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Tytuł :
Thermosensitive TRPV4 channels mediate temperature-dependent microglia movement.
Autorzy :
Nishimoto R; Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Department of Anesthesiology and Resuscitology, Okayama University Hospital, 700-8558 Okayama, Japan.
Derouiche S; Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Thermal Biology Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.
Eto K; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Division of Homeostatic Development, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8585 Okazaki, Japan.
Deveci A; Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Thermal Biology Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.
Kashio M; Department of Physiology, Aichi Medical University, 480-1195 Nagakute, Japan.
Kimori Y; Department of Management and Information Sciences, Faculty of Environmental and Information Sciences, Fukui University of Technology, 910-8505 Fukui, Japan.
Matsuoka Y; Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 700-8558 Okayama, Japan.
Morimatsu H; Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 700-8558 Okayama, Japan.
Nabekura J; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Division of Homeostatic Development, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8585 Okazaki, Japan.
Tominaga M; Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan; .; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), 444-8585 Okazaki, Japan.; Thermal Biology Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 444-8787 Okazaki, Japan.; Institute for Environmental and Gender-Specific Medicine, Juntendo University, 279-0021 Chiba, Japan.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Apr 27; Vol. 118 (17).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Photoactivatable CaMKII induces synaptic plasticity in single synapses.
Autorzy :
Shibata ACE; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Ueda HH; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.; Department of Physiological Sciences, The Graduate University for Advanced Studies, Hayama, Kanagawa, 240-0193, Japan.
Eto K; Department of Physiological Sciences, The Graduate University for Advanced Studies, Hayama, Kanagawa, 240-0193, Japan.; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Onda M; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Sato A; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Ohba T; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Nabekura J; Department of Physiological Sciences, The Graduate University for Advanced Studies, Hayama, Kanagawa, 240-0193, Japan.; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Murakoshi H; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan. .; Department of Physiological Sciences, The Graduate University for Advanced Studies, Hayama, Kanagawa, 240-0193, Japan. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 02; Vol. 12 (1), pp. 751. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism
Long-Term Potentiation/*physiology
Optogenetics/*methods
Synapses/*metabolism
Animals ; Electrophysiology ; Female ; HeLa Cells ; Hippocampus/metabolism ; Hippocampus/physiology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Neuronal Plasticity/physiology ; Receptors, AMPA/genetics ; Receptors, AMPA/metabolism ; Signal Transduction/genetics ; Signal Transduction/physiology ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Histamine depolarizes rat intracardiac ganglion neurons through the activation of TRPC non-selective cation channels.
Autorzy :
Sato A; Department of Pediatrics, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Arichi S; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Kojima F; Department of Pharmacology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Hayashi T; Department of Anatomical Science, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Ohba T; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Cheung DL; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Eto K; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Narushima M; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Murakoshi H; Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Maruo Y; Department of Pediatrics, Shiga University of Medical Science, Otsu, Shiga, 520-2192, Japan.
Kadoya Y; Department of Anatomical Science, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi, 444-8585, Japan.
Ishibashi H; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa, 252-0373, Japan. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2020 Nov 05; Vol. 886, pp. 173536. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji :
Journal Article
MeSH Terms :
Ganglia/*cytology
Ganglia/*drug effects
Heart/*drug effects
Heart/*innervation
Histamine/*pharmacology
Ion Channels/*drug effects
Neurons/*drug effects
TRPC Cation Channels/*drug effects
Animals ; Calcium Signaling/drug effects ; Female ; Histamine Agonists/pharmacology ; Histamine H1 Antagonists/pharmacology ; Male ; Meglumine/pharmacology ; Patch-Clamp Techniques ; Potassium Channels/drug effects ; Pyridines/pharmacology ; Rats ; Rats, Wistar ; Triprolidine/pharmacology ; Type C Phospholipases/drug effects
Czasopismo naukowe
Tytuł :
Overexpression of neuronal K co-transporter enhances dendritic spine plasticity and motor learning.
Autorzy :
Nakamura K; Division of Homeostatic Development, Department of Fundamental Neuroscience, National Institutes for Physiological Sciences, Okazaki, 444-8585, Japan.; Department of Physiological Sciences, Sokendai, Hayama, 240-0193, Japan.
Moorhouse AJ; Department of Physiology, School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia.
Cheung DL; Department of Physiology, School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia.
Eto K; Division of Homeostatic Development, Department of Fundamental Neuroscience, National Institutes for Physiological Sciences, Okazaki, 444-8585, Japan.
Takeda I; Division of Homeostatic Development, Department of Fundamental Neuroscience, National Institutes for Physiological Sciences, Okazaki, 444-8585, Japan.
Rozenbroek PW; Department of Physiology, School of Medical Sciences, University of New South Wales, Sydney, 2052, Australia.
Nabekura J; Division of Homeostatic Development, Department of Fundamental Neuroscience, National Institutes for Physiological Sciences, Okazaki, 444-8585, Japan. .; Department of Physiological Sciences, Sokendai, Hayama, 240-0193, Japan. .
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Źródło :
The journal of physiological sciences : JPS [J Physiol Sci] 2019 May; Vol. 69 (3), pp. 453-463. Date of Electronic Publication: 2019 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Dendritic Spines/*metabolism
Dendritic Spines/*physiology
Learning/*physiology
Motor Cortex/*metabolism
Motor Cortex/*physiology
Neuronal Plasticity/*physiology
Symporters/*metabolism
Animals ; Dendrites/metabolism ; Dendrites/physiology ; Male ; Mice ; Mice, Transgenic ; Pyramidal Cells/metabolism ; Pyramidal Cells/physiology ; Synapses/metabolism ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Microglia mediate non-cell-autonomous cell death of retinal ganglion cells.
Autorzy :
Takeda A; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Shinozaki Y; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kashiwagi K; Department of Ophthalmology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Ohno N; Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences (NIPS), Aichi, Japan.; Department of Anatomy, Jichi Medical University, Tochigi, Japan.
Eto K; Division of Homeostatic Development, NIPS, Aichi, Japan.
Wake H; Division of Homeostatic Development, NIPS, Aichi, Japan.; Division of System Neuroscience, Graduate School of Medicine, Kobe University, Hyogo, Japan.; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama, Japan.
Nabekura J; Division of Homeostatic Development, NIPS, Aichi, Japan.
Koizumi S; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
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Źródło :
Glia [Glia] 2018 Nov; Vol. 66 (11), pp. 2366-2384. Date of Electronic Publication: 2018 Oct 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Death/*physiology
Cytokines/*metabolism
Microglia/*physiology
Retinal Ganglion Cells/*physiology
Aminopyridines/pharmacology ; Animals ; Animals, Newborn ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Cell Death/drug effects ; Cells, Cultured ; Cytokines/genetics ; Excitatory Amino Acid Agonists/pharmacology ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Microglia/drug effects ; Microglia/ultrastructure ; N-Methylaspartate/pharmacology ; Nerve Degeneration/chemically induced ; Optic Nerve Injuries/chemically induced ; Organic Chemicals/pharmacology ; Pyrroles/pharmacology ; Retinal Ganglion Cells/drug effects ; Retinal Ganglion Cells/ultrastructure ; Signal Transduction/drug effects ; Transcription Factor Brn-3A/genetics ; Transcription Factor Brn-3A/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Cortical astrocytes prime the induction of spine plasticity and mirror image pain.
Autorzy :
Ishikawa T; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Brain Structures and Functions, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Okazaki, Japan.
Kim SK; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Okazaki, Japan.; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Wake H; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Okazaki, Japan.; Division of System Neuroscience, Kobe University Graduate School of Medicine, Kobe, Japan.
Takeda I; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.
Horiuchi H; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.
Moorhouse AJ; Department of Physiology, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales, Australia.
Ishibashi H; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Okazaki, Japan.; Department of Physiology, Kitasato University School of Allied Health Sciences, Sagamihara, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Okazaki, Japan.; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan.
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Źródło :
Pain [Pain] 2018 Aug; Vol. 159 (8), pp. 1592-1606.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*physiology
Cerebral Cortex/*physiopathology
Dendritic Spines/*physiology
Neuronal Plasticity/*physiology
Neurons/*physiology
Peripheral Nerve Injuries/*physiopathology
Animals ; Astrocytes/cytology ; Cerebral Cortex/cytology ; Male ; Mice ; Neurons/cytology ; Sciatic Nerve/injuries
Czasopismo naukowe
Tytuł :
Activity-dependent functions of non-electrical glial cells.
Autorzy :
Kato D; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Neurology, Nagoya City University of Graduate School of Medical Sciences, Nagoya, Japan.
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama, Japan.
Wake H; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan.; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama, Japan.; Division System Neuroscience, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho Chuo-ku, Kobe 650-0017, Japan.; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama, Japan.
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Źródło :
Journal of biochemistry [J Biochem] 2018 Jun 01; Vol. 163 (6), pp. 457-464.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuroglia/*physiology
Animals ; Brain/cytology ; Brain/physiology ; Humans
Czasopismo naukowe
Tytuł :
The roles of cortical astrocytes in chronic pain and other brain pathologies.
Autorzy :
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan; Department of Physiological Sciences, The Graduate School for Advanced Studies, Hayama, Kanagawa 240-0193, Japan.
Kim SK; Department of Physiology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Takeda I; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan; Department of Physiological Sciences, The Graduate School for Advanced Studies, Hayama, Kanagawa 240-0193, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Tokyo 102-0076, Japan. Electronic address: .
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Źródło :
Neuroscience research [Neurosci Res] 2018 Jan; Vol. 126, pp. 3-8. Date of Electronic Publication: 2017 Sep 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Astrocytes/*physiology
Brain/*physiopathology
Chronic Pain/*physiopathology
Animals ; Cerebral Cortex/physiopathology ; Humans ; Neuronal Plasticity ; Neurons/physiology ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Astrocytes with previous chronic exposure to amyloid β-peptide fragment 1-40 suppress excitatory synaptic transmission.
Autorzy :
Kawano H; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Oyabu K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Yamamoto H; Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Aoba-ku, Sendai, Japan.
Eto K; Division of Homeostatic Development, Department of Fundamental Neuroscience, National Institute for Physiological Sciences, Okazaki, Japan.; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan.
Adaniya Y; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Kubota K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, Fukuoka, Japan.
Watanabe T; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, Fukuoka, Japan.
Hirano-Iwata A; Advanced Institute for Materials Research, Tohoku University, Aoba-ku, Sendai, Japan.; Research Institute of Electrical Communication, Tohoku University, Aoba-ku, Sendai, Japan.
Nabekura J; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan.; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Japan.; CREST, Japan Science and Technology Agency (JST), Kawaguchi, Japan.
Katsurabayashi S; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.
Iwasaki K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan.; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, Fukuoka, Japan.
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Źródło :
Journal of neurochemistry [J Neurochem] 2017 Dec; Vol. 143 (6), pp. 624-634. Date of Electronic Publication: 2017 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease*
Amyloid beta-Peptides/*toxicity
Astrocytes/*metabolism
Peptide Fragments/*toxicity
Synaptic Transmission/*physiology
Animals ; Astrocytes/drug effects ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Mice ; Synaptic Transmission/drug effects
Czasopismo naukowe
Tytuł :
Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons.
Autorzy :
Nakahata Y; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8585, Japan.
Eto K; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8585, Japan.
Murakoshi H; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8585, Japan; Supportive Center for Brain Research, National Institute for Physiological Science, Okazaki 444-8585, Japan; PRESTO, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan.
Watanabe M; Department of Neurophysiology, Hamamatsu University School of Medicine , Hamamatsu 431-3192, Japan.
Kuriu T; Department of Neurophysiology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University , Tokushima 769-2193, Japan.
Hirata H; PRESTO, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan; Division of Molecular and Developmental Biology, National Institute of Genetics, Mishima 411-8540, Japan; Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Mishima 411-8540, Japan; Department of Chemistry and Biological Science, Graduate School of Science and Engineering, Aoyama Gakuin University, Sagamihara 252-5258, Japan.
Moorhouse AJ; Department of Physiology, School of Medical Sciences, University of New South Wales , Sydney 2052, Australia.
Ishibashi H; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8585, Japan; Department of Physiology, Kitasato University School of Allied Health Sciences, Sagamihara 252-0373, Japan.
Nabekura J; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8585, Japan; CREST, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan.
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Źródło :
ENeuro [eNeuro] 2017 Feb 06; Vol. 4 (1). Date of Electronic Publication: 2017 Feb 06 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Inhibitory Postsynaptic Potentials/*physiology
Neurons/*metabolism
Protein Transport/*physiology
Receptors, Glycine/*metabolism
Spinal Cord/*cytology
Action Potentials/drug effects ; Action Potentials/genetics ; Animals ; Animals, Newborn ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cells, Cultured ; Embryo, Mammalian ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; Glycine Agents/pharmacology ; Inhibitory Postsynaptic Potentials/drug effects ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/drug effects ; Photobleaching ; Protein Transport/drug effects ; Receptors, Glycine/genetics ; Strychnine/pharmacology ; Vesicular Inhibitory Amino Acid Transport Proteins/genetics ; Vesicular Inhibitory Amino Acid Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Microglia contact induces synapse formation in developing somatosensory cortex.
Autorzy :
Miyamoto A; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.
Wake H; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama 240-0193, Japan.; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama 102-0076, Japan.
Ishikawa AW; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama 240-0193, Japan.; Division of Visual Information Processing, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama 240-0193, Japan.
Shibata K; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.; Department of Pharmacology, Graduated School of Medical and Engineering, Yamanashi University, Chuo 409-3898, Japan.
Murakoshi H; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Saitama 102-0076, Japan.; Section of Multiphoton Neuroimaging, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.
Koizumi S; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.; Department of Pharmacology, Graduated School of Medical and Engineering, Yamanashi University, Chuo 409-3898, Japan.
Moorhouse AJ; School of Medical Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia.
Yoshimura Y; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama 240-0193, Japan.; Division of Visual Information Processing, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan.; Department of Physiological Sciences, The Graduate School for Advanced Study, Hayama 240-0193, Japan.
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Źródło :
Nature communications [Nat Commun] 2016 Aug 25; Vol. 7, pp. 12540. Date of Electronic Publication: 2016 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microglia/*physiology
Neurogenesis/*physiology
Pyramidal Cells/*physiology
Somatosensory Cortex/*embryology
Synapses/*physiology
Animals ; Dendrites/physiology ; Dendrites/ultrastructure ; Female ; Immune System/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microglia/ultrastructure ; Microscopy, Fluorescence, Multiphoton ; Models, Animal ; Pseudopodia/physiology ; Pseudopodia/ultrastructure ; Pyramidal Cells/cytology ; Pyramidal Cells/ultrastructure ; Somatosensory Cortex/ultrastructure ; Spine/embryology ; Spine/ultrastructure ; Synapses/ultrastructure
Czasopismo naukowe
Tytuł :
Microglial Contact Prevents Excess Depolarization and Rescues Neurons from Excitotoxicity.
Autorzy :
Kato G; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan.
Inada H; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan.
Wake H; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan; Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Kawaguchi 332-0012, Saitama, Japan.
Akiyoshi R; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan.
Miyamoto A; Divison of Homeostatic Development, National Institute for Physiological Sciences , Okazaki 444-8585, Japan.
Eto K; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan.
Ishikawa T; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan.
Moorhouse AJ; Department of Physiology, School of Medical Sciences, University of New South Wales , Sydney 2052, New South Wales, Australia.
Strassman AM; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, Massachusetts 02215.
Nabekura J; Divison of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan; Department of Physiological Sciences, The Graduate University for Advanced Studies, Okazaki 444-8585, Nishigo-naka, Myodaiji-cho, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Agency for Medical Research and Development (AMED), Tokyo, Japan.
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Źródło :
ENeuro [eNeuro] 2016 Jun 21; Vol. 3 (3). Date of Electronic Publication: 2016 Jun 21 (Print Publication: 2016).
Typ publikacji :
Journal Article; Video-Audio Media; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Potentials/*physiology
Microglia/*physiology
Neuroprotection/*physiology
Pyramidal Cells/*physiology
Adenosine Triphosphate/metabolism ; Animals ; Axons/drug effects ; Axons/pathology ; Axons/physiology ; Cell Movement/drug effects ; Cell Movement/physiology ; Cell Size ; Dendrites/drug effects ; Dendrites/pathology ; Dendrites/physiology ; Female ; Glutamic Acid/metabolism ; Ion Channels/metabolism ; Male ; Membrane Potentials/drug effects ; Mice, Transgenic ; Microglia/drug effects ; Microglia/pathology ; Neuroprotection/drug effects ; Pyramidal Cells/drug effects ; Pyramidal Cells/pathology ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Noradrenergic refinement of glutamatergic neuronal circuits in the lateral superior olivary nucleus before hearing onset.
Autorzy :
Hirao K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan; Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan;
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan;
Nakahata Y; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan;
Ishibashi H; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan; and.
Nagai T; Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Nabekura J; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki, Japan; Department of Physiological Sciences, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), Okazaki, Japan; .
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Źródło :
Journal of neurophysiology [J Neurophysiol] 2015 Sep; Vol. 114 (3), pp. 1974-86. Date of Electronic Publication: 2015 Jul 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hearing*
Neurogenesis*
Glutamic Acid/*metabolism
Neurons/*physiology
Norepinephrine/*metabolism
Olivary Nucleus/*physiology
Adrenergic alpha-2 Receptor Agonists/pharmacology ; Animals ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Mice ; Mice, Inbred BALB C ; Neurons/drug effects ; Neurons/metabolism ; Olivary Nucleus/cytology ; Olivary Nucleus/growth & development ; Receptors, Adrenergic, alpha-2/metabolism
Czasopismo naukowe
Tytuł :
In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS.
Autorzy :
Takihara Y; Department of Ophthalmology, Faculty of Medical Science, University of Fukui, Fukui 910-1193, Japan; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan;
Inatani M; Department of Ophthalmology, Faculty of Medical Science, University of Fukui, Fukui 910-1193, Japan; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan; .
Eto K; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Aichi 444-8585, Japan; Department of Physiological Sciences, SOKENDAI (The Graduate University for Advanced Studies), Aichi 444-8585, Japan;
Inoue T; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan;
Kreymerman A; Shiley Eye Institute, University of California, San Diego, La Jolla, CA 92093;
Miyake S; Department of Ophthalmology, Faculty of Medical Science, University of Fukui, Fukui 910-1193, Japan;
Ueno S; Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan;
Nagaya M; Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan;
Nakanishi A; Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan;
Iwao K; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan;
Takamura Y; Department of Ophthalmology, Faculty of Medical Science, University of Fukui, Fukui 910-1193, Japan;
Sakamoto H; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Okayama 701-4303, Japan;
Satoh K; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Okayama 701-4303, Japan;
Kondo M; Department of Ophthalmology, Mie University Graduate School of Medicine, Mie 514-8507, Japan.
Sakamoto T; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Okayama 701-4303, Japan;
Goldberg JL; Shiley Eye Institute, University of California, San Diego, La Jolla, CA 92093;
Nabekura J; Division of Homeostatic Development, Department of Developmental Physiology, National Institute for Physiological Sciences, Aichi 444-8585, Japan; Department of Physiological Sciences, SOKENDAI (The Graduate University for Advanced Studies), Aichi 444-8585, Japan;
Tanihara H; Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan;
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Aug 18; Vol. 112 (33), pp. 10515-20. Date of Electronic Publication: 2015 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging*
Axonal Transport/*physiology
Central Nervous System/*pathology
Central Nervous System/*physiology
Mitochondria/*physiology
Retinal Ganglion Cells/*physiology
Animals ; Axons/physiology ; Biological Transport ; Disease Models, Animal ; Female ; Glaucoma/pathology ; Glaucoma/physiopathology ; Imaging, Three-Dimensional ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Optic Nerve/pathology ; Photons ; Retina/cytology ; Sclera/physiopathology ; Time Factors
Czasopismo naukowe
Tytuł :
A double bond-conjugated dimethylnitrobenzene-type photolabile nitric oxide donor with improved two-photon cross section.
Autorzy :
Ieda N; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan.
Hishikawa K; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan.
Eto K; National Institute of Physiological Sciences, 444-8585, Japan.
Kitamura K; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan.
Kawaguchi M; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan.
Suzuki T; Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 606-0823, Japan.
Fukuhara K; Showa University School of Pharmacy, 142-8555, Japan.
Miyata N; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan.
Furuta T; Department of Biomolecular Science, Toho University, 274-8510, Japan.
Nabekura J; National Institute of Physiological Sciences, 444-8585, Japan.
Nakagawa H; Graduate School of Pharmaceutical Sciences, Nagoya City University, 467-8603, Japan. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Aug 15; Vol. 25 (16), pp. 3172-5. Date of Electronic Publication: 2015 Jun 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nitric Oxide Donors/*chemistry
Nitrobenzenes/*chemistry
Electron Spin Resonance Spectroscopy ; Fluoresceins/chemistry ; Fluoresceins/metabolism ; HCT116 Cells ; Humans ; Microscopy, Fluorescence ; Nitric Oxide/metabolism ; Nitric Oxide Donors/metabolism ; Nitrobenzenes/metabolism
Czasopismo naukowe
Tytuł :
Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.
Autorzy :
Zhao H; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Aoshi T; Laboratory of Vaccine Science, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation (NIBIO), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
Kawai S; Departments of Tropical Medicine and Parasitology, Dokkyo University School of Medicine, Mibu, Tochigi 321-0293, Japan.
Mori Y; Laboratory of Biofunctional Imaging, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Konishi A; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Ozkan M; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Fujita Y; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Haseda Y; Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation (NIBIO), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
Shimizu M; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kohyama M; Laboratory of Immunochemistry, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kobiyama K; Laboratory of Vaccine Science, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation (NIBIO), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
Eto K; Division of Homeostatic Development Unit, National Institute for Physiological Sciences, 38 Nishigonaka Myodaiji, Okazaki, Aichi 444-8585, Japan.
Nabekura J; Division of Homeostatic Development Unit, National Institute for Physiological Sciences, 38 Nishigonaka Myodaiji, Okazaki, Aichi 444-8585, Japan.
Horii T; Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Ishino T; Department of Medical Zoology, Mie University School of Medicine, Mie, Tsu 514-0001, Japan.
Yuda M; Department of Medical Zoology, Mie University School of Medicine, Mie, Tsu 514-0001, Japan.
Hemmi H; Laboratory of Immune Regulation, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kaisho T; Laboratory of Immune Regulation, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Akira S; Laboratory of Host Defense, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kinoshita M; Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.
Tohyama K; Laboratory for Nano-neuroanatomy, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan.
Yoshioka Y; Laboratory of Biofunctional Imaging, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Ishii KJ; Laboratory of Vaccine Science, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation (NIBIO), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
Coban C; Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2014 May 14; Vol. 15 (5), pp. 551-63.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Malaria, Cerebral/*parasitology
Olfactory Bulb/*parasitology
Plasmodium falciparum/*physiology
Animals ; CD8-Positive T-Lymphocytes/immunology ; Chemokine CCL21/genetics ; Chemokine CCL21/immunology ; Female ; Humans ; Malaria, Cerebral/genetics ; Malaria, Cerebral/immunology ; Malaria, Cerebral/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Olfactory Bulb/immunology ; Olfactory Bulb/pathology ; Plasmodium falciparum/pathogenicity ; Receptors, CCR7/genetics ; Receptors, CCR7/immunology ; Receptors, CXCR3/genetics ; Receptors, CXCR3/immunology ; Virulence
Czasopismo naukowe
Tytuł :
Fine spatiotemporal control of nitric oxide release by infrared pulse-laser irradiation of a photolabile donor.
Autorzy :
Nakagawa H; Graduate School of Pharmaceutical Sciences, Nagoya City University , 3-1, Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.
Hishikawa K
Eto K
Ieda N
Namikawa T
Kamada K
Suzuki T
Miyata N
Nabekura J
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Źródło :
ACS chemical biology [ACS Chem Biol] 2013 Nov 15; Vol. 8 (11), pp. 2493-500. Date of Electronic Publication: 2013 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Infrared Rays*
Fluoresceins/*chemistry
Nitric Oxide/*chemistry
Nitrobenzenes/*chemistry
Animals ; Brain/drug effects ; Cell Line, Tumor ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Confocal ; Nitric Oxide/metabolism
Czasopismo naukowe
Tytuł :
[Mechanisms of neural circuit remodeling in the primary somatosensory cortex in mouse models of chronic pain].
Autorzy :
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Japan.
Ishikawa T
Sun Kwang K
Nabekura J
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Źródło :
Brain and nerve = Shinkei kenkyu no shinpo [Brain Nerve] 2013 Jun; Vol. 65 (6), pp. 623-33.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Brain Mapping*
Chronic Pain/*physiopathology
Somatosensory Cortex/*physiopathology
Animals ; Disease Models, Animal ; Humans ; Neurons/physiology ; Spinal Cord/physiology
Czasopismo naukowe
Tytuł :
Critical role of the astrocyte for functional remodeling in contralateral hemisphere of somatosensory cortex after stroke.
Autorzy :
Takatsuru Y; Department of Integrative Physiology, and Institute of Experimental Animal Research, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan. />Eto K
Kaneko R
Masuda H
Shimokawa N
Koibuchi N
Nabekura J
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2013 Mar 13; Vol. 33 (11), pp. 4683-92.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*physiology
Functional Laterality/*physiology
Somatosensory Cortex/*physiopathology
Stroke/*pathology
Aminomethyltransferase/genetics ; Aminomethyltransferase/metabolism ; Analysis of Variance ; Animals ; Aspartic Acid/analogs & derivatives ; Aspartic Acid/therapeutic use ; Calcium/metabolism ; Disease Models, Animal ; Excitatory Amino Acid Transporter 1/genetics ; Excitatory Amino Acid Transporter 1/metabolism ; Excitatory Amino Acid Transporter 2/genetics ; Excitatory Amino Acid Transporter 2/metabolism ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/physiology ; Glutamic Acid/metabolism ; Glycine/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Microdialysis ; Motor Activity ; Neurons/metabolism ; Physical Stimulation ; RNA, Messenger/metabolism ; Somatosensory Cortex/drug effects ; Somatosensory Cortex/pathology ; Stroke/drug therapy ; Time Factors ; Vibrissae/innervation
Czasopismo naukowe
Tytuł :
Enhanced GABAergic activity in the mouse primary somatosensory cortex is insufficient to alleviate chronic pain behavior with reduced expression of neuronal potassium-chloride cotransporter.
Autorzy :
Eto K; Division of Homeostatic Development, National Institute for Physiological Sciences, Okazaki 444-8585, Japan.
Ishibashi H
Yoshimura T
Watanabe M
Miyamoto A
Ikenaka K
Moorhouse AJ
Nabekura J
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2012 Nov 21; Vol. 32 (47), pp. 16552-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chronic Pain/*psychology
Somatosensory Cortex/*physiology
Symporters/*physiology
gamma-Aminobutyric Acid/*physiology
Animals ; Blotting, Western ; Calcium/metabolism ; Electric Stimulation ; GABA Antagonists/pharmacology ; Hyperalgesia/physiopathology ; Image Processing, Computer-Assisted ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Fluorescence ; Pain Measurement ; Pain Threshold/physiology ; Patch-Clamp Techniques ; Receptors, GABA-A/drug effects ; Symporters/biosynthesis
Czasopismo naukowe

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