Temat: "Excitatory Amino Acid Antagonists" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The psychotomimetic ketamine disrupts the transfer of late sensory information in the corticothalamic network.
Autorzy:: Qin Y; Université de Strasbourg, Strasbourg, France.; INSERM U1114, Neuropsychologie cognitive et physiopathologie de la schizophrénie, Strasbourg, France.; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de médecine, Strasbourg, France.; Centre de Recherche en Biomédecine de Strasbourg (CRBS), Strasbourg, France.; Netherlands Institute for Neuroscience, The Netherlands.
Mahdavi A; Université de Strasbourg, Strasbourg, France.; INSERM U1114, Neuropsychologie cognitive et physiopathologie de la schizophrénie, Strasbourg, France.; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de médecine, Strasbourg, France.; Centre de Recherche en Biomédecine de Strasbourg (CRBS), Strasbourg, France.; The University of Freiburg, Bernstein Center Freiburg, Freiburg, Germany.
Bertschy M; Université de Strasbourg, Strasbourg, France.; INSERM U1114, Neuropsychologie cognitive et physiopathologie de la schizophrénie, Strasbourg, France.; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de médecine, Strasbourg, France.; Centre de Recherche en Biomédecine de Strasbourg (CRBS), Strasbourg, France.
Anderson PM; Dept. Cognitive Neurobiology, Center for Brain Research, Medical University Vienna, Austria.
Kulikova S; National Research University Higher School of Economics, Perm, Russia.
Pinault D; Université de Strasbourg, Strasbourg, France.; INSERM U1114, Neuropsychologie cognitive et physiopathologie de la schizophrénie, Strasbourg, France.; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de médecine, Strasbourg, France.; Centre de Recherche en Biomédecine de Strasbourg (CRBS), Strasbourg, France.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2023 Feb; Vol. 57 (3), pp. 440-455. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ketamine*/pharmacology
Rats ; Animals ; Excitatory Amino Acid Antagonists/pharmacology ; Receptors, N-Methyl-D-Aspartate ; Brain ; Thalamus

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Skocz do pozycji: 2.

Tytuł:: Ketamine: Linking NMDA receptor hypofunction, gamma oscillations and psychosis (commentary on Qin et al., 2022).
Autorzy:: Reilly TJ; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2023 Feb; Vol. 57 (3), pp. 456-457. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:: Ketamine*/pharmacology
Psychotic Disorders*/drug therapy
Humans ; Receptors, N-Methyl-D-Aspartate/physiology ; Excitatory Amino Acid Antagonists

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Skocz do pozycji: 3.

Tytuł:: Arc expression regulates long‐term potentiation magnitude and metaplasticity in area CA1 of the hippocampus in ArcKR mice.
Autorzy:: Haley, Maisy
Bertrand, Jeanri
Anderson, Vanessa Torrico
Fuad, Mukattar
Frenguelli, Bruno G.
Corrêa, Sonia A. L.
Wall, Mark J.; Pokaż więcej
Temat:: LONG-term potentiation
GENE expression
NEURAL transmission
NEUROPLASTICITY
HIPPOCAMPUS (Brain)
EXCITATORY amino acid antagonists
Źródło:: European Journal of Neuroscience; Nov2023, Vol. 58 Issue 10, p4166-4180, 15p

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Skocz do pozycji: 4.

Tytuł:: N-Methyl-d-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats.
Autorzy:: Hoffmann J; Department of Neurology, University of California, San Francisco, California, USA.; Headache Group, Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Storer RJ; Department of Neurology, University of California, San Francisco, California, USA.; Office of Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Park JW; Department of Neurology, Catholic University, Seoul, South Korea.
Goadsby PJ; Department of Neurology, University of California, San Francisco, California, USA.; Headache Group, Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2019 Sep; Vol. 50 (5), pp. 2847-2859. Date of Electronic Publication: 2019 Jun 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Excitatory Amino Acid Antagonists/*pharmacology
Magnesium/*pharmacology
Memantine/*pharmacology
Neurons/*drug effects
Nociception/*drug effects
Synaptic Transmission/*drug effects
Animals ; Glutamic Acid/pharmacology ; Male ; N-Methylaspartate/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Synapses/drug effects ; Trigeminal Nuclei/drug effects

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Skocz do pozycji: 5.

Tytuł:: Role of NMDA and AMPA glutamatergic receptors in the effects of social defeat on the rewarding properties of MDMA in mice.
Autorzy:: García-Pardo MP; Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología, Universidad de Valencia, Avda. Blasco Ibáñez, 21, 46010, Valencia, Spain.; Unitat Predepartamental de Medicina, Facultat de Ciències de la Salut, Universitat Jaume I. Castelló de la Plana, Castelló, Spain.
Miñarro J; Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología, Universidad de Valencia, Avda. Blasco Ibáñez, 21, 46010, Valencia, Spain.
Llansola M; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, Valencia, Spain.
Felipo V; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, Valencia, Spain.
Aguilar MA; Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología, Universidad de Valencia, Avda. Blasco Ibáñez, 21, 46010, Valencia, Spain.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2019 Aug; Vol. 50 (3), pp. 2623-2634. Date of Electronic Publication: 2018 Oct 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Reward*
Social Behavior*
N-Methyl-3,4-methylenedioxyamphetamine/*pharmacology
Receptors, AMPA/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Stress, Psychological/*metabolism
Adrenergic Uptake Inhibitors/pharmacology ; Animals ; Conditioning, Psychological/drug effects ; Conditioning, Psychological/physiology ; Excitatory Amino Acid Antagonists/pharmacology ; Male ; Mice ; Receptors, AMPA/antagonists & inhibitors ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Stress, Psychological/psychology

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Skocz do pozycji: 6.

Tytuł:: mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation.
Autorzy:: Loweth JA; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Reimers JM; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Caccamise A; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Stefanik MT; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Woo KKY; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Chauhan NM; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Werner CT; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Wolf ME; Department of Neuroscience, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2019 Aug; Vol. 50 (3), pp. 2590-2601. Date of Electronic Publication: 2018 Oct 14.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium/*metabolism
Nucleus Accumbens/*metabolism
Protein Biosynthesis/*physiology
Receptors, AMPA/*metabolism
Receptors, Metabotropic Glutamate/*metabolism
Tretinoin/*metabolism
Animals ; Benzoates/pharmacology ; Cells, Cultured ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; Glycine/analogs & derivatives ; Glycine/pharmacology ; Methoxyhydroxyphenylglycol/analogs & derivatives ; Methoxyhydroxyphenylglycol/pharmacology ; Mice ; Mice, 129 Strain ; Mice, Transgenic ; Neurons/drug effects ; Neurons/metabolism ; Nucleus Accumbens/cytology ; Nucleus Accumbens/drug effects ; Pregnancy ; Protein Biosynthesis/drug effects ; Rats ; Rats, Sprague-Dawley ; Receptors, AMPA/antagonists & inhibitors ; Receptors, Metabotropic Glutamate/antagonists & inhibitors ; Signal Transduction/drug effects ; Signal Transduction/physiology

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Skocz do pozycji: 7.

Tytuł:: N-methyl-d-aspartate receptors, learning and memory: chronic intraventricular infusion of the NMDA receptor antagonist d-AP5 interacts directly with the neural mechanisms of spatial learning.
Autorzy:: Morris RG; Laboratory for Cognitive Neuroscience, Centre for Cognitive and Neural Systems, The University of Edinburgh, Edinburgh, UK. />Steele RJ
Bell JE
Martin SJ; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2013 Mar; Vol. 37 (5), pp. 700-17. Date of Electronic Publication: 2013 Jan 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 2-Amino-5-phosphonovalerate/*pharmacology
Excitatory Amino Acid Antagonists/*pharmacology
Maze Learning/*drug effects
Memory/*drug effects
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
2-Amino-5-phosphonovalerate/administration & dosage ; Animals ; Cerebral Cortex/cytology ; Cerebral Cortex/drug effects ; Cerebral Cortex/physiology ; Cues ; Excitatory Amino Acid Antagonists/administration & dosage ; Female ; Hippocampus/cytology ; Hippocampus/drug effects ; Hippocampus/physiology ; Infusions, Intraventricular ; Infusions, Spinal ; Male ; Rats ; Rats, Wistar

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Skocz do pozycji: 8.

Tytuł:: Effects of chronic ketamine on hippocampal cross-frequency coupling: implications for schizophrenia pathophysiology.
Autorzy:: Michaels TI; Psychological Sciences Department, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Long LL; Psychological Sciences Department, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Stevenson IH; Psychological Sciences Department, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Chrobak JJ; Psychological Sciences Department, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.
Chen CA; Psychological Sciences Department, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, 06269, USA.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2018 Oct; Vol. 48 (8), pp. 2903-2914. Date of Electronic Publication: 2018 Feb 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Excitatory Amino Acid Antagonists/*administration & dosage
Gamma Rhythm/*physiology
Hippocampus/*physiopathology
Ketamine/*administration & dosage
Schizophrenia/*physiopathology
Theta Rhythm/*physiology
Animals ; Gamma Rhythm/drug effects ; Hippocampus/drug effects ; Male ; Rats ; Rats, Long-Evans ; Theta Rhythm/drug effects

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Skocz do pozycji: 9.

Tytuł:: Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus accumbens.
Autorzy:: Neigh-McCandless G; Department of Psychology, The Ohio State University, Columbus, OH 43210, USA.
Kravitz BA
Sarter M
Bruno JP; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2002 Oct; Vol. 16 (7), pp. 1259-66.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Acetylcholine/*analysis
Excitatory Amino Acid Antagonists/*pharmacology
Kynurenic Acid/*pharmacology
Prefrontal Cortex/*metabolism
Animals ; Dose-Response Relationship, Drug ; Excitatory Amino Acid Antagonists/administration & dosage ; Kynurenic Acid/administration & dosage ; Male ; Microdialysis ; N-Methylaspartate/antagonists & inhibitors ; Nucleus Accumbens/metabolism ; Prefrontal Cortex/drug effects ; Quinoxalines/pharmacology ; Rats

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Skocz do pozycji: 10.

Tytuł:: The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice.
Autorzy:: Boerner, Thomas
Bygrave, Alexei M.
Chen, Jingkai
Fernando, Anushka
Jackson, Stephanie
Barkus, Chris
Sprengel, Rolf
Seeburg, Peter H.
Harrison, Paul J.
Gilmour, Gary
Bannerman, David M.
Sanderson, David J.
Isles, Anthony; Pokaż więcej
Źródło:: European Journal of Neuroscience. Apr2017, Vol. 45 Issue 7, p912-921. 10p. 1 Chart, 4 Graphs.

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Skocz do pozycji: 11.

Tytuł:: Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation.
Autorzy:: Hernandez-Martinez JM; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, West Medical Building, Glasgow, G12 8QQ, UK.
Forrest CM; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, West Medical Building, Glasgow, G12 8QQ, UK.
Darlington LG; Internal Medicine, Ashtead Hospital, Ashtead, UK.
Smith RA; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, West Medical Building, Glasgow, G12 8QQ, UK.
Stone TW; Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, West Medical Building, Glasgow, G12 8QQ, UK.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2017 Mar; Vol. 45 (5), pp. 700-711. Date of Electronic Publication: 2017 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Neuronal Outgrowth*
Neurites/*drug effects
Quinolinic Acid/*pharmacology
Receptors, N-Methyl-D-Aspartate/*agonists
Cell Line, Tumor ; Dizocilpine Maleate/pharmacology ; Doublecortin Domain Proteins ; Enzyme Inhibitors/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Humans ; Microtubule-Associated Proteins/metabolism ; NADPH Oxidases/antagonists & inhibitors ; Neurites/metabolism ; Neuropeptides/metabolism ; Onium Compounds/pharmacology ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Tretinoin/pharmacology ; Tubulin/metabolism

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Skocz do pozycji: 12.

Tytuł:: Functional properties of spontaneous excitatory currents and encoding of light/dark transitions in horizontal cells of the mouse retina.
Autorzy:: Feigenspan A; Department of Biology, Division of Animal Physiology, University of Erlangen-Nuernberg, Staudtstrasse 5, D-91058, Erlangen, German.
Babai N; Department of Biology, Division of Animal Physiology, University of Erlangen-Nuernberg, Staudtstrasse 5, D-91058, Erlangen, German.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2015 Nov; Vol. 42 (9), pp. 2615-32. Date of Electronic Publication: 2015 Jul 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Excitatory Postsynaptic Potentials*
Retinal Cone Photoreceptor Cells/*physiology
Retinal Horizontal Cells/*physiology
6-Cyano-7-nitroquinoxaline-2,3-dione/pharmacology ; Animals ; Benzodiazepines/pharmacology ; Dendrites ; Excitatory Amino Acid Antagonists/pharmacology ; Glutamates/pharmacology ; Glutamic Acid/physiology ; Mice ; Mice, Transgenic ; Neural Pathways/cytology ; Neural Pathways/physiology ; Photic Stimulation ; Receptors, AMPA/agonists ; Receptors, AMPA/physiology ; Receptors, Kainic Acid/agonists ; Receptors, Kainic Acid/physiology ; Retinal Cone Photoreceptor Cells/cytology ; Retinal Horizontal Cells/cytology

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Skocz do pozycji: 13.

Tytuł:: Mechanisms regulating spill-over of synaptic glutamate to extrasynaptic NMDA receptors in mouse substantia nigra dopaminergic neurons.
Autorzy:: Wild AR; Department of Physiology, Development & Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK.
Bollands M; Department of Physiology, Development & Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK.
Morris PG; Department of Physiology, Development & Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK.
Jones S; Department of Physiology, Development & Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2015 Nov; Vol. 42 (9), pp. 2633-43. Date of Electronic Publication: 2015 Oct 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Excitatory Postsynaptic Potentials*/drug effects
Dopaminergic Neurons/*physiology
Glutamic Acid/*physiology
Receptors, N-Methyl-D-Aspartate/*physiology
Substantia Nigra/*physiology
Synapses/*physiology
Amino Acids/pharmacology ; Animals ; Aspartic Acid/pharmacology ; Dizocilpine Maleate/pharmacology ; Dopaminergic Neurons/drug effects ; Electric Stimulation ; Excitatory Amino Acid Antagonists/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Synapses/drug effects ; Xanthenes/pharmacology

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Skocz do pozycji: 14.

Tytuł:: Muscarinic modulation of TREK currents in mouse sympathetic superior cervical ganglion neurons.
Autorzy:: Rivas-Ramírez P; Department of Functional Biology and Health Sciences, Faculty of Biology - CINBIO-IBIV, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain.
Cadaveira-Mosquera A; Department of Functional Biology and Health Sciences, Faculty of Biology - CINBIO-IBIV, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain.
Lamas JA; Department of Functional Biology and Health Sciences, Faculty of Biology - CINBIO-IBIV, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain.
Reboreda A; Department of Functional Biology and Health Sciences, Faculty of Biology - CINBIO-IBIV, University of Vigo, Campus Lagoas-Marcosende, 36310, Vigo, Spain.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2015 Jul; Vol. 42 (2), pp. 1797-807. Date of Electronic Publication: 2015 May 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Neurons/*drug effects
Potassium Channels, Tandem Pore Domain/*metabolism
Receptors, Muscarinic/*metabolism
Superior Cervical Ganglion/*cytology
Animals ; Cells, Cultured ; Cesium/pharmacology ; Chlorides/pharmacology ; Cholinergic Agents/pharmacology ; Electric Stimulation ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; Male ; Mice ; Oxotremorine/analogs & derivatives ; Oxotremorine/pharmacology ; Patch-Clamp Techniques ; Pertussis Toxin/pharmacology ; Potassium Channel Blockers/pharmacology ; Riluzole/pharmacology ; Sodium Channel Blockers/pharmacology ; Tetraethylammonium/pharmacology ; Tetrodotoxin/pharmacology

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Skocz do pozycji: 15.

Tytuł:: Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.
Autorzy:: Jarosch MS; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Gebhardt C; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Fano S; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Huchzermeyer C; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Ul Haq R; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Behrens CJ; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.
Heinemann U; Institute for Neurophysiology, Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany.; Excellence Cluster NeuroCure, Berlin, Germany.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2015 Jul; Vol. 42 (2), pp. 1808-17. Date of Electronic Publication: 2015 Jun 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CA3 Region, Hippocampal/*physiology
Excitatory Postsynaptic Potentials/*physiology
Hypoxia/*physiopathology
Nerve Net/*physiology
Pyramidal Cells/*physiology
Adenosine/metabolism ; Adenosine A1 Receptor Antagonists/pharmacology ; Animals ; Bicuculline/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Excitatory Postsynaptic Potentials/drug effects ; Female ; GABA-A Receptor Antagonists/pharmacology ; In Vitro Techniques ; Nerve Net/drug effects ; Oxygen/metabolism ; Patch-Clamp Techniques ; Quinoxalines/pharmacology ; Rats ; Rats, Wistar ; Valine/analogs & derivatives ; Valine/pharmacology ; Xanthines/pharmacology