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Tytuł :
Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Autorzy :
Lau B; Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120 Heidelberg, Germany.
Cheng J; Gene Center, Department of Biochemistry and Center for Integrated Protein Science Munich (CiPSM), Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377 Munich, Germany.
Flemming D; Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120 Heidelberg, Germany.
La Venuta G; Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120 Heidelberg, Germany.
Berninghausen O; Gene Center, Department of Biochemistry and Center for Integrated Protein Science Munich (CiPSM), Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377 Munich, Germany.
Beckmann R; Gene Center, Department of Biochemistry and Center for Integrated Protein Science Munich (CiPSM), Ludwig-Maximilians-Universität München, Feodor-Lynen-Straße 25, 81377 Munich, Germany. Electronic address: .
Hurt E; Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120 Heidelberg, Germany. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Jan 21; Vol. 81 (2), pp. 293-303.e4. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DEAD-box RNA Helicases/*chemistry
Endoribonucleases/*chemistry
Exonucleases/*chemistry
Exosome Multienzyme Ribonuclease Complex/*ultrastructure
RNA, Ribosomal, 18S/*chemistry
Ribosomes/*ultrastructure
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*chemistry
Binding Sites ; Cryoelectron Microscopy ; DEAD-box RNA Helicases/genetics ; DEAD-box RNA Helicases/metabolism ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Exonucleases/genetics ; Exonucleases/metabolism ; Exosome Multienzyme Ribonuclease Complex/genetics ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Models, Molecular ; Protein Binding ; Protein Biosynthesis ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; RNA Stability ; RNA, Ribosomal, 18S/genetics ; RNA, Ribosomal, 18S/metabolism ; Ribosomes/genetics ; Ribosomes/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Yeast RNA exosome activity is necessary for maintaining cell wall stability through proper protein glycosylation.
Autorzy :
Novačić A; Laboratory of Biochemistry, Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Beauvais V; Centre de Biophysique Moléculaire, UPR 4301 du CNRS, 45071 Orléans, France.
Oskomić M; Laboratory of Biochemistry, Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Štrbac L; Laboratory of Biochemistry, Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
Dantec AL; Centre de Biophysique Moléculaire, UPR 4301 du CNRS, 45071 Orléans, France.
Rahmouni AR; Centre de Biophysique Moléculaire, UPR 4301 du CNRS, 45071 Orléans, France.
Stuparević I; Laboratory of Biochemistry, Department of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
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Źródło :
Molecular biology of the cell [Mol Biol Cell] 2021 Mar 01; Vol. 32 (5), pp. 363-375. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exosome Multienzyme Ribonuclease Complex/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Catalytic Domain ; Cell Wall/metabolism ; Cell Wall/physiology ; DNA-Binding Proteins/metabolism ; Exosome Multienzyme Ribonuclease Complex/genetics ; Exosomes/genetics ; Exosomes/metabolism ; Gene Expression ; Glycosylation ; Nuclear Proteins/metabolism ; RNA Stability ; RNA-Binding Proteins/metabolism ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells.
Autorzy :
Laffleur B; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Lim J; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Pharmacy, School of Pharmacy, Jeonbuk National University, Jeonju, South Korea.
Zhang W; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Chen Y; Division of Life Science, Department of Chemical and Biological Engineering, Center for Systems Biology and Human Health, and State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong, China.
Pefanis E; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Bizarro J; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Batista CR; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Wu L; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Economides AN; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Wang J; Division of Life Science, Department of Chemical and Biological Engineering, Center for Systems Biology and Human Health, and State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong, China.
Basu U; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. .
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Źródło :
Nature genetics [Nat Genet] 2021 Feb; Vol. 53 (2), pp. 230-242. Date of Electronic Publication: 2021 Feb 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*physiology
Exosome Multienzyme Ribonuclease Complex/*genetics
RNA, Untranslated/*genetics
Somatic Hypermutation, Immunoglobulin/*physiology
Animals ; B-Lymphocytes/drug effects ; CCCTC-Binding Factor/genetics ; CCCTC-Binding Factor/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Chromosomal Proteins, Non-Histone/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Embryonic Stem Cells/physiology ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/genetics ; Green Fluorescent Proteins/genetics ; Mice, Knockout ; Mice, Transgenic ; Mutation ; RNA Processing, Post-Transcriptional ; Recombination, Genetic ; Tamoxifen/pharmacology
Czasopismo naukowe
Tytuł :
Post-transcriptional control of cellular differentiation by the RNA exosome complex.
Autorzy :
Fraga de Andrade I; Wisconsin Blood Cancer Research Institute, Department of Cell and Regenerative Biology, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, 4009 WIMR, Madison, WI 53705, USA.
Mehta C; Wisconsin Blood Cancer Research Institute, Department of Cell and Regenerative Biology, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, 4009 WIMR, Madison, WI 53705, USA.
Bresnick EH; Wisconsin Blood Cancer Research Institute, Department of Cell and Regenerative Biology, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, 4009 WIMR, Madison, WI 53705, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Dec 02; Vol. 48 (21), pp. 11913-11928.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Processing, Post-Translational*
Chromatin/*chemistry
Erythrocytes/*metabolism
Exosome Multienzyme Ribonuclease Complex/*metabolism
RNA, Messenger/*genetics
RNA-Binding Proteins/*genetics
Animals ; Cell Differentiation ; Chromatin/metabolism ; Chromatin/ultrastructure ; DNA Repair ; Erythrocytes/ultrastructure ; Exosome Multienzyme Ribonuclease Complex/genetics ; Exosome Multienzyme Ribonuclease Complex/ultrastructure ; Genomic Instability ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/ultrastructure ; Humans ; Mice ; Organ Specificity ; Protein Subunits/genetics ; Protein Subunits/metabolism ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Autorzy :
Kawabe Y; Psychiatry, Graduate School of Medicine, Osaka University, Osaka, Japan.
Mori K; Psychiatry, Graduate School of Medicine, Osaka University, Osaka, Japan.
Yamashita T; Psychiatry, Graduate School of Medicine, Osaka University, Osaka, Japan.
Gotoh S; Psychiatry, Graduate School of Medicine, Osaka University, Osaka, Japan.
Ikeda M; Psychiatry, Graduate School of Medicine, Osaka University, Osaka, Japan.
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Źródło :
The EMBO journal [EMBO J] 2020 Oct 01; Vol. 39 (19), pp. e102700. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Stability*
Repetitive Sequences, Nucleic Acid*
Amyotrophic Lateral Sclerosis/*metabolism
C9orf72 Protein/*metabolism
Exoribonucleases/*metabolism
Exosome Multienzyme Ribonuclease Complex/*metabolism
Frontotemporal Lobar Degeneration/*metabolism
RNA/*metabolism
Amyotrophic Lateral Sclerosis/genetics ; C9orf72 Protein/genetics ; Exoribonucleases/genetics ; Exosome Multienzyme Ribonuclease Complex/genetics ; Frontotemporal Lobar Degeneration/genetics ; HeLa Cells ; Humans ; RNA/genetics
Czasopismo naukowe
Tytuł :
Nucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function.
Autorzy :
Okuda EK; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Gonzales-Zubiate FA; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Gadal O; Laboratoire de Biologie Moléculaire Eucaryote, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, Toulouse, France.
Oliveira CC; Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Aug 07; Vol. 295 (32), pp. 11195-11213. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Processing, Post-Transcriptional*
Cell Nucleolus/*metabolism
Exosome Multienzyme Ribonuclease Complex/*metabolism
Exosomes/*metabolism
RNA Precursors/*metabolism
RNA, Fungal/*metabolism
RNA, Transfer/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Amino Acid Sequence ; Exosome Multienzyme Ribonuclease Complex/chemistry ; Protein Transport ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/chemistry ; Subcellular Fractions/metabolism
Czasopismo naukowe
Tytuł :
Exosomal miRNA profiling before and after surgery revealed potential diagnostic and prognostic markers for lung adenocarcinoma.
Autorzy :
Xue X; Department of Respiratory and Critical Care, Chinese PLA General Hospital, Beijing 100853, China.; Department of Respiratory and Critical Care, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Wang C; Shanghai Institute of Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Xue Z; Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Wen J; Department of Thoracic Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Han J; Department of Radiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China.
Ma X; School of Clinical Medicine, Weifang Medical University, Shandong 261042, China.
Zang X; Microbiology Department, Chinese PLA General Hospital, Beijing 100853, China.
Deng H; Department of Respiratory and Critical Care, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Guo R; Department of Respiratory and Critical Care, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Asuquo IP; Departments of Radiology, Jinzhou Medical University, Jinzhou 121001, China.
Qin C; Department of Respiratory and Critical Care, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Wang H; Department of Respiratory and Critical Care, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Gao Q; Tianjin Institute of Environmental and Operational Medicine, Tianjin 300050, China.
Liu S; Shanghai Institute of Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China.
Wang J; Department of Respiratory and Critical Care, Chinese PLA General Hospital, Beijing 100853, China.
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Źródło :
Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2020 Mar 18; Vol. 52 (3), pp. 281-293.
Typ publikacji :
Journal Article
MeSH Terms :
Adenocarcinoma of Lung/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
MicroRNAs/*genetics
Adenocarcinoma/pathology ; Adenocarcinoma of Lung/diagnosis ; Adenocarcinoma of Lung/mortality ; Adult ; Aged ; Biomarkers, Tumor/genetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Exosome Multienzyme Ribonuclease Complex/blood ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/genetics ; Female ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Kaplan-Meier Estimate ; Lung Neoplasms/pathology ; Male ; MicroRNAs/blood ; MicroRNAs/metabolism ; Middle Aged ; Prognosis ; ROC Curve
Czasopismo naukowe
Tytuł :
RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels.
Autorzy :
Müller JS; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Burns DT; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Griffin H; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
Wells GR; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Zendah RA; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Munro B; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Schneider C; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Horvath R; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK .; Department of Clinical Neurosciences, University of Cambridge School of Clinical Medicine, Cambridge, UK.
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Źródło :
Life science alliance [Life Sci Alliance] 2020 Jun 11; Vol. 3 (8). Date of Electronic Publication: 2020 Jun 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebellar Diseases/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
Ribosomes/*metabolism
Adult ; Animals ; Cell Line, Tumor ; Cerebellar Diseases/physiopathology ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/genetics ; Female ; Homozygote ; Humans ; Male ; Mutation ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Ribosomes/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Zebrafish/genetics ; Zebrafish Proteins/genetics
SCR Disease Name :
Pontocerebellar Hypoplasia
Czasopismo naukowe
Tytuł :
EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells.
Autorzy :
Yoshino S; Division of Molecular Pathology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Matsui Y; Biomedical and Health Informatics Unit, Department of Integrated Health Science, Nagoya University Graduate School of Medicine, Daiko-Minami, Higashi-ku, Nagoya, Aichi, Japan.
Fukui Y; Division of Cellular and Molecular Biology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Seki M; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan.
Yamaguchi K; Division of Clinical Genome Research, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Kanamori A; Division of Cellular and Molecular Biology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Saitoh Y; Division of Cellular and Molecular Biology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.; Center for Medical Education, Teikyo University of Science, Senjusakuragi, Adachi-ku, Tokyo, Japan.
Shimamura T; Division of Systems Biology, Nagoya University Graduate School of Medicine, Tsurumai-cho, Nagoya, Japan.
Suzuki Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan.
Furukawa Y; Division of Clinical Genome Research, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Kaneko S; Department of System Biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takaramachi, Kanazawa, Ishikawa, Japan.
Seiki M; Division of Cancer Cell Research, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Murakami Y; Division of Molecular Pathology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Inoue JI; Division of Cellular and Molecular Biology, the Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan.
Sakamoto T; Department of System Biology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takaramachi, Kanazawa, Ishikawa, Japan. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 09; Vol. 10 (1), pp. 9275. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exosome Multienzyme Ribonuclease Complex/*metabolism
RNA-Binding Proteins/*metabolism
Stress, Physiological/*physiology
APOBEC-3G Deaminase/genetics ; APOBEC-3G Deaminase/metabolism ; Animals ; Binding Sites ; Cell Line, Tumor ; Cytoplasmic Structures/metabolism ; DNA Damage ; Endoplasmic Reticulum Stress ; Exosome Multienzyme Ribonuclease Complex/genetics ; Exosomes/genetics ; Exosomes/metabolism ; Female ; Humans ; Mice, Inbred BALB C ; Oxidative Stress ; RNA-Binding Proteins/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes.
Autorzy :
Wu D; Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
Dean J; Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 04; Vol. 48 (10), pp. 5349-5365.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
Oogenesis*
Transcriptome*
Exoribonucleases/*physiology
Exosome Multienzyme Ribonuclease Complex/*physiology
Oocytes/*growth & development
Oocytes/*metabolism
Animals ; CDC2 Protein Kinase/metabolism ; Exoribonucleases/genetics ; Exosome Multienzyme Ribonuclease Complex/genetics ; Female ; Infertility, Female/genetics ; Intracellular Membranes/metabolism ; Mice ; Nuclear Lamina/metabolism ; Poly A ; RNA/metabolism ; RNA Precursors/metabolism ; RNA Processing, Post-Transcriptional ; RNA, Ribosomal/metabolism ; RNA-Seq
Czasopismo naukowe
Tytuł :
Exosomal miRNAs in osteoarthritis.
Autorzy :
Mihanfar A; Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.; Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
Shakouri SK; Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Khadem-Ansari MH; Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Fattahi A; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences Tabriz, Tabriz, Iran.
Latifi Z; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.; Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Nejabati HR; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran. .; Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. .; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran. .; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
Nouri M; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran. .; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences Tabriz, Tabriz, Iran. .; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
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Źródło :
Molecular biology reports [Mol Biol Rep] 2020 Jun; Vol. 47 (6), pp. 4737-4748. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Exosome Multienzyme Ribonuclease Complex/*genetics
MicroRNAs/*genetics
Osteoarthritis/*genetics
Exosome Multienzyme Ribonuclease Complex/physiology ; Exosomes/genetics ; Exosomes/metabolism ; Humans ; MicroRNAs/metabolism ; Osteoarthritis/physiopathology ; Osteoarthritis/therapy
Czasopismo naukowe
Tytuł :
Comprehensive analysis of dysregulated exosomal long non-coding RNA networks associated with arteriovenous malformations.
Autorzy :
Li X; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Gui Z; Department of Department of Oral & Cranio-maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Han Y; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Yang X; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Wang Z; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Zheng L; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Zhang L; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Wang D; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China.
Fan X; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China. Electronic address: .
Su L; Department of Interventional Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639 Zhi Zao Ju Rd, Shanghai 200011, Shanghai, People's Republic of China. Electronic address: .
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Źródło :
Gene [Gene] 2020 May 15; Vol. 738, pp. 144482. Date of Electronic Publication: 2020 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Arteriovenous Malformations/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
RNA, Long Noncoding/*genetics
Adult ; China ; Computational Biology/methods ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/genetics ; Exosomes/metabolism ; Female ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic/genetics ; Gene Ontology ; Gene Regulatory Networks/genetics ; Humans ; Male ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Messenger/genetics ; Signal Transduction/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Novel EXOSC9 variants cause pontocerebellar hypoplasia type 1D with spinal motor neuronopathy and cerebellar atrophy.
Autorzy :
Sakamoto M; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.; Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Iwama K; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.; Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
Sekiguchi F; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.
Mashimo H; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.
Kumada S; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.
Ishigaki K; Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan.
Okamoto N; Department of Medical Genetics, Osaka Women's and Children's Hospital, Osaka, Japan.
Behnam M; Medical Genetics Research Center of Genome, Isfahan University of Medical Sciences, Isfahan, Iran.
Ghadami M; Department of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.; Cardiac Primary Research Center, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Koshimizu E; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.
Miyatake S; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.; Clinical Genetics Department, Yokohama City University Hospital, Yokohama, Japan.
Mitsuhashi S; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.
Mizuguchi T; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.
Takata A; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan.
Saitsu H; Department of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Miyake N; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan. .
Matsumoto N; Department of Human Genetics, Graduate school of medicine, Yokohama City University, Yokohama, Japan. .
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Źródło :
Journal of human genetics [J Hum Genet] 2021 Apr; Vol. 66 (4), pp. 401-407. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Mutation*
Atrophy/*pathology
Cerebellar Diseases/*pathology
Exosome Multienzyme Ribonuclease Complex/*genetics
Motor Neuron Disease/*pathology
Muscular Atrophy, Spinal/*pathology
Olivopontocerebellar Atrophies/*pathology
RNA-Binding Proteins/*genetics
Atrophy/complications ; Atrophy/genetics ; Cerebellar Diseases/complications ; Cerebellar Diseases/genetics ; Female ; Genetic Association Studies ; Humans ; Infant ; Male ; Motor Neuron Disease/complications ; Motor Neuron Disease/genetics ; Muscular Atrophy, Spinal/complications ; Muscular Atrophy, Spinal/genetics ; Olivopontocerebellar Atrophies/complications ; Olivopontocerebellar Atrophies/genetics ; Pedigree
SCR Disease Name :
Pontocerebellar Hypoplasia Type 1
Czasopismo naukowe
Tytuł :
Exonuclease domain mutants of yeast DIS3 display genome instability.
Autorzy :
Milbury KL; a Terry Fox Laboratory , British Columbia Cancer Agency , Vancouver , Canada.
Paul B; b Department of Cell Biology , University of Alberta , Edmonton , Canada.
Lari A; b Department of Cell Biology , University of Alberta , Edmonton , Canada.
Fowler C; a Terry Fox Laboratory , British Columbia Cancer Agency , Vancouver , Canada.
Montpetit B; b Department of Cell Biology , University of Alberta , Edmonton , Canada.; c Department of Viticulture and Enology , University of California , Davis , CA , USA.
Stirling PC; a Terry Fox Laboratory , British Columbia Cancer Agency , Vancouver , Canada.; d Department of Medical Genetics , University of British Columbia , Vancouver , BC , Canada.
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Źródło :
Nucleus (Austin, Tex.) [Nucleus] 2019 Dec; Vol. 10 (1), pp. 21-32.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Exonucleases/*genetics
Exosome Multienzyme Ribonuclease Complex/*chemistry
Exosome Multienzyme Ribonuclease Complex/*genetics
Genomic Instability/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*genetics
Exonucleases/chemistry ; Exonucleases/metabolism ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Protein Domains/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł :
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling.
Autorzy :
Ulmke PA; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.
Xie Y; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.; Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Gannan Medical University, 341000 Ganzhou, The People's Republic of China.
Sokpor G; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.; Department of Human Genetics, Ruhr University of Bochum, Bochum 44801, Germany.
Pham L; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.; Department of Human Genetics, Ruhr University of Bochum, Bochum 44801, Germany.
Shomroni O; Microarray and Deep-Sequencing Core Facility, Georg-August- University Goettingen, Goettingen 37075, Germany.
Berulava T; German Center for Neurodegenerative Diseases, Goettingen 37075, Germany.
Rosenbusch J; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.
Basu U; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Fischer A; German Center for Neurodegenerative Diseases, Goettingen 37075, Germany.; Department for Psychiatry and Psychotherapy, University Medical Center, Georg-August-University Goettingen, Goettingen 37075, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Goettingen, Goettingen 37075, Germany.
Nguyen HP; Department of Human Genetics, Ruhr University of Bochum, Bochum 44801, Germany.
Staiger JF; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany.
Tuoc T; University Medical Center, Georg-August- University Goettingen, Goettingen 37075, Germany .; Department of Human Genetics, Ruhr University of Bochum, Bochum 44801, Germany.
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Źródło :
Development (Cambridge, England) [Development] 2021 Feb 08; Vol. 148 (3). Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Cell Survival/*physiology
Exosomes/*genetics
Exosomes/*metabolism
Prosencephalon/*growth & development
Tumor Suppressor Protein p53/*metabolism
Animals ; Apoptosis ; Apoptosis Regulatory Proteins ; Computational Biology ; Exoribonucleases/genetics ; Exosome Multienzyme Ribonuclease Complex/genetics ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Prosencephalon/pathology ; RNA/metabolism ; RNA Stability ; Signal Transduction/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins
Czasopismo naukowe
Tytuł :
Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis.
Autorzy :
Yang X; Department travellers of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.; Program in Cancer Biology, Stanford School of Medicine, Stanford, CA 94305, USA.
Bayat V; Department travellers of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.
DiDonato N; Institute for Clinical Genetics, TU Dresden, Dresden, Germany.
Zhao Y; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
Zarnegar B; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
Siprashvili Z; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
Lopez-Pajares V; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
Sun T; Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA.
Tao S; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
Li C; School of Life Sciences, Peking University, Beijing 100871, China.
Rump A; Institute for Clinical Genetics, TU Dresden, Dresden, Germany.
Khavari P; Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.; Program in Cancer Biology, Stanford School of Medicine, Stanford, CA 94305, USA.
Lu B; Department travellers of Pathology, Stanford School of Medicine, Stanford, CA 94305, USA.; Program in Cancer Biology, Stanford School of Medicine, Stanford, CA 94305, USA.
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Źródło :
Human molecular genetics [Hum Mol Genet] 2020 Mar 13; Vol. 29 (4), pp. 541-553.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Exosome Multienzyme Ribonuclease Complex/*genetics
RNA-Binding Proteins/*genetics
Animals ; Autophagy/genetics ; Disease Models, Animal ; Drosophila/genetics ; Dwarfism/genetics ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Exosomes/metabolism ; Female ; Genomics/methods ; HEK293 Cells ; Hearing Loss/genetics ; Humans ; Male ; Mutation, Missense/genetics ; Phenotype ; RNA/metabolism ; RNA-Binding Proteins/metabolism ; Retinitis Pigmentosa/genetics ; Syndrome
Czasopismo naukowe
Tytuł :
Identification of lung adenocarcinoma-specific exosome RNAs in peripheral blood by RNA-Seq analysis.
Autorzy :
Liu XQ; Department of Internal Medicine V, Division of Respiratory Medicine and Thoracic Oncology, Ludwig-Maximilians University (LMU), Thoracic Oncology Centre Munich; Comprehensive Pneumology Center Munich, Member of the German Center for Lung Research (DZL), Munich, Bavaria, Germany. .
Tufman A
Kiefl R
Li GF
Ma QL
Huber RM
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Źródło :
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2020 Feb; Vol. 24 (4), pp. 1877-1886.
Typ publikacji :
Journal Article
MeSH Terms :
Sequence Analysis, RNA*
Adenocarcinoma of Lung/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
Lung Neoplasms/*genetics
Adenocarcinoma of Lung/blood ; Adenocarcinoma of Lung/diagnosis ; Computational Biology ; Exosome Multienzyme Ribonuclease Complex/blood ; Exosomes/metabolism ; Humans ; Lung Neoplasms/blood ; Lung Neoplasms/diagnosis
Czasopismo naukowe
Tytuł :
Comprehensive characterization of the rRNA metabolism-related genes in human cancer.
Autorzy :
Cui K; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China.
Liu C; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China.
Li X; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China.
Zhang Q; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China.; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China.
Li Y; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, China. .; Medical Research Institute, School of Medicine, Wuhan University, Wuhan, 430071, China. .
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Źródło :
Oncogene [Oncogene] 2020 Jan; Vol. 39 (4), pp. 786-800. Date of Electronic Publication: 2019 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Copy Number Variations*
Gene Amplification*
Exosome Multienzyme Ribonuclease Complex/*genetics
Neoplasms/*pathology
RNA, Ribosomal/*genetics
RNA, Ribosomal/*metabolism
RNA-Binding Proteins/*genetics
Adult ; Aged ; Animals ; Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Databases, Genetic ; Disease Models, Animal ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Neoplasms/genetics ; Neoplasms/metabolism ; RNA-Binding Proteins/metabolism ; Survival Rate
Czasopismo naukowe
Tytuł :
A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells.
Autorzy :
da Costa PJ; Department of Human Genetics, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal.
Menezes J; Department of Human Genetics, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal.
Saramago M; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
García-Moreno JF; Department of Human Genetics, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal.
Santos HA; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal.
Gama-Carvalho M; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal.
Arraiano CM; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Viegas SC; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal. Electronic address: .
Romão L; Department of Human Genetics, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal; University of Lisboa, Faculty of Sciences, BioISI - Biosystems and Integrative Sciences Institute, Lisboa, Portugal. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Oct 22; Vol. 518 (4), pp. 664-671. Date of Electronic Publication: 2019 Aug 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exoribonucleases/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
Nonsense Mediated mRNA Decay/*genetics
RNA, Messenger/*genetics
DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Exoribonucleases/metabolism ; Exosome Multienzyme Ribonuclease Complex/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; RNA Helicases/genetics ; RNA Helicases/metabolism ; RNA Nucleotidyltransferases/genetics ; RNA Nucleotidyltransferases/metabolism ; RNA, Messenger/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Uridine Monophosphate/metabolism
Czasopismo naukowe
Tytuł :
The MTNR1A mRNA is stabilized by the cytoplasmic hnRNPL in renal tubular cells.
Autorzy :
Huang YS; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Lu KC; Division of Nephrology, Department of Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Chao HW; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chen A; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Chao TK; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Guo CY; Division of Nephrology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Hsieh HY; Division of Nephrology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Shih HM; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli County, Taiwan.
Sytwu HK; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan.; Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan.
Wu CC; Division of Nephrology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan.
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Źródło :
Journal of cellular physiology [J Cell Physiol] 2021 Mar; Vol. 236 (3), pp. 2023-2035. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytoplasm/*metabolism
Heterogeneous-Nuclear Ribonucleoprotein L/*metabolism
Kidney Tubules/*metabolism
Receptor, Melatonin, MT1/*genetics
Animals ; Cell Line ; Circadian Rhythm/genetics ; Cyclic AMP Response Element-Binding Protein/metabolism ; Epithelial Cells/metabolism ; Exoribonucleases/metabolism ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Glomerulonephritis, Membranous/genetics ; Glomerulonephritis, Membranous/pathology ; Humans ; Kidney Tubules/pathology ; Mice, Inbred BALB C ; Models, Biological ; Open Reading Frames/genetics ; Phosphorylation ; RNA Stability/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptor, Melatonin, MT1/metabolism ; Repetitive Sequences, Nucleic Acid/genetics ; Up-Regulation/genetics
Czasopismo naukowe

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