Université de Rennes, IGDR (Institut de Génétique De Rennes) - UMR 6290, France (R.M.).
Le Romancer M; Inserm U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, France (M.L.R.).
Henrion D; Institut National de la Santé et de la Recherche Médicale U1083, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 46 015, Université d'Angers, France (E.V., J.F., A.-L.G., D.H.).
Arnal JF; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
Lenfant F; From the INSERM-UPS UMR U1048, Institut des Maladies Métaboliques et Cardiovasculaires (M.A., C.F., R.Z., M.B., R.S., T.A., F.B., P.G., H.L., C.F., J.-F.A., F.L.), Université de Toulouse, France.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Sep; Vol. 40 (9), pp. 2143-2158. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Estrogen Replacement Therapy*
Point Mutation*
Carotid Artery Injuries/*drug therapy
Endothelium, Vascular/*drug effects
Estradiol/*pharmacology
Estrogen Receptor alpha/*agonists
Estrogens/*pharmacology
Fertility/*drug effects
Mesenteric Arteries/*drug effects
Animals ; Atherosclerosis/metabolism ; Atherosclerosis/pathology ; Atherosclerosis/prevention & control ; Carotid Artery Injuries/metabolism ; Carotid Artery Injuries/pathology ; Carotid Artery Injuries/physiopathology ; Cell Proliferation/drug effects ; Endothelium, Vascular/injuries ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Enzyme Activation ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Estrous Cycle/drug effects ; Female ; Male ; Mesenteric Arteries/metabolism ; Mesenteric Arteries/physiopathology ; Mice, Inbred C57BL ; Nitric Oxide Synthase Type III/metabolism ; Ovariectomy ; Re-Epithelialization/drug effects ; Signal Transduction ; Time Factors ; Uterus/drug effects ; Uterus/metabolism ; Vascular Remodeling/drug effects ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
The ubiquitin ligase RNF181 stabilizes ERα and modulates breast cancer progression.
Autorzy :
Zhu J; Department of general surgery, the Second Hospital, Cheeloo College of Medicine, Shandong University, 250033, Jinan, China. .
Li X; Xinxiang Key Laboratory of Tumor Migration, Invasion and Precision Medicine, School of Laboratory Medicine, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, 453003,, Henan Province, P.R. China.
Su P; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, 250033, Jinan, China.
Xue M; Xinxiang Key Laboratory of Tumor Migration, Invasion and Precision Medicine, School of Laboratory Medicine, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang, 453003,, Henan Province, P.R. China.
Zang Y; Department of general surgery, the Second Hospital, Cheeloo College of Medicine, Shandong University, 250033, Jinan, China.
Ding Y; Department of general surgery, the Second Hospital, Cheeloo College of Medicine, Shandong University, 250033, Jinan, China. .
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Źródło :
Oncogene [Oncogene] 2020 Oct; Vol. 39 (44), pp. 6776-6788. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents, Hormonal/*pharmacology
Breast Neoplasms/*drug therapy
Estrogen Receptor alpha/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Animals ; Antineoplastic Agents, Hormonal/therapeutic use ; Breast/pathology ; Breast Neoplasms/genetics ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Datasets as Topic ; Disease Progression ; Drug Resistance, Neoplasm/genetics ; Estrogen Receptor alpha/antagonists & inhibitors ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; MCF-7 Cells ; Mice ; Progression-Free Survival ; Protein Domains ; Protein Stability/drug effects ; Sequence Analysis, RNA ; Signal Transduction/drug effects ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer.
Autorzy :
Abderrahman B; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Maximov PY; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Curpan RF; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Hanspal JS; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Fan P; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Xiong R; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Tonetti DA; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Thatcher GRJ; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.).
Jordan VC; Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (B.A., P.Y.M., J.S.H., P.F., V.C.J.); Coriolan Dragulescu Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.); and Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois (R.X., D.A.T., G.R.J.T.) .
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Źródło :
Molecular pharmacology [Mol Pharmacol] 2020 Oct; Vol. 98 (4), pp. 364-381. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Breast Neoplasms/*genetics
Drug Resistance, Neoplasm/*drug effects
Estetrol/*pharmacology
Estrogen Receptor alpha/*metabolism
Estrogens/*pharmacology
Unfolded Protein Response/*drug effects
Breast Neoplasms/drug therapy ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Estrogen Receptor alpha/chemistry ; Estrogens/chemical synthesis ; Estrogens/chemistry ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Regulatory Networks/drug effects ; Humans ; MCF-7 Cells ; Molecular Mimicry ; Molecular Structure
Czasopismo naukowe
Tytuł :
Structures of Endocrine-Disrupting Chemicals Determine Binding to and Activation of the Estrogen Receptor α and Androgen Receptor.
Autorzy :
Tan H; State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, China.
Wang X; State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control, School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China.
Hong H; National Center for Toxicological Research US Food and Drug Administration, 3900 NCTR Rd., Jefferson 72079, Arkansas, United States.
Benfenati E; Laboratory of Environmental Chemistry and Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via G. La Masa 19, Milan 20156, Italy.
Giesy JP; Toxicology Centre, University of Saskatchewan, Saskatoon S7N 5B3, Canada.; Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon S7N 5B4, Canada.; Department of Environmental Sciences, Baylor University, Waco 76706, Texas, United States.
Gini GC; Department of Electronics and Information, Politecnico di Milano, Piazza L. da Vinci 32, Milano 20133, Italy.
Kusko R; Immuneering Corporation, Cambridge 02142, Massachusetts, United States.
Zhang X; State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, China.
Yu H; State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, China.
Shi W; State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, Jiangsu, China.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2020 Sep 15; Vol. 54 (18), pp. 11424-11433. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endocrine Disruptors*
Estrogen Receptor alpha*
Molecular Docking Simulation ; Receptors, Androgen
Czasopismo naukowe
Tytuł :
Calcium and Phosphorus Levels in Saliva are Influenced by Genetic Polymorphisms in Estrogen Receptor Alpha and Microrna17.
Autorzy :
Küchler EC; Department of Pediatric Dentistry, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Gerlach RF; Department of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Cunha AS; Department of Pediatric Dentistry, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Ramazzotto LA; Department of Pediatric Dentistry, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Spada PP; School of Health Sciences, UP - Universidade Positivo, Curitiba, Brazil.
Nelson-Filho P; Department of Pediatric Dentistry, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Ramos J; Department of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dental School, USP - Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Pecharki GD; Department of Community Health, UFPR - Universidade Federal do Paraná, Curitiba, Brazil.
Barbosa F Jr; Department of Clinical, Toxicological and Bromatological Analysis, Faculty of Pharmaceutical Sciences of Ribeirao Preto, USP - Universidade de São Paulo, Ribeirão Preto, Brazil.
Vieira AR; Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA,USA.; Center for Health and Biological Sciences, PUCPR - Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Trevilatto PC; Center for Health and Biological Sciences, PUCPR - Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Brancher JA; School of Health Sciences, UP - Universidade Positivo, Curitiba, Brazil.
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Źródło :
Brazilian dental journal [Braz Dent J] 2020 Sep-Oct; Vol. 31 (5), pp. 466-470.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium*
Estrogen Receptor alpha*/genetics
MicroRNAs*/genetics
Child ; Genetic Predisposition to Disease ; Humans ; Phosphorus ; Polymorphism, Genetic ; Polymorphism, Single Nucleotide ; Saliva
Czasopismo naukowe
Tytuł :
Estrogen Receptor α Regulates Ethanol Excitation of Ventral Tegmental Area Neurons and Binge Drinking in Female Mice.
Autorzy :
Vandegrift BJ; Center for Alcohol Research in Epigenetics and Department of Psychiatry.; Department of Physiology and Biophysics.
Hilderbrand ER; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
Satta R; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
Tai R; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
He D; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
You C; Department of Physiology and Biophysics.
Chen H; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
Xu P; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago, Chicago, Illinois 60612.
Coles C; Center for Alcohol Research in Epigenetics and Department of Psychiatry.
Brodie MS; Center for Alcohol Research in Epigenetics and Department of Psychiatry.; Department of Physiology and Biophysics.
Lasek AW; Center for Alcohol Research in Epigenetics and Department of Psychiatry .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Jul 01; Vol. 40 (27), pp. 5196-5207. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Binge Drinking/*metabolism
Central Nervous System Depressants/*pharmacology
Estrogen Receptor alpha/*metabolism
Ethanol/*pharmacology
Neurons/*drug effects
Ventral Tegmental Area/*drug effects
Animals ; Binge Drinking/psychology ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Estrogen Antagonists/pharmacology ; Estrogen Receptor alpha/agonists ; Estrogen Receptor alpha/genetics ; Estrogen Receptor beta/agonists ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Female ; Gene Knockdown Techniques ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Ovariectomy ; Receptors, AMPA/metabolism ; Ventral Tegmental Area/cytology
Czasopismo naukowe
Tytuł :
Estrogen receptor-positive (ER ) breast cancer treatment: Are multi-target compounds the next promising approach?
Autorzy :
Ferreira Almeida C; UCIBIO.REQUIMTE, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal.
Oliveira A; UCIBIO.REQUIMTE, Computational Biochemistry Laboratory, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal.
João Ramos M; UCIBIO.REQUIMTE, Computational Biochemistry Laboratory, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal.
Fernandes PA; UCIBIO.REQUIMTE, Computational Biochemistry Laboratory, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal.
Teixeira N; UCIBIO.REQUIMTE, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal.
Amaral C; UCIBIO.REQUIMTE, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, n° 228, 4050-313 Porto, Portugal. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Jul; Vol. 177, pp. 113989. Date of Electronic Publication: 2020 Apr 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antineoplastic Agents, Hormonal/*therapeutic use
Aromatase/*genetics
Aromatase Inhibitors/*therapeutic use
Breast Neoplasms/*drug therapy
Estrogen Receptor alpha/*genetics
Androstadienes/therapeutic use ; Aromatase/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Estrogen Receptor alpha/antagonists & inhibitors ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor beta/antagonists & inhibitors ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Fadrozole/therapeutic use ; Female ; Fulvestrant/therapeutic use ; Gene Expression ; Humans ; Molecular Targeted Therapy ; Tamoxifen/therapeutic use
Czasopismo naukowe
Tytuł :
Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice.
Autorzy :
Hewitt SC; Reproductive and Developmental Biology Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA .
Grimm SA; Integrative Bioinformatics Support Group, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA.
Wu SP; Reproductive and Developmental Biology Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA.
DeMayo FJ; Reproductive and Developmental Biology Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA.
Korach KS; Reproductive and Developmental Biology Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina, USA.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jun 19; Vol. 295 (25), pp. 8387-8400. Date of Electronic Publication: 2020 Apr 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Chromatin/*metabolism
Estrogen Receptor alpha/*metabolism
Uterus/*metabolism
Animals ; Binding Sites ; Chromatin/chemistry ; Estradiol/pharmacology ; Estrogen Receptor alpha/deficiency ; Estrogen Receptor alpha/genetics ; Female ; Histones/metabolism ; Homeodomain Proteins/metabolism ; Leukemia Inhibitory Factor/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Protein Binding ; Retinoic Acid Receptor alpha/metabolism ; Signal Transduction ; Transforming Growth Factor beta/metabolism ; Uterus/drug effects
Czasopismo naukowe
Tytuł :
ESR1 Mutations Associated With Estrogen Insensitivity Syndrome Change Conformation of Ligand-Receptor Complex and Altered Transcriptome Profile.
Autorzy :
Li Y; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Hamilton KJ; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Perera L; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Wang T; Integrative Bioinformatics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Gruzdev A; Molecular Genomics Core Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Jefferson TB; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Zhang AX; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Mathura E; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Gerrish KE; Knockout Mouse Core Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Wharey L; Knockout Mouse Core Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Martin NP; Viral Vector Core Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Li JL; Integrative Bioinformatics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
Korach KS; Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, United States.
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Źródło :
Endocrinology [Endocrinology] 2020 Jun 01; Vol. 161 (6).
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Estrogen Receptor alpha/*chemistry
Estrogen Receptor alpha/*genetics
Estrogens/*metabolism
Animals ; Estrogen Receptor alpha/metabolism ; Female ; Humans ; Ligands ; Male ; Mice ; Mice, Inbred C57BL ; Molecular Dynamics Simulation ; Mutation, Missense ; Protein Conformation ; Transcriptome
Czasopismo naukowe
Tytuł :
Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth.
Autorzy :
Böckers M; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany.
Paul NW; Institute for History, Theory and Ethics of Medicine, Johannes Gutenberg University Medical Center, Mainz, Germany.
Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2020 May 15; Vol. 395, pp. 114977. Date of Electronic Publication: 2020 Mar 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*pathology
Estrogen Receptor alpha/*drug effects
Plasticizers/*toxicity
Tritolyl Phosphates/*toxicity
Breast Neoplasms/genetics ; Cell Cycle/genetics ; Endocrine Disruptors ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; HEK293 Cells ; High-Throughput Nucleotide Sequencing ; Humans ; MCF-7 Cells ; Male ; Models, Molecular ; Molecular Docking Simulation ; Neoplasm Invasiveness/genetics ; Neoplasm Metastasis/genetics ; Neovascularization, Pathologic/genetics ; RNA/chemistry ; Transfection ; Tritolyl Phosphates/metabolism
Czasopismo naukowe
Tytuł :
[Effects of UHRF1 on Estrogen Receptor and Proliferation, Invasion and Migration of BCPAP Cells in Thyroid Papillary Carcinoma].
Autorzy :
Xu LW; Department of Biochemistry and Molecular Biology, Institute of Molecular Medicine and Cancer, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Zhang LY; Department of Biochemistry and Molecular Biology, Institute of Molecular Medicine and Cancer, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Gou X; Department of Biochemistry and Molecular Biology, Institute of Molecular Medicine and Cancer, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Qiu YB; Department of Biochemistry and Molecular Biology, Institute of Molecular Medicine and Cancer, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Liu ZM; Department of Biochemistry and Molecular Biology, Institute of Molecular Medicine and Cancer, College of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
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Źródło :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2020 May; Vol. 51 (3), pp. 325-330.
Typ publikacji :
Journal Article
MeSH Terms :
CCAAT-Enhancer-Binding Proteins*/genetics
Carcinoma, Papillary*/genetics
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Thyroid Cancer, Papillary*/genetics
Thyroid Neoplasms*/genetics
Ubiquitin-Protein Ligases*
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Estrogens ; Humans
Czasopismo naukowe

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